MCID: PTL002
MIFTS: 30

Patellofemoral Pain Syndrome

Categories: Bone diseases

Aliases & Classifications for Patellofemoral Pain Syndrome

MalaCards integrated aliases for Patellofemoral Pain Syndrome:

Name: Patellofemoral Pain Syndrome 12 41 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:14284
MeSH 41 D046788
UMLS 69 C0877149

Summaries for Patellofemoral Pain Syndrome

MalaCards based summary : Patellofemoral Pain Syndrome is related to paine syndrome and episodic pain syndrome, familial, 1, and has symptoms including metatarsalgia and arthralgia. An important gene associated with Patellofemoral Pain Syndrome is PRF1 (Perforin 1). The drugs Acetaminophen and Analgesics have been mentioned in the context of this disorder. Affiliated tissues include bone and testes.

Wikipedia : 72 Patellofemoral pain syndrome (PFPS), also known as patellar overload syndrome and runner\'s knee, is a... more...

Related Diseases for Patellofemoral Pain Syndrome

Diseases related to Patellofemoral Pain Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 paine syndrome 11.1
2 episodic pain syndrome, familial, 1 11.1
3 vascular malformation, primary intraosseous 10.0
4 patella, chondromalacia of 9.8
5 polydactyly, postaxial, with progressive myopia 9.8
6 chondromalacia 9.8
7 conjunctivitis 9.8
8 acute mountain sickness 9.8
9 ring chromosome y syndrome 9.8

Graphical network of the top 20 diseases related to Patellofemoral Pain Syndrome:



Diseases related to Patellofemoral Pain Syndrome

Symptoms & Phenotypes for Patellofemoral Pain Syndrome

UMLS symptoms related to Patellofemoral Pain Syndrome:


metatarsalgia, arthralgia

Drugs & Therapeutics for Patellofemoral Pain Syndrome

Drugs for Patellofemoral Pain Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 34)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetaminophen Approved Phase 4 103-90-2 1983
2 Analgesics Phase 4
3 Analgesics, Non-Narcotic Phase 4
4 Antipyretics Phase 4
5 Peripheral Nervous System Agents Phase 4,Phase 3
6
Lidocaine Approved, Vet_approved Phase 3 137-58-6 3676
7
Acetylcholine Approved Phase 3 51-84-3 187
8
Imidacloprid Vet_approved Phase 3 105827-78-9 86418
9 abobotulinumtoxinA Phase 3
10 Botulinum Toxins Phase 3
11 Botulinum Toxins, Type A Phase 3
12 Cholinergic Agents Phase 3
13 Neuromuscular Agents Phase 3
14 Neurotransmitter Agents Phase 3
15 onabotulinumtoxinA Phase 3
16
Hyaluronic acid Approved, Vet_approved Phase 2 9004-61-9 53477741 24759
17 Adjuvants, Immunologic Phase 2
18 Hylan Phase 2
19 Protective Agents Phase 2
20 Viscosupplements Phase 2
21
Povidone-iodine Approved 25655-41-8
22
Menthol Approved 2216-51-5 16666
23
Benzocaine Approved, Investigational 1994-09-7, 94-09-7 2337
24
Oxymetazoline Approved, Investigational 1491-59-4 4636
25
Phenylephrine Approved 59-42-7 6041
26
Ethanol Approved 64-17-5 702
27
Sulfamethazine Approved, Investigational, Vet_approved 57-68-1 5327
28
Bupivacaine Approved, Investigational 38396-39-3, 2180-92-9 2474
29 tannic acid Approved, Nutraceutical
30
s 1 (combination)
31 Antipruritics
32 Dermatologic Agents
33 Anesthetics
34 Astragalus Nutraceutical

Interventional clinical trials:

(show top 50) (show all 85)

# Name Status NCT ID Phase Drugs
1 Close Kinect Chain Exercise With Kinesio Taping in the Management of Patellofemoral Pain Syndrome Unknown status NCT02241148 Phase 4 Acetaminophen 500mg
2 Diacutaneous Fibrolysis and Patellofemoral Pain Syndrome Completed NCT02379364 Phase 3
3 A Clinical Study in the Use of Orthotics in Treating Pain in the Front of the Knee Completed NCT00118521 Phase 3
4 Comparing the Outcome of Electrical Stimulation and Physical Therapy in Patellofemoral Pain Syndrome Recruiting NCT03184545 Phase 3
5 Botox for Non-surgical Lateral Release in Patellofemoral Pain Terminated NCT00496964 Phase 3 Botulinum toxin A + exercise;Placebo
6 Comparison of The Clinical Effects Between Different Physical Therapy Tools in Patellofemoral Pain Patients Unknown status NCT00451347 Phase 1, Phase 2
7 Treatment for Patellofemoral Pain Syndrome Using Footwear Completed NCT01332110 Phase 1, Phase 2
8 Comparison of Two Protocols for Patellofemoral Pain Syndrome Completed NCT01691170 Phase 1, Phase 2
9 Assessing Foot Injuries in Infantry Recruits Wearing Different Boots Completed NCT02810002 Phase 1, Phase 2
10 Intra-articular Hyaluronic Acid Injection for Therapy-resistant Patellofemoral Pain Syndrome Recruiting NCT02613247 Phase 2
11 Comparisons of Mechanical Properties of Tendon Structures Unknown status NCT00451087 Phase 1
12 Effect of Hip Adduction Combination With Knee Extension Exercise on Morphology of Quadriceps Muscles, Pain and Functional Outcomes in Patients With PFPS Unknown status NCT00166777 Phase 1
13 Neural Mechanisms of Muscle Control in Individuals With Knee Pain Not yet recruiting NCT02854774 Phase 1
14 Foot Orthoses in Patellofemoral Pain Syndrome: a Prospective Randomized Study of Morpho-specific Versus Placebo Orthoses Unknown status NCT02250144
15 Selective Neuromuscular Electrical Stimulation on VMO Unknown status NCT02548988
16 Morphology of the VMO in Patients With PFPS and Healthy Young Adults--A Sonographic Study Unknown status NCT00173147
17 The Role of Quadriceps Contraction in Patellar Repositioning - a Computed Tomography Study Unknown status NCT00760136 Early Phase 1
18 The Effect of Muscle Strengthening Associated With Neuromuscular Stimulus in Patients With Patellofemoral Pain During Negotiating Stairs Unknown status NCT02591680
19 Prevention of Injuries by an Exercise Program – a RCT Unknown status NCT00348647
20 Randomized Evaluation of the Efficacy of Synvisc-One® for the Treatment of Patellofemoral Chondromalacia Unknown status NCT01771952
21 Evaluation of a Treatment Algorithm for Patients With Patellofemoral Pain Syndrome Completed NCT02461095
22 McConnell Patellar Taping in Static and Dynamic Postural Control of Women With Patellofemoral Pain Syndrome Completed NCT02841384
23 Comparison of Effects of Mobilization With Movement and Kinesiotaping in Patellofemoral Pain Syndrome Completed NCT02707679
24 Correlation Between the Amplitude of Ankle Dorsiflexion and Occurrence of Patellofemoral Pain Syndrome Completed NCT03213015
25 Efficiency of Patellar Taping in Treatment of Patellofemoral Pain Syndrome Completed NCT01504100
26 Comparison Study of Two Chiropractic Treatment Protocols for Knee Pain Due to Patellofemoral Pain Syndrome Completed NCT00401050
27 Dosage-dependence of Graded Exercise Therapy in Patients With Patellofemoral Pain Syndrome. Completed NCT01290705
28 Early Intervention for Adolescents With Patellofemoral Pain Syndrome Completed NCT01438762
29 Activation of Hip Muscles in Runners With Patellofemoral Syndrome Completed NCT02837289
30 The Evaluation of a Novel Treatment Algorithm for Patients With Patellofemoral Syndrome Completed NCT01767246
31 Manual Therapy and Dry Needling in Patellofemoral Syndrome Completed NCT02514005
32 Effect of Lower Back Treatment in People With Patellofemoral Pain Syndrome. Completed NCT01975311
33 Kinematics of Lower Limb, Pain and Function of the Women With Patellofemoral Pain Syndrome Completed NCT01804608
34 Effects of Lumbopelvic Manipulation on Hip and Knee Neuromuscular Activity Completed NCT01637480
35 Patellar Taping on Proprioceptive Exercises in Young Women With Patellofemoral Pain Syndrome Completed NCT02322515
36 Effectiveness Trial for Evaluating IAHA for PFPS Completed NCT01811654
37 Comparing Rehabilitation Programs for Patellofemoral Pain Syndrome Completed NCT00445224
38 Effects of Hip Abductor and External Rotator Strength Training in Patients With Patellofemoral Pain Syndrome Completed NCT00736736
39 The Effect of Kinesio Taping® on Motor Control in Patients With Patellofemoral Pain Syndrome Completed NCT03117205
40 The Effects of Dry Needling & Kinesio Tape on Anterior Knee Pain Completed NCT02118246
41 The Effects and Predictors of Patella Taping in the Treatment of Patellafemoral Pain Syndrome Completed NCT01727596
42 Investigation of Muscle Activity Pattern of Gluteus Medius and Tensor Fascia Lata in Patients With PFPS Completed NCT00451438
43 Conventional Home Exercise Programs Versus Electronic Home Exercise Versus Artificial Intelligence "Virtual Therapy" for Anterior Knee Pain Completed NCT01696162
44 Vasti Control of Patellofemoral Kinematics in Asymptomatic Volunteer Completed NCT00978003
45 Utilizing the Trunk as a Proximal Lever to Strengthen the Hip Musculature and Alter Lower Extremity Function Completed NCT03285464
46 Effects of Hip and Knee Exercises on Knee Pain in Young Adult Females With Long-standing Patellofemoral Pain Completed NCT03054701
47 The Movement Control Training Associated With Conventional Physical Therapy is More Effective Than Conventional Physical Therapy Alone in Pain and Functional Performance? Completed NCT02624245
48 Running Study for Runners With Chronic Knee Pain Completed NCT02567123
49 Rehabilitation With Patterned Electrical Neuromuscular Stimulation for Patients With Patellofemoral Pain Completed NCT02441712
50 Multidimensional Diagnostics and Effect of Activity Modification in Young Adolescents With Patellofemoral Pain Completed NCT02402673

Search NIH Clinical Center for Patellofemoral Pain Syndrome

Cochrane evidence based reviews: patellofemoral pain syndrome

Genetic Tests for Patellofemoral Pain Syndrome

Anatomical Context for Patellofemoral Pain Syndrome

MalaCards organs/tissues related to Patellofemoral Pain Syndrome:

38
Bone, Testes

Publications for Patellofemoral Pain Syndrome

Articles related to Patellofemoral Pain Syndrome:

(show top 50) (show all 346)
# Title Authors Year
1
Current clinical, radiological and treatment perspectives of patellofemoral pain syndrome. ( 29303366 )
2018
2
Effectiveness of conservative treatment for patellofemoral pain syndrome: A systematic review and meta-analysis. ( 29392329 )
2018
3
Effects of vision and cognitive load on static postural control in subjects with and without patellofemoral pain syndrome. ( 29120261 )
2018
4
Neuromuscular electrical stimulation (NMES) for patellofemoral pain syndrome. ( 29231243 )
2017
5
Effectiveness of Manual Therapy Combined With Physical Therapy in Treatment of Patellofemoral Pain Syndrome: Systematic Review. ( 28559754 )
2017
6
Squatting Re-education With Lumbo-Pelvic-Thigh Muscle Cocontraction Improves Functional Performance in Patellofemoral Pain Syndrome: A Case Presentation. ( 29133185 )
2017
7
Effects of Kinesio Taping<sup>Ar</sup>on knee function and pain in athletes with patellofemoral pain syndrome. ( 29037636 )
2017
8
Systematic Review of the Effect of Taping Techniques on Patellofemoral Pain Syndrome. ( 28617653 )
2017
9
Carryover effect of hip and knee exercises program on functional performance in individuals with patellofemoral pain syndrome. ( 28878459 )
2017
10
Comparison of ischemic compression and lumbopelvic manipulation as trigger point therapy for patellofemoral pain syndrome in young adults: A double-blind randomized clinical trial. ( 28750964 )
2017
11
Patellar bracing affects sEMG activity of leg and thigh muscles during stance phase in patellofemoral pain syndrome. ( 28697399 )
2017
12
Is there a role of pulsed electromagnetic fields in management of patellofemoral pain syndrome? Randomized controlled study at one year follow-up. ( 26756278 )
2016
13
The validity and reliability of the Thai version of the Kujala score for patients with patellofemoral pain syndrome. ( 26729626 )
2016
14
Long term effect of selective muscle strengthening in athletes with patellofemoral pain syndrome. ( 27104322 )
2016
15
TIBIOFEMORAL JOINT MOBILIZATION IN THE SUCCESSFUL MANAGEMENT OF PATELLOFEMORAL PAIN SYNDROME: A CASE REPORT. ( 27274430 )
2016
16
Core Neuromuscular Training; a Physical Activity Intervention for Individuals with Patellofemoral Pain Syndrome: 3294 Board #359 June 3, 3: 30 PM - 5: 00 PM. ( 27361863 )
2016
17
The Effect of Patellofemoral Pain Syndrome on Gait Parameters: A Literature Review. ( 27847840 )
2016
18
Effectiveness of core muscle strengthening for improving pain and dynamic balance among female patients with patellofemoral pain syndrome. ( 27313363 )
2016
19
Greek cultural adaption and validation of the Kujala anterior knee pain scale in patients with patellofemoral pain syndrome. ( 27049481 )
2016
20
Evaluating the potential synergistic benefit of a realignment brace on patients receiving exercise therapy for patellofemoral pain syndrome: a randomized clinical trial. ( 27146819 )
2016
21
Mcconnell's patellar taping does not alter knee and hip muscle activation differences during proprioceptive exercises: A randomized placebo-controlled trial in women with patellofemoral pain syndrome. ( 27693990 )
2016
22
Short-term effects of kinesio tape on joint position sense, isokinetic measurements, and clinical parameters in patellofemoral pain syndrome. ( 27512259 )
2016
23
The immediate effect of lumbopelvic manipulation on EMG of vasti and gluteus medius in athletes with patellofemoral pain syndrome: A randomized controlled trial. ( 26995778 )
2016
24
The effect of hip and knee exercises on pain, function, and strength in patientswith patellofemoral pain syndrome: a randomized controlled trial. ( 27511483 )
2016
25
Short Arc Training Effects On Knee Strength, Pain, Functional Performance With Patellofemoral Pain Syndrome Patients: 1619 Board #272 June 2, 8: 00 AM - 9: 30 AM. ( 27360538 )
2016
26
Kinematic and electromyographic analysis in patients with patellofemoral pain syndrome during single leg triple hop test. ( 27470227 )
2016
27
Comparative evaluation of ambulation patterns and isokinetic muscle strength for the application of rehabilitation exercise in patients with patellofemoral pain syndrome. ( 28174434 )
2016
28
Anterior knee pain caused by patellofemoral pain syndrome can be relieved by Botulinum toxin type A injection. ( 25683309 )
2015
29
WITHDRAWN: Exercise therapy for patellofemoral pain syndrome. ( 25612084 )
2015
30
Exercise for treating patellofemoral pain syndrome. ( 25603546 )
2015
31
Reply to Selfe (2014) letter to the editor on: Measurement properties of patient-reported outcome measures (PROMS) in patellofemoral pain syndrome: A systematic review. ( 25487345 )
2015
32
Muscle Activation of Vastus Medialis Oblique and Vastus Lateralis in Sling-Based Exercises in Patients with Patellofemoral Pain Syndrome: A Cross-Over Study. ( 26504480 )
2015
33
The effect of postural stabilization exercises on pain and function in females with patellofemoral pain syndrome. ( 26012938 )
2015
34
Predictors for identifying patients with patellofemoral pain syndrome responding to femoral nerve mobilization. ( 25576086 )
2015
35
Additional Effects of an Individualized Risk Factor-Based Approach on Pain and the Function of Patients With Patellofemoral Pain Syndrome: A Randomized Controlled Trial. ( 25654629 )
2015
36
The relationship between quadriceps strength and joint position sense, functional outcome and painful activities in patellofemoral pain syndrome. ( 25869907 )
2015
37
Effectiveness of therapeutic physical exercise in the treatment of patellofemoral pain syndrome: a systematic review. ( 26311988 )
2015
38
Exercise for treating patellofemoral pain syndrome. An abridged version of Cochrane Systematic Review. ( 26158920 )
2015
39
Intra- and Inter-session Reliability of Static and Dynamic Postural Control in Participants with and without Patellofemoral Pain Syndrome. ( 26839452 )
2015
40
The Effects of a Multimodal Rehabilitation Program on Symptoms and Ground Reaction Forces in Runners With Patellofemoral Pain Syndrome. ( 25760965 )
2015
41
Isokinetic profile in female athletes with and without patellofemoral pain syndrome after anterior cruciate ligament reconstruction. ( 26274876 )
2015
42
Effectiveness of hip muscle strengthening in patellofemoral pain syndrome patients: a systematic review. ( 26039034 )
2015
43
Lower limb control and strength in runners with and without patellofemoral pain syndrome. ( 25800001 )
2015
44
Effects of Kinesio Taping versus McConnell Taping for Patellofemoral Pain Syndrome: A Systematic Review and Meta-Analysis. ( 26185517 )
2015
45
Vastus medialis oblique and vastus lateralis activity during a double-leg semisquat with or without hip adduction in patients with patellofemoral pain syndrome. ( 26459411 )
2015
46
Study protocol: a randomised controlled trial comparing the long term effects of isolated hip strengthening, quadriceps-based training and free physical activity for patellofemoral pain syndrome (anterior knee pain). ( 25879452 )
2015
47
"Measurement properties of patient-reported outcome measures (PROMS) in patellofemoral pain syndrome: A systematic review". Green etA al. (in press corrected proof). ( 25660820 )
2015
48
The Effect of Kinesio Taping on Anterior Knee Pain Consistent With Patellofemoral Pain Syndrome: A Critically Appraised Topic. ( 25946512 )
2015
49
Clijsen R, Fuchs J, Taeymans J. Effectiveness of exercise therapy in treatment of patients with patellofemoral pain syndrome: systematic review and meta-analysis. Phys Ther. 2014;94:1697-1708. ( 26031469 )
2015
50
Evaluation of a treatment algorithm for patients with patellofemoral pain syndrome: a pilot study. ( 25883866 )
2015

Variations for Patellofemoral Pain Syndrome

Expression for Patellofemoral Pain Syndrome

Search GEO for disease gene expression data for Patellofemoral Pain Syndrome.

Pathways for Patellofemoral Pain Syndrome

GO Terms for Patellofemoral Pain Syndrome

Biological processes related to Patellofemoral Pain Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular defense response GO:0006968 8.62 LY96 PRF1

Sources for Patellofemoral Pain Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....