MCID: PST010
MIFTS: 50

Pasteurellosis malady

Infectious diseases category

Summaries for Pasteurellosis

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8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 A primary bacterial infectious disease that results in systemic infection, has material basis in pasteurella multocida, which is transmitted by animal bite, scratch, or lick. the infection has symptom joint pain has symptom fever, has symptom rigors, has symptom pneumonia, has symptom meningeal irritation, and has symptom tachycardia.

MalaCards: Pasteurellosis, also known as pasteurella infectious disease, is related to pneumonia and mastitis, and has symptoms including tachycardia, pneumonia and joint pain has_symptom fever. An important gene associated with Pasteurellosis is PI3 (peptidase inhibitor 3, skin-derived), and among its related pathways are amb2 Integrin signaling and Disease. The compounds endotoxin and 1-hydroxyphenazine have been mentioned in the context of this disorder. Affiliated tissues include lung, colon and t cells.

Wikipedia:63 Pasteurellosis is an infection with a species of the bacteria genus Pasteurella, which is found in... more...

Aliases & Classifications for Pasteurellosis

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8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 34MeSH, 27ICD9CM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Aliases & Descriptions:

pasteurellosis 8 10
pasteurella infectious disease 8
pasteurella infections 60
pasteurella infection 8
pasteurellosis nos 8


External Ids:

Disease Ontology8 DOID:11055
MeSH34 D010326
ICD9CM27 027.2
ICD1025 A28.0

Related Diseases for Pasteurellosis

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17GeneCards, 18GeneDecks
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Diseases related to Pasteurellosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 79)
idRelated DiseaseScoreTop Affiliating Genes
1pneumonia30.1PI3, MPO, SLPI, ELANE
2mastitis29.9ALB
3tuberculosis29.9PDP1, ITGB2, ITGAL, ALB
4peritonitis29.9ITGB2, MPO, SLPI, ALB
5cholera10.2
6pasteurella multocida infection10.2
7myocardial infarction10.0ITGAL
8influenza10.0ITGAL
9pustulosis palmaris et plantaris10.0ELANE
10gingivitis10.0ELANE
11crohn's disease10.0ALB
12alpha 1-antitrypsin deficiency10.0ELANE
13hepatitis10.0HELLS
14hepatopulmonary syndrome10.0ALB
15chorioamnionitis10.0ELANE
16cholangitis10.0ALB
17allergic rhinitis10.0MPO
18galactosemia10.0ALB
19viral hepatitis10.0SLPI, ITGAL
20dermatitis10.0ITGB2
21deficiency anemia10.0ALB
22bronchopulmonary dysplasia10.0ELANE
23capillary leak syndrome10.0ELANE
24herpes simplex10.0HELLS, SLPI
25inflammatory bowel disease10.0MPO
26rhinitis10.0ALB
27lung cancer10.0ALB
28aspergillosis10.0ELANE, SLPI
29acute pancreatitis10.0ELANE, MPO
30thrombocytopenia10.0ALB, SLPI
31acute myocardial infarction10.0ITGAL, ITGB2
32leukopenia10.0ALB, MPO
33skin disease10.0ALB, MPO
34periodontal disease10.0ELANE, MPO
35extrinsic allergic alveolitis10.0ELANE, ITGAL, PI3
36membranous glomerulonephritis10.0ITGB2, ALB
37sarcoma10.0SLPI, HELLS
38bronchiectasis10.0MPO, SLPI, ELANE
39primary sclerosing cholangitis10.0MPO, SLPI, ELANE
40bronchitis10.0ELANE, SLPI, MPO
41hepatitis c10.0ALB, HELLS
42nephritis10.0MPO, ALB
43periodontitis10.0ELANE, SLPI, MPO
44neutropenia10.0ELANE, MPO, ITGAL
45graves' disease10.0ITGB2, ITGAL, MPO
46diabetes mellitus10.0ALB, ITGB2, PDP1
47tropical spastic paraparesis10.0ITGB2, ITGAL
48pulmonary disease, chronic obstructive10.0ELANE, SLPI, MPO, PI3
49primary biliary cirrhosis10.0ALB, SLPI, ITGAL, PDP1
50leukocyte adhesion deficiency10.0ITGB2, ITGAL

Graphical network of the top 20 diseases related to Pasteurellosis:



Diseases related to pasteurellosis

Clinical Features for Pasteurellosis

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8Disease Ontology
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Symptoms:

8
  • tachycardia
  • pneumonia
  • joint pain has_symptom fever
  • rigors
  • meningeal irritation

Drugs & Therapeutics for Pasteurellosis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Pasteurellosis

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Anatomical Context for Pasteurellosis

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32MalaCards
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MalaCards organs/tissues related to Pasteurellosis:

32
Lung, Colon, T cells

Animal Models for Pasteurellosis or affiliated genes

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Publications for Pasteurellosis

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50PubMed
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Articles related to Pasteurellosis:

(show top 50)    (show all 249)
idTitleAuthorsYear
1
A study on ovine pneumonic pasteurellosis: isolation and Identification of Pasteurellae and their antibiogram susceptibility pattern in Haramaya District, Eastern Hararghe, Ethiopia. (24289236)
2013
2
Mucosal and parenteral vaccination against pneumonic pasteurellosis in cattle with a modified-live in-frame lktA deletion mutant of Mannheimia haemolytica. (22401911)
2012
3
Bovine pasteurellosis and other bacterial infections of the respiratory tract. (20117542)
2010
4
Epidemic pasteurellosis in a bighorn sheep population coinciding with the appearance of a domestic sheep. (18436671)
2008
5
PCR analysis of Pasteurella multocida isolates from an outbreak of pasteurellosis in Indian pigs. (17669491)
2008
6
Pasteurellosis as zoonosis. (16093587)
2005
7
Sialic Acid metabolism and systemic pasteurellosis. (15731025)
2005
8
Experimental induction of pneumonic pasteurellosis in calves by intratracheal infection with Pasteurella multocida biotype A:3. (12208105)
2002
9
Ultrastructural study of ovine pulmonary pasteurellosis: involvement of neutrophils and macrophages. (11510977)
2001
10
Towards development of an edible vaccine against bovine pneumonic pasteurellosis using transgenic white clover expressing a Mannheimia haemolytica A1 leukotoxin 50 fusion protein. (11500456)
2001
11
The importance of interleukin-8 as a neutrophil chemoattractant in the lungs of cattle with pneumonic pasteurellosis. (11768129)
2001
12
The molecular epidemiology of four outbreaks of porcine pasteurellosis. (10699508)
2000
13
Intranasal vaccination of New Zealand white rabbits against pasteurellosis, using alginate-encapsulated Pasteurella multocida toxin and potassium thiocyanate extract. (10894489)
2000
14
16S rRNA gene sequence analysis of Photobacterium damselae and nested PCR method for rapid detection of the causative agent of fish pasteurellosis. (10388687)
1999
15
Pneumonic pasteurellosis associated with Pasteurella hemolytica serotype A6 in American bison (Bison bison). (9786525)
1998
16
The clinical efficacy of enrofloxacin in the treatment of experimental bovine pneumonic pasteurellosis. (9741054)
1998
17
Avian pasteurellosis: Taxonomy of the organisms involved and aspects of pathogenesis. (18483922)
1997
18
Evaluation of three experimental subunit vaccines against pneumonic pasteurellosis in cattle. (8852412)
1996
19
The goat as a model for studies of pneumonic pasteurellosis caused by Pasteurella multocida. (8791853)
1996
20
Experimental model of swine pneumonic pasteurellosis using crude Actinobacillus pleuropneumoniae cytotoxin and Pasteurella multocida given endobronchially. (8143249)
1994
21
Systemic pasteurellosis. (1413428)
1992
22
Pneumonic pasteurellosis due to P multocida in a flock of lambs in Brazil. (2028577)
1991
23
Pasteurellosis in bobwhite quail. (1953585)
1991
24
Evidence that blood-borne infection is involved in the pathogenesis of bovine pneumonic pasteurellosis. (2763414)
1989
25
Protection of lambs against experimental pneumonic pasteurellosis by transfer of immune serum. (2527437)
1989
26
The evolution of vaccines for bovine pneumonic pasteurellosis. (2672200)
1989
27
Enzyme-linked immunosorbent assay and immunoblot analysis of the immunoglobulin G response to whole-cell and lipooligosaccharide antigens of Pasteurella pneumotropica in laboratory mice with latent pasteurellosis. (2584371)
1989
28
Rabbit pasteurellosis: respiratory and renal pathology of control and immunized rabbits after challenge with Pasteurella multocida. (2520448)
1989
29
The possible involvement of immunosuppression caused by a lentivirus in the aetiology of jaagsiekte and pasteurellosis in sheep. (2848209)
1988
30
Metaphylactic use of long-acting oxytetracycline in pasteurellosis in lambs. (3201686)
1988
31
Pasteurellosis and bacteria EF 4, M5 and II J: pathogenic role in man following animal bites and bacterial sensitivity. (3509405)
1987
32
Serum cortisol levels in clinically normal feedlot lambs and clinicopathological features of septicemic pasteurellosis. (3108984)
1986
33
Antibiotic disposition in experimental pneumonic pasteurellosis: gentamicin and tylosin. (3756673)
1986
34
Chloramphenicol, lincomycin and oxytetracycline disposition in calves with experimental pneumonic pasteurellosis. (3723664)
1986
35
Serum neutralization of cytotoxin from Pasteurella haemolytica, serotype 1 and resistance to experimental bovine pneumonic pasteurellosis. (4035979)
1985
36
Preliminary studies with a live streptomycin-dependent Pasteurella multocida and Pasteurella haemolytica vaccine for the prevention of bovine pneumonic pasteurellosis. (3907804)
1985
37
Stachybotryotoxicosis as a predisposing factor of ovine systemic pasteurellosis. (6234780)
1983
38
Prevention of experimental bovine pneumonic pasteurellosis with an extract of Pasteurella haemolytica. (6315195)
1983
39
Passive protection of lambs against septicaemic pasteurellosis. (7135790)
1982
40
Protection of rabbits against experimental pasteurellosis by a streptomycin-dependent Pasteurella multocida serotype 3:A live mutant vaccine. (7333661)
1981
41
Inability of passively acquired antibody to protect lambs against experimental pasteurellosis. (227797)
1979
42
Bovine pneumonic pasteurellosis: experimental induction in vaccinated and nonvaccinated calves. (832192)
1977
43
Pasteurellosis in African grey parrots (Psittacus erithacus L.). (1200951)
1975
44
Incidents of pasteurellosis among cattle in Somalia subsequent to dual vaccination. (4666914)
1972
45
Bovine pasteurellosis. (5265807)
1969
46
Septicemic pasteurellosis (hemorrhagic septicemia) in young dairy cattle. (5190651)
1969
47
Pneumonic pasteurellosis of cattle: microbiology and immunology. (4242770)
1969
48
Foot-and-mouth disease, pasteurellosis, parasitic diseases. (5750257)
1968
49
Pasteurellosis and enzootic pneumonia in goats. (14353766)
1955
50
Bovine pasteurellosis in Southern Iowa. (13129163)
1954

Genetic Variations for Pasteurellosis

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Expression for genes affiliated with Pasteurellosis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Pasteurellosis

Search GEO for disease gene expression data for Pasteurellosis.

Pathways for genes affiliated with Pasteurellosis

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37NCBI BioSystems Database, 53Reactome
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Compounds for genes affiliated with Pasteurellosis

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44Novoseek, 11DrugBank, 28IUPHAR, 49PharmGKB, 59Tocris Bioscience, 24HMDB
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Compounds related to Pasteurellosis according to GeneCards/GeneDecks:

(show top 50)    (show all 59)
idCompoundScoreTop Affiliating Genes
1endotoxin4410.4SLPI
21-hydroxyphenazine4410.4ELANE, MPO
3oxyphenbutazone44 1111.3ELANE, ALB
4nafamostat44 2811.2MPO, ELANE
5tolmetin44 1111.2MPO, ALB
6nafamostat mesilate4410.2MPO, ELANE
7cerulein4410.2MPO, ELANE
8aopp4410.2MPO, ALB
9gliclazide44 49 1112.1ALB, MPO, PDP1
10iopentol4410.1SLPI, ALB
11zymosan4410.1ITGB2, MPO, ELANE
12chloramine t4410.0ELANE, SLPI, MPO
13polysulfone4410.0ELANE, ALB, ITGB2
14dextran sulfate4410.0ELANE, ALB, MPO
15pentoxifylline44 1111.0ELANE, MPO, ITGB2
16cilomilast4410.0MPO, ELANE
17lfa70344 1111.0ITGB2, ITGAL
18fluticasone propionate44 49 59 1113.0MPO, SLPI, ELANE
19procainamide44 1110.9MPO, ITGAL, ITGB2
20sodium dodecylsulfate449.9ELANE, ALB, ITGB2, PI3
21polyacrylonitrile449.9ITGAL, ITGB2
22kininogen449.9ITGB2, MPO, ALB, ELANE
23hydralazine44 49 1111.9ITGB2, ITGAL, MPO
24cuprophan449.8ELANE, ITGAL, ITGB2
25cellulose acetate449.7ITGB2, SLPI, ALB, ELANE
26citrate449.7PDP1, SLPI, ALB, ELANE
27ampicillin44 1110.7ALB, MPO
28cytochalasin b449.6ITGB2, ITGAL, MPO, ELANE
29n-formylmethionyl-leucylphenylalanine449.6ITGB2, ITGAL, MPO, ELANE
30prednisolone44 28 1111.5ITGB2, ITGAL, MPO, ALB
31fmlp449.5ELANE, MPO, ITGAL, ITGB2
32magnesium44 11 2411.5PDP1, ITGB2, ITGAL, SLPI
33histamine44 28 2411.5PI3, ITGB2, MPO, SLPI, ALB
34alpha tocopherol449.4ELANE, ALB, ITGAL
35vitamin d449.4ELANE, ALB, SLPI, ITGB2
36leukotriene b444 59 2411.3ITGB2, ITGAL, MPO, SLPI, ELANE
37lactate449.3PDP1, ITGB2, MPO, SLPI, ALB, ELANE
38butyrate449.2ITGB2, ITGAL, MPO, SLPI
39cyclosporin a44 28 5911.2PI3, ITGB2, ITGAL, SLPI, ELANE
40fibrinogen449.2ITGB2, ITGAL, SLPI, ALB, ELANE
41oxygen44 2410.1PDP1, PI3, ITGAL, MPO, SLPI, ELANE
42superoxide44 2410.0PI3, ITGB2, ITGAL, MPO, SLPI, ELANE
43heparin44 28 11 2411.8PDP1, ITGB2, ITGAL, MPO, SLPI, ALB
44h2o2448.7HELLS, ITGB2, ITGAL, MPO, ELANE
45hyaluronic acid44 249.4ELANE, ALB, SLPI, ITGAL, ITGB2, STAB2
46cysteine448.3HELLS, PI3, ITGB2, ITGAL, SLPI, ALB
47alanine448.2HELLS, PDP1, ITGB2, ITGAL, SLPI, PELP1
48serine448.1HELLS, PDP1, PI3, ITGB2, ITGAL, MPO
49retinoic acid44 249.0HELLS, PI3, ITGB2, ITGAL, MPO, SLPI
50tyrosine447.7HELLS, PDP1, PI3, ITGB2, ITGAL, SLPI

GO Terms for genes affiliated with Pasteurellosis

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16Gene Ontology
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Cellular components related to Pasteurellosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1small ribosomal subunitGO:0159359.6RPS18, RPS28
2cytosolic small ribosomal subunitGO:0226278.9RPS18, RPS28, RPS23

Biological processes related to Pasteurellosis according to GeneCards/GeneDecks:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1response to yeastGO:00187810.2ELANE, MPO
2negative regulation of growth of symbiont in hostGO:0441309.9ELANE, MPO
3leukocyte migrationGO:0509009.4ELANE, ITGAL, ITGB2
4viral transcriptionGO:0190839.4RPS18, RPS28, RPS23
5translational terminationGO:0064159.4RPS23, RPS28, RPS18
6translational elongationGO:0064149.4RPS18, RPS28, RPS23
7viral life cycleGO:0190589.3RPS18, RPS28, RPS23
8SRP-dependent cotranslational protein targeting to membraneGO:0066149.3RPS23, RPS28, RPS18
9translational initiationGO:0064139.2RPS18, RPS28, RPS23
10nuclear-transcribed mRNA catabolic process, nonsense-mediated decayGO:0001848.9RPS23, RPS28, RPS18

Molecular functions related to Pasteurellosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:0055155.9ELANE, HELLS, STAB2, SNRPA1, ITGB2, ITGAL

Products for genes affiliated with Pasteurellosis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Pasteurellosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet