MCID: PST010
MIFTS: 50

Pasteurellosis malady

Infectious diseases category

Summaries for Pasteurellosis

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8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 A primary bacterial infectious disease that results in systemic infection, has material basis in pasteurella multocida, which is transmitted by animal bite, scratch, or lick. the infection has symptom joint pain has symptom fever, has symptom rigors, has symptom pneumonia, has symptom meningeal irritation, and has symptom tachycardia.

MalaCards: Pasteurellosis, also known as pasteurella infectious disease, is related to pneumonia and mastitis, and has symptoms including joint pain has_symptom fever, rigors and pneumonia. An important gene associated with Pasteurellosis is PI3 (peptidase inhibitor 3, skin-derived), and among its related pathways are amb2 Integrin signaling and Disease. The compounds endotoxin and 1-hydroxyphenazine have been mentioned in the context of this disorder. Affiliated tissues include lung, colon and t cells.

Wikipedia:63 Pasteurellosis is an infection with a species of the bacteria genus Pasteurella, which is found in... more...

Aliases & Classifications for Pasteurellosis

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8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 34MeSH, 27ICD9CM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Aliases & Descriptions:

pasteurellosis 8 10
pasteurella infectious disease 8
pasteurella infections 60
pasteurella infection 8
pasteurellosis nos 8


External Ids:

Disease Ontology8 DOID:11055
MeSH34 D010326
ICD9CM27 027.2
ICD1025 A28.0

Related Diseases for Pasteurellosis

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17GeneCards, 18GeneDecks
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Diseases related to Pasteurellosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 79)
idRelated DiseaseScoreTop Affiliating Genes
1pneumonia30.1PI3, MPO, SLPI, ELANE
2mastitis29.9ALB
3tuberculosis29.9PDP1, ITGB2, ITGAL, ALB
4peritonitis29.9ITGB2, MPO, SLPI, ALB
5cholera10.2
6pasteurella multocida infection10.2
7myocardial infarction10.0ITGAL
8influenza10.0ITGAL
9pustulosis palmaris et plantaris10.0ELANE
10gingivitis10.0ELANE
11crohn's disease10.0ALB
12alpha 1-antitrypsin deficiency10.0ELANE
13hepatitis10.0HELLS
14hepatopulmonary syndrome10.0ALB
15chorioamnionitis10.0ELANE
16cholangitis10.0ALB
17allergic rhinitis10.0MPO
18galactosemia10.0ALB
19viral hepatitis10.0SLPI, ITGAL
20dermatitis10.0ITGB2
21deficiency anemia10.0ALB
22bronchopulmonary dysplasia10.0ELANE
23capillary leak syndrome10.0ELANE
24herpes simplex10.0HELLS, SLPI
25inflammatory bowel disease10.0MPO
26rhinitis10.0ALB
27lung cancer10.0ALB
28aspergillosis10.0ELANE, SLPI
29acute pancreatitis10.0ELANE, MPO
30thrombocytopenia10.0ALB, SLPI
31acute myocardial infarction10.0ITGAL, ITGB2
32leukopenia10.0ALB, MPO
33skin disease10.0ALB, MPO
34periodontal disease10.0ELANE, MPO
35extrinsic allergic alveolitis10.0ELANE, ITGAL, PI3
36membranous glomerulonephritis10.0ITGB2, ALB
37sarcoma10.0SLPI, HELLS
38bronchiectasis10.0MPO, SLPI, ELANE
39primary sclerosing cholangitis10.0MPO, SLPI, ELANE
40bronchitis10.0ELANE, SLPI, MPO
41hepatitis c10.0ALB, HELLS
42nephritis10.0MPO, ALB
43periodontitis10.0ELANE, SLPI, MPO
44neutropenia10.0ELANE, MPO, ITGAL
45graves' disease10.0ITGB2, ITGAL, MPO
46diabetes mellitus10.0ALB, ITGB2, PDP1
47tropical spastic paraparesis10.0ITGB2, ITGAL
48pulmonary disease, chronic obstructive10.0ELANE, SLPI, MPO, PI3
49primary biliary cirrhosis10.0ALB, SLPI, ITGAL, PDP1
50leukocyte adhesion deficiency10.0ITGB2, ITGAL

Graphical network of the top 20 diseases related to Pasteurellosis:



Diseases related to pasteurellosis

Clinical Features for Pasteurellosis

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8Disease Ontology
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Symptoms:

8
  • joint pain has_symptom fever
  • rigors
  • pneumonia
  • meningeal irritation
  • tachycardia

Drugs & Therapeutics for Pasteurellosis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Pasteurellosis

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Anatomical Context for Pasteurellosis

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32MalaCards
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MalaCards organs/tissues related to Pasteurellosis:

32
Lung, Colon, T cells

Animal Models for Pasteurellosis or affiliated genes

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Publications for Pasteurellosis

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50PubMed
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Articles related to Pasteurellosis:

(show top 50)    (show all 249)
idTitleAuthorsYear
1
Septicaemic pasteurellosis in free-range pigs associated with an unusual biovar 13 of Pasteurella multocida. (24011940)
2013
2
Life-threatening respiratory pasteurellosis associated with palliative pet care. (22238163)
2012
3
Neonatal pasteurellosis: a review of reported cases. (19208671)
2009
4
Efficacy of danofloxacin in the treatment of pneumonic pasteurellosis in specific pathogen-free lambs. (17545648)
2007
5
Side effects in sea bass (Dicentrarchus labrax L.) due to intraperitoneal vaccination against vibriosis and pasteurellosis. (15722227)
2005
6
Diabetes in patients with pasteurellosis. (16191890)
2005
7
Pasteurellosis in Atlantic salmon, Salmo salar L.: immunohistochemistry of the naturally-occurring disease. (12899413)
2003
8
Protective immunity against pasteurellosis in cattle, induced by Pasteurella haemolytica ghosts. (12615438)
2003
9
Detection of antibodies against Pasteurella multocida using immunohistochemical staining in an outbreak of rabbit pasteurellosis. (11258454)
2001
10
Septicemic pasteurellosis in free-ranging neonatal pronghorn in Oregon. (10813624)
2000
11
Evaluation of structural and functional alterations of circulating neutrophils in calves with experimentally induced pneumonic pasteurellosis. (10791946)
1999
12
Acute septicaemic pasteurellosis in Vietnamese pigs. (9850999)
1998
13
Role of tissue factor in intra-alveolar fibrin deposition and coagulopathy associated with pneumonic pasteurellosis in cattle. (8989492)
1997
14
Increased tumor necrosis factor-alpha and interleukin-1 beta expression in the lungs of calves with experimental pneumonic pasteurellosis. (8588337)
1995
15
Pasteurellosis in elk (Cervus elaphus): DNA fingerprinting of isolates. (8560727)
1995
16
Administration of a bolus formulation of baquiloprim and sulphadimidine to calves: plasma concentration--time profiles and efficacy in suppressing experimental pneumonic pasteurellosis. (8017029)
1994
17
Efficacy of Pasteurella haemolytica subunit antigens in a goat model of pasteurellosis. (8250389)
1993
18
Prevention of pasteurellosis. (1576523)
1992
19
Spontaneous pasteurellosis in captive Rocky Mountain bighorn sheep (Ovis canadensis canadensis): clinical, laboratory, and epizootiological observations. (1758018)
1991
20
The effects of stressful exercise on leukocytes in cattle with experimental pneumonic pasteurellosis. (1882513)
1991
21
Treatment of experimental pasteurellosis. (2368292)
1990
22
Somnogenic, pyrogenic, and hematologic effects of experimental pasteurellosis in rabbits. (2309940)
1990
23
Treatment of experimental pasteurellosis in lambs with clavulanic acid and amoxycillin. (2140474)
1990
24
Presence of bacterial glycocalyx and fimbriae on Pasteurella haemolytica in feedlot cattle with pneumonic pasteurellosis. (2565756)
1989
25
Serum and tissue concentrations of erythromycin in calves with induced pneumonic pasteurellosis. (2774339)
1989
26
Efficacy of a live Pasteurella multocida vaccine for the prevention of experimentally induced bovine pneumonic pasteurellosis. (2558441)
1989
27
Sheep herpesvirus does not increase susceptibility to pneumonic pasteurellosis. (2549678)
1989
28
Antibody complement-dependent bacteriolysis in experimentally induced pasteurellosis in mice. (2729722)
1989
29
Less pasteurellosis in sheep. (3716159)
1986
30
Serum antibodies to antigens derived from a saline extract of Pasteurella haemolytica: correlation with resistance to experimental bovine pneumonic pasteurellosis. (3909624)
1985
31
Experimental reproduction of septicemic pasteurellosis in feedlot lambs: bacteriologic and pathologic examinations. (2982297)
1985
32
Bovine pneumonic pasteurellosis: model for Pasteurella haemolytica- and Pasteurella multocida-induced pneumonia in cattle. (6395732)
1984
33
Bovine pneumonic pasteurellosis: effect of culture age of Pasteurella haemolytica used as a live vaccine. (6395734)
1984
34
Naturally occurring pasteurellosis in laboratory rabbits: chemical and serological studies of whole cells and lipopolysaccharides of Pasteurella multocida. (6715048)
1984
35
Pneumonic pasteurellosis in housed, weaned, single suckled calves. (6829153)
1983
36
Comparison of two oxytetracycline formulations in the treatment of laboratory-induced pasteurellosis of pigs. (6870001)
1983
37
Vaccination against experimental pneumonic pasteurellosis. (7101697)
1982
38
Ovine pasteurellosis vaccines. (7147638)
1982
39
Ovine systemic pasteurellosis caused by Pasteurella haemolytica biotype T. (7463470)
1981
40
Response to "comments on update on pasteurellosis in young cattle". (17422081)
1980
41
Comments on "update on pasteurellosis in young cattle". (7438009)
1980
42
Serotypes of Pasteurella haemolytica in ovine pasteurellosis. (841198)
1977
43
Pasteurellosis in reindeer in northern Norway. A contribution of its epidemiology. (1015481)
1976
44
An outbreak of pasteurellosis in lambs. (4816773)
1974
45
Bovine parainfluenza Type 3 virus infection and pasteurellosis. (4342867)
1971
46
Septicemic pasteurellosis (hemorrhagic septicemia) in the American bison: a serologic survey. (5817776)
1969
47
STUDIES ON AN OUTBREAK OF ACUTE SWINE PASTEURELLOSIS DUE TO PASTEURELLA MULTOCIDA TYPE B (CARTER, 1955). (14330225)
1965
48
Septicemic pasteurellosis in lambs. (13800459)
1959
49
Pasteurellosis in coots. (13150765)
1954
50
Some Comments on Pasteurellosis. (17648555)
1952

Genetic Variations for Pasteurellosis

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Expression for genes affiliated with Pasteurellosis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Pasteurellosis

Search GEO for disease gene expression data for Pasteurellosis.

Pathways for genes affiliated with Pasteurellosis

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37NCBI BioSystems Database, 53Reactome
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Compounds for genes affiliated with Pasteurellosis

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44Novoseek, 11DrugBank, 28IUPHAR, 49PharmGKB, 59Tocris Bioscience, 24HMDB
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Compounds related to Pasteurellosis according to GeneCards/GeneDecks:

(show top 50)    (show all 59)
idCompoundScoreTop Affiliating Genes
1endotoxin4410.4SLPI
21-hydroxyphenazine4410.4ELANE, MPO
3oxyphenbutazone44 1111.3ALB, ELANE
4nafamostat mesilate4410.2ELANE, MPO
5nafamostat44 2811.2ELANE, MPO
6tolmetin44 1111.2MPO, ALB
7cerulein4410.2MPO, ELANE
8aopp4410.2ALB, MPO
9gliclazide44 49 1112.1PDP1, MPO, ALB
10iopentol4410.1SLPI, ALB
11zymosan4410.1ITGB2, ELANE, MPO
12chloramine t4410.0MPO, SLPI, ELANE
13polysulfone4410.0ITGB2, ALB, ELANE
14dextran sulfate4410.0MPO, ELANE, ALB
15pentoxifylline44 1111.0MPO, ITGB2, ELANE
16cilomilast4410.0MPO, ELANE
17lfa70344 1111.0ITGAL, ITGB2
18fluticasone propionate44 49 59 1113.0SLPI, ELANE, MPO
19procainamide44 1110.9ITGAL, MPO, ITGB2
20sodium dodecylsulfate449.9ELANE, PI3, ITGB2, ALB
21polyacrylonitrile449.9ITGB2, ITGAL
22kininogen449.9ELANE, ITGB2, MPO, ALB
23hydralazine44 49 1111.9MPO, ITGB2, ITGAL
24cuprophan449.8ITGB2, ITGAL, ELANE
25cellulose acetate449.7ELANE, ALB, ITGB2, SLPI
26citrate449.7ALB, ELANE, SLPI, PDP1
27ampicillin44 1110.7ALB, MPO
28cytochalasin b449.6MPO, ITGAL, ELANE, ITGB2
29n-formylmethionyl-leucylphenylalanine449.6ELANE, MPO, ITGAL, ITGB2
30prednisolone44 28 1111.5ALB, MPO, ITGAL, ITGB2
31fmlp449.5MPO, ELANE, ITGAL, ITGB2
32magnesium44 11 2411.5ITGAL, ITGB2, PDP1, SLPI
33histamine44 28 2411.5ITGB2, PI3, ALB, MPO, SLPI
34alpha tocopherol449.4ALB, ELANE, ITGAL
35vitamin d449.4ELANE, ITGB2, SLPI, ALB
36leukotriene b444 59 2411.3MPO, ITGAL, ITGB2, ELANE, SLPI
37lactate449.3PDP1, ITGB2, MPO, SLPI, ELANE, ALB
38butyrate449.2SLPI, MPO, ITGAL, ITGB2
39cyclosporin a44 28 5911.2ELANE, SLPI, ITGAL, ITGB2, PI3
40fibrinogen449.2ITGB2, ALB, ELANE, SLPI, ITGAL
41oxygen44 2410.1SLPI, PDP1, PI3, ITGAL, MPO, ELANE
42superoxide44 2410.0SLPI, MPO, ITGAL, ITGB2, PI3, ELANE
43heparin44 28 11 2411.8SLPI, MPO, ITGAL, ELANE, ITGB2, PDP1
44h2o2448.7HELLS, ELANE, MPO, ITGAL, ITGB2
45hyaluronic acid44 249.4ELANE, ALB, SLPI, ITGAL, ITGB2, STAB2
46cysteine448.3ELANE, PI3, ITGB2, ITGAL, SLPI, ALB
47alanine448.2ALB, SLPI, ITGAL, PELP1, ITGB2, HELLS
48serine448.1ITGB2, PI3, MPO, SLPI, ELANE, HELLS
49retinoic acid44 249.0ELANE, MPO, ITGB2, PI3, HELLS, ITGAL
50tyrosine447.7ITGB2, PELP1, SLPI, ITGAL, PI3, PDP1

GO Terms for genes affiliated with Pasteurellosis

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16Gene Ontology
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Cellular components related to Pasteurellosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1small ribosomal subunitGO:0159359.6RPS18, RPS28
2cytosolic small ribosomal subunitGO:0226278.9RPS18, RPS28, RPS23

Biological processes related to Pasteurellosis according to GeneCards/GeneDecks:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1response to yeastGO:00187810.2ELANE, MPO
2negative regulation of growth of symbiont in hostGO:0441309.9ELANE, MPO
3leukocyte migrationGO:0509009.4ELANE, ITGAL, ITGB2
4viral transcriptionGO:0190839.4RPS18, RPS28, RPS23
5translational terminationGO:0064159.4RPS23, RPS28, RPS18
6translational elongationGO:0064149.4RPS18, RPS28, RPS23
7viral life cycleGO:0190589.3RPS18, RPS28, RPS23
8SRP-dependent cotranslational protein targeting to membraneGO:0066149.3RPS23, RPS28, RPS18
9translational initiationGO:0064139.2RPS18, RPS28, RPS23
10nuclear-transcribed mRNA catabolic process, nonsense-mediated decayGO:0001848.9RPS23, RPS28, RPS18

Molecular functions related to Pasteurellosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:0055155.9ELANE, HELLS, STAB2, SNRPA1, ITGB2, ITGAL

Products for genes affiliated with Pasteurellosis

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  • Antibodies
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Sources for Pasteurellosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet