MCID: PRT086
MIFTS: 28

Partial Hydatidiform Mole

Categories: Reproductive diseases, Rare diseases

Aliases & Classifications for Partial Hydatidiform Mole

MalaCards integrated aliases for Partial Hydatidiform Mole:

Name: Partial Hydatidiform Mole 55
Incomplete Hydatidiform Mole 55
Incomplete Molar Pregnancy 55
Hydatidiform Mole, Partial 69
Partial Molar Pregnancy 55

Characteristics:

Orphanet epidemiological data:

55
partial hydatidiform mole
Inheritance: Not applicable; Age of onset: Adult; Age of death: normal life expectancy;

Classifications:



External Ids:

Orphanet 55 ORPHA254693
UMLS via Orphanet 70 C0334529
ICD10 via Orphanet 33 O01.1
UMLS 69 C0334529

Summaries for Partial Hydatidiform Mole

MalaCards based summary : Partial Hydatidiform Mole, also known as incomplete hydatidiform mole, is related to hydatidiform mole, recurrent, 1 and triploidy. An important gene associated with Partial Hydatidiform Mole is NLRP7 (NLR Family Pyrin Domain Containing 7). The drugs Nitroglycerin and Dihydrotachysterol have been mentioned in the context of this disorder. Affiliated tissues include bone, placenta and testes.

Related Diseases for Partial Hydatidiform Mole

Graphical network of the top 20 diseases related to Partial Hydatidiform Mole:



Diseases related to Partial Hydatidiform Mole

Symptoms & Phenotypes for Partial Hydatidiform Mole

Drugs & Therapeutics for Partial Hydatidiform Mole

Drugs for Partial Hydatidiform Mole (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Nitroglycerin Approved, Investigational Phase 2 55-63-0 4510
2
Dihydrotachysterol Approved Phase 2 67-96-9 5311071 5281010
3 Micronutrients Phase 2
4 Trace Elements Phase 2
5 Vitamins Phase 2
6 Antibodies, Monoclonal Phase 2
7 Immunoglobulins Phase 2
8 Antibodies Phase 2
9 Bone Density Conservation Agents Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Second Curettage in Treating Patients With Persistent Non-metastatic Gestational Trophoblastic Tumors Completed NCT00521118 Phase 2
2 Avelumab in Chemo-resistant Gestational Trophoblastic Neoplasias Recruiting NCT03135769 Phase 2 Avelumab administration at 10mg/kg
3 The French National Reference Centre of GTD Recruiting NCT02892877
4 Study of the Genetic and Epigenetic Causes of Recurrent Hydatidiform Moles Recruiting NCT01008501

Search NIH Clinical Center for Partial Hydatidiform Mole

Genetic Tests for Partial Hydatidiform Mole

Anatomical Context for Partial Hydatidiform Mole

MalaCards organs/tissues related to Partial Hydatidiform Mole:

38
Bone, Placenta, Testes, Uterus, Thyroid, Liver, Lung

Publications for Partial Hydatidiform Mole

Articles related to Partial Hydatidiform Mole:

(show top 50) (show all 104)
# Title Authors Year
1
Partial hydatidiform mole in a phenylketonuria patient treated with sapropterin dihydrochloride. ( 27898272 )
2016
2
Clinical Presentation of Complete Hydatidiform Mole and Partial Hydatidiform Mole at a Regional Trophoblastic Disease Center in the United States Over the Past 2 Decades. ( 26588240 )
2016
3
Diginyc partial hydatidiform mole with increased fetal nuchal translucency and ovarian hyperstimulation syndrome. ( 27328519 )
2016
4
Histological comparison of partial hydatidiform mole and trisomy gestation specimens. ( 27575970 )
2016
5
Early Detection by Ultrasound of Partial Hydatidiform Mole With a Coexistent Live Fetus. ( 26726342 )
2015
6
Partial hydatidiform mole with extensive angiomatoid vessel configuration in a first trimester miscarriage. ( 25844548 )
2015
7
Medical termination of a partial hydatidiform mole and coexisting fetus during the second trimester: A case report. ( 26788180 )
2015
8
Clinical utility of selective molecular genotyping for diagnosis of partial hydatidiform mole; a retrospective study from a regional trophoblastic disease unit. ( 25078332 )
2014
9
In patients with neoplasia after partial hydatidiform mole immunohistochemistry or genotyping is essential to differentiate partial hydatidiform mole from complete mole, histologic examination is insufficient. ( 25340289 )
2014
10
Current clinical features of complete and partial hydatidiform mole in Sweden. ( 24597287 )
2014
11
Partial hydatidiform mole following intracytoplasmic sperm injection and transfer of a cryopreserved-thawed blastocyst. ( 25093925 )
2014
12
Partial hydatidiform mole diagnosis in a cat: a case report. ( 23817014 )
2014
13
Partial Hydatidiform Mole With False-Negative Urine Human Chorionic Gonadatropin Test in the Emergency Department. ( 24188605 )
2013
14
Partial hydatidiform mole and coexisting viable twin pregnancy. ( 24300477 )
2013
15
Ultrasonographic signs of partial hydatidiform mole. ( 23848045 )
2013
16
Partial hydatidiform mole: histologic parameters in correlation with DNA genotyping. ( 23518914 )
2013
17
The diagnostic value of Ki-67, P53 and P63 in distinguishing partial Hydatidiform mole from hydropic abortion. ( 22218717 )
2012
18
Tetraploid partial hydatidiform mole: a case report and review of the literature. ( 22123726 )
2012
19
Partial hydatidiform mole progression into invasive mole with lung metastasis following in vitro fertilization. ( 22740971 )
2012
20
Twin pregnancy and partial hydatidiform mole following in vitro fertilization and embryos transfer: a novel case of placental mosaicism. ( 23253730 )
2012
21
Recurrent partial hydatidiform mole. ( 22356040 )
2011
22
Semen analysis by electron and fluorescence microscopy in a case of partial hydatidiform mole reveals a high incidence of abnormal morphology, diploidy, and tetraploidy. ( 21354560 )
2011
23
Preterm gestation along with partial hydatidiform mole and alive foetus. ( 22609510 )
2011
24
Four repetitive partial hydatidiform moles followed by malignant transformation to an invasive mole. ( 20846070 )
2010
25
Internal iliac artery embolisation in the treatment of uncontrolled haemorrhage associated with placenta accreta and partial hydatidiform mole. ( 20373939 )
2010
26
Dizygotic twin pregnancy with a normal fetus and a nodular embryo associated with a partial hydatidiform mole. ( 20151788 )
2010
27
Recurrent partial hydatidiform mole, with a first twin pregnancy, after treatment with clomiphene citrate. ( 19499414 )
2009
28
Partial hydatidiform mole in septate uterus. ( 19655383 )
2009
29
Partial hydatidiform mole with a full-term infant. ( 19805991 )
2009
30
Intraplacental choriocarcinoma arising in a second trimester placenta with partial hydatidiform mole. ( 18317216 )
2008
31
Triplet pregnancy with partial hydatidiform mole coexisting with two fetuses: a case report. ( 18840171 )
2008
32
Thyroid storm caused by a partial hydatidiform mole. ( 18352822 )
2008
33
Partial hydatidiform mole in a 55-year-old woman: triploidy assessed by monochromosomal FISH on cultured villi. ( 19065381 )
2008
34
Shortened duration of human chorionic gonadotrophin surveillance following complete or partial hydatidiform mole: evidence for revised protocol of a UK regional trophoblastic disease unit. ( 17516969 )
2007
35
Acute onset of severe hemolysis, elevated liver enzymes, and low platelet count syndrome in a patient with a partial hydatidiform mole at 17 weeks gestation. ( 16586230 )
2006
36
Twin pregnancy with partial hydatidiform mole and coexistent normal fetus. ( 16753704 )
2006
37
Histopathologic and immunohistochemical evaluation of blood vessels in complete and partial hydatidiform mole. ( 17253040 )
2006
38
Persistent gestational trophoblastic neoplasia after partial hydatidiform mole incidence and outcome. ( 17086803 )
2006
39
Recurrent partial hydatidiform mole: a report of a patient with three consecutive molar pregnancies. ( 16681793 )
2006
40
Overdiagnosis of complete and partial hydatidiform mole in tubal ectopic pregnancies. ( 15968202 )
2005
41
Placental site trophoblastic tumour arising from a partial hydatidiform mole. ( 16112308 )
2005
42
Vasculogenesis in complete and partial hydatidiform mole pregnancies studied with CD34 immunohistochemistry. ( 15878926 )
2005
43
Metastatic trophoblastic disease after an initial diagnosis of partial hydatidiform mole: genotyping and chromosome in situ hybridization analysis. ( 15042675 )
2004
44
Partial hydatidiform mole along with term gestation and alive baby. ( 15762073 )
2004
45
Twin pregnancy with partial hydatidiform mole and coexistent fetus. ( 15504073 )
2004
46
Partial hydatidiform mole following the transfer of single frozen-thawed embryo subsequent to ICSI. ( 15511346 )
2004
47
Placental mesenchymal dysplasia: a report of four cases with differentiation from partial hydatidiform mole. ( 14712956 )
2003
48
p57kip2 is useful in the classification and differential diagnosis of complete and partial hydatidiform moles. ( 12823708 )
2003
49
Coexisting true hermaphroditism and partial hydatidiform mole developing metastatic gestational trophoblastic tumors. A case report. ( 12447683 )
2002
50
Association between Breus' mole and partial hydatidiform mole: chance or can hydropic villi precipitate placental massive subchorionic thrombosis? ( 12396900 )
2002

Variations for Partial Hydatidiform Mole

Expression for Partial Hydatidiform Mole

Search GEO for disease gene expression data for Partial Hydatidiform Mole.

Pathways for Partial Hydatidiform Mole

GO Terms for Partial Hydatidiform Mole

Sources for Partial Hydatidiform Mole

3 CDC
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10 dbSNP
11 DGIdb
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31 HPO
32 ICD10
33 ICD10 via Orphanet
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41 MeSH
42 MESH via Orphanet
43 MGI
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50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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