MCID: PRT086
MIFTS: 27

Partial Hydatidiform Mole

Categories: Reproductive diseases, Rare diseases

Aliases & Classifications for Partial Hydatidiform Mole

MalaCards integrated aliases for Partial Hydatidiform Mole:

Name: Partial Hydatidiform Mole 56
Incomplete Hydatidiform Mole 56
Incomplete Molar Pregnancy 56
Hydatidiform Mole, Partial 69
Partial Molar Pregnancy 56

Characteristics:

Orphanet epidemiological data:

56
partial hydatidiform mole
Inheritance: Not applicable; Age of onset: Adult; Age of death: normal life expectancy;

Classifications:



External Ids:

Orphanet 56 ORPHA254693
UMLS via Orphanet 70 C0334529
ICD10 via Orphanet 34 O01.1

Summaries for Partial Hydatidiform Mole

MalaCards based summary : Partial Hydatidiform Mole, also known as incomplete hydatidiform mole, is related to hydatidiform mole, recurrent, 2 and hydatidiform mole, recurrent, 1. An important gene associated with Partial Hydatidiform Mole is NLRP7 (NLR Family Pyrin Domain Containing 7). The drugs Chorionic Gonadotropin and Levoleucovorin have been mentioned in the context of this disorder. Affiliated tissues include uterus, bone and placenta.

Wikipedia : 72 Molar pregnancy is an abnormal form of pregnancy in which a non-viable fertilized egg implants in the... more...

Related Diseases for Partial Hydatidiform Mole

Graphical network of the top 20 diseases related to Partial Hydatidiform Mole:



Diseases related to Partial Hydatidiform Mole

Symptoms & Phenotypes for Partial Hydatidiform Mole

Drugs & Therapeutics for Partial Hydatidiform Mole

Drugs for Partial Hydatidiform Mole (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 24)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Chorionic Gonadotropin Phase 4
2
Levoleucovorin Approved Phase 2, Phase 3 68538-85-2
3
Methotrexate Approved Phase 2, Phase 3 1959-05-2, 59-05-2 126941
4
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2, Phase 3 59-30-3 6037
5
leucovorin Approved, Nutraceutical Phase 2, Phase 3 58-05-9 143 6006
6 Micronutrients Phase 2, Phase 3
7 Trace Elements Phase 2, Phase 3
8 Vitamins Phase 2, Phase 3
9 Antidotes Phase 2, Phase 3
10 Antimetabolites Phase 2, Phase 3
11 Antimetabolites, Antineoplastic Phase 2, Phase 3
12 Antirheumatic Agents Phase 2, Phase 3
13 Dermatologic Agents Phase 2, Phase 3
14 Folic Acid Antagonists Phase 2, Phase 3
15 Hematinics Phase 2, Phase 3
16 Immunosuppressive Agents Phase 2, Phase 3
17 Nucleic Acid Synthesis Inhibitors Phase 2, Phase 3
18 Protective Agents Phase 2, Phase 3
19 Vitamin B Complex Phase 2, Phase 3
20 Folate Nutraceutical Phase 2, Phase 3
21 Vitamin B9 Nutraceutical Phase 2, Phase 3
22
Dihydrotachysterol Approved Phase 2 67-96-9 5281010 5311071
23
Nitroglycerin Approved, Investigational Phase 2 55-63-0 4510
24 Bone Density Conservation Agents Phase 2

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 Conformation of Beta Human Chorionic Gonadotropin During Chemotherapy for Choriocarcinoma Unknown status NCT00294177 Phase 4
2 Rescue Regimen and High Dose Methotrexate in Management of Presistent Gestational Trophoplastic Neoplasia Not yet recruiting NCT03280979 Phase 2, Phase 3 rescue regimen;high dose methotrxate
3 Second Curettage in Treating Patients With Persistent Non-metastatic Gestational Trophoblastic Tumors Completed NCT00521118 Phase 2
4 Avelumab in Chemo-resistant Gestational Trophoblastic Neoplasias Recruiting NCT03135769 Phase 2 Avelumab administration at 10mg/kg
5 Study of the Genetic and Epigenetic Causes of Recurrent Hydatidiform Moles Recruiting NCT01008501
6 The French National Reference Centre of GTD Recruiting NCT02892877

Search NIH Clinical Center for Partial Hydatidiform Mole

Genetic Tests for Partial Hydatidiform Mole

Anatomical Context for Partial Hydatidiform Mole

MalaCards organs/tissues related to Partial Hydatidiform Mole:

39
Uterus, Bone, Placenta, Testes, Thyroid, Liver, Lung

Publications for Partial Hydatidiform Mole

Articles related to Partial Hydatidiform Mole:

(show top 50) (show all 104)
id Title Authors Year
1
Clinical Presentation of Complete Hydatidiform Mole and Partial Hydatidiform Mole at a Regional Trophoblastic Disease Center in the United States Over the Past 2 Decades. ( 26588240 )
2016
2
Diginyc partial hydatidiform mole with increased fetal nuchal translucency and ovarian hyperstimulation syndrome. ( 27328519 )
2016
3
Histological comparison of partial hydatidiform mole and trisomy gestation specimens. ( 27575970 )
2016
4
Partial hydatidiform mole in a phenylketonuria patient treated with sapropterin dihydrochloride. ( 27898272 )
2016
5
Early Detection by Ultrasound of Partial Hydatidiform Mole With a Coexistent Live Fetus. ( 26726342 )
2015
6
Medical termination of a partial hydatidiform mole and coexisting fetus during the second trimester: A case report. ( 26788180 )
2015
7
Partial hydatidiform mole with extensive angiomatoid vessel configuration in a first trimester miscarriage. ( 25844548 )
2015
8
In patients with neoplasia after partial hydatidiform mole immunohistochemistry or genotyping is essential to differentiate partial hydatidiform mole from complete mole, histologic examination is insufficient. ( 25340289 )
2014
9
Partial hydatidiform mole diagnosis in a cat: a case report. ( 23817014 )
2014
10
Clinical utility of selective molecular genotyping for diagnosis of partial hydatidiform mole; a retrospective study from a regional trophoblastic disease unit. ( 25078332 )
2014
11
Current clinical features of complete and partial hydatidiform mole in Sweden. ( 24597287 )
2014
12
Partial hydatidiform mole following intracytoplasmic sperm injection and transfer of a cryopreserved-thawed blastocyst. ( 25093925 )
2014
13
Partial hydatidiform mole: histologic parameters in correlation with DNA genotyping. ( 23518914 )
2013
14
Ultrasonographic signs of partial hydatidiform mole. ( 23848045 )
2013
15
Partial Hydatidiform Mole With False-Negative Urine Human Chorionic Gonadatropin Test in the Emergency Department. ( 24188605 )
2013
16
Partial hydatidiform mole and coexisting viable twin pregnancy. ( 24300477 )
2013
17
Twin pregnancy and partial hydatidiform mole following in vitro fertilization and embryos transfer: a novel case of placental mosaicism. ( 23253730 )
2012
18
The diagnostic value of Ki-67, P53 and P63 in distinguishing partial Hydatidiform mole from hydropic abortion. ( 22218717 )
2012
19
Partial hydatidiform mole progression into invasive mole with lung metastasis following in vitro fertilization. ( 22740971 )
2012
20
Tetraploid partial hydatidiform mole: a case report and review of the literature. ( 22123726 )
2012
21
Recurrent partial hydatidiform mole. ( 22356040 )
2011
22
Preterm gestation along with partial hydatidiform mole and alive foetus. ( 22609510 )
2011
23
Semen analysis by electron and fluorescence microscopy in a case of partial hydatidiform mole reveals a high incidence of abnormal morphology, diploidy, and tetraploidy. ( 21354560 )
2011
24
Four repetitive partial hydatidiform moles followed by malignant transformation to an invasive mole. ( 20846070 )
2010
25
Internal iliac artery embolisation in the treatment of uncontrolled haemorrhage associated with placenta accreta and partial hydatidiform mole. ( 20373939 )
2010
26
Dizygotic twin pregnancy with a normal fetus and a nodular embryo associated with a partial hydatidiform mole. ( 20151788 )
2010
27
Recurrent partial hydatidiform mole, with a first twin pregnancy, after treatment with clomiphene citrate. ( 19499414 )
2009
28
Partial hydatidiform mole in septate uterus. ( 19655383 )
2009
29
Partial hydatidiform mole with a full-term infant. ( 19805991 )
2009
30
Thyroid storm caused by a partial hydatidiform mole. ( 18352822 )
2008
31
Partial hydatidiform mole in a 55-year-old woman: triploidy assessed by monochromosomal FISH on cultured villi. ( 19065381 )
2008
32
Triplet pregnancy with partial hydatidiform mole coexisting with two fetuses: a case report. ( 18840171 )
2008
33
Intraplacental choriocarcinoma arising in a second trimester placenta with partial hydatidiform mole. ( 18317216 )
2008
34
Shortened duration of human chorionic gonadotrophin surveillance following complete or partial hydatidiform mole: evidence for revised protocol of a UK regional trophoblastic disease unit. ( 17516969 )
2007
35
Persistent gestational trophoblastic neoplasia after partial hydatidiform mole incidence and outcome. ( 17086803 )
2006
36
Acute onset of severe hemolysis, elevated liver enzymes, and low platelet count syndrome in a patient with a partial hydatidiform mole at 17 weeks gestation. ( 16586230 )
2006
37
Recurrent partial hydatidiform mole: a report of a patient with three consecutive molar pregnancies. ( 16681793 )
2006
38
Histopathologic and immunohistochemical evaluation of blood vessels in complete and partial hydatidiform mole. ( 17253040 )
2006
39
Twin pregnancy with partial hydatidiform mole and coexistent normal fetus. ( 16753704 )
2006
40
Overdiagnosis of complete and partial hydatidiform mole in tubal ectopic pregnancies. ( 15968202 )
2005
41
Placental site trophoblastic tumour arising from a partial hydatidiform mole. ( 16112308 )
2005
42
Vasculogenesis in complete and partial hydatidiform mole pregnancies studied with CD34 immunohistochemistry. ( 15878926 )
2005
43
Twin pregnancy with partial hydatidiform mole and coexistent fetus. ( 15504073 )
2004
44
Partial hydatidiform mole following the transfer of single frozen-thawed embryo subsequent to ICSI. ( 15511346 )
2004
45
Metastatic trophoblastic disease after an initial diagnosis of partial hydatidiform mole: genotyping and chromosome in situ hybridization analysis. ( 15042675 )
2004
46
Partial hydatidiform mole along with term gestation and alive baby. ( 15762073 )
2004
47
p57kip2 is useful in the classification and differential diagnosis of complete and partial hydatidiform moles. ( 12823708 )
2003
48
Placental mesenchymal dysplasia: a report of four cases with differentiation from partial hydatidiform mole. ( 14712956 )
2003
49
Coexisting true hermaphroditism and partial hydatidiform mole developing metastatic gestational trophoblastic tumors. A case report. ( 12447683 )
2002
50
Association between Breus' mole and partial hydatidiform mole: chance or can hydropic villi precipitate placental massive subchorionic thrombosis? ( 12396900 )
2002

Variations for Partial Hydatidiform Mole

Expression for Partial Hydatidiform Mole

Search GEO for disease gene expression data for Partial Hydatidiform Mole.

Pathways for Partial Hydatidiform Mole

GO Terms for Partial Hydatidiform Mole

Sources for Partial Hydatidiform Mole

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....