MCID: PMP005
MIFTS: 52

Pemphigus Vulgaris malady

Categories: Genetic diseases, Rare diseases, Skin diseases

Aliases & Classifications for Pemphigus Vulgaris

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Sources:
32LifeMap Discovery®, 45NIH Rare Diseases, 47Novoseek, 51Orphanet, 65UMLS, 28ICD10 via Orphanet, 66UMLS via Orphanet, 27ICD10
See all MalaCards sources

Aliases & Descriptions for Pemphigus Vulgaris:

Name: Pemphigus Vulgaris 32 45 47 51 65

Characteristics:

Orphanet epidemiological data:

51
pemphigus vulgaris:
Inheritance: Not applicable; Prevalence: 1-5/10000 (Europe); Age of onset: Adult

Classifications:

Orphanet: 51 
Rare skin diseases


External Ids:

Orphanet51 704
ICD10 via Orphanet28 L10.0
UMLS via Orphanet66 C0030809
ICD1027 L10.0
UMLS65 C0030809

Summaries for Pemphigus Vulgaris

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NIH Rare Diseases:45 Pemphigus vulgaris is an autoimmune disorder that involves blistering of the skin and mucous membranes. it occurs almost exclusively in middle-aged or older people. many cases begin with blisters in the mouth, followed by skin blisters that may come and go. in most cases, the exact cause of pemphigus vulgaris is unknown. it has rarely been observed in multiple members of the same family. treatment is aimed at reducing symptoms and preventing complications. severe cases are treated similarly to severe burns. last updated: 3/16/2010

MalaCards based summary: Pemphigus Vulgaris is related to familial pemphigus vulgaris and pemphigus, and has symptoms including abnormal scarring/cheloids/hypertrophic scars, urticaria and vesicles/bullous/exsudative lesions/bullous/cutaneous/mucosal detachment. An important gene associated with Pemphigus Vulgaris is DSG3 (Desmoglein 3), and among its related pathways are Cell adhesion_Endothelial cell contacts by junctional mechanisms and Antiarrhythmic Pathway, Pharmacodynamics. Affiliated tissues include skin, t cells and thyroid, and related mouse phenotypes are adipose tissue and integument.

Wikipedia:68 Pemphigus vulgaris is a chronic blistering skin disease with skin lesions that may initially be... more...

Related Diseases for Pemphigus Vulgaris

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Diseases in the Pemphigus Vulgaris family:

Familial Pemphigus Vulgaris

Diseases related to Pemphigus Vulgaris via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 146)
idRelated DiseaseScoreTop Affiliating Genes
1familial pemphigus vulgaris12.5
2pemphigus11.6
3pemphigus foliaceus10.8
4pemphigus vegetans10.7
5intellectual disability-sparse hair-brachydactyly syndrome10.5DSG1, DSG3
6acute opioid poisoning10.4DSG1, DSG3
7pili gemini10.4DSG3, DSP
8bullous pemphigoid10.4
9paraneoplastic pemphigus10.4
10braddock syndrome10.3DSG1, DSP
11dermatitis herpetiformis10.3DSG1, DSG4
12dilated cardiomyopathy with woolly hair, keratoderma, and tooth agenesis10.3DSP, JUP
13microcystic lymphatic malformation10.3DSC3, DSG1
14arrhythmogenic right ventricular dysplasia 810.3DSP, JUP
15esophagitis10.3
16pemphigus erythematosus10.3
17hypercholesterolemia, familial10.2DSP, JUP
18pancreatic intraductal papillary-mucinous adenoma10.2DSG1, DSP
19arrhythmogenic right ventricular dysplasia 1210.2DSP, JUP
20gingivitis10.2
21thyroiditis10.2
22lichen planus10.2
23mucous membrane pemphigoid10.2
24pervasive developmental disorder10.1DSG1, DSP
25paronychia10.1
26endometrial disease10.1DSG1, DSG3, JUP
27small intestine lymphoma10.1DSG1, DSG3, DSG4
28sarcoma10.1
29cicatricial pemphigoid10.1
30herpes simplex10.1
31psoriasis10.1
32hay-wells syndrome10.1DSP, JUP
33juvenile dermatitis herpetiformis10.0DSG1, DSP
34pemphigus vulgaris10.0DSG1, DSG2, DSG3
35bartholin's duct cyst10.0DSC3, DSG1, DSG3
36rheumatoid arthritis10.0
37arthritis10.0
38nocardiosis10.0
39thymoma10.0
40folliculitis10.0
41periodontitis10.0
42lupus erythematosus10.0
43oral lichen planus10.0
44tufted hair folliculitis10.0
45pylorus cancer10.0CDH1, JUP
46inappropriate adh syndrome10.0DSG1, DSP, JUP
47skin squamous cell carcinoma10.0DSG1, DSG2
48alopecia9.9
49hematopoietic stem cell transplantation9.9
50keloids9.9

Graphical network of the top 20 diseases related to Pemphigus Vulgaris:



Diseases related to pemphigus vulgaris

Symptoms for Pemphigus Vulgaris

About this section

Symptoms:

 51 (show all 10)
  • abnormal scarring/cheloids/hypertrophic scars
  • urticaria
  • vesicles/bullous/exsudative lesions/bullous/cutaneous/mucosal detachment
  • positive nikolski's sign/achantolysis
  • furuncle/cutaneous abscess/hidrosadenitis suppurativa
  • enanthema/aphtosa/aphta/leukoplakia
  • feeding disorder/dysphagia/swallowing/sucking disorder/esophageal dyskinesia
  • immunodeficiency/increased susceptibility to infections/recurrent infections
  • autoimmunity/autoimmune reaction/autoantibodies
  • weight loss/loss of appetite/break in weight curve/general health alteration

Drugs & Therapeutics for Pemphigus Vulgaris

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Drugs for Pemphigus Vulgaris (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 58)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Mycophenolic acidapprovedPhase 389824280-93-1446541
Synonyms:
(e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
Acide mycophenolique
Acido micofenolico
Acidum mycophenolicum
Melbex
 
Micofenolico acido
Mycophenoic acid
Mycophenolate
Mycophenolic Acid
Mycophenolsaeure
Myfortic
2
MethylprednisoloneapprovedPhase 3, Phase 2108283-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
A-methapred
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Depo-medrol
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Solu-medrol
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
3
PrednisoloneapprovedPhase 3, Phase 2108250-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
Flo-pred
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
MLS001304083
 
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
Millipred
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Omnipred
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
4
Mycophenolate mofetilapproved, investigationalPhase 3898128794-94-55281078
Synonyms:
115007-34-6
128794-94-5
140401-05-4
2-Morpholinoethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (e)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-morpholin-4-ylethyl (4E)-6-[4-hydroxy-7-methyl-6-(methyloxy)-3-oxo-1,3-dihydro-2-benzofuran-5-yl]-4-methylhex-4-enoate
2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl -3-oxo-5-isobenzofuranyl)-4-methyl-, 2-(4-morpholinyl)ethyl ester, (4E)
AC-1562
AC1NQXZW
AC1Q6O6X
AR-1J6939
BB_NC-2566
C07908
C23H31NO7
CHEMBL1456
CID5281078
CellCept
CellCept, RS 61443, TM-MMF, Mycophenolate mofetil
Cellcept
Cellcept (TN)
D00752
DB00688
HMS2090A03
 
HSDB 7436
I01-0898
I06-1947
LS-172272
LS-75572
ME-MPA
MMF
MMF CellCept(TM)
MolPort-000-883-800
Munoloc
Mycophenolate Mofetil
Mycophenolate mofetil (JAN/USAN)
Mycophenolic acid morpholinoethyl ester
Mycophenylate mofetil
NCGC00159459-02
NCGC00159459-03
NSC724229
R-99
RS 61443
RS-61443
RS-61443-190
S1501_Selleck
TL8000648
TM-MMF
UNII-9242ECW6R0
ZINC21297660
mycophenolate mofetil
5
PrednisoneapprovedPhase 3, Phase 2, Phase 0126753-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
Juvason
 
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Perrigo Prednisone
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rayos
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
6
rituximabapprovedPhase 31582174722-31-710201696
Synonyms:
AntiCD20
IDEC-102
IDEC-C2B8
 
Ig gamma-1 chain C region
MabThera
Mabthera
Rituxan
rituximab
7Methylprednisolone HemisuccinatePhase 3, Phase 21082
8Methylprednisolone acetatePhase 3, Phase 21082
9Immunologic FactorsPhase 3, Phase 2, Phase 018483
10Peripheral Nervous System AgentsPhase 3, Phase 218510
11Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 3, Phase 29988
12Prednisolone acetatePhase 3, Phase 21082
13Anti-Bacterial AgentsPhase 3, Phase 2, Phase 09140
14Prednisolone phosphatePhase 3, Phase 21082
15Prednisolone hemisuccinatePhase 3, Phase 21082
16HormonesPhase 3, Phase 211748
17Antibiotics, AntitubercularPhase 3, Phase 05971
18Hormone AntagonistsPhase 3, Phase 210002
19ImmunoglobulinsPhase 3, Phase 24477
20Antibodies, MonoclonalPhase 3, Phase 22413
21AntibodiesPhase 3, Phase 24477
22Antirheumatic AgentsPhase 3, Phase 28496
23Immunosuppressive AgentsPhase 3, Phase 2, Phase 010422
24AnalgesicsPhase 3, Phase 29358
25glucocorticoidsPhase 3, Phase 23896
26Analgesics, Non-NarcoticPhase 3, Phase 25184
27Gastrointestinal AgentsPhase 3, Phase 26401
28Antineoplastic Agents, HormonalPhase 3, Phase 24256
29Anti-Inflammatory AgentsPhase 3, Phase 28478
30
AzathioprineapprovedPhase 2153446-86-62265
Synonyms:
446-86-6
55774-33-9 (hydrochloride salt)
6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine
6-((1-Methyl-4-nitroimidazol-5-yl)thio)purine
6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine
6-(1'-Methyl-4'-nitro-5'-imidazolyl)mercaptopurine
6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine
6-(1-Methyl-4-nitroimidazol-5-ylthio)purin
6-(1-Methyl-4-nitroimidazol-5-ylthio)purin [Czech]
6-(1-Methyl-p-nitro-5-imidazolyl)-thiopurine
6-(1-Methyl-p-nitro-5-imidazolyl)thiopurine
6-(3-Methyl-5-nitro-3H-imidazol-4-ylsulfanyl)-7H-purine
6-(3-methyl-5-nitroimidazol-4-yl)sulfanyl-7H-purine
6-(Methyl-p-nitro-5-imidazolyl)-thiopurine
6-(Methyl-p-nitro-5-imidazolyl)thiopurine
6-({4-nitro-1-methyl-1H-imidazol-5-yl}sulfanyl)-7H-purine
6-1'-Methyl,4'-nitro,5'-imidazolyl mercaptopurine
6-[(1-Methyl-4-nitroimidazol-5-yl)- thio] purine
6-[(1-Methyl-4-nitroimidazol-5-yl)thio]purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-Purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-7H-purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-9H-purine
A 4638
A2593_SIAL
A4638_SIAL
A4638_SIGMA
AB00443544
AB00443544-03
AC-4230
AC1L1DAL
AC1Q3Z1F
AI-981/34845012
AI3-50290
Azamun
Azamun [Czech]
Azanin
Azasan
Azasan (TN)
Azasan, Imuran, Azamun, BW-57-322, NSC-39084, Azathioprine
Azathioprin
Azathioprine
Azathioprine (JP15/USP/INN)
Azathioprine Sodium
Azathioprine [USAN:INN:BAN:JAN]
Azathioprine sodium
Azathioprinum
Azathioprinum [INN-Latin]
Azathiopurine
Azatioprin
Azatioprina
Azatioprina [INN-Spanish]
Azothioprine
B. W. 57-322
BPBio1_000054
BRD-K32821942-001-05-6
BRD-K60324116-001-01-5
BSPBio_000048
BSPBio_001876
BW 57-322
BW 57322
BW-57-322
C06837
C9H7N7O2S
CAS-446-86-6
CBDivE_013132
CCRIS 62
CHEBI:2948
CHEMBL1542
CID2265
CPD000427366
Ccucol
ChemDiv1_002659
Cytostatics
D00238
DB00993
DivK1c_000586
EINECS 207-175-4
EU-0100027
FT-0083532
HMS1568C10
 
HMS1920E17
HMS2091K19
HMS501N08
HMS594I19
HSDB 7084
IDI1_000586
Immuran
Imuran
Imuran (TN)
Imuran (tn)
Imurek
Imurel
KBio1_000586
KBio2_000464
KBio2_002427
KBio2_003032
KBio2_004995
KBio2_005600
KBio2_007563
KBio3_001376
KBio3_002906
KBioGR_000646
KBioGR_002427
KBioSS_000464
KBioSS_002433
LS-123
Lopac-A-4638
Lopac0_000027
MLS001049307
Methylnitroimidazolylmercaptopurine
MolPort-000-745-914
MolPort-000-764-262
MolPort-003-665-485
Muran
NCGC00015060-01
NCGC00015060-02
NCGC00015060-04
NCGC00015060-12
NCGC00090836-01
NCGC00090836-02
NCGC00090836-03
NCGC00090836-04
NCGC00090836-05
NCGC00090836-06
NCGC00094593-01
NCGC00094593-02
NCGC00094593-03
NCI-C03474
NINDS_000586
NSC 39084
NSC-39084
NSC39084
Oprea1_375441
Oprea1_533384
Oprea1_633462
Prestwick0_000094
Prestwick1_000094
Prestwick2_000094
Prestwick3_000094
Prestwick_41
S1721_Selleck
SAM002589938
SDCCGMLS-0065415.P001
SMR000427366
SPBio_000255
SPBio_001987
SPECTRUM1500133
STK831906
STOCK1S-20293
STOCK1S-27186
Spectrum2_000068
Spectrum3_000308
Spectrum4_000243
Spectrum5_000848
Spectrum_000064
Thiopurine 6-(1-methyl-4-nitroimidazol-5-yl)
UNII-MRK240IY2L
WLN: T56 BM DN FN HNJ IS- ET5N CNJ A1 DNW
ZINC04258316
[Methyl(nitroimidazolyl)mercaptopurine]
azathioprine
azatiopr in
cMAP_000046
31
InfliximabapprovedPhase 2349170277-31-3
Synonyms:
Ig gamma-1 chain C region
 
Inflectra
Remicade
Remsima
32
Etanerceptapproved, investigationalPhase 2383185243-69-0
Synonyms:
185243-69-0
CD120b
D00742
Enbrel
Enbrel (TN)
Enbrel Sureclick
Etanercept
Etanercept (USAN/INN)
 
Etanercept (genetical recombination)
Etanercept (genetical recombination) (JAN)
TNF-R2
Tumor necrosis factor receptor 2
Tumor necrosis factor receptor superfamily member 1B precursor
Tumor necrosis factor receptor type II
etanercept
p75
p80 TNF-alpha receptor
33
Dapsoneapproved, investigationalPhase 26280-08-02955
Synonyms:
(4-sulfanilylphenyl)amine
1,1'-Sulfonylbis(4-aminobenzene)
1,1'-Sulfonylbis[4-aminobenzene]
1,1'-Sulphonylbis(4-aminobenzene)
1358F
32960_FLUKA
4,4' Diaminophenyl Sulfone
4,4'-Dapsone
4,4'-Diaminodiphenyl sulfone
4,4'-Diaminodiphenyl sulphone
4,4'-Diaminodiphenyl suphone
4,4'-Diaminodiphenylsulfone
4,4'-Sulfonylbisaniline
4,4'-Sulfonylbisbenzamine
4,4'-Sulfonylbisbenzenamine
4,4'-Sulfonylbisbenzeneamine
4,4'-Sulfonyldianilin
4,4'-Sulfonyldianiline
4,4'-Sulfonyldianiline (Dapsone)
4,4'-Sulphonylbisbenzamine
4,4'-Sulphonylbisbenzenamine
4,4'-Sulphonyldianiline
4,4'-diaminophenyl sulfone
4,4'-sulfonyldianiline
4,4-Diaminodifenylsulfon
4,4-Diaminodifenylsulfon [Czech]
4,4-Sulfonyldianiline
4-(4-Aminophenylsulfonyl)aniline
4-(4-Aminophenylsulfonyl)benzenamine
4-(4-amino-Benzenesulfonyl)-phenylamine
4-(4-aminophenyl)sulfonylaniline
4-Aminop henyl sulfone
4-Aminophenyl sulfone
4-Aminophenylsulfone
4-[(4-aminobenzene)sulfonyl]aniline
4-[(4-aminophenyl)sulfonyl]aniline
46158_FLUKA
46158_RIEDEL
80-08-0
A74807_ALDRICH
AB00051962
AB1004833
AC-10922
AC1L1EUH
AC1Q51WM
AC1Q51WN
AI3-08087
AKOS000119322
ALBB-005917
AZT + Dapsone cominbation
Acedapsone
Aczone
Aczone (TN)
Ambap80-08-0
Araldite HT
Araldite HT 976
Araldite Ht
Atrisone
Avlosulfon
Avlosulfone
Avlosulphone
Avsulfor
BIDD:GT0770
BPBio1_000143
BRD-K62363391-001-05-8
BRN 0788055
BSPBio_000129
BSPBio_002129
Bis(4-aminophenyl) sulfone
Bis(4-aminophenyl)sulfone
Bis(4-aminophenyl)sulphone
Bis(P-aminophenyl) sulfone
Bis(p-aminophenyl) sulfone
Bis(p-aminophenyl)sulphone
C07666
CAS-80-08-0
CBDivE_013582
CCRIS 192
CHEBI:4325
CHEMBL1043
CID2955
CPD000059064
Croysulfone
Croysulphone
D SS
D003622
D00592
D0089
DADPS
DAPSONE
DB00250
DDS
DDS (pharmaceutical)
DDS, diaphenylsulfone
DDS, pharmaceutical
DIAPHENYLSULFONE
DSS
DSS (VAN)
Dapsoderm-X
Dapson
Dapson-Fatol
Dapsona
Dapsona [INN-Spanish]
Dapsone
Dapsone (USP)
Dapsone [USAN:BAN]
Dapsonum
Dapsonum [INN-Latin]
Dds, Diaphenylsulfone
Dds, Pharmaceutical
Di(4-aminophenyl) sulfone
Di(4-aminophenyl)sulfone
Di(4-aminophenyl)sulphone
Di(p-aminophenyl) sulfone
Di(p-aminophenyl)sulphone
Diamino-4,4'-diphenyl sulfone
Diamino-4,4'-diphenyl sulphone
Diamino-diphenyl sulphone
Diaminodifenilsulfona
Diaminodifenilsulfona [Spanish]
Diaminodiphenyl Sulfone
Diaminodiphenyl sulfone
Diaminodiphenylsulfone
Diaphenylsulfon
 
Diaphenylsulfone
Diaphenylsulfone (JAN)
Diaphenylsulphon
Diaphenylsulphone
Dimitone
Diphenasone
Diphone
Disulone
DivK1c_000573
Dubronax
Dubronaz
Dumitone
EINECS 201-248-4
Eporal
F 1358
Fatol Brand of Dapsone
HMS1568G11
HMS1920C14
HMS2091K04
HMS501M15
HSDB 5073
HT 976
HY 976
Hardener HT 976
I01-3640
ICI
IDI1_000573
IN-201
KBio1_000573
KBio2_001368
KBio2_003936
KBio2_006504
KBio3_001349
KBioGR_000900
KBioSS_001368
LS-1790
MLS000069409
MLS001055349
MLS001076146
Metabolite C
Mex-America Brand of Dapsone
MolPort-001-780-172
N, N'-Diphenyl Sulfondiamide
N, N'-Diphenyl sulfondiamide
N,N'-Diphenyl sulfondiamide
NCGC00016322-01
NCGC00016322-02
NCGC00023946-03
NCGC00023946-04
NCGC00023946-05
NCGC00023946-06
NCI-C01718
NINDS_000573
NSC 6091
NSC 6091D
NSC-6091
NSC6091
Normet
Novophone
Oprea1_143052
Orsade Brand of Dapsone
P, P'-Sulfonyldianiline
P,P'-Diaminodiphenyl Sulfone
P,P'-diaminodiphenyl sulfone
P,P-Diaminodiphenyl Sulphone
P,P-Sulfonylbisbenzamine
P,P-Sulfonylbisbenzenamine
P,P-Sulphonylbisbenzamine
P,P-Sulphonylbisbenzenamine
P,P-Sulphonyldianiline
P-Aminophenyl Sulfone
P-Aminophenyl sulfone
Prestwick0_000035
Prestwick1_000035
Prestwick2_000035
Prestwick3_000035
Prestwick_152
Protogen
Recolip
SAM002554879
SMR000059064
SPBio_001025
SPBio_002050
SPECTRUM1500222
STK387118
Spectrum2_001133
Spectrum3_000375
Spectrum4_000310
Spectrum5_000825
Spectrum_000888
Sulfadione
Sulfanona-Mae
Sulfanona-mae
Sulfon-Mere
Sulfon-mere
Sulfona
Sulfona-MAE
Sulfona-Mae
Sulfone Ucb
Sulfone ucb
Sulfone, 4,4'-Diaminophenyl
Sulfonyldianiline
Sulphadione
Sulphon-Mere
Sulphon-mere
Sulphonyldianiline
Sumicure S
TL8005401
Tarimyl
UNII-8W5C518302
Udolac
W R 448
WLN: ZR DSWR DZ
WR 448
ZINC00006310
dapsone
p, p'-Sulfonyldianiline
p,p'-Diaminodiphenyl sulfone
p,p'-sulfonyldianiline
p,p-Diaminodiphenyl sulphone
p,p-Sulfonylbisbenzamine
p,p-Sulfonylbisbenzenamine
p,p-Sulphonylbisbenzamine
p,p-Sulphonylbisbenzenamine
p,p-Sulphonyldianiline
p-Aminophenyl sulfone
34
Cyclophosphamideapproved, investigationalPhase 2264350-18-0, 6055-19-22907
Synonyms:
(+-)-Cyclophosphamide
(-)-Cyclophosphamide
(RS)-Cyclophosphamide
1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine
1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin
2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
4-Hydroxy-cyclophosphan-mamophosphatide
50-18-0
60007-95-6
6055-19-2 (monohydrate)
75526-90-8
AC1L1EQQ
AI3-26198
ASTA
ASTA B518
Asta B 518
B 518
B-518
BRN 0011744
BSPBio_002099
Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
C 0768
C07888
C7H15Cl2N2O2P
CB 4564
CB-4564
CCRIS 188
CHEBI:4027
CHEMBL32520
CHEMBL88
CID2907
CP
CPA
CTX
CY
Ciclofosfamida
Ciclofosfamida [INN-Spanish]
Ciclofosfamide
Ciclophosphamide
Ciclophosphamide [INN]
Clafen
Claphene
Cycloblastin
Cyclophosphamid
Cyclophosphamide
Cyclophosphamide (INN)
Cyclophosphamide (TN)
Cyclophosphamide (anhydrous form)
Cyclophosphamide (anhydrous)
Cyclophosphamide Monohydrate
Cyclophosphamide Sterile
Cyclophosphamide anhydrous
Cyclophosphamide, (+-)-Isomer
Cyclophosphamides
Cyclophosphamidum
Cyclophosphamidum [INN-Latin]
Cyclophosphan
Cyclophosphane
Cyclophosphanum
Cyclophosphoramide
Cyclostin
Cyklofosfamid
Cyklofosfamid [Czech]
Cytophosphan
Cytophosphane
Cytoxan
Cytoxan (TN)
Cytoxan Lyoph
D,L-Cyclophosphamide
D07760
DB00531
 
DivK1c_000246
EINECS 200-015-4
EU-0100238
Endoxan
Endoxan R
Endoxan-Asta
Endoxana
Endoxanal
Endoxane
Enduxan
Genoxal
HMS2090A12
HSDB 3047
Hexadrin
IDI1_000246
KBio1_000246
KBio2_001338
KBio2_003906
KBio2_006474
KBio3_001319
KBioGR_000888
KBioSS_001338
LS-1302
LS-99787
Ledoxina
Lopac-C-0768
Lopac0_000238
Lyophilized Cytoxan
Mitoxan
MolPort-001-783-420
N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
NCGC00015209-01
NCGC00015209-03
NCGC00015209-06
NCGC00091741-02
NCGC00091741-03
NCI-C04900
NCI60_002097
NINDS_000246
NSC 26271
NSC-26271
NSC26271
NSC273033
NSC273034
Neosar
Occupation, cyclophosphamide exposure
Procytox
RCRA waste no. U058
Rcra Waste Number U058
Rcra waste number U058
Revimmune
S1217_Selleck
SK 20501
SPBio_001071
STK177249
STOCK2S-91217
Semdoxan
Sendoxan
Senduxan
Spectrum2_001146
Spectrum3_000370
Spectrum4_000304
Spectrum5_000795
Spectrum_000858
UNII-6UXW23996M
WLN: T6MPOTJ BO BN2G2G
Zyklophosphamid
Zyklophosphamid [German]
bis(2-Chloroethyl)phosphami de cyclic propanolamide
bis(2-Chloroethyl)phosphamide cyclic propanolamide ester
cyclophosphamide
35
Folic Acidapproved, nutraceuticalPhase 2292459-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic Acid
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
 
Folsaeure
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
36AntimetabolitesPhase 29454
37Adjuvants, ImmunologicPhase 21783
38Antimetabolites, AntineoplasticPhase 25770
39Anti-Inflammatory Agents, Non-SteroidalPhase 23549
40Dermatologic AgentsPhase 24555
41Alkylating AgentsPhase 23582
42Immunoglobulins, IntravenousPhase 2211
43Rho(D) Immune GlobulinPhase 2206
44Vitamin B ComplexPhase 22847
45Antineoplastic Agents, AlkylatingPhase 23406
46Folic Acid AntagonistsPhase 21643
47Antiparasitic AgentsPhase 21854
48Anti-Infective AgentsPhase 2, Phase 017220
49Antiprotozoal AgentsPhase 21730
50AntimalarialsPhase 21058

Interventional clinical trials:

(show all 15)
idNameStatusNCT IDPhase
1A Study to Assess the Effect of CellCept (Mycophenolate Mofetil) and Reduced Corticosteroids in Patients With Active Pemphigus Vulgaris (PV)CompletedNCT00683930Phase 3
2A Randomized, Double-Blind Study to Evaluate the Efficacy and Safety of Rituximab Versus MMF in Patients With Pemphigus VulgarisRecruitingNCT02383589Phase 3
3Efficacy and Safety of Ofatumumab in Treatment of Pemphigus VulgarisTerminatedNCT01920477Phase 3
4Long-Term Extension Study of Ofatumumab in Subjects With Pemphigus VulgarisWithdrawnNCT02613910Phase 3
5Study of Etanercept (Enbrel) in the Treatment of Pemphigus VulgarisCompletedNCT00135720Phase 2
6Azathioprine Versus Placebo in Pemphigus Vulgaris Treated With PrednisoloneCompletedNCT00626678Phase 2
7Use of KC706 for the Treatment of Pemphigus VulgarisCompletedNCT00606749Phase 2
8Use of Infliximab for the Treatment of Pemphigus VulgarisCompletedNCT00283712Phase 2
9A Study of PRN1008 in Adult Patients With Pemphigus VulgarisRecruitingNCT02704429Phase 2
10Study of Efficacy and Safety of VAY736 in Patients With Pemphigus VulgarisActive, not recruitingNCT01930175Phase 2
11Efficacy of Dapsone as a Steroid Sparing Agent in Pemphigus VulgarisTerminatedNCT00429533Phase 2
12Randomized Trial of IVIg With or Without Cyclophosphamide in PemphigusTerminatedNCT00483119Phase 2
13Safety Study of PI-0824 to Treat Pemphigus VulgarisCompletedNCT00063752Phase 1
14Autoimmune Blistering Diseases StudyRecruitingNCT02753777
15Evaluating Sirolimus to Treat Autoimmune Blistering Dermatosis PemphigusTerminatedNCT01313923Phase 0

Search NIH Clinical Center for Pemphigus Vulgaris

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Pemphigus Vulgaris cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Pemphigus Vulgaris:
Hematopoietic stem cells for pemphigus

Genetic Tests for Pemphigus Vulgaris

About this section

Anatomical Context for Pemphigus Vulgaris

About this section

MalaCards organs/tissues related to Pemphigus Vulgaris:

33
Skin, T cells, Thyroid, Heart, B cells, Lung, Prostate

Animal Models for Pemphigus Vulgaris or affiliated genes

About this section

MGI Mouse Phenotypes related to Pemphigus Vulgaris:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053758.9DSG1, DSG3, DSG4, JUP
2MP:00107717.6CDH1, DSC3, DSG3, DSG4, DSP, JUP
3MP:00107687.0CDH1, DSC3, DSG2, DSG3, DSG4, DSP

Publications for Pemphigus Vulgaris

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Articles related to Pemphigus Vulgaris:

(show top 50)    (show all 834)
idTitleAuthorsYear
1
Detection of IgG antibodies to desmoglein 3 and desmocollins 2 and 3 in mucosal dominant-type pemphigus vulgaris with severe pharyngalgia and hyperemia of the bulbar conjunctiva. (26463887)
2015
2
Therapeutic Plasma Exchange-A New Dawn in the Treatment of Pemphigus Vulgaris. (26288426)
2015
3
Paradoxical Worsening of Pemphigus Vulgaris Following Rituximab Therapy. (25832868)
2015
4
Prognostic factors in pemphigus vulgaris and pemphigus foliaceus. (24102444)
2013
5
Laboratory diagnosis of herpesvirus infections in patients with Pemphigus vulgaris lesions. (23735576)
2013
6
Direct immunofluorescence of the outer root sheath in anagen and telogen hair in pemphigus vulgaris and pemphigus foliaceus. (23713982)
2013
7
Neural nitric oxide synthase participates in pemphigus vulgaris acantholysis through upregulation of Rous sarcoma, mammalian target of rapamycin and focal adhesion kinase. (23362871)
2013
8
An unusual epiglottis synechiae managed with transoral robotic surgery in a patient with pemphigus vulgaris. (24036806)
2013
9
Signaling dependent and independent mechanisms in pemphigus vulgaris blister formation. (23226536)
2012
10
Aberrant epigenetic modifications in peripheral blood mononuclear cells from patients with pemphigus vulgaris. (22512277)
2012
11
Pathogenic relevance of IgG and IgM antibodies against desmoglein 3 in blister formation in pemphigus vulgaris. (21718682)
2011
12
Acute zoster in known pemphigus vulgaris and bullous pemphigoid: avoiding the "disease flare" trap. (21571161)
2011
13
HLA-DRB1*04:02, DRB1*08:04 and DRB1*14 alleles associated to pemphigus vulgaris in southeastern Brazilian population. (21554253)
2011
14
Pemphigus vulgaris antigen mRNA quantification for the staging of sentinel lymph nodes in head and neck cancer. (19997107)
2010
15
The efficacy of nicotinamide gel 4% as an adjuvant therapy in the treatment of cutaneous erosions of pemphigus vulgaris. (20597951)
2010
16
ABO blood groups and pemphigus vulgaris: no relationship. (20372776)
2010
17
Binding of pemphigus vulgaris IgG to antigens in desmosome core domains excludes immune complexes rather than directly splitting desmosomes. (20222919)
2010
18
Desquamative esophagitis due to pemphigus vulgaris. (21086254)
2010
19
Targeted immunotherapy with rituximab leads to a transient alteration of the IgG autoantibody profile in pemphigus vulgaris. (20671975)
2010
20
Autoimmunity to desmocollin 3 in pemphigus vulgaris. (20952584)
2010
21
An imbalance in Akt/mTOR is involved in the apoptotic and acantholytic processes in a mouse model of pemphigus vulgaris. (19552768)
2009
22
Loss of the desmosomal protein perp enhances the phenotypic effects of pemphigus vulgaris autoantibodies. (19158843)
2009
23
Prevalence of non-organ-specific autoantibodies in patients with pemphigus vulgaris. (19298776)
2009
24
Cleavage of desmoglein 3 can explain its depletion from keratinocytes in pemphigus vulgaris. (18505410)
2008
25
CD4+CD25high regulatory T cells are markedly decreased in blood of patients with pemphigus vulgaris. (17377382)
2007
26
Treatment of refractory pemphigus vulgaris with anti-CD20 monoclonal antibody (rituximab): five cases. (17538808)
2007
27
Rituximab therapy in severe juvenile pemphigus vulgaris. (18038698)
2007
28
Synergistic actions of pemphigus vulgaris IgG, Fas-ligand and tumor necrosis factor-alpha during induction of basal cell shrinkage and acantholysis. (17101499)
2006
29
Preliminary data on Pemphigus vulgaris treatment by a proteomics-defined peptide: a case report. (17062151)
2006
30
Mucosal dominant pemphigus vulgaris with anti-desmoplakin autoantibodies. (15243525)
2004
31
Association between HLA-DRB1, DQB1 genes and pemphigus vulgaris in Chinese Hans]. (12579512)
2003
32
Treatment of pemphigus vulgaris and pemphigus foliaceus with mycophenolate mofetil. (12810504)
2003
33
Tufted hair folliculitis associated with pemphigus vulgaris. (12705759)
2003
34
Paraneoplastic pemphigus with circulating antibodies directed exclusively against the pemphigus vulgaris antigen desmoglein 3. (11004638)
2000
35
Analysis of the T cells that are potentially involved in autoantibody production in pemphigus vulgaris. (10635617)
1999
36
Anti-intercellular substance antibody log titres are correlated with serum concentrations of interleukin-6, interleukin-15 and tumor necrosis factor-alpha in patients with Pemphigus vulgaris relationships with peripheral blood neutrophil counts, disease severity and duration and patients' age. (10703946)
1999
37
Antibodies against desmoglein 3 (pemphigus vulgaris antigen) are present in sera from patients with paraneoplastic pemphigus and cause acantholysis in vivo in neonatal mice. (9710446)
1998
38
Mucosal and mucocutaneous (generalized) pemphigus vulgaris show distinct autoantibody profiles. (9326396)
1997
39
Herpetiform pemphigus showing reactivity with pemphigus vulgaris antigen (desmoglein 3) (9274636)
1997
40
Cloning of the gene for human pemphigus vulgaris antigen (desmoglein 3), a desmosomal cadherin. Characterization of the promoter region and identification of a keratinocyte-specific cis-element. (8663392)
1996
41
Paronychia--a manifestation of pemphigus vulgaris. (8959911)
1996
42
Pemphigus foliaceus and pemphigus vulgaris autoantibodies react with the extracellular domain of desmoglein-1. (7860995)
1995
43
Granulocyte activation in bullous diseases: release of granular proteins in bullous pemphigoid and pemphigus vulgaris. (8393016)
1993
44
Ultrastructural binding site of pemphigus foliaceus autoantibodies: comparison with pemphigus vulgaris. (1918503)
1991
45
Sequence analysis of the HLA-DR beta and HLA-DQ beta loci from three Pemphigus vulgaris patients. (3391803)
1988
46
A newly characterized HLA DQ beta allele associated with pemphigus vulgaris. (2894075)
1988
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Variations for Pemphigus Vulgaris

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Expression for genes affiliated with Pemphigus Vulgaris

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Search GEO for disease gene expression data for Pemphigus Vulgaris.

Pathways for genes affiliated with Pemphigus Vulgaris

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GO Terms for genes affiliated with Pemphigus Vulgaris

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Cellular components related to Pemphigus Vulgaris according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intercalated discGO:00147049.8DSG2, JUP
2cell-cell adherens junctionGO:00059139.7CDH1, JUP
3lateral plasma membraneGO:00163289.7CDH1, JUP
4cell-cell junctionGO:00059119.2DSG1, DSG2, JUP
5plasma membraneGO:00058867.4DSC3, DSG1, DSG2, DSG3, DSG4, DSP

Biological processes related to Pemphigus Vulgaris according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1regulation of ventricular cardiac muscle cell action potentialGO:009891110.1DSP, JUP
2response to progesteroneGO:00325709.9DSG1, DSG2
3regulation of heart rate by cardiac conductionGO:00860919.9DSG2, DSP
4cellular response to indole-3-methanolGO:00716819.7CDH1, JUP
5homophilic cell adhesion via plasma membrane adhesion moleculesGO:00071569.3DSG2, DSG3, DSG4
6single organismal cell-cell adhesionGO:00163378.9DSG1, DSG4, DSP, JUP
7adherens junction organizationGO:00343328.9CDH1, DSP, JUP
8apoptotic processGO:00069157.7CDH1, DSG1, DSG2, DSG3, DSP

Sources for Pemphigus Vulgaris

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet