MCID: PRL014
MIFTS: 25

Paralytic Squint

Categories: Eye diseases, Neuronal diseases

Aliases & Classifications for Paralytic Squint

MalaCards integrated aliases for Paralytic Squint:

Name: Paralytic Squint 12 14
Paralytic Strabismus 12 69
Incomitant Dissociation 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10863
ICD10 33 H49 H49.9
ICD9CM 35 378.5 378.50
UMLS 69 C0152221

Summaries for Paralytic Squint

MalaCards based summary : Paralytic Squint, also known as paralytic strabismus, is related to abducens nerve disease and autosomal recessive spastic paraplegia type 68. An important gene associated with Paralytic Squint is TUBB3 (Tubulin Beta 3 Class III), and among its related pathways/superpathways is Glypican 1 network. Affiliated tissues include eye.

Wikipedia : 72 Strabismus, also called crossed eyes, is a condition in which the eyes do not properly align with each... more...

Related Diseases for Paralytic Squint

Diseases related to Paralytic Squint via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 59)
id Related Disease Score Top Affiliating Genes
1 abducens nerve disease 22.1 CADM1 CHN1 EPHA4 FUT2 GABBR1 HCK
2 autosomal recessive spastic paraplegia type 68 10.8 TUBB2B TUBB3
3 coloboma of macula and skeletal anomalies 10.7 CHN1 TUBB3
4 autism susceptibility 17 10.7 KIF21A PHOX2A
5 disseminated intravascular coagulation 10.6 TUBB2B TUBB3
6 ulceration of vulva 10.6 CHN1 KIF21A TUBB3
7 porencephaly 10.5 KIF21A PHOX2A TUBB3
8 peters-plus syndrome 10.5 PHOX2A TUBB3
9 mental retardation with spastic paraplegia 10.5 KIF21A PHOX2A TUBB3
10 villonodular synovitis 10.5 CHN1 KANTR
11 monofixation syndrome 10.5 CHN1 TUBB3
12 mental retardation, autosomal recessive 59 10.4 CHN1 KIF21A TUBB2B TUBB3
13 endometriosis of ovary 10.4 CHN1 KIF21A PHOX2A TUBB3
14 fuchs' endothelial dystrophy 10.4 CHN1 KANTR
15 enterocele 10.4 CHN1 KIF21A PHOX2A TUBB3
16 adenosquamous bile duct carcinoma 10.4 CHN1 KANTR
17 paget's disease of bone 10.4 CHN1 KIF21A PHOX2A TUBB3
18 bacterial meningitis 10.4 KANTR TUBB3
19 focal hand dystonia 10.3 FUT2 KANTR
20 nutritional optic neuropathy 10.3 HCK KANTR
21 fungal meningitis 10.3 HCK KANTR
22 malignant melanocytic neoplasm of the peripheral nerve sheath 10.2 KANTR SAMHD1
23 color agnosia 10.2 KANTR PRNP
24 strabismus 10.2
25 benign paroxysmal positional nystagmus 10.2 CADM1 KANTR TUBB3
26 localized chondrosarcoma 10.2 FUT2 KANTR
27 kearns-sayre syndrome 10.2
28 microcephaly-micromelia syndrome 10.2 CHN1 KIF21A PHOX2A TUBB2B TUBB3
29 interstitial emphysema 10.1 KANTR SH3BP5
30 tukel syndrome 10.1
31 chronic progressive external ophthalmoplegia 10.1
32 tolosa-hunt syndrome 10.1
33 pancreatic acinar cell adenocarcinoma 10.1 CHN1 KANTR KIF21A TUBB3
34 total circumpapillary dystrophy of choroid 10.1 CHN1 KANTR SAMHD1
35 cardiovascular cancer 10.0 CADM1 KANTR PHOX2A TUBB3
36 gaze palsy, familial horizontal, with progressive scoliosis, 1 9.9
37 autosomal dominant progressive external ophthalmoplegia 9.9
38 progressive external ophthalmoplegia, autosomal recessive 1 9.9
39 maternally-inherited progressive external ophthalmoplegia 9.9
40 congenital trochlear nerve palsy 9.9
41 fourth cranial nerve palsy, familial congenital 9.9
42 total third-nerve palsy 9.9
43 fourth cranial nerve palsy 9.9
44 oculomotor nerve paralysis 9.9
45 trochlear nerve disease 9.9
46 prostate carcinoma in situ 9.9 KANTR PRNP TUBB3
47 macrocystic neurilemmoma 9.9 KANTR SAMHD1
48 pleomorphic carcinoma 9.9 CHN1 KANTR KIF21A PHOX2A TUBB3
49 uterine inversion 9.9 HCK KANTR
50 long bones of lower limb cancer 9.8 CADM1 GABBR1 MTRNR2L5

Graphical network of the top 20 diseases related to Paralytic Squint:



Diseases related to Paralytic Squint

Symptoms & Phenotypes for Paralytic Squint

Drugs & Therapeutics for Paralytic Squint

Search Clinical Trials , NIH Clinical Center for Paralytic Squint

Genetic Tests for Paralytic Squint

Anatomical Context for Paralytic Squint

MalaCards organs/tissues related to Paralytic Squint:

39
Eye

Publications for Paralytic Squint

Articles related to Paralytic Squint:

id Title Authors Year
1
Paralytic squint due to abducens nerve palsy: a rare consequence of dengue fever. ( 22799448 )
2012
2
Paralytic squint treated with acupuncture. ( 6570146 )
1984
3
The use of prisms in paralytic squint. ( 900621 )
1977
4
A surgery on twenty six thousand and three hundred seventy eight patients with convergent squint (26378), thirteen thousand, one hundred and eighty one patients with divergent squint (13181), one thousand and twenty nine patients of vertical squint (1029), ten thousand and one hundred thirty nine patients of heterophoria (10139) and two thousand sixty one patients of paralytic squint (2061) seen during the past ten years at Giza Ophthalmic Hospital Squint Clinic from the year 1960 to the year 1970. ( 4666806 )
1972
5
Diagnosis of paralytic squint. ( 5154750 )
1971
6
NON-PARALYTIC squint. ( 13450382 )
1957
7
Clinical orthoptic procedure: paralytic squint. ( 20295365 )
1947
8
Paralytic squint. ( 20295367 )
1947
9
SOME CASES OF PARALYTIC SQUINT. ( 18169478 )
1937

Variations for Paralytic Squint

Expression for Paralytic Squint

Search GEO for disease gene expression data for Paralytic Squint.

Pathways for Paralytic Squint

Pathways related to Paralytic Squint according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.04 HCK PRNP

GO Terms for Paralytic Squint

Cellular components related to Paralytic Squint according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 dendrite GO:0030425 8.92 EPHA4 GABBR1 PRNP TUBB3

Biological processes related to Paralytic Squint according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 regulation of axonogenesis GO:0050770 9.16 CHN1 EPHA4
2 motor neuron axon guidance GO:0008045 8.96 CHN1 EPHA4
3 negative regulation of long-term synaptic potentiation GO:1900272 8.32 PRNP

Sources for Paralytic Squint

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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