Parkinson Disease 6, Early Onset: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical Trials

Summaries for Parkinson Disease 6, Early Onset

Sources:
⁴⁶OMIM, ³²MalaCards
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MalaCards: Parkinson Disease 6, Early Onset An important gene associated with Parkinson Disease 6, Early Onset is PINK1 (PTEN induced putative kinase 1).

Description from OMIM:⁴⁶ 605909

Aliases & Classifications for Parkinson Disease 6, Early Onset

Sources:
⁴⁶OMIM
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Ear diseases

Aliases & Descriptions:

parkinson disease 6, early onset ⁴⁶

Related Diseases for Parkinson Disease 6, Early Onset

Diseases in the Parkinson's Disease family:

Lrrk2-Related Parkinson Disease	Parkinson Disease Type 3
Parkinson Disease Type 9	Park7-Related Parkinson Disease
Snca-Related Parkinson Disease	Htra2-Related Parkinson Disease
Vps35-Related Parkinson Disease	Fbxo7-Related Parkinson Disease
parkinson disease 6, early onset	Parkinson Disease 19, Juvenile-Onset
Parkinson Disease 10	Parkinson Disease, Late-Onset
Parkinson Disease 16	Parkinson Disease 13
Parkinson Disease 11	Parkinson Disease 18
Parkinson Disease 5	Parkinson Disease 4
Parkinson Disease 1	Parkinson Disease, Juvenile, Type 2
Parkinson Disease 8	Parkinson Disease 17
Parkinson Disease 20, Early-Onset	Parkinson Disease 14
Parkinson Disease 12

Clinical Features for Parkinson Disease 6, Early Onset

Sources:
⁴⁶OMIM
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Clinical features from OMIM:

605909

Clinical synopsis from OMIM:

605909

Drugs & Therapeutics for Parkinson Disease 6, Early Onset

Sources:
⁵CenterWatch, ⁴¹NIH Clinical Center, ⁶ClinicalTrials
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Approved drugs:

Search CenterWatch for Parkinson Disease 6, Early Onset

Drug clinical trials:

Search ClinicalTrials for Parkinson Disease 6, Early Onset

Search NIH Clinical Center for Parkinson Disease 6, Early Onset

Search CenterWatch for Parkinson Disease 6, Early Onset

Genetic Tests for Parkinson Disease 6, Early Onset

Anatomical Context for Parkinson Disease 6, Early Onset

Animal Models for Parkinson Disease 6, Early Onset or affiliated genes

Publications for Parkinson Disease 6, Early Onset

Genes related to Parkinson Disease 6, Early Onset

Sources:
¹⁷GeneCards, ⁴⁵Novus Biologicals, ³¹LifeSpan BioSciences, Inc., ⁴⁶OMIM, ⁶²UniProtKB/Swiss-Prot
See all sources

Genes related to Parkinson Disease 6, Early Onset:

id	Symbol	Products	Description	Score	Implication
1	PINK1		PTEN induced putative kinase 1	31.28	Molecular basis known ⁴⁶ Causative variation ⁶² GeneCards inferred : Disorders (show sections)

Products for genes related to Parkinson Disease 6, Early Onset disease:

id	Company	Proteins	Lysates	Antibodies
1	Novus Biologicals	1	1	1
2	LSBio	-	-	1

Genetic Variations for Parkinson Disease 6, Early Onset

Sources:
⁶²UniProtKB/Swiss-Prot
See all sources

Genetic disease variations for Parkinson Disease 6, Early Onset:

⁶² (show all 23)

id	Symbol	AA change	Variation ID
1	PINK1	p.Gly309Asp	VAR_018994
2	PINK1	p.Cys92Phe	VAR_046568
3	PINK1	p.Ala168Pro	VAR_046575
4	PINK1	p.Pro196Leu	VAR_046577
5	PINK1	p.Ala217Asp	VAR_046578
6	PINK1	p.Glu240Lys	VAR_046581
7	PINK1	p.Leu268Val	VAR_046584
8	PINK1	p.His271Gln	VAR_046585
9	PINK1	p.Arg279His	VAR_046587
10	PINK1	p.Thr313Met	VAR_046589
11	PINK1	p.Leu347Pro	VAR_046593
12	PINK1	p.Cys388Arg	VAR_046596
13	PINK1	p.Glu417Gly	VAR_046599
14	PINK1	p.Arg464His	VAR_046605
15	PINK1	p.Leu489Pro	VAR_046607
16	PINK1	p.Cys125Gly	VAR_062773
17	PINK1	p.Ala280Thr	VAR_062774
18	PINK1	p.Leu369Pro	VAR_062775
19	PINK1	p.Gly386Ala	VAR_062776
20	PINK1	p.Pro399Leu	VAR_062777
21	PINK1	p.Arg407Gln	VAR_062778
22	PINK1	p.Gly409Val	VAR_062779
23	PINK1	p.Gln126Pro	VAR_064344