MCID: PRL014
MIFTS: 25

Paralytic Squint malady

Categories: Eye diseases, Neuronal diseases

Aliases & Classifications for Paralytic Squint

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Aliases & Descriptions for Paralytic Squint:

Name: Paralytic Squint 11 13
Paralytic Strabismus 11 68
 
Incomitant Dissociation 11

Classifications:



External Ids:

Disease Ontology11 DOID:10863
ICD1030 H49, H49.9
ICD9CM32 378.5, 378.50

Summaries for Paralytic Squint

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Wikipedia:71 Strabismus, also called crossed eyes, is a condition in which the eyes do not properly align with each... more...

MalaCards based summary: Paralytic Squint, also known as paralytic strabismus, is related to total third-nerve palsy and neurodegeneration due to cerebral folate transport deficiency. An important gene associated with Paralytic Squint is CHN1 (Chimerin 1), and among its related pathways is Glypican 1 network. Affiliated tissues include eye.

Related Diseases for Paralytic Squint

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Diseases related to Paralytic Squint via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 51)
idRelated DiseaseScoreTop Affiliating Genes
1total third-nerve palsy26.8CADM1, CHN1, EPHA4, FUT2, GABBR1, HCK
2neurodegeneration due to cerebral folate transport deficiency10.3KIF21A, PHOX2A
3endometriosis of ovary10.2CHN1, KIF21A, PHOX2A
4strabismus10.2
5infected hydrocele10.2CHN1, KANTR
6kearns-sayre syndrome10.2
7acral lentiginous melanoma10.1KANTR, SAMHD1
8malignant neoplasm of short bones of lower limb10.1CADM1, GABBR1, MTRNR2L5
9fungal meningitis10.1HCK, KANTR
10nutritional optic neuropathy10.1HCK, KANTR
11tukel syndrome10.1
12abducens nerve disease10.1
13chronic progressive external ophthalmoplegia10.1
14tolosa-hunt syndrome10.1
15febrile seizures, familial, 110.1CHN1, KIF21A, TUBB3
16interstitial keratitis10.1CHN1, KANTR, SAMHD1
17ampulla of vater adenosquamous carcinoma10.1CHN1, KANTR
18amyotrophic neuralgia10.1CHN1, PHOX2A, TUBB3
19tubulointerstitial nephritis with uveitis10.1CHN1, TUBB3
20ulceration of vulva10.1CHN1, KIF21A, TUBB3
21nerve fibre bundle defect10.0CHN1, KANTR, KIF21A, PHOX2A
22iliac vein thrombophlebitis10.0CHN1, HCK, PRL, PRNP
23mental retardation with spastic paraplegia10.0KIF21A, PHOX2A, TUBB3
24oculogyric crisis10.0FUT2, KANTR
25chronic lacrimal gland enlargement10.0CHN1, KIF21A, PHOX2A, TUBB3
26urinary bladder villous adenoma10.0CHN1, KIF21A, PHOX2A, TUBB3
27pontocerebellar hypoplasia10.0CHN1, KIF21A, PHOX2A, TUBB3
28benign paroxysmal positional nystagmus10.0CADM1, KANTR, MTRNR2L5
29acute serous otitis media10.0CHN1, KANTR
30gaze palsy, horizontal, with progressive scoliosis9.9
31progressive external ophthalmoplegia, autosomal recessive 19.9
32fourth cranial nerve palsy, familial congenital9.9
33fourth cranial nerve palsy9.9
34oculomotor nerve paralysis9.9
35trochlear nerve disease9.9
36autosomal dominant progressive external ophthalmoplegia9.9
37maternally-inherited progressive external ophthalmoplegia9.9
38congenital trochlear nerve palsy9.9
39cardiovascular cancer9.9CADM1, KANTR, MTRNR2L5, PHOX2A
40astroblastoma9.9KANTR, MTRNR2L5, PRL
41uterine ligament serous adenocarcinoma9.9CHN1, KANTR, TUBB3
42autosomal recessive spastic paraplegia type 709.9TUBB2B, TUBB3
43ulcerative blepharitis9.9KANTR, TUBB3
44alopecia areata9.9CHN1, KIF21A, PHOX2A, SAMHD1, TUBB3
45y chromosome infertility9.8TUBB2B, TUBB3
46lingual-facial-buccal dyskinesia9.8CHN1, KANTR, KIF21A, SAMHD1, TUBB3
47keratopathy9.8
48thrombosis9.8
49lyme disease9.8
50blepharospasm9.8

Graphical network of the top 20 diseases related to Paralytic Squint:



Diseases related to paralytic squint

Symptoms & Phenotypes for Paralytic Squint

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Drugs & Therapeutics for Paralytic Squint

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Paralytic Squint

Genetic Tests for Paralytic Squint

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Anatomical Context for Paralytic Squint

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MalaCards organs/tissues related to Paralytic Squint:

36
Eye

Publications for Paralytic Squint

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Articles related to Paralytic Squint:

idTitleAuthorsYear
1
Paralytic squint due to abducens nerve palsy: a rare consequence of dengue fever. (22799448)
2012
2
Paralytic squint treated with acupuncture. (6570146)
1984
3
The use of prisms in paralytic squint. (900621)
1977
4
A surgery on twenty six thousand and three hundred seventy eight patients with convergent squint (26378), thirteen thousand, one hundred and eighty one patients with divergent squint (13181), one thousand and twenty nine patients of vertical squint (1029), ten thousand and one hundred thirty nine patients of heterophoria (10139) and two thousand sixty one patients of paralytic squint (2061) seen during the past ten years at Giza Ophthalmic Hospital Squint Clinic from the year 1960 to the year 1970. (4666806)
1972
5
Diagnosis of paralytic squint. (5154750)
1971
6
NON-PARALYTIC squint. (13450382)
1957
7
Paralytic squint. (20295367)
1947
8
Clinical orthoptic procedure: paralytic squint. (20295365)
1947
9
SOME CASES OF PARALYTIC SQUINT. (18169478)
1937

Variations for Paralytic Squint

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Expression for genes affiliated with Paralytic Squint

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Search GEO for disease gene expression data for Paralytic Squint.

Pathways for genes affiliated with Paralytic Squint

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Pathways related to Paralytic Squint according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.9HCK, PRNP

GO Terms for genes affiliated with Paralytic Squint

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Cellular components related to Paralytic Squint according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1dendriteGO:00304259.0EPHA4, GABBR1, PRNP, TUBB3

Biological processes related to Paralytic Squint according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1motor neuron axon guidanceGO:000804510.1CHN1, EPHA4
2regulation of axonogenesisGO:00507709.8CHN1, EPHA4

Molecular functions related to Paralytic Squint according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1ephrin receptor bindingGO:00468759.8CHN1, EPHA4

Sources for Paralytic Squint

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet