MCID: PRL013
MIFTS: 28

Paralytic Poliomyelitis

Categories: Infectious diseases

Aliases & Classifications for Paralytic Poliomyelitis

MalaCards integrated aliases for Paralytic Poliomyelitis:

Name: Paralytic Poliomyelitis 12 14
Poliomyelitis, Paralytic 69

Classifications:



External Ids:

Disease Ontology 12 DOID:0050515
UMLS 69 C1405301

Summaries for Paralytic Poliomyelitis

Disease Ontology : 12 A poliomyelitis that results_in destruction located in motor neurons of central nervous system, has material basis in Human poliovirus 1, has material basis in Human poliovirus 2, or has material basis in Human poliovirus 3, which are transmitted_by ingestion of food or water contaminated with feces, or transmitted_by direct contact with the oral secretions. The infection has symptom loss of reflexes, has symptom muscle spasms, and has symptom acute flaccid paralysis.

MalaCards based summary : Paralytic Poliomyelitis, also known as poliomyelitis, paralytic, is related to poliomyelitis and spinal polio, and has symptoms including loss of reflexes, muscle spasms and acute flaccid paralysis. An important gene associated with Paralytic Poliomyelitis is PVR (Poliovirus Receptor). Affiliated tissues include motor neurons of central nervous system, breast and spinal cord.

Related Diseases for Paralytic Poliomyelitis

Diseases related to Paralytic Poliomyelitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 34)
# Related Disease Score Top Affiliating Genes
1 poliomyelitis 31.9 DPT PVR
2 spinal polio 11.2
3 bulbospinal polio 11.2
4 bulbar polio 11.2
5 aging 10.3
6 pertussis 10.1
7 diphtheria 10.1
8 meningitis 10.1
9 combined immunodeficiency, x-linked 10.0
10 tetanus 10.0
11 aseptic meningitis 10.0
12 agammaglobulinemia 10.0
13 amyotrophic lateral sclerosis 1 9.9
14 blood group, i system 9.9
15 multiple sclerosis 9.9
16 ataxia-telangiectasia 9.9
17 leprosy 3 9.9
18 ataxia and polyneuropathy, adult-onset 9.9
19 mycobacterium tuberculosis 1 9.9
20 west nile virus 9.9
21 acute lymphocytic leukemia 9.9
22 common variable immunodeficiency 9.9
23 leukemia 9.9
24 severe combined immunodeficiency 9.9
25 spinal cord injury 9.9
26 restless legs syndrome 9.9
27 osteomyelitis 9.9
28 mumps 9.9
29 respiratory failure 9.9
30 lateral sclerosis 9.9
31 syringomyelia 9.9
32 myocarditis 9.9
33 hansen's disease 9.9
34 spasticity 9.9

Graphical network of the top 20 diseases related to Paralytic Poliomyelitis:



Diseases related to Paralytic Poliomyelitis

Symptoms & Phenotypes for Paralytic Poliomyelitis

Symptoms:

12
  • loss of reflexes
  • muscle spasms
  • acute flaccid paralysis

Drugs & Therapeutics for Paralytic Poliomyelitis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Study of Mental Fatigue in Polio Survivors Unknown status NCT00487487

Search NIH Clinical Center for Paralytic Poliomyelitis

Genetic Tests for Paralytic Poliomyelitis

Anatomical Context for Paralytic Poliomyelitis

The Foundational Model of Anatomy Ontology organs/tissues related to Paralytic Poliomyelitis:

18
Motor Neurons Of Central Nervous System

MalaCards organs/tissues related to Paralytic Poliomyelitis:

38
Breast, Spinal Cord, Bone

Publications for Paralytic Poliomyelitis

Articles related to Paralytic Poliomyelitis:

(show top 50) (show all 358)
# Title Authors Year
1
Vaccine-associated paralytic poliomyelitis in a patient with acute lymphocytic leukemia. ( 29322435 )
2018
2
Recipient vaccine-associated paralytic poliomyelitis in China, 2010-2015. ( 29395524 )
2018
3
Introduction of Inactivated Poliovirus Vaccine and Impact on Vaccine-Associated Paralytic Poliomyelitis - Beijing, China, 2014-2016. ( 29240729 )
2017
4
Pathogenic Events in a Nonhuman Primate Model of Oral Poliovirus Infection Leading to Paralytic Poliomyelitis. ( 28356537 )
2017
5
Vaccine Associated Paralytic Poliomyelitis Unmasking Common Variable Immunodeficiency. ( 28361789 )
2017
6
A cluster of paralytic poliomyelitis cases due to transmission of slightly diverged Sabin-2 vaccine virus. ( 27099315 )
2016
7
Vaccine associated paralytic poliomyelitis cases from children presenting with acute flaccid paralysis in Uganda. ( 26058454 )
2015
8
Vaccine-associated paralytic poliomyelitis: a case report. ( 24647260 )
2014
9
Effectiveness of oral polio vaccination against paralytic poliomyelitis: a matched case-control study in somalia. ( 25316835 )
2014
10
Vaccine-associated paralytic poliomyelitis in the postelimination era in Latin America and the Caribbean, 1992-2011. ( 24520126 )
2014
11
Examination of motor unit control properties of the vastus lateralis in an individual that had acute paralytic poliomyelitis. ( 25083857 )
2014
12
An unusual case of vaccine-associated paralytic poliomyelitis. ( 25285130 )
2014
13
Circadian variation of fatigue in paralytic poliomyelitis and postpolio syndrome: just fatigue or masked restless legs syndrome? ( 24964120 )
2014
14
Vaccine-associated paralytic poliomyelitis: a review of the epidemiology and estimation of the global burden. ( 25316859 )
2014
15
Outbreaks of paralytic poliomyelitis during 1996-2012: the changing epidemiology of a disease in the final stages of eradication. ( 25316846 )
2014
16
Vaccine-associated paralytic poliomyelitis and BCG-osis in an immigrant child with severe combined immunodeficiency syndrome - Texas, 2013. ( 25144542 )
2014
17
Circadian variation of fatigue in both patients with paralytic poliomyelitis and post-polio syndrome. ( 23857622 )
2013
18
Children with paralytic poliomyelitis: utilization of physiotherapy services in Zamfara State, Nigeria. ( 22871225 )
2013
19
Combined immunodeficiency presenting with vaccine-associated paralytic poliomyelitis: a case report and narrative review of literature. ( 24294834 )
2013
20
Apropos risks associated with the use of live-attenuated vaccine poliovirus strains and the strategies for control and eradication of paralytic poliomyelitis. ( 23249227 )
2012
21
Children with paralytic poliomyelitis: a cross-sectional study of knowledge, attitudes and beliefs of parents in Zamfara state, Nigeria. ( 23083466 )
2012
22
Risks associated with the use of live-attenuated vaccine poliovirus strains and the strategies for control and eradication of paralytic poliomyelitis. ( 22827246 )
2012
23
Vaccine-associated paralytic poliomyelitis in Japan. ( 22325660 )
2012
24
Paralytic poliomyelitis associated with Sabin monovalent and bivalent oral polio vaccines in Hungary. ( 21685412 )
2011
25
Molecular characterization of poliovirus isolates from children who contracted vaccine-associated paralytic poliomyelitis (VAPP) following administration of monovalent type 3 oral poliovirus vaccine in the 1960s in Hungary. ( 19863665 )
2010
26
Vaccine-associated paralytic poliomyelitis in immunodeficient children, Iran, 1995-2008. ( 20587188 )
2010
27
Vaccine-associated paralytic poliomyelitis in a non-immunocompromised infant. ( 20880307 )
2010
28
MR finding in vaccine-associated paralytic poliomyelitis. ( 20567967 )
2010
29
A case of paralytic poliomyelitis associated with poliovirus vaccine strains in Hokkaido, Japan. ( 20495280 )
2010
30
Vaccine-associated paralytic poliomyelitis in an infant with perianal abscesses. ( 20449625 )
2010
31
MRI findings in an infant with vaccine-associated paralytic poliomyelitis. ( 20440488 )
2010
32
Three cases of paralytic poliomyelitis associated with type 3 vaccine poliovirus strains in Bulgaria. ( 19626606 )
2009
33
Ala67Thr mutation in the poliovirus receptor CD155 is a potential risk factor for vaccine and wild-type paralytic poliomyelitis. ( 19319949 )
2009
34
Vaccine - associated paralytic poliomyelitis in a pre-vaccinated infant. ( 18626544 )
2008
35
Vaccine-associated paralytic poliomyelitis in a pre-vaccinated infant. ( 18998027 )
2008
36
Paralytic poliomyelitis during the pre-, peri- and post-suspension periods of a polio immunization campaign. ( 18628551 )
2008
37
Effectiveness of immunization against paralytic poliomyelitis in Nigeria. ( 18923171 )
2008
38
Novel BTK mutation presenting with vaccine-associated paralytic poliomyelitis. ( 18317803 )
2008
39
Poisson-model analysis of the risk of vaccine-associated paralytic poliomyelitis in Japan between 1971 and 2000. ( 18362395 )
2008
40
Vaccine-associated paralytic poliomyelitis: a case report of flaccid monoparesis after oral polio vaccine. ( 17449951 )
2007
41
Characterization of mutations in the VP(1) region of Sabin strain type 1 polioviruses isolated from vaccine-associated paralytic poliomyelitis cases in Iran. ( 17590391 )
2007
42
Vaccine-associated paralytic poliomyelitis in a patient with MHC class II deficiency. ( 17509935 )
2007
43
Clinical presentations of acute paralytic poliomyelitis. ( 16386337 )
2006
44
Vaccine-associated paralytic poliomyelitis caused by contact infection. ( 16617188 )
2006
45
Imported vaccine-associated paralytic poliomyelitis--United States, 2005. ( 16456525 )
2006
46
No evidence for prolonged excretion of polioviruses in persons with residual paralytic poliomyelitis in Ethiopia, Pakistan and Guatemala. ( 16682222 )
2006
47
[Cellular and humoral immunodeficiency in children with vaccine-associated paralytic poliomyelitis]. ( 17297880 )
2006
48
Strength and endurance of knee extensors in subjects after paralytic poliomyelitis. ( 16096231 )
2005
49
Incidence of adaptive equipment use in subjects with a remote history of paralytic poliomyelitis. ( 16186550 )
2005
50
Clinical presentations of acute paralytic poliomyelitis. ( 15970362 )
2005

Variations for Paralytic Poliomyelitis

Expression for Paralytic Poliomyelitis

Search GEO for disease gene expression data for Paralytic Poliomyelitis.

Pathways for Paralytic Poliomyelitis

GO Terms for Paralytic Poliomyelitis

Biological processes related to Paralytic Poliomyelitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell adhesion GO:0007155 8.8 DPT NID1 PVR

Sources for Paralytic Poliomyelitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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