MCID: PRC011
MIFTS: 35

Parachordoma malady

Cancer diseases category
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Summaries for Parachordoma

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MalaCards based summary: Parachordoma is related to chordoma and sarcoma. An important gene associated with Parachordoma is T (T, brachyury homolog (mouse)), and among its related pathways is Striated Muscle Contraction. The compounds eosin and orcein have been mentioned in the context of this disorder. Affiliated tissues include kidney.

Aliases & Classifications for Parachordoma

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Parachordoma, Aliases & Descriptions:

Name: Parachordoma 8 10 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


External Ids:

Disease Ontology8 DOID:2647
NCIt39 C6581

Related Diseases for Parachordoma

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Diseases related to Parachordoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 98)
idRelated DiseaseScoreTop Affiliating Genes
1chordoma29.9DES, MUC1, CEACAM3, S100B, KRT7
2sarcoma29.8DES, MUC1, S100B
3chondrosarcoma29.7S100B, CEACAM3, MUC1, DES
4paraganglioma10.5DES
5chest wall parachordoma10.4
6metanephric adenoma10.4KRT7
7nephrogenic adenoma10.4KRT7
8synovial sarcoma10.3KRT7
9cystadenocarcinoma10.3MUC1, CEACAM3
10pulmonary alveolar proteinosis10.3MUC1, CEACAM3
11mesenchymal chondrosarcoma10.3DES, MUC1
12desmoplastic small round cell tumor10.3DES, MUC1
13spindle cell carcinoma10.3DES, MUC1
14papilloma10.3KRT20
15sertoli cell tumor10.3DES, MUC1
16myoepithelioma10.3
17malignant pleural mesothelioma10.3MUC1, CEACAM3
18rhabdoid tumor10.3DES, MUC1
19kidney cancer10.3KRT7
20gastrointestinal carcinoma10.2CEACAM3, KRT20
21merkel cell carcinoma10.2MUC1, KRT20
22rectal neoplasm10.2CEACAM3, KRT20
23sertoli-leydig cell tumor10.2KRT7, MUC1
24bowen syndrome10.2CEACAM3, KRT7
25epithelioid sarcoma10.2MUC1, KRT7
26cystadenoma10.2CEACAM3, KRT7
27secretory meningioma10.2MUC1, KRT7
28bladder adenocarcinoma10.2KRT7, KRT20
29signet ring cell adenocarcinoma10.2KRT7, KRT20
30ovarian brenner tumor10.2KRT7, KRT20
31gallbladder cancer10.2KRT7, CEACAM3
32pancreatic ductal carcinoma10.2KRT7, KRT20
33mucoepidermoid carcinoma10.2KRT7, MUC1
34fibrous meningioma10.1MUC1, S100B
35pseudomyxoma peritonei10.1KRT20, KRT7
36bronchiolo-alveolar adenocarcinoma10.1KRT20, KRT7
37choroid plexus papilloma10.1MUC1, S100B
38anaplastic ependymoma10.1MUC1, S100B
39cervical adenocarcinoma10.1KRT7, KRT20
40meningioma10.1MUC1, S100B
41neuroendocrine tumor10.1CEACAM3, KRT20
42renal clear cell carcinoma10.1KRT7, MUC1
43perineurioma10.1MUC1, S100B
44cutaneous fibrous histiocytoma10.1DES, S100B
45carcinoid syndrome10.1KRT20, CEACAM3, MUC1
46granular cell tumor10.1DES, S100B
47fibrous histiocytoma10.1DES, S100B
48hemangioblastoma10.1S100B, MUC1
49malignant peripheral nerve sheath tumor10.1MUC1, S100B
50thymus cancer10.1MUC1, CEACAM3, KRT7

Graphical network of the top 20 diseases related to Parachordoma:



Diseases related to parachordoma

Symptoms for Parachordoma

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Drugs & Therapeutics for Parachordoma

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Drug clinical trials:

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Genetic Tests for Parachordoma

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Anatomical Context for Parachordoma

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MalaCards organs/tissues related to Parachordoma:

32
Kidney

Animal Models for Parachordoma or affiliated genes

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Publications for Parachordoma

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Articles related to Parachordoma:

(show all 43)
idTitleAuthorsYear
1
Parachordoma/myoepithelioma of the kidney: first report of a myxoid mimicry in an unusual location. (24696746)
2014
2
A case of parachordoma on the chest wall and literature review. (24135242)
2013
3
Parachordoma/myoepithelioma. (22618759)
2013
4
Parachordoma of soft tissues of the arm: a very rare tumour. (24083043)
2013
5
Huge pelvic parachordoma: fine needle aspiration cytology and histological differential diagnosis. (23372917)
2012
6
Clinical and radiological presentations of pelvic parachordoma. (22532921)
2012
7
Intraneural parachordoma of the arm with regional metastases. (21499979)
2011
8
Presacral parachordoma causing intestinal obstruction in a patient with renal failure: Report of a case. (21922364)
2011
9
Axial chordoma and parachordoma (soft tissue chordoma): two of a kind: report of two cases with primary diagnosis on fine-needle cytology samples. (20730897)
2011
10
Parachordoma: a recurrent case and review of the literature. (21630208)
2011
11
Fine needle aspiration appearance of parachordoma. (20306999)
2010
12
Parachordoma of skull. (20303594)
2010
13
Metastatic parachordoma. (19208078)
2009
14
Pulmonary metastases from parachordoma. (19632372)
2009
15
Parachordoma: a very rare tumour of the hand. (20067931)
2009
16
Possible parachordoma in a dog. (19802045)
2009
17
Case report: parachordoma of soft tissues of the arm. (18219545)
2008
18
Brachyury expression in extra-axial skeletal and soft tissue chordomas: a marker that distinguishes chordoma from mixed tumor/myoepithelioma/parachordoma in soft tissue. (18301055)
2008
19
Parachordoma or myoepithelion?: a case report of a rare soft tissue tumor. (17295651)
2007
20
Parachordoma of the gastric serosa: report of a myxoid mimicry in an unusual location. (17652546)
2007
21
Fatal parachordoma. (17260126)
2007
22
Retroperitoneal parachordoma in a patient with a history of recurrent pain. (15863385)
2005
23
Parachordoma is not distinguishable from axial chordoma using immunohistochemistry. (15086843)
2004
24
Parachordoma of tibia--a case report. (15025303)
2003
25
Parachordoma or chordoma periphericum? Case report of a tumor of the thoracic wall. (12827710)
2003
26
Parachordoma with multiple metastases. (12886158)
2003
27
Parachordoma: a case report. (11504379)
2001
28
Parachordoma exists--but what is it? (10809219)
2000
29
Parachordoma of the tibia: report of a rare case. (10782472)
2000
30
Parachordoma is immunohistochemically and cytogenetically distinct from axial chordoma and extraskeletal myxoid chondrosarcoma. (10478665)
1999
31
Chest wall parachordoma. (10609912)
1999
32
Parachordoma: a rare sarcoma with clonal chromosomal changes. (9530345)
1998
33
Cytogenetic analysis of a parachordoma. (9689924)
1998
34
Cutaneous parachordoma. A light microscopic and immunohistochemical report of two cases and review of the literature. (9696295)
1998
35
Parachordoma: a clinicopathologic and immunohistochemical study of four cases of an unusual soft tissue neoplasm. (9869820)
1997
36
Parachordoma. A case report of a very rare soft tissue tumor. (8950765)
1996
37
Parachordoma of the sacrococcygeal region--a neuroepithelial tumor. (8605741)
1995
38
Parachordoma--a clinicopathologic, immunohistochemical, electron microscopic, flow cytometric, and cytogenetic study. (8542507)
1995
39
Parachordoma of the buttock: an immunohistochemical case study and review. (7530308)
1994
40
Parachordoma. (8030773)
1994
41
Parachordoma. (8191635)
1994
42
Parachordoma: an ultrastructural and immunohistochemical study. (8493780)
1993
43
Parachordoma: a new clinicopathologic entity. (907973)
1977

Variations for Parachordoma

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Expression for genes affiliated with Parachordoma

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Expression patterns in normal tissues for genes affiliated with Parachordoma

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Pathways for genes affiliated with Parachordoma

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Pathways related to Parachordoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.6MYH11, DES

Compounds for genes affiliated with Parachordoma

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Compounds related to Parachordoma according to GeneCards/GeneDecks:

(show all 38)
idCompoundScoreTop Affiliating Genes
1eosin4410.0S100B, MUC1
2orcein4410.0DES, S100B
3indium449.9CEACAM3, MUC1
43-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide449.8S100B, DES
5metronidazole44 1110.7MUC1, CEACAM3
6s 100449.7DES, MUC1, S100B
7dtpa449.7CEACAM3, MUC1
8ethanol44 50 24 1112.5S100B, MUC1, DES
9adriamycin449.4CEACAM3, MUC1, DES
10gold449.4DES, MUC1, CEACAM3
11ccl444 2810.4S100B, DES
12acth449.3S100B, CEACAM3, MUC1
13reticulin449.2DES, MUC1, S100B, KRT7
14hyaluronic acid44 2410.2KRT20, MUC1, DES
15methotrexate50 44 1111.2MUC1, CEACAM3, KRT7
16glycogen44 2410.2DES, MUC1, S100B, KRT7
17lactate449.1S100B, CEACAM3, DES
18thymidine44 2410.0DES, MUC1, CEACAM3, S100B
19creatinine449.0DES, MUC1, CEACAM3, S100B
20sialic acid449.0KRT7, S100B, CEACAM3, MUC1
21oxygen44 249.8DES, MUC1, CEACAM3, S100B
22retinoic acid44 249.7DES, MYH11, MUC1, S100B, KRT7
23iron44 249.7KRT20, KRT7, S100B, DES
24doxorubicin44 50 1110.7KRT20, CEACAM3, DES
25nitric oxide44 24 1110.6DES, MYH11, MUC1, CEACAM3, S100B
26glucose448.5KRT7, S100B, CEACAM3, MUC1, DES
27streptavidin448.5KRT20, KRT7, CEACAM3, DES
28formaldehyde44 249.4DES, MUC1, S100B, KRT7, KRT20
29testosterone44 61 24 1111.4DES, MUC1, S100B, KRT7, KRT20
30calcium44 50 24 1111.1DES, MUC1, CEACAM3, S100B, S100P
31b 723447.8MUC1, DES, CEACAM3, S100B, KRT20, KRT7
32mucicarmine447.8KRT20, KRT7, S100B, CEACAM3, MUC1, DES
33tyrosine447.7DES, MUC1, CEACAM3, S100B, KRT7, KRT20
34hematoxylin447.3KRT20, KRT7, S100B, CEACAM3, MUC1, MYH11
35paraffin447.3DES, MYH11, MUC1, CEACAM3, S100B, KRT7
36progesterone44 28 61 24 1111.3DES, MYH11, MUC1, CEACAM3, S100B, KRT7
37vegf447.3DES, MYH11, MUC1, CEACAM3, S100B, KRT7
38estrogen447.3DES, MYH11, MUC1, CEACAM3, S100B, KRT7

GO Terms for genes affiliated with Parachordoma

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Cellular components related to Parachordoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:0058828.5KRT20, KRT7, DES
2cytoplasmGO:0057377.5KRT20, KRT7, S100P, S100B, MUC1, T

Molecular functions related to Parachordoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1calcium-dependent protein bindingGO:0483069.5S100P, S100B
2RNA polymerase II core promoter proximal region sequence-specific DNA bindingGO:0009789.5MUC1, T
3protein bindingGO:0055156.9KRT20, DES, MYH11, MUC1, S100B, S100P

Products for genes affiliated with Parachordoma

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Sources for Parachordoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet