Aliases & Classifications for Periapical Granuloma

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Aliases & Descriptions for Periapical Granuloma:

Name: Periapical Granuloma 11 13 48 37 66
 
Apical Granuloma 11

Classifications:



External Ids:

Disease Ontology11 DOID:4617
SNOMED-CT60 196344002, 81407003
MeSH37 D010484

Summaries for Periapical Granuloma

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MalaCards based summary: Periapical Granuloma, also known as apical granuloma, is related to spinal cord lipoma and transvestism, and has symptoms including mass of digestive structure An important gene associated with Periapical Granuloma is TNFSF11 (Tumor Necrosis Factor Superfamily Member 11), and among its related pathways are NF-kappa B signaling pathway and EBV LMP1 signaling. Affiliated tissues include endothelial, neutrophil and t cells, and related mouse phenotypes are immune system and hematopoietic system.

Related Diseases for Periapical Granuloma

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Diseases related to Periapical Granuloma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 44)
idRelated DiseaseScoreTop Affiliating Genes
1spinal cord lipoma10.2CP, HP
2transvestism10.2CP, HP
3ivic syndrome10.2CP, HP
4urinary bladder posterior wall cancer10.2CP, HP
5breast adenomyoepithelioma10.2CP, HP
6atransferrinemia10.2CP, HP
7benign fibrous mesothelioma10.0CXCL8, TNFSF11
8lymphangioma10.0CXCL8, TNFSF11
9pleomorphic lipoma9.9CXCL8, TNFSF11
10subglottis neoplasm9.9CXCL8, HP
11eosinophilic gastroenteritis9.9CXCL8, TNFSF11
12malignant giant cell tumor9.9CXCL8, TNFSF11
13mongolian spot9.9CXCL8, HP
14kidney angiomyolipoma9.9CXCL8, HP
15xanthomatosis9.9CXCL8, TNFSF11
16leprosy9.9
17lepromatous leprosy9.9
18endotheliitis9.9
19diphtheria9.9CP, CXCL8
20gonadal disease9.8CCL5, CXCL8
21asbestosis9.8CP, CXCL8
22orbital plasma cell granuloma9.8CCL5, CXCL8
23orbital lymphangioma9.8CCL5, CXCL8
24palmoplantar keratosis9.8CXCL8, TNFSF11
25malakoplakia9.8CCL5, CXCL8
26dentin caries9.8CCL5, CXCL8
27iridocyclitis9.8CCL5, CXCL8
28inner ear disease9.7CCL5, CXCL8
29chronic rhinitis9.7CXCL8, TNFSF11
30blind hypotensive eye9.7CCL5, CXCL8
31geniculate herpes zoster9.7CCL5, CXCL8
32motion sickness9.7CCL5, CXCL8
33benign renovascular hypertension9.6CCL5, CXCL8
34laryngeal tuberculosis9.6CCL5, CXCL8
35gingivitis9.6CCL5, CXCL8
36basaloid squamous cell carcinoma9.5CCL5, CXCL8
37gemistocytic astrocytoma9.4CCL5, CXCL8, TNFSF11
38cervix carcinoma9.4CCL5, CXCL8
39fundus dystrophy9.4CCL5, CXCL8
40chronic endophthalmitis9.3CCL5, CP, CXCL8
41hyperpigmentation of eyelid9.3CCL5, CXCL8, HP
42rheumatoid arthritis8.9CCL5, CXCL8, TNFSF11
43malaria8.6CCL5, CXCL8, HP
44hydranencephaly8.0CCL5, CDH5, CP, CXCL8, HP, TNFSF11

Graphical network of the top 20 diseases related to Periapical Granuloma:



Diseases related to periapical granuloma

Symptoms for Periapical Granuloma

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UMLS symptoms related to Periapical Granuloma:


mass of digestive structure

Drugs & Therapeutics for Periapical Granuloma

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Interventional clinical trials:

idNameStatusNCT IDPhase
1RCT: Effectiveness of a Microscope During Dental Root Apical SurgeryRecruitingNCT01759069

Search NIH Clinical Center for Periapical Granuloma


Cochrane evidence based reviews: periapical granuloma

Genetic Tests for Periapical Granuloma

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Anatomical Context for Periapical Granuloma

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MalaCards organs/tissues related to Periapical Granuloma:

34
Endothelial, Neutrophil, T cells, Monocytes, Colon, Bone

Animal Models for Periapical Granuloma or affiliated genes

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MGI Mouse Phenotypes related to Periapical Granuloma:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053878.3CCL5, CDH5, CP, HP, TNFSF11
2MP:00053978.1CCL5, CDH5, CP, HP, TNFSF11

Publications for Periapical Granuloma

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Articles related to Periapical Granuloma:

(show all 35)
idTitleAuthorsYear
1
Bioinformatics, Interaction Network Analysis, and Neural Networks to Characterize Gene Expression of Radicular Cyst and Periapical Granuloma. (25873079)
2015
2
Expression and immunohistochemical localization of leptin receptor in human periapical granuloma. (25081278)
2014
3
Heparanase expression in periapical granulomas and radicular cysts. (22020734)
2013
4
Oral pathology quiz #81. Case number 4. Dental (periapical) granuloma. (24597181)
2013
5
Periapical granuloma associated with extracted teeth. (22037071)
2011
6
Midkine expression in human periapical granulomas. (21787488)
2011
7
T-helper cell type 17/regulatory T-cell immunoregulatory balance in human radicular cysts and periapical granulomas. (20478453)
2010
8
Distinct Th1, Th2 and Treg cytokines balance in chronic periapical granulomas and radicular cysts. (20102461)
2010
9
High matrix metalloproteinase activity is a hallmark of periapical granulomas. (19720222)
2009
10
Antrochoanal polyp derived from periapical granuloma. (18701055)
2008
11
Differential patterns of receptor activator of nuclear factor kappa B ligand/osteoprotegerin expression in human periapical granulomas: possible association with progressive or stable nature of the lesions. (18634923)
2008
12
Involvement of inducible nitric oxide synthase and receptor for advanced glycation end products in periapical granulomas. (17258631)
2007
13
RANKL in human periapical granuloma: possible involvement in periapical bone destruction. (16700737)
2006
14
Co-production of vascular endothelial cadherin and inducible nitric oxide synthase by endothelial cells in periapical granuloma. (16507070)
2006
15
Oral diagnosis. Interradicular radiolucency of maxilla. Periapical granuloma. (16161239)
2005
16
Intraneural epithelial islands associated with a periapical granuloma: a cause for concern? (12796887)
2003
17
Hydrogen peroxide and superoxide anion production by polymorphonuclear neutrophils in patients with chronic periapical granuloma, before and after surgical treatment. (11355101)
2001
18
Evaluation of immunoglobulin G synthesizing plasma cells in periapical granuloma and cyst. (11441800)
2001
19
The presence of chemokine receptor (CCR5, CXCR3, CCR3)-positive cells and chemokine (MCP1, MIP-1alpha, MIP-1beta, IP-10)-positive cells in human periapical granulomas. (11683586)
2001
20
Differential in situ distribution of interleukin-8, monocyte chemoattractant protein-1 and Rantes in human chronic periapical granuloma. (11155167)
2000
21
Cytotoxic T lymphocytes versus streptococcal colonization in periapical granulomas. (10425947)
1999
22
Focal cemento-osseous dysplasia in the maxilla mimicking periapical granuloma. (10442950)
1999
23
Interferon-gamma-producing cells and inducible nitric oxide synthase-producing cells in periapical granulomas. (9563799)
1998
24
Immune cells in periapical granuloma: morphological and immunohistochemical characterization. (1895036)
1991
25
Quantitative analysis of the immunocompetent cells in periapical granuloma: correlation with the histological characteristics of the lesions. (1974913)
1990
26
The role of acute phase proteins in the pathogenesis of chronic periapical granuloma]. (1698164)
1990
27
Acute phase proteins in patients with chronic periapical granuloma before and after surgical treatment. (3268759)
1988
28
Endodontic treatment and immunopathology of periapical granuloma in an AIDS patient. (2977755)
1988
29
In situ characterization of cells in periapical granuloma by monoclonal antibodies. (3477750)
1987
30
Bacteriological status of periapical granuloma. (6597195)
1984
31
Macrophages isolated from periapical granuloma: a scanning electron microscopic study. (6592531)
1984
32
Isolation and characterization of inflammatory cells from the human periapical granuloma. (6983538)
1982
33
Quantitative analysis of cellular composition of human periapical granuloma. (6938631)
1981
34
Reddening of the upper central incisors associated with periapical granuloma in lepromatous leprosy. (1063039)
1976
35
A colony of actinomyces-like organisms in a periapical granuloma. (4161341)
1966

Variations for Periapical Granuloma

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Expression for genes affiliated with Periapical Granuloma

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Search GEO for disease gene expression data for Periapical Granuloma.

Pathways for genes affiliated with Periapical Granuloma

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GO Terms for genes affiliated with Periapical Granuloma

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Cellular components related to Periapical Granuloma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056157.6CCL5, CP, CXCL8, HP, TNFSF11
2extracellular regionGO:00055767.3CCL5, CP, CXCL8, HP, TNFSF11

Biological processes related to Periapical Granuloma according to GeneCards Suite gene sharing:

(show all 12)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of homotypic cell-cell adhesionGO:003411210.0CCL5, TNFSF11
2positive regulation of osteoclast differentiationGO:00456729.9CCL5, TNFSF11
3monocyte chemotaxisGO:00025489.9CCL5, TNFSF11
4positive regulation of phosphorylationGO:00423279.4CCL5, TNFSF11
5negative regulation of G-protein coupled receptor protein signaling pathwayGO:00457449.4CCL5, CXCL8
6neutrophil activationGO:00421199.3CCL5, CXCL8
7cellular response to interleukin-1GO:00713479.3CCL5, CXCL8
8cellular response to tumor necrosis factorGO:00713569.3CCL5, CXCL8
9neutrophil chemotaxisGO:00305939.2CCL5, CXCL8
10positive regulation of angiogenesisGO:00457669.1CCL5, CXCL8
11chemokine-mediated signaling pathwayGO:00700988.9CCL5, CXCL8
12cellular response to fibroblast growth factor stimulusGO:00443448.7CCL5, CXCL8

Molecular functions related to Periapical Granuloma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1chemokine activityGO:00080099.0CCL5, CXCL8

Sources for Periapical Granuloma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet