MCID: PRC011
MIFTS: 34

Parachordoma malady

Cancer diseases category
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Summaries for Parachordoma

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33MalaCards
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MalaCards: Parachordoma is related to chordoma and sarcoma. An important gene associated with Parachordoma is T (T, brachyury homolog (mouse)), and among its related pathways is Striated Muscle Contraction. The compounds eosin and orcein have been mentioned in the context of this disorder.

Aliases & Classifications for Parachordoma

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8Disease Ontology, 10DISEASES, 62UMLS, 58SNOMED-CT, 40NCIt
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

parachordoma 8 10 62


External Ids:

Disease Ontology8 DOID:2647
NCIt40 C6581

Related Diseases for Parachordoma

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Parachordoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 98)
idRelated DiseaseScoreTop Affiliating Genes
1chordoma30.4DES, MUC1, CEACAM3, S100B, KRT7
2sarcoma30.0DES, MUC1, S100B
3chondrosarcoma29.9S100B, CEACAM3, MUC1, DES
4chest wall parachordoma10.4
5myoepithelioma10.2
6glomus tumor10.1DES
7metanephric adenoma10.1KRT7
8nephrogenic adenoma10.1KRT7
9synovial sarcoma10.1KRT7
10cystadenocarcinoma10.1MUC1, CEACAM3
11pulmonary alveolar proteinosis10.1MUC1, CEACAM3
12mesenchymal chondrosarcoma10.1DES, MUC1
13desmoplastic small round cell tumor10.1DES, MUC1
14spindle cell carcinoma10.1DES, MUC1
15papilloma10.1KRT20
16sertoli cell tumor10.1DES, MUC1
17malignant pleural mesothelioma10.1MUC1, CEACAM3
18rhabdoid tumor10.1DES, MUC1
19kidney cancer10.1KRT7
20merkel cell carcinoma10.1MUC1, KRT20
21rectal neoplasm10.1CEACAM3, KRT20
22sertoli-leydig cell tumor10.0KRT7, MUC1
23bowen syndrome10.0CEACAM3, KRT7
24epithelioid sarcoma10.0MUC1, KRT7
25cystadenoma10.0CEACAM3, KRT7
26secretory meningioma10.0MUC1, KRT7
27bladder adenocarcinoma10.0KRT7, KRT20
28signet ring cell adenocarcinoma10.0KRT7, KRT20
29ovarian brenner tumor10.0KRT7, KRT20
30gallbladder cancer10.0KRT7, CEACAM3
31pancreatic ductal carcinoma10.0KRT7, KRT20
32mucoepidermoid carcinoma10.0KRT7, MUC1
33fibrous meningioma10.0MUC1, S100B
34pseudomyxoma peritonei10.0KRT20, KRT7
35choroid plexus papilloma10.0MUC1, S100B
36bronchiolo-alveolar adenocarcinoma10.0KRT20, KRT7
37anaplastic ependymoma10.0MUC1, S100B
38cervical adenocarcinoma10.0KRT7, KRT20
39meningioma10.0MUC1, S100B
40neuroendocrine tumor10.0CEACAM3, KRT20
41renal clear cell carcinoma10.0KRT7, MUC1
42cutaneous fibrous histiocytoma10.0DES, S100B
43perineurioma10.0MUC1, S100B
44carcinoid syndrome10.0KRT20, CEACAM3, MUC1
45granular cell tumor10.0DES, S100B
46fibrous histiocytoma10.0DES, S100B
47hemangioblastoma10.0S100B, MUC1
48extraskeletal myxoid chondrosarcoma10.0
49intestinal obstruction10.0
50myxoid chondrosarcoma10.0

Graphical network of the top 20 diseases related to Parachordoma:



Diseases related to parachordoma

Symptoms for Parachordoma

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Drugs & Therapeutics for Parachordoma

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Sources:
42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

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Genetic Tests for Parachordoma

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Anatomical Context for Parachordoma

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Animal Models for Parachordoma or affiliated genes

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Publications for Parachordoma

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52PubMed
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Articles related to Parachordoma:

(show all 42)
idTitleAuthorsYear
1
A case of parachordoma on the chest wall and literature review. (24135242)
2013
2
Parachordoma/myoepithelioma. (22618759)
2013
3
Parachordoma of soft tissues of the arm: a very rare tumour. (24083043)
2013
4
Huge pelvic parachordoma: fine needle aspiration cytology and histological differential diagnosis. (23372917)
2012
5
Clinical and radiological presentations of pelvic parachordoma. (22532921)
2012
6
Intraneural parachordoma of the arm with regional metastases. (21499979)
2011
7
Presacral parachordoma causing intestinal obstruction in a patient with renal failure: Report of a case. (21922364)
2011
8
Axial chordoma and parachordoma (soft tissue chordoma): two of a kind: report of two cases with primary diagnosis on fine-needle cytology samples. (20730897)
2011
9
Parachordoma: a recurrent case and review of the literature. (21630208)
2011
10
Fine needle aspiration appearance of parachordoma. (20306999)
2010
11
Parachordoma of skull. (20303594)
2010
12
Metastatic parachordoma. (19208078)
2009
13
Pulmonary metastases from parachordoma. (19632372)
2009
14
Parachordoma: a very rare tumour of the hand. (20067931)
2009
15
Possible parachordoma in a dog. (19802045)
2009
16
Case report: parachordoma of soft tissues of the arm. (18219545)
2008
17
Brachyury expression in extra-axial skeletal and soft tissue chordomas: a marker that distinguishes chordoma from mixed tumor/myoepithelioma/parachordoma in soft tissue. (18301055)
2008
18
Parachordoma or myoepithelion?: a case report of a rare soft tissue tumor. (17295651)
2007
19
Parachordoma of the gastric serosa: report of a myxoid mimicry in an unusual location. (17652546)
2007
20
Fatal parachordoma. (17260126)
2007
21
Retroperitoneal parachordoma in a patient with a history of recurrent pain. (15863385)
2005
22
Parachordoma is not distinguishable from axial chordoma using immunohistochemistry. (15086843)
2004
23
Parachordoma of tibia--a case report. (15025303)
2003
24
Parachordoma or chordoma periphericum? Case report of a tumor of the thoracic wall. (12827710)
2003
25
Parachordoma with multiple metastases. (12886158)
2003
26
Parachordoma: a case report. (11504379)
2001
27
Parachordoma exists--but what is it? (10809219)
2000
28
Parachordoma of the tibia: report of a rare case. (10782472)
2000
29
Parachordoma is immunohistochemically and cytogenetically distinct from axial chordoma and extraskeletal myxoid chondrosarcoma. (10478665)
1999
30
Chest wall parachordoma. (10609912)
1999
31
Parachordoma: a rare sarcoma with clonal chromosomal changes. (9530345)
1998
32
Cytogenetic analysis of a parachordoma. (9689924)
1998
33
Cutaneous parachordoma. A light microscopic and immunohistochemical report of two cases and review of the literature. (9696295)
1998
34
Parachordoma: a clinicopathologic and immunohistochemical study of four cases of an unusual soft tissue neoplasm. (9869820)
1997
35
Parachordoma. A case report of a very rare soft tissue tumor. (8950765)
1996
36
Parachordoma of the sacrococcygeal region--a neuroepithelial tumor. (8605741)
1995
37
Parachordoma--a clinicopathologic, immunohistochemical, electron microscopic, flow cytometric, and cytogenetic study. (8542507)
1995
38
Parachordoma of the buttock: an immunohistochemical case study and review. (7530308)
1994
39
Parachordoma. (8030773)
1994
40
Parachordoma. (8191635)
1994
41
Parachordoma: an ultrastructural and immunohistochemical study. (8493780)
1993
42
Parachordoma: a new clinicopathologic entity. (907973)
1977

Variations for Parachordoma

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Expression for genes affiliated with Parachordoma

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Parachordoma

Search GEO for disease gene expression data for Parachordoma.

Pathways for genes affiliated with Parachordoma

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50PathCards, 38NCBI BioSystems Database, 55Reactome
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Pathways related to Parachordoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.6MYH11, DES

Compounds for genes affiliated with Parachordoma

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45Novoseek, 11DrugBank, 51PharmGKB, 24HMDB, 29IUPHAR, 61Tocris Bioscience
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Compounds related to Parachordoma according to GeneCards/GeneDecks:

(show all 38)
idCompoundScoreTop Affiliating Genes
1eosin4510.0S100B, MUC1
2orcein4510.0DES, S100B
3indium459.9CEACAM3, MUC1
43-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide459.8S100B, DES
5metronidazole45 1110.7MUC1, CEACAM3
6s 100459.7DES, MUC1, S100B
7dtpa459.7CEACAM3, MUC1
8ethanol45 51 24 1112.5S100B, MUC1, DES
9adriamycin459.4CEACAM3, MUC1, DES
10gold459.4DES, MUC1, CEACAM3
11ccl445 2910.4S100B, DES
12acth459.3S100B, CEACAM3, MUC1
13reticulin459.2DES, MUC1, S100B, KRT7
14hyaluronic acid45 2410.2KRT20, MUC1, DES
15methotrexate51 45 1111.2MUC1, CEACAM3, KRT7
16glycogen45 2410.2DES, MUC1, S100B, KRT7
17lactate459.1S100B, CEACAM3, DES
18thymidine45 2410.0DES, MUC1, CEACAM3, S100B
19creatinine459.0DES, MUC1, CEACAM3, S100B
20sialic acid459.0KRT7, S100B, CEACAM3, MUC1
21oxygen45 249.8DES, MUC1, CEACAM3, S100B
22retinoic acid45 249.7DES, MYH11, MUC1, S100B, KRT7
23iron45 249.7KRT20, KRT7, S100B, DES
24doxorubicin45 51 1110.7KRT20, CEACAM3, DES
25nitric oxide45 24 1110.6DES, MYH11, MUC1, CEACAM3, S100B
26glucose458.5KRT7, S100B, CEACAM3, MUC1, DES
27streptavidin458.5KRT20, KRT7, CEACAM3, DES
28formaldehyde45 249.4DES, MUC1, S100B, KRT7, KRT20
29testosterone45 61 24 1111.4DES, MUC1, S100B, KRT7, KRT20
30calcium45 51 24 1111.1DES, MUC1, CEACAM3, S100B, S100P
31b 723457.8MUC1, DES, CEACAM3, S100B, KRT20, KRT7
32mucicarmine457.8KRT20, KRT7, S100B, CEACAM3, MUC1, DES
33tyrosine457.7DES, MUC1, CEACAM3, S100B, KRT7, KRT20
34hematoxylin457.3KRT20, KRT7, S100B, CEACAM3, MUC1, MYH11
35paraffin457.3DES, MYH11, MUC1, CEACAM3, S100B, KRT7
36progesterone45 29 61 24 1111.3DES, MYH11, MUC1, CEACAM3, S100B, KRT7
37vegf457.3DES, MYH11, MUC1, CEACAM3, S100B, KRT7
38estrogen457.3DES, MYH11, MUC1, CEACAM3, S100B, KRT7

GO Terms for genes affiliated with Parachordoma

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16Gene Ontology
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Cellular components related to Parachordoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:0058828.5KRT20, KRT7, DES
2cytoplasmGO:0057377.5KRT20, KRT7, S100P, S100B, MUC1, T

Molecular functions related to Parachordoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1calcium-dependent protein bindingGO:0483069.5S100P, S100B
2RNA polymerase II core promoter proximal region sequence-specific DNA bindingGO:0009789.5MUC1, T
3protein bindingGO:0055156.9KRT20, DES, MYH11, MUC1, S100B, S100P

Products for genes affiliated with Parachordoma

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Sources for Parachordoma

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet