MCID: PRL013
MIFTS: 31

Paralytic Poliomyelitis malady

Summaries for Paralytic Poliomyelitis

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8Disease Ontology, 32MalaCards
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Disease Ontology:8 A poliomyelitis that results in destruction located in motor neurons of central nervous system, has material basis in human poliovirus 1, has material basis in human poliovirus 2, or has material basis in human poliovirus 3, which are transmitted by ingestion of food or water contaminated with feces, or transmitted by direct contact with the oral secretions. the infection has symptom loss of reflexes, has symptom muscle spasms, and has symptom acute flaccid paralysis.

MalaCards: Paralytic Poliomyelitis is related to poliomyelitis and agammaglobulinemia, and has symptoms including loss of reflexes, muscle spasms and acute flaccid paralysis. An important gene associated with Paralytic Poliomyelitis is PVR (poliovirus receptor), and among its related pathways are Cell adhesion molecules (CAMs) and TNF Signaling. The compounds ionomycin and ivig have been mentioned in the context of this disorder. Affiliated tissues include motor neurons of central nervous system, spinal cord and breast.

Aliases & Classifications for Paralytic Poliomyelitis

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8Disease Ontology
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Aliases & Descriptions:

paralytic poliomyelitis 8


External Ids:

Disease Ontology8 DOID:0050515

Related Diseases for Paralytic Poliomyelitis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Paralytic Poliomyelitis:



Diseases related to paralytic poliomyelitis

Clinical Features for Paralytic Poliomyelitis

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8Disease Ontology
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Symptoms:

8
  • loss of reflexes
  • muscle spasms
  • acute flaccid paralysis

Drugs & Therapeutics for Paralytic Poliomyelitis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Paralytic Poliomyelitis

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Anatomical Context for Paralytic Poliomyelitis

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32MalaCards, 14FMA
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MalaCards organs/tissues related to Paralytic Poliomyelitis:

32
Spinal cord, Breast, Bone

FMA organs/tissues related to Paralytic Poliomyelitis:

14
Motor neurons of central nervous system

Animal Models for Paralytic Poliomyelitis or affiliated genes

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Publications for Paralytic Poliomyelitis

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50PubMed
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Articles related to Paralytic Poliomyelitis:

(show top 50)    (show all 347)
idTitleAuthorsYear
1
Paralytic poliomyelitis associated with Sabin monovalent and bivalent oral polio vaccines in Hungary. (21685412)
2011
2
Vaccine - associated paralytic poliomyelitis in a pre-vaccinated infant. (18626544)
2008
3
Periacetabular osteotomy for painful non-paralytic dysplastic hip joints in adults affected by poliomyelitis. (18350733)
2007
4
Paralytic poliomyelitis caused by a vaccine-derived polio virus in an antibody-deficient Argentinean child. (12828159)
2003
5
Vaccine associated paralytic poliomyelitis. (12940380)
2003
6
Endplate dysfunction causing respiratory failure in a patient with prior paralytic poliomyelitis. (12588931)
2003
7
Vaccine-associated paralytic poliomyelitis in Brazil, 1989-1995. (10846924)
2000
8
The logic of causation and the risk of paralytic poliomyelitis for an American child. (10722138)
2000
9
Amyotrophic lateral sclerosis in an adult following acute paralytic poliomyelitis in early childhood. (10090681)
1999
10
Inactivated poliovirus vaccine and vaccine-associated paralytic poliomyelitis. (9002483)
1997
11
Electrophysiological studies in children with paralytic poliomyelitis. (9063660)
1997
12
Prolonged poliovirus excretion in an immunodeficient person with vaccine-associated paralytic poliomyelitis. (9233551)
1997
13
Late functional deterioration following paralytic poliomyelitis. (9093596)
1997
14
Reporting vaccine-associated paralytic poliomyelitis: concordance between the CDC and the National Vaccine Injury Compensation Program. (8629730)
1996
15
Immunization status of hospitalized children with acute paralytic poliomyelitis. (8772852)
1996
16
Vaccine-associated paralytic poliomyelitis in the United States: no evidence of elevated risk after simultaneous intramuscular injections of vaccine. (8584308)
1995
17
Paralytic poliomyelitis: seasoned strategies, disappearing disease. (7910329)
1994
18
Paralytic poliomyelitis in England and Wales, 1985-91. (1322218)
1992
19
Role of breast feeding in paralytic poliomyelitis. (1483099)
1992
20
Survey of village informants--an alternate method to estimate paralytic poliomyelitis prevalence in rural area. (1879905)
1991
21
Prevalence of paralytic poliomyelitis in a rural and urban community of Delhi. (2286434)
1990
22
Observations on the age and spatial distribution of paralytic poliomyelitis in Ibadan, Nigeria. (1699475)
1990
23
Intratypic serodifferentiation of poliovirus type 1 strains isolated during outbreaks of paralytic poliomyelitis. (2840388)
1988
24
Vaccine-associated paralytic poliomyelitis. United States: 1973 through 1984. (3029445)
1987
25
Paralytic poliomyelitis in Italy (1981-85). (3582600)
1987
26
Paralytic poliomyelitis in Guatemala. (3442717)
1987
27
Imported paralytic poliomyelitis--United States, 1986. (3095620)
1986
28
Paralytic poliomyelitis in Finland. (2863531)
1985
29
Paralytic poliomyelitis in children--Part II. Age, sex and seasonal distribution. (3835136)
1985
30
Clinical and serological study of acute paralytic poliomyelitis in immunized and nonimmunized children. (3837775)
1985
31
A clinical profile of paralytic poliomyelitis with special emphasis on physical therapy and rehabilitation. (6642613)
1983
32
A study of incidence of paralytic poliomyelitis in Bhopal: agglomeration from 1972-78. (7262985)
1981
33
Observations on economic impact of paralytic poliomyelitis in children. (544523)
1979
34
Some clinical characteristics of children with paralytic poliomyelitis referred for physiotherapy. (660707)
1978
35
Paralytic poliomyelitis in Ontario: laboratory studies of two recent cases. (4367777)
1973
36
Paralytic poliomyelitis in Norway since the introduction of trivalent oral vaccine: an epidemiological and virological study. (4336552)
1971
37
Incidence of paralytic poliomyelitis and vaccination programme in Turkey. (5968355)
1966
38
Epidemiology of paralytic poliomyelitis. I. Incidence, age and sex distribution. (5932907)
1966
39
Coxsackie A7 virus and paralytic poliomyelitis. (5855230)
1965
40
Illness simulating paralytic poliomyelitis associated with Coxsackie group A type 4 virus infection. (13888769)
1961
41
Studies on paralytic poliomyelitis in Cairo, U.A.R., 1957-1958. (13792243)
1960
42
Paralytic poliomyelitis in Canada, 1950. (13754798)
1960
43
Paralytic poliomyelitis at the University of Alberta Hospital. (13787449)
1960
44
Paralytic poliomyelitis case rates by vaccine status: Aroostook County, Maine, 1959. (14413240)
1960
45
A severe epidemic of paralytic poliomyelitis in western province of Tanganyika, 1956. (13502901)
1958
46
Prevention of urinary calculi after paralytic poliomyelitis. (13587209)
1958
47
Urinary tract infection in paralytic poliomyelitis. (13621987)
1958
48
Paralytic poliomyelitis in a spastic. (13450320)
1957
49
Poliomyelitis and Coxsackie viruses in paralytic poliomyelitis. (14864002)
1951
50
Lesions caused in suckling mice by certain viruses isolated from cases of so called non-paralytic poliomyelitis and of pleurodynia. (15428585)
1950

Genetic Variations for Paralytic Poliomyelitis

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Expression for genes affiliated with Paralytic Poliomyelitis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Paralytic Poliomyelitis

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Pathways for genes affiliated with Paralytic Poliomyelitis

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29KEGG, 55SinoBiological, 52R&D Systems, 37NCBI BioSystems Database, 53Reactome
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Compounds for genes affiliated with Paralytic Poliomyelitis

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44Novoseek
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Compounds related to Paralytic Poliomyelitis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1ionomycin449.1CD40LG, BTK
2ivig448.8CD40LG, BTK

GO Terms for genes affiliated with Paralytic Poliomyelitis

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16Gene Ontology
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Biological processes related to Paralytic Poliomyelitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1regulation of immune responseGO:0507769.4CD40LG, PVR

Products for genes affiliated with Paralytic Poliomyelitis

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Sources for Paralytic Poliomyelitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet