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PID
MCID: PLV003
MIFTS: 54

Pelvic Inflammatory Disease (PID) malady

Categories: Reproductive diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Pelvic Inflammatory Disease

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Aliases & Descriptions for Pelvic Inflammatory Disease:

Name: Pelvic Inflammatory Disease 12 52 41 3 42 14 69
Pid 12 3

Classifications:

MalaCards categories:
Anatomical: Reproductive diseases
See all MalaCards categories (disease lists)
ICD10: 33


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Summaries for Pelvic Inflammatory Disease

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MedlinePlus : 41 pelvic inflammatory disease (pid) is an infection and inflammation of the uterus, ovaries, and other female reproductive organs. it causes scarring in these organs. this can lead to infertility, ectopic pregnancy, pelvic pain, abscesses, and other serious problems. pid is the most common preventable cause of infertility in the united states. gonorrhea and chlamydia, two sexually transmitted diseases, are the most common causes of pid. other bacteria can also cause it. you are at greater risk if you are sexually active and younger than 25 have more than one sex partner douche some women have no symptoms. others have pain in the lower abdomen, fever, smelly vaginal discharge, irregular bleeding, and pain during intercourse or urination. doctors diagnose pid with a physical exam, lab tests, and imaging tests. antibiotics can cure pid. early treatment is important. waiting too long increases the risk of infertility. nih: national institute of allergy and infectious diseases

MalaCards based summary : Pelvic Inflammatory Disease, also known as pid, is related to chlamydia and fitz-hugh-curtis syndrome, and has symptoms including fever, pelvic pain and pruritus. An important gene associated with Pelvic Inflammatory Disease is CRP (C-Reactive Protein), and among its related pathways/superpathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. The drugs Bupivacaine and Triamcinolone have been mentioned in the context of this disorder. Affiliated tissues include ovary, uterus and testes, and related phenotypes are Synthetic lethal with c-Myc after tamoxifen stimulation and hematopoietic system

CDC : 3 Basic Fact Sheet | Detailed Version

Wikipedia : 71 Pelvic inflammatory disease or pelvic inflammatory disorder (PID) is an infection of the upper part of... more...

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Related Diseases for Pelvic Inflammatory Disease

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Diseases related to Pelvic Inflammatory Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 156)
id Related Disease Score Top Affiliating Genes
1 chlamydia 30.7 CD40LG HSPD1
2 fitz-hugh-curtis syndrome 11.3
3 salpingitis 11.2
4 peritonitis 11.2
5 benign multicystic peritoneal mesothelioma 10.8
6 diffuse large b-cell lymphoma 10.2 CRP MMP9
7 nguyen syndrome 10.2 TLR1 TLR2 TLR6
8 polycythemia due to hypoxia 10.2 CD40LG CRP
9 pemphigus vulgaris, familial 10.2 CD40LG CRP MMP9
10 omsk hemorrhagic fever 10.2 CD40LG MMP9 TLR4
11 epidermolysis bullosa dystrophica, ad 10.2 CRP TIRAP TLR2
12 megaloblastic anemia 10.2 CD40LG CRP TLR4
13 glycogen storage disease viii 10.2 CD40LG CRP TLR4
14 autoimmune disease of central nervous system 10.2 CRP TLR2 TLR6
15 spotted fever 10.2 CD40LG TLR2 TLR4
16 appendiceal l-cell glucagon-like peptide producing tumor 10.2 CRP TLR2 TLR4
17 pericholangitis 10.1 CRP TLR2 TLR4
18 ovarian cystic teratoma 10.1 CD40LG TLR2 TLR4
19 dentin caries 10.1 CD40LG TLR2 TLR4
20 optic nerve neoplasm 10.1 CCL2 CRP MMP9
21 leiomyosarcoma 10.1 CD40LG CRP HSPD1
22 ovarian serous cystadenocarcinoma 10.1 CD40LG CRP HSPD1
23 endobronchial leiomyoma 10.1 CD40LG CHI3L1 CRP
24 cervicitis 10.1
25 plummer's disease 10.1 CD40LG CRP IFNG
26 cannabis dependence 10.1 CD40LG CRP
27 pseudoainhum 10.1 TLR2 TLR4
28 basilar artery occlusion 10.1 CD40LG HSPD1 TLR6
29 nephropathy with pretibial epidermolysis bullosa and deafness 10.1 CD40LG TLR2 TLR4
30 infertility 10.1
31 premature menopause 10.1 CRP HSPD1 TLR2
32 choroiditis 10.1 CCL2 CRP TLR4
33 whipple disease 10.1 CCL2 TLR4 TLR6
34 paralytic poliomyelitis 10.1 IFNG TLR4
35 disease of mental health 10.1 CD40LG IFNG TLR2
36 calcinosis 10.1 CCL2 CD40LG CRP
37 unilateral hypoactive labyrinth 10.1 CRP MMP9 TLR2 TLR4
38 respiratory system disease 10.1 CD40LG CRP IFNG
39 neovascular glaucoma 10.1 CCL2 CRP TLR4
40 hypertensive heart disease 10.1 CD40LG CRP TLR2 TLR4
41 urethral intrinsic sphincter deficiency 10.1 CCL2 IFNG MMP9
42 rift valley fever 10.1 CRP IFNG TLR4
43 rickettsia parkeri spotted fever 10.1 HSPD1 IFNG
44 acute female pelvic peritonitis 10.1
45 asbestosis 10.1 CRP HSPD1 TLR2
46 testicular lymphoma 10.1 CD40LG CRP IFNG
47 parasitic ichthyosporea infectious disease 10.1 TLR1 TLR2 TLR4 TLR6
48 ectopic pregnancy 10.1
49 polyarteritis nodosa 10.1 IFNG TLR2 TLR4
50 eating disorder 10.1 CCL2 CD40LG CRP

Comorbidity relations with Pelvic Inflammatory Disease via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Pelvic Inflammatory Disease:



Diseases related to Pelvic Inflammatory Disease
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Symptoms & Phenotypes for Pelvic Inflammatory Disease

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UMLS symptoms related to Pelvic Inflammatory Disease:


fever, pelvic pain, pruritus

GenomeRNAi Phenotypes related to Pelvic Inflammatory Disease according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with c-Myc after tamoxifen stimulation GR00215-A 8.92 CRP CTSA IFNG TLR6

MGI Mouse Phenotypes related to Pelvic Inflammatory Disease:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10 CD40LG CHI3L1 CTSA HLA-DQA1 IFNG MMP9
2 immune system MP:0005387 9.97 HLA-DQA1 IFNG MMP9 TIRAP TLR1 TLR2
3 cardiovascular system MP:0005385 9.92 CD40LG CRP CTSA IFNG MMP9 TIRAP
4 renal/urinary system MP:0005367 9.43 IFNG MMP9 TLR2 TLR4 CD40LG CTSA
5 reproductive system MP:0005389 9.17 CD40LG CTSA HSPD1 IFNG MMP9 TLR4
Sources

Drugs & Therapeutics for Pelvic Inflammatory Disease

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Drugs for Pelvic Inflammatory Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 338)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bupivacaine Approved, Investigational Phase 4,Phase 1,Phase 2 2180-92-9, 38396-39-3 2474
2
Triamcinolone Approved, Vet_approved Phase 4,Phase 2 124-94-7 31307
3
Acetaminophen Approved Phase 4 103-90-2 1983
4
Ibuprofen Approved Phase 4 15687-27-1 3672
5
Clindamycin Approved, Vet_approved Phase 4 18323-44-9 29029
6
Levofloxacin Approved, Investigational Phase 4,Phase 3 100986-85-4 149096
7
Metronidazole Approved Phase 4,Phase 3,Phase 2 443-48-1 4173
8
Ofloxacin Approved Phase 4,Phase 3 82419-36-1 4583
9
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3 50-28-2 5757 53477783
10
Ethinyl Estradiol Approved Phase 4,Phase 3 57-63-6 5991
11
Moxifloxacin Approved, Investigational Phase 4,Phase 3 354812-41-2, 151096-09-2 152946
12
Norgestimate Approved Phase 4,Phase 3 35189-28-7 6540478
13
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 2 564-25-0 54671203
14
Povidone-iodine Approved Phase 4,Phase 3 25655-41-8
15
Ethanol Approved Phase 4,Phase 2 64-17-5 702
16
Hydrocortisone Approved, Vet_approved Phase 4,Phase 2 50-23-7 5754 657311
17
Mannitol Approved, Investigational Phase 4 69-65-8 453 6251
18
Levonorgestrel Approved, Investigational Phase 4 797-63-7, 17489-40-6 13109
19
Ketorolac Approved Phase 4,Phase 3 74103-06-3, 66635-83-4 3826
20
Azithromycin Approved Phase 4,Phase 3 83905-01-5 55185 53477736 447043
21
Cefazolin Approved Phase 4 25953-19-9 656510 33255
22
Copper Approved Phase 4 15158-11-9, 7440-50-8 27099
23
Hydrocodone Approved, Illicit Phase 4 125-29-1 5284569
24
Hydromorphone Approved, Illicit Phase 4 466-99-9 5284570
25
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
26
Butyric Acid Experimental Phase 4,Phase 2 107-92-6 264
27
Resveratrol Experimental, Investigational Phase 4 501-36-0, 955365-80-7 24856436 445154
28 Anesthetics Phase 4,Phase 2,Phase 1
29 Anesthetics, Local Phase 4,Phase 2,Phase 1
30 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1
31 Central Nervous System Depressants Phase 4,Phase 2,Phase 1
32 glucocorticoids Phase 4,Phase 3,Phase 2,Phase 1
33 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
34 Hormones Phase 4,Phase 3,Phase 2,Phase 1
35 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
36 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Phase 1
37 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
38 triamcinolone acetonide Phase 4,Phase 2
39 Triamcinolone diacetate Phase 4,Phase 2
40 Triamcinolone hexacetonide Phase 4,Phase 2
41 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1
42 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
43 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2
44 Antitubercular Agents Phase 4,Phase 2,Phase 3
45 Contraceptive Agents Phase 4,Phase 3
46 Contraceptives, Oral Phase 4,Phase 3
47 Contraceptives, Oral, Combined Phase 4,Phase 3
48 Micronutrients Phase 4,Phase 3,Phase 2
49 Trace Elements Phase 4,Phase 3,Phase 2
50 Analgesics Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 189)
id Name Status NCT ID Phase
1 Comparative Study of Mesh Versus No Mesh in Prolapse Surgery Unknown status NCT00153257 Phase 4
2 Trigger Point Injections and Pelvic Rehabilitation for the Treatment of Pelvic Floor Myalgia and Sexual Pain Unknown status NCT02022722 Phase 4
3 Investigation of Sacroiliac Fusion Treatment (INSITE) Unknown status NCT01681004 Phase 4
4 To Compare Ofloxacin With Azitromycin for Pelvic Inflammatory Disease (PID) Treatment Completed NCT01241110 Phase 4
5 Moxifloxacin Versus Ofloxacin Plus Metronidazole in Uncomplicated Pelvic Inflammatory Disease: Multicenter Randomized Controlled Trials Completed NCT01799356 Phase 4
6 Doxycycline Prophylaxis at Vacuum Aspiration Trial Completed NCT00547170 Phase 4
7 Does Preoperative Vaginal Preparation With Povidone-iodine Before Cesarean Delivery Reduce the Risk of Endometritis? Completed NCT01437228 Phase 4
8 Homeopathic Treatment of Chronic Pelvic Pain in Women With Endometriosis Completed NCT02427386 Phase 4
9 Prevention of Acute Radiation Enteritis With Glutamine Completed NCT00828399 Phase 4
10 Comparative Study Between Hydrocortisone and Mannitol in Treatment of Postdural Puncture Headache Completed NCT02760862 Phase 4
11 NITI CAR27 (ColonRing) Compression Anastomosis in Colorectal Surgery Completed NCT01056913 Phase 4
12 Resveratrol for Pain Due to Endometriosis Completed NCT02475564 Phase 4
13 Surgical Success After Laparoscopic vs Abdominal Hysterectomy Recruiting NCT01793584 Phase 4
14 Preoperative Vaginal Cleansing With Povidone Iodine and the Risk of Post Cesarean Endometritis Recruiting NCT02693483 Phase 4
15 Comparison of VoLumen and Breeza Oral Contrast Agents in Pediatric Patients Recruiting NCT02946203 Phase 4
16 Ice T Postoperative Multimodal Pain Regimen in FPMRS Surgery Active, not recruiting NCT03052816 Phase 4
17 Comparison Between Intrauterine Contraceptive Device Insertion During Cesarean Section Vs Conventional Application Enrolling by invitation NCT02674139 Phase 4
18 Treatment Utility of Postpartum Antibiotics in Chorioamnionitis Terminated NCT01585129 Phase 4
19 Efficacy of Gralise® for Chronic Pelvic Pain Terminated NCT01678911 Phase 4
20 Comparison Study of Cefazolin Versus Cefazolin Plus Azithromycin Prophylaxis in Post-Cesarean Endometritis Withdrawn NCT01721616 Phase 4
21 Infliximab Therapy in Patients With Refractory Polymyalgia Rheumatica Unknown status NCT01423591 Phase 3
22 A Trial Comparing Moxifloxacin Versus Levofloxacin Plus Metronidazole In Uncomplicated Pelvic Inflammatory Disease Completed NCT00453349 Phase 3
23 Uncomplicated Pelvic Inflammatory Disease. Treatment With Moxifloxacin. Completed NCT00683865 Phase 3
24 Study Of Azithromycin Intravenous Formulation Against Pelvic Inflammatory Disease (PID) In Japan Completed NCT00871494 Phase 3
25 A Phase 3 Study Of Intravenous Metronidazole For Intrabdominal Infection Completed NCT01473836 Phase 3
26 Home Screening for Chlamydia Surveillance Completed NCT00177437 Phase 3
27 Vasopressin Versus Epinephrine in Myomectomy Completed NCT01861015 Phase 3
28 Antibiotic Prophylaxis in Prelabor Rupture of Membranes at Term Completed NCT01633294 Phase 2, Phase 3
29 Efficacy Study of a Standardized Pollen Extract Preparation (Cernilton) to Treat Inflammatory Chronic Prostatitis-Chronic Pelvic Pain Syndrome (CP-CPPS) Completed NCT00919893 Phase 3
30 Clinical Approaches to Ileal Pouch Dysfunction Completed NCT00293553 Phase 3
31 The Effects of Local Vaginal Estrogen in Postmenopausal Women With Pelvic Organ Prolapse Completed NCT00803335 Phase 3
32 Efficacy Study of Adalimumab to Treat Interstitial Cystitis Completed NCT01295814 Phase 3
33 Effects of Preoperative Dexamethasone Study on QOL After Vaginal Reconstructive Surgery for POP Completed NCT02073734 Phase 3
34 Treximet (Sumatriptan/Naproxen Sodium), Formerly Known as TREXIMA, for Menstrual Migraine in Women With Dysmenorrhea Completed NCT00329459 Phase 3
35 Menstrual Migraine Treatment With TREXIMET (Formerly Known as TREXIMA) Completed NCT00329355 Phase 3
36 Efficacy and Safety of IV Diclofenac (DIC075V) for Pain After Abdominal or Pelvic Surgery Completed NCT00448110 Phase 3
37 Chlorhexidine Gluconate vs Povidone-Iodine Vaginal Cleansing Solution Prior to Cesarean Delivery Recruiting NCT02915289 Phase 3
38 Botulinum Toxin A (Botox) in Tissue Expander Breast Reconstruction Recruiting NCT01591746 Phase 3
39 Radiation Induced Cystitis Treated With Hyperbaric Oxygen - A Randomized Controlled Trial Recruiting NCT01659723 Phase 2, Phase 3
40 Clobetasol Proprionate Versus Fractionated CO2 Laser for the Treatment of Lichen Sclerosus Recruiting NCT02573883 Phase 3
41 Cyclophosphamide for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Recruiting NCT02460588 Phase 3
42 Treatment of Heavy and/or Prolonged Menstrual Bleeding Without Organic Cause Not yet recruiting NCT02943655 Phase 3
43 Bulking Agent Versus Electrostimulation Therapy in Anal Incontinence Not yet recruiting NCT03052946 Phase 2, Phase 3
44 Empiric Therapy of Mucopurulent Cervicitis (MPC) Terminated NCT01072136 Phase 3
45 A Randomized Multicenter Double-Blind CT to Evaluate the Efficacy and Safety of Mycophenolate Mofetil . . . Terminated NCT00451867 Phase 3
46 Effectiveness of Silodosin in Medical Expulsive Therapy for Ureteral Pelvic Stone From 4 to 10 mm. Terminated NCT02090439 Phase 3
47 Enbrel-Sulfasalazin-Early-Axial Spondyloarthritis (AS) Unknown status NCT00844142 Phase 2
48 The Importance of Anti-anaerobic Therapy for Acute Pelvic Inflammatory Disease (PID) Completed NCT01160640 Phase 2
49 An Investigational Agent for the Treatment of Complicated Intra-Abdominal Infections or Acute Pelvic Infections (0826-038) Completed NCT00092170 Phase 2
50 Use of Essure® Micro-inserts in Women With Hydrosalpinx Prior to In Vitro Fertilization: A Prospective, Multicenter, International Feasibility Study Completed NCT01221974 Phase 1, Phase 2

Search NIH Clinical Center for Pelvic Inflammatory Disease

Cochrane evidence based reviews: pelvic inflammatory disease

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Genetic Tests for Pelvic Inflammatory Disease

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Anatomical Context for Pelvic Inflammatory Disease

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MalaCards organs/tissues related to Pelvic Inflammatory Disease:

39
Ovary, Uterus, Testes, Neutrophil, Breast, T Cells, Skin
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Publications for Pelvic Inflammatory Disease

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Articles related to Pelvic Inflammatory Disease:

(show top 50) (show all 591)
id Title Authors Year
1
Pelvic inflammatory disease and salpingitis: incidence of primary and repeat episodes in England. ( 27678278 )
2017
2
Clinical characteristics of genital chlamydia infection in pelvic inflammatory disease. ( 28086838 )
2017
3
Pelvic Inflammatory Disease and the Risk of Ovarian Cancer and Borderline Ovarian Tumors: A Pooled Analysis of 13 Case-Control Studies. ( 27941069 )
2017
4
Whole-Exome Sequencing to Identify Novel Biological Pathways Associated With Infertility After Pelvic Inflammatory Disease. ( 27898568 )
2017
5
Is Pelvic Inflammatory Disease a Risk Factor for Ovarian Cancer? ( 27672055 )
2017
6
Characteristics of pelvic inflammatory disease where no sexually transmitted infection is identified: a cross-sectional analysis of routinely collected sexual health clinic data. ( 27091727 )
2016
7
Pelvic inflammatory disease: improving awareness, prevention, and treatment. ( 27578991 )
2016
8
Reproductive outcomes of patients being hospitalised with pelvic inflammatory disease. ( 27750467 )
2016
9
Population attributable fraction of pelvic inflammatory disease associated with chlamydia and gonorrhoea: a cross-sectional analysis of Australian sexual health clinic data. ( 27091729 )
2016
10
Care-Seeking Behavior After Notification Among Young Women With Recurrent Sexually Transmitted Infections After Pelvic Inflammatory Disease. ( 27507807 )
2016
11
MDCT of pelvic inflammatory disease: a review of the pathophysiology, gamut of imaging findings, and treatment. ( 27646971 )
2016
12
Disseminated histoplasmosis presenting as pelvic inflammatory disease. ( 26783441 )
2016
13
Risk of uterine, ovarian and breast cancer following pelvic inflammatory disease: a nationwide population-based retrospective cohort study. ( 27809870 )
2016
14
Assessing Trends in Chlamydia Positivity and Gonorrhea Incidence and Their Associations With the Incidence of Pelvic Inflammatory Disease and Ectopic Pregnancy in Washington State, 1988-2010. ( 26656441 )
2016
15
Association Between Reduced Risk of Intracerebral Hemorrhage and Pelvic Inflammatory Disease. ( 26844517 )
2016
16
Identification of novel microbes associated with pelvic inflammatory disease and infertility. ( 26825087 )
2016
17
Increased risk of borderline ovarian tumors in women with a history of pelvic inflammatory disease: A nationwide population-based cohort study. ( 27549433 )
2016
18
Risk of psychiatric disorders following pelvic inflammatory disease: a nationwide population-based retrospective cohort study. ( 26821967 )
2016
19
Gas chromatography-mass spectrometric method-based urine metabolomic profile of rats with pelvic inflammatory disease. ( 27168785 )
2016
20
Proportion of Pelvic Inflammatory Disease Cases Caused by Chlamydia trachomatis: Consistent Picture From Different Methods. ( 27260786 )
2016
21
The anti-inflammatory effect of Andrographis paniculata (Burm. f.) Nees on pelvic inflammatory disease in rats through down-regulation of the NF-I_B pathway. ( 27887650 )
2016
22
Improving Adolescent Pelvic Inflammatory Disease Follow-up From the Emergency Department: Randomized Controlled Trial With Text Messages. ( 26686262 )
2016
23
Pelvic inflammatory disease increases the risk of a second primary malignancy in patients with cervical cancer treated by surgery alone. ( 27893679 )
2016
24
Group A streptococcal toxic shock syndrome secondary to necrotizing pelvic inflammatory disease in a postmenopausal woman. ( 27419069 )
2016
25
Pelvic Inflammatory Disease: Diagnosis And Treatment In The Emergency Department. ( 27879197 )
2016
26
Recruitment of Minority Adolescents and Young Adults into Randomised Clinical Trials: Testing the Design of the Technology Enhanced Community Health Nursing (TECH-N) Pelvic Inflammatory Disease Trial. ( 27617108 )
2016
27
Invited Commentary on "Pelvic Inflammatory Disease," with Response from Dr Revzin and Colleagues. ( 27618332 )
2016
28
Fitz-Hugh-Curtis syndrome lacking typical characteristics of pelvic inflammatory disease. ( 27335367 )
2016
29
MRI in pelvic inflammatory disease: a pictorial review. ( 27933478 )
2016
30
Usefulness of Serum Procalcitonin Levels in Predicting Tubo-Ovarian Abscess in Patients with Acute Pelvic Inflammatory Disease. ( 27592364 )
2016
31
Pelvic inflammatory disease. ( 27107781 )
2016
32
Updated French guidelines for diagnosis and management of pelvic inflammatory disease. ( 27170602 )
2016
33
Pelvic Inflammatory Disease: Multimodality Imaging Approach with Clinical-Pathologic Correlation. ( 27618331 )
2016
34
Sample size considerations using mathematical models: an example with Chlamydia trachomatis infection and its sequelae pelvic inflammatory disease. ( 26084755 )
2015
35
The reproductive cycle is a pathogenic determinant during gonococcal pelvic inflammatory disease in mice. ( 26693700 )
2015
36
Risk of Endometrial Cancer in Women With Pelvic Inflammatory Disease: A Nationwide Population-Based Retrospective Cohort Study. ( 26313769 )
2015
37
Pelvic Inflammatory Disease in Virgin Women with Tubo-ovarian Abscess: A Single-center Experience and Literature Review. ( 26260586 )
2015
38
Physician Survey Assessing Pelvic Inflammatory Disease Knowledge and Attitudes to Identify Diagnosing and Reporting Barriers. ( 26341567 )
2015
39
Pelvic inflammatory disease. ( 25992748 )
2015
40
Smoking, poor nutrition, and sexually transmitted infections associated with pelvic inflammatory disease in remote North Queensland Indigenous communities, 1998-2005. ( 25887145 )
2015
41
Management of Pelvic Inflammatory Disease in Selected U.S. Sexually Transmitted Disease Clinics: Sexually Transmitted Disease Surveillance Network, January 2010-December 2011. ( 26165434 )
2015
42
Establishment of HCl-LPS-induced pelvic inflammatory disease model. ( 26726020 )
2015
43
RNA Biosignatures in Adolescent Patients in a Pediatric Emergency Department With Pelvic Inflammatory Disease. ( 26125533 )
2015
44
Correlation Between Bladder Pain Syndrome/Interstitial Cystitis and Pelvic Inflammatory Disease. ( 26579800 )
2015
45
Understanding pelvic inflammatory disease. ( 25585227 )
2015
46
Enterobius Vermicularis-Associated Pelvic Inflammatory Disease in a Child. ( 26485322 )
2015
47
Pelvic inflammatory disease in the adolescent: a poignant, perplexing, potentially preventable problem for patients and physicians. ( 25514575 )
2015
48
Pelvic Inflammatory Disease. ( 26267641 )
2015
49
Does the Degree of Perihepatitis Have Any Relevance to the Severity of the Manifestations of Pelvic Inflammatory Disease on Multidetector Computed Tomography? ( 26248151 )
2015
50
A review of antibiotic therapy for pelvic inflammatory disease. ( 26126798 )
2015
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Variations for Pelvic Inflammatory Disease

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Expression for Pelvic Inflammatory Disease

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Search GEO for disease gene expression data for Pelvic Inflammatory Disease.
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Pathways for Pelvic Inflammatory Disease

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Pathways related to Pelvic Inflammatory Disease according to GeneCards Suite gene sharing:

(show all 36)
id Super pathways Score Top Affiliating Genes
1
Innate Immune System 62
Show member pathways
 13.81 CCL2 CD40LG CHI3L1 CRP CTSA HLA-DQA1
2
Class I MHC mediated antigen processing and presentation 62
Show member pathways
 13.37 CD40LG CTSA HLA-DQA1 TIRAP TLR1 TLR2
3
Akt Signaling 60
Show member pathways
 13.32 CCL2 CD40LG TIRAP TLR1 TLR2 TLR4
4
IL-2 Pathway 60
Show member pathways
 13.12 HLA-DQA1 IFNG TLR1 TLR2 TLR4 TLR6
5
Toll-Like receptor Signaling Pathways 61
Show member pathways
 12.93 CCL2 TIRAP TLR1 TLR2 TLR4 TLR6
6
Toll-like Receptor Signaling Pathway 37 1
Show member pathways
 12.75 CCL2 IFNG MMP9 TIRAP TLR1 TLR2
7
Influenza A 37
Show member pathways
 12.74 CCL2 HLA-DQA1 IFNG TLR2 TLR4
8
NF-KappaB Family Pathway 60
Show member pathways
 12.64 CD40LG TLR1 TLR2 TLR4 TLR6
9
TRAF Pathway 60
Show member pathways
 12.57 CD40LG TIRAP TLR1 TLR2 TLR4 TLR6
10
Th17 cell differentiation 37
Show member pathways
 12.5 HLA-DQA1 IFNG TLR2 TLR4
11
NF-kappaB Signaling 4
12.5 CCL2 CD40LG IFNG TLR1 TLR2 TLR6
12
Antigen processing-Cross presentation 62
Show member pathways
 12.43 TIRAP TLR1 TLR2 TLR4 TLR6
13
IL-17 Family Signaling Pathways 61
Show member pathways
 12.27 CCL2 IFNG MMP9 TLR2
14
Diseases associated with the TLR signaling cascade 62
Show member pathways
 12.23 TIRAP TLR1 TLR2 TLR4 TLR6
15
Toxoplasmosis 37
Show member pathways
 12.22 CD40LG HLA-DQA1 IFNG TLR2 TLR4
16
Phagosome 37
12.1 HLA-DQA1 TLR2 TLR4 TLR6
17
p53 Pathway (RnD) 61
12.04 CCL2 TLR1 TLR2 TLR4 TLR6
18
Bacterial infections in CF airways 21
Show member pathways
 12.02 IFNG TIRAP TLR1 TLR2 TLR4 TLR6
19
MAPK Pathway 68
Show member pathways
 12 TLR1 TLR2 TLR4 TLR6
20
Fluid shear stress and atherosclerosis 37
11.99 CCL2 IFNG MMP9
21
Spinal Cord Injury 1
11.98 CCL2 IFNG MMP9 TLR4
22
Colorectal Cancer Metastasis 60
11.95 IFNG MMP9 TLR1 TLR2 TLR4 TLR6
23
IL27-mediated signaling events 1
Show member pathways
 11.9 IFNG TLR1 TLR2 TLR4 TLR6
24
Th17 Differentiation Pathway 61
Show member pathways
 11.86 IFNG TLR1 TLR2 TLR4 TLR6
25
Amoebiasis 37
11.82 IFNG TLR2 TLR4
26
NF-kappa B signaling pathway 37
11.81 CD40LG TIRAP TLR4
27
Phagocytosis of Microbes 60
11.81 TLR1 TLR2 TLR4 TLR6
28
Rheumatoid arthritis 37
11.79 CCL2 HLA-DQA1 IFNG TLR2 TLR4
29
IgA-Producing B Cells in the Intestine 61
11.67 CD40LG TLR2 TLR4
30
Photodynamic therapy-induced NF-kB survival signaling 1
Show member pathways
 11.62 CD40LG IFNG MMP9
31
Legionellosis 37
11.54 HSPD1 TLR2 TLR4
32
MSP-RON Signaling 60
11.52 CCL2 IFNG TLR2 TLR4
33
Tuberculosis 37
11.48 HLA-DQA1 HSPD1 IFNG TIRAP TLR1 TLR2
34
A-beta Pathways: Uptake and Degradation 61
11.34 CCL2 CD40LG MMP9 TLR4
35
Malaria 37
11.24 CCL2 CD40LG IFNG TLR2 TLR4
36
IL1 and megakaryocytes in obesity 1
10.75 CCL2 IFNG MMP9 TLR1 TLR2
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GO Terms for Pelvic Inflammatory Disease

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Cellular components related to Pelvic Inflammatory Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 integral component of plasma membrane GO:0005887 9.85 CD40LG HLA-DQA1 TLR1 TLR2 TLR4 TLR6
2 extracellular space GO:0005615 9.8 CCL2 CD40LG CHI3L1 CRP HSPD1 IFNG
3 phagocytic vesicle membrane GO:0030670 9.5 TLR1 TLR2 TLR6
4 membrane raft GO:0045121 9.46 HSPD1 TLR1 TLR2 TLR6
5 lipopolysaccharide receptor complex GO:0046696 8.96 HSPD1 TLR4
6 Toll-like receptor 1-Toll-like receptor 2 protein complex GO:0035354 8.62 TLR1 TLR2

Biological processes related to Pelvic Inflammatory Disease according to GeneCards Suite gene sharing:

(show all 50)
id Name GO ID Score Top Affiliating Genes
1 defense response to bacterium GO:0042742 9.96 IFNG TLR1 TLR4 TLR6
2 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.94 CCL2 CHI3L1 TIRAP TLR4
3 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.89 CD40LG TIRAP TLR2 TLR4
4 response to lipopolysaccharide GO:0032496 9.89 CCL2 HSPD1 TIRAP TLR2 TLR4
5 cellular response to lipopolysaccharide GO:0071222 9.88 CCL2 IFNG TLR4
6 defense response to Gram-positive bacterium GO:0050830 9.84 CRP TIRAP TLR2
7 positive regulation of inflammatory response GO:0050729 9.83 HSPD1 TLR2 TLR4
8 inflammatory response GO:0006954 9.81 CCL2 CD40LG CHI3L1 CRP TIRAP TLR1
9 positive regulation of interleukin-6 production GO:0032755 9.8 HSPD1 TLR2 TLR4
10 positive regulation of tumor necrosis factor production GO:0032760 9.77 CCL2 IFNG TIRAP TLR2 TLR4
11 lipopolysaccharide-mediated signaling pathway GO:0031663 9.76 CCL2 TLR2 TLR4
12 toll-like receptor signaling pathway GO:0002224 9.76 TLR1 TLR2 TLR4 TLR6
13 positive regulation of interleukin-10 production GO:0032733 9.73 CD40LG HSPD1 TLR2 TLR4
14 positive regulation of interleukin-8 production GO:0032757 9.72 TIRAP TLR2 TLR4
15 positive regulation of NF-kappaB import into nucleus GO:0042346 9.71 TLR2 TLR4
16 activation of NF-kappaB-inducing kinase activity GO:0007250 9.71 CHI3L1 TIRAP TLR6
17 positive regulation of chemokine production GO:0032722 9.7 TLR2 TLR4
18 toll-like receptor 4 signaling pathway GO:0034142 9.7 TIRAP TLR4
19 negative regulation of growth of symbiont in host GO:0044130 9.7 IFNG TIRAP
20 cell activation GO:0001775 9.7 TLR1 TLR2 TLR6
21 microglial cell activation GO:0001774 9.69 TLR2 TLR6
22 I-kappaB phosphorylation GO:0007252 9.69 TLR2 TLR4
23 T-helper 1 type immune response GO:0042088 9.69 TLR4 TLR6
24 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.69 CCL2 TLR2 TLR4
25 negative regulation of interleukin-17 production GO:0032700 9.68 IFNG TLR4
26 positive regulation of interferon-alpha production GO:0032727 9.68 HSPD1 TLR4
27 positive regulation of tumor necrosis factor biosynthetic process GO:0042535 9.68 TLR1 TLR4
28 macrophage activation GO:0042116 9.68 TLR1 TLR4
29 interleukin-1 beta secretion GO:0050702 9.67 TLR4 TLR6
30 positive regulation of MHC class II biosynthetic process GO:0045348 9.67 IFNG TLR4
31 positive regulation of interleukin-12 biosynthetic process GO:0045084 9.65 IFNG TLR4
32 cellular response to lipoteichoic acid GO:0071223 9.65 TIRAP TLR2 TLR4
33 positive regulation of NLRP3 inflammasome complex assembly GO:1900227 9.64 TLR4 TLR6
34 cellular response to diacyl bacterial lipopeptide GO:0071726 9.63 TLR2 TLR6
35 toll-like receptor TLR6:TLR2 signaling pathway GO:0038124 9.63 TLR2 TLR6
36 cellular response to triacyl bacterial lipopeptide GO:0071727 9.62 TLR1 TLR2
37 regulation of cytokine secretion GO:0050707 9.62 TLR1 TLR2 TLR4 TLR6
38 cellular response to bacterial lipopeptide GO:0071221 9.61 TIRAP TLR2
39 nitric oxide metabolic process GO:0046209 9.61 TLR2 TLR6
40 toll-like receptor TLR1:TLR2 signaling pathway GO:0038123 9.6 TLR1 TLR2
41 detection of diacyl bacterial lipopeptide GO:0042496 9.58 TLR2 TLR6
42 detection of triacyl bacterial lipopeptide GO:0042495 9.57 TLR1 TLR2
43 response to bacterial lipoprotein GO:0032493 9.56 TLR2 TLR6
44 positive regulation of interleukin-6 biosynthetic process GO:0045410 9.56 IFNG TIRAP TLR1 TLR6
45 MyD88-dependent toll-like receptor signaling pathway GO:0002755 9.43 HSPD1 TIRAP TLR1 TLR2 TLR4 TLR6
46 positive regulation of interleukin-12 production GO:0032735 9.1 CD40LG HSPD1 IFNG TIRAP TLR2 TLR4
47 innate immune response GO:0045087 10.06 TIRAP TLR1 TLR2 TLR4 TLR6
48 immune system process GO:0002376 10.04 HLA-DQA1 TLR1 TLR2 TLR4 TLR6
49 immune response GO:0006955 10.01 CCL2 CD40LG HLA-DQA1 IFNG TLR1 TLR2
50 positive regulation of gene expression GO:0010628 10 CRP IFNG TLR2 TLR4

Molecular functions related to Pelvic Inflammatory Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 transmembrane signaling receptor activity GO:0004888 9.67 TLR1 TLR2 TLR4 TLR6
2 receptor activity GO:0004872 9.62 TLR1 TLR2 TLR4 TLR6
3 lipopolysaccharide binding GO:0001530 9.33 HSPD1 TLR2 TLR4
4 lipopolysaccharide receptor activity GO:0001875 9.26 TLR2 TLR4
5 lipopeptide binding GO:0071723 9.13 TLR1 TLR2 TLR6
6 Toll-like receptor 2 binding GO:0035663 8.8 TIRAP TLR1 TLR6
Sources

Sources for Pelvic Inflammatory Disease

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
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36 IUPHAR
37 KEGG
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70 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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