MCID: PRK045
MIFTS: 19

Parkinson Disease 5 malady

Summaries for Parkinson Disease 5

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46OMIM, 32MalaCards
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MalaCards: Parkinson Disease 5 is related to pick's disease and motor neuron disease. An important gene associated with Parkinson Disease 5 is UCHL1 (ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)), and among its related pathways is Neuroscience. The compounds vitamin b12 and choline have been mentioned in the context of this disorder. Related mouse phenotypes are hematopoietic system and renal/urinary system.

Description from OMIM:46 613643

Aliases & Classifications for Parkinson Disease 5

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46OMIM
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Aliases & Descriptions:

parkinson disease 5 46


Related Diseases for Parkinson Disease 5

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of diseases related to Parkinson Disease 5:



Diseases related to parkinson disease 5

Clinical Features for Parkinson Disease 5

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46OMIM
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Clinical features from OMIM:

613643

Drugs & Therapeutics for Parkinson Disease 5

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Parkinson Disease 5

Search CenterWatch for Parkinson Disease 5

Genetic Tests for Parkinson Disease 5

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Anatomical Context for Parkinson Disease 5

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Animal Models for Parkinson Disease 5 or affiliated genes

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Sources:
36MGI
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MGI Mouse Phenotypes related to Parkinson Disease 5:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053978.5MAPT, UCHL1, COMT
2MP:00053678.2MAPT, UCHL1, COMT

Publications for Parkinson Disease 5

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Genetic Variations for Parkinson Disease 5

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Sources:
62UniProtKB/Swiss-Prot
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Genetic disease variations for Parkinson Disease 5:

62
id Symbol AA change Variation ID SNP ID
1UCHL1p.Ile93MetVAR_015678

Expression for genes affiliated with Parkinson Disease 5

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Parkinson Disease 5

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Pathways for genes affiliated with Parkinson Disease 5

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Sources:
4Cell Signaling Technology
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Pathways related to Parkinson Disease 5 according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3MAPT, UCHL1

Compounds for genes affiliated with Parkinson Disease 5

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Sources:
44Novoseek, 11DrugBank, 24HMDB, 49PharmGKB, 28IUPHAR
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Compounds related to Parkinson Disease 5 according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1vitamin b12449.3MAPT, COMT
2choline44 11 2411.3MAPT, COMT
3isoproterenol44 1110.2COMT, MAPT
4folate449.2COMT, MAPT
5nicotine44 49 28 1112.1COMT, MAPT
6nmda44 2810.1MAPT, COMT
7valine449.0MAPT, COMT
8methionine448.8MAPT, COMT
9dopamine44 28 11 2411.7MAPT, UCHL1, COMT
10cysteine448.7COMT, MAPT, UCHL1

GO Terms for genes affiliated with Parkinson Disease 5

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Sources:
16Gene Ontology
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Cellular components related to Parkinson Disease 5 according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1axonGO:0304249.3MAPT, UCHL1

Biological processes related to Parkinson Disease 5 according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1adult walking behaviorGO:0076289.3MAPT, UCHL1

Products for genes affiliated with Parkinson Disease 5

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Parkinson Disease 5

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet