MCID: PRN010
MIFTS: 24

Paranoid Personality Disorder malady

Categories: Mental diseases

Aliases & Classifications for Paranoid Personality Disorder

Aliases & Descriptions for Paranoid Personality Disorder:

Name: Paranoid Personality Disorder 12 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:10938
ICD10 33 F60.0
ICD9CM 35 301.0
MeSH 42 D010260
NCIt 47 C92630
UMLS 69 C0030477

Summaries for Paranoid Personality Disorder

Disease Ontology : 12 A personality disorder that is characterized by paranoia and a pervasive, long-standing suspiciousness and generalized mistrust of others.

MalaCards based summary : Paranoid Personality Disorder is related to personality disorder and spondylocostal dysostosis 3. An important gene associated with Paranoid Personality Disorder is DYNC1I1 (Dynein Cytoplasmic 1 Intermediate Chain 1). The drugs Olanzapine and Serotonin have been mentioned in the context of this disorder. Affiliated tissues include brain.

Wikipedia : 71 Paranoid personality disorder (PPD) is a mental disorder characterized by paranoia and a pervasive,... more...

Related Diseases for Paranoid Personality Disorder

Diseases related to Paranoid Personality Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

id Related Disease Score Top Affiliating Genes
1 personality disorder 10.3
2 spondylocostal dysostosis 3 9.9 DLX5 SEM1
3 schizophrenia 9.9
4 congenital absence of both lower leg and foot 9.9 DLX5 SEM1
5 3mc syndrome 1 9.8 DLX5 SEM1
6 angiocentric glioma 9.8 DLX5 DYNC1I1 SEM1
7 congenital absence/hypoplasia of thumb 9.8 DLX5 DYNC1I1 SEM1
8 brain injury 9.7
9 alpha thalassemia-x-linked intellectual disability syndrome 9.7 DLX5 DYNC1I1 SEM1
10 tongue disease 9.3 DLX5 DYNC1I1 LBR SEM1 SPRN

Comorbidity relations with Paranoid Personality Disorder via Phenotypic Disease Network (PDN):


Acute Cystitis Delusional Disorder
Paranoid Schizophrenia Schizophreniform Disorder

Graphical network of the top 20 diseases related to Paranoid Personality Disorder:



Diseases related to Paranoid Personality Disorder

Symptoms & Phenotypes for Paranoid Personality Disorder

Drugs & Therapeutics for Paranoid Personality Disorder

Drugs for Paranoid Personality Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 15)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Olanzapine Approved, Investigational Phase 3 132539-06-1 4585
2
Serotonin Phase 3 50-67-9 5202
3 Serotonin Agents Phase 3
4 Serotonin Uptake Inhibitors Phase 3
5 Gastrointestinal Agents Phase 3
6 Neurotransmitter Agents Phase 3
7 Neurotransmitter Uptake Inhibitors Phase 3
8 Tranquilizing Agents Phase 3
9 Peripheral Nervous System Agents Phase 3
10 Antiemetics Phase 3
11 Psychotropic Drugs Phase 3
12 Antipsychotic Agents Phase 3
13 Autonomic Agents Phase 3
14 Central Nervous System Depressants Phase 3
15
Silicon 7440-21-3 4082203

Interventional clinical trials:


id Name Status NCT ID Phase
1 Efficacy and Safety of Olanzapine in Patients With Borderline Personality Disorder Completed NCT00088036 Phase 3
2 Personality Pathology and Cerebral Processing in Eating Disorders Recruiting NCT02980120

Search NIH Clinical Center for Paranoid Personality Disorder

Cochrane evidence based reviews: paranoid personality disorder

Genetic Tests for Paranoid Personality Disorder

Anatomical Context for Paranoid Personality Disorder

MalaCards organs/tissues related to Paranoid Personality Disorder:

39
Brain

Publications for Paranoid Personality Disorder

Articles related to Paranoid Personality Disorder:

(show all 15)
id Title Authors Year
1
The relative impact of socioeconomic status and childhood trauma on Black-White differences in paranoid personality disorder symptoms. ( 24661172 )
2014
2
Paranoid personality disorder in the United States: the role of race, illicit drug use, and income. ( 25176118 )
2014
3
Treatment of Paranoid Personality Disorder with Cognitive Analytic Therapy: A Mixed Methods Single Case Experimental Design. ( 23733739 )
2013
4
Paranoid personality disorder and the schizophrenia spectrum-Where to draw the line? ( 24343968 )
2013
5
Paranoid personality disorder and organic brain injury: a case report. ( 23487234 )
2013
6
Psychopharmacological treatment and course in paranoid personality disorder: a case series. ( 23820335 )
2013
7
Paranoid personality disorder. ( 22928850 )
2013
8
Varenicline precipitating psychosis in a patient with no previous psychiatric history: a case report of a Spanish patient who was later diagnosed with paranoid personality disorder. ( 22182460 )
2012
9
Pharmacological interventions for paranoid personality disorder. ( 25267902 )
2011
10
Examining the developmental history of child maltreatment, peer relations, and externalizing problems among adolescents with symptoms of paranoid personality disorder. ( 19825263 )
2009
11
Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, paranoid personality disorder diagnosis: a unitary or a two-dimensional construct? ( 19840591 )
2009
12
Impoverished dialogical relationship patterns in paranoid personality disorder. ( 16370132 )
2005
13
Schizotypal and paranoid personality disorder in the relatives of patients with schizophrenia and affective disorders: a review. ( 8297808 )
1993
14
Paranoid personality disorder: a synthesis of developmental, dynamic, and descriptive features. ( 2183636 )
1990
15
Genetic relationship between paranoid personality disorder and the "schizophrenic spectrum" disorders. ( 7114313 )
1982

Variations for Paranoid Personality Disorder

Expression for Paranoid Personality Disorder

Search GEO for disease gene expression data for Paranoid Personality Disorder.

Pathways for Paranoid Personality Disorder

GO Terms for Paranoid Personality Disorder

Cellular components related to Paranoid Personality Disorder according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 vesicle GO:0031982 8.62 DYNC1I1 SPRN

Biological processes related to Paranoid Personality Disorder according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 positive regulation of canonical Wnt signaling pathway GO:0090263 8.62 DLX5 SEM1

Sources for Paranoid Personality Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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