Summaries for Parotitis

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Wikipedia:65 Parotitis is an inflammation of one or both parotid glands, the major salivary glands located on either... more...

MalaCards based summary: Parotitis is related to pancreatitis and meningitis. An important gene associated with Parotitis is SPINK1 (serine peptidase inhibitor, Kazal type 1), and among its related pathways are Pentose Phosphate Pathway and amb2 Integrin signaling. The compounds neotetrazolium and 6-Phosphonoglucono-D-lactone have been mentioned in the context of this disorder. Affiliated tissues include salivary gland, thyroid and eye, and related mouse phenotypes are immune system and hematopoietic system.

Disease Ontology:10 A parotid disease characterized by the inflammation of one or both parotid glands.

Aliases & Classifications for Parotitis

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Sources:
10Disease Ontology, 12DISEASES, 45Novoseek, 62UMLS, 35MeSH, 57SNOMED-CT
See all sources

Parotitis, Aliases & Descriptions:

Name: Parotitis 10 12 45 62


External Ids:

Disease Ontology10 DOID:10301
MeSH35 D010309

Related Diseases for Parotitis

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Graphical network of the top 20 diseases related to Parotitis:



Diseases related to parotitis

Symptoms for Parotitis

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Drugs & Therapeutics for Parotitis

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Drug clinical trials:

Search ClinicalTrials for Parotitis

Search NIH Clinical Center for Parotitis

Genetic Tests for Parotitis

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Anatomical Context for Parotitis

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MalaCards organs/tissues related to Parotitis:

33
Salivary gland, Thyroid, Eye, Bone, Lymph node, Brain, Lung, Breast, Myeloid

Animal Models for Parotitis or affiliated genes

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MGI Mouse Phenotypes related to Parotitis:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053877.3LTF, CD79A, CRP, MMP2, MMP9, SPINK1
2MP:00053977.0SPINK1, G6PD, MMP9, MMP2, CD79A, LTF
3MP:00053766.3LTF, SPINK1, G6PD, MMP9, MMP2, H6PD

Publications for Parotitis

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Articles related to Parotitis:

(show top 50)    (show all 521)
idTitleAuthorsYear
1
Juvenile recurrent parotitis in children: diagnosis and treatment using sialography. (25001449)
2014
2
Incessant cry--rare presentation of neonatal parotitis. (25252534)
2014
3
Acute transient parotitis in a child with primitive neuroectodermal tumor after a standard dose etoposide. (25006307)
2014
4
Transient parotitis after upper gastrointestinal endoscopy. (24338172)
2013
5
Sialendoscopy in juvenile recurrent parotitis: a review of the literature. (24376291)
2013
6
Acute neonatal parotitis caused by streptococcus pyogenes: a case report. (20164068)
2010
7
Transient parotitis after conscious sedation for endoscopy. (19319777)
2009
8
Community-acquired methicillin-resistant Staphylococcus aureus: an emerging cause of acute bacterial parotitis. (19139712)
2009
9
A life-threatening complication of acute parotitis. (17822812)
2008
10
Differentiating acute suppurative parotitis from acute exacerbation of a chronic parotitis: case reports. (18718411)
2008
11
Association between the occurrence of matrix metalloproteinases 2 and 9 in parotid saliva with the degree of parotid gland damage in juvenile recurrent parotitis. (18567510)
2008
12
Juvenile recurrent parotitis: clinical, sialographic and ultrasonographic features. (17263859)
2007
13
Bilateral suppurative parotitis in a newborn. (16624200)
2006
14
Recurrent parotitis in a seven year-old boy. (16208064)
2005
15
Parotitis due to ritodrine tocolytic treatment for preterm labor. (15806068)
2005
16
Extra-cranial metastasis of glioblastoma multiforme presenting as acute parotitis. (16455543)
2005
17
Asparaginase-induced acute parotitis: an uncommon and self-limiting complication. (12116090)
2002
18
Tuberculous parotitis. (12379196)
2002
19
Recurrent HIV parotitis. (11418740)
2001
20
Tympanic neurectomy and chronic parotitis. (11200598)
2000
21
Prophylactic antibiotics in recurrent parotitis in a patient with Sjogren's syndrome. (10357124)
1999
22
Sonographic analysis of recurrent parotitis in children: a comparative study with sialographic findings. (9830657)
1998
23
The possible significance of cytomegaloviral parotitis in infant and early childhood deaths. (9431318)
1997
24
Chronic suppurative parotitis: a proposed classification. (9206105)
1996
25
Recurrent parotitis. (8503688)
1993
26
Neonatal suppurative parotitis: a vanishing disease? (8131800)
1993
27
Recurrent parotitis in childhood. (8432079)
1993
28
Recurrent parotitis in childhood. (1563203)
1992
29
Parotitis in a three-year-old. (1878333)
1991
30
The surgical management of chronic parotitis. (2243516)
1990
31
Nosocomial gram-negative parotitis. (3079657)
1986
32
Computed tomography and sialography of chronic pyogenic parotitis. (6509287)
1984
33
Infectious parotitis in SjAPgren's syndrome: a case report and review of the literature. (313447)
1979
34
Mumps pancreatitis without parotitis. (4692679)
1973
35
Parotitis, parotid abscess and facial palsy. (5058482)
1972
36
Primary suppurative parotitis. (5124870)
1971
37
Recurrent parotitis in children. (5357583)
1969
38
A case of suppurative parotitis. (5909099)
1966
39
PAROTITIS AND FACIAL PARALYSIS IN MID-LINE GRANULOMA. (14256342)
1965
40
POSTOPERATIVE PAROTITIS-PARAPAROTID SPACE INFECTION. REPORT OF A CASE. (14063805)
1964
41
Parotitis in weanling mice produced by Coxsackie B-1 (Conn.-5) virus. (14001101)
1962
42
Suppurative parotitis. (13689544)
1961
43
Postoperative parotitis: a complication in a fracture of the maxilla. (13780077)
1961
44
Chronic parotitis; with illustrative case report. (13553307)
1958
45
Chronic sialectatic parotitis in the light of pathological studies on parotidectomy material. (13260589)
1955
46
Recurrent parotitis in children. (13058436)
1953
47
Herpes zoster with a varicelliform eruption and parotitis in chronic leukemia. (14794487)
1951
48
Suppurative parotitis. (14777386)
1950
49
Mumps meningoencephalitis with and without parotitis. (18147966)
1949
50
Laryngeal edema in epidemic parotitis. (18913528)
1948

Variations for Parotitis

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Expression for genes affiliated with Parotitis

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Search GEO for disease gene expression data for Parotitis.

Pathways for genes affiliated with Parotitis

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Pathways related to Parotitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
pentose phosphate pathway (non-oxidative branch)38
pentose phosphate pathway38
PRPP biosynthesis38
9.6H6PD, G6PD
29.0MMP2, MMP9
3
Show member pathways
9.0MMP2, MMP9
49.0MMP2, MMP9
59.0MMP9, MMP2
69.0MMP2, MMP9
79.0MMP2, MMP9
89.0MMP9, MMP2

Compounds for genes affiliated with Parotitis

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Compounds related to Parotitis according to GeneCards/GeneDecks:

(show top 50)    (show all 142)
idCompoundScoreTop Affiliating Genes
1neotetrazolium4510.0H6PD, G6PD
26-Phosphonoglucono-D-lactone2610.0G6PD, H6PD
3o-ethylhydroxylamine459.9G6PD, H6PD
4galactose-6-phosphate459.9CRP, G6PD
5no-dimethylhydroxylamine459.8G6PD, H6PD
6glutaraldehyde459.6G6PD, H6PD, CD79A
7sulfasalazine30 45 51 1312.5CRP, G6PD, CD79A
8lactulose459.4LTF, CRP, CD79A
9pmma459.4LTF, CRP, CD79A
10cgs-27023a459.3MMP2, MMP9
11flavanol459.3MMP2, MMP9
12methacholine45 51 1311.3LTF, CD79A, CRP
13col 3459.2MMP9, MMP2
14methyl selenol459.2MMP2, MMP9
15polyethylene glycol459.1H6PD, G6PD, CD79A, CRP
16malate459.1MMP9, G6PD, H6PD
17neopterin459.0LTF, CD79A, CRP
18malondialdehyde459.0H6PD, CRP, G6PD
19vitamin b12459.0CRP, CD79A, LTF, G6PD
20lactose45 139.9LTF, MMP9, G6PD
218-isoprostane458.9MMP9, MMP2, CRP
22aspirin45 51 30 2611.8CD79A, G6PD, MMP2, CRP
23erythromycin45 3 51 1311.8MMP9, LTF, MMP2
24succinate458.7H6PD, LTF, MMP9, G6PD
25cyclophosphamide45 51 1310.5MMP9, G6PD, CRP, LTF
26ivig458.5MMP2, CRP, CD79A, MMP9
27doxycycline45 139.5MMP9, MMP2, CD79A, LTF
28hyaluronic acid45 269.5CD79A, LTF, MMP2, MMP9
29epinephrine45 26 1310.5G6PD, CD79A, MMP2, MMP9
30ribavirin45 51 1310.5G6PD, MMP9, LTF, MMP2
31chloramphenicol45 3 51 1311.5LTF, CRP, MMP9, G6PD
32pioglitazone30 45 51 1311.5G6PD, MMP9, MMP2, CRP
33h2o2458.4G6PD, MMP2, H6PD, LTF, CD79A
34methotrexate51 45 1310.4MMP2, MMP9, CRP, CD79A
35azathioprine45 3 51 1311.4CRP, MMP2, G6PD, CD79A, LTF
36citrate458.4LTF, CRP, G6PD, MMP2, CD79A
37vitamin a45 26 1310.4MMP9, MMP2, CRP, LTF
38fibrinogen458.3MMP9, CD79A, LTF, CRP
39ascorbic acid45 269.0LTF, H6PD, G6PD, CD79A, CRP, MMP2
40norepinephrine45 26 1310.0CRP, LTF, MMP9, CD79A, MMP2
41aspartate457.9LTF, MMP9, MMP2, G6PD, CRP
42vegf457.8MMP2, LTF, CD79A, MMP9, CRP
43folate457.7CRP, H6PD, MMP2, MMP9, CD79A, G6PD
44lactate457.7G6PD, CRP, H6PD, MMP2, MMP9, CD79A
45estrogen457.7LTF, PGRMC1, CD79A, G6PD, MMP9, MMP2
46alanine457.6MMP2, CRP, CD79A, LTF, MMP9
47n acetylcysteine457.6LTF, G6PD, CRP, CD79A, MMP2, MMP9
48glutamate457.4LTF, CD79A, H6PD, MMP2, MMP9
49testosterone45 61 26 1310.4CD79A, CRP, H6PD, MMP9, PGRMC1, G6PD
50creatinine456.9LTF, G6PD, MMP9, MMP2, H6PD, CRP

GO Terms for genes affiliated with Parotitis

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Cellular components related to Parotitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056158.0LTF, CRP, MMP2, MMP9
2extracellular regionGO:00055767.4LTF, CRP, MMP2, MMP9, SPINK1

Biological processes related to Parotitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1pentose-phosphate shuntGO:00060989.3H6PD, G6PD
2embryo implantationGO:00075669.0MMP2, MMP9

Molecular functions related to Parotitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1glucose-6-phosphate dehydrogenase activityGO:00043459.5H6PD, G6PD
2NADP bindingGO:00506619.3H6PD, G6PD
3protein bindingGO:00055156.9G6PD, PGRMC1, MMP9, MMP2, CRP, LTF

Products for genes affiliated with Parotitis

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Sources for Parotitis

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4CDC
15ExPASy
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet