MCID: PRN010
MIFTS: 23

Paranoid Personality Disorder malady

Category: Mental diseases

Aliases & Classifications for Paranoid Personality Disorder

About this section

Aliases & Descriptions for Paranoid Personality Disorder:

Name: Paranoid Personality Disorder 11 38 13 67

Classifications:



External Ids:

Disease Ontology11 DOID:10938
ICD1029 F60.0
ICD9CM31 301.0
MeSH38 D010260
NCIt44 C92630

Summaries for Paranoid Personality Disorder

About this section
Disease Ontology:11 A personality disorder that is characterized by paranoia and a pervasive, long-standing suspiciousness and generalized mistrust of others.

MalaCards based summary: Paranoid Personality Disorder is related to personality disorder and schizophrenia. An important gene associated with Paranoid Personality Disorder is DYNC1I1 (Dynein Cytoplasmic 1 Intermediate Chain 1). Affiliated tissues include brain.

Wikipedia:70 Paranoid personality disorder (PPD) is a mental disorder characterized by paranoia and a pervasive,... more...

Related Diseases for Paranoid Personality Disorder

About this section

Diseases related to Paranoid Personality Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1personality disorder10.3
2schizophrenia9.9
3hypo- and hypermelanotic cutaneous macules-retarded growth-intellectual disability syndrome9.8DLX5, DYNC1I1
4brain injury9.7
5hyperphalangy9.5DLX5, DYNC1I1
6intracranial aneurysm8.5DLX5, DYNC1I1, LBR, SPRN

Comorbidity relations with Paranoid Personality Disorder via Phenotypic Disease Network (PDN):


Major Depressive Disorder and Accelerated Response to Antidepressant Drug TreatmentSchizophreniform Disorder
Paranoid SchizophreniaAcute Cystitis
Delusional Disorder

Graphical network of diseases related to Paranoid Personality Disorder:



Diseases related to paranoid personality disorder

Symptoms for Paranoid Personality Disorder

About this section

Drugs & Therapeutics for Paranoid Personality Disorder

About this section

Drugs for Paranoid Personality Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 15)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Olanzapineapproved, investigationalPhase 3395132539-06-14585
Synonyms:
132539-06-1
2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)benzodiazepine
2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine
2-methyl-4-(4-methyl-1-piperazinyl)-10 H -thieno[2,3- b ] [1,5]benzodiazepine
2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine
2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
2-methyl-4-(4-methylpiperazin-1-yl)-5H-thieno[2,3-b][1,5]benzodiazepine
2-methyl-4-(4-methylpiperazin-1-yl)-5H-thieno[3,2-c][1,5]benzodiazepine
AC-665
AC1L1IHS
AKOS000282888
ALKS-7921
BIDD:GT0332
BIDD:PXR0138
Bio-0169
C07322
C076029
C17H20N4S
CHEBI:7735
CHEMBL715
CID4585
CPD000466345
D00454
DB00334
Eli Lilly brand of olanzapine
HMS2051H05
HMS2089M04
HMS2093I04
I06-0784
InChI=1/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H
InChI=1/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3
Jsp001969
KS-1090
L000455
L005958
LS-152313
LY 170053
LY-170052
 
LY-170053
Lanzac
Lilly brand of olanzapine
MLS000759457
MLS001165781
MLS001195646
MLS001424057
Midax
MolPort-002-885-845
MolPort-003-666-569
MolPort-005-977-341
NCGC00096077-01
NCGC00096077-03
NCGC00096077-04
Olansek
Olanzapin
Olanzapina
Olanzapine
Olanzapine (JAN/USAN/INN)
Olanzapine (OLA)
Olanzapine [USAN:INN]
Olanzapinum
S2493_Selleck
SAM001246652
SMR000466345
SPECTRUM1505024
STK634338
Symbyax
TL8000772
UNII-N7U69T4SZR
Zalasta
Zydis
Zyprexa
Zyprexa (TN)
Zyprexa Intramuscular
Zyprexa Velotab
Zyprexa Zydis
olanzapina
olanzapine
olanzapinum
2
SerotoninPhase 3356650-67-95202
Synonyms:
3-(2-Aminoethyl)-1H-indol-5-ol
3-(2-Aminoethyl)indol-5-ol
3-(b-Aminoethyl)-5-hydroxyindole
5-HT
5-HTA
5-Hydroxy-3-(b-aminoethyl)indole
 
5-Hydroxy-tryptamine
5-Hydroxyltryptamine
5-Hydroxytriptamine
5-Hydroxytryptamine
Antemovis
DS substance
Enteramin
Enteramine
3Psychotropic DrugsPhase 36279
4Serotonin AgentsPhase 33102
5Serotonin Uptake InhibitorsPhase 31570
6Tranquilizing AgentsPhase 34164
7Peripheral Nervous System AgentsPhase 322776
8AntiemeticsPhase 33888
9Central Nervous System DepressantsPhase 312806
10Autonomic AgentsPhase 39774
11Antipsychotic AgentsPhase 32359
12Gastrointestinal AgentsPhase 38109
13Neurotransmitter AgentsPhase 317734
14Neurotransmitter Uptake InhibitorsPhase 33464
15
Silicon947440-21-34082203
Synonyms:
Si
 
Silica
Silicate
Silicic acid

Interventional clinical trials:

idNameStatusNCT IDPhase
1Efficacy and Safety of Olanzapine in Patients With Borderline Personality DisorderCompletedNCT00088036Phase 3
2Personality Pathology and Cerebral Processing in Eating DisordersRecruitingNCT02980120

Search NIH Clinical Center for Paranoid Personality Disorder


Cochrane evidence based reviews: paranoid personality disorder

Genetic Tests for Paranoid Personality Disorder

About this section

Anatomical Context for Paranoid Personality Disorder

About this section

MalaCards organs/tissues related to Paranoid Personality Disorder:

35
Brain

Animal Models for Paranoid Personality Disorder or affiliated genes

About this section

Publications for Paranoid Personality Disorder

About this section

Articles related to Paranoid Personality Disorder:

(show all 15)
idTitleAuthorsYear
1
Paranoid personality disorder in the United States: the role of race, illicit drug use, and income. (25176118)
2014
2
The relative impact of socioeconomic status and childhood trauma on Black-White differences in paranoid personality disorder symptoms. (24661172)
2014
3
Paranoid personality disorder and the schizophrenia spectrum-Where to draw the line? (24343968)
2013
4
Paranoid personality disorder and organic brain injury: a case report. (23487234)
2013
5
Paranoid personality disorder. (22928850)
2013
6
Psychopharmacological treatment and course in paranoid personality disorder: a case series. (23820335)
2013
7
Treatment of Paranoid Personality Disorder with Cognitive Analytic Therapy: A Mixed Methods Single Case Experimental Design. (23733739)
2013
8
Varenicline precipitating psychosis in a patient with no previous psychiatric history: a case report of a Spanish patient who was later diagnosed with paranoid personality disorder. (22182460)
2012
9
Pharmacological interventions for paranoid personality disorder. (25267902)
2011
10
Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, paranoid personality disorder diagnosis: a unitary or a two-dimensional construct? (19840591)
2009
11
Examining the developmental history of child maltreatment, peer relations, and externalizing problems among adolescents with symptoms of paranoid personality disorder. (19825263)
2009
12
Impoverished dialogical relationship patterns in paranoid personality disorder. (16370132)
2005
13
Schizotypal and paranoid personality disorder in the relatives of patients with schizophrenia and affective disorders: a review. (8297808)
1993
14
Paranoid personality disorder: a synthesis of developmental, dynamic, and descriptive features. (2183636)
1990
15
Genetic relationship between paranoid personality disorder and the "schizophrenic spectrum" disorders. (7114313)
1982

Variations for Paranoid Personality Disorder

About this section

Expression for genes affiliated with Paranoid Personality Disorder

About this section
Search GEO for disease gene expression data for Paranoid Personality Disorder.

Pathways for genes affiliated with Paranoid Personality Disorder

About this section

GO Terms for genes affiliated with Paranoid Personality Disorder

About this section

Cellular components related to Paranoid Personality Disorder according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1vesicleGO:00319829.5DYNC1I1, SPRN

Sources for Paranoid Personality Disorder

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet