MCID: PRC011
MIFTS: 31

Parachordoma malady

Summaries for Parachordoma

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32MalaCards
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MalaCards: Parachordoma is related to chordoma and myoepithelioma. An important gene associated with Parachordoma is T (T, brachyury homolog (mouse)). The compounds eosin and creatinine have been mentioned in the context of this disorder.

Aliases & Classifications for Parachordoma

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8Disease Ontology, 10DISEASES, 60UMLS, 39NCIt, 56SNOMED-CT
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Aliases & Descriptions:

parachordoma 8 10 60


External Ids:

Disease Ontology8 DOID:2647
NCIt39 C6581

Related Diseases for Parachordoma

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Parachordoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 106)
idRelated DiseaseScoreTop Affiliating Genes
1chordoma30.4CEACAM3, KRT7, MUC1, DES, S100B
2myoepithelioma30.2S100B
3sarcoma29.9MUC1, DES, S100B
4chondrosarcoma29.9S100B, DES, MUC1, CEACAM3
5chest wall parachordoma10.4
6thymoma10.0CEACAM3
7papilloma10.0KRT20
8bladder carcinoma10.0KRT20
9angiosarcoma10.0MUC1
10paraganglioma10.0S100B
11angiomyolipoma10.0DES
12prostate cancer10.0CEACAM3
13glomus tumor10.0DES
14fibromatosis10.0DES
15colon cancer10.0CEACAM3, KRT20
16inverted papilloma10.0KRT20
17kidney cancer10.0KRT7
18metanephric adenoma10.0KRT7
19cystadenocarcinoma10.0MUC1, CEACAM3
20mixed cell type cancer10.0KRT7
21synovial sarcoma10.0KRT7
22renal oncocytoma10.0KRT7
23teratoma10.0KRT7
24nephrogenic adenoma10.0KRT7
25fibrous meningioma10.0MUC1, S100B
26hemangioblastoma10.0MUC1, S100B
27perineurioma10.0S100B, MUC1
28ependymoma10.0MUC1, S100B
29rectal neoplasm10.0CEACAM3, KRT20
30merkel cell carcinoma10.0MUC1, KRT20
31neurofibroma10.0MUC1, S100B
32choroid plexus papilloma10.0MUC1, S100B
33anaplastic ependymoma10.0S100B, MUC1
34malignant pleural mesothelioma10.0MUC1, CEACAM3
35rhabdoid tumor10.0DES, MUC1
36sertoli cell tumor10.0DES, MUC1
37desmoplastic small round cell tumor10.0DES, MUC1
38mesenchymal chondrosarcoma10.0DES, MUC1
39spindle cell carcinoma10.0MUC1, DES
40meningioma10.0MUC1, S100B
41granular cell tumor10.0S100B, DES
42pulmonary alveolar proteinosis10.0MUC1, CEACAM3
43cystadenoma10.0CEACAM3, KRT7
44malignant peripheral nerve sheath tumor10.0MUC1, S100B
45leiomyoma10.0DES, S100B
46endometrial carcinoma10.0KRT20, KRT7
47cutaneous fibrous histiocytoma10.0S100B, DES
48sertoli-leydig cell tumor10.0KRT7, MUC1
49fibrous histiocytoma10.0DES, S100B
50bladder adenocarcinoma10.0KRT7, KRT20

Graphical network of the top 20 diseases related to Parachordoma:



Diseases related to parachordoma

Clinical Features for Parachordoma

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Drugs & Therapeutics for Parachordoma

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Genetic Tests for Parachordoma

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Anatomical Context for Parachordoma

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Animal Models for Parachordoma or affiliated genes

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Publications for Parachordoma

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50PubMed
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Articles related to Parachordoma:

(show all 42)
idTitleAuthorsYear
1
A case of parachordoma on the chest wall and literature review. (24135242)
2013
2
Parachordoma/myoepithelioma. (22618759)
2013
3
Parachordoma of soft tissues of the arm: a very rare tumour. (24083043)
2013
4
Huge pelvic parachordoma: fine needle aspiration cytology and histological differential diagnosis. (23372917)
2012
5
Clinical and radiological presentations of pelvic parachordoma. (22532921)
2012
6
Intraneural parachordoma of the arm with regional metastases. (21499979)
2011
7
Presacral parachordoma causing intestinal obstruction in a patient with renal failure: Report of a case. (21922364)
2011
8
Axial chordoma and parachordoma (soft tissue chordoma): two of a kind: report of two cases with primary diagnosis on fine-needle cytology samples. (20730897)
2011
9
Parachordoma: a recurrent case and review of the literature. (21630208)
2011
10
Fine needle aspiration appearance of parachordoma. (20306999)
2010
11
Parachordoma of skull. (20303594)
2010
12
Metastatic parachordoma. (19208078)
2009
13
Pulmonary metastases from parachordoma. (19632372)
2009
14
Parachordoma: a very rare tumour of the hand. (20067931)
2009
15
Possible parachordoma in a dog. (19802045)
2009
16
Case report: parachordoma of soft tissues of the arm. (18219545)
2008
17
Brachyury expression in extra-axial skeletal and soft tissue chordomas: a marker that distinguishes chordoma from mixed tumor/myoepithelioma/parachordoma in soft tissue. (18301055)
2008
18
Parachordoma or myoepithelion?: a case report of a rare soft tissue tumor. (17295651)
2007
19
Parachordoma of the gastric serosa: report of a myxoid mimicry in an unusual location. (17652546)
2007
20
Fatal parachordoma. (17260126)
2007
21
Retroperitoneal parachordoma in a patient with a history of recurrent pain. (15863385)
2005
22
Parachordoma is not distinguishable from axial chordoma using immunohistochemistry. (15086843)
2004
23
Parachordoma of tibia--a case report. (15025303)
2003
24
Parachordoma or chordoma periphericum? Case report of a tumor of the thoracic wall. (12827710)
2003
25
Parachordoma with multiple metastases. (12886158)
2003
26
Parachordoma: a case report. (11504379)
2001
27
Parachordoma exists--but what is it? (10809219)
2000
28
Parachordoma of the tibia: report of a rare case. (10782472)
2000
29
Parachordoma is immunohistochemically and cytogenetically distinct from axial chordoma and extraskeletal myxoid chondrosarcoma. (10478665)
1999
30
Chest wall parachordoma. (10609912)
1999
31
Parachordoma: a rare sarcoma with clonal chromosomal changes. (9530345)
1998
32
Cytogenetic analysis of a parachordoma. (9689924)
1998
33
Cutaneous parachordoma. A light microscopic and immunohistochemical report of two cases and review of the literature. (9696295)
1998
34
Parachordoma: a clinicopathologic and immunohistochemical study of four cases of an unusual soft tissue neoplasm. (9869820)
1997
35
Parachordoma. A case report of a very rare soft tissue tumor. (8950765)
1996
36
Parachordoma of the sacrococcygeal region--a neuroepithelial tumor. (8605741)
1995
37
Parachordoma--a clinicopathologic, immunohistochemical, electron microscopic, flow cytometric, and cytogenetic study. (8542507)
1995
38
Parachordoma of the buttock: an immunohistochemical case study and review. (7530308)
1994
39
Parachordoma. (8030773)
1994
40
Parachordoma. (8191635)
1994
41
Parachordoma: an ultrastructural and immunohistochemical study. (8493780)
1993
42
Parachordoma: a new clinicopathologic entity. (907973)
1977

Genetic Variations for Parachordoma

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Expression for genes affiliated with Parachordoma

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Parachordoma

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Pathways for genes affiliated with Parachordoma

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Compounds for genes affiliated with Parachordoma

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44Novoseek, 11DrugBank, 24HMDB, 49PharmGKB, 59Tocris Bioscience, 28IUPHAR
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Compounds related to Parachordoma according to GeneCards/GeneDecks:

(show all 32)
idCompoundScoreTop Affiliating Genes
1eosin4410.1S100B, MUC1
2creatinine4410.0CEACAM3
3orcein4410.0DES, S100B
4indium449.8CEACAM3, MUC1
5s 100449.7MUC1, DES, S100B
63-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide449.7DES, S100B
7metronidazole44 1110.6MUC1, CEACAM3
8dtpa449.5CEACAM3, MUC1
9adriamycin449.3CEACAM3, MUC1, DES
10gold449.3DES, MUC1, CEACAM3
11glucose449.2MUC1, KRT7, CEACAM3
12reticulin449.2S100B, DES, MUC1, KRT7
13acth449.2CEACAM3, MUC1, S100B
14glycogen44 2410.1KRT7, MUC1, DES, S100B
15hyaluronic acid44 2410.0KRT20, MUC1, DES
16ethanol44 49 11 2412.0MUC1, DES, S100B
17sialic acid449.0S100B, MUC1, KRT7, CEACAM3
18thymidine44 249.9CEACAM3, MUC1, DES, S100B
19methotrexate44 49 1110.9MUC1, KRT7, CEACAM3
20retinoic acid44 249.6S100B, DES, MYH11, MUC1, KRT7
21iron44 249.6KRT20, KRT7, DES, S100B
22nitric oxide44 11 2410.6S100B, DES, MYH11, MUC1, CEACAM3
23streptavidin448.5CEACAM3, KRT20, KRT7, DES
24formaldehyde44 249.4S100B, DES, MUC1, KRT7, KRT20
25testosterone44 59 11 2411.3S100B, DES, MUC1, KRT7, KRT20
26mucicarmine447.8S100B, DES, MUC1, KRT7, KRT20, CEACAM3
27b 723447.8S100B, DES, MUC1, KRT7, KRT20, CEACAM3
28tyrosine447.7CEACAM3, KRT20, KRT7, MUC1, DES, S100B
29hematoxylin447.3CEACAM3, S100B, DES, MYH11, MUC1, KRT7
30paraffin447.3S100B, DES, MYH11, MUC1, KRT7, KRT20
31progesterone44 59 28 11 2411.3S100B, DES, MYH11, MUC1, KRT7, KRT20
32vegf447.3S100B, DES, MYH11, MUC1, KRT7, KRT20

GO Terms for genes affiliated with Parachordoma

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16Gene Ontology
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Cellular components related to Parachordoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:0058828.7KRT20, KRT7, DES

Molecular functions related to Parachordoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1calcium-dependent protein bindingGO:0483069.6S100B, S100P
2RNA polymerase II core promoter proximal region sequence-specific DNA bindingGO:0009789.5MUC1, T

Products for genes affiliated with Parachordoma

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Sources for Parachordoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet