MCID: PMP004
MIFTS: 40

Pemphigus Foliaceus malady

Categories: Rare diseases, Skin diseases

Aliases & Classifications for Pemphigus Foliaceus

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Sources:
32LifeMap Discovery®, 45NIH Rare Diseases, 47Novoseek, 51Orphanet, 65UMLS, 66UMLS via Orphanet, 28ICD10 via Orphanet, 27ICD10
See all MalaCards sources

Aliases & Descriptions for Pemphigus Foliaceus:

Name: Pemphigus Foliaceus 32 45 47 51 65
 
Pf 45

Classifications:

Orphanet: 51 
Rare skin diseases


External Ids:

Orphanet51 79481
UMLS via Orphanet66 C0263313
ICD10 via Orphanet28 L10.2
ICD1027 L10.2
UMLS65 C0263313

Summaries for Pemphigus Foliaceus

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Wikipedia:68 Pemphigus foliaceus is an autoimmune blistering disease of the skin with characteristic lesions that are... more...

MalaCards based summary: Pemphigus Foliaceus, also known as pf, is related to pemphigus and fogo selvagem and pemphigus, and has symptoms including acantholysisand positive nikolski's sign/achantolysis. An important gene associated with Pemphigus Foliaceus is DSG1 (Desmoglein 1), and among its related pathways are Staphylococcus aureus infection and Apoptotic cleavage of cellular proteins. Affiliated tissues include skin, lung and breast.

Related Diseases for Pemphigus Foliaceus

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Graphical network of the top 20 diseases related to Pemphigus Foliaceus:



Diseases related to pemphigus foliaceus

Symptoms for Pemphigus Foliaceus

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Symptoms:

 51
  • positive nikolski's sign/achantolysis

HPO human phenotypes related to Pemphigus Foliaceus:

id Description Frequency HPO Source Accession
1 acantholysis hallmark (90%) HP:0100792

Drugs & Therapeutics for Pemphigus Foliaceus

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Autoimmune Blistering Diseases StudyRecruitingNCT02753777

Search NIH Clinical Center for Pemphigus Foliaceus

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Pemphigus Foliaceus cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Pemphigus Foliaceus:
Hematopoietic stem cells for pemphigus

Genetic Tests for Pemphigus Foliaceus

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Anatomical Context for Pemphigus Foliaceus

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MalaCards organs/tissues related to Pemphigus Foliaceus:

33
Skin, Lung, Breast, Thyroid, Liver, Bone, Neutrophil

Animal Models for Pemphigus Foliaceus or affiliated genes

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Publications for Pemphigus Foliaceus

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Articles related to Pemphigus Foliaceus:

(show top 50)    (show all 536)
idTitleAuthorsYear
1
The Human Umbilical Cord Tissue-Derived MSC Population UCX(Ar) Promotes Early Motogenic Effects on Keratinocytes and Fibroblasts and G-CSF-Mediated Mobilization of BM-MSCs When Transplanted In Vivo. (24480602)
2015
2
Expression of stanniocalcin-1 and stanniocalcin-2 in laryngeal squamous cell carcinoma and correlations with clinical and pathological parameters. (24743310)
2014
3
Recurrent thyroid papillary carcinoma in children under ten years old: report of two cases and literature review. (25214862)
2014
4
On the lack of a clear-cut association between alpha-2-macroglobulin deletion and the risk of Alzheimer disease in Poland. (25574746)
2014
5
Prognostic implications of the magnetic resonance imaging appearance in papillary renal cell carcinoma. (22903703)
2013
6
Self-reported sensory descriptors are associated with quantitative sensory testing parameters in patients with cervical radiculopathy, but not in patients with fibromyalgia. (23108871)
2013
7
Platypnea-orthodeoxia syndrome related to right hemidiaphragmatic elevation and a 'stretched' patent foramen ovale. (23230257)
2012
8
Effects of tobacco smoke on IL-16 in CD8+ cells from human airways and blood: a key role for oxygen free radicals? (21036918)
2011
9
Development of Graves' disease following radioiodine treatment for autonomously functioning thyroid adenoma: case report. (22649896)
2011
10
Calcineurin mediates the angiotensin II-induced aldosterone synthesis in the adrenal glands by up-regulation of transcription of the CYP11B2 gene. (20413672)
2010
11
Randomised, parallel-group, multicentre, multinational phase 2 study comparing edoxaban, an oral factor Xa inhibitor, with warfarin for stroke prevention in patients with atrial fibrillation. (20694273)
2010
12
Estrogen prevents senescence through induction of WRN, Werner syndrome protein. (20395656)
2010
13
Association analysis of the PIP4K2A gene on chromosome 10p12 and schizophrenia in the Irish study of high density schizophrenia families (ISHDSF) and the Irish case-control study of schizophrenia (ICCSS). (19475563)
2010
14
TNFA locus is associated with beta degrees 39 thalassemia in Corsica and Sardinia. (19103526)
2008
15
Ras oncogenes and their downstream targets. (17428555)
2007
16
Laryngeal plasmacytoma presenting as amyloid tumour: a case report. (17431662)
2007
17
BGLAP is expressed in pancreatic cancer cells and increases their growth and invasion. (18163903)
2007
18
The renin-angiotensin system in malignant hypertension revisited: plasma renin activity, microangiopathic hemolysis, and renal failure in malignant hypertension. (17679041)
2007
19
Clinical outcomes in lymphocytopenic lymphatic malformation patients. (18035935)
2007
20
The E-selectin gene polymorphism and carotid atherosclerosis in end-stage renal disease. (16554320)
2006
21
Hypoxia-induced erythropoietin production: a paradigm for oxygen-regulated gene expression. (17002676)
2006
22
Effect of zelandopam, a dopamine D1-like receptor agonist, in puromycin aminonucleoside nephrosis rats. (15740732)
2005
23
Smad expression in human atherosclerotic lesions: evidence for impaired TGF-beta/Smad signaling in smooth muscle cells of fibrofatty lesions. (15166010)
2004
24
Upper and lower eyelid reconstruction for severe disfiguring necrobiotic xanthogranuloma. (15513024)
2004
25
Antitumor activity and other biological actions of oligomers of ribonuclease A. (12697760)
2003
26
Breast tumor resembling the tall cell variant of papillary thyroid carcinoma: report of 5 cases. (12883243)
2003
27
Bilirubin is highly effective in preventing in vivo delta-aminolevulinic acid-induced oxidative cell damage. (12853123)
2003
28
Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice. (12649187)
2003
29
Detection of experimental autoimmune myocarditis in rats by 111In monoclonal antibody specific for tenascin-C. (12221059)
2002
30
Fatal cardiovascular complications in a patient with Ehlers-Danlos syndrome type IV and dextrocardia. (12453701)
2002
31
Antidepressants do not modulate estrogen receptor alpha-mediated gene expression. (11725822)
2001
32
Management of choledocholithiasis found during laparoscopic cholecystectomy: a strategy based on the use of postoperative endoscopic retrograde cholangiography and sphincterotomy. (11332046)
2001
33
Relationship of insulin-like growth factor-I, insulin-like growth factor binding protein-3, insulin, growth hormone in cord blood and maternal factors with birth height and birthweight. (10703231)
2000
34
The promoter of human tissue factor pathway inhibitor gene: identification of potential regulatory elements. (10515290)
1999
35
Malignant nodular hidradenoma of nose. (23119494)
1999
36
MUC1 (episialin) expression in non-small cell lung cancer is independent of EGFR and c-erbB-2 expression and correlates with poor survival in node positive patients. (9930070)
1998
37
Clonality analysis of hematopoiesis and thrombopoietin levels in patients with essential thrombocythemia. (9669688)
1998
38
Increased expression of platelet-derived growth factor A and collagenous matrix proteins in congenital multicystic renal dysplasia. (9200407)
1997
39
Neutrophil-activating protein ENA-78 and IL-8 exhibit different patterns of expression in lipopolysaccharide- and cytokine-stimulated human monocytes. (9103458)
1997
40
Spinal epidural abscess in hemodialysis patients: report of three cases and review of the literature. (8546141)
1996
41
Properties of TAN-67, a nonpeptidic delta-opioid receptor agonist, at cloned human delta- and mu-opioid receptors. (8566162)
1995
42
Determination of the activity of delta-aminolevulinic acid dehydratase--a method for the diagnosis of lead poisoning in birds]. (7940512)
1994
43
Activation of IL-6 production by UV irradiation of blood mononuclear cells from patients with systemic lupus erythematosus. (1638768)
1992
44
Differential effects of inhibitors of cellular function on inflammatory mediator-stimulated increases in vascular permeability. (1726113)
1991
45
Antiepileptic drugs, hepatic enzyme induction and raised serum alkaline phosphatase isoenzymes. (1983078)
1990
46
The RII subunit of cAMP-dependent protein kinase binds to a common amino-terminal domain in microtubule-associated proteins 2A, 2B, and 2C. (2561973)
1989
47
Osteochondrosis in feedlot cattle. (7257092)
1981
48
49
50

Variations for Pemphigus Foliaceus

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Expression for genes affiliated with Pemphigus Foliaceus

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Search GEO for disease gene expression data for Pemphigus Foliaceus.

Pathways for genes affiliated with Pemphigus Foliaceus

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GO Terms for genes affiliated with Pemphigus Foliaceus

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Cellular components related to Pemphigus Foliaceus according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cell-cell junctionGO:00059119.7DSG1, DSG2
2plasma membraneGO:00058868.4DSG1, DSG2, DSG3, PPL

Biological processes related to Pemphigus Foliaceus according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1response to progesteroneGO:00325709.9DSG1, DSG2
2homophilic cell adhesion via plasma membrane adhesion moleculesGO:00071569.4DSG2, DSG3
3apoptotic processGO:00069158.8DSG1, DSG2, DSG3

Sources for Pemphigus Foliaceus

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet