MCID: PRT002
MIFTS: 57

Paratyphoid Fever malady

Categories: Infectious diseases, Rare diseases, Gastrointestinal diseases

Aliases & Classifications for Paratyphoid Fever

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Sources:
10Disease Ontology, 12DISEASES, 51Orphanet, 36MeSH, 65UMLS, 27ICD10, 29ICD9CM, 42NCIt, 59SNOMED-CT, 28ICD10 via Orphanet
See all MalaCards sources

Aliases & Descriptions for Paratyphoid Fever:

Name: Paratyphoid Fever 10 12 51 36 65
Paratyphoid B Fever 10 65
Paratyphoid C Fever 10 65
Paratyphoid Fever B 10
Paratyphoid a Fever 10
Paratyphoid Fever C 10
 
Paratyphoid Fever a 10
Paratyphoid a 10
Paratyphoid B 10
Paratyphoid C 10
Paratyphoid 10

Classifications:



External Ids:

Disease Ontology10 DOID:3055
MeSH36 D010284
Orphanet51 443227
ICD10 via Orphanet28 A01.1, A01.2, A01.3 A01.4, more
UMLS65 C0030528, C0343375, C0343376 C0343377, more

Summaries for Paratyphoid Fever

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Disease Ontology:10 A primary bacterial infectious disease that results in infection located in intestine, has material basis in Salmonella enterica subsp enterica serovar Paratyphi A, B or C, which are transmitted by ingestion of contaminated food. The infection has symptom fever, has symptom headache, has symptom abdominal pain, has symptom malaise, has symptom anorexia, has symptom constipation, has symptom rosy spots on the central body, has symptom non productive cough (in early stage of illness), has symptom bradycardia, and has symptom hepatosplenomegaly.

MalaCards based summary: Paratyphoid Fever, also known as paratyphoid b fever, is related to typhoid fever and polyradiculopathy, and has symptoms including fever, headache and abdominal pain. An important gene associated with Paratyphoid Fever is IFNGR1 (Interferon Gamma Receptor 1), and among its related pathways are Cellular Transformation by HTLV1 and Hypertrophy Model. Affiliated tissues include intestine, skin and prostate, and related mouse phenotypes are renal/urinary system and skeleton.

Wikipedia:68 Paratyphoid fever, also known simply as paratyphoid, is a bacterial infection caused by one of the three... more...

Related Diseases for Paratyphoid Fever

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Diseases related to Paratyphoid Fever via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 63)
idRelated DiseaseScoreTop Affiliating Genes
1typhoid fever11.2
2polyradiculopathy10.3IL1A, IL1R1
3familial mediterranean fever, ad10.2CASP1, TNFRSF1A
4dysentery10.0
5waardenburg syndrome type 410.0IL1B, IL1R1
6familial colorectal cancer10.0IL1B, IL1R1
7chudley rozdilsky syndrome10.0CASP1, IL1B
8tinea capitis10.0CASP1, IL1B
9ureteral disease10.0IL1B, IL1R1
10anatomical narrow angle borderline glaucoma9.9IL1A, IL1B
11stalker chitayat syndrome9.9IL1A, IL1B
12lujo hemorrhagic fever9.9IL1A, IL1B
13rhabdoid cancer9.9IL1B, TNFRSF1A
14optic neuritis9.9IL1A, IL1B
15meningoencephalocele9.9IL1A, IL1B
16hepatitis9.9
17hepatitis b9.9
18ileitis9.9
19nephrotic syndrome9.9
20hepatitis a9.9
21biliary atresia9.9
22purpura9.9
23appendicitis9.9
24duodenitis9.9
25vasculitis9.9
26diversion colitis9.9CASP1, IL1B
27peripheral retinal degeneration9.9IL1A, IL1B
28hypoglycemic coma9.9IFNGR1, IL1B
29idiopathic spinal cord herniation9.9IL1A, IL1B
30foster-kennedy syndrome9.9IL1A, IL1B
31testicular brenner tumor9.9IL1A, IL1B
32balantidiasis9.9CASP1, IL1B
33abdominal tuberculosis9.9IL1A, IL1B
34precursor b lymphoblastic lymphoma/leukemia9.9IL1A, IL1R1, TNFRSF1A
35submandibular gland disease9.8IL1A, IL1B
36periodontal disease9.8IL1A, IL1B
37bacteremia9.8
38aortic aneurysm9.8
39aneurysm9.8
40blue color blindness9.8IL1B, TNFRSF1A
41intervertebral disc disease9.8IL1A, IL1B
42single ventricular heart9.8IL1A, IL1B
43funisitis9.8IL1A, IL1B
44granulomatous orchitis9.7IL1A, IL1B
45peritoneal mesothelioma9.7IL1B, TNFRSF1A
46porphyria9.7CASP1, IFNGR1, IL1B
47methylmalonic acidemia9.6IL1A, IL1B
48mixed mineral dust pneumoconiosis9.6IL1A, IL1B
49wells-jankovic syndrome9.6IL1B, IL1R1, TNFRSF1A
50glycoproteinosis9.5IL1A, IL1B

Graphical network of the top 20 diseases related to Paratyphoid Fever:



Diseases related to paratyphoid fever

Symptoms for Paratyphoid Fever

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Symptoms:

 10 (show all 10)
  • fever
  • headache
  • abdominal pain
  • malaise
  • anorexia
  • constipation
  • rosy spots on the central body
  • non productive cough (in early stage of illness)
  • bradycardia
  • hepatosplenomegaly

Drugs & Therapeutics for Paratyphoid Fever

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Drugs for Paratyphoid Fever (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Immunologic FactorsPhase 418483
2VaccinesPhase 4, Phase 1, Phase 26085
3Liver ExtractsPhase 1, Phase 23572
4Pharmaceutical SolutionsPhase 1, Phase 27004
5LecithinNutraceuticalPhase 1, Phase 263
6Soy BeanNutraceuticalPhase 1, Phase 2455

Interventional clinical trials:

(show all 11)
idNameStatusNCT IDPhase
1Evaluation of the Vi Polysaccharide Vaccine Against Typhoid FeverCompletedNCT00125008Phase 4
2Introduction of the Vi Polysaccharide Typhoid Vaccine in Hue City, Central VietnamCompletedNCT00131820Phase 4
3Typhoid Vi Vaccine Effectiveness in Hechi, Guangxi, ChinaCompletedNCT00131833Phase 4
4Combined Vi Vaccination and Health Education Program on the Burden of Typhoid in ChildhoodCompletedNCT00125047Phase 4
5TY800 Dose Escalation (Typhoid)CompletedNCT00269295Phase 1, Phase 2
6Safety and Efficacy Study of Mix Vaccine in Prostate Carcinoma PatientCompletedNCT02338700Phase 1, Phase 2
7Safety and Efficacy Study of Mix Vaccine in Breast Carcinoma PatientCompletedNCT02338804Phase 1, Phase 2
8Safety and Efficacy Study of Mix Vaccine in Hepatocyte Carcinoma PatientCompletedNCT02338778Phase 1, Phase 2
9Safety and Efficacy Study of Mix Vaccine in Pancreatic Carcinoma PatientCompletedNCT02338752Phase 1, Phase 2
10Investigating Enteric Fever - Salmonella Typhi and Paratyphi Challenge StudyRecruitingNCT02192008
11Understanding Paratyphoid InfectionActive, not recruitingNCT02100397

Search NIH Clinical Center for Paratyphoid Fever


Cochrane evidence based reviews: paratyphoid fever

Genetic Tests for Paratyphoid Fever

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Anatomical Context for Paratyphoid Fever

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MalaCards organs/tissues related to Paratyphoid Fever:

33
Skin, Prostate, Liver, Bone, Breast, T cells, Endothelial

FMA organs/tissues related to Paratyphoid Fever:

16
Intestine

Animal Models for Paratyphoid Fever or affiliated genes

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MGI Mouse Phenotypes related to Paratyphoid Fever:

38 (show all 11)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053679.1CASP1, IFNGR1, IL1R1, TNFRSF1A
2MP:00053907.9IFNGR1, IL1B, IL1R1, PARK2, TNFRSF1A
3MP:00020067.9CASP1, IFNGR1, IL1A, IL1B, IL1R1, TNFRSF1A
4MP:00036317.7CASP1, IFNGR1, IL1B, IL1R1, PARK2, TNFRSF1A
5MP:00053877.6CASP1, IFNGR1, IL1A, IL1B, IL1R1, TNFRSF1A
6MP:00053977.6CASP1, IFNGR1, IL1A, IL1B, IL1R1, TNFRSF1A
7MP:00107717.2CASP1, IFNGR1, IL1A, IL1B, IL1R1, PARK2
8MP:00053767.1CASP1, IFNGR1, IL1A, IL1B, IL1R1, PARK2
9MP:00053857.0CASP1, IFNGR1, IL1A, IL1B, IL1R1, PARK2

Publications for Paratyphoid Fever

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Articles related to Paratyphoid Fever:

(show top 50)    (show all 131)
idTitleAuthorsYear
1
Psychosis in paratyphoid fever - a case report from Australia. (24820292)
2014
2
Correction: The Application of the Grey Disaster Model to Forecast Epidemic Peaks of Typhoid and Paratyphoid Fever in China. (24039655)
2013
3
Typhoid and paratyphoid fever in Western Sydney Local Health District, NSW, January-June 2011. (23043747)
2012
4
Association between the incidence of typhoid and paratyphoid fever and meteorological variables in Guizhou, China. (22490402)
2012
5
Fluoroquinolones for treating typhoid and paratyphoid fever (enteric fever). (21975746)
2011
6
Burden of typhoid and paratyphoid fever in a densely populated urban community, Dhaka, Bangladesh. (20236850)
2010
7
Typhoid and paratyphoid fever - prevention in travellers. (21301658)
2010
8
Yields from blood cultures of patients with suspected paratyphoid fever A. (24031492)
2010
9
Study on blood cultures and bacteria counts in the blood of paratyphoid fever A patients. (19526258)
2009
10
Epidemiology of typhoid and paratyphoid fever hospitalizations in Spain (1997-2005). (19276655)
2009
11
Azithromycin for treating uncomplicated typhoid and paratyphoid fever (enteric fever). (18843701)
2008
12
Fluoroquinolones for treating typhoid and paratyphoid fever (enteric fever). (18843659)
2008
13
Laboratory-based surveillance of paratyphoid fever in the United States: travel and antimicrobial resistance. (18422453)
2008
14
Comparisons of predictors for typhoid and paratyphoid fever in Kolkata, India. (17935611)
2007
15
Polymorphisms in proinflammatory genes and susceptibility to typhoid fever and paratyphoid fever. (17477815)
2007
16
Typhoid and paratyphoid fever. (16125594)
2005
17
Paratyphoid fever in Vellore, South India. (16105360)
2005
18
Fluoroquinolones for treating typhoid and paratyphoid fever (enteric fever). (15846718)
2005
19
Typhoid and paratyphoid fever: a 10-year retrospective study of 41 cases in a Parisian hospital. (11726293)
2001
20
Paratyphoid fever in India: An emerging problem. (10341194)
1999
21
Paratyphoid fever due to Salmonella enterica serotype Paratyphi A. (9284393)
1997
22
A relapse of paratyphoid fever after treatment with ciprofloxacin in a child with congenital biliary atresia. (9183498)
1997
23
Monoclonal antibodies against protein antigens of salmonellae causing paratyphoid fever and their diagnostic application. (7488347)
1995
24
Cutaneous leukocytoclastic vasculitis in the rose spot of paratyphoid fever. (6807856)
1982
25
Typhoid and paratyphoid fever. (115625)
1979
26
Influence of chloramphenicol and ampicillin on antibody response in typhoid-paratyphoid fever. (4984110)
1970
27
A comparative trial of furazolidone and chloramphenicol in typhoid and paratyphoid fever. (4995053)
1970
28
COMPARISON OF AMPICILLIN AND CHLORAMPHENICOL IN TREATMENT OF PARATYPHOID FEVER. (14072634)
1964
29
AMPICILLIN IN THE TREATMENT OF PARATYPHOID FEVER--A COMPARATIVE TRIAL. (14246856)
1964
30
Paratyphoid fever traced to desiccated coconut. (13750036)
1961
31
Acute ileitis with ulceration and perforation due to paratyphoid fever; report of eighty-five cases. (13399825)
1957
32
Typhoid and paratyphoid fever; report of six cases with one death. (13361260)
1956
33
PARATYPHOID fever and cream cakes. (13094092)
1953
34
Dissemination of paratyphoid fever from a bakery. (14824638)
1951
35
Typhoid and paratyphoid fever in immunized subjects. (18147216)
1949
36
Thrombocytopenic purpura complicating typhoid and paratyphoid fever. (18141777)
1949
37
Field investigation of paratyphoid fever with typing of Salm. paratyphi B by means of Vi bacteriophage. (20262099)
1947
38
Pregnancy and typhoid, paratyphoid fever. (20246001)
1947
39
Paratyphoid fever. (20296482)
1946
40
Observations on an epidemic of paratyphoid fever in Dundee, 1941. (20475679)
1944
41
Paratyphoid fever: an epidemiological study. (20475641)
1942
42
Paratyphoid Fever and Aertrycke Enteritis in Aberdeen-a Contrast. (20474903)
1926
43
Discussion on Paratyphoid Fever. (19979288)
1916
44
DISCUSSION ON PARATYPHOID FEVER. (19979278)
1916
45
Discussion on Paratyphoid Fever. (19979286)
1916
46
Discussion on Paratyphoid Fever. (19979289)
1916
47
Discussion on Paratyphoid Fever. (19979283)
1916
48
The AEtiology and Epidemiology of Paratyphoid Fever and "Food-poisoning.". (19975429)
1911
49
Report of an Epidemic of Probable Paratyphoid Fever. (19599427)
1910
50
A Note on Paratyphoid Fever from the Public Health Standpoint. (19599793)
1903

Variations for Paratyphoid Fever

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Expression for genes affiliated with Paratyphoid Fever

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Search GEO for disease gene expression data for Paratyphoid Fever.

Pathways for genes affiliated with Paratyphoid Fever

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Pathways related to Paratyphoid Fever according to GeneCards Suite gene sharing:

(show all 41)
idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.6IFNGR1, TNFRSF1A
29.5IL1A, IL1R1
39.3IFNGR1, IL1B
4
Show member pathways
9.2IL1B, IL1R1
59.2CASP1, IL1B
69.2CASP1, IL1B
79.1IL1A, IL1B
89.1IL1A, IL1B
99.1IL1A, IL1B
109.1IL1A, IL1B
11
Show member pathways
9.1CASP1, IL1R1, TNFRSF1A
129.0IL1A, IL1R1, TNFRSF1A
13
Show member pathways
9.0CASP1, IL1A, TNFRSF1A
14
Show member pathways
8.9IFNGR1, IL1B, IL1R1
15
Show member pathways
8.8CASP1, IFNGR1, IL1B
168.7IL1B, IL1R1, TNFRSF1A
17
Show member pathways
8.7IL1A, IL1B, IL1R1
18
Show member pathways
8.7IL1A, IL1B, IL1R1
198.7IL1A, IL1B, IL1R1
208.7IL1A, IL1B, IL1R1
218.7CASP1, IL1A, IL1B
228.7CASP1, IL1A, IL1B
23
Show member pathways
8.6IL1A, IL1B, TNFRSF1A
24
Show member pathways
8.3IFNGR1, IL1A, IL1B, IL1R1
25
Show member pathways
8.3CASP1, IFNGR1, IL1A, IL1B
26
Show member pathways
8.3CASP1, IL1A, IL1B, IL1R1
27
Show member pathways
8.3CASP1, IL1A, IL1B, IL1R1
28
Show member pathways
8.2IFNGR1, IL1A, IL1B, TNFRSF1A
298.2IFNGR1, IL1A, IL1B, TNFRSF1A
30
Show member pathways
8.2IFNGR1, IL1A, IL1B, TNFRSF1A
31
Show member pathways
8.2IL1A, IL1B, IL1R1, TNFRSF1A
32
Show member pathways
7.8IFNGR1, IL1A, IL1B, IL1R1, TNFRSF1A
337.8IFNGR1, IL1A, IL1B, IL1R1, TNFRSF1A
34
Show member pathways
7.8IFNGR1, IL1A, IL1B, IL1R1, TNFRSF1A
35
Show member pathways
7.8IFNGR1, IL1A, IL1B, IL1R1, TNFRSF1A
36
Show member pathways
7.8CASP1, IFNGR1, IL1A, IL1B, TNFRSF1A
37
Show member pathways
7.7CASP1, IL1A, IL1B, IL1R1, TNFRSF1A
387.7CASP1, IL1A, IL1B, IL1R1, TNFRSF1A
39
Show member pathways
7.7CASP1, IL1A, IL1B, IL1R1, TNFRSF1A
40
Show member pathways
7.4CASP1, IFNGR1, IL1A, IL1B, IL1R1, TNFRSF1A
41
Show member pathways
6.7CASP1, IFNGR1, IL1A, IL1B, IL1R1, PARK2

GO Terms for genes affiliated with Paratyphoid Fever

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Biological processes related to Paratyphoid Fever according to GeneCards Suite gene sharing:

(show all 17)
idNameGO IDScoreTop Affiliating Genes
1interleukin-1 beta productionGO:00326119.8CASP1, IL1B
2response to ATPGO:00331989.8CASP1, IL1B
3fever generationGO:00016609.8IL1A, IL1B
4regulation of establishment of endothelial barrierGO:19031409.8IL1B, TNFRSF1A
5ovulationGO:00307289.7IL1B, IL1R1
6extrinsic apoptotic signaling pathway in absence of ligandGO:00971929.7IL1A, IL1B
7positive regulation of interleukin-2 biosynthetic processGO:00450869.7IL1A, IL1B
8negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:20012409.7IL1A, IL1B
9positive regulation of mitotic nuclear divisionGO:00458409.6IL1A, IL1B
10positive regulation of vascular endothelial growth factor productionGO:00105759.6IL1A, IL1B
11cellular response to glucose stimulusGO:00713339.5IL1B, IL1R1
12positive regulation of JNK cascadeGO:00463309.5IL1A, IL1B
13positive regulation of I-kappaB kinase/NF-kappaB signalingGO:00431239.2CASP1, IL1A, PARK2
14cellular response to mechanical stimulusGO:00712608.9CASP1, IL1B, TNFRSF1A
15cytokine-mediated signaling pathwayGO:00192218.6IL1A, IL1B, IL1R1, TNFRSF1A
16inflammatory responseGO:00069548.5IL1A, IL1B, TNFRSF1A
17signal transductionGO:00071658.5CASP1, IL1R1, PARK2, TNFRSF1A

Sources for Paratyphoid Fever

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet