MCID: PRL013
MIFTS: 31

Paralytic Poliomyelitis malady

Summaries for Paralytic Poliomyelitis

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8Disease Ontology, 32MalaCards
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Disease Ontology:8 A poliomyelitis that results in destruction located in motor neurons of central nervous system, has material basis in human poliovirus 1, has material basis in human poliovirus 2, or has material basis in human poliovirus 3, which are transmitted by ingestion of food or water contaminated with feces, or transmitted by direct contact with the oral secretions. the infection has symptom loss of reflexes, has symptom muscle spasms, and has symptom acute flaccid paralysis.

MalaCards: Paralytic Poliomyelitis is related to poliomyelitis and agammaglobulinemia, and has symptoms including muscle spasms, loss of reflexes and acute flaccid paralysis. An important gene associated with Paralytic Poliomyelitis is PVR (poliovirus receptor), and among its related pathways are Cell adhesion molecules (CAMs) and TNF Signaling. The compounds ionomycin and ivig have been mentioned in the context of this disorder. Affiliated tissues include motor neurons of central nervous system, spinal cord and breast.

Aliases & Classifications for Paralytic Poliomyelitis

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8Disease Ontology
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Aliases & Descriptions:

paralytic poliomyelitis 8


External Ids:

Disease Ontology8 DOID:0050515

Related Diseases for Paralytic Poliomyelitis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Paralytic Poliomyelitis:



Diseases related to paralytic poliomyelitis

Clinical Features for Paralytic Poliomyelitis

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8Disease Ontology
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Symptoms:

8
  • muscle spasms
  • loss of reflexes
  • acute flaccid paralysis

Drugs & Therapeutics for Paralytic Poliomyelitis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Paralytic Poliomyelitis

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Anatomical Context for Paralytic Poliomyelitis

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32MalaCards, 14FMA
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MalaCards organs/tissues related to Paralytic Poliomyelitis:

32
Spinal cord, Breast, Bone

FMA organs/tissues related to Paralytic Poliomyelitis:

14
Motor neurons of central nervous system

Animal Models for Paralytic Poliomyelitis or affiliated genes

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Publications for Paralytic Poliomyelitis

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50PubMed
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Articles related to Paralytic Poliomyelitis:

(show top 50)    (show all 347)
idTitleAuthorsYear
1
Risks associated with the use of live-attenuated vaccine poliovirus strains and the strategies for control and eradication of paralytic poliomyelitis. (22827246)
2012
2
MR finding in vaccine-associated paralytic poliomyelitis. (20567967)
2010
3
Imported vaccine-associated paralytic poliomyelitis--United States, 2005. (16456525)
2006
4
Paralytic poliomyelitis associated with live oral poliomyelitis vaccine in child with HIV infection in Zimbabwe: case report. (10092261)
1999
5
Vaccine-associated paralytic poliomyelitis. (8989358)
1997
6
Epidemiological considerations on age distribution of paralytic poliomyelitis. (8816037)
1996
7
Total hip replacement in a limb severely affected by paralytic poliomyelitis. (7634209)
1995
8
Electrophysiological studies in children with paralytic poliomyelitis. (7781576)
1995
9
Acute paralytic poliomyelitis in Delhi (1975-1992). (7927614)
1994
10
Paralytic poliomyelitis--an imported case. (7506101)
1993
11
Ataxia-telangiectasia in a child with vaccine-associated paralytic poliomyelitis. (1517916)
1992
12
Update: eradication of paralytic poliomyelitis in the Americas. (1381040)
1992
13
AAEM case report #23: acute paralytic poliomyelitis. (1766446)
1991
14
Paralytic poliomyelitis outbreak in Gizan, Saudi Arabia. (1960781)
1991
15
Perspectives on rapid elimination and ultimate global eradication of paralytic poliomyelitis caused by polioviruses. (1646116)
1991
16
A new epidemiologic and laboratory classification system for paralytic poliomyelitis cases. (2929811)
1989
17
Paralytic poliomyelitis--Senegal, 1986-1987: update on the N-IPV efficacy study. (3128726)
1988
18
Prevalence of paralytic poliomyelitis in rural and urban populations in Ethiopia: report of a house-to-house survey. (3275143)
1988
19
Paralytic poliomyelitis in vaccinated children. (3610288)
1987
20
Paralytic poliomyelitis in Benin City in Nigeria. (3786652)
1986
21
Outbreak of paralytic poliomyelitis in Finland: widespread circulation of antigenically altered poliovirus type 3 in a vaccinated population. (2872526)
1986
22
Paralytic poliomyelitis. Rehabilitation point of view. (4077259)
1985
23
Control of paralytic poliomyelitis in the United States. (6740085)
1984
24
Outbreak of paralytic poliomyelitis, Taiwan. (6150332)
1984
25
Prospects for worldwide control of paralytic poliomyelitis: a discussion. (6740109)
1984
26
Can paralytic poliomyelitis be eliminated? (6740105)
1984
27
Residual paralytic poliomyelitis in a tropical region of Brazil, 1969-1977: prevalence surveys in different age groups as indicators of changing incidence. (6829549)
1983
28
Paralytic poliomyelitis: Old dogmas and new perspectives. (6269169)
1981
29
Late sequelae of paralytic poliomyelitis: a clinical and electromyographic study. (422959)
1979
30
HLA-A, -B, and -D antigens in paralytic poliomyelitis. (88778)
1979
31
An association of HL-A3 and HL-A7 with paralytic poliomyelitis. (4837313)
1974
32
Paralytic poliomyelitis following inoculation with combined diphtheria-tetanus-pertussis prophylactic. A review of sixteen cases with special reference to immunisation schedules in infancy. (4720095)
1973
33
Paralytic poliomyelitis: contacts of vaccinated children. (6054763)
1967
34
Vaccine-acquired paralytic poliomyelitis in an unvaccinated mother. (5953205)
1966
35
Clinical paralytic poliomyelitis due to enteroviruses other than poliovirus. (13983659)
1963
36
Evaluation of transaminase activity in the cerebrospinal fluid in paralytic poliomyelitis. Preliminary report. (13680912)
1961
37
Mumps virus infection simulating paralytic poliomyelitis. A report of 11 cases. (14415711)
1960
38
Creatinine and creatine clearance in the acute stage of paralytic poliomyelitis. (14408218)
1960
39
Paralytic Poliomyelitis in Canada. (20325979)
1959
40
Occurrence of myocarditis in paralytic poliomyelitis. (13826196)
1959
41
Prognosis of limb inequality following paralytic poliomyelitis. (13612205)
1958
42
C reactive protein in serous meningitis and paralytic poliomyelitis. (13470510)
1957
43
Clinical aspects of non-paralytic poliomyelitis and a clinical comparison of poliomyelitis epidemics due to type I and type II virus. (14382886)
1955
44
The epidemiology of paralytic poliomyelitis in Hawaii. (13162361)
1954
45
Prevention of paralytic poliomyelitis in tonsillectomized cynomolgus monkeys by human gamma globulin. (13023105)
1953
46
Five case of paralytic poliomyelitis in a family. (13012412)
1952
47
Second attacks of paralytic poliomyelitis in human beings in relation to immunity, virus types and virulence, with a report of two cases, and four other individuals in Baltimore, 1944, infected with virus of the Leon type. (14877798)
1951
48
Non-Paralytic Poliomyelitis. (18731669)
1950
49
A virus isolated from patients diagnosed as non-paralytic poliomyelitis or aseptic meningitis. (18136475)
1949
50
NATURE OF NON-PARALYTIC AND TRANSITORY PARALYTIC POLIOMYELITIS IN RHESUS MONKEYS INOCULATED WITH HUMAN VIRUS. (19871110)
1941

Genetic Variations for Paralytic Poliomyelitis

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Expression for genes affiliated with Paralytic Poliomyelitis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Paralytic Poliomyelitis

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Pathways for genes affiliated with Paralytic Poliomyelitis

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29KEGG, 55SinoBiological, 52R&D Systems, 37NCBI BioSystems Database, 53Reactome
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Compounds for genes affiliated with Paralytic Poliomyelitis

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44Novoseek
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Compounds related to Paralytic Poliomyelitis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1ionomycin449.1CD40LG, BTK
2ivig448.8CD40LG, BTK

GO Terms for genes affiliated with Paralytic Poliomyelitis

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16Gene Ontology
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Biological processes related to Paralytic Poliomyelitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1regulation of immune responseGO:0507769.4CD40LG, PVR

Products for genes affiliated with Paralytic Poliomyelitis

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Sources for Paralytic Poliomyelitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet