MCID: PLV003
MIFTS: 51

Pelvic Inflammatory Disease

Categories: Reproductive diseases

Aliases & Classifications for Pelvic Inflammatory Disease

Summaries for Pelvic Inflammatory Disease

MedlinePlus : 41 pelvic inflammatory disease (pid) is an infection and inflammation of the uterus, ovaries, and other female reproductive organs. it causes scarring in these organs. this can lead to infertility, ectopic pregnancy, pelvic pain, abscesses, and other serious problems. pid is the most common preventable cause of infertility in the united states. gonorrhea and chlamydia, two sexually transmitted diseases, are the most common causes of pid. other bacteria can also cause it. you are at greater risk if you are sexually active and younger than 25 have more than one sex partner douche some women have no symptoms. others have pain in the lower abdomen, fever, smelly vaginal discharge, irregular bleeding, and pain during intercourse or urination. doctors diagnose pid with a physical exam, lab tests, and imaging tests. antibiotics can cure pid. early treatment is important. waiting too long increases the risk of infertility. nih: national institute of allergy and infectious diseases

MalaCards based summary : Pelvic Inflammatory Disease, also known as pid, is related to chlamydia and myocardial infarction, and has symptoms including fever, pelvic pain and pruritus. An important gene associated with Pelvic Inflammatory Disease is CRP (C-Reactive Protein), and among its related pathways/superpathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. The drugs Clindamycin and Levofloxacin have been mentioned in the context of this disorder. Affiliated tissues include ovary, uterus and testes, and related phenotypes are cardiovascular system and hematopoietic system

CDC : 3 Basic Fact Sheet | Detailed Version

Wikipedia : 72 Pelvic inflammatory disease or pelvic inflammatory disorder (PID) is an infection of the upper part of... more...

Related Diseases for Pelvic Inflammatory Disease

Diseases related to Pelvic Inflammatory Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 144)
id Related Disease Score Top Affiliating Genes
1 chlamydia 31.3 CD40LG HSPD1
2 myocardial infarction 28.5 CCL2 CD40LG CRP CXCL12 MMP9 TLR4
3 fitz-hugh-curtis syndrome 11.3
4 salpingitis 11.2
5 peritonitis 11.2
6 benign multicystic peritoneal mesothelioma 10.8
7 solitary cyst of breast 10.7 CRP MMP9
8 acquired polycythemia 10.7 CD40LG CRP
9 cannabis dependence 10.7 CD40LG CRP
10 oculo-cerebral dysplasia 10.7 CD40LG TLR1
11 chronic mucocutaneous candidiasis 10.6 CD40LG CRP
12 rocky mountain spotted fever 10.6 CD40LG CRP
13 epididymis adenocarcinoma 10.6 CD40LG MMP9
14 myelomeningocele 10.6 CRP TLR4
15 prothrombin thrombophilia 10.5 TLR2 TLR4
16 gonococcal synovitis 10.5 CD40LG TLR4
17 emphysema, congenital lobar 10.5 CD40LG CRP MMP9
18 beach ear 10.5 CD40LG CRP
19 partial circumpapillary choroid dystrophy 10.5 CD40LG CRP
20 neutrophil-specific granule deficiency 10.4 TLR1 TLR2 TLR6
21 fanconi syndrome 10.4 TLR2 TLR4
22 urethral intrinsic sphincter deficiency 10.4 CCL2 MMP9
23 follicular mucinosis 10.4 CD40LG MMP9 TLR4
24 epidermolysis bullosa dystrophica, ad 10.4 CRP TIRAP TLR2
25 glycogen storage disease viii 10.4 CD40LG CRP TLR4
26 esophagus melanoma 10.4 CD40LG CRP TLR4
27 spotted fever 10.4 CD40LG HSPD1
28 inner ear disease 10.4 CD40LG TLR1 TLR4
29 aspartylglucosaminuria 10.4 CD40LG TLR1 TLR2
30 common cold 10.4 CD40LG TLR4 TLR6
31 melioidosis 10.4 TLR1 TLR2 TLR4
32 rickettsialpox 10.3 CD40LG TLR2 TLR4
33 thymus clear cell carcinoma 10.3 CRP TLR2 TLR4
34 alkhurma hemorrhagic fever 10.3 CD40LG TLR2 TLR4
35 glossopharyngeal nerve disease 10.3 CCL2 CRP MMP9
36 muscle tissue disease 10.3 CD40LG CHI3L1 CRP
37 testicular infarct 10.3 CD40LG TLR2 TLR4
38 tuberculum sellae meningioma 10.3 CD40LG CRP TLR4
39 nasopharyngitis 10.3 CD40LG TLR2 TLR4
40 dermatitis herpetiformis, familial 10.3 CCL2 CD40LG CRP
41 pancreatic acth hormone producing tumor 10.3 CCL2 CRP MMP9
42 mesenchymal cell neoplasm 10.3 CCL2 CD40LG CRP
43 leiomyosarcoma 10.3 CD40LG CRP HSPD1
44 mycobacterium kansasii 10.3 TLR1 TLR2
45 pancreatic vasoactive intestinal peptide producing tumor 10.3 CD40LG CRP HSPD1
46 premature ovarian failure 12 10.3 CD40LG TLR2 TLR4
47 tumefactive multiple sclerosis 10.3 CCL2 MMP9 TLR2
48 calcinosis 10.3 CCL2 CD40LG CRP
49 causalgia 10.2 CCL2 CD40LG MMP9
50 chickenpox 10.2 CCL2 CD40LG CRP

Comorbidity relations with Pelvic Inflammatory Disease via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Pelvic Inflammatory Disease:



Diseases related to Pelvic Inflammatory Disease

Symptoms & Phenotypes for Pelvic Inflammatory Disease

UMLS symptoms related to Pelvic Inflammatory Disease:


fever, pelvic pain, pruritus

MGI Mouse Phenotypes related to Pelvic Inflammatory Disease:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.02 CD40LG CRP CTSA CXCL12 HLA-DQB1 MMP9
2 hematopoietic system MP:0005397 10 CD40LG CHI3L1 CTSA CXCL12 HLA-DQB1 MMP9
3 cellular MP:0005384 9.97 CD40LG CHI3L1 CTSA CXCL12 HLA-DQB1 HSPD1
4 immune system MP:0005387 9.97 HLA-DQB1 MMP9 TIRAP TLR1 TLR2 TLR4
5 renal/urinary system MP:0005367 9.43 CD40LG CTSA HLA-DQB1 MMP9 TLR2 TLR4
6 reproductive system MP:0005389 9.23 CXCL12 HLA-DQB1 HSPD1 MMP9 TLR4 TLR6

Drugs & Therapeutics for Pelvic Inflammatory Disease

Drugs for Pelvic Inflammatory Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 110)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clindamycin Approved, Vet_approved Phase 4 18323-44-9 29029
2
Levofloxacin Approved, Investigational Phase 4,Phase 3 100986-85-4 149096
3
Metronidazole Approved Phase 4,Phase 3,Phase 2 443-48-1 4173
4
Ofloxacin Approved Phase 4,Phase 3 82419-36-1 4583
5
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3 50-28-2 5757
6
Ethinyl Estradiol Approved Phase 4,Phase 3 57-63-6 5991
7
Moxifloxacin Approved, Investigational Phase 4,Phase 3 354812-41-2, 151096-09-2 152946
8
Norgestimate Approved Phase 4,Phase 3 35189-28-7 6540478
9
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 2 564-25-0 54671203
10
Povidone Approved Phase 4,Phase 3 9003-39-8
11 Povidone-iodine Approved Phase 4,Phase 3 25655-41-8
12
Ethanol Approved Phase 4 64-17-5 702
13
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613 2171
14
Azithromycin Approved Phase 4,Phase 3 83905-01-5 55185 53477736 447043
15
Cefazolin Approved Phase 4 25953-19-9 656510 33255
16
Copper Approved Phase 4 7440-50-8 27099
17
Iodine Investigational Phase 4,Phase 3 7553-56-2 807
18 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1
19 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
20 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2
21 Antitubercular Agents Phase 4,Phase 2,Phase 3
22 Clindamycin palmitate Phase 4
23 Clindamycin phosphate Phase 4
24 Gentamicins Phase 4,Phase 2,Phase 3
25 Antiparasitic Agents Phase 4,Phase 3,Phase 2
26 Antiprotozoal Agents Phase 4,Phase 3,Phase 2
27 Cytochrome P-450 CYP1A2 Inhibitors Phase 4,Phase 3
28 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3
29 Renal Agents Phase 4,Phase 3
30 Topoisomerase Inhibitors Phase 4,Phase 3
31 Contraceptive Agents Phase 4,Phase 3
32 Contraceptives, Oral Phase 4,Phase 3
33 Contraceptives, Oral, Combined Phase 4,Phase 3
34 Estradiol 17 beta-cypionate Phase 4,Phase 3
35 Estradiol 3-benzoate Phase 4,Phase 3
36 Estradiol valerate Phase 4,Phase 3 979-32-8
37 Fluoroquinolones Phase 4,Phase 3
38 Norgestimate, ethinyl estradiol drug combination Phase 4,Phase 3
39 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 3
40 Polyestradiol phosphate Phase 4,Phase 3
41 Antimalarials Phase 4,Phase 2
42 Anti-Infective Agents, Local Phase 4,Phase 3
43 Blood Substitutes Phase 4,Phase 3
44 cadexomer iodine Phase 4,Phase 3
45 Micronutrients Phase 4,Phase 3
46 Pharmaceutical Solutions Phase 4,Phase 3,Phase 1
47 Plasma Substitutes Phase 4,Phase 3
48 Trace Elements Phase 4,Phase 3
49 Central Nervous System Depressants Phase 4
50 Estrogens Phase 4

Interventional clinical trials:

(show top 50) (show all 77)

id Name Status NCT ID Phase Drugs
1 To Compare Ofloxacin With Azitromycin for Pelvic Inflammatory Disease (PID) Treatment Completed NCT01241110 Phase 4 Ofloxacin group A, Azitromycin group B;azitromycin
2 Moxifloxacin Versus Ofloxacin Plus Metronidazole in Uncomplicated Pelvic Inflammatory Disease: Multicenter Randomized Controlled Trials Completed NCT01799356 Phase 4 Moxifloxacin;Ofloxacin;Metronidazole
3 Doxycycline Prophylaxis at Vacuum Aspiration Trial Completed NCT00547170 Phase 4 Doxycycline pre-operatively;Doxycycline post-operatively
4 Does Preoperative Vaginal Preparation With Povidone-iodine Before Cesarean Delivery Reduce the Risk of Endometritis? Completed NCT01437228 Phase 4 povidone- iodine solution.;placebo
5 Homeopathic Treatment of Chronic Pelvic Pain in Women With Endometriosis Completed NCT02427386 Phase 4 dynamized estrogen;placebo
6 Surgical Success After Laparoscopic vs Abdominal Hysterectomy Recruiting NCT01793584 Phase 4
7 Preoperative Vaginal Cleansing With Povidone Iodine and the Risk of Post Cesarean Endometritis Recruiting NCT02693483 Phase 4 10% povidone iodine
8 Comparison Between Intrauterine Contraceptive Device Insertion During Cesarean Section Vs Conventional Application Enrolling by invitation NCT02674139 Phase 4
9 Antibiotic Prophlaxis for High-risk Laboring Women in Low Income Countries Not yet recruiting NCT03248297 Phase 4 Azithromycin;Azithromycin and amoxicillin;Placebo
10 Treatment Utility of Postpartum Antibiotics in Chorioamnionitis Terminated NCT01585129 Phase 4 Postpartum Antibiotics;No postpartum antibiotics
11 Comparison Study of Cefazolin Versus Cefazolin Plus Azithromycin Prophylaxis in Post-Cesarean Endometritis Withdrawn NCT01721616 Phase 4 Azithromycin;Cefazolin
12 A Trial Comparing Moxifloxacin Versus Levofloxacin Plus Metronidazole In Uncomplicated Pelvic Inflammatory Disease Completed NCT00453349 Phase 3 Moxifloxacin (Avelox, BAY12-8039);Levofloxacin & Metronidazole
13 Uncomplicated Pelvic Inflammatory Disease. Treatment With Moxifloxacin. Completed NCT00683865 Phase 3 Ofloxacin;Avelox (Moxifloxacin, BAY12-8039)
14 Study Of Azithromycin Intravenous Formulation Against Pelvic Inflammatory Disease (PID) In Japan Completed NCT00871494 Phase 3 Azithromycin
15 A Phase 3 Study Of Intravenous Metronidazole For Intrabdominal Infection Completed NCT01473836 Phase 3 Metronidazole;Ceftriaxone sodium
16 Home Screening for Chlamydia Surveillance Completed NCT00177437 Phase 3
17 Vasopressin Versus Epinephrine in Myomectomy Completed NCT01861015 Phase 3 Epinephrine;Vasopressin
18 Antibiotic Prophylaxis in Prelabor Rupture of Membranes at Term Completed NCT01633294 Phase 2, Phase 3 Ampicillin + gentamicin
19 Chlorhexidine Gluconate vs Povidone-Iodine Vaginal Cleansing Solution Prior to Cesarean Delivery Recruiting NCT02915289 Phase 3
20 Empiric Therapy of Mucopurulent Cervicitis (MPC) Terminated NCT01072136 Phase 3 Azithromycin;Cefixime
21 The Importance of Anti-anaerobic Therapy for Acute Pelvic Inflammatory Disease (PID) Completed NCT01160640 Phase 2 Ceftriaxone;Doxycycline;Metronidazole;Placebo Oral Capsule
22 An Investigational Agent for the Treatment of Complicated Intra-Abdominal Infections or Acute Pelvic Infections (0826-038) Completed NCT00092170 Phase 2 MK0826, ertapenem sodium;Comparator: Ticarcillin/Clavulanate
23 Use of Essure® Micro-inserts in Women With Hydrosalpinx Prior to In Vitro Fertilization: A Prospective, Multicenter, International Feasibility Study Completed NCT01221974 Phase 1, Phase 2
24 The Clinical Effect of Fuke Qianjin Capsule on Chronic Pelvic Pain Caused by Pelvic Inflammation Recruiting NCT03251560 Phase 2 Fuke Qianjin capsule;Placebo oral capsule
25 The Efficacy and Safety of the Xue-Fu-Zhu-Yu Capsule in Treatment of Qi Stagnation and Blood Stasis Syndrome. Recruiting NCT03091634 Phase 2 xue-fu-zhu-yu capsule;xue-fu-zhu-yu capsule simulated agent
26 Hysteroscopic Tubal Occlusion Using Iso-Amyl 2-Cyano Acrylate (Amcrylate) in Patients With Hydrosalpinx Recruiting NCT02977234 Phase 1, Phase 2 Isoamyl 2-Cyanoacrylate
27 Clinical Research of TCM on Pelvic Inflammatory Disease Sequelae Not yet recruiting NCT02972151 Phase 2 Comprehensive treatment of TCM
28 The Optimal Time for Intravenous Antibiotic Prophylaxis in Elective Cesarean Section Not yet recruiting NCT02742948 Phase 2 ceftriaxone
29 Ultrasound-guided Hydrosalpinx Aspiration During Egg Collection Terminated NCT00566956 Phase 2
30 First in Human Study to Investigate the Safety, Tolerability, Pharmacokinetics and to Explore Pharmacodynamics of BAY1834845 Recruiting NCT03054402 Phase 1 BAY1834845;Placebo
31 Pharmacokinetics and Safety of Ertapenem in the Postpartum Period Terminated NCT01587495 Phase 1 Ertapenem
32 Prophylactic Antibiotics for Manual Removal of Retained Placenta in Vaginal Birth: a Randomized Controlled Trial Unknown status NCT01945450 Antibiotic prophylaxis;Ampicillin;Gentamycin;Clindamycin
33 Rate of Pelvic Inflammatory Disease at St. Michael's Hospital Completed NCT00783419
34 Community-Based Trial of Screening for Chlamydia Trachomatis to Prevent Pelvic Inflammatory Disease Completed NCT00115388
35 Improving Primary Care Follow-up for Patients With Pelvic Inflammatory Disease Completed NCT01299259
36 Drug Use Investigation Of Azithromycin IV For Pneumonia Or Pelvic Inflammatory Disease (Regulatory Post Marketing Commitment Plan) Completed NCT01671280 Azithromycin IV
37 The Role of Novel Organisms in Acute Endometritis Completed NCT01236131
38 To Compare the Strategies of Universal Antibiotic Prophylaxis Versus Screen-and-treat in Reducing Infective Complications and Re-infection in Women Who Undergo Termination of Pregnancy Completed NCT01842100 Universal antibiotic prophylaxis
39 Immunopathogenesis of Chlamydia Completed NCT00607659
40 Risk of Acute Liver Injury in Users of Antimicrobials Completed NCT01434173 Moxifloxacin (Avelox, BAY12-8039);Amoxicillin, Amoxicillin plus clavulanic acid, Cefuroxime, Clarithromycin, Doxycycline, Levofloxacin, Telithromycin
41 Recurrent Bacterial Vaginosis and Vaginal Acidifying Gel Trial Completed NCT00545181 Vaginal acidifying gel (RepHresh);Metronidazole control
42 Home Sampling Versus Conventional Sampling for Screening of Urogenital Chlamydia Trachomatis in Young Men and Women. Completed NCT00283127
43 Longitudinal Study of Vaginal Flora Completed NCT00340275
44 A Comparison of Narrow Band Imaging (NBI) and Standard White Light Laporoscopy to Detect Endometriosis Completed NCT01464775
45 Mirena Post-marketing Surveillance in Japan Completed NCT01414140 Levonorgestrel IUS (Mirena, BAY86-5028)
46 Special Investigation Of Azithromycin IV For Legionnaires' Disease (Regulatory Post Marketing Commitment Plan) Completed NCT01784770 Azithromycin IV
47 Minimal Invasive Strategies for Good and Complete Response to Chemoradiation in Rectal Cancer Completed NCT00939666
48 Quick Start Insertion of Mirena and ParaGard Completed NCT01730911
49 Bacterial Vaginosis Screening at IUD Insertion Completed NCT00802386
50 Efficacy of Dead Sea Peloid Gel in Chronic Endometritis Completed NCT02680275 Dead Sea Peloid Gel

Search NIH Clinical Center for Pelvic Inflammatory Disease

Cochrane evidence based reviews: pelvic inflammatory disease

Genetic Tests for Pelvic Inflammatory Disease

Anatomical Context for Pelvic Inflammatory Disease

MalaCards organs/tissues related to Pelvic Inflammatory Disease:

39
Ovary, Uterus, Testes, Liver, Placenta, Neutrophil, T Cells

Publications for Pelvic Inflammatory Disease

Articles related to Pelvic Inflammatory Disease:

(show top 50) (show all 611)
id Title Authors Year
1
Pelvic inflammatory disease and salpingitis: incidence of primary and repeat episodes in England. ( 27678278 )
2017
2
Postpartum tubo-ovarian abscess, likely arising from pelvic inflammatory disease during pregnancy. ( 28408537 )
2017
3
Efficacy and safety of morinidazole in pelvic inflammatory disease: results of a multicenter, double-blind, randomized trial. ( 28265816 )
2017
4
Pelvic inflammatory disease due to Streptococcus pneumoniae. ( 28807391 )
2017
5
Pelvic inflammatory disease and the risk of ovarian cancer: a meta-analysis. ( 28342087 )
2017
6
How to differentiate acute pelvic inflammatory disease from acute appendicitis ? A decision tree based on CT findings. ( 28894927 )
2017
7
Prevalence of Pelvic Inflammatory Disease in Sexually Experienced Women of Reproductive Age - United States, 2013-2014. ( 28125569 )
2017
8
Pelvic Inflammatory Disease and the Risk of Ovarian Cancer and Borderline Ovarian Tumors: A Pooled Analysis of 13 Case-Control Studies. ( 27941069 )
2017
9
Whole-Exome Sequencing to Identify Novel Biological Pathways Associated With Infertility After Pelvic Inflammatory Disease. ( 27898568 )
2017
10
A Community Based Study on Pelvic Inflammatory Disease in Postmenopausal Females: Microbiological Spectrum and Socio-Demographic Correlates. ( 28511414 )
2017
11
What Antibiotic Regimen Is Most Efficacious in Treating Pelvic Inflammatory Disease? ( 28822590 )
2017
12
Is Pelvic Inflammatory Disease a Risk Factor for Ovarian Cancer? ( 27672055 )
2017
13
Current perspectives in the USA on the diagnosis and treatment of pelvic inflammatory disease in adolescents. ( 28721112 )
2017
14
Anti-inflammatory Effects of the Natural Compounds Cortex Phellodendri and Humulus japonicus on Pelvic Inflammatory Disease in Mice. ( 28824307 )
2017
15
The potential role of infectious agents and pelvic inflammatory disease in ovarian carcinogenesis. ( 28529540 )
2017
16
Mesenchymal Stem Cells in Restoration of Fertility at Experimental Pelvic Inflammatory Disease. ( 28928773 )
2017
17
Clinical characteristics of genital chlamydia infection in pelvic inflammatory disease. ( 28086838 )
2017
18
Pelvic Inflammatory Disease in a Pediatric Emergency Department: Epidemiology and Treatment. ( 28441241 )
2017
19
Socioeconomic status of parents and the occurrence of pelvic inflammatory disease among undergraduates attending Irrua Specialist Teaching Hospital, Irrua, Edo State, Nigeria. ( 28762367 )
2017
20
Comparison of the population excess fraction of Chlamydia trachomatis infection on pelvic inflammatory disease at 12-months in the presence and absence of chlamydia testing and treatment: Systematic review and retrospective cohort analysis. ( 28199392 )
2017
21
Pelvic inflammatory disease. ( 28098673 )
2017
22
Evaluation of pelvic inflammatory disease potential in cholinesterase inhibitor pesticide-exposed females. ( 28497326 )
2017
23
Antibiotic therapy for pelvic inflammatory disease. ( 28436019 )
2017
24
Proportion of Pelvic Inflammatory Disease Cases Caused by Chlamydia trachomatis: Consistent Picture From Different Methods. ( 27260786 )
2016
25
Identification of novel microbes associated with pelvic inflammatory disease and infertility. ( 26825087 )
2016
26
MDCT of pelvic inflammatory disease: a review of the pathophysiology, gamut of imaging findings, and treatment. ( 27646971 )
2016
27
Risk of uterine, ovarian and breast cancer following pelvic inflammatory disease: a nationwide population-based retrospective cohort study. ( 27809870 )
2016
28
Improving Adolescent Pelvic Inflammatory Disease Follow-up From the Emergency Department: Randomized Controlled Trial With Text Messages. ( 26686262 )
2016
29
Pelvic Inflammatory Disease: Diagnosis And Treatment In The Emergency Department. ( 27879197 )
2016
30
Usefulness of Serum Procalcitonin Levels in Predicting Tubo-Ovarian Abscess in Patients with Acute Pelvic Inflammatory Disease. ( 27592364 )
2016
31
Invited Commentary on "Pelvic Inflammatory Disease," with Response from Dr Revzin and Colleagues. ( 27618332 )
2016
32
Pelvic inflammatory disease: improving awareness, prevention, and treatment. ( 27578991 )
2016
33
Population attributable fraction of pelvic inflammatory disease associated with chlamydia and gonorrhoea: a cross-sectional analysis of Australian sexual health clinic data. ( 27091729 )
2016
34
Characteristics of pelvic inflammatory disease where no sexually transmitted infection is identified: a cross-sectional analysis of routinely collected sexual health clinic data. ( 27091727 )
2016
35
Updated French guidelines for diagnosis and management of pelvic inflammatory disease. ( 27170602 )
2016
36
Pelvic inflammatory disease. ( 27107781 )
2016
37
Association Between Reduced Risk of Intracerebral Hemorrhage and Pelvic Inflammatory Disease. ( 26844517 )
2016
38
Fitz-Hugh-Curtis syndrome lacking typical characteristics of pelvic inflammatory disease. ( 27335367 )
2016
39
Increased risk of borderline ovarian tumors in women with a history of pelvic inflammatory disease: A nationwide population-based cohort study. ( 27549433 )
2016
40
Reproductive outcomes of patients being hospitalised with pelvic inflammatory disease. ( 27750467 )
2016
41
Assessing Trends in Chlamydia Positivity and Gonorrhea Incidence and Their Associations With the Incidence of Pelvic Inflammatory Disease and Ectopic Pregnancy in Washington State, 1988-2010. ( 26656441 )
2016
42
Pelvic inflammatory disease increases the risk of a second primary malignancy in patients with cervical cancer treated by surgery alone. ( 27893679 )
2016
43
Recruitment of Minority Adolescents and Young Adults into Randomised Clinical Trials: Testing the Design of the Technology Enhanced Community Health Nursing (TECH-N) Pelvic Inflammatory Disease Trial. ( 27617108 )
2016
44
Disseminated histoplasmosis presenting as pelvic inflammatory disease. ( 26783441 )
2016
45
Pelvic inflammatory disease: diagnosis and treatment in the emergency department [digest]. ( 28745849 )
2016
46
Gas chromatography-mass spectrometric method-based urine metabolomic profile of rats with pelvic inflammatory disease. ( 27168785 )
2016
47
Group A streptococcal toxic shock syndrome secondary to necrotizing pelvic inflammatory disease in a postmenopausal woman. ( 27419069 )
2016
48
Pelvic Inflammatory Disease: Multimodality Imaging Approach with Clinical-Pathologic Correlation. ( 27618331 )
2016
49
Risk of psychiatric disorders following pelvic inflammatory disease: a nationwide population-based retrospective cohort study. ( 26821967 )
2016
50
MRI in pelvic inflammatory disease: a pictorial review. ( 27933478 )
2016

Variations for Pelvic Inflammatory Disease

Expression for Pelvic Inflammatory Disease

Search GEO for disease gene expression data for Pelvic Inflammatory Disease.

Pathways for Pelvic Inflammatory Disease

Pathways related to Pelvic Inflammatory Disease according to GeneCards Suite gene sharing:

(show all 28)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.81 CCL2 CD40LG CHI3L1 CRP CTSA HLA-DQB1
2
Show member pathways
13.37 CD40LG CTSA HLA-DQB1 TIRAP TLR1 TLR2
3
Show member pathways
13.32 CCL2 CD40LG CXCL12 TIRAP TLR1 TLR2
4
Show member pathways
12.92 CCL2 TIRAP TLR1 TLR2 TLR4 TLR6
5
Show member pathways
12.78 CCL2 TIRAP TLR1 TLR2 TLR4 TLR6
6
Show member pathways
12.59 CD40LG CXCL12 TLR1 TLR2 TLR4 TLR6
7
Show member pathways
12.52 CD40LG TIRAP TLR1 TLR2 TLR4 TLR6
8
Show member pathways
12.43 TIRAP TLR1 TLR2 TLR4 TLR6
9 12.34 CCL2 CD40LG CXCL12 TLR1 TLR2 TLR6
10
Show member pathways
12.2 CD40LG HLA-DQB1 TLR2 TLR4
11 12.09 HLA-DQB1 TLR2 TLR4 TLR6
12
Show member pathways
12.09 TIRAP TLR1 TLR2 TLR4 TLR6
13 12.07 MMP9 TLR1 TLR2 TLR4 TLR6
14
Show member pathways
11.99 TLR1 TLR2 TLR4 TLR6
15
Show member pathways
11.91 TLR1 TLR2 TLR4 TLR6
16 11.89 CCL2 MMP9 TLR4
17
Show member pathways
11.86 TLR1 TLR2 TLR4 TLR6
18 11.85 CCL2 TLR1 TLR2 TLR4 TLR6
19 11.84 CD40LG CXCL12 TIRAP TLR4
20 11.77 TLR1 TLR2 TLR4 TLR6
21 11.65 CD40LG TLR2 TLR4
22 11.54 HSPD1 TLR2 TLR4
23 11.51 CCL2 CXCL12 HLA-DQB1 TLR2 TLR4
24 11.47 CCL2 TLR2 TLR4
25 11.42 HLA-DQB1 HSPD1 TIRAP TLR1 TLR2 TLR4
26 11.4 CCL2 CD40LG TLR2 TLR4
27 11.1 CCL2 CD40LG MMP9 TLR4
28 10.65 CCL2 MMP9 TLR1 TLR2

GO Terms for Pelvic Inflammatory Disease

Cellular components related to Pelvic Inflammatory Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.8 CCL2 CD40LG CHI3L1 CRP CXCL12 HSPD1
2 phagocytic vesicle membrane GO:0030670 9.33 TLR1 TLR2 TLR6
3 lipopolysaccharide receptor complex GO:0046696 8.96 HSPD1 TLR4
4 Toll-like receptor 1-Toll-like receptor 2 protein complex GO:0035354 8.62 TLR1 TLR2

Biological processes related to Pelvic Inflammatory Disease according to GeneCards Suite gene sharing:

(show all 49)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.95 CCL2 CHI3L1 TIRAP TLR4
2 response to lipopolysaccharide GO:0032496 9.95 CCL2 TIRAP TLR2 TLR4
3 immune response GO:0006955 9.92 CCL2 CD40LG CXCL12 HLA-DQB1 TLR1 TLR2
4 positive regulation of gene expression GO:0010628 9.87 CRP TLR2 TLR4
5 defense response to Gram-positive bacterium GO:0050830 9.85 CRP TIRAP TLR2
6 response to mechanical stimulus GO:0009612 9.83 CCL2 CHI3L1 CXCL12
7 positive regulation of interleukin-6 production GO:0032755 9.81 HSPD1 TLR2 TLR4
8 positive regulation of tumor necrosis factor production GO:0032760 9.78 CCL2 TIRAP TLR2 TLR4
9 lipopolysaccharide-mediated signaling pathway GO:0031663 9.77 CCL2 TLR2 TLR4
10 positive regulation of interleukin-8 production GO:0032757 9.73 TIRAP TLR2 TLR4
11 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.73 CD40LG TIRAP TLR2 TLR4
12 activation of NF-kappaB-inducing kinase activity GO:0007250 9.72 CHI3L1 TIRAP TLR6
13 positive regulation of T cell activation GO:0050870 9.71 CCL2 HSPD1
14 toll-like receptor signaling pathway GO:0002224 9.71 TLR1 TLR2 TLR4 TLR6
15 positive regulation of NF-kappaB import into nucleus GO:0042346 9.7 TLR2 TLR4
16 positive regulation of monocyte chemotaxis GO:0090026 9.7 CCL2 CXCL12
17 cell activation GO:0001775 9.7 TLR1 TLR2 TLR6
18 positive regulation of chemokine production GO:0032722 9.69 TLR2 TLR4
19 toll-like receptor 4 signaling pathway GO:0034142 9.69 TIRAP TLR4
20 positive regulation of calcium ion import GO:0090280 9.69 CCL2 CXCL12
21 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.69 CCL2 TLR2 TLR4
22 microglial cell activation GO:0001774 9.68 TLR2 TLR6
23 positive regulation of interferon-alpha production GO:0032727 9.68 HSPD1 TLR4
24 I-kappaB phosphorylation GO:0007252 9.68 TLR2 TLR4
25 T-helper 1 type immune response GO:0042088 9.67 TLR4 TLR6
26 positive regulation of tumor necrosis factor biosynthetic process GO:0042535 9.67 TLR1 TLR4
27 macrophage activation GO:0042116 9.67 TLR1 TLR4
28 cellular response to lipoteichoic acid GO:0071223 9.67 TIRAP TLR2 TLR4
29 positive regulation of interleukin-10 production GO:0032733 9.67 CD40LG HSPD1 TLR2 TLR4
30 interleukin-1 beta secretion GO:0050702 9.66 TLR4 TLR6
31 positive regulation of NLRP3 inflammasome complex assembly GO:1900227 9.64 TLR4 TLR6
32 toll-like receptor TLR6:TLR2 signaling pathway GO:0038124 9.63 TLR2 TLR6
33 positive regulation of interleukin-6 biosynthetic process GO:0045410 9.63 TIRAP TLR1 TLR6
34 cellular response to diacyl bacterial lipopeptide GO:0071726 9.62 TLR2 TLR6
35 cellular response to bacterial lipopeptide GO:0071221 9.62 TIRAP TLR2
36 cellular response to triacyl bacterial lipopeptide GO:0071727 9.61 TLR1 TLR2
37 toll-like receptor TLR1:TLR2 signaling pathway GO:0038123 9.61 TLR1 TLR2
38 inflammatory response GO:0006954 9.61 CCL2 CD40LG CHI3L1 CRP TIRAP TLR1
39 nitric oxide metabolic process GO:0046209 9.6 TLR2 TLR6
40 detection of triacyl bacterial lipopeptide GO:0042495 9.58 TLR1 TLR2
41 detection of diacyl bacterial lipopeptide GO:0042496 9.58 TLR2 TLR6
42 response to bacterial lipoprotein GO:0032493 9.57 TLR2 TLR6
43 regulation of cytokine secretion GO:0050707 9.56 TLR1 TLR2 TLR4 TLR6
44 positive regulation of interleukin-12 production GO:0032735 9.55 CD40LG HSPD1 TIRAP TLR2 TLR4
45 positive regulation of toll-like receptor 2 signaling pathway GO:0034137 9.34 TIRAP
46 positive regulation of macrophage activation GO:0043032 9.24 HSPD1
47 MyD88-dependent toll-like receptor signaling pathway GO:0002755 9.1 HSPD1 TIRAP TLR1 TLR2 TLR4 TLR6
48 signal transduction GO:0007165 10.25 CCL2 CXCL12 TIRAP TLR1 TLR2 TLR4
49 innate immune response GO:0045087 10.06 TIRAP TLR1 TLR2 TLR4 TLR6

Molecular functions related to Pelvic Inflammatory Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 receptor activity GO:0004872 9.62 TLR1 TLR2 TLR4 TLR6
2 protein heterodimerization activity GO:0046982 9.54 TIRAP TLR1 TLR2
3 receptor binding GO:0005102 9.4 CCL2 CXCL12
4 lipopolysaccharide binding GO:0001530 9.33 HSPD1 TLR2 TLR4
5 lipopolysaccharide receptor activity GO:0001875 9.26 TLR2 TLR4
6 lipopeptide binding GO:0071723 9.13 TLR1 TLR2 TLR6
7 Toll-like receptor 2 binding GO:0035663 8.8 TIRAP TLR1 TLR6

Sources for Pelvic Inflammatory Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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