MCID: PRL013
MIFTS: 31

Paralytic Poliomyelitis malady

Categories: Infectious diseases, Neuronal diseases

Aliases & Classifications for Paralytic Poliomyelitis

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Aliases & Descriptions for Paralytic Poliomyelitis:

Name: Paralytic Poliomyelitis 10 12
 
Poliomyelitis, Paralytic 65

Classifications:



External Ids:

Disease Ontology10 DOID:0050515
UMLS65 C1405301

Summaries for Paralytic Poliomyelitis

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Disease Ontology:10 A poliomyelitis that results in destruction located in motor neurons of central nervous system, has material basis in Human poliovirus 1, has material basis in Human poliovirus 2, or has material basis in Human poliovirus 3, which are transmitted by ingestion of food or water contaminated with feces, or transmitted by direct contact with the oral secretions. The infection has symptom loss of reflexes, has symptom muscle spasms, and has symptom acute flaccid paralysis.

MalaCards based summary: Paralytic Poliomyelitis, also known as poliomyelitis, paralytic, is related to poliomyelitis and spinal polio, and has symptoms including loss of reflexes, muscle spasms and acute flaccid paralysis. An important gene associated with Paralytic Poliomyelitis is PVR (Poliovirus Receptor), and among its related pathways are G12-G13 in Cellular Signaling and G-protein signaling Regulation of p38 and JNK signaling mediated by G-proteins. Affiliated tissues include motor neurons of central nervous system, breast and heart.

Related Diseases for Paralytic Poliomyelitis

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Graphical network of the top 20 diseases related to Paralytic Poliomyelitis:



Diseases related to paralytic poliomyelitis

Symptoms for Paralytic Poliomyelitis

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Symptoms:

 10
  • loss of reflexes
  • muscle spasms
  • acute flaccid paralysis

Drugs & Therapeutics for Paralytic Poliomyelitis

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Polio End-game Strategies - Poliovirus Type 2 Challenge StudyCompletedNCT02189811Phase 4
2Study of Mental Fatigue in Polio SurvivorsRecruitingNCT00487487

Search NIH Clinical Center for Paralytic Poliomyelitis

Genetic Tests for Paralytic Poliomyelitis

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Anatomical Context for Paralytic Poliomyelitis

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MalaCards organs/tissues related to Paralytic Poliomyelitis:

33
Breast, Heart, Thyroid, Prostate, Endothelial, T cells, Myeloid

FMA organs/tissues related to Paralytic Poliomyelitis:

16
Motor neurons of central nervous system

Animal Models for Paralytic Poliomyelitis or affiliated genes

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Publications for Paralytic Poliomyelitis

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Articles related to Paralytic Poliomyelitis:

(show top 50)    (show all 353)
idTitleAuthorsYear
1
A cluster of paralytic poliomyelitis cases due to transmission of slightly diverged Sabin-2 vaccine virus. (27099315)
2016
2
Vaccine-associated paralytic poliomyelitis: a case report. (24647260)
2014
3
An unusual case of vaccine-associated paralytic poliomyelitis. (25285130)
2014
4
Vaccine-associated paralytic poliomyelitis in immunodeficient children, Iran, 1995-2008. (20587188)
2010
5
MR finding in vaccine-associated paralytic poliomyelitis. (20567967)
2010
6
A case of paralytic poliomyelitis associated with poliovirus vaccine strains in Hokkaido, Japan. (20495280)
2010
7
Ala67Thr mutation in the poliovirus receptor CD155 is a potential risk factor for vaccine and wild-type paralytic poliomyelitis. (19319949)
2009
8
Clinical presentations of acute paralytic poliomyelitis. (16386337)
2006
9
Paralytic poliomyelitis caused by a vaccine-derived polio virus in an antibody-deficient Argentinean child. (12828159)
2003
10
The neuropathology observed in wild-type mice inoculated with human poliovirus mirrors human paralytic poliomyelitis. (12220986)
2002
11
A case of vaccine-associated paralytic poliomyelitis. (11291633)
2001
12
Amyotrophic lateral sclerosis in an adult following acute paralytic poliomyelitis in early childhood. (10090681)
1999
13
Vaccine-associated paralytic poliomyelitis. (8989358)
1997
14
Epidemiological considerations on age distribution of paralytic poliomyelitis. (8816037)
1996
15
Immunization status in hospitalized children with acute paralytic poliomyelitis. (8935263)
1995
16
Completeness of reporting for paralytic poliomyelitis, United States, 1980 through 1991. Implications for estimating the risk of vaccine-associated disease. (8180638)
1994
17
Paralytic poliomyelitis in Romania, 1984-1992. Evidence for a high risk of vaccine-associated disease and reintroduction of wild-virus infection. (7998593)
1994
18
Acute paralytic poliomyelitis in Delhi (1975-1992). (7927614)
1994
19
Ataxia-telangiectasia in a child with vaccine-associated paralytic poliomyelitis. (1517916)
1992
20
Update: eradication of paralytic poliomyelitis in the Americas. (1381040)
1992
21
Paralytic poliomyelitis. (1538863)
1992
22
AAEM case report #23: acute paralytic poliomyelitis. (1766446)
1991
23
Prevalence of paralytic poliomyelitis in a rural and urban community of Delhi. (2286434)
1990
24
Impact of annual immunisation programme with oral polio vaccine on the prevalence of paralytic poliomyelitis. (2807469)
1989
25
Paralytic poliomyelitis in vaccinated children. (3683754)
1987
26
Imported paralytic poliomyelitis--United States, 1986. (3095620)
1986
27
Paralytic poliomyelitis in children in Ethiopia: a review of 2604 cases. (3698975)
1986
28
Outbreak of paralytic poliomyelitis. (2857255)
1985
29
Paralytic poliomyelitis in Finland. (2863531)
1985
30
Paralytic poliomyelitis in children: some facts and figures from a hospital at Calcutta--1. (3835135)
1985
31
Antigenic analysis of polioviruses isolated from a child with agammaglobulinemia and paralytic poliomyelitis after Sabin vaccine administration. (6273701)
1981
32
A study of incidence of paralytic poliomyelitis in Bhopal: agglomeration from 1972-78. (7262985)
1981
33
Comparison of methods for estimating the frequency of paralytic poliomyelitis in developing countries. (312162)
1979
34
Observations on economic impact of paralytic poliomyelitis in children. (544523)
1979
35
Paralytic poliomyelitis in children. (924651)
1977
36
Acute paralytic poliomyelitis at Kenyatta National Hospital 1969-1971. (4845811)
1974
37
Guest editorial: outbreak of paralytic poliomyelitis. (4687474)
1973
38
Role of breast feeding in paralytic poliomyelitis with special reference to immunisation. (5028650)
1972
39
Studies on paralytic poliomyelitis in Cairo, U.A.R., 1957-1958. (13792243)
1960
40
Preconceptions about vaccination against paralytic poliomyelitis. (13637560)
1959
41
Recurrent paralytic poliomyelitis; report of a case, documented with virus isolations. (13657362)
1959
42
Paralytic Poliomyelitis in Canada, Week ending October 4, 1958. (20325819)
1958
43
Prognosis of limb inequality following paralytic poliomyelitis. (13612205)
1958
44
A severe epidemic of paralytic poliomyelitis in western province of Tanganyika, 1956. (13502901)
1958
45
Study of cases of paralytic poliomyelitis in triply-vaccinated persons. (13569855)
1958
46
C reactive protein in serous meningitis and paralytic poliomyelitis. (13470510)
1957
47
Glossopharyngeal breathing as an aid to recovery from paralytic poliomyelitis. (13313534)
1956
48
Paralytic poliomyelitis. (14371167)
1955
49
Observations on the use of gamma globulin as a control measure in paralytic poliomyelitis in siblings; report of two cases. (13213643)
1954
50
POSSIBLE relationship between paralytic poliomyelitis and subcutaneous injection of immunizing agents and other medicinal substances. (14911309)
1952

Variations for Paralytic Poliomyelitis

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Expression for genes affiliated with Paralytic Poliomyelitis

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Search GEO for disease gene expression data for Paralytic Poliomyelitis.

Pathways for genes affiliated with Paralytic Poliomyelitis

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Pathways related to Paralytic Poliomyelitis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.5ARHGEF1, BTK
2
Show member pathways
9.5ARHGEF1, BTK
39.5ARHGEF1, BTK

GO Terms for genes affiliated with Paralytic Poliomyelitis

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Sources for Paralytic Poliomyelitis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet