MCID: PRT002
MIFTS: 52

Paratyphoid Fever malady

Categories: Infectious diseases, Rare diseases, Gastrointestinal diseases

Aliases & Classifications for Paratyphoid Fever

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Sources:
11Disease Ontology, 13DISEASES, 29ICD10, 30ICD10 via Orphanet, 31ICD9CM, 38MeSH, 44NCIt, 53Orphanet, 61SNOMED-CT, 67UMLS
See all MalaCards sources

Aliases & Descriptions for Paratyphoid Fever:

Name: Paratyphoid Fever 11 53 38 13 67
Paratyphoid B Fever 11 67
Paratyphoid C Fever 11 67
Paratyphoid Fever B 11
Paratyphoid a Fever 11
Paratyphoid Fever C 11
 
Paratyphoid Fever a 11
Paratyphoid a 11
Paratyphoid B 11
Paratyphoid C 11
Paratyphoid 11

Characteristics:

Orphanet epidemiological data:

53
paratyphoid fever:
Inheritance: Not applicable

Classifications:



Summaries for Paratyphoid Fever

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Disease Ontology:11 A primary bacterial infectious disease that results in infection located in intestine, has material basis in Salmonella enterica subsp enterica serovar Paratyphi A, B or C, which are transmitted by ingestion of contaminated food. The infection has symptom fever, has symptom headache, has symptom abdominal pain, has symptom malaise, has symptom anorexia, has symptom constipation, has symptom rosy spots on the central body, has symptom non productive cough (in early stage of illness), has symptom bradycardia, and has symptom hepatosplenomegaly.

MalaCards based summary: Paratyphoid Fever, also known as paratyphoid b fever, is related to typhoid fever and primary biliary cirrhosis, and has symptoms including fever, headache and abdominal pain. An important gene associated with Paratyphoid Fever is IFNGR1 (Interferon Gamma Receptor 1), and among its related pathways are Jak/STAT Signaling Pathway and Cellular Transformation by HTLV1. Affiliated tissues include intestine, skin and prostate, and related mouse phenotypes are renal/urinary system and skeleton.

Wikipedia:70 Paratyphoid fever, also known simply as paratyphoid, is a bacterial infection caused by one of the three... more...

Related Diseases for Paratyphoid Fever

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Diseases related to Paratyphoid Fever via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 43)
idRelated DiseaseScoreTop Affiliating Genes
1typhoid fever11.5
2primary biliary cirrhosis10.0IL1R1, TNFRSF1A
3immunodeficiency 27b, mycobacteriosis, ad9.9IFNGR1, IL1B
4dysentery9.9
5warm antibody hemolytic anemia9.9IL1B, IL1R1
6askin's tumor9.9IFNGR1, IL1B
7keloids9.9IL1B, IL1R1
8dystonia 17, torsion, autosomal recessive9.8CASP1, IL1B
9lymphocele9.8CASP1, IL1B
10syphilitic encephalitis9.8IL12B, IL1B
11hepatitis9.8
12hepatitis b9.8
13ileitis9.8
14hepatitis a9.8
15biliary atresia9.8
16purpura9.8
17appendicitis9.8
18duodenitis9.8
19vasculitis9.8
20keratosis9.7IFNGR1, IL1B
21bacteremia9.7
22aortic aneurysm9.7
23aneurysm9.7
24kidney rhabdoid cancer9.7IL1B, TNFRSF1A
25nasopharyngitis9.7CASP1, IL1B
26pediatric supratentorial ependymoma9.7IL12B, IL1B
27pulmonary systemic sclerosis9.6IL1B, IL1R1
28nephrosclerosis9.6IL1B, TNFRSF1A
29benign peritoneal mesothelioma9.6IL1B, TNFRSF1A
30cutaneous porphyria9.5CASP1, IFNGR1, IL1B
31pleomorphic lipoma9.5CASP1, IFNGR1, IL1B
32lethal midline granuloma9.5IFNGR1, IL12B, IL1B
33familial dupuytren contracture9.5CASP1, IL1B, IL1R1
34ovary transitional cell carcinoma9.5IFNGR1, IL12B, IL1B
35myelitis9.5IL1B, TNFRSF1A
36uterine inversion9.4IL1B, TNFRSF1A
37pyloric stenosis, infantile hypertrophic, 29.3CASP1, IL1B, TNFRSF1A
38low compliance bladder9.3IL12B, IL1B
39familial cold-induced inflammatory syndrome 19.0CASP1, IL1B, IL1R1, TNFRSF1A
40astrocytoma9.0CASP1, IFNGR1, IL1R1, PARK2, TNFRSF1A
41cinca syndrome9.0CASP1, IL1B, IL1R1, TNFRSF1A
42muckle-wells syndrome9.0CASP1, IL1B, IL1R1, TNFRSF1A
43malaria8.5CASP1, IFNGR1, IL12B, IL1B, TNFRSF1A

Graphical network of the top 20 diseases related to Paratyphoid Fever:



Diseases related to paratyphoid fever

Symptoms for Paratyphoid Fever

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Symptoms:

 11 (show all 10)
  • fever
  • headache
  • abdominal pain
  • malaise
  • anorexia
  • constipation
  • rosy spots on the central body
  • non productive cough (in early stage of illness)
  • bradycardia
  • hepatosplenomegaly

Drugs & Therapeutics for Paratyphoid Fever

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Drugs for Paratyphoid Fever (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1VaccinesPhase 4, Phase 1, Phase 26428
2Pharmaceutical SolutionsPhase 1, Phase 27793
3Liver ExtractsPhase 1, Phase 23868
4LecithinNutraceuticalPhase 1, Phase 270
5Soy BeanNutraceuticalPhase 1, Phase 2535

Interventional clinical trials:

(show all 11)
idNameStatusNCT IDPhase
1Introduction of the Vi Polysaccharide Typhoid Vaccine in Hue City, Central VietnamCompletedNCT00131820Phase 4
2Typhoid Vi Vaccine Effectiveness in Hechi, Guangxi, ChinaCompletedNCT00131833Phase 4
3Combined Vi Vaccination and Health Education Program on the Burden of Typhoid in ChildhoodCompletedNCT00125047Phase 4
4Evaluation of the Vi Polysaccharide Vaccine Against Typhoid FeverCompletedNCT00125008Phase 4
5TY800 Dose Escalation (Typhoid)CompletedNCT00269295Phase 1, Phase 2
6Safety and Efficacy Study of Mix Vaccine in Prostate Carcinoma PatientCompletedNCT02338700Phase 1, Phase 2
7Safety and Efficacy Study of Mix Vaccine in Breast Carcinoma PatientCompletedNCT02338804Phase 1, Phase 2
8Safety and Efficacy Study of Mix Vaccine in Hepatocyte Carcinoma PatientCompletedNCT02338778Phase 1, Phase 2
9Safety and Efficacy Study of Mix Vaccine in Pancreatic Carcinoma PatientCompletedNCT02338752Phase 1, Phase 2
10Investigating Enteric Fever - Salmonella Typhi and Paratyphi Challenge StudyRecruitingNCT02192008
11Understanding Paratyphoid InfectionActive, not recruitingNCT02100397

Search NIH Clinical Center for Paratyphoid Fever


Cochrane evidence based reviews: paratyphoid fever

Genetic Tests for Paratyphoid Fever

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Anatomical Context for Paratyphoid Fever

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MalaCards organs/tissues related to Paratyphoid Fever:

35
Skin, Prostate, Liver, Testes, Bone, Bone marrow

FMA organs/tissues related to Paratyphoid Fever:

17
Intestine

Animal Models for Paratyphoid Fever or affiliated genes

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MGI Mouse Phenotypes related to Paratyphoid Fever:

40 (show all 12)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.8CASP1, IFNGR1, IL1R1, TNFRSF1A
2MP:00053907.7IFNGR1, IL12B, IL1B, IL1R1, PARK2, TNFRSF1A
3MP:00107717.7CASP1, IFNGR1, IL1B, IL1R1, PARK2, TNFRSF1A
4MP:00020067.6CASP1, IFNGR1, IL12B, IL1B, IL1R1, TNFRSF1A
5MP:00053877.6CASP1, IFNGR1, IL12B, IL1B, IL1R1, TNFRSF1A
6MP:00053977.6CASP1, IFNGR1, IL12B, IL1B, IL1R1, TNFRSF1A
7MP:00036317.5CASP1, IFNGR1, IL1B, IL1R1, PARK2, TNFRSF1A
8MP:00053857.5CASP1, IFNGR1, IL1B, IL1R1, PARK2, TNFRSF1A
9MP:00107687.0CASP1, IFNGR1, IL12B, IL1B, IL1R1, PARK2
10MP:00053767.0CASP1, IFNGR1, IL12B, IL1B, IL1R1, PARK2

Publications for Paratyphoid Fever

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Articles related to Paratyphoid Fever:

(show top 50)    (show all 132)
idTitleAuthorsYear
1
Psychosis in paratyphoid fever - a case report from Australia. (24820292)
2014
2
Recurrent paratyphoid fever A co-infected with hepatitis A reactivated chronic hepatitis B. (24884719)
2014
3
Study of clinical profile and antibiotic sensitivity in paratyphoid Fever cases admitted at teaching hospital in South India. (24479019)
2012
4
Typhoid and paratyphoid fever - prevention in travellers. (21301658)
2010
5
Study on blood cultures and bacteria counts in the blood of paratyphoid fever A patients. (19526258)
2009
6
Fluoroquinolones for treating typhoid and paratyphoid fever (enteric fever). (18843659)
2008
7
Polymorphisms in proinflammatory genes and susceptibility to typhoid fever and paratyphoid fever. (17477815)
2007
8
PARK2/PACRG polymorphisms and susceptibility to typhoid and paratyphoid fever. (16734611)
2006
9
Paratyphoid fever in Vellore, South India. (16105360)
2005
10
Typhoid and paratyphoid fever in travellers. (16183516)
2005
11
Risk factors for typhoid and paratyphoid fever in Jakarta, Indonesia. (15173152)
2004
12
Typhoid and paratyphoid fever: a 10-year retrospective study of 41 cases in a Parisian hospital. (11726293)
2001
13
Oral administration of fluoroquinolones in the treatment of typhoid fever and paratyphoid fever in Japan. (11197787)
2000
14
Typhoid and paratyphoid fever in south-eastern Sydney, 1992-1997. (11022389)
2000
15
Paratyphoid fever due to Salmonella enterica serotype Paratyphi A. (9284393)
1997
16
A relapse of paratyphoid fever after treatment with ciprofloxacin in a child with congenital biliary atresia. (9183498)
1997
17
Monoclonal antibodies against protein antigens of salmonellae causing paratyphoid fever and their diagnostic application. (7488347)
1995
18
Paratyphoid fever presenting with renal failure and nephrotic syndrome. (2517555)
1989
19
Typhoid and paratyphoid fever. (115625)
1979
20
Influence of chloramphenicol and ampicillin on antibody response in typhoid-paratyphoid fever. (4984110)
1970
21
A comparative trial of furazolidone and chloramphenicol in typhoid and paratyphoid fever. (4995053)
1970
22
COMPARISON OF AMPICILLIN AND CHLORAMPHENICOL IN TREATMENT OF PARATYPHOID FEVER. (14072634)
1964
23
Paratyphoid Fever from Frozen Chinese Eggs. (20789773)
1963
24
Acute ileitis with ulceration and perforation due to paratyphoid fever; report of eighty-five cases. (13399825)
1957
25
Typhoid and paratyphoid fever; report of six cases with one death. (13361260)
1956
26
Second attack of paratyphoid fever. (13276681)
1956
27
PARATYPHOID fever and cream cakes. (13094092)
1953
28
The measurement of the duration of infection in paratyphoid fever. (13118154)
1953
29
Paratyphoid fever and bakers' confectionery; an analysis of an epidemic in South Wales, 1952. (13099191)
1953
30
Dissemination of paratyphoid fever from a bakery. (14824638)
1951
31
Chloromycetin in typhoid and paratyphoid fever. (14794145)
1950
32
Thrombocytopenic purpura complicating typhoid and paratyphoid fever. (18141777)
1949
33
A difficulty experienced in the bacteriological diagnosis of paratyphoid fever in cases treated with sulphonamides. (18130255)
1949
34
An outbreak of paratyphoid fever in Edmonton, Alta. (18894973)
1948
35
Field investigation of paratyphoid fever with typing of Salm. paratyphi B by means of Vi bacteriophage. (20262099)
1947
36
Paratyphoid fever. (20296482)
1946
37
3 cases of skeletal changes round the knee joint in paratyphoid fever in infants. (20985426)
1946
38
Paratyphoid Fever in Massachusetts. (18015087)
1939
39
TWO CASES OF HAEMORRHAGIC PARATYPHOID FEVER. (20776232)
1931
40
Paratyphoid Fever and Aertrycke Enteritis in Aberdeen-a Contrast. (20474903)
1926
41
Discussion on Paratyphoid Fever. (19979288)
1916
42
DISCUSSION ON PARATYPHOID FEVER. (19979278)
1916
43
Discussion on Paratyphoid Fever. (19979286)
1916
44
Discussion on Paratyphoid Fever. (19979289)
1916
45
DISCUSSION ON PARATYPHOID FEVER. (19979279)
1916
46
DISCUSSION ON PARATYPHOID FEVER. (19979292)
1916
47
COMBINED PREVENTIVE INOCULATION AGAINST TYPHOID AND PARATYPHOID FEVER AND BACILLARY DYSENTERY. (20767977)
1916
48
Discussion on Paratyphoid Fever. (19979285)
1916
49
Preliminary Note ON THE CLINICAL ASPECTS AND DIAGNOSIS OF PARATYPHOID FEVER. (20767886)
1915
50
Report of an Epidemic of Probable Paratyphoid Fever. (19599427)
1910

Variations for Paratyphoid Fever

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Expression for genes affiliated with Paratyphoid Fever

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Search GEO for disease gene expression data for Paratyphoid Fever.

Pathways for genes affiliated with Paratyphoid Fever

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Pathways related to Paratyphoid Fever according to GeneCards Suite gene sharing:

(show all 39)
idSuper pathwaysScoreTop Affiliating Genes
19.6IFNGR1, IL12B
2
Show member pathways
9.5IFNGR1, TNFRSF1A
39.4IL1R1, TNFRSF1A
49.3IFNGR1, IL1B
5
Show member pathways
9.2IL1B, IL1R1
69.2IL1B, IL1R1
79.1CASP1, IL1B
89.1CASP1, IL1B
99.1IL12B, IL1B
109.1IL12B, IL1B
119.1IL12B, IL1B
12
Show member pathways
9.0IFNGR1, IL12B, TNFRSF1A
13
Show member pathways
8.9CASP1, IL1R1, TNFRSF1A
14
Show member pathways
8.9IFNGR1, IL1B, IL1R1
15
Show member pathways
8.9IFNGR1, IL1B, IL1R1
16
Show member pathways
8.8CASP1, IFNGR1, IL1B
17
Show member pathways
8.8IFNGR1, IL12B, IL1B
18
Show member pathways
8.7CASP1, IL1B, IL1R1
19
Show member pathways
8.7IL12B, IL1B, IL1R1
208.7IL12B, IL1B, IL1R1
21
Show member pathways
8.7IL12B, IL1B, IL1R1
228.6IL1B, IL1R1, TNFRSF1A
23
Show member pathways
8.6IL1B, IL1R1, TNFRSF1A
248.6CASP1, IL12B, IL1B
258.6CASP1, IL12B, IL1B
26
Show member pathways
8.2IFNGR1, IL1B, IL1R1, TNFRSF1A
278.2IFNGR1, IL1B, IL1R1, TNFRSF1A
28
Show member pathways
8.2IFNGR1, IL1B, IL1R1, TNFRSF1A
29
Show member pathways
8.1IFNGR1, IL12B, IL1B, TNFRSF1A
30
Show member pathways
8.1IFNGR1, IL12B, IL1B, TNFRSF1A
318.1IFNGR1, IL12B, IL1B, TNFRSF1A
328.1CASP1, IL1B, IL1R1, TNFRSF1A
33
Show member pathways
7.7IFNGR1, IL12B, IL1B, IL1R1, TNFRSF1A
34
Show member pathways
7.6CASP1, IFNGR1, IL12B, IL1B, TNFRSF1A
35
Show member pathways
7.6CASP1, IL12B, IL1B, IL1R1, TNFRSF1A
36
Show member pathways
7.6CASP1, IL12B, IL1B, IL1R1, TNFRSF1A
37
Show member pathways
7.2CASP1, IFNGR1, IL12B, IL1B, IL1R1, TNFRSF1A
38
Show member pathways
7.2CASP1, IFNGR1, IL12B, IL1B, IL1R1, TNFRSF1A
39
Show member pathways
6.7CASP1, IFNGR1, IL12B, IL1B, IL1R1, PARK2

GO Terms for genes affiliated with Paratyphoid Fever

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Biological processes related to Paratyphoid Fever according to GeneCards Suite gene sharing:

(show all 18)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of inflammatory responseGO:00507299.8IL12B, TNFRSF1A
2ovulationGO:00307289.8IL1B, IL1R1
3interleukin-1 beta productionGO:00326119.7CASP1, IL1B
4positive regulation of NF-kappaB import into nucleusGO:00423469.7IL12B, IL1B
5positive regulation of interferon-gamma productionGO:00327299.7IL12B, IL1B
6regulation of establishment of endothelial barrierGO:19031409.7IL1B, TNFRSF1A
7cellular response to glucose stimulusGO:00713339.6IL1B, IL1R1
8cellular response to organic substanceGO:00713109.5CASP1, IL1B
9regulation of autophagyGO:00105069.4CASP1, PARK2
10positive regulation of granulocyte macrophage colony-stimulating factor productionGO:00327259.4IL12B, IL1B
11positive regulation of T cell proliferationGO:00421029.3IL12B, IL1B
12regulation of inflammatory responseGO:00507279.2CASP1, IL1R1
13response to ATPGO:00331989.1CASP1, IL1B
14cell surface receptor signaling pathwayGO:00071669.0IL12B, IL1R1, TNFRSF1A
15cellular response to mechanical stimulusGO:00712608.9CASP1, IL1B, TNFRSF1A
16response to lipopolysaccharideGO:00324968.7CASP1, IL1B, TNFRSF1A
17cytokine-mediated signaling pathwayGO:00192218.4IL12B, IL1B, IL1R1, TNFRSF1A
18positive regulation of I-kappaB kinase/NF-kappaB signalingGO:00431238.4CASP1, IL1B, PARK2, TNFRSF1A

Sources for Paratyphoid Fever

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet