MCID: PRL014
MIFTS: 25

Paralytic Squint malady

Categories: Eye diseases, Neuronal diseases

Aliases & Classifications for Paralytic Squint

Aliases & Descriptions for Paralytic Squint:

Name: Paralytic Squint 12 14
Paralytic Strabismus 12 69
Incomitant Dissociation 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10863
ICD10 33 H49 H49.9
ICD9CM 35 378.5 378.50
UMLS 69 C0152221

Summaries for Paralytic Squint

MalaCards based summary : Paralytic Squint, also known as paralytic strabismus, is related to total third-nerve palsy and neurodegeneration due to cerebral folate transport deficiency. An important gene associated with Paralytic Squint is CHN1 (Chimerin 1), and among its related pathways/superpathways is Glypican 1 network. Affiliated tissues include eye.

Wikipedia : 71 Strabismus, also called crossed eyes, is a condition in which the eyes do not properly align with each... more...

Related Diseases for Paralytic Squint

Diseases related to Paralytic Squint via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 51)
id Related Disease Score Top Affiliating Genes
1 total third-nerve palsy 26.8 CADM1 CHN1 EPHA4 FUT2 GABBR1 HCK
2 neurodegeneration due to cerebral folate transport deficiency 10.3 KIF21A PHOX2A
3 endometriosis of ovary 10.2 CHN1 KIF21A PHOX2A
4 strabismus 10.2
5 infected hydrocele 10.2 CHN1 KANTR
6 kearns-sayre syndrome 10.2
7 acral lentiginous melanoma 10.1 KANTR SAMHD1
8 malignant neoplasm of short bones of lower limb 10.1 CADM1 GABBR1 MTRNR2L5
9 fungal meningitis 10.1 HCK KANTR
10 nutritional optic neuropathy 10.1 HCK KANTR
11 tukel syndrome 10.1
12 abducens nerve disease 10.1
13 chronic progressive external ophthalmoplegia 10.1
14 tolosa-hunt syndrome 10.1
15 febrile seizures, familial, 1 10.1 CHN1 KIF21A TUBB3
16 interstitial keratitis 10.1 CHN1 KANTR SAMHD1
17 ampulla of vater adenosquamous carcinoma 10.1 CHN1 KANTR
18 amyotrophic neuralgia 10.1 CHN1 PHOX2A TUBB3
19 tubulointerstitial nephritis with uveitis 10.1 CHN1 TUBB3
20 ulceration of vulva 10.1 CHN1 KIF21A TUBB3
21 nerve fibre bundle defect 10.0 CHN1 KANTR KIF21A PHOX2A
22 iliac vein thrombophlebitis 10.0 CHN1 HCK PRL PRNP
23 mental retardation with spastic paraplegia 10.0 KIF21A PHOX2A TUBB3
24 oculogyric crisis 10.0 FUT2 KANTR
25 chronic lacrimal gland enlargement 10.0 CHN1 KIF21A PHOX2A TUBB3
26 urinary bladder villous adenoma 10.0 CHN1 KIF21A PHOX2A TUBB3
27 pontocerebellar hypoplasia 10.0 CHN1 KIF21A PHOX2A TUBB3
28 benign paroxysmal positional nystagmus 10.0 CADM1 KANTR MTRNR2L5
29 acute serous otitis media 10.0 CHN1 KANTR
30 gaze palsy, horizontal, with progressive scoliosis 9.9
31 autosomal dominant progressive external ophthalmoplegia 9.9
32 progressive external ophthalmoplegia, autosomal recessive 1 9.9
33 maternally-inherited progressive external ophthalmoplegia 9.9
34 congenital trochlear nerve palsy 9.9
35 fourth cranial nerve palsy, familial congenital 9.9
36 fourth cranial nerve palsy 9.9
37 oculomotor nerve paralysis 9.9
38 trochlear nerve disease 9.9
39 cardiovascular cancer 9.9 CADM1 KANTR MTRNR2L5 PHOX2A
40 astroblastoma 9.9 KANTR MTRNR2L5 PRL
41 uterine ligament serous adenocarcinoma 9.9 CHN1 KANTR TUBB3
42 autosomal recessive spastic paraplegia type 70 9.9 TUBB2B TUBB3
43 ulcerative blepharitis 9.9 KANTR TUBB3
44 alopecia areata 9.9 CHN1 KIF21A PHOX2A SAMHD1 TUBB3
45 y chromosome infertility 9.8 TUBB2B TUBB3
46 lingual-facial-buccal dyskinesia 9.8 CHN1 KANTR KIF21A SAMHD1 TUBB3
47 blepharospasm 9.8
48 keratopathy 9.8
49 thrombosis 9.8
50 lyme disease 9.8

Graphical network of the top 20 diseases related to Paralytic Squint:



Diseases related to Paralytic Squint

Symptoms & Phenotypes for Paralytic Squint

Drugs & Therapeutics for Paralytic Squint

Search Clinical Trials , NIH Clinical Center for Paralytic Squint

Genetic Tests for Paralytic Squint

Anatomical Context for Paralytic Squint

MalaCards organs/tissues related to Paralytic Squint:

39
Eye

Publications for Paralytic Squint

Articles related to Paralytic Squint:

id Title Authors Year
1
Paralytic squint due to abducens nerve palsy: a rare consequence of dengue fever. ( 22799448 )
2012
2
Paralytic squint treated with acupuncture. ( 6570146 )
1984
3
The use of prisms in paralytic squint. ( 900621 )
1977
4
A surgery on twenty six thousand and three hundred seventy eight patients with convergent squint (26378), thirteen thousand, one hundred and eighty one patients with divergent squint (13181), one thousand and twenty nine patients of vertical squint (1029), ten thousand and one hundred thirty nine patients of heterophoria (10139) and two thousand sixty one patients of paralytic squint (2061) seen during the past ten years at Giza Ophthalmic Hospital Squint Clinic from the year 1960 to the year 1970. ( 4666806 )
1972
5
Diagnosis of paralytic squint. ( 5154750 )
1971
6
NON-PARALYTIC squint. ( 13450382 )
1957
7
Paralytic squint. ( 20295367 )
1947
8
Clinical orthoptic procedure: paralytic squint. ( 20295365 )
1947
9
SOME CASES OF PARALYTIC SQUINT. ( 18169478 )
1937

Variations for Paralytic Squint

Expression for Paralytic Squint

Search GEO for disease gene expression data for Paralytic Squint.

Pathways for Paralytic Squint

Pathways related to Paralytic Squint according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.04 HCK PRNP

GO Terms for Paralytic Squint

Cellular components related to Paralytic Squint according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 dendrite GO:0030425 8.92 EPHA4 GABBR1 PRNP TUBB3

Biological processes related to Paralytic Squint according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 motor neuron axon guidance GO:0008045 8.96 CHN1 EPHA4
2 regulation of axonogenesis GO:0050770 8.62 CHN1 EPHA4

Molecular functions related to Paralytic Squint according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 ephrin receptor binding GO:0046875 8.62 CHN1 EPHA4

Sources for Paralytic Squint

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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