MCID: PRT001
MIFTS: 14

Partial Fetal Alcohol Syndrome malady

Category: Fetal diseases

Aliases & Classifications for Partial Fetal Alcohol Syndrome

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Aliases & Descriptions for Partial Fetal Alcohol Syndrome:

Name: Partial Fetal Alcohol Syndrome 10 12 65

Classifications:



External Ids:

Disease Ontology10 DOID:0050666
UMLS65 C3661483

Summaries for Partial Fetal Alcohol Syndrome

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Disease Ontology:10 A fetal alcohol spectrum disorder that results in most, but not all, of the growth deficiency and/or craniofacial features of fetal alcohol syndrome including central nervous system dysfunction due to prenatal alcohol exposure.

MalaCards based summary: Partial Fetal Alcohol Syndrome is related to fetal alcohol spectrum disorder and mental retardation, x-linked, syndromic 13. An important gene associated with Partial Fetal Alcohol Syndrome is PFAS (Phosphoribosylformylglycinamidine Synthase), and among its related pathways is Cell adhesion molecules (CAMs). Related mouse phenotypes are nervous system and mortality/aging.

Related Diseases for Partial Fetal Alcohol Syndrome

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Diseases related to Partial Fetal Alcohol Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1fetal alcohol spectrum disorder10.5
2mental retardation, x-linked, syndromic 1310.1NTNG1, NTNG2
3factor x deficiency10.0
4gastric cancer10.0
5cryptosporidiosis10.0
6alcohol-related neurodevelopmental disorder7.6ACER3, FEZF2, NEUROD2, NEUROG2, NOVA1, NOVA2

Graphical network of diseases related to Partial Fetal Alcohol Syndrome:



Diseases related to partial fetal alcohol syndrome

Symptoms for Partial Fetal Alcohol Syndrome

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Drugs & Therapeutics for Partial Fetal Alcohol Syndrome

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Drugs for Partial Fetal Alcohol Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Cholineapproved, nutraceuticalPhase 2, Phase 113062-49-7305
Synonyms:
(2-Hydroxyethyl)trimethyl ammonium
(2-Hydroxyethyl)trimethylammonium
(beta-hydroxyethyl)trimethylammonium
2-Hydroxy-N,N,N-trimethyl-ethanaminium
2-Hydroxy-N,N,N-trimethylethanaminium
Bilineurine
Biocolina
Biocoline
Choline
Choline cation
 
Choline ion
Cholinum
Hepacholine
Hormocline
Lipotril
N,N,N-Trimethylethanol-ammonium
N,N,N-Trimethylethanolammonium
N,N,N-trimethylethanol-ammonium
N-trimethylethanolamine
Neocolina
Paresan
trimethylethanolamine
2
GlycerolexperimentalPhase 219156-81-5753
Synonyms:
1,2,3-Trihydroxypropane
Bulbold
Cristal
E 422
Emery 916
Glyceol Opthalgan
Glycerin
Glycerine
Glyceritol
Glycerol
 
Glycyl alcohol
Glyrol
Glysanin
IFP
Incorporation factor
Mackstat H 66
Osmoglyn
Pricerine 9091
Propanetriol
RG-S
Trihydroxypropane
Tryhydroxypropane
3Hypolipidemic AgentsPhase 2, Phase 12228
4Nootropic AgentsPhase 2, Phase 1604
5Gastrointestinal AgentsPhase 2, Phase 16401
6Phase 2, Phase 1
7AntimetabolitesPhase 2, Phase 19454

Interventional clinical trials:

idNameStatusNCT IDPhase
1Choline Supplementation in Children With Fetal Alcohol Spectrum DisordersCompletedNCT01911299Phase 2
2Postnatal Choline Supplementation in Children With Prenatal Alcohol ExposureCompletedNCT01149538Phase 1, Phase 2
3Parenting Training for Children With FASDRecruitingNCT02210455

Search NIH Clinical Center for Partial Fetal Alcohol Syndrome

Genetic Tests for Partial Fetal Alcohol Syndrome

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Anatomical Context for Partial Fetal Alcohol Syndrome

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Animal Models for Partial Fetal Alcohol Syndrome or affiliated genes

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MGI Mouse Phenotypes related to Partial Fetal Alcohol Syndrome:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00036317.4FEZF2, NEUROD2, NEUROG2, NOVA1, NOVA2, NTNG1
2MP:00107686.9FEZF2, NEUROD2, NEUROG2, NOVA1, NOVA2, NTNG1

Publications for Partial Fetal Alcohol Syndrome

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Articles related to Partial Fetal Alcohol Syndrome:

idTitleAuthorsYear
1
Mycophenolate mofetil (MMF) in the treatment of epidermolysis bullosa acquisita (EBA) long-term follow-up. (27051767)
2015
2
Laparoscopic simple nephrectomy patient with situs inversus totalis and left renal hypoplasia: A case report. (26279730)
2015
3
Clubbing, cyanosis and a new diagnosis of atrial septal defect in a parturient: a straightforward diagnosis of Eisenmenger syndrome? (23329721)
2013

Variations for Partial Fetal Alcohol Syndrome

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Expression for genes affiliated with Partial Fetal Alcohol Syndrome

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Search GEO for disease gene expression data for Partial Fetal Alcohol Syndrome.

Pathways for genes affiliated with Partial Fetal Alcohol Syndrome

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Pathways related to Partial Fetal Alcohol Syndrome according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.7NTNG1, NTNG2

GO Terms for genes affiliated with Partial Fetal Alcohol Syndrome

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Sources for Partial Fetal Alcohol Syndrome

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet