MCID: PRT002
MIFTS: 52

Paratyphoid Fever malady

Categories: Infectious diseases, Rare diseases, Gastrointestinal diseases

Aliases & Classifications for Paratyphoid Fever

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Sources:
11Disease Ontology, 13DISEASES, 52Orphanet, 37MeSH, 66UMLS, 28ICD10, 30ICD9CM, 43NCIt, 29ICD10 via Orphanet, 60SNOMED-CT
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Aliases & Descriptions for Paratyphoid Fever:

Name: Paratyphoid Fever 11 13 52 37 66
Paratyphoid B Fever 11 66
Paratyphoid C Fever 11 66
Paratyphoid Fever B 11
Paratyphoid a Fever 11
Paratyphoid Fever C 11
 
Paratyphoid Fever a 11
Paratyphoid a 11
Paratyphoid B 11
Paratyphoid C 11
Paratyphoid 11

Characteristics:

Orphanet epidemiological data:

52
paratyphoid fever:
Inheritance: Not applicable

Classifications:



Summaries for Paratyphoid Fever

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Disease Ontology:11 A primary bacterial infectious disease that results in infection located in intestine, has material basis in salmonella enterica subsp enterica serovar paratyphi a, b or c, which are transmitted by ingestion of contaminated food. the infection has symptom fever, has symptom headache, has symptom abdominal pain, has symptom malaise, has symptom anorexia, has symptom constipation, has symptom rosy spots on the central body, has symptom non productive cough (in early stage of illness), has symptom bradycardia, and has symptom hepatosplenomegaly.

MalaCards based summary: Paratyphoid Fever, also known as paratyphoid b fever, is related to typhoid fever and familial dupuytren contracture, and has symptoms including fever, headache and abdominal pain. An important gene associated with Paratyphoid Fever is IFNGR1 (Interferon Gamma Receptor 1), and among its related pathways are Monoamine Transport and Legionellosis. Affiliated tissues include intestine, skin and prostate, and related mouse phenotypes are endocrine/exocrine gland and skeleton.

Wikipedia:69 Paratyphoid fever, also known simply as paratyphoid, is a bacterial infection caused by one of the three... more...

Related Diseases for Paratyphoid Fever

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Diseases related to Paratyphoid Fever via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 79)
idRelated DiseaseScoreTop Affiliating Genes
1typhoid fever11.2
2familial dupuytren contracture10.4CASP1, IL1R1
3ethmoid sinus adenoid cystic carcinoma10.4IFNGR1, TNF
4warm antibody hemolytic anemia10.4IL1R1, TNF
5mixed connective tissue disease10.3IL1R1, TNF
6oropharynx cancer10.3IL1R1, TNF
7hypospadias10.3IFNGR1, TNF
8uterine corpus endometrial stromal sarcoma10.3IL1R1, TNF
9keloids10.3IL1R1, TNF
10radioulnar synostosis retinal pigment abnormalities10.3IL1R1, TNFRSF1A
11leukoplakia10.3IL1R1, TNF
12multiple sclerosis 510.3TNF, TNFRSF1A
13cerebral atherosclerosis10.3TNF, TNFRSF1A
14elane-related neutropenia10.2TNF, TNFRSF1A
15spondylohypoplasia, arthrogryposis and popliteal pterygium10.2TNF, TNFRSF1A
16nasopharyngitis10.2CASP1, TNF
17fetal erythroblastosis10.2TNF, TNFRSF1A
18gait apraxia10.2TNF, TNFRSF1A
19salpingitis10.2TNF, TNFRSF1A
20nephrosclerosis10.2TNF, TNFRSF1A
21achilles bursitis10.1TNF, TNFRSF1A
22benign peritoneal mesothelioma10.1TNF, TNFRSF1A
23alopecia10.1TNF, TNFRSF1A
24keratosis10.1IFNGR1, TNF
25dysentery10.0
26polyradiculoneuropathy10.0IL1A, IL1R1
27pulmonary systemic sclerosis10.0IL1R1, TNF
28askin's tumor10.0IFNGR1, IL1A
29small intestine lymphoma10.0IL1A, TNF
30cutaneous porphyria10.0CASP1, IFNGR1, TNF
31mixed lacrimal gland cancer10.0IFNGR1, TNF
32epstein-barr virus hepatitis10.0IL1A, TNF
33rectosigmoid junction neoplasm9.9IL1A, TNF
34familial cold-induced inflammatory syndrome 19.9CASP1, IL1R1, TNFRSF1A
35sterility due to immotile flagella9.9IL1A, TNF
36cinca syndrome9.9CASP1, IL1R1, TNFRSF1A
37muckle-wells syndrome9.9CASP1, IL1R1, TNFRSF1A
38papillary transitional carcinoma9.9IL1A, TNF
39orbital lymphangioma9.9IL1A, TNF
40pseudoretinitis pigmentosa9.9IL1A, TNF
41atrichia with papular lesions9.9IL1A, TNF
42hepatitis9.9
43hepatitis b9.9
44ileitis9.9
45nephrotic syndrome9.9
46hepatitis a9.9
47biliary atresia9.9
48purpura9.9
49appendicitis9.9
50duodenitis9.9

Graphical network of the top 20 diseases related to Paratyphoid Fever:



Diseases related to paratyphoid fever

Symptoms for Paratyphoid Fever

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Symptoms:

 11 (show all 10)
  • fever
  • headache
  • abdominal pain
  • malaise
  • anorexia
  • constipation
  • rosy spots on the central body
  • non productive cough (in early stage of illness)
  • bradycardia
  • hepatosplenomegaly

Drugs & Therapeutics for Paratyphoid Fever

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Drugs for Paratyphoid Fever (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1LecithinNutraceuticalPhase 1, Phase 268

Interventional clinical trials:

(show all 11)
idNameStatusNCT IDPhase
1Evaluation of the Vi Polysaccharide Vaccine Against Typhoid FeverCompletedNCT00125008Phase 4
2Introduction of the Vi Polysaccharide Typhoid Vaccine in Hue City, Central VietnamCompletedNCT00131820Phase 4
3Typhoid Vi Vaccine Effectiveness in Hechi, Guangxi, ChinaCompletedNCT00131833Phase 4
4Combined Vi Vaccination and Health Education Program on the Burden of Typhoid in ChildhoodCompletedNCT00125047Phase 4
5TY800 Dose Escalation (Typhoid)CompletedNCT00269295Phase 1, Phase 2
6Safety and Efficacy Study of Mix Vaccine in Prostate Carcinoma PatientCompletedNCT02338700Phase 1, Phase 2
7Safety and Efficacy Study of Mix Vaccine in Breast Carcinoma PatientCompletedNCT02338804Phase 1, Phase 2
8Safety and Efficacy Study of Mix Vaccine in Hepatocyte Carcinoma PatientCompletedNCT02338778Phase 1, Phase 2
9Safety and Efficacy Study of Mix Vaccine in Pancreatic Carcinoma PatientCompletedNCT02338752Phase 1, Phase 2
10Investigating Enteric Fever - Salmonella Typhi and Paratyphi Challenge StudyRecruitingNCT02192008
11Understanding Paratyphoid InfectionActive, not recruitingNCT02100397

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Cochrane evidence based reviews: paratyphoid fever

Genetic Tests for Paratyphoid Fever

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Anatomical Context for Paratyphoid Fever

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MalaCards organs/tissues related to Paratyphoid Fever:

34
Skin, Prostate, Breast, Testes, Bone, Bone marrow

FMA organs/tissues related to Paratyphoid Fever:

17
Intestine

Animal Models for Paratyphoid Fever or affiliated genes

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MGI Mouse Phenotypes related to Paratyphoid Fever:

39 (show all 11)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053798.1CASP1, IFNGR1, IL1R1, TNF, TNFRSF1A
2MP:00053908.0IFNGR1, IL1R1, PARK2, TNF, TNFRSF1A
3MP:00053847.9CASP1, IFNGR1, IL1R1, PARK2, TNF, TNFRSF1A
4MP:00053877.8CASP1, IFNGR1, IL1A, IL1R1, TNF, TNFRSF1A
5MP:00020067.7CASP1, IFNGR1, IL1A, IL1R1, TNF, TNFRSF1A
6MP:00053977.6CASP1, IFNGR1, IL1A, IL1R1, TNF, TNFRSF1A
7MP:00036317.6CASP1, IFNGR1, IL1R1, PARK2, TNF, TNFRSF1A
8MP:00107717.2CASP1, IFNGR1, IL1A, IL1R1, PARK2, TNF
9MP:00053856.7CASP1, IFNGR1, IL1A, IL1R1, PARK2, TNF
10MP:00053766.4CASP1, IFNGR1, IL1A, IL1R1, PARK2, TNF

Publications for Paratyphoid Fever

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Articles related to Paratyphoid Fever:

(show top 50)    (show all 132)
idTitleAuthorsYear
1
Psychosis in paratyphoid fever - a case report from Australia. (24820292)
2014
2
Recurrent paratyphoid fever A co-infected with hepatitis A reactivated chronic hepatitis B. (24884719)
2014
3
Study of clinical profile and antibiotic sensitivity in paratyphoid Fever cases admitted at teaching hospital in South India. (24479019)
2012
4
Typhoid and paratyphoid fever - prevention in travellers. (21301658)
2010
5
Study on blood cultures and bacteria counts in the blood of paratyphoid fever A patients. (19526258)
2009
6
Fluoroquinolones for treating typhoid and paratyphoid fever (enteric fever). (18843659)
2008
7
Polymorphisms in proinflammatory genes and susceptibility to typhoid fever and paratyphoid fever. (17477815)
2007
8
PARK2/PACRG polymorphisms and susceptibility to typhoid and paratyphoid fever. (16734611)
2006
9
Paratyphoid fever in Vellore, South India. (16105360)
2005
10
Typhoid and paratyphoid fever in travellers. (16183516)
2005
11
Risk factors for typhoid and paratyphoid fever in Jakarta, Indonesia. (15173152)
2004
12
Typhoid and paratyphoid fever: a 10-year retrospective study of 41 cases in a Parisian hospital. (11726293)
2001
13
Oral administration of fluoroquinolones in the treatment of typhoid fever and paratyphoid fever in Japan. (11197787)
2000
14
Typhoid and paratyphoid fever in south-eastern Sydney, 1992-1997. (11022389)
2000
15
Paratyphoid fever due to Salmonella enterica serotype Paratyphi A. (9284393)
1997
16
A relapse of paratyphoid fever after treatment with ciprofloxacin in a child with congenital biliary atresia. (9183498)
1997
17
Monoclonal antibodies against protein antigens of salmonellae causing paratyphoid fever and their diagnostic application. (7488347)
1995
18
Paratyphoid fever presenting with renal failure and nephrotic syndrome. (2517555)
1989
19
Typhoid and paratyphoid fever. (115625)
1979
20
Influence of chloramphenicol and ampicillin on antibody response in typhoid-paratyphoid fever. (4984110)
1970
21
A comparative trial of furazolidone and chloramphenicol in typhoid and paratyphoid fever. (4995053)
1970
22
COMPARISON OF AMPICILLIN AND CHLORAMPHENICOL IN TREATMENT OF PARATYPHOID FEVER. (14072634)
1964
23
Paratyphoid Fever from Frozen Chinese Eggs. (20789773)
1963
24
Acute ileitis with ulceration and perforation due to paratyphoid fever; report of eighty-five cases. (13399825)
1957
25
Typhoid and paratyphoid fever; report of six cases with one death. (13361260)
1956
26
Second attack of paratyphoid fever. (13276681)
1956
27
PARATYPHOID fever and cream cakes. (13094092)
1953
28
The measurement of the duration of infection in paratyphoid fever. (13118154)
1953
29
Paratyphoid fever and bakers' confectionery; an analysis of an epidemic in South Wales, 1952. (13099191)
1953
30
Dissemination of paratyphoid fever from a bakery. (14824638)
1951
31
Chloromycetin in typhoid and paratyphoid fever. (14794145)
1950
32
Thrombocytopenic purpura complicating typhoid and paratyphoid fever. (18141777)
1949
33
A difficulty experienced in the bacteriological diagnosis of paratyphoid fever in cases treated with sulphonamides. (18130255)
1949
34
An outbreak of paratyphoid fever in Edmonton, Alta. (18894973)
1948
35
Field investigation of paratyphoid fever with typing of Salm. paratyphi B by means of Vi bacteriophage. (20262099)
1947
36
Paratyphoid fever. (20296482)
1946
37
3 cases of skeletal changes round the knee joint in paratyphoid fever in infants. (20985426)
1946
38
Paratyphoid Fever in Massachusetts. (18015087)
1939
39
TWO CASES OF HAEMORRHAGIC PARATYPHOID FEVER. (20776232)
1931
40
Paratyphoid Fever and Aertrycke Enteritis in Aberdeen-a Contrast. (20474903)
1926
41
Discussion on Paratyphoid Fever. (19979288)
1916
42
DISCUSSION ON PARATYPHOID FEVER. (19979278)
1916
43
Discussion on Paratyphoid Fever. (19979286)
1916
44
Discussion on Paratyphoid Fever. (19979289)
1916
45
DISCUSSION ON PARATYPHOID FEVER. (19979279)
1916
46
DISCUSSION ON PARATYPHOID FEVER. (19979292)
1916
47
COMBINED PREVENTIVE INOCULATION AGAINST TYPHOID AND PARATYPHOID FEVER AND BACILLARY DYSENTERY. (20767977)
1916
48
Discussion on Paratyphoid Fever. (19979285)
1916
49
Preliminary Note ON THE CLINICAL ASPECTS AND DIAGNOSIS OF PARATYPHOID FEVER. (20767886)
1915
50
Report of an Epidemic of Probable Paratyphoid Fever. (19599427)
1910

Variations for Paratyphoid Fever

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Expression for genes affiliated with Paratyphoid Fever

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Search GEO for disease gene expression data for Paratyphoid Fever.

Pathways for genes affiliated with Paratyphoid Fever

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Pathways related to Paratyphoid Fever according to GeneCards Suite gene sharing:

(show all 50)
idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.5IL1R1, TNF
29.5CASP1, TNF
39.5CASP1, TNF
4
Show member pathways
9.4TNF, TNFRSF1A
59.4TNF, TNFRSF1A
69.4TNF, TNFRSF1A
79.4TNF, TNFRSF1A
89.4TNF, TNFRSF1A
99.4TNF, TNFRSF1A
109.2IL1A, IL1R1
119.2CASP1, IL1A
12
Show member pathways
9.2IFNGR1, IL1R1, TNF
139.1IL1A, TNF
149.1IL1A, TNF
159.1IL1A, TNF
16
Show member pathways
9.1IFNGR1, TNF, TNFRSF1A
179.1IFNGR1, TNF, TNFRSF1A
18
Show member pathways
9.1IFNGR1, TNF, TNFRSF1A
199.0IL1R1, TNF, TNFRSF1A
209.0IL1R1, TNF, TNFRSF1A
219.0IL1R1, TNF, TNFRSF1A
22
Show member pathways
9.0CASP1, TNF, TNFRSF1A
23
Show member pathways
9.0CASP1, TNF, TNFRSF1A
24
Show member pathways
9.0CASP1, TNF, TNFRSF1A
25
Show member pathways
9.0CASP1, TNF, TNFRSF1A
26
Show member pathways
8.8CASP1, IFNGR1, IL1A
27
Show member pathways
8.8CASP1, IL1A, IL1R1
288.7IL1A, IL1R1, TNF
298.7IL1A, IL1R1, TNF
308.7CASP1, IL1A, TNF
31
Show member pathways
8.6IL1A, TNF, TNFRSF1A
32
Show member pathways
8.6CASP1, IL1R1, TNF, TNFRSF1A
33
Show member pathways
8.3IFNGR1, IL1A, IL1R1, TNF
34
Show member pathways
8.3CASP1, IL1A, IL1R1, TNF
358.2IFNGR1, IL1A, TNF, TNFRSF1A
36
Show member pathways
8.2IFNGR1, IL1A, TNF, TNFRSF1A
378.2IL1A, IL1R1, TNF, TNFRSF1A
38
Show member pathways
8.2IL1A, IL1R1, TNF, TNFRSF1A
39
Show member pathways
8.2CASP1, IL1A, TNF, TNFRSF1A
40
Show member pathways
7.9CASP1, IFNGR1, IL1A, IL1R1, TNFRSF1A
41
Show member pathways
7.8IFNGR1, IL1A, IL1R1, TNF, TNFRSF1A
42
Show member pathways
7.8IFNGR1, IL1A, IL1R1, TNF, TNFRSF1A
437.8IFNGR1, IL1A, IL1R1, TNF, TNFRSF1A
44
Show member pathways
7.8IFNGR1, IL1A, IL1R1, TNF, TNFRSF1A
45
Show member pathways
7.8CASP1, IFNGR1, IL1A, TNF, TNFRSF1A
46
Show member pathways
7.7CASP1, IL1A, IL1R1, TNF, TNFRSF1A
47
Show member pathways
7.7CASP1, IL1A, IL1R1, TNF, TNFRSF1A
487.7CASP1, IL1A, IL1R1, TNF, TNFRSF1A
49
Show member pathways
7.4CASP1, IFNGR1, IL1A, IL1R1, TNF, TNFRSF1A
50
Show member pathways
6.7CASP1, IFNGR1, IL1A, IL1R1, PARK2, TNF

GO Terms for genes affiliated with Paratyphoid Fever

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Biological processes related to Paratyphoid Fever according to GeneCards Suite gene sharing:

(show all 24)
idNameGO IDScoreTop Affiliating Genes
1regulation of establishment of endothelial barrierGO:190314010.1TNF, TNFRSF1A
2death-inducing signaling complex assemblyGO:007155010.1TNF, TNFRSF1A
3I-kappaB kinase/NF-kappaB signalingGO:000724910.0TNF, TNFRSF1A
4establishment of protein localization to plasma membraneGO:009000210.0TNF, TNFRSF1A
5intrinsic apoptotic signaling pathway in response to DNA damageGO:000863010.0TNF, TNFRSF1A
6positive regulation of neutrophil extravasationGO:200039110.0IL1A, IL1R1
7regulation of tumor necrosis factor-mediated signaling pathwayGO:00108039.9TNF, TNFRSF1A
8positive regulation of ceramide biosynthetic processGO:20003049.9TNF, TNFRSF1A
9interleukin-1-mediated signaling pathwayGO:00704989.9IL1A, IL1R1
10defense responseGO:00069529.9TNF, TNFRSF1A
11regulation of inflammatory responseGO:00507279.8CASP1, IL1R1
12extrinsic apoptotic signaling pathway via death domain receptorsGO:00086259.8TNF, TNFRSF1A
13regulation of reactive oxygen species metabolic processGO:20003779.7PARK2, TNF
14negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:20012409.7IL1A, TNF
15positive regulation of JNK cascadeGO:00463309.6IL1A, TNF
16positive regulation of interleukin-6 productionGO:00327559.5IL1A, TNF
17positive regulation of cytokine secretionGO:00507159.2CASP1, IL1A, TNF
18regulation of autophagyGO:00105069.1CASP1, PARK2
19cytokine-mediated signaling pathwayGO:00192219.1IL1A, IL1R1, TNFRSF1A
20inflammatory responseGO:00069549.0IL1A, TNF, TNFRSF1A
21immune responseGO:00069558.8IL1A, IL1R1, TNFRSF1A
22positive regulation of gene expressionGO:00106288.7IL1A, PARK2, TNF
23positive regulation of I-kappaB kinase/NF-kappaB signalingGO:00431238.0CASP1, IL1A, PARK2, TNF, TNFRSF1A
24positive regulation of transcription from RNA polymerase II promoterGO:00459448.0IL1A, PARK2, TNF, TNFRSF1A

Sources for Paratyphoid Fever

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet