MCID: PST010
MIFTS: 47

Pasteurellosis malady

Infectious category

Summaries for Pasteurellosis

Sources:
8Disease Ontology, 64Wikipedia, 33MalaCards
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Disease Ontology:8 A primary bacterial infectious disease that results in systemic infection, has material basis in pasteurella multocida, which is transmitted by animal bite, scratch, or lick. the infection has symptom joint pain has symptom fever, has symptom rigors, has symptom pneumonia, has symptom meningeal irritation, and has symptom tachycardia.

MalaCards: Pasteurellosis, also known as pasteurella infectious disease, is related to tuberculosis and pasteurella multocida infection, and has symptoms including joint pain has_symptom fever, rigors and pneumonia. An important gene associated with Pasteurellosis is PI3 (peptidase inhibitor 3, skin-derived), and among its related pathways are amb2 Integrin signaling and Disease. The compounds endotoxin and 1-hydroxyphenazine have been mentioned in the context of this disorder. Affiliated tissues include whole blood, colon and lung.

Wikipedia:64 Pasteurellosis is an infection with a species of the bacteria genus Pasteurella, which is found in... more...

Aliases & Classifications for Pasteurellosis

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 57SNOMED-CT, 35MeSH, 27ICD9CM, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious


Aliases & Descriptions:

pasteurellosis 8 10
pasteurella infectious disease 8
pasteurella infections 61
pasteurella infection 8
pasteurellosis nos 8


External Ids:

Disease Ontology8 DOID:11055
MeSH35 D010326
ICD9CM27 027.2
ICD1025 A28.0

Related Diseases for Pasteurellosis

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Pasteurellosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 78)
idRelated DiseaseScoreTop Affiliating Genes
1tuberculosis29.9PDP1, ITGB2, ITGAL, ALB
2pasteurella multocida infection10.3
3cholera10.3
4pulmonary function10.1
5myocardial infarction10.0ITGAL
6influenza10.0ITGAL
7pustulosis palmaris et plantaris10.0ELANE
8gingivitis10.0ELANE
9crohn's disease10.0ALB
10alpha 1-antitrypsin deficiency10.0ELANE
11hepatitis10.0HELLS
12hepatopulmonary syndrome10.0ALB
13chorioamnionitis10.0ELANE
14cholangitis10.0ALB
15allergic rhinitis10.0MPO
16galactosemia10.0ALB
17viral hepatitis10.0SLPI, ITGAL
18mastitis10.0ALB
19dermatitis10.0ITGB2
20deficiency anemia10.0ALB
21bronchopulmonary dysplasia10.0ELANE
22capillary leak syndrome10.0ELANE
23herpes simplex10.0HELLS, SLPI
24inflammatory bowel disease10.0MPO
25rhinitis10.0ALB
26lung cancer10.0ALB
27pleuropneumonia10.0
28penicilliosis10.0
29melioidosis10.0
30encephalitozoonosis10.0
31alopecia10.0
32blepharitis10.0
33clostridium difficile10.0
34aspergillosis10.0ELANE, SLPI
35acute pancreatitis10.0ELANE, MPO
36thrombocytopenia10.0ALB, SLPI
37acute myocardial infarction10.0ITGAL, ITGB2
38leukopenia10.0ALB, MPO
39skin disease10.0ALB, MPO
40periodontal disease10.0ELANE, MPO
41extrinsic allergic alveolitis10.0ELANE, ITGAL, PI3
42membranous glomerulonephritis10.0ITGB2, ALB
43sarcoma10.0SLPI, HELLS
44bronchiectasis10.0MPO, SLPI, ELANE
45primary sclerosing cholangitis10.0MPO, SLPI, ELANE
46bronchitis10.0ELANE, SLPI, MPO
47hepatitis c10.0ALB, HELLS
48nephritis10.0MPO, ALB
49periodontitis10.0ELANE, SLPI, MPO
50neutropenia10.0ELANE, MPO, ITGAL

Graphical network of the top 20 diseases related to Pasteurellosis:



Diseases related to pasteurellosis

Clinical Features for Pasteurellosis

Sources:
8Disease Ontology
See all sources


Symptoms:

8 (see all 5)
  • joint pain has_symptom fever
  • rigors
  • pneumonia
  • meningeal irritation
  • tachycardia

Drugs & Therapeutics for Pasteurellosis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Pasteurellosis

Drug clinical trials:

Search ClinicalTrials for Pasteurellosis

Search NIH Clinical Center for Pasteurellosis

Search CenterWatch for Pasteurellosis

Genetic Tests for Pasteurellosis

Anatomical Context for Pasteurellosis

Sources:
33MalaCards
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MalaCards organs/tissues related to Pasteurellosis:

33
Whole blood, Colon, Lung, T cells, B cells

Animal Models for Pasteurellosis or affiliated genes

Sources:
28inGenious Targeting Laboratory
See all sources

Publications for Pasteurellosis

Sources:
51PubMed
See all sources

Articles related to Pasteurellosis:

(show top 50)    (show all 249)
idTitleAuthorsYear
1
A study on ovine pneumonic pasteurellosis: isolation and Identification of Pasteurellae and their antibiogram susceptibility pattern in Haramaya District, Eastern Hararghe, Ethiopia. (24289236)
2013
2
Mucosal and parenteral vaccination against pneumonic pasteurellosis in cattle with a modified-live in-frame lktA deletion mutant of Mannheimia haemolytica. (22401911)
2012
3
Bovine pasteurellosis and other bacterial infections of the respiratory tract. (20117542)
2010
4
Epidemic pasteurellosis in a bighorn sheep population coinciding with the appearance of a domestic sheep. (18436671)
2008
5
PCR analysis of Pasteurella multocida isolates from an outbreak of pasteurellosis in Indian pigs. (17669491)
2008
6
Pasteurellosis as zoonosis. (16093587)
2005
7
Sialic Acid metabolism and systemic pasteurellosis. (15731025)
2005
8
Experimental induction of pneumonic pasteurellosis in calves by intratracheal infection with Pasteurella multocida biotype A:3. (12208105)
2002
9
Ultrastructural study of ovine pulmonary pasteurellosis: involvement of neutrophils and macrophages. (11510977)
2001
10
Towards development of an edible vaccine against bovine pneumonic pasteurellosis using transgenic white clover expressing a Mannheimia haemolytica A1 leukotoxin 50 fusion protein. (11500456)
2001
11
The importance of interleukin-8 as a neutrophil chemoattractant in the lungs of cattle with pneumonic pasteurellosis. (11768129)
2001
12
The molecular epidemiology of four outbreaks of porcine pasteurellosis. (10699508)
2000
13
Intranasal vaccination of New Zealand white rabbits against pasteurellosis, using alginate-encapsulated Pasteurella multocida toxin and potassium thiocyanate extract. (10894489)
2000
14
16S rRNA gene sequence analysis of Photobacterium damselae and nested PCR method for rapid detection of the causative agent of fish pasteurellosis. (10388687)
1999
15
Pneumonic pasteurellosis associated with Pasteurella hemolytica serotype A6 in American bison (Bison bison). (9786525)
1998
16
The clinical efficacy of enrofloxacin in the treatment of experimental bovine pneumonic pasteurellosis. (9741054)
1998
17
Avian pasteurellosis: Taxonomy of the organisms involved and aspects of pathogenesis. (18483922)
1997
18
Evaluation of three experimental subunit vaccines against pneumonic pasteurellosis in cattle. (8852412)
1996
19
The goat as a model for studies of pneumonic pasteurellosis caused by Pasteurella multocida. (8791853)
1996
20
Experimental model of swine pneumonic pasteurellosis using crude Actinobacillus pleuropneumoniae cytotoxin and Pasteurella multocida given endobronchially. (8143249)
1994
21
Systemic pasteurellosis. (1413428)
1992
22
Pneumonic pasteurellosis due to P multocida in a flock of lambs in Brazil. (2028577)
1991
23
Pasteurellosis in bobwhite quail. (1953585)
1991
24
Evidence that blood-borne infection is involved in the pathogenesis of bovine pneumonic pasteurellosis. (2763414)
1989
25
Protection of lambs against experimental pneumonic pasteurellosis by transfer of immune serum. (2527437)
1989
26
The evolution of vaccines for bovine pneumonic pasteurellosis. (2672200)
1989
27
Enzyme-linked immunosorbent assay and immunoblot analysis of the immunoglobulin G response to whole-cell and lipooligosaccharide antigens of Pasteurella pneumotropica in laboratory mice with latent pasteurellosis. (2584371)
1989
28
Rabbit pasteurellosis: respiratory and renal pathology of control and immunized rabbits after challenge with Pasteurella multocida. (2520448)
1989
29
The possible involvement of immunosuppression caused by a lentivirus in the aetiology of jaagsiekte and pasteurellosis in sheep. (2848209)
1988
30
Metaphylactic use of long-acting oxytetracycline in pasteurellosis in lambs. (3201686)
1988
31
Pasteurellosis and bacteria EF 4, M5 and II J: pathogenic role in man following animal bites and bacterial sensitivity. (3509405)
1987
32
Serum cortisol levels in clinically normal feedlot lambs and clinicopathological features of septicemic pasteurellosis. (3108984)
1986
33
Antibiotic disposition in experimental pneumonic pasteurellosis: gentamicin and tylosin. (3756673)
1986
34
Chloramphenicol, lincomycin and oxytetracycline disposition in calves with experimental pneumonic pasteurellosis. (3723664)
1986
35
Serum neutralization of cytotoxin from Pasteurella haemolytica, serotype 1 and resistance to experimental bovine pneumonic pasteurellosis. (4035979)
1985
36
Preliminary studies with a live streptomycin-dependent Pasteurella multocida and Pasteurella haemolytica vaccine for the prevention of bovine pneumonic pasteurellosis. (3907804)
1985
37
Stachybotryotoxicosis as a predisposing factor of ovine systemic pasteurellosis. (6234780)
1983
38
Prevention of experimental bovine pneumonic pasteurellosis with an extract of Pasteurella haemolytica. (6315195)
1983
39
Passive protection of lambs against septicaemic pasteurellosis. (7135790)
1982
40
Protection of rabbits against experimental pasteurellosis by a streptomycin-dependent Pasteurella multocida serotype 3:A live mutant vaccine. (7333661)
1981
41
Inability of passively acquired antibody to protect lambs against experimental pasteurellosis. (227797)
1979
42
Bovine pneumonic pasteurellosis: experimental induction in vaccinated and nonvaccinated calves. (832192)
1977
43
Pasteurellosis in African grey parrots (Psittacus erithacus L.). (1200951)
1975
44
Incidents of pasteurellosis among cattle in Somalia subsequent to dual vaccination. (4666914)
1972
45
Bovine pasteurellosis. (5265807)
1969
46
Septicemic pasteurellosis (hemorrhagic septicemia) in young dairy cattle. (5190651)
1969
47
Pneumonic pasteurellosis of cattle: microbiology and immunology. (4242770)
1969
48
Foot-and-mouth disease, pasteurellosis, parasitic diseases. (5750257)
1968
49
Pasteurellosis and enzootic pneumonia in goats. (14353766)
1955
50
Bovine pasteurellosis in Southern Iowa. (13129163)
1954

Genetic Variations for Pasteurellosis

Expression for genes affiliated with Pasteurellosis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Pasteurellosis

Search GEO for disease gene expression data for Pasteurellosis.

Pathways for genes affiliated with Pasteurellosis

Sources:
38NCBI BioSystems Database, 54Reactome
See all sources

Compounds for genes affiliated with Pasteurellosis

Sources:
45Novoseek, 11DrugBank, 29IUPHAR, 50PharmGKB, 60Tocris Bioscience, 24HMDB
See all sources

Compounds related to Pasteurellosis according to GeneCards/GeneDecks:

(show top 50)    (show all 59)
idCompoundScoreTop Affiliating Genes
1endotoxin4510.4SLPI
21-hydroxyphenazine4510.4ELANE, MPO
3oxyphenbutazone45 1111.3ELANE, ALB
4nafamostat45 2911.2MPO, ELANE
5tolmetin45 1111.2MPO, ALB
6nafamostat mesilate4510.2MPO, ELANE
7cerulein4510.2MPO, ELANE
8aopp4510.2MPO, ALB
9gliclazide45 50 1112.1ALB, MPO, PDP1
10iopentol4510.1SLPI, ALB
11zymosan4510.1ITGB2, MPO, ELANE
12chloramine t4510.0ELANE, SLPI, MPO
13polysulfone4510.0ELANE, ALB, ITGB2
14dextran sulfate4510.0ELANE, ALB, MPO
15pentoxifylline45 1111.0ELANE, MPO, ITGB2
16cilomilast4510.0MPO, ELANE
17lfa70345 1111.0ITGB2, ITGAL
18fluticasone propionate45 50 60 1113.0MPO, SLPI, ELANE
19procainamide45 1110.9MPO, ITGAL, ITGB2
20sodium dodecylsulfate459.9ELANE, ALB, ITGB2, PI3
21polyacrylonitrile459.9ITGAL, ITGB2
22kininogen459.9ITGB2, MPO, ALB, ELANE
23hydralazine45 50 1111.9ITGB2, ITGAL, MPO
24cuprophan459.8ELANE, ITGAL, ITGB2
25cellulose acetate459.7ITGB2, SLPI, ALB, ELANE
26citrate459.7PDP1, SLPI, ALB, ELANE
27ampicillin45 1110.7ALB, MPO
28cytochalasin b459.6ITGB2, ITGAL, MPO, ELANE
29n-formylmethionyl-leucylphenylalanine459.6ITGB2, ITGAL, MPO, ELANE
30prednisolone45 29 1111.5ITGB2, ITGAL, MPO, ALB
31fmlp459.5ELANE, MPO, ITGAL, ITGB2
32magnesium45 11 2411.5PDP1, ITGB2, ITGAL, SLPI
33histamine45 29 2411.5PI3, ITGB2, MPO, SLPI, ALB
34alpha tocopherol459.4ELANE, ALB, ITGAL
35vitamin d459.4ELANE, ALB, SLPI, ITGB2
36leukotriene b445 60 2411.3ITGB2, ITGAL, MPO, SLPI, ELANE
37lactate459.3PDP1, ITGB2, MPO, SLPI, ALB, ELANE
38butyrate459.2ITGB2, ITGAL, MPO, SLPI
39cyclosporin a45 29 6011.2PI3, ITGB2, ITGAL, SLPI, ELANE
40fibrinogen459.2ITGB2, ITGAL, SLPI, ALB, ELANE
41oxygen45 2410.1PDP1, PI3, ITGAL, MPO, SLPI, ELANE
42superoxide45 2410.0PI3, ITGB2, ITGAL, MPO, SLPI, ELANE
43heparin45 29 11 2411.8PDP1, ITGB2, ITGAL, MPO, SLPI, ALB
44h2o2458.7HELLS, ITGB2, ITGAL, MPO, ELANE
45hyaluronic acid45 249.4ELANE, ALB, SLPI, ITGAL, ITGB2, STAB2
46cysteine458.3HELLS, PI3, ITGB2, ITGAL, SLPI, ALB
47alanine458.2HELLS, PDP1, ITGB2, ITGAL, SLPI, PELP1
48serine458.1HELLS, PDP1, PI3, ITGB2, ITGAL, MPO
49retinoic acid45 249.0HELLS, PI3, ITGB2, ITGAL, MPO, SLPI
50tyrosine457.7HELLS, PDP1, PI3, ITGB2, ITGAL, SLPI

GO Terms for genes affiliated with Pasteurellosis

Sources:
16Gene Ontology
See all sources

Cellular components related to Pasteurellosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1small ribosomal subunitGO:0159359.6RPS18, RPS28
2cytosolic small ribosomal subunitGO:0226278.9RPS18, RPS28, RPS23

Biological processes related to Pasteurellosis according to GeneCards/GeneDecks:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1response to yeastGO:00187810.2ELANE, MPO
2negative regulation of growth of symbiont in hostGO:0441309.9ELANE, MPO
3leukocyte migrationGO:0509009.4ELANE, ITGAL, ITGB2
4viral transcriptionGO:0190839.4RPS18, RPS28, RPS23
5translational terminationGO:0064159.4RPS23, RPS28, RPS18
6translational elongationGO:0064149.4RPS18, RPS28, RPS23
7viral life cycleGO:0190589.3RPS18, RPS28, RPS23
8SRP-dependent cotranslational protein targeting to membraneGO:0066149.3RPS23, RPS28, RPS18
9translational initiationGO:0064139.2RPS18, RPS28, RPS23
10nuclear-transcribed mRNA catabolic process, nonsense-mediated decayGO:0001848.9RPS23, RPS28, RPS18

Molecular functions related to Pasteurellosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:0055155.9ELANE, HELLS, STAB2, SNRPA1, ITGB2, ITGAL

Products for genes affiliated with Pasteurellosis

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Pasteurellosis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet