Aliases & Classifications for Patellofemoral Pain Syndrome

MalaCards integrated aliases for Patellofemoral Pain Syndrome:

Name: Patellofemoral Pain Syndrome 12 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:14284
MeSH 42 D046788
UMLS 69 C0877149

Summaries for Patellofemoral Pain Syndrome

MalaCards based summary : Patellofemoral Pain Syndrome is related to chronic canaliculitis and pyloric stenosis, and has symptoms including arthralgia and metatarsalgia. An important gene associated with Patellofemoral Pain Syndrome is PRF1 (Perforin 1), and among its related pathways/superpathways are Toxoplasmosis and TNF signaling pathway. The drugs Acetaminophen and Analgesics have been mentioned in the context of this disorder. Affiliated tissues include bone and testes, and related phenotypes are hematopoietic system and immune system

Wikipedia : 72 Patellofemoral pain syndrome (PFPS), also known as patellar overload syndrome and runner\'s knee, is a... more...

Related Diseases for Patellofemoral Pain Syndrome

Diseases related to Patellofemoral Pain Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

id Related Disease Score Top Affiliating Genes
1 chronic canaliculitis 10.3 KCNK6 LY96
2 pyloric stenosis 10.1 LY86 LY96
3 bejel 10.1 LY86 LY96
4 hyperlucent lung 9.8 LY86 LY96
5 chondromalacia 9.8
6 conjunctivitis 9.8
7 acute mountain sickness 9.8
8 leopard syndrome 3.9 ANKLE1 EDN2 FOS FUT2 JUN KCNK6

Graphical network of the top 20 diseases related to Patellofemoral Pain Syndrome:



Diseases related to Patellofemoral Pain Syndrome

Symptoms & Phenotypes for Patellofemoral Pain Syndrome

UMLS symptoms related to Patellofemoral Pain Syndrome:


arthralgia, metatarsalgia

MGI Mouse Phenotypes related to Patellofemoral Pain Syndrome:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.65 ANKLE1 EDN2 FOS JUN LY86 LY96
2 immune system MP:0005387 9.36 FOS FUT2 JUN LY86 LY96 MMP8

Drugs & Therapeutics for Patellofemoral Pain Syndrome

Drugs for Patellofemoral Pain Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 34)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetaminophen Approved Phase 4 103-90-2 1983
2 Analgesics Phase 4
3 Analgesics, Non-Narcotic Phase 4
4 Antipyretics Phase 4
5 Peripheral Nervous System Agents Phase 4,Phase 3
6
Lidocaine Approved, Vet_approved Phase 3 137-58-6 3676
7
Acetylcholine Approved Phase 3 51-84-3 187
8
Imidacloprid Vet_approved Phase 3 105827-78-9 86418
9 abobotulinumtoxinA Phase 3
10 Botulinum Toxins Phase 3
11 Botulinum Toxins, Type A Phase 3
12 Cholinergic Agents Phase 3
13 Neuromuscular Agents Phase 3
14 Neurotransmitter Agents Phase 3
15 onabotulinumtoxinA Phase 3
16
Hyaluronic acid Approved, Vet_approved Phase 2 9004-61-9 53477741 24759
17 Adjuvants, Immunologic Phase 2
18 Hylan Phase 2
19 Protective Agents Phase 2
20 Viscosupplements Phase 2
21 Povidone-iodine Approved 25655-41-8
22
Benzocaine Approved 1994-09-7, 94-09-7 2337
23
Oxymetazoline Approved 1491-59-4 4636
24
Phenylephrine Approved 59-42-7 6041
25
Ethanol Approved 64-17-5 702
26
Menthol Approved 2216-51-5 16666
27
Sulfamethazine Approved, Vet_approved 57-68-1 5327
28
Bupivacaine Approved, Investigational 2180-92-9, 38396-39-3 2474
29 tannic acid Approved, Nutraceutical
30
s 1 (combination)
31 Antipruritics
32 Dermatologic Agents
33 Anesthetics
34 Astragalus Nutraceutical

Interventional clinical trials:

(show top 50) (show all 81)

id Name Status NCT ID Phase Drugs
1 Close Kinect Chain Exercise With Kinesio Taping in the Management of Patellofemoral Pain Syndrome Unknown status NCT02241148 Phase 4 Acetaminophen 500mg
2 Rehabilitation With Patterned Electrical Neuromuscular Stimulation for Patients With Patellofemoral Pain Unknown status NCT02441712 Phase 2, Phase 3
3 Diacutaneous Fibrolysis and Patellofemoral Pain Syndrome Completed NCT02379364 Phase 3
4 A Clinical Study in the Use of Orthotics in Treating Pain in the Front of the Knee Completed NCT00118521 Phase 3
5 Comparing the Outcome of Electrical Stimulation and Physical Therapy in Patellofemoral Pain Syndrome Recruiting NCT03184545 Phase 3
6 Botox for Non-surgical Lateral Release in Patellofemoral Pain Terminated NCT00496964 Phase 3 Botulinum toxin A + exercise;Placebo
7 Comparison of The Clinical Effects Between Different Physical Therapy Tools in Patellofemoral Pain Patients Unknown status NCT00451347 Phase 1, Phase 2
8 Treatment for Patellofemoral Pain Syndrome Using Footwear Completed NCT01332110 Phase 1, Phase 2
9 Comparison of Two Protocols for Patellofemoral Pain Syndrome Completed NCT01691170 Phase 1, Phase 2
10 Assessing Foot Injuries in Infantry Recruits Wearing Different Boots Completed NCT02810002 Phase 1, Phase 2
11 Intra-articular Hyaluronic Acid Injection for Therapy-resistant Patellofemoral Pain Syndrome Recruiting NCT02613247 Phase 2
12 Comparisons of Mechanical Properties of Tendon Structures Unknown status NCT00451087 Phase 1
13 Effect of Hip Adduction Combination With Knee Extension Exercise on Morphology of Quadriceps Muscles, Pain and Functional Outcomes in Patients With PFPS Unknown status NCT00166777 Phase 1
14 Neural Mechanisms of Muscle Control in Individuals With Knee Pain Not yet recruiting NCT02854774 Phase 1
15 Foot Orthoses in Patellofemoral Pain Syndrome: a Prospective Randomized Study of Morpho-specific Versus Placebo Orthoses Unknown status NCT02250144
16 Selective Neuromuscular Electrical Stimulation on VMO Unknown status NCT02548988
17 Morphology of the VMO in Patients With PFPS and Healthy Young Adults--A Sonographic Study Unknown status NCT00173147
18 The Role of Quadriceps Contraction in Patellar Repositioning - a Computed Tomography Study Unknown status NCT00760136 Early Phase 1
19 The Effect of Muscle Strengthening Associated With Neuromuscular Stimulus in Patients With Patellofemoral Pain During Negotiating Stairs Unknown status NCT02591680
20 Randomized Evaluation of the Efficacy of Synvisc-One® for the Treatment of Patellofemoral Chondromalacia Unknown status NCT01771952
21 Prevention of Injuries by an Exercise Program – a RCT Unknown status NCT00348647
22 Comparison Study of Two Chiropractic Treatment Protocols for Knee Pain Due to Patellofemoral Pain Syndrome Completed NCT00401050
23 Comparison of Effects of Mobilization With Movement and Kinesiotaping in Patellofemoral Pain Syndrome Completed NCT02707679
24 Efficiency of Patellar Taping in Treatment of Patellofemoral Pain Syndrome Completed NCT01504100
25 Dosage-dependence of Graded Exercise Therapy in Patients With Patellofemoral Pain Syndrome. Completed NCT01290705
26 Early Intervention for Adolescents With Patellofemoral Pain Syndrome Completed NCT01438762
27 Correlation Between the Amplitude of Ankle Dorsiflexion and Occurrence of Patellofemoral Pain Syndrome Completed NCT03213015
28 The Evaluation of a Novel Treatment Algorithm for Patients With Patellofemoral Syndrome Completed NCT01767246
29 Effect of Lower Back Treatment in People With Patellofemoral Pain Syndrome. Completed NCT01975311
30 Kinematics of Lower Limb, Pain and Function of the Women With Patellofemoral Pain Syndrome Completed NCT01804608
31 Effects of Lumbopelvic Manipulation on Hip and Knee Neuromuscular Activity Completed NCT01637480
32 Manual Therapy and Dry Needling in Patellofemoral Syndrome Completed NCT02514005
33 Comparing Rehabilitation Programs for Patellofemoral Pain Syndrome Completed NCT00445224
34 Effects of Hip Abductor and External Rotator Strength Training in Patients With Patellofemoral Pain Syndrome Completed NCT00736736
35 Patellar Taping on Proprioceptive Exercises in Young Women With Patellofemoral Pain Syndrome Completed NCT02322515
36 The Effect of Kinesio Taping® on Motor Control in Patients With Patellofemoral Pain Syndrome Completed NCT03117205
37 The Effects of Dry Needling & Kinesio Tape on Anterior Knee Pain Completed NCT02118246
38 The Effects and Predictors of Patella Taping in the Treatment of Patellafemoral Pain Syndrome Completed NCT01727596
39 Investigation of Muscle Activity Pattern of Gluteus Medius and Tensor Fascia Lata in Patients With PFPS Completed NCT00451438
40 Vasti Control of Patellofemoral Kinematics in Asymptomatic Volunteer Completed NCT00978003
41 Conventional Home Exercise Programs Versus Electronic Home Exercise Versus Artificial Intelligence "Virtual Therapy" for Anterior Knee Pain Completed NCT01696162
42 Effects of Hip and Knee Exercises on Knee Pain in Young Adult Females With Long-standing Patellofemoral Pain Completed NCT03054701
43 Running Study for Runners With Chronic Knee Pain Completed NCT02567123
44 Dynamic Quadriceps Muscle Stimulation for Treatment of Patellofemoral Pain Completed NCT02243332
45 The Movement Control Training Associated With Conventional Physical Therapy is More Effective Than Conventional Physical Therapy Alone in Pain and Functional Performance? Completed NCT02624245
46 In Vivo Arthroscopic Behavior of the Infrapatellar Plica of the Knee Completed NCT00643487
47 5 Year Follow-up of Adolescents With Knee Pain Completed NCT02873143
48 Changes in Quadriceps Function Following Local or Distant Interventions in Individuals With Patellofemoral Pain Completed NCT01434966
49 Live Feedback to Increase Adherence in Adolescents With Patellofemoral Pain Completed NCT02674841
50 A Controlled Trial on Recreational Runners With Patellofemoral Pain Completed NCT02352909

Search NIH Clinical Center for Patellofemoral Pain Syndrome

Cochrane evidence based reviews: patellofemoral pain syndrome

Genetic Tests for Patellofemoral Pain Syndrome

Anatomical Context for Patellofemoral Pain Syndrome

MalaCards organs/tissues related to Patellofemoral Pain Syndrome:

39
Bone, Testes

Publications for Patellofemoral Pain Syndrome

Articles related to Patellofemoral Pain Syndrome:

(show top 50) (show all 340)
id Title Authors Year
1
Effectiveness of Manual Therapy Combined With Physical Therapy in Treatment of Patellofemoral Pain Syndrome: Systematic Review. ( 28559754 )
2017
2
Patellar bracing affects sEMG activity of leg and thigh muscles during stance phase in patellofemoral pain syndrome. ( 28697399 )
2017
3
Systematic Review of the Effect of Taping Techniques on Patellofemoral Pain Syndrome. ( 28617653 )
2017
4
Comparison of ischemic compression and lumbopelvic manipulation as trigger point therapy for patellofemoral pain syndrome in young adults: A double-blind randomized clinical trial. ( 28750964 )
2017
5
Carryover effect of hip and knee exercises program on functional performance in individuals with patellofemoral pain syndrome. ( 28878459 )
2017
6
Core Neuromuscular Training; a Physical Activity Intervention for Individuals with Patellofemoral Pain Syndrome: 3294 Board #359 June 3, 3: 30 PM - 5: 00 PM. ( 27361863 )
2016
7
TIBIOFEMORAL JOINT MOBILIZATION IN THE SUCCESSFUL MANAGEMENT OF PATELLOFEMORAL PAIN SYNDROME: A CASE REPORT. ( 27274430 )
2016
8
Long term effect of selective muscle strengthening in athletes with patellofemoral pain syndrome. ( 27104322 )
2016
9
Short-term effects of kinesio tape on joint position sense, isokinetic measurements, and clinical parameters in patellofemoral pain syndrome. ( 27512259 )
2016
10
The effect of hip and knee exercises on pain, function, and strength in patientswith patellofemoral pain syndrome: a randomized controlled trial. ( 27511483 )
2016
11
Comparative evaluation of ambulation patterns and isokinetic muscle strength for the application of rehabilitation exercise in patients with patellofemoral pain syndrome. ( 28174434 )
2016
12
Kinematic and electromyographic analysis in patients with patellofemoral pain syndrome during single leg triple hop test. ( 27470227 )
2016
13
Mcconnell's patellar taping does not alter knee and hip muscle activation differences during proprioceptive exercises: A randomized placebo-controlled trial in women with patellofemoral pain syndrome. ( 27693990 )
2016
14
Evaluating the potential synergistic benefit of a realignment brace on patients receiving exercise therapy for patellofemoral pain syndrome: a randomized clinical trial. ( 27146819 )
2016
15
Effectiveness of core muscle strengthening for improving pain and dynamic balance among female patients with patellofemoral pain syndrome. ( 27313363 )
2016
16
Short Arc Training Effects On Knee Strength, Pain, Functional Performance With Patellofemoral Pain Syndrome Patients: 1619 Board #272 June 2, 8: 00 AM - 9: 30 AM. ( 27360538 )
2016
17
Greek cultural adaption and validation of the Kujala anterior knee pain scale in patients with patellofemoral pain syndrome. ( 27049481 )
2016
18
Is there a role of pulsed electromagnetic fields in management of patellofemoral pain syndrome? Randomized controlled study at one year follow-up. ( 26756278 )
2016
19
The validity and reliability of the Thai version of the Kujala score for patients with patellofemoral pain syndrome. ( 26729626 )
2016
20
The Effect of Patellofemoral Pain Syndrome on Gait Parameters: A Literature Review. ( 27847840 )
2016
21
The immediate effect of lumbopelvic manipulation on EMG of vasti and gluteus medius in athletes with patellofemoral pain syndrome: A randomized controlled trial. ( 26995778 )
2016
22
Predictors for identifying patients with patellofemoral pain syndrome responding to femoral nerve mobilization. ( 25576086 )
2015
23
Anterior knee pain caused by patellofemoral pain syndrome can be relieved by Botulinum toxin type A injection. ( 25683309 )
2015
24
Exercise for treating patellofemoral pain syndrome. An abridged version of Cochrane Systematic Review. ( 26158920 )
2015
25
Clijsen R, Fuchs J, Taeymans J. Effectiveness of exercise therapy in treatment of patients with patellofemoral pain syndrome: systematic review and meta-analysis. Phys Ther. 2014;94:1697-1708. ( 26031469 )
2015
26
Effectiveness of therapeutic physical exercise in the treatment of patellofemoral pain syndrome: a systematic review. ( 26311988 )
2015
27
Effectiveness of hip muscle strengthening in patellofemoral pain syndrome patients: a systematic review. ( 26039034 )
2015
28
"Measurement properties of patient-reported outcome measures (PROMS) in patellofemoral pain syndrome: A systematic review". Green etA al. (in press corrected proof). ( 25660820 )
2015
29
The relationship between quadriceps strength and joint position sense, functional outcome and painful activities in patellofemoral pain syndrome. ( 25869907 )
2015
30
The Effects of a Multimodal Rehabilitation Program on Symptoms and Ground Reaction Forces in Runners With Patellofemoral Pain Syndrome. ( 25760965 )
2015
31
Effects of Kinesio Taping versus McConnell Taping for Patellofemoral Pain Syndrome: A Systematic Review and Meta-Analysis. ( 26185517 )
2015
32
Muscle Activation of Vastus Medialis Oblique and Vastus Lateralis in Sling-Based Exercises in Patients with Patellofemoral Pain Syndrome: A Cross-Over Study. ( 26504480 )
2015
33
Reply to Selfe (2014) letter to the editor on: Measurement properties of patient-reported outcome measures (PROMS) in patellofemoral pain syndrome: A systematic review. ( 25487345 )
2015
34
The effect of postural stabilization exercises on pain and function in females with patellofemoral pain syndrome. ( 26012938 )
2015
35
Isokinetic profile in female athletes with and without patellofemoral pain syndrome after anterior cruciate ligament reconstruction. ( 26274876 )
2015
36
WITHDRAWN: Exercise therapy for patellofemoral pain syndrome. ( 25612084 )
2015
37
Management of a patient with patellofemoral pain syndrome using neuromuscular training in decreasing medial collapse: a case report. ( 25412564 )
2015
38
Exercise for treating patellofemoral pain syndrome. ( 25603546 )
2015
39
Evaluation of a treatment algorithm for patients with patellofemoral pain syndrome: a pilot study. ( 25883866 )
2015
40
Additional Effects of an Individualized Risk Factor-Based Approach on Pain and the Function of Patients With Patellofemoral Pain Syndrome: A Randomized Controlled Trial. ( 25654629 )
2015
41
Study protocol: a randomised controlled trial comparing the long term effects of isolated hip strengthening, quadriceps-based training and free physical activity for patellofemoral pain syndrome (anterior knee pain). ( 25879452 )
2015
42
Is Hip Abduction Strength Asymmetry Present in Female Runners in the Early Stages of Patellofemoral Pain Syndrome? ( 26566993 )
2015
43
Knee orthoses for treating patellofemoral pain syndrome. ( 26645724 )
2015
44
Lower limb control and strength in runners with and without patellofemoral pain syndrome. ( 25800001 )
2015
45
The Effect of Kinesio Taping on Anterior Knee Pain Consistent With Patellofemoral Pain Syndrome: A Critically Appraised Topic. ( 25946512 )
2015
46
Intra- and Inter-session Reliability of Static and Dynamic Postural Control in Participants with and without Patellofemoral Pain Syndrome. ( 26839452 )
2015
47
Vastus medialis oblique and vastus lateralis activity during a double-leg semisquat with or without hip adduction in patients with patellofemoral pain syndrome. ( 26459411 )
2015
48
Does the Addition of Hip Strengthening to a Knee-focused Exercise Program Improve Outcomes in Patients With Patellofemoral Pain Syndrome? ( 25365356 )
2014
49
Diagnostic accuracy of the electromyography parameters associated with anterior knee pain in the diagnosis of patellofemoral pain syndrome. ( 24742937 )
2014
50
Short-term effects of patellar kinesio taping on pain and hop function in patients with patellofemoral pain syndrome. ( 24982700 )
2014

Variations for Patellofemoral Pain Syndrome

Expression for Patellofemoral Pain Syndrome

Search GEO for disease gene expression data for Patellofemoral Pain Syndrome.

Pathways for Patellofemoral Pain Syndrome

GO Terms for Patellofemoral Pain Syndrome

Cellular components related to Patellofemoral Pain Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 transcription factor AP-1 complex GO:0035976 8.62 FOS JUN

Biological processes related to Patellofemoral Pain Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 positive regulation of pri-miRNA transcription from RNA polymerase II promoter GO:1902895 9.37 FOS JUN
2 temperature homeostasis GO:0001659 9.32 EDN2 NTSR1
3 response to muscle stretch GO:0035994 9.26 FOS JUN
4 negative regulation of systemic arterial blood pressure GO:0003085 9.16 KCNK6 NTSR1
5 positive regulation of lipopolysaccharide-mediated signaling pathway GO:0031666 8.96 LY86 LY96
6 response to lipopolysaccharide GO:0032496 8.92 FOS JUN LY96 TNFRSF1A

Molecular functions related to Patellofemoral Pain Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 transcriptional activator activity, RNA polymerase II transcription factor binding GO:0001190 8.62 FOS JUN

Sources for Patellofemoral Pain Syndrome

3 CDC
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10 dbSNP
11 DGIdb
16 ExPASy
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33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
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42 MeSH
43 MESH via Orphanet
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48 NDF-RT
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52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
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70 UMLS via Orphanet
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