PIV3
MCID: PRN029
MIFTS: 48

Parainfluenza Virus Type 3 (PIV3) malady

Rare diseases category

Summaries for Parainfluenza Virus Type 3

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34MalaCards
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MalaCards: Parainfluenza Virus Type 3, also known as human parainfluenza virus type 3, is related to measles and influenza. An important gene associated with Parainfluenza Virus Type 3 is NEU1 (sialidase 1 (lysosomal sialidase)), and among its related pathways are Cytokines and Inflammatory Response and Immune response MIF mediated glucocorticoid regulation. The compounds rebif and avonex have been mentioned in the context of this disorder. Affiliated tissues include lung, t cells and bone marrow, and related mouse phenotypes are tumorigenesis and liver/biliary system.

Aliases & Classifications for Parainfluenza Virus Type 3

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44NIH Rare Diseases
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


Aliases & Descriptions:

parainfluenza virus type 3 44
human parainfluenza virus type 3 44
piv3 44


Related Diseases for Parainfluenza Virus Type 3

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18GeneCards, 19GeneDecks
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Diseases related to Parainfluenza Virus Type 3 via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 89)
idRelated DiseaseScoreTop Affiliating Genes
1measles30.7MX1, IFNB1, STAT1, RNPC3
2influenza30.5MX1, EIF2AK2, CRAT, ZNF17, IFIH1, IFNB1
3newcastle disease30.5NEU1, IFNA1, IFNB1
4herpes simplex30.2RNASEL, NEU1, STAT1, IFNA1, IFNB1, CRAT
5pneumonia10.8
6vaccinia10.6
7meningitis10.5
8diarrhea10.4
9hydrocephalus10.4
10pertussis10.4
11fetal parainfluenza virus type 3 syndrome10.4
12urethritis10.3
13bronchiolitis10.3
14meningoencephalitis10.3
15parotitis10.3
16swine influenza10.3
17stevens-johnson syndrome10.3
18aseptic meningitis10.3
19bronchopneumonia10.3
20toxic epidermal necrolysis10.3
21blindness10.3
22venezuelan equine encephalitis10.1FURIN
23chronic inflammatory demyelinating polyradiculoneuropathy10.1IFNB1
24rift valley fever10.1MX1
25hemophagocytic lymphohistiocytosis10.1IFNB1, MX1
26rabies10.1MX1, RNPC3
27dengue disease10.1RNASEL, NEU1, IFNB1
28chronic fatigue syndrome10.1EIF2AK2, RNASEL
29subacute sclerosing panencephalitis10.1MX1, IFNA1
30mumps10.1EIF2AK2, STAT1, NEU1
31dermatomyositis10.1MX1, ICAM1
32thyroiditis10.1IFNA1
33hypothyroidism10.1IFNA1, IFNB1
34myocarditis10.1IFNB1
35immunoglobulin a vasculitis10.1ICAM1, MX1
36acute erythroid leukemia10.0CRAT, IFNB1, STAT1
37congenital stationary night blindness, type 1f10.0IFNA1, IFNB1
38cervical cancer10.0CRAT, IFNB1, STAT1
39hepatitis10.0STAT1, IFNA1, IFNB1
40tropical spastic paraparesis10.0IL2, IFNB1
41allergic asthma10.0IFNB1, STAT1, ICAM1
42down syndrome10.0GAPDH, MX1, NCL
43viral hepatitis10.0MX1, IFNB1, IFNA1, STAT1
44malaria10.0GAPDH, ICAM1, NEU1
45iga glomerulonephritis10.0GAPDH, ICAM1, NEU1
46malignant glioma10.0FURIN, NEU1, STAT1, IFNB1, CRAT
47choriocarcinoma10.0STAT1, CRAT, GAPDH
48lichen planus10.0ICAM1, MX1
49hepatitis d10.0RNPC3, IFNA1, NCL, EIF2AK2
50sezary's disease10.0IL2, IFNA1

Graphical network of the top 20 diseases related to Parainfluenza Virus Type 3:



Diseases related to parainfluenza virus type 3

Symptoms for Parainfluenza Virus Type 3

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Drugs & Therapeutics for Parainfluenza Virus Type 3

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Parainfluenza Virus Type 3

Drug clinical trials:

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Search CenterWatch for Parainfluenza Virus Type 3

Genetic Tests for Parainfluenza Virus Type 3

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Anatomical Context for Parainfluenza Virus Type 3

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34MalaCards
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MalaCards organs/tissues related to Parainfluenza Virus Type 3:

34
Lung, T cells, Bone marrow, Bone, Liver, Testes, Monocytes

Animal Models for Parainfluenza Virus Type 3 or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Parainfluenza Virus Type 3:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.7DDX58, ICAM1, STAT1, IFNB1, IL2, EIF2AK2
2MP:00053708.4DDX58, FURIN, NEU1, STAT1, IL2, GAPDH
3MP:00053847.9DDX58, RNASEL, NEU1, ICAM1, STAT1, IFIH1
4MP:00053857.8FURIN, NEU1, ICAM1, STAT1, IL2, CRAT
5MP:00053787.7FURIN, NEU1, ICAM1, STAT1, IL2, CRAT
6MP:00053877.2NEU1, RNASEL, FURIN, DDX58, PRKCZ, ICAM1
7MP:00107687.0DDX58, FURIN, NEU1, ICAM1, STAT1, IFIH1
8MP:00053767.0ICAM1, PRKCZ, NEU1, DDX58, STAT1, IFNB1
9MP:00053976.7GAPDH, DDX58, FURIN, RNASEL, NEU1, PRKCZ

Publications for Parainfluenza Virus Type 3

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53PubMed
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Articles related to Parainfluenza Virus Type 3:

(show top 50)    (show all 249)
idTitleAuthorsYear
1
Prevalence of antibodies against Parainfluenza virus type 3, Respiratory syncitial virus and bovine Herpesvirus type 1 in sheep from Northern Prefectures of Japan. (24166480)
2013
2
Comparison of differing cytopathic effects in human airway epithelium of parainfluenza virus 5 (W3A), parainfluenza virus type 3, and respiratory syncytial virus. (21986028)
2011
3
Identification of simian agent 10 as human parainfluenza virus type 3 suggests transmission of a human virus to an African monkey. (20881043)
2010
4
Phosphoprotein, P of human parainfluenza virus type 3 prevents self-association of RNA-dependent RNA polymerase, L. (19012944)
2009
5
Evidence for phosphorylation of human parainfluenza virus type 3 C protein: mutant C proteins exhibit variable inhibitory activities in vitro. (19410612)
2009
6
Natural killer cells regulate T-cell proliferation during human parainfluenza virus type 3 infection. (18614637)
2008
7
Inhibition of human parainfluenza virus type 3 infection by novel small molecules. (17964670)
2008
8
Molecular investigations of an outbreak of parainfluenza virus type 3 and respiratory syncytial virus infections in a hematology unit. (17392447)
2007
9
A chimeric alphavirus RNA replicon gene-based vaccine for human parainfluenza virus type 3 induces protective immunity against intranasal virus challenge. (17052811)
2007
10
Roles of human parainfluenza virus type 3 bases 13 to 78 in replication and transcription: identification of an additional replication promoter element and evidence for internal transcription initiation. (16699019)
2006
11
Interferon action against human parainfluenza virus type 3: involvement of a novel antiviral pathway in the inhibition of transcription. (11312354)
2001
12
Human parainfluenza virus type 3 HN-receptor interaction: effect of 4-guanidino-Neu5Ac2en on a neuraminidase-deficient variant. (11462020)
2001
13
A single amino acid substitution in the viral polymerase creates a temperature-sensitive and attenuated recombinant bovine parainfluenza virus type 3. (11601905)
2001
14
Antibody responses to bovine parainfluenza virus type 3 (PIV3) vaccination and human PIV3 infection in young infants. (11509996)
2001
15
Role of NH(2)- and COOH-terminal domains of the P protein of human parainfluenza virus type 3 in transcription and replication. (10846069)
2000
16
Sequence determination and molecular analysis of two strains of bovine parainfluenza virus type 3 that are attenuated for primates. (10872880)
2000
17
Specific phosphorylated forms of glyceraldehyde 3-phosphate dehydrogenase associate with human parainfluenza virus type 3 and inhibit viral transcription in vitro. (10729139)
2000
18
Precise mapping of the replication and transcription promoters of human parainfluenza virus type 3. (10725212)
2000
19
Long nucleotide insertions between the HN and L protein coding regions of human parainfluenza virus type 3 yield viruses with temperature-sensitive and attenuation phenotypes. (10873765)
2000
20
Mutations in the C, D, and V open reading frames of human parainfluenza virus type 3 attenuate replication in rodents and primates. (10497117)
1999
21
Immune responses and protection induced by DNA vaccines encoding bovine parainfluenza virus type 3 glycoproteins. (10405354)
1999
22
Three amino acid substitutions in the L protein of the human parainfluenza virus type 3 cp45 live attenuated vaccine candidate contribute to its temperature-sensitive and attenuation phenotypes. (9499025)
1998
23
Interaction of human parainfluenza virus type 3 with the host cell surface. (9380464)
1997
24
Current status of respiratory syncytial virus (RSV) and parainfluenza virus type 3 (PIV3) vaccine development: memorandum from a joint WHO/NIAID meeting. (9342889)
1997
25
Rescue of Sendai virus cDNA templates with cDNA clones expressing parainfluenza virus type 3 N, P and L proteins. (8887479)
1996
26
Some virological and pathomorphological aspects of the respiratory system in the experimental infection with respiratory syncytial virus associated with influenza virus, parainfluenza virus type 3 and adenovirus in the mouse. (9495783)
1996
27
Human parainfluenza virus type 3: analysis of the cytoplasmic tail and transmembrane anchor of the hemagglutinin-neuraminidase protein in promoting cell fusion. (7653094)
1995
28
Sequence variation in the haemagglutinin-neuraminidase gene of human parainfluenza virus type 3 isolates in the UK. (7781737)
1995
29
Proteolytic cleavage of wild type and mutants of the F protein of human parainfluenza virus type 3 by two subtilisin-like endoproteases, furin and Kex2. (8139055)
1994
30
A prototype recombinant vaccine against respiratory syncytial virus and parainfluenza virus type 3. (7765021)
1994
31
Parainfluenza virus type 3 and pertussis syndrome. (8244477)
1993
32
Parainfluenza virus type 3 (PIV3)-specific and non-virus-specific delayed type hypersensitivity responses in cotton rats given different PIV3 antigen preparations. (8383384)
1993
33
Isolation of parainfluenza virus type 3 from cerebrospinal fluid. (1316416)
1992
34
RNA editing in the phosphoprotein gene of the human parainfluenza virus type 3. (1310183)
1992
35
Fusion properties of cells persistently infected with human parainfluenza virus type 3: participation of hemagglutinin-neuraminidase in membrane fusion. (1851852)
1991
36
Defective interfering particles of human parainfluenza virus type 3 are associated with persistent infection in cell culture. (1649512)
1991
37
Parainfluenza virus type 3: surveillance. (1669815)
1991
38
Human parainfluenza virus type 3 transcription in vitro: role of cellular actin in mRNA synthesis. (1851877)
1991
39
Outbreak of parainfluenza virus type 3 in a neonatal nursery. (2153949)
1990
40
Antibodies to parainfluenza virus type 3 in Minnesota swine. (2849496)
1988
41
Protection of weanling hamsters from experimental infection with wild-type parainfluenza virus type 3 (para 3) by cold-adapted mutants of para 3. (3005486)
1986
42
Parainfluenza virus type 3 in pigs. (3024379)
1986
43
The effect of parainfluenza virus type 3 on the phagocytic cell response of the ovine lung to Pasteurella haemolytica. (3010545)
1986
44
Conserved structures among the nucleocapsid proteins of the paramyxoviridae: complete nucleotide sequence of human parainfluenza virus type 3 NP mRNA. (3012866)
1986
45
Properties of temperature-sensitive mutants of parainfluenza virus type 3 selected during the course of persistent infection. (2986583)
1985
46
Evidence of a T-cell-mediated cytotoxic response to parainfluenza virus type 3 pneumonia in hamsters. (6278144)
1982
47
The effect of vaccination of lambs with live parainfluenza virus type 3 on pneumonia produced by parainfluenza virus type 3 and Pasteurella haemolytica. (6258113)
1980
48
Pulmonary cell-mediated cytotoxicity in hamsters with parainfluenza virus type 3 pneumonia. (223482)
1979
49
Respiratory infection of lambs with an ovine strain parainfluenza virus type 3. (4309242)
1969
50
Cytopathic effects of parainfluenza virus Type 3 in organ cultures of human respiratory tract tissue. (4295104)
1968

Variations for Parainfluenza Virus Type 3

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Expression for genes affiliated with Parainfluenza Virus Type 3

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Parainfluenza Virus Type 3

Search GEO for disease gene expression data for Parainfluenza Virus Type 3.

Pathways for genes affiliated with Parainfluenza Virus Type 3

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Sources:
51PathCards, 39NCBI BioSystems Database, 61Thomson Reuters, 31KEGG, 54QIAGEN, 55R&D Systems, 56Reactome
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Pathways related to Parainfluenza Virus Type 3 according to GeneCards/GeneDecks:

(show all 22)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.9IFNB1, IL2
29.9IL2, ICAM1
39.6IL2, STAT1, ICAM1
49.5STAT1, IFNA1, IFNB1
59.5STAT1, IFNA1, IFNB1
69.4IL2, IFNB1, IFNA1
7
Show member pathways
IFN-gamma pathway39
9.4EIF2AK2, STAT1, ICAM1
8
Show member pathways
IL23-mediated signaling events39
Immune response IL 10 signaling pathway61
Angiopoietin receptor Tie2-mediated signaling39
Development PDGF signaling via STATs and NF kB61
Development Angiopoietin Tie2 signaling61
9.4STAT1, IL2, EIF2AK2
9
Show member pathways
IL-9 Signaling Pathway39
Development Thrombopoietin regulated cell processes61
IL-7 Signaling Pathway39
Immune response IL 9 signaling pathway61
9.2IL2, STAT1, PRKCZ
10
Show member pathways
9.2IFIH1, IFNB1, IFNA1, DDX58
11
Show member pathways
9.2DDX58, IFNA1, IFNB1, IFIH1
129.2ICAM1, STAT1, IFNB1, EIF2AK2
13
Show member pathways
Type III interferon signaling39
9.1STAT1, IFNA1, IFNB1, IL2
14
Show member pathways
Immune response CD16 signaling in NK cells61
9.1ICAM1, IFNA1, IFNB1, IL2
15
Show member pathways
9.0RNASEL, STAT1, IFNA1, IFNB1, MX1
168.8PRKCZ, IFNA1, IFNB1, IL2
17
Show member pathways
Toll-like receptor signaling pathway39
Regulation of toll-like receptor signaling pathway39
8.6DDX58, STAT1, IFNA1, IFNB1, IFIH1, IL2
18
Show member pathways
Transcription Receptor mediated HIF regulation61
Development CNTF receptor signaling61
Class IB PI3K non-lipid kinase events39
ErbB2/ErbB3 signaling events39
Development Growth hormone signaling via PI3K AKT and MAPK cascades61
Translation Regulation activity of EIF261
Regulation of lipid metabolism Insulin signaling generic cascades61
Transcription PPAR Pathway61
Cell adhesion PLAU signaling61
Translation Regulation activity of EIF4F61
8.6EIF2AK2, NCL, STAT1, PRKCZ
19
Show member pathways
8.5PRKCZ, STAT1, IFNA1, IFNB1, IL2
208.5DDX58, RNASEL, STAT1, IFNA1, IFNB1, EIF2AK2
21
Show member pathways
7.6DDX58, RNASEL, ICAM1, STAT1, IFNA1, IFNB1
22
Show member pathways
7.1MX1, DDX58, FURIN, RNASEL, ICAM1, STAT1

Compounds for genes affiliated with Parainfluenza Virus Type 3

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Sources:
46Novoseek, 12DrugBank, 62Tocris Bioscience, 30IUPHAR, 52PharmGKB, 3BitterDB, 25HMDB
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Compounds related to Parainfluenza Virus Type 3 according to GeneCards/GeneDecks:

(show top 50)    (show all 130)
idCompoundScoreTop Affiliating Genes
1rebif469.9IFNB1, IFNA1, MX1
2avonex469.9MX1, IFNA1, IFNB1
3betaseron469.9MX1, IFNB1, IFNA1
4glatiramer acetate46 1210.7IFNB1, IFNA1, IL2
5poly c469.7EIF2AK2, RNPC3, IFNB1
6acyclovir46 1210.7IFNB1, NEU1, IFNA1
7levamisole46 1210.7NEU1, IL2, IFNA1
8dacarbazine46 1210.6IFNA1, IL2, IFNB1
9imiquimod46 62 30 1212.6MX1, IFNB1, IFNA1, STAT1
10neomycin469.5CRAT, RNPC3, IFNB1, IL2
11zidovudine46 52 1211.5IL2, IFNB1, NEU1, IFNA1
12indoleamine469.5STAT1, IFNA1, IFNB1
13tetracycline46 1210.4IFNB1, FURIN, EIF2AK2, CRAT
14inosine monophosphate469.3IFNB1, EIF2AK2, IFNA1, STAT1
15temozolomide46 1210.3IFNA1, IFNB1, IL2
16neopterin469.3IFNA1, IL2, MX1, IFNB1, ICAM1
17chloroquine46 3 52 30 1213.2IFNB1, IL2, EIF2AK2, IFNA1
18rrna469.0RNPC3, RNASEL, NCL, GAPDH
19polyethylene glycol468.9GAPDH, NEU1, ICAM1, IFNA1
20poly(i-c)468.9IFNA1, STAT1, DDX58, EIF2AK2, IFNB1, MX1
21biotin46 25 1210.8STAT1, IL2, GAPDH, RNPC3
22ifn-alpha468.6RNASEL, STAT1, IFNA1, IFNB1, MX1, EIF2AK2
23retinoid468.6IFNA1, IFNB1, GAPDH, CRAT, STAT1
24pge2468.5GAPDH, ICAM1, IFNB1, STAT1, IL2, CRAT
25h2o2468.4STAT1, GAPDH, IFNB1, ICAM1, NEU1, CRAT
26tamoxifen46 52 30 1211.4IFNA1, IL2, GAPDH, CRAT, IFNB1
27dexamethasone46 52 30 1211.4STAT1, IFNA1, IFNB1, IL2, CRAT, ICAM1
28ribavirin46 52 1210.4IFNA1, IFNB1, MX1, STAT1, NEU1, RNASEL
29arginine468.4CRAT, EIF2AK2, NCL, STAT1, RNPC3, RNASEL
30adenine46 25 1210.3GAPDH, RNPC3, RNASEL, EIF2AK2, IFNB1, CRAT
31heparin46 30 25 1211.3GAPDH, NEU1, FURIN, IFNB1, NCL, EIF2AK2
32cisplatin46 52 62 1211.3IFNA1, STAT1, GAPDH, IFNB1, CRAT, IL2
33rantes468.2MX1, EIF2AK2, IFNB1, IFNA1, STAT1, ICAM1
342,5-oligoadenylate468.2CRAT, IL2, IFNB1, IFNA1, STAT1, RNASEL
35polyinosinic-polycytidylic acid468.2EIF2AK2, IL2, IFIH1, IFNB1, STAT1, CRAT
36adenylate468.1IFNB1, RNPC3, RNASEL, FURIN, GAPDH, NCL
37estrogen468.1GAPDH, NCL, CRAT, NEU1, STAT1, IFNB1
38aspartate468.1FURIN, IFNA1, EIF2AK2, IFNB1, CRAT, GAPDH
39rapamycin468.0PRKCZ, STAT1, IFNA1, IL2, GAPDH
40ly294002467.9PRKCZ, ICAM1, STAT1, IFNB1, GAPDH
41nitric oxide46 25 129.7STAT1, ICAM1, GAPDH, EIF2AK2, RNASEL, PRKCZ
42cyclosporin a46 30 629.6GAPDH, IL2, IFNA1, STAT1, ICAM1, RNPC3
43tyrosine467.6EIF2AK2, NCL, IL2, IFNB1, IFNA1, STAT1
44oligonucleotide467.6STAT1, RNASEL, RNPC3, IFNB1, CRAT, NCL
45actinomycin d467.6ICAM1, STAT1, IL2, IFNA1, IFNB1, GAPDH
46atp46 308.5MX1, RNASEL, RNPC3, STAT1, CRAT, NCL
47vegf467.4CRAT, IL2, GAPDH, IFNB1, IFNA1, STAT1
48cycloheximide466.6CRAT, IL2, IFNB1, IFNA1, STAT1, ICAM1
49retinoic acid46 257.1IFIH1, IFNA1, DDX58, NEU1, PRKCZ, NCL
50serine465.6FURIN, NEU1, PRKCZ, STAT1, IFNA1, IL2

GO Terms for genes affiliated with Parainfluenza Virus Type 3

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17Gene Ontology
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Cellular components related to Parainfluenza Virus Type 3 according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1perinuclear region of cytoplasmGO:0484718.2PRKCZ, EIF2AK2, GAPDH, MX1
2extracellular vesicular exosomeGO:0700627.5NEU1, PRKCZ, ICAM1, NCL, GAPDH, FURIN
3cytosolGO:0058297.2GAPDH, DDX58, RNASEL, PRKCZ, STAT1, IFIH1

Biological processes related to Parainfluenza Virus Type 3 according to GeneCards/GeneDecks:

(show all 17)
idNameGO IDScoreTop Affiliating Genes
1regulation of type III interferon productionGO:03434410.2IFIH1, DDX58
2cytoplasmic pattern recognition receptor signaling pathway in response to virusGO:03952810.2IFIH1, DDX58
3detection of virusGO:00959710.2IFIH1, DDX58
4positive regulation of interferon-alpha productionGO:03272710.1DDX58, IFIH1
5response to exogenous dsRNAGO:04333010.0DDX58, STAT1, IFNB1
6natural killer cell activationGO:0301019.9IL2, IFNB1
7positive regulation of interferon-beta productionGO:0327289.9DDX58, IFIH1
8type I interferon signaling pathwayGO:0603379.8RNASEL, STAT1, IFNB1, MX1
9regulation of type I interferon-mediated signaling pathwayGO:0603389.7IFNB1, STAT1
10negative regulation of viral genome replicationGO:0450719.6RNASEL, IFNB1, EIF2AK2, MX1
11viral processGO:0160329.5IFIH1, STAT1, FURIN, DDX58
12cytokine-mediated signaling pathwayGO:0192219.5RNASEL, ICAM1, STAT1, IFNB1, MX1
13positive regulation of transcription from RNA polymerase II promoterGO:0459449.4IL2, IFNB1, STAT1, RNASEL, DDX58
14response to virusGO:0096159.3MX1, EIF2AK2, IFIH1, IFNB1, DDX58
15defense response to virusGO:0516079.3MX1, EIF2AK2, IFNB1, STAT1, RNASEL
16innate immune responseGO:0450879.2DDX58, IFNB1, IFIH1, EIF2AK2, MX1
17positive regulation of NF-kappaB transcription factor activityGO:0510929.1EIF2AK2, ICAM1, PRKCZ

Molecular functions related to Parainfluenza Virus Type 3 according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1single-stranded RNA bindingGO:00372710.0IFIH1, DDX58
2double-stranded RNA bindingGO:0037259.5EIF2AK2, IFIH1, DDX58
3protein kinase activityGO:0046728.8EIF2AK2, PRKCZ, RNASEL
4identical protein bindingGO:0428028.6STAT1, NCL, GAPDH, DDX58
5protein bindingGO:0055156.5IFIH1, STAT1, ICAM1, PRKCZ, RNASEL, DDX58

Products for genes affiliated with Parainfluenza Virus Type 3

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  • Antibodies
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Sources for Parainfluenza Virus Type 3

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet