MCID: PLV005
MIFTS: 27

Pelviureteric Junction Obstruction malady

Rare diseases, Nephrological diseases, Fetal diseases, Cancer diseases categories

Aliases & Classifications for Pelviureteric Junction Obstruction

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Sources:
45OMIM, 10diseasecard, 41NIH Rare Diseases, 60UMLS, 47Orphanet, 34MESH via Orphanet, 26ICD10 via Orphanet, 61UMLS via Orphanet, 25ICD10
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Pelviureteric Junction Obstruction, Aliases & Descriptions:

Name: Pelviureteric Junction Obstruction 45 10
Multicystic Renal Dysplasia, Bilateral 45 41 60
Bilateral Multicystic Dysplastic Kidney 41 47
Bilateral Multicystic Renal Dysplasia 41 47
Bilateral Mcdk 41 47
Bilateral Multicystic Dysplastic Kidneys 60
 
Pelvi-Ureteric Junction Obstruction 41
Hydronephrosis Due to Pujo 41
Neoplasm, Residual 60
Pujo 41
Mrd 41


Classifications:



External Ids:

OMIM45 143400
Orphanet47 97364
MESH via Orphanet34 C537373, D021782
ICD10 via Orphanet26 Q61.4
UMLS via Orphanet61 C1567427, C1840451

Summaries for Pelviureteric Junction Obstruction

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MalaCards based summary: Pelviureteric Junction Obstruction, also known as multicystic renal dysplasia, bilateral, is related to multicystic dysplastic kidney and hydronephrosis, and has symptoms including multicystic kidney dysplasia, autosomal dominant inheritance and ureteropelvic junction obstruction. An important gene associated with Pelviureteric Junction Obstruction is HNF1B (HNF1 homeobox B). Affiliated tissues include kidney.

Description from OMIM:45 143400

Related Diseases for Pelviureteric Junction Obstruction

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Diseases related to Pelviureteric Junction Obstruction via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 22)
idRelated DiseaseScoreTop Affiliating Genes
1multicystic dysplastic kidney10.6
2hydronephrosis10.5
3renal dysplasia10.4
4leukemia10.4
5obesity10.4
6mantle cell lymphoma10.4
7nephrolithiasis10.4
8anuria10.4
9polycystic kidney disease10.4
10achalasia10.4
11disseminated intravascular coagulation10.4
12kidney disease10.4
13horseshoe kidney10.4
14gastroschisis10.3
15oligohydramnios10.3
16mayer-rokitansky-kuster-hauser syndrome10.3
17myeloid leukemia10.3
18penile agenesis10.3
19lymphoblastic leukemia10.2
20breast cancer10.0
21wilms tumor10.0
22lymphoblastic lymphoma10.0

Graphical network of the top 20 diseases related to Pelviureteric Junction Obstruction:



Diseases related to pelviureteric junction obstruction

Symptoms for Pelviureteric Junction Obstruction

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Symptoms by clinical synopsis from OMIM:

143400

Clinical features from OMIM:

143400

HPO human phenotypes related to Pelviureteric Junction Obstruction:

(show all 7)
id Description Frequency HPO Source Accession
1 multicystic kidney dysplasia HP:0000003
2 autosomal dominant inheritance HP:0000006
3 ureteropelvic junction obstruction HP:0000074
4 nephrotic syndrome HP:0000100
5 hydronephrosis HP:0000126
6 renal sarcoma HP:0008663
7 congenital megaureter HP:0008676

Drugs & Therapeutics for Pelviureteric Junction Obstruction

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Drug clinical trials:

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Genetic Tests for Pelviureteric Junction Obstruction

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Anatomical Context for Pelviureteric Junction Obstruction

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MalaCards organs/tissues related to Pelviureteric Junction Obstruction:

31
Kidney

Animal Models for Pelviureteric Junction Obstruction or affiliated genes

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Publications for Pelviureteric Junction Obstruction

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Articles related to Pelviureteric Junction Obstruction:

idTitleAuthorsYear
1
Early alteration of urinary exosomal aquaporin 1 and transforming growth factor I^1 after release of unilateral pelviureteral junction obstruction. (22901921)
2012
2
Management of an unusual case of atypical Mayer-Rokitansky-Kuster-Hauser syndrome, with unilateral gonadal agenesis, solitary ectopic pelvic kidney, and pelviureteric junction obstruction. (17093891)
2007
3
Glial cell line-derived neurotrophic factor and synaptophysin expression in pelviureteral junction obstruction. (16461096)
2006
4
Pelviureteral junction obstruction: correlation of renal cell apoptosis and differential renal function. (12771794)
2003
5
Survival in second trimester oligohydramnios secondary to bilateral pelviureteral junction obstruction. (12736042)
2003

Variations for Pelviureteric Junction Obstruction

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Expression for genes affiliated with Pelviureteric Junction Obstruction

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Search GEO for disease gene expression data for Pelviureteric Junction Obstruction.

Pathways for genes affiliated with Pelviureteric Junction Obstruction

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Compounds for genes affiliated with Pelviureteric Junction Obstruction

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GO Terms for genes affiliated with Pelviureteric Junction Obstruction

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Products for genes affiliated with Pelviureteric Junction Obstruction

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Pelviureteric Junction Obstruction

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet