MCID: PST010
MIFTS: 49

Pasteurellosis malady

Infectious diseases category

Summaries for Pasteurellosis

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9Disease Ontology, 66Wikipedia, 34MalaCards
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Disease Ontology:9 A primary bacterial infectious disease that results in systemic infection, has material basis in pasteurella multocida, which is transmitted by animal bite, scratch, or lick. the infection has symptom joint pain has symptom fever, has symptom rigors, has symptom pneumonia, has symptom meningeal irritation, and has symptom tachycardia.

MalaCards: Pasteurellosis, also known as pasteurella infectious disease, is related to pneumonia and peritonitis, and has symptoms including pneumonia, tachycardia and joint pain has_symptom fever. An important gene associated with Pasteurellosis is PDP1 (pyruvate dehyrogenase phosphatase catalytic subunit 1), and among its related pathways are C-MYB transcription factor network and amb2 Integrin signaling. The compounds 1-hydroxyphenazine and nafamostat mesilate have been mentioned in the context of this disorder. Affiliated tissues include lung, colon and t cells.

Wikipedia:66 Pasteurellosis is an infection with a species of the bacteria genus Pasteurella, which is found in... more...

Aliases & Classifications for Pasteurellosis

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9Disease Ontology, 11DISEASES, 63UMLS, 28ICD9CM, 59SNOMED-CT, 36MeSH, 26ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Aliases & Descriptions:

pasteurellosis 9 11
pasteurella infectious disease 9
pasteurella infections 63
pasteurella infection 9
pasteurellosis nos 9


External Ids:

Disease Ontology9 DOID:11055
ICD9CM28 027.2
MeSH36 D010326
ICD1026 A28.0

Related Diseases for Pasteurellosis

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Sources:
18GeneCards, 19GeneDecks
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Diseases related to Pasteurellosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 51)
idRelated DiseaseScoreTop Affiliating Genes
1pneumonia30.2SLPI, ELANE, MPO
2peritonitis30.0ALB, SLPI, MPO
3cholera10.3
4pasteurella multocida infection10.2
5capillary leak syndrome10.1ELANE
6rhinitis10.1ALB
7pulmonary emphysema10.0SLPI, ELANE
8aspergillosis10.0ELANE, SLPI
9secondary hyperparathyroidism of renal origin10.0SLPI, ALB
10metabolic acidosis10.0PDP1, ALB
11hepatitis b10.0SLPI, ALB
12hyperparathyroidism10.0SLPI, ALB
13peripheral vascular disease10.0MPO, ALB
14galactosemia10.0ALB, SLPI
15hypercalcemia10.0ALB, SLPI
16adult respiratory distress syndrome10.0MPO, ELANE
17skin disease10.0MPO, ALB
18cholestasis10.0SLPI, ALB
19leukopenia10.0MPO, ALB
20primary biliary cirrhosis10.0SLPI, ALB, PDP1
21periodontal disease10.0SLPI, ELANE
22type 2 diabetes mellitus10.0SLPI, PDP1, ALB
23connective tissue disease10.0ALB, MPO
24acute pancreatitis10.0ELANE, MPO
25bronchiectasis10.0MPO, ELANE, SLPI
26primary sclerosing cholangitis10.0ELANE, SLPI, MPO
27bronchitis10.0SLPI, MPO, ELANE
28wegener's granulomatosis10.0MPO, SLPI, ELANE
29melioidosis10.0
30encephalitozoonosis10.0
31penicilliosis10.0
32cerebritis10.0
33pleuropneumonia10.0
34alopecia10.0
35blepharitis10.0
36dysentery10.0
37mastitis10.0
38mouth disease10.0
39tuberculosis10.0
40pulmonary function10.0
41newborn respiratory distress syndrome10.0SLPI, MPO, ELANE
42periodontitis10.0SLPI, ELANE, MPO
43pulmonary disease, chronic obstructive10.0MPO, ELANE, SLPI
44cork-handlers' disease10.0MPO, ELANE, SLPI
45nephritis10.0ALB, MPO
46vasculitis10.0ELANE, MPO, ALB
47pancreatitis10.0ALB, ELANE, MPO
48glomerulonephritis10.0MPO, ALB, ELANE
49primary hyperoxaluria10.0ALB, MPO
50sepsis9.9ALB, MPO, ELANE, PDP1

Graphical network of the top 20 diseases related to Pasteurellosis:



Diseases related to pasteurellosis

Symptoms for Pasteurellosis

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9Disease Ontology
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Symptoms:

9
  • pneumonia
  • tachycardia
  • joint pain has_symptom fever
  • rigors
  • meningeal irritation

Drugs & Therapeutics for Pasteurellosis

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search CenterWatch for Pasteurellosis

Genetic Tests for Pasteurellosis

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Anatomical Context for Pasteurellosis

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34MalaCards
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MalaCards organs/tissues related to Pasteurellosis:

34
Lung, Colon, T cells

Animal Models for Pasteurellosis or affiliated genes

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Publications for Pasteurellosis

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53PubMed
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Articles related to Pasteurellosis:

(show top 50)    (show all 246)
idTitleAuthorsYear
1
Seven strains of mice as potential models of bovine pasteurellosis following intranasal challenge with a bovine pneumonic strain of Pasteurella multocida A:3; comparisons of disease and pathological outcomes. (23415879)
2013
2
Mucosal and parenteral vaccination against pneumonic pasteurellosis in cattle with a modified-live in-frame lktA deletion mutant of Mannheimia haemolytica. (22401911)
2012
3
Bovine pasteurellosis and other bacterial infections of the respiratory tract. (20117542)
2010
4
Respiratory pasteurellosis: infection or colonization? (18584547)
2008
5
Effect of vaccinating lambs against pneumonic pasteurellosis under New Zealand field conditions on their weight gain and pneumonic lung lesions at slaughter. (18178931)
2008
6
Pasteurellosis as zoonosis. (16093587)
2005
7
Experimental induction of pneumonic pasteurellosis in calves by intratracheal infection with Pasteurella multocida biotype A:3. (12208105)
2002
8
Detection of antibodies against Pasteurella multocida using immunohistochemical staining in an outbreak of rabbit pasteurellosis. (11258454)
2001
9
Role of platelet-activating factor in alveolar septal injury associated with experimentally induced pneumonic pasteurellosis in calves. (10714514)
2000
10
Treatment of experimentally induced pneumonic pasteurellosis of young calves with tilmicosin. (9242998)
1997
11
Expression of tissue factor in experimental bovine pneumonic pasteurellosis and endotoxemia. (12658585)
1997
12
Increased tumor necrosis factor-alpha and interleukin-1 beta expression in the lungs of calves with experimental pneumonic pasteurellosis. (8588337)
1995
13
Pasteurellosis in elk (Cervus elaphus): DNA fingerprinting of isolates. (8560727)
1995
14
Eradication programs for pasteurellosis in rabbitries. (16466231)
1994
15
The role of concurrent haemonchosis in the development of pneumonic pasteurellosis in goats. (7975196)
1994
16
An outbreak of haemorrhagic septicaemia (septicaemic pasteurellosis) in cattle in Zimbabwe. (1305340)
1992
17
Use of an indwelling bronchial catheter model of bovine pneumonic pasteurellosis for evaluation of therapeutic efficacy of various compounds. (1524292)
1992
18
Pneumonic pasteurellosis due to P multocida in a flock of lambs in Brazil. (2028577)
1991
19
Comparison of penicillin and gentamicin for treatment of pasteurellosis in rabbits. (1849595)
1991
20
In vivo activity of orally administered antibiotics and chemotherapeutics against acute septicaemic pasteurellosis in rabbits. (2270044)
1990
21
Pneumonic pasteurellosis induced experimentally in gnotobiotic and conventional calves inoculated with Pasteurella haemolytica. (2240809)
1990
22
Treatment of experimental pasteurellosis. (2368292)
1990
23
Evidence that blood-borne infection is involved in the pathogenesis of bovine pneumonic pasteurellosis. (2763414)
1989
24
Protection of lambs against experimental pneumonic pasteurellosis by transfer of immune serum. (2527437)
1989
25
Clinical and pathological evaluation of sulbactam/ampicillin for treatment of experimental bovine pneumonic pasteurellosis. (17422967)
1988
26
Less pasteurellosis in sheep. (3716159)
1986
27
Experimentally induced pneumonic pasteurellosis: dose-response relationships and protection against natural reinfection in calves. (3002216)
1985
28
Protection of rabbits against experimental pasteurellosis by vaccination with a potassium thiocyanate extract of Pasteurella multocida. (4030090)
1985
29
Interactions of cold stress and Pasteurella haemolytica in the pathogenesis of pneumonic pasteurellosis in calves: method of induction and hematologic and pathologic changes. (6497133)
1984
30
Cellular immunity (T-cell subset using monoclonal antibody) in tuberculosis, melioidosis, pasteurellosis, penicilliosis; and role of levamisole and isoprinosine. (6084603)
1984
31
The possible role of stress in the induction of pneumonic pasteurellosis. (6089981)
1984
32
Pneumonic pasteurellosis in housed, weaned, single suckled calves. (6829153)
1983
33
Tick-borne fever and pasteurellosis in sheep. (7157612)
1982
34
Vaccination against experimental pneumonic pasteurellosis. (7101697)
1982
35
Experimental pneumonic pasteurellosis in sheep and cattle. (7090154)
1982
36
Ovine systemic pasteurellosis caused by Pasteurella haemolytica biotype T. (7463470)
1981
37
Clostridium difficile colitis in a rabbit following antibiotic therapy for pasteurellosis. (7332710)
1981
38
A streptomycin dependent live Pasteurella multocida vaccine for the prevention of rabbit pasteurellosis. (7431850)
1980
39
Response to "comments on update on pasteurellosis in young cattle". (17422081)
1980
40
Isolation of Pasteurella multocida from sporadic outbreaks of bovine pasteurellosis in Assam. (7361430)
1980
41
Investigation of factors of probable significance in the pathogenesis of pneumonic pasteurellosis in cattle. (164992)
1975
42
Pasteurellosis in African grey parrots (Psittacus erithacus L.). (1200951)
1975
43
An outbreak of pasteurellosis in lambs. (4816773)
1974
44
Bovine pasteurellosis. (5265807)
1969
45
Primary pasteurellosis in igs--studies on outbreaks on Punjab. (5389372)
1969
46
Septicemic pasteurellosis (hemorrhagic septicemia) in the American bison: a serologic survey. (5817776)
1969
47
Foot-and-mouth disease, pasteurellosis, parasitic diseases. (5750257)
1968
48
Pasteurellosis in Kenya goats due to Pasteurella haemolytica. (5624115)
1967
49
STUDIES ON AN OUTBREAK OF ACUTE SWINE PASTEURELLOSIS DUE TO PASTEURELLA MULTOCIDA TYPE B (CARTER, 1955). (14330225)
1965
50
Bovine pasteurellosis in Southern Iowa. (13129163)
1954

Variations for Pasteurellosis

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Expression for genes affiliated with Pasteurellosis

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Pasteurellosis

Search GEO for disease gene expression data for Pasteurellosis.

Pathways for genes affiliated with Pasteurellosis

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51PathCards, 39NCBI BioSystems Database, 13EMD Millipore, 56Reactome
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Compounds for genes affiliated with Pasteurellosis

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46Novoseek, 30IUPHAR, 12DrugBank, 3BitterDB, 62Tocris Bioscience, 52PharmGKB, 25HMDB
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Compounds related to Pasteurellosis according to GeneCards/GeneDecks:

(show top 50)    (show all 53)
idCompoundScoreTop Affiliating Genes
11-hydroxyphenazine4610.2MPO, ELANE
2nafamostat mesilate4610.2ELANE, MPO
3nafamostat46 3011.2MPO, ELANE
4cerulein4610.2MPO, ELANE
5fenton4610.2PDP1, MPO
6cilomilast4610.2ELANE, MPO
7oxyphenbutazone46 1211.2ALB, ELANE
8ulinastatin4610.2ELANE, MPO
9propylthiouracil46 3 1212.2MPO, ELANE
10hocl4610.2ELANE, MPO
11tolmetin46 1211.2ALB, MPO
12zymosan4610.2ELANE, MPO
13iodoacetamide4610.2MPO, ELANE
14aopp4610.2MPO, ALB
15ampicillin46 1211.1ALB, MPO
16polysulfone4610.1ALB, ELANE
17anaphylatoxin4610.1MPO, ELANE
18diisopropylfluorophosphate4610.1ALB, ELANE
19cytochalasin b4610.0ELANE, MPO
20captopril46 62 52 30 1214.0ELANE, ALB
21n-formylmethionyl-leucylphenylalanine469.9MPO, ELANE
22gliclazide46 52 1211.9PDP1, ALB, MPO
23dextran sulfate469.9MPO, ELANE, ALB
24kininogen469.9MPO, ELANE, ALB
25pentoxifylline46 1210.8ELANE, MPO
26octreotide46 62 30 1212.8ELANE, MPO
27acetylcholine46 52 30 25 1213.8MPO, ELANE, PDP1
28iopentol469.7SLPI, ALB
29sevoflurane52 46 1211.6SLPI, ALB
30saquinavir46 1210.6ALB, SLPI
31leupeptin469.6SLPI, ELANE
3225-hydroxyvitamin d469.5SLPI, ALB
33phosphorus469.5SLPI, ALB
34methacholine46 52 1211.5MPO, SLPI
35chloramine t469.4SLPI, ELANE, MPO
36fluticasone propionate46 52 62 1212.4MPO, SLPI, ELANE
37cellulose acetate469.4ALB, SLPI, ELANE
38leukotriene b446 62 2511.4MPO, SLPI, ELANE
39ascorbic acid46 2510.3MPO, SLPI, ALB
40vitamin d469.3ALB, ELANE, SLPI
41fibrinogen469.3SLPI, ALB, ELANE
42histamine46 30 2511.2SLPI, MPO, ALB
43citrate469.1PDP1, ALB, ELANE, SLPI
44nadph46 2510.1MPO, PDP1, SLPI
45oxygen46 2510.0ELANE, SLPI, PDP1, MPO
46hyaluronic acid46 259.9STAB2, ELANE, ALB, SLPI
47iron46 259.8MPO, ALB, SLPI
48lactate468.8SLPI, ELANE, ALB, PDP1, MPO
49heparin46 30 25 1211.8PDP1, ALB, ELANE, MPO, SLPI
50pge2468.7MPO, ELANE, SLPI

GO Terms for genes affiliated with Pasteurellosis

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17Gene Ontology
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Cellular components related to Pasteurellosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1secretory granuleGO:0301419.8ELANE, MPO
2cytosolic small ribosomal subunitGO:0226279.2RPS23, RPS28
3extracellular vesicular exosomeGO:0700628.1SLPI, ALB, RPS28, ELANE, MPO

Biological processes related to Pasteurellosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of growth of symbiont in hostGO:0441309.8ELANE, MPO
2response to yeastGO:0018789.5ELANE, MPO

Products for genes affiliated with Pasteurellosis

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  • Antibodies
  • Proteins
  • Lysates
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Sources for Pasteurellosis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet