Parkinson Disease 7, Autosomal Recessive Early-onset malady

MalaCards: Parkinson Disease 7, Autosomal Recessive Early-onset, also known as parkinson disease, is related to parkinson's disease and dementia. An important gene associated with Parkinson Disease 7, Autosomal Recessive Early-onset is PARK7 (parkinson protein 7). The drugs bromocriptine and pergolide have been mentioned in the context of this disorder.

OMIM: 606324

parkinson disease 7, autosomal recessive early-onset 33 parkinson disease 43

Diseases related to parkinson disease 7, autosomal recessive early-onset by text searches and GeneDecks gene sharing:

(show top 50)    (show all 59)

id	Related Disease	Score	Top Affiliating Genes
1	parkinson's disease	13.2
2	dementia	8.9
3	alzheimer's disease	8.4
4	lrrk2-related parkinson disease	8.2
5	park7-related parkinson disease	8.0
6	autosomal recessive juvenile parkinson disease	8.0
7	htra2-related parkinson disease	7.7
8	pink1 type of young-onset parkinson disease	7.7
9	parkinson disease type 3	7.7
10	essential tremor	7.5
11	neurodegeneration	7.5
12	neuronitis	7.5
13	parkin type of juvenile parkinson disease	7.5
14	snca-related parkinson disease	7.5
15	parkinson disease type 9	7.2
16	parkinson disease 10	7.2
17	tremor	7.2
18	parkinson disease multi-gene panels	6.8
19	parkinson disease 6, early onset	6.8
20	parkinson disease 12	6.8
21	parkinson disease-16	6.8
22	parkinson disease, juvenile, type 2	6.8
23	parkinson disease 11	6.8
24	parkinson disease 15, autosomal recessive	6.8
25	parkinson disease 14	6.8
26	parkinson disease 4	6.8
27	parkinson disease 1	6.8
28	parkinson disease, resistance to	6.8
29	postencephalitic parkinson disease	6.8
30	secondary parkinson disease	6.8
31	frontotemporal dementia	6.3
32	gaucher's disease	6.3
33	homocysteine	6.3
34	lateral sclerosis	6.3
35	lewy body dementia	6.3
36	parkinson disease 5	6.3
37	paralysis agitans, juvenile, of hunt	6.3
38	pathological gambling	6.3
39	vps35-related parkinson disease	6.3
40	cholesterol	6.3
41	fbxo7-related parkinson disease	6.3
42	multiple sclerosis	5.4
43	oculopharyngeal muscular dystrophy	5.4
44	pallidopyramidal syndrome	5.4
45	prolidase deficiency	5.4
46	retinitis	5.4
47	schizophrenia	5.4
48	tauopathy	5.4
49	alcoholism	5.4
50	torsion dystonia	5.4

Clinical features from OMIM: 606324

Approved drugs:

Drug clinical trials:

Inferred drug relations via UMLS/NDF-RT:

^43 28 amantadine, amantadine hydrochloride, benztropine, benztropine mesylate, biperiden, biperiden hydrochloride, biperiden lactate, bromocriptine, bromocriptine mesylate, cabergoline, carbidopa, entacapone, levodopa, pergolide, pergolide mesylate, pramipexole, pramipexole dihydrochloride, ropinirole, ropinirole hydrochloride, selegiline, selegiline hydrochloride, tolcapone, trihexyphenidyl, trihexyphenidyl hydrochloride

Genes related to parkinson disease 7, autosomal recessive early-onset according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	PARK7	parkinson protein 7	11.1	Disorders