MCID: PRT002
MIFTS: 52

Paratyphoid Fever malady

Categories: Infectious diseases, Rare diseases, Gastrointestinal diseases

Aliases & Classifications for Paratyphoid Fever

About this section
Sources:
10Disease Ontology, 12DISEASES, 51Orphanet, 36MeSH, 65UMLS, 27ICD10, 29ICD9CM, 42NCIt, 59SNOMED-CT, 28ICD10 via Orphanet
See all MalaCards sources

Aliases & Descriptions for Paratyphoid Fever:

Name: Paratyphoid Fever 10 12 51 36 65
Paratyphoid B Fever 10 65
Paratyphoid C Fever 10 65
Paratyphoid Fever B 10
Paratyphoid a Fever 10
Paratyphoid Fever C 10
 
Paratyphoid Fever a 10
Paratyphoid a 10
Paratyphoid B 10
Paratyphoid C 10
Paratyphoid 10

Classifications:



External Ids:

Disease Ontology10 DOID:3055
MeSH36 D010284
Orphanet51 443227
ICD10 via Orphanet28 A01.1, A01.2, A01.3 A01.4, more
UMLS65 C0030528, C0343375, C0343376 C0343377, more

Summaries for Paratyphoid Fever

About this section
Disease Ontology:10 A primary bacterial infectious disease that results in infection located in intestine, has material basis in Salmonella enterica subsp enterica serovar Paratyphi A, B or C, which are transmitted by ingestion of contaminated food. The infection has symptom fever, has symptom headache, has symptom abdominal pain, has symptom malaise, has symptom anorexia, has symptom constipation, has symptom rosy spots on the central body, has symptom non productive cough (in early stage of illness), has symptom bradycardia, and has symptom hepatosplenomegaly.

MalaCards based summary: Paratyphoid Fever, also known as paratyphoid b fever, is related to periodontal disease and typhoid fever, and has symptoms including fever, headache and abdominal pain. An important gene associated with Paratyphoid Fever is IFNGR1 (Interferon Gamma Receptor 1), and among its related pathways are Cellular Transformation by HTLV1 and Hypertrophy Model. Affiliated tissues include intestine, skin and liver, and related mouse phenotypes are renal/urinary system and skeleton.

Wikipedia:68 Paratyphoid fever, also known simply as paratyphoid, is a bacterial infection caused by one of the three... more...

Related Diseases for Paratyphoid Fever

About this section

Graphical network of the top 20 diseases related to Paratyphoid Fever:



Diseases related to paratyphoid fever

Symptoms for Paratyphoid Fever

About this section

Symptoms:

 10 (show all 10)
  • fever
  • headache
  • abdominal pain
  • malaise
  • anorexia
  • constipation
  • rosy spots on the central body
  • non productive cough (in early stage of illness)
  • bradycardia
  • hepatosplenomegaly

Drugs & Therapeutics for Paratyphoid Fever

About this section

Drugs for Paratyphoid Fever (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Immunologic FactorsPhase 418483
2VaccinesPhase 4, Phase 1, Phase 26085
3Liver ExtractsPhase 1, Phase 23572
4Pharmaceutical SolutionsPhase 1, Phase 27004
5LecithinNutraceuticalPhase 1, Phase 263
6Soy BeanNutraceuticalPhase 1, Phase 2455

Interventional clinical trials:

(show all 11)
idNameStatusNCT IDPhase
1Evaluation of the Vi Polysaccharide Vaccine Against Typhoid FeverCompletedNCT00125008Phase 4
2Introduction of the Vi Polysaccharide Typhoid Vaccine in Hue City, Central VietnamCompletedNCT00131820Phase 4
3Typhoid Vi Vaccine Effectiveness in Hechi, Guangxi, ChinaCompletedNCT00131833Phase 4
4Combined Vi Vaccination and Health Education Program on the Burden of Typhoid in ChildhoodCompletedNCT00125047Phase 4
5TY800 Dose Escalation (Typhoid)CompletedNCT00269295Phase 1, Phase 2
6Safety and Efficacy Study of Mix Vaccine in Prostate Carcinoma PatientCompletedNCT02338700Phase 1, Phase 2
7Safety and Efficacy Study of Mix Vaccine in Breast Carcinoma PatientCompletedNCT02338804Phase 1, Phase 2
8Safety and Efficacy Study of Mix Vaccine in Hepatocyte Carcinoma PatientCompletedNCT02338778Phase 1, Phase 2
9Safety and Efficacy Study of Mix Vaccine in Pancreatic Carcinoma PatientCompletedNCT02338752Phase 1, Phase 2
10Investigating Enteric Fever - Salmonella Typhi and Paratyphi Challenge StudyRecruitingNCT02192008
11Understanding Paratyphoid InfectionActive, not recruitingNCT02100397

Search NIH Clinical Center for Paratyphoid Fever


Cochrane evidence based reviews: paratyphoid fever

Genetic Tests for Paratyphoid Fever

About this section

Anatomical Context for Paratyphoid Fever

About this section

MalaCards organs/tissues related to Paratyphoid Fever:

33
Skin, Liver, Breast, Endothelial, Prostate, Bone, Heart

FMA organs/tissues related to Paratyphoid Fever:

16
Intestine

Animal Models for Paratyphoid Fever or affiliated genes

About this section

MGI Mouse Phenotypes related to Paratyphoid Fever:

38 (show all 11)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053679.1CASP1, IFNGR1, IL1R1, TNFRSF1A
2MP:00053907.9IFNGR1, IL1B, IL1R1, PARK2, TNFRSF1A
3MP:00020067.9CASP1, IFNGR1, IL1A, IL1B, IL1R1, TNFRSF1A
4MP:00036317.7CASP1, IFNGR1, IL1B, IL1R1, PARK2, TNFRSF1A
5MP:00053877.6CASP1, IFNGR1, IL1A, IL1B, IL1R1, TNFRSF1A
6MP:00053977.6CASP1, IFNGR1, IL1A, IL1B, IL1R1, TNFRSF1A
7MP:00107717.2CASP1, IFNGR1, IL1A, IL1B, IL1R1, PARK2
8MP:00053767.1CASP1, IFNGR1, IL1A, IL1B, IL1R1, PARK2
9MP:00053857.0CASP1, IFNGR1, IL1A, IL1B, IL1R1, PARK2

Publications for Paratyphoid Fever

About this section

Articles related to Paratyphoid Fever:

(show top 50)    (show all 130)
idTitleAuthorsYear
1
Homozygous familial hypercholesterolemia: phenotype rules! (26997470)
2016
2
Posterior reversible encephalopathy syndrome and stroke after intravenous immunoglobulin treatment in Miller-Fisher syndrome/Bickerstaff brain stem encephalitis overlap syndrome. (25149206)
2014
3
Clinicopathological and molecular features of malignant optic pathway glioma in an adult. (25150758)
2014
4
RP1 is a phosphorylation target of CK2 and is involved in cell adhesion. (23844040)
2013
5
Analysis of differentially expressed genes and microRNAs in alcoholic liver disease. (23337955)
2013
6
MCV and Merkel cell carcinoma: a molecular success story. (22710026)
2012
7
Local biochemical and morphological differences in human Achilles tendinopathy: a case control study. (22480275)
2012
8
Laminin-111 derived peptides AG73 and C16 regulate invadopodia activity of a human adenoid cystic carcinoma cell line. (21924264)
2011
9
ERI^ and PEA3 co-activate IL-8 expression and promote the invasion of breast cancer cells. (21266854)
2011
10
Chromogranin A as a useful neuroendocrine marker in patients with autoimmune Addison's disease. (19794299)
2010
11
Elucidation of mechanisms of the reciprocal cross talk between gonadotropin-releasing hormone and prostaglandin receptors. (20392830)
2010
12
Effect of combined angiotensin-converting enzyme and aldosterone inhibition on plasma plasminogen activator inhibitor type 1 levels in chronic hypertensive patients. (20470281)
2010
13
Ephrin A4 expression in osteosarcoma, impact on prognosis, and patient outcome. (20071790)
2010
14
Should atopy be assessed in elderly patients with respiratory symptoms suggestive of asthma? (20923338)
2010
15
Suramin inhibits the CD40-CD154 costimulatory interaction: a possible mechanism for immunosuppressive effects. (19283894)
2009
16
Auditory neuropathy: unexpectedly common in a screened newborn population. (19416324)
2009
17
Soluble interleukin-10 and transforming growth factor-beta in children with acute exacerbation of allergic asthma. (19191132)
2009
18
Cognitive dietary restraint: impact on bone, menstrual and metabolic status in young women. (18508099)
2008
19
Cognitive heterogeneity in genetically based prosopagnosia: a family study. (19334307)
2008
20
Further understanding of recombinant activated factor VII mode of action. (18544430)
2008
21
Predicting a clinical/biochemical phenotype for PKU/MHP patients with PAH gene mutations. (19062537)
2008
22
Association study between vesicle-associated membrane protein 2 gene polymorphisms and fluvoxamine response in Japanese major depressive patients. (17356306)
2006
23
Uncommon CT findings in relapsing polychondritis. (16155171)
2005
24
Effect of melatonin dosage on sleep disorder in tuberous sclerosis complex. (15791928)
2005
25
Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions. (16055061)
2005
26
Bullous Systemic Lupus Erythematosus as an Initial Manifestation of SLE. (16471470)
2005
27
Proteome study of colorectal cancer genesis and hepatic metastasis]. (15329256)
2004
28
Dominant negative signal transducer and activator of transcription 2 (STAT2) protein: stable expression blocks interferon alpha action in skin squamous cell carcinoma cells. (12748307)
2003
29
Globe conserving treatment of the only eye in bilateral retinoblastoma. (14609838)
2003
30
Kinetic determinants of agonist action at the recombinant human glycine receptor. (12679369)
2003
31
Polymorphisms of innate immunity genes and susceptibility to lymphatic filariasis. (14551607)
2003
32
Extraskeletal myxoid chondrosarcoma of the chest wall masquerading as a breast tumor. A case report. (11917595)
2002
33
Semicarbazide-sensitive amine oxidase in pre-eclampsia: no relation with markers of endothelial cell activation. (12204422)
2002
34
Hsp90 ensures the transition from the early Ca2+-dependent to the late phosphorylation-dependent activation of the endothelial nitric-oxide synthase in vascular endothelial growth factor-exposed endothelial cells. (11425855)
2001
35
Principles of appropriate antibiotic use for acute pharyngitis in adults. (11255529)
2001
36
Long acting beta-agonists versus theophylline for maintenance treatment of asthma. (10796631)
2000
37
Ocular massage in a case of central retinal artery occlusion the successful treatment of a hitherto undescribed type of embolism. (10799350)
2000
38
Failing energetics in failing hearts. (10980895)
2000
39
Inhibition of leukotriene formation by diethylcarbamazine modifies the acid-base balance in the rabbits with blast injuries of the lungs. (10518442)
1999
40
Effect of ultrasound on the production of IL-8, basic FGF and VEGF. (10346981)
1999
41
Investigations of neurotrophic inhibitors of FK506 binding protein via Monte Carlo simulations. (9767630)
1998
42
An inherited mutation associated with functional deficiency of the alpha-subunit of the guanine nucleotide-binding protein Gs in pseudo- and pseudopseudohypoparathyroidism. (9506752)
1998
43
E1A represses apolipoprotein AI enhancer activity in liver cells through a pRb- and CBP-independent pathway. (9512550)
1998
44
Renin plasma profile and sodium sensitivity of blood pressure in hypertensive patients with or without a family history of hypertension]. (9091855)
1996
45
Oxidative stress and mitochondrial dysfunction in neurodegeneration. (8858182)
1996
46
Insensitivity to anti-Muellerian hormone due to a mutation in the human anti-Muellerian hormone receptor. (7493017)
1995
47
Cerebral Cavernous Malformation, Familial (20301470)
1993
48
Familial essential tremor and idiopathic torsion dystonia are different genetic entities. (8232931)
1993
49
Spontaneous external carotid artery occlusion. (2760532)
1989
50
Acute gastric dilatation. (14939003)
1952

Variations for Paratyphoid Fever

About this section

Expression for genes affiliated with Paratyphoid Fever

About this section
Search GEO for disease gene expression data for Paratyphoid Fever.

Pathways for genes affiliated with Paratyphoid Fever

About this section

Pathways related to Paratyphoid Fever according to GeneCards Suite gene sharing:

(show all 41)
idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.6IFNGR1, TNFRSF1A
29.5IL1A, IL1R1
39.3IFNGR1, IL1B
4
Show member pathways
9.2IL1B, IL1R1
59.2CASP1, IL1B
69.2CASP1, IL1B
79.1IL1A, IL1B
89.1IL1A, IL1B
99.1IL1A, IL1B
109.1IL1A, IL1B
11
Show member pathways
9.1CASP1, IL1R1, TNFRSF1A
129.0IL1A, IL1R1, TNFRSF1A
13
Show member pathways
9.0CASP1, IL1A, TNFRSF1A
14
Show member pathways
8.9IFNGR1, IL1B, IL1R1
15
Show member pathways
8.8CASP1, IFNGR1, IL1B
168.7IL1B, IL1R1, TNFRSF1A
17
Show member pathways
8.7IL1A, IL1B, IL1R1
18
Show member pathways
8.7IL1A, IL1B, IL1R1
198.7IL1A, IL1B, IL1R1
208.7IL1A, IL1B, IL1R1
218.7CASP1, IL1A, IL1B
228.7CASP1, IL1A, IL1B
23
Show member pathways
8.6IL1A, IL1B, TNFRSF1A
24
Show member pathways
8.3IFNGR1, IL1A, IL1B, IL1R1
25
Show member pathways
8.3IFNGR1, IL1A, IL1B, IL1R1
26
Show member pathways
8.3CASP1, IL1A, IL1B, IL1R1
27
Show member pathways
8.3CASP1, IL1A, IL1B, IL1R1
28
Show member pathways
8.2IFNGR1, IL1A, IL1B, TNFRSF1A
298.2IFNGR1, IL1A, IL1B, TNFRSF1A
30
Show member pathways
8.2IFNGR1, IL1A, IL1B, TNFRSF1A
31
Show member pathways
8.2IL1A, IL1B, IL1R1, TNFRSF1A
32
Show member pathways
7.8IFNGR1, IL1A, IL1B, IL1R1, TNFRSF1A
337.8IFNGR1, IL1A, IL1B, IL1R1, TNFRSF1A
34
Show member pathways
7.8IFNGR1, IL1A, IL1B, IL1R1, TNFRSF1A
35
Show member pathways
7.8IFNGR1, IL1A, IL1B, IL1R1, TNFRSF1A
36
Show member pathways
7.8CASP1, IFNGR1, IL1A, IL1B, TNFRSF1A
37
Show member pathways
7.7CASP1, IL1A, IL1B, IL1R1, TNFRSF1A
387.7CASP1, IL1A, IL1B, IL1R1, TNFRSF1A
39
Show member pathways
7.7CASP1, IL1A, IL1B, IL1R1, TNFRSF1A
40
Show member pathways
7.4CASP1, IFNGR1, IL1A, IL1B, IL1R1, TNFRSF1A
41
Show member pathways
6.7CASP1, IFNGR1, IL1A, IL1B, IL1R1, PARK2

GO Terms for genes affiliated with Paratyphoid Fever

About this section

Biological processes related to Paratyphoid Fever according to GeneCards Suite gene sharing:

(show all 17)
idNameGO IDScoreTop Affiliating Genes
1interleukin-1 beta productionGO:00326119.8CASP1, IL1B
2response to ATPGO:00331989.8CASP1, IL1B
3fever generationGO:00016609.8IL1A, IL1B
4regulation of establishment of endothelial barrierGO:19031409.8IL1B, TNFRSF1A
5ovulationGO:00307289.7IL1B, IL1R1
6extrinsic apoptotic signaling pathway in absence of ligandGO:00971929.7IL1A, IL1B
7positive regulation of interleukin-2 biosynthetic processGO:00450869.7IL1A, IL1B
8negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:20012409.7IL1A, IL1B
9positive regulation of mitotic nuclear divisionGO:00458409.6IL1A, IL1B
10positive regulation of vascular endothelial growth factor productionGO:00105759.6IL1A, IL1B
11cellular response to glucose stimulusGO:00713339.5IL1B, IL1R1
12positive regulation of JNK cascadeGO:00463309.5IL1A, IL1B
13positive regulation of I-kappaB kinase/NF-kappaB signalingGO:00431239.2CASP1, IL1A, PARK2
14cellular response to mechanical stimulusGO:00712608.9CASP1, IL1B, TNFRSF1A
15cytokine-mediated signaling pathwayGO:00192218.6IL1A, IL1B, IL1R1, TNFRSF1A
16inflammatory responseGO:00069548.5IL1A, IL1B, TNFRSF1A
17signal transductionGO:00071658.5CASP1, IL1R1, PARK2, TNFRSF1A

Sources for Paratyphoid Fever

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet