Pelvic Inflammatory Disease: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical Trials

Summaries for Pelvic Inflammatory Disease

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³³MedlinePlus, ³CDC, ⁶³Wikipedia, ³²MalaCards
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MedlinePlus:³³ Pelvic inflammatory disease (pid) is an infection and inflammation of the uterus, ovaries, and other female reproductive organs. it causes scarring in these organs. this can lead to infertility, ectopic pregnancy, pelvic pain, abscesses, and other serious problems. pid is the most common preventable cause of infertility in the united states. gonorrhea and chlamydia, two sexually transmitted diseases, are the most common causes of pid. other bacteria can also cause it. you are at greater risk if you are sexually active and younger than 25 have more than one sex partner douche some women have no symptoms. others have pain in the lower abdomen, fever, smelly vaginal discharge, irregular bleeding, and pain during intercourse or urination. doctors diagnose pid with a physical exam, lab tests, and imaging tests. antibiotics can cure pid. early treatment is important. waiting too long increases the risk of infertility. nih: national institute of allergy and infectious diseases

MalaCards: Pelvic Inflammatory Disease, also known as inflammatory disease of female pelvic organs and/or tissues, is related to cervicitis and endometriosis. An important gene associated with Pelvic Inflammatory Disease is HSPD1 (heat shock 60kDa protein 1 (chaperonin)), and among its related pathways are MHC class II antigen presentation and Immune response Bacterial infections in normal airways. The compounds cycloheximide and ninhydrin have been mentioned in the context of this disorder. Affiliated tissues include ovary, uterus and testes, and related mouse phenotypes are hematopoietic system and renal/urinary system.

CDC:³ Basic Fact Sheet | Detailed Version

Wikipedia:⁶³ Pelvic inflammatory disease (or disorder) (PID) is a term for inflammation of the uterus, fallopian... more...

Aliases & Classifications for Pelvic Inflammatory Disease

Sources:
⁸Disease Ontology, ¹⁰DISEASES, ⁴⁴Novoseek, ³³MedlinePlus, ⁶⁰UMLS, ⁵⁶SNOMED-CT, ²⁷ICD9CM, ³⁴MeSH, ³⁹NCIt, ²⁵ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Reproductive diseases

ICD10: ²⁵

Diseases of the genitourinary system

Inflammatory diseases of female pelvic organs

Female pelvic inflammatory disorders in diseases classified elsewhere

Female pelvic inflammatory disorders in other diseases classified elsewhere

Other female pelvic inflammatory diseases

Other specified female pelvic inflammatory diseases

Aliases & Descriptions:

pelvic inflammatory disease ⁸ ¹⁰ ⁴⁴ ³³ ⁶⁰

inflammatory disease of female pelvic organs and/or tissues ⁸

female pelvic inflammatory disease ⁸

pid ⁸

External Ids:

Disease Ontology⁸ DOID:1003

ICD9CM²⁷ 614.9, 614-616.99

MeSH³⁴ D000292

SNOMED-CT⁵⁶ 266651008, 198244005, 198178006 155974004, 155967009, 198570007, 198130006, 266648001, 198131005, 37518008, 266584000, 155986001, 155968004, more

NCIt³⁹ C3889

ICD10²⁵ N74, N73.8, N74.8

UMLS⁶⁰ C0242172

Related Diseases for Pelvic Inflammatory Disease

Sources:
¹⁷GeneCards, ¹⁸GeneDecks
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Diseases related to Pelvic Inflammatory Disease via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50) (show all 132)

id	Related Disease	Score	Top Affiliating Genes
1	cervicitis	30.9	HSPD1
2	endometriosis	30.7	PLAU
3	peritonitis	30.6	LACTB
4	salpingitis	30.6	HSPD1
5	inflammatory bowel disease	30.6	CHI3L1, GUSB, HSPD1, TLR4, LCN2
6	ovarian cancer	30.6	LCN2, CTSB, GUSB, CLEC3B, HSPD1, PLAU
7	myocardial infarction	30.4	CST3
8	hepatitis	30.4	HSPD1, GUSB
9	pneumonia	30.4	CTSB, TLR4, LACTB
10	appendicitis	30.3	LCN2
11	tuberculosis	30.3	HSPD1, TLR1, GUSB, TLR4, LACTB
12	colorectal cancer	30.0	CHI3L1, GUSB, CTSB, CST3, PLAU, CLEC3B
13	adenoma	30.0	CYP11B1, TLR4, CTSB
14	ovarian disease	10.6
15	infertility	10.5
16	endometritis	10.5
17	gonorrhea	10.5
18	vaginal disease	10.5
19	vaginitis	10.5
20	bacterial vaginosis	10.4
21	urethritis	10.3
22	irritable bowel syndrome	10.3
23	uterine inflammatory disease	10.3
24	leukocyte disease	10.3
25	uterine disease	10.3
26	hepatitis a	10.2
27	fallopian tube disease	10.2
28	herpes simplex	10.2
29	vaginal discharge	10.2
30	fitz-hugh-curtis syndrome	10.2
31	genital herpes	10.0
32	ureteral obstruction	10.0
33	familial mediterranean fever	10.0
34	trichomoniasis	10.0
35	ovarian endometriosis	10.0
36	common wart	10.0
37	endocervicitis	10.0
38	small cell carcinoma	10.0
39	pancytopenia	10.0
40	vulvovaginitis	10.0
41	nocardiosis	10.0
42	ureterocele	10.0
43	portal vein thrombosis	10.0
44	acute female pelvic peritonitis	10.0
45	actinomycosis	10.0
46	peptic ulcer perforation	10.0
47	hepatic vein thrombosis	10.0
48	acute salpingitis	10.0
49	breast disease	10.0
50	cervical cancer	10.0

Graphical network of the top 20 diseases related to Pelvic Inflammatory Disease:

Clinical Features for Pelvic Inflammatory Disease

Drugs & Therapeutics for Pelvic Inflammatory Disease

Sources:
⁵CenterWatch, ⁴¹NIH Clinical Center, ⁶ClinicalTrials, ⁶⁰UMLS, ⁴⁰NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Pelvic Inflammatory Disease

Drug clinical trials:

Search ClinicalTrials for Pelvic Inflammatory Disease

Search NIH Clinical Center for Pelvic Inflammatory Disease

Search CenterWatch for Pelvic Inflammatory Disease

Genetic Tests for Pelvic Inflammatory Disease

Anatomical Context for Pelvic Inflammatory Disease

Sources:
³²MalaCards
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MalaCards organs/tissues related to Pelvic Inflammatory Disease:

³²

Ovary, Uterus, Testes, Skin, Breast, Monocytes, T cells, Colon

Animal Models for Pelvic Inflammatory Disease or affiliated genes

Sources:
³⁶MGI
See all sources

MGI Mouse Phenotypes related to Pelvic Inflammatory Disease:

³⁶

id	Description	MGI Source Accession	Score	Top Affiliating Genes
1	hematopoietic system phenotype	MP:0005397	9.3	CTSA, TLR4, LCN2, GUSB, HLA-DQA1, CYP11B1
2	renal/urinary system phenotype	MP:0005367	9.2	TLR4, CTSA, CTSB, GUSB, CYP11B1, LCN2
3	immune system phenotype	MP:0005387	9.0	PLAU, LCN2, TLR4, TLR1, CTSA, CTSB

Publications for Pelvic Inflammatory Disease

Sources:
⁵⁰PubMed
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Articles related to Pelvic Inflammatory Disease:

(show top 50) (show all 511)

id	Title	Authors	Year
1	Does bacterial vaginosis cause pelvic inflammatory disease? (23324974)	Taylor B.D.... Haggerty C.L.	2013
2	Markedly elevated soluble E-cadherin in plasma of patient with pelvic inflammatory disease. (23122825)	Tsai H.T.... Wang P.H.	2013
3	The role of the serum inflammatory markers for predicting the tubo-ovarian abscess in acute pelvic inflammatory disease: a single-center 5-year experience. (23104053)	Demirtas O.... Yilmaz H.	2013
4	Risk of pelvic inflammatory disease following Chlamydia trachomatis infection: analysis of prospective studies with a multistate model. (23813703)	Price M.J.... Horner P.J.	2013
5	Acute pelvic inflammatory disease, active component, U.S. Armed Forces, 2002-2011. (22876801)		2012
6	Small bowel obstruction secondary to pelvic inflammatory disease. (21679543)	Harris C.... Lambrianides A.L.	2011
7	Pelvic inflammatory disease and ovarian cancer. (22123593)	van de Laar R.... Massuger L.F.	2011
8	Adolescent and parental utilities for the health states associated with pelvic inflammatory disease. (22001169)	Trent M.... Frick K.D.	2011
9	Elevated plasma osteopontin level is associated with pelvic inflammatory disease. (20713973)	Wang P.H.... Yang S.F.	2010
10	Markedly elevated plasma myeloperoxidase protein in patients with pelvic inflammatory disease who have A allele myeloperoxidase gene polymorphism. (19147137)	Lee S.A.... Yang S.F.	2010
11	Chlamydia screening and pelvic inflammatory disease: Insights from exploratory time-series analyses. (20494242)	Owusu-Edusei K.... Kent C.K.	2010
12	Pelvic inflammatory disease and tubo-ovarian abscess. (18954759)	Lareau S.M.... Beigi R.H.	2008
13	Endometriosis and its coexistence with irritable bowel syndrome and pelvic inflammatory disease: findings from a national case-control study--Part 2. (18715239)	Seaman H.E.... de Vries C.S.	2008
14	An audit on the management of pelvic inflammatory disease in the West Midlands, UK. (17945054)	Walzman M.... Ross J.D.	2007
15	A serological study of the role of Mycoplasma genitalium in pelvic inflammatory disease and ectopic pregnancy. (17475688)	Jurstrand M.... Fredlund H.	2007
16	Computed tomographic features of appendiceal serositis in pelvic inflammatory disease: comparison with pathological findings. (17259841)	Kim M.Y.... Kim J.M.	2007
17	Managing pelvic inflammatory disease. (18705484)	Sivalingam N.... Loh K.Y.	2007
18	Pelvic inflammatory disease. (16973083)	Ross J.	2006
19	Hospitalizations for pelvic inflammatory disease and tuboovarian abscess. (16507932)	Paik C.K.... Sweet R.L.	2006
20	Reiter's syndrome and pelvic inflammatory disease in a couple. (16836507)	Serwin A.B.... Chodynicka B.	2006
21	Pelvic inflammatory disease in adolescents. (16932044)	Gray-Swain M.R.... Peipert J.F.	2006
22	Prediction of pelvic inflammatory disease among young, single, sexually active women. (16505735)	Ness R.B.... Bass D.C.	2006
23	Predictors of chronic pelvic pain in an urban population of women with symptoms and signs of pelvic inflammatory disease. (15849530)	Haggerty C.L.... Ness R.B.	2005
24	Pelvic inflammatory disease in adolescents: high incidence and recurrence rates in an urban teen clinic. (15603980)	Kelly A.M.... Aughey D.	2004
25	Intrauterine contraceptive devices and risk of pelvic inflammatory disease: standard of care in high STI prevalence settings. (15242222)	Steen R.... Shapiro K.	2004
26	A refined estimate of the lifetime cost of pelvic inflammatory disease. (15107638)	Rein D.B.... Gift T.L.	2004
27	Pelvic inflammatory disease and sepsis. (12597041)	Dulin J.D.... Akers M.C.	2003
28	Pelvic inflammatory disease: how should it be managed? (12821828)	Ross J.D.	2003
29	Randomized field trial of vaginal douching, pelvic inflammatory disease and pregnancy. (12859036)	Rothman K.J.... Dreyer N.A.	2003
30	Lower quality of life among women with chronic pelvic pain after pelvic inflammatory disease. (14672466)	Haggerty C.L.... Ness R.B.	2003
31	Ciprofloxacin-tinidazole combination, fluconazole- azithromicin-secnidazole-kit and doxycycline- metronidazole combination therapy in syndromic management of pelvic inflammatory disease: a prospective randomized controlled trial. (14701947)	Malhotra M.... Sharma S.	2003
32	The extended Chlamydia trachomatis diagnosis in patients with pelvic inflammatory disease--a better approach for the diagnosis of upper genital tract infections. (15285188)	Petersen E.E.... BAPttcher M.	2003
33	Observer agreement with laparoscopic diagnosis of pelvic inflammatory disease using photographs. (12738143)	Molander P.... Paavonen J.	2003
34	Efficacy and safety of azithromycin as monotherapy or combined with metronidazole compared with two standard multidrug regimens for the treatment of acute pelvic inflammatory disease. (12635534)	Bevan C.D.... Rothermel C.D.	2003
35	An audit of outpatient management of pelvic inflammatory disease. (12194744)	Piyadigamage A.... Wilson J.D.	2002
36	An update on pelvic inflammatory disease. (11872852)	Ross J.D.	2002
37	Transvaginal power Doppler findings in laparoscopically proven acute pelvic inflammatory disease. (11309174)	Molander P.... Cacciatore B.	2001
38	Clinical predictors of endometritis in women with symptoms and signs of pelvic inflammatory disease. (11303192)	Peipert J.F.... Bass D.C.	2001
39	Antibody response to the chlamydial heat-shock protein 60 in an experimental model of chronic pelvic inflammatory disease in monkeys (Macaca nemestrina). (10438366)	Peeling R.W.... Stamm W.E.	1999
40	Evaluation of ofloxacin in the treatment of laparoscopically documented acute pelvic inflammatory disease (salpingitis). (10371472)	Peipert J.F.... Rielly-Gauvin K.	1999
41	High prevalence of cervical intra-epithelial neoplasia in women treated for pelvic inflammatory disease. (9846714)	Giraud J.... Kerisit J.	1998
42	Pelvic inflammatory disease in Rhode Island: epidemiology, diagnosis and therapy. (9350116)	Peipert J.F.... Phipps M.G.	1997
43	Recurrent chlamydial infections increase the risks of hospitalization for ectopic pregnancy and pelvic inflammatory disease. (9024098)	Hillis S.D.... Mac Kenzie W.R.	1997
44	Pelvic inflammatory disease in HIV-positive women. (9142056)	Sweet R.L.... Landers D.V.	1997
45	Ascites--an unusual association with pelvic inflammatory disease. (9429721)	Gregora M.G.... McNamara T.	1997
46	Pelvic inflammatory disease. Correlation of severity with CA-125 levels. (8725760)	Moley K.H.... Mutch D.G.	1996
47	Recognition of tubo-ovarian abscess in adolescents with pelvic inflammatory disease. (8803731)	Slap G.B.... Driscoll D.A.	1996
48	Pelvic inflammatory disease in intrauterine device users. (9678122)	Beerthuizen R.J.	1996
49	Serum tetranectin in patients with acute pelvic inflammatory disease (PID). Correlation to clinical and laboratory findings. (7534970)	HA... Brihmer C.	1995
50	Gonorrhea, genital chlamydial infection, and nonspecific urethritis in male partners of women hospitalized and treated for acute pelvic inflammatory disease. (8511708)	Kamwendo F.... Danielsson D.	1993

Genes related to Pelvic Inflammatory Disease

Sources:
¹⁷GeneCards, ⁴⁵Novus Biologicals, ³¹LifeSpan BioSciences, Inc.
See all sources

Genes related to Pelvic Inflammatory Disease:

(show all 35)

id	Symbol	Description	Score	Implication
1	HSPD1	heat shock 60kDa protein 1 (chaperonin)	20.30	GeneCards inferred : Publications, Disorders (show sections)
2	TLR1	toll-like receptor 1	19.71	GeneCards inferred : Publications, Disorders (show sections)
3	MAN1B1	mannosidase, alpha, class 1B, member 1	19.14	GeneCards inferred : Publications, Disorders (show sections)
4	CTSA	cathepsin A	18.57	GeneCards inferred : Publications, Disorders (show sections)
5	CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)	18.00	GeneCards inferred : Publications, Disorders (show sections)
6	CYP11B1	cytochrome P450, family 11, subfamily B, polypeptide 1	17.43	GeneCards inferred : Disorders (show sections)
7	GUSB	glucuronidase, beta	16.86	GeneCards inferred : Publications, Disorders (show sections)
8	CST3	cystatin C	16.28	GeneCards inferred : Publications, Disorders (show sections)
9	PLAU	plasminogen activator, urokinase	15.71	GeneCards inferred : Publications, Disorders (show sections)
10	HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	15.14	GeneCards inferred : Publications, Disorders (show sections)
11	MFN2	mitofusin 2	14.57	GeneCards inferred : Disorders (show sections)
12	MTMR12	myotubularin related protein 12	14.00	GeneCards inferred : Disorders (show sections)
13	CTSB	cathepsin B	13.43	GeneCards inferred : Publications, Disorders (show sections)
14	TLR4	toll-like receptor 4	12.86	GeneCards inferred : Publications, Disorders (show sections)
15	LACTB	lactamase, beta	12.30	GeneCards inferred : Publications, Disorders (show sections)
16	CLEC3B	C-type lectin domain family 3, member B	11.71	GeneCards inferred : Publications, Disorders (show sections)
17	CETN1	centrin, EF-hand protein, 1	11.14	GeneCards inferred : Disorders (show sections)
18	RRS1	RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)	10.57	GeneCards inferred : Disorders (show sections)
19	OR10T2	olfactory receptor, family 10, subfamily T, member 2	10.00	GeneCards inferred : Disorders (show sections)
20	LCN2	lipocalin 2	9.43	GeneCards inferred : Publications, Disorders (show sections)
21	MPO	myeloperoxidase	8.86	GeneCards inferred : Publications, Disorders (show sections)
22	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	8.28	GeneCards inferred : Publications, Disorders (show sections)
23	CXCL12	chemokine (C-X-C motif) ligand 12	7.71	GeneCards inferred : Publications, Disorders (show sections)
24	MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	7.14	GeneCards inferred : Publications, Disorders (show sections)
25	PLAT	plasminogen activator, tissue	6.57	GeneCards inferred : Publications, Disorders (show sections)
26	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	6.00	GeneCards inferred : Publications, Disorders (show sections)
27	CCL2	chemokine (C-C motif) ligand 2	5.43	GeneCards inferred : Publications, Disorders (show sections)
28	IFNG	interferon, gamma	4.86	GeneCards inferred : Publications, Disorders (show sections)
29	MAPT	microtubule-associated protein tau	4.28	GeneCards inferred : Disorders (show sections)
30	CRP	C-reactive protein, pentraxin-related	3.71	GeneCards inferred : Disorders (show sections)
31	TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	2.86	GeneCards inferred : Publications (show sections)
32	TLR6	toll-like receptor 6	2.28	GeneCards inferred : Publications (show sections)
33	PLAUR	plasminogen activator, urokinase receptor	1.70	GeneCards inferred : Publications (show sections)
34	TLR2	toll-like receptor 2	1.12	GeneCards inferred : Publications (show sections)
35	CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.54	GeneCards inferred : Publications (show sections)

Products for genes related to Pelvic Inflammatory Disease disease:

id	Company	Proteins	Lysates	Antibodies
1	Novus Biologicals	35	35	35
2	LSBio	-	-	35

Genetic Variations for Pelvic Inflammatory Disease

Expression for genes affiliated with Pelvic Inflammatory Disease

Sources:
¹BioGPS, ¹⁵Gene Expression Omnibus DataSets
See all sources

Expression patterns in normal tissues for genes affiliated with Pelvic Inflammatory Disease

Search GEO for disease gene expression data for Pelvic Inflammatory Disease.

Pathways for genes affiliated with Pelvic Inflammatory Disease

Sources:
⁵³Reactome, ²⁹KEGG
See all sources

Pathways related to Pelvic Inflammatory Disease according to GeneCards/GeneDecks:

id	Super pathways (with members indented)	Score	Top Affiliating Genes
1	MHC class II antigen presentation⁵³	10.0	HLA-DQA1, CTSB, CTSA
2	Immune response Bacterial infections in normal airways	10.0	TLR4, TLR1, CTSB
3	TRAF6 Mediated Induction of proinflammatory cytokines⁵³ Hide members Toll-Like Receptors Cascades⁵³ Toll Like Receptor TLR1:TLR2 Cascade⁵³ Toll Like Receptor 2 (TLR2) Cascade⁵³ Toll Like Receptor 4 (TLR4) Cascade⁵³ Toll Like Receptor TLR6:TLR2 Cascade⁵³ Activated TLR4 signalling⁵³ MyD88:Mal cascade initiated on plasma membrane⁵³ TRIF-mediated TLR3/TLR4 signaling ⁵³ Toll Like Receptor 3 (TLR3) Cascade⁵³ MyD88-independent cascade ⁵³	10.0	CTSB, TLR1, TLR4
4	Tuberculosis²⁹	9.9	HLA-DQA1, TLR1, TLR4, HSPD1

Compounds for genes affiliated with Pelvic Inflammatory Disease

Sources:
⁴⁴Novoseek, ⁵⁹Tocris Bioscience, ²⁸IUPHAR, ⁴⁹PharmGKB, ¹¹DrugBank, ²⁴HMDB, ²BitterDB
See all sources

Compounds related to Pelvic Inflammatory Disease according to GeneCards/GeneDecks:

(show all 38)

id	Compound	Score	Top Affiliating Genes
1	cycloheximide⁴⁴	10.6	HSPD1
2	ninhydrin⁴⁴	10.6	CTSB, CTSA
3	bifidobacterium⁴⁴	10.5	GUSB, HSPD1
4	pam2csk4⁵⁹	10.5	TLR4, TLR1
5	pam3csk4⁵⁹	10.5	TLR4, TLR1
6	poly(i:c)⁵⁹	10.5	TLR4, TLR1
7	aspartate⁴⁴	10.5	GUSB, CST3, HSPD1
8	flagellin⁴⁴ ²⁸	11.5	HSPD1, TLR4, TLR1
9	actinidin⁴⁴	10.4	CST3, CTSB
10	resiquimod⁴⁴ ⁵⁹	11.4	TLR1, TLR4
11	leupeptin⁴⁴	10.4	PLAU, CTSB, CST3
12	dexamethasone⁴⁴ ⁴⁹ ²⁸ ¹¹	13.4	TLR4, CYP11B1, CLEC3B
13	doxycycline⁴⁴ ¹¹	11.3	LACTB, PLAU, HSPD1
14	guanidine hydrochloride⁴⁴	10.3	PLAU, CTSB, HSPD1
15	mannose 6-phosphate⁴⁴ ²⁴	11.3	CTSA, CTSB, GUSB, PLAU
16	Alpha-D-Mannose¹¹	10.3	LCN2, GUSB, CHI3L1, MAN1B1
17	vancomycin⁴⁴ ¹¹	11.3	CST3, LACTB
18	e 64d⁴⁴ ⁵⁹	11.3	CTSB, CTSA
19	kininogen⁴⁴	10.2	PLAU, CLEC3B, CTSB, CST3
20	gold⁴⁴	10.2	HSPD1, LCN2, CST3, CTSB
21	aprotinin⁴⁴ ¹¹	11.2	PLAU, CTSB, CST3
22	chloroquine⁴⁴ ² ⁴⁹ ²⁸ ¹¹	14.1	PLAU, CTSB, TLR4
23	glutamine⁴⁴	10.1	HSPD1, CST3, CTSB, CYP11B1, PLAU
24	fmlp⁴⁴	10.1	CLEC3B, GUSB, TLR4, LCN2
25	n acetylcysteine⁴⁴	10.1	HSPD1, TLR4, CST3, PLAU
26	latex⁴⁴	10.1	CST3, TLR4, HSPD1
27	cisplatin⁴⁴ ⁴⁹ ⁵⁹ ¹¹	13.1	HSPD1, TLR4, CST3, CTSB, PLAU
28	superoxide⁴⁴ ²⁴	11.0	HSPD1, LCN2, TLR4, CST3, GUSB
29	iron⁴⁴ ²⁴	11.0	HSPD1, LCN2, TLR4, CST3, CTSB
30	lactate⁴⁴	10.0	HSPD1, TLR4, CST3, CTSB, GUSB, PLAU
31	creatinine⁴⁴	10.0	HSPD1, LCN2, CST3, CTSB, GUSB, PLAU
32	fibrinogen⁴⁴	9.9	HSPD1, LCN2, TLR4, CST3, CTSB, PLAU
33	doxorubicin⁴⁴ ⁴⁹ ¹¹	11.9	PLAU, GUSB, CTSB, HSPD1
34	polysaccharide⁴⁴	9.9	HSPD1, LCN2, TLR4, CST3, CLEC3B, PLAU
35	alanine⁴⁴	9.9	HSPD1, TLR4, CST3, CTSB, CYP11B1, PLAU
36	serine⁴⁴	9.7	LACTB, CTSB, TLR4
37	cholesterol⁴⁴ ²⁸ ¹¹ ²⁴	12.7	HSPD1, TLR4, CST3, CTSB, CYP11B1
38	calcium⁴⁴ ⁴⁹ ¹¹ ²⁴	12.3	HSPD1, LCN2, TLR4, CST3, CTSB, GUSB

GO Terms for genes affiliated with Pelvic Inflammatory Disease

Sources:
¹⁶Gene Ontology
See all sources

Cellular components related to Pelvic Inflammatory Disease according to GeneCards/GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	lipopolysaccharide receptor complex	GO:046696	9.9	HSPD1, TLR4
2	mitochondrion	GO:005739	9.6	LACTB, CYP11B1, MFN2, CTSB, CTSA, HSPD1
3	extracellular space	GO:005615	9.3	PLAU, CLEC3B, CHI3L1, CTSB, CST3, LCN2

Biological processes related to Pelvic Inflammatory Disease according to GeneCards/GeneDecks:

(show all 8)

id	Name	GO ID	Score	Top Affiliating Genes
1	regulation of cytokine secretion	GO:050707	10.4	TLR1, TLR4
2	macrophage activation	GO:042116	10.3	TLR1, TLR4
3	positive regulation of tumor necrosis factor biosynthetic process	GO:042535	10.3	TLR1, TLR4
4	positive regulation of interferon-alpha production	GO:032727	10.2	HSPD1, TLR4
5	MyD88-dependent toll-like receptor signaling pathway	GO:002755	10.2	HSPD1, TLR4, TLR1
6	T-helper 1 type immune response	GO:042088	10.1	TLR1, TLR4
7	immune response	GO:006955	9.9	CYP11B1, HLA-DQA1, TLR1, TLR4
8	positive regulation of interleukin-10 production	GO:032733	9.9	TLR4, HSPD1

Molecular functions related to Pelvic Inflammatory Disease according to GeneCards/GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	lipopolysaccharide binding	GO:001530	10.2	TLR4, HSPD1

Products for genes affiliated with Pelvic Inflammatory Disease

Antibodies
Proteins
Lysates

Antibodies

Sources for Pelvic Inflammatory Disease

¹BioGPS

²BitterDB

³CDC

⁴Cell Signaling Technology

⁵CenterWatch

⁶ClinicalTrials

⁷dbSNP

⁸Disease Ontology

⁹diseasecard

¹⁰DISEASES

¹¹DrugBank

¹²EMD Millipore

¹³ExPASy

¹⁴FMA

¹⁵Gene Expression Omnibus DataSets

¹⁶Gene Ontology

¹⁷GeneCards

¹⁸GeneDecks

¹⁹GeneReviews

²⁰GeneTests

²¹Genetics Home Reference

²²GTR

²³HGMD

²⁴HMDB

²⁵ICD10

²⁶ICD10 via Orphanet

²⁷ICD9CM

²⁸IUPHAR

²⁹KEGG

³⁰LifeMap Discovery™

³¹LifeSpan BioSciences, Inc.

³²MalaCards

³³MedlinePlus

³⁴MeSH

³⁵MESH via Orphanet

³⁶MGI

³⁷NCBI BioSystems Database

³⁸NCBI Bookshelf

³⁹NCIt

⁴⁰NDF-RT

⁴¹NIH Clinical Center

⁴²NIH Rare Diseases

⁴³NINDS

⁴⁴Novoseek

⁴⁵Novus Biologicals

⁴⁶OMIM

⁴⁷OMIM via Orphanet

⁴⁸Orphanet

⁴⁹PharmGKB

⁵⁰PubMed

⁵¹QIAGEN

⁵²R&D Systems

⁵³Reactome

⁵⁴SABiosciences

⁵⁵SinoBiological

⁵⁶SNOMED-CT

⁵⁷SNOMED-CT via Orphanet

⁵⁸Thomson Reuters

⁵⁹Tocris Bioscience

⁶⁰UMLS

⁶¹UMLS via Orphanet

⁶²UniProtKB/Swiss-Prot

⁶³Wikipedia

PID MCID: PLV003 MIFTS: 56	Pelvic Inflammatory Disease (PID) malady Reproductive diseases category
35 genes, 8 tissues, 132 related diseases, clinical trials.

Pelvic Inflammatory Disease (PID) malady