MCID: PRN010
MIFTS: 25

Paranoid Personality Disorder malady

Category: Mental diseases

Aliases & Classifications for Paranoid Personality Disorder

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Aliases & Descriptions for Paranoid Personality Disorder:

Name: Paranoid Personality Disorder 10 12 36 65

Classifications:



External Ids:

Disease Ontology10 DOID:10938
ICD1027 F60.0
ICD9CM29 301.0
MeSH36 D010260
NCIt42 C92630
UMLS65 C0030477

Summaries for Paranoid Personality Disorder

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Disease Ontology:10 A personality disorder that is characterized by paranoia and a pervasive, long-standing suspiciousness and generalized mistrust of others.

MalaCards based summary: Paranoid Personality Disorder is related to personality disorder and schizophrenia. An important gene associated with Paranoid Personality Disorder is SPRN (Shadow Of Prion Protein Homolog (Zebrafish)). Affiliated tissues include bone, eye and lung.

Wikipedia:68 Paranoid personality disorder (PPD) is a mental disorder characterized by paranoia and a pervasive,... more...

Related Diseases for Paranoid Personality Disorder

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Diseases related to Paranoid Personality Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1personality disorder10.4
2schizophrenia10.0
3brain injury9.9
4antisocial personality disorder9.5LBR, SPRN

Comorbidity relations with Paranoid Personality Disorder via Phenotypic Disease Network (PDN):


Major Depressive Disorder and Accelerated Response to Antidepressant Drug TreatmentSchizophreniform Disorder
Paranoid SchizophreniaAcute Cystitis
Delusional Disorder

Symptoms for Paranoid Personality Disorder

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Drugs & Therapeutics for Paranoid Personality Disorder

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Drugs for Paranoid Personality Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Olanzapineapproved, investigationalPhase 3379132539-06-14585
Synonyms:
132539-06-1
2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)benzodiazepine
2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine
2-methyl-4-(4-methyl-1-piperazinyl)-10 H -thieno[2,3- b ] [1,5]benzodiazepine
2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine
2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
2-methyl-4-(4-methylpiperazin-1-yl)-5H-thieno[2,3-b][1,5]benzodiazepine
2-methyl-4-(4-methylpiperazin-1-yl)-5H-thieno[3,2-c][1,5]benzodiazepine
AC-665
AC1L1IHS
AKOS000282888
ALKS-7921
BIDD:GT0332
BIDD:PXR0138
Bio-0169
C07322
C076029
C17H20N4S
CHEBI:7735
CHEMBL715
CID4585
CPD000466345
D00454
DB00334
Eli Lilly brand of olanzapine
HMS2051H05
HMS2089M04
HMS2093I04
I06-0784
InChI=1/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H
InChI=1/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3
Jsp001969
KS-1090
L000455
L005958
LS-152313
LY 170053
LY-170052
LY-170053
 
Lanzac
Lilly brand of olanzapine
MLS000759457
MLS001165781
MLS001195646
MLS001424057
Midax
MolPort-002-885-845
MolPort-003-666-569
MolPort-005-977-341
NCGC00096077-01
NCGC00096077-03
NCGC00096077-04
Olansek
Olanzapin
Olanzapina
Olanzapine
Olanzapine (JAN/USAN/INN)
Olanzapine (OLA)
Olanzapine [USAN:INN]
Olanzapine pamoate
Olanzapinum
S2493_Selleck
SAM001246652
SMR000466345
SPECTRUM1505024
STK634338
Symbyax
TL8000772
UNII-N7U69T4SZR
Zalasta
Zydis
Zyprexa
Zyprexa (TN)
Zyprexa Intramuscular
Zyprexa Velotab
Zyprexa Zydis
olanzapina
olanzapine
olanzapinum
2
SerotoninPhase 3314750-67-95202
Synonyms:
3-(2-Aminoethyl)-1H-indol-5-ol
3-(2-Aminoethyl)indol-5-ol
3-(b-Aminoethyl)-5-hydroxyindole
5-HT
5-HTA
5-Hydroxy-3-(b-aminoethyl)indole
 
5-Hydroxy-tryptamine
5-Hydroxyltryptamine
5-Hydroxytriptamine
5-Hydroxytryptamine
Antemovis
DS substance
Enteramin
Enteramine
3Psychotropic DrugsPhase 35501
4Serotonin AgentsPhase 32668
5Serotonin Uptake InhibitorsPhase 31369
6Tranquilizing AgentsPhase 33597
7Peripheral Nervous System AgentsPhase 318510
8AntiemeticsPhase 33213
9Central Nervous System DepressantsPhase 310016
10Gastrointestinal AgentsPhase 36401
11Neurotransmitter AgentsPhase 314795
12Neurotransmitter Uptake InhibitorsPhase 32857
13Antipsychotic AgentsPhase 32130

Interventional clinical trials:

idNameStatusNCT IDPhase
1Efficacy and Safety of Olanzapine in Patients With Borderline Personality DisorderCompletedNCT00088036Phase 3

Search NIH Clinical Center for Paranoid Personality Disorder


Cochrane evidence based reviews: paranoid personality disorder

Genetic Tests for Paranoid Personality Disorder

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Anatomical Context for Paranoid Personality Disorder

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MalaCards organs/tissues related to Paranoid Personality Disorder:

33
Bone, Eye, Lung, Ovary, Pituitary, Myeloid, Brain

Animal Models for Paranoid Personality Disorder or affiliated genes

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Publications for Paranoid Personality Disorder

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Articles related to Paranoid Personality Disorder:

(show all 15)
idTitleAuthorsYear
1
Paranoid personality disorder in the United States: the role of race, illicit drug use, and income. (25176118)
2014
2
The relative impact of socioeconomic status and childhood trauma on Black-White differences in paranoid personality disorder symptoms. (24661172)
2014
3
Paranoid personality disorder and the schizophrenia spectrum-Where to draw the line? (24343968)
2013
4
Paranoid personality disorder and organic brain injury: a case report. (23487234)
2013
5
Paranoid personality disorder. (22928850)
2013
6
Treatment of Paranoid Personality Disorder with Cognitive Analytic Therapy: A Mixed Methods Single Case Experimental Design. (23733739)
2013
7
Psychopharmacological treatment and course in paranoid personality disorder: a case series. (23820335)
2013
8
Varenicline precipitating psychosis in a patient with no previous psychiatric history: a case report of a Spanish patient who was later diagnosed with paranoid personality disorder. (22182460)
2012
9
Pharmacological interventions for paranoid personality disorder. (25267902)
2011
10
Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, paranoid personality disorder diagnosis: a unitary or a two-dimensional construct? (19840591)
2009
11
Examining the developmental history of child maltreatment, peer relations, and externalizing problems among adolescents with symptoms of paranoid personality disorder. (19825263)
2009
12
Impoverished dialogical relationship patterns in paranoid personality disorder. (16370132)
2005
13
Schizotypal and paranoid personality disorder in the relatives of patients with schizophrenia and affective disorders: a review. (8297808)
1993
14
Paranoid personality disorder: a synthesis of developmental, dynamic, and descriptive features. (2183636)
1990
15
Genetic relationship between paranoid personality disorder and the "schizophrenic spectrum" disorders. (7114313)
1982

Variations for Paranoid Personality Disorder

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Expression for genes affiliated with Paranoid Personality Disorder

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Search GEO for disease gene expression data for Paranoid Personality Disorder.

Pathways for genes affiliated with Paranoid Personality Disorder

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GO Terms for genes affiliated with Paranoid Personality Disorder

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Sources for Paranoid Personality Disorder

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet