MCID: PRC011
MIFTS: 26

Parachordoma malady

Summaries for Parachordoma

Sources:
33MalaCards
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MalaCards: Parachordoma is related to myoepithelioma and chest wall parachordoma. An important gene associated with Parachordoma is T (T, brachyury homolog (mouse)). The compounds eosin and creatinine have been mentioned in the context of this disorder.

Aliases & Classifications for Parachordoma

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 40NCIt, 57SNOMED-CT
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Aliases & Descriptions:

parachordoma 8 10 61


External Ids:

Disease Ontology8 DOID:2647
NCIt40 C6581

Related Diseases for Parachordoma

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Parachordoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 104)
idRelated DiseaseScoreTop Affiliating Genes
1myoepithelioma30.2S100B
2chest wall parachordoma10.4
3extraskeletal myxoid chondrosarcoma10.0
4thymoma10.0CEACAM3
5papilloma10.0KRT20
6bladder carcinoma10.0KRT20
7angiosarcoma10.0MUC1
8paraganglioma10.0S100B
9angiomyolipoma10.0DES
10prostate cancer10.0CEACAM3
11glomus tumor10.0DES
12fibromatosis10.0DES
13inverted papilloma10.0KRT20
14colon cancer10.0KRT20, CEACAM3
15kidney cancer10.0KRT7
16metanephric adenoma10.0KRT7
17cystadenocarcinoma10.0CEACAM3, MUC1
18mixed cell type cancer10.0KRT7
19synovial sarcoma10.0KRT7
20renal oncocytoma10.0KRT7
21teratoma10.0KRT7
22nephrogenic adenoma10.0KRT7
23fibrous meningioma10.0S100B, MUC1
24hemangioblastoma10.0MUC1, S100B
25perineurioma10.0MUC1, S100B
26ependymoma10.0MUC1, S100B
27rectum cancer10.0CEACAM3, KRT20
28merkel cell carcinoma10.0KRT20, MUC1
29neurofibroma10.0S100B, MUC1
30choroid plexus papilloma10.0MUC1, S100B
31anaplastic ependymoma10.0MUC1, S100B
32malignant pleural mesothelioma10.0CEACAM3, MUC1
33rhabdoid tumor10.0DES, MUC1
34sertoli cell tumor10.0MUC1, DES
35mesenchymal chondrosarcoma10.0MUC1, DES
36desmoplastic small round cell tumor10.0MUC1, DES
37spindle cell carcinoma10.0DES, MUC1
38meningioma10.0S100B, MUC1
39granular cell tumor10.0DES, S100B
40malignant peripheral nerve sheath tumor10.0S100B, MUC1
41cystadenoma10.0CEACAM3, KRT7
42leiomyoma10.0DES, S100B
43pulmonary alveolar proteinosis10.0MUC1, CEACAM3
44endometrial carcinoma10.0KRT7, KRT20
45cutaneous fibrous histiocytoma10.0DES, S100B
46sertoli-leydig cell tumor10.0MUC1, KRT7
47fibrous histiocytoma10.0S100B, DES
48bladder adenocarcinoma10.0KRT20, KRT7
49ovarian brenner tumor10.0KRT20, KRT7
50signet ring cell adenocarcinoma10.0KRT20, KRT7

Graphical network of the top 20 diseases related to Parachordoma:



Diseases related to parachordoma

Clinical Features for Parachordoma

Drugs & Therapeutics for Parachordoma

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Parachordoma

Drug clinical trials:

Search ClinicalTrials for Parachordoma

Search NIH Clinical Center for Parachordoma

Search CenterWatch for Parachordoma

Genetic Tests for Parachordoma

Anatomical Context for Parachordoma

Animal Models for Parachordoma or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Parachordoma

Sources:
51PubMed
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Articles related to Parachordoma:

(show all 42)
idTitleAuthorsYear
1
A case of parachordoma on the chest wall and literature review. (24135242)
2013
2
Parachordoma/myoepithelioma. (22618759)
2013
3
Parachordoma of soft tissues of the arm: a very rare tumour. (24083043)
2013
4
Huge pelvic parachordoma: fine needle aspiration cytology and histological differential diagnosis. (23372917)
2012
5
Clinical and radiological presentations of pelvic parachordoma. (22532921)
2012
6
Intraneural parachordoma of the arm with regional metastases. (21499979)
2011
7
Presacral parachordoma causing intestinal obstruction in a patient with renal failure: Report of a case. (21922364)
2011
8
Axial chordoma and parachordoma (soft tissue chordoma): two of a kind: report of two cases with primary diagnosis on fine-needle cytology samples. (20730897)
2011
9
Parachordoma: a recurrent case and review of the literature. (21630208)
2011
10
Fine needle aspiration appearance of parachordoma. (20306999)
2010
11
Parachordoma of skull. (20303594)
2010
12
Metastatic parachordoma. (19208078)
2009
13
Pulmonary metastases from parachordoma. (19632372)
2009
14
Parachordoma: a very rare tumour of the hand. (20067931)
2009
15
Possible parachordoma in a dog. (19802045)
2009
16
Case report: parachordoma of soft tissues of the arm. (18219545)
2008
17
Brachyury expression in extra-axial skeletal and soft tissue chordomas: a marker that distinguishes chordoma from mixed tumor/myoepithelioma/parachordoma in soft tissue. (18301055)
2008
18
Parachordoma or myoepithelion?: a case report of a rare soft tissue tumor. (17295651)
2007
19
Parachordoma of the gastric serosa: report of a myxoid mimicry in an unusual location. (17652546)
2007
20
Fatal parachordoma. (17260126)
2007
21
Retroperitoneal parachordoma in a patient with a history of recurrent pain. (15863385)
2005
22
Parachordoma is not distinguishable from axial chordoma using immunohistochemistry. (15086843)
2004
23
Parachordoma of tibia--a case report. (15025303)
2003
24
Parachordoma or chordoma periphericum? Case report of a tumor of the thoracic wall. (12827710)
2003
25
Parachordoma with multiple metastases. (12886158)
2003
26
Parachordoma: a case report. (11504379)
2001
27
Parachordoma exists--but what is it? (10809219)
2000
28
Parachordoma of the tibia: report of a rare case. (10782472)
2000
29
Parachordoma is immunohistochemically and cytogenetically distinct from axial chordoma and extraskeletal myxoid chondrosarcoma. (10478665)
1999
30
Chest wall parachordoma. (10609912)
1999
31
Parachordoma: a rare sarcoma with clonal chromosomal changes. (9530345)
1998
32
Cytogenetic analysis of a parachordoma. (9689924)
1998
33
Cutaneous parachordoma. A light microscopic and immunohistochemical report of two cases and review of the literature. (9696295)
1998
34
Parachordoma: a clinicopathologic and immunohistochemical study of four cases of an unusual soft tissue neoplasm. (9869820)
1997
35
Parachordoma. A case report of a very rare soft tissue tumor. (8950765)
1996
36
Parachordoma of the sacrococcygeal region--a neuroepithelial tumor. (8605741)
1995
37
Parachordoma--a clinicopathologic, immunohistochemical, electron microscopic, flow cytometric, and cytogenetic study. (8542507)
1995
38
Parachordoma of the buttock: an immunohistochemical case study and review. (7530308)
1994
39
Parachordoma. (8030773)
1994
40
Parachordoma. (8191635)
1994
41
Parachordoma: an ultrastructural and immunohistochemical study. (8493780)
1993
42
Parachordoma: a new clinicopathologic entity. (907973)
1977

Genetic Variations for Parachordoma

Expression for genes affiliated with Parachordoma

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Parachordoma

Search GEO for disease gene expression data for Parachordoma.

Pathways for genes affiliated with Parachordoma

Compounds for genes affiliated with Parachordoma

Sources:
45Novoseek, 11DrugBank, 24HMDB, 50PharmGKB, 60Tocris Bioscience, 29IUPHAR
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Compounds related to Parachordoma according to GeneCards/GeneDecks:

(show all 32)
idCompoundScoreTop Affiliating Genes
1eosin4510.1S100B, MUC1
2creatinine4510.0CEACAM3
3orcein4510.0DES, S100B
4indium459.8CEACAM3, MUC1
5s 100459.7MUC1, DES, S100B
63-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide459.7DES, S100B
7metronidazole45 1110.6MUC1, CEACAM3
8dtpa459.5CEACAM3, MUC1
9adriamycin459.3CEACAM3, MUC1, DES
10gold459.3DES, MUC1, CEACAM3
11glucose459.2MUC1, KRT7, CEACAM3
12reticulin459.2S100B, DES, MUC1, KRT7
13acth459.2CEACAM3, MUC1, S100B
14glycogen45 2410.1KRT7, MUC1, DES, S100B
15hyaluronic acid45 2410.0KRT20, MUC1, DES
16ethanol45 50 11 2412.0MUC1, DES, S100B
17sialic acid459.0S100B, MUC1, KRT7, CEACAM3
18thymidine45 249.9CEACAM3, MUC1, DES, S100B
19methotrexate45 50 1110.9MUC1, KRT7, CEACAM3
20retinoic acid45 249.6S100B, DES, MYH11, MUC1, KRT7
21iron45 249.6KRT20, KRT7, DES, S100B
22nitric oxide45 11 2410.6S100B, DES, MYH11, MUC1, CEACAM3
23streptavidin458.5CEACAM3, KRT20, KRT7, DES
24formaldehyde45 249.4S100B, DES, MUC1, KRT7, KRT20
25testosterone45 60 11 2411.3S100B, DES, MUC1, KRT7, KRT20
26mucicarmine457.8S100B, DES, MUC1, KRT7, KRT20, CEACAM3
27b 723457.8S100B, DES, MUC1, KRT7, KRT20, CEACAM3
28tyrosine457.7CEACAM3, KRT20, KRT7, MUC1, DES, S100B
29hematoxylin457.3CEACAM3, S100B, DES, MYH11, MUC1, KRT7
30paraffin457.3S100B, DES, MYH11, MUC1, KRT7, KRT20
31progesterone45 60 29 11 2411.3S100B, DES, MYH11, MUC1, KRT7, KRT20
32vegf457.3S100B, DES, MYH11, MUC1, KRT7, KRT20

GO Terms for genes affiliated with Parachordoma

Sources:
16Gene Ontology
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Cellular components related to Parachordoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:0058828.7KRT20, KRT7, DES

Molecular functions related to Parachordoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1calcium-dependent protein bindingGO:0483069.6S100B, S100P
2RNA polymerase II core promoter proximal region sequence-specific DNA bindingGO:0009789.5MUC1, T

Products for genes affiliated with Parachordoma

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Sources for Parachordoma

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet