MCID: PMP002
MIFTS: 32

Pemphigoid Gestationis malady

Categories: Rare diseases, Skin diseases

Aliases & Classifications for Pemphigoid Gestationis

About this section
Sources:
45NIH Rare Diseases, 51Orphanet, 65UMLS, 28ICD10 via Orphanet, 37MESH via Orphanet, 66UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Pemphigoid Gestationis:

Name: Pemphigoid Gestationis 45 51 65
Gestational Pemphigoid 45 51
 
Herpes Gestationis 45

Classifications:

Orphanet: 51 
Rare skin diseases


External Ids:

Orphanet51 63275
ICD10 via Orphanet28 L12.8
MESH via Orphanet37 D006559
UMLS via Orphanet66 C0019343

Summaries for Pemphigoid Gestationis

About this section
NIH Rare Diseases:45 Pemphigoid gestationis (pg) is a pregnancy-associated autoimmune skin disorder. it usually begins abruptly during the 2nd or 3rd trimester of pregnancy, but can occur any time during pregnancy. signs and symptoms often include the formation of very itchy, red bumps and/or blisters on the abdomen and trunk, but other parts of the body can be affected. unrelenting itchiness (pruritus) often interferes with daily activities. symptoms may improve at the end of pregnancy, but flares may occur during, or right after, delivery. while it usually goes away on its own within weeks to months after delivery, it may recur during menses; with use of oral contraceptives; and/or with subsequent pregnancies. pg is caused by a woman's immune system mistakenly attacking her own skin, but the exact reasons why this occurs is poorly understood. treatment depends on severity and may include topical corticosteroids; oral corticosteroids, and/or oral antihistamines to relieve itching. last updated: 5/3/2016

MalaCards based summary: Pemphigoid Gestationis, also known as gestational pemphigoid, is related to herpes gestationis and aneurysm, and has symptoms including premature birth, urticaria and erythema/erythematous lesions/erythroderma/polymorphous erythema. An important gene associated with Pemphigoid Gestationis is CCL11 (C-C Motif Chemokine Ligand 11), and among its related pathways is Alpha6-Beta4 Integrin Signaling Pathway. Affiliated tissues include skin, lung and endothelial.

Wikipedia:68 Gestational pemphigoid or pemphigoid gestationis (PG) is a dermatosis of pregnancy, being an autoimmune... more...

Related Diseases for Pemphigoid Gestationis

About this section

Graphical network of the top 20 diseases related to Pemphigoid Gestationis:



Diseases related to pemphigoid gestationis

Symptoms for Pemphigoid Gestationis

About this section

Symptoms:

 51
  • erythema/erythematous lesions/erythroderma/polymorphous erythema
  • prematurity
  • failure to thrive/difficulties for feeding in infancy/growth delay
  • urticaria

HPO human phenotypes related to Pemphigoid Gestationis:

id Description Frequency HPO Source Accession
1 premature birth hallmark (90%) HP:0001622
2 urticaria occasional (7.5%) HP:0001025

Drugs & Therapeutics for Pemphigoid Gestationis

About this section

Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Pemphigoid Gestationis

Genetic Tests for Pemphigoid Gestationis

About this section

Anatomical Context for Pemphigoid Gestationis

About this section

MalaCards organs/tissues related to Pemphigoid Gestationis:

33
Skin, Lung, Endothelial, Brain, Breast, Monocytes, Prostate

Animal Models for Pemphigoid Gestationis or affiliated genes

About this section

Publications for Pemphigoid Gestationis

About this section

Articles related to Pemphigoid Gestationis:

(show top 50)    (show all 107)
idTitleAuthorsYear
1
Human Trypanosomiasis in the Eastern Plains of Colombia: New Transmission Scenario. (26728765)
2016
2
Aligned Nanotopography Promotes a Migratory State in Glioblastoma Multiforme Tumor Cells. (27189099)
2016
3
Functional characterization of the S41Y (C2755A) polymorphism of tryptophan hydroxylase 2. (24899127)
2014
4
Femtosecond lenticule extraction (ReLEx) for correction of hyperopia - first results. (22695934)
2013
5
Non-cardiogenic pulmonary edema and life-threatening shock due to calcium channel blocker overdose and its management: a case report and a clinical review. (23674813)
2013
6
Human annulus cells regulate PAPP-A and IGFBP-4 expression, and thereby insulin-like growth factor bioavailability, in response to proinflammatory cytokine exposure in vitro. (24060054)
2013
7
Evaluation of genetic association between an ITGAM non-synonymous SNP (rs1143679) and multiple autoimmune diseases. (21840425)
2012
8
Mobilization of HIV spread by diaphanous 2 dependent filopodia in infected dendritic cells. (22685410)
2012
9
Interleukin-1 beta-induced up-regulation of opioid receptors in the untreated and morphine-desensitized U87 MG human astrocytoma cells. (23164507)
2012
10
Functional characterization of a genetic polymorphism in the promoter of the ESR2 gene. (21979797)
2012
11
Parathyroid carcinoma with lung metastasis in a thirteen-year-old girl. (22708102)
2012
12
Transforming growth factor beta and platelets in allergic rhinitis and sinusitis. (21967968)
2011
13
Ulnar neuropathy caused by an anconeus epitrochlearis: clinical and electrophysiological findings. (21708839)
2011
14
Evidence-based (S3) guideline for the treatment of androgenetic alopecia in women and in men. (21980982)
2011
15
Prepubertal-type vulva fibroma: a clinicopathological study of two cases]. (20388398)
2010
16
Mechanisms of resistance against PKC412 in resistant FLT3-ITD positive human acute myeloid leukemia cells. (20119833)
2010
17
COX-2-mediated regulation of VEGF-C in association with lymphangiogenesis and lymph node metastasis in lung cancer. (20830783)
2010
18
Prostaglandin E1 for preventing the progression of diabetic kidney disease. (20464745)
2010
19
Traumatic myiasis from Sarcophaga (Bercaeal cruentata Meigen, 1826 (Diptera, Sarcophagidae) in a hospital environment: reporting of a clinical case following polytrauma. (20853677)
2010
20
Migraine with aura induced by artificial microbubbles. (19170691)
2009
21
The DAZL and PABP families: RNA-binding proteins with interrelated roles in translational control in oocytes. (19225045)
2009
22
Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells. (19633668)
2009
23
Topical cyclosporine-A in dry eye associated with chronic graft versus host disease. (20214049)
2009
24
Disruption of neurexin 1 associated with autism spectrum disorder. (18179900)
2008
25
Genetic variation in the schizophrenia-risk gene neuregulin1 correlates with personality traits in healthy individuals. (18455369)
2008
26
Mechanisms of disease: the tissue kallikrein-kinin system in hypertension and vascular remodeling. (17389890)
2007
27
Unilateral limited scleroderma-like changes following formation of an arteriovenous fistula. (17222301)
2007
28
G-CSF and AMD3100 mobilize monocytes into the blood that stimulate angiogenesis in vivo through a paracrine mechanism. (16735597)
2006
29
Gastric MALT lymphoma in the absence of Helicobacter pylori infection presenting as an upper gastrointestinal hemorrhage. (17100037)
2006
30
A case of renal cell carcinoma with multiple lung metastases refractory to interferon-alpha showing complete remission by interleukin-2 monotherapy. (16834666)
2006
31
Cerebellopontine calcification: a new entity of idiopathic intracranial calcification? (15959794)
2005
32
Reduced endocannabinoid immune modulation by a common cannabinoid 2 (CB2) receptor gene polymorphism: possible risk for autoimmune disorders. (15845647)
2005
33
Dent disease with mutations in OCRL1. (15627218)
2005
34
The breast cancer low-penetrance allele 1100delC in the CHEK2 gene is not present in Spanish familial breast cancer population. (14618615)
2004
35
Primaquine induced methemoglobinemia. (12921326)
2003
36
Chromium(VI)-induced damage to the cytoskeleton and cell death in isolated hepatocytes. (12196185)
2002
37
Four new families with autosomal dominant partial epilepsy with auditory features: clinical description and linkage to chromosome 10q24. (11879388)
2002
38
Vaccinia virus F13L protein with a conserved phospholipase catalytic motif induces colocalization of the B5R envelope glycoprotein in post-Golgi vesicles. (11462025)
2001
39
An investigation of the relationship between vitamin B12 deficiency and HIV infection. (10670004)
2000
40
Role of the hypervariable region in streptococcal M proteins: binding of a human complement inhibitor. (9794423)
1998
41
Arylamine N-acetyltransferases. Expression in Escherichia coli, purification, and substrate specificities of recombinant hamster monomorphic and polymorphic isozymes. (8742238)
1996
42
Decreased phospholipase A2 activity in Alzheimer brains. (7893853)
1995
43
Hyperpolarized arrest attenuates myocardial stunning following global surgical ischemia: an alternative to traditional hyperkalemic cardioplegia? (8069046)
1994
44
Clinical usefulness of an assay for hepatitis C virus core in the diagnosis of non-A, non-B hepatitis and monitoring of the response to interferon therapy. (7519894)
1994
45
Evolutionary conserved nucleotides within the E.coli 4.5S RNA are required for association with P48 in vitro and for optimal function in vivo. (1281314)
1992
46
Differential sensitivity of head and neck cancers to non-major histocompatibility-restricted killer cell activity. (2106056)
1990
47
Increases in aspartate aminotransferase and creatine kinase in hemorrhagic shock and encephalopathy syndrome. (2582629)
1989
48
Nonoperative treatment of meconium ileus equivalent. (1190145)
1975
49
50

Variations for Pemphigoid Gestationis

About this section

Expression for genes affiliated with Pemphigoid Gestationis

About this section
Search GEO for disease gene expression data for Pemphigoid Gestationis.

Pathways for genes affiliated with Pemphigoid Gestationis

About this section

Pathways related to Pemphigoid Gestationis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.0COL17A1, DST

GO Terms for genes affiliated with Pemphigoid Gestationis

About this section

Biological processes related to Pemphigoid Gestationis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1immune responseGO:00069559.4CCL11, HLA-DRB1

Sources for Pemphigoid Gestationis

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet