MCID: PRL013
MIFTS: 31

Paralytic Poliomyelitis malady

Categories: Infectious diseases, Neuronal diseases

Aliases & Classifications for Paralytic Poliomyelitis

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Aliases & Descriptions for Paralytic Poliomyelitis:

Name: Paralytic Poliomyelitis 10 12
 
Poliomyelitis, Paralytic 65

Classifications:



External Ids:

Disease Ontology10 DOID:0050515
UMLS65 C1405301

Summaries for Paralytic Poliomyelitis

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Disease Ontology:10 A poliomyelitis that results in destruction located in motor neurons of central nervous system, has material basis in Human poliovirus 1, has material basis in Human poliovirus 2, or has material basis in Human poliovirus 3, which are transmitted by ingestion of food or water contaminated with feces, or transmitted by direct contact with the oral secretions. The infection has symptom loss of reflexes, has symptom muscle spasms, and has symptom acute flaccid paralysis.

MalaCards based summary: Paralytic Poliomyelitis, also known as poliomyelitis, paralytic, is related to poliomyelitis and spinal polio, and has symptoms including loss of reflexes, muscle spasms and acute flaccid paralysis. An important gene associated with Paralytic Poliomyelitis is PVR (Poliovirus Receptor), and among its related pathways are G12-G13 in Cellular Signaling and G-protein signaling Regulation of p38 and JNK signaling mediated by G-proteins. Affiliated tissues include motor neurons of central nervous system, prostate and endothelial.

Related Diseases for Paralytic Poliomyelitis

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Graphical network of the top 20 diseases related to Paralytic Poliomyelitis:



Diseases related to paralytic poliomyelitis

Symptoms for Paralytic Poliomyelitis

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Symptoms:

 10
  • loss of reflexes
  • muscle spasms
  • acute flaccid paralysis

Drugs & Therapeutics for Paralytic Poliomyelitis

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Polio End-game Strategies - Poliovirus Type 2 Challenge StudyCompletedNCT02189811Phase 4
2Study of Mental Fatigue in Polio SurvivorsRecruitingNCT00487487

Search NIH Clinical Center for Paralytic Poliomyelitis

Genetic Tests for Paralytic Poliomyelitis

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Anatomical Context for Paralytic Poliomyelitis

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MalaCards organs/tissues related to Paralytic Poliomyelitis:

33
Prostate, Endothelial, Breast, Monocytes, Lung, T cells, Thyroid

FMA organs/tissues related to Paralytic Poliomyelitis:

16
Motor neurons of central nervous system

Animal Models for Paralytic Poliomyelitis or affiliated genes

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Publications for Paralytic Poliomyelitis

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Articles related to Paralytic Poliomyelitis:

(show top 50)    (show all 352)
idTitleAuthorsYear
1
Primary Breast Angiosarcoma in a Male. (26183811)
2015
2
The absence of mutations in homeobox candidate genes HOXA3, HOXB3, HOXD3 and PITX2 in familial and sporadic thyroid hemiagenesis. (24127533)
2014
3
Nutrition and Pancreatic Enzyme Intake in Patients With Cystic Fibrosis With Distal Intestinal Obstruction Syndrome. (25288253)
2014
4
Paradoxical downregulation of HLA-A expression by IFNI^ associated with schizophrenia and noncoding genes. (23083632)
2013
5
The effect of sildenafil on retinopathy of prematurity in very preterm infants. (22766743)
2013
6
Human cytomegalovirus inhibits apoptosis by proteasome-mediated degradation of Bax at endoplasmic reticulum-mitochondrion contacts. (23487455)
2013
7
Potassium-chloride cotransporter 3 interacts with Vav2 to synchronize the cell volume decrease response with cell protrusion dynamics. (23724134)
2013
8
Endoscopic and Histologic Abnormalities of Gastrointestinal Tract in Patients With Hereditary Hemochromatosis. (24045277)
2013
9
Allergic contact dermatitis: a commentary on the relationship between T lymphocytes and skin sensitising potency. (22120538)
2012
10
Use of intrathecal clonidine in patients with multiple sclerosis or spastic paraparesis. (22057402)
2012
11
Virion-associated complement regulator CD55 is more potent than CD46 in mediating resistance of mumps virus and vesicular stomatitis virus to neutralization. (22761385)
2012
12
Clinical features of a Japanese case with Bothnia dystrophy. (22171637)
2012
13
The frequency of MEFV gene mutations in Behcet's disease and their relation with clinical findings. (21901355)
2012
14
A cost analysis of febrile neutropenia management in Australia: ambulatory v. in-hospital treatment. (22126955)
2011
15
High frequency of low-risk human leukocyte antigen class II genotypes in latent celiac disease. (21075156)
2011
16
Detection of Merkel cell polyomavirus (MCPyV) in Merkel cell carcinoma cell lines: cell morphology and growth phenotype do not reflect presence of the virus. (19739110)
2010
17
Mammary duct ectasia in a man with liver disease, end stage renal failure, and adjacent arteriovenous fistula. (22470751)
2010
18
Imaging of dermatofibrosarcoma protuberans of breast. (20626395)
2010
19
PCR-based methods for CDA K27Q and A70T genotyping: genotypes and alleles distribution in a central Italy population. (19941076)
2010
20
Dynamics of Nampt/visfatin and high molecular weight adiponectin in response to oral glucose load in obese and lean women. (19650786)
2010
21
Higher expression of chemokine receptor CXCR7 is linked to early and metastatic recurrence in pathological stage I nonsmall cell lung cancer. (19309748)
2009
22
Regulation of synaptic structure by ubiquitin C-terminal hydrolase L1. (19535597)
2009
23
A novel ATM-dependent pathway regulates protein phosphatase 1 in response to DNA damage. (18250156)
2008
24
Thermodynamic and dynamic characteristics of monoglyceride monolayers penetrated by beta-casein. (16618167)
2006
25
Research on association between atherosclerotic brain infarction and human leukocyte antigen DR gene]. (16700999)
2006
26
Survivin interacts with Smac/DIABLO in ovarian carcinoma cells but is redundant in Smac-mediated apoptosis. (15541727)
2005
27
Selective inhibition of factor inhibiting hypoxia-inducible factor. (15913349)
2005
28
Correlation between mRNA expression of Th1/Th2 cytokines and their specific transcription factors in human helper T-cell clones. (16174104)
2005
29
NPHS2 mutation analysis shows genetic heterogeneity of steroid-resistant nephrotic syndrome and low post-transplant recurrence. (15253708)
2004
30
Inherited prothrombotic defects in Budd-Chiari syndrome and portal vein thrombosis: a study from North India. (15198356)
2004
31
New studies of the physiopathologic mechanisms of disseminated lupus erythematosus]. (15025269)
2003
32
Serotonin transporter and MAO-B levels in monoamine nuclei of the human brainstem are normal in major depression. (12849931)
2003
33
Otomycosis. (12092275)
2002
34
Efficacy of liposomal amphotericin B in treatment of systemic murine fusariosis. (12069988)
2002
35
High-grade T-cell lymphoma complicating B-cell chronic lymphocytic leukemia: an unusual manifestation of "Richter's syndrome". (11279627)
2001
36
A possible role for thrombopoietin and its receptor c-mpl in the pathobiology of essential thrombocythemia. (9387200)
1997
37
Reversal of drug resistance in multidrug resistant tumor cells by an oligomer complementary to the MDR1 gene]. (15622782)
1997
38
Absence of a mutation of the p21/WAF1 gene in human lung and pancreatic cancers. (8613430)
1996
39
CD23 regulates monocyte activation through a novel interaction with the adhesion molecules CD11b-CD18 and CD11c-CD18. (7621072)
1995
40
Serum concentrations of transferrin receptor in hereditary hemochromatosis. (7600692)
1995
41
Allelic losses on chromosome band 11q13 in aldosterone-producing adrenal tumors. (7534116)
1995
42
Asbestos fiber analysis in seven asbestosis cases. (8117151)
1994
43
Alkaline phosphatase activity in the human promyelocytic leukemia cell line, HL-60, induced by retinoic acid and recombinant human granulocyte colony-stimulating factor. (7689128)
1993
44
Isoforms p69 and p100 of 2',5'-oligoadenylate synthetase induced differentially by interferons in vivo and in vitro. (8454907)
1993
45
Expression of cell surface and cytoskeleton developmentally regulated proteins in adult centronuclear myopathies. (1517767)
1992
46
Immunohistochemistry of Hodgkin and non-Hodgkin lymphomas with emphasis on the diagnostic significance of the BNH9 antibody reactivity with anaplastic large cell (CD30 positive) lymphomas. (1330287)
1992
47
Complete nucleotide sequence of the chromosomal gene for human IL-4 and its expression. (2535858)
1989
48
A fine-structure deletion map of human chromosome 11p: analysis of J1 series hybrids. (2595451)
1989
49
Discoid lupus erythematosus solely involving the eyelids: report of three cases. (3597866)
1987
50
Myocardial changes during the progression of left ventricular pressure-overload by renal hypertension or aortic constriction: myosin, myosin ATPase and collagen. (2951526)
1987

Variations for Paralytic Poliomyelitis

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Expression for genes affiliated with Paralytic Poliomyelitis

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Search GEO for disease gene expression data for Paralytic Poliomyelitis.

Pathways for genes affiliated with Paralytic Poliomyelitis

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Pathways related to Paralytic Poliomyelitis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.5ARHGEF1, BTK
2
Show member pathways
9.5ARHGEF1, BTK
39.5ARHGEF1, BTK

GO Terms for genes affiliated with Paralytic Poliomyelitis

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Sources for Paralytic Poliomyelitis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet