MCID: PRC012
MIFTS: 52

Pericardial Effusion

Categories: Cardiovascular diseases

Aliases & Classifications for Pericardial Effusion

MalaCards integrated aliases for Pericardial Effusion:

Name: Pericardial Effusion 12 28 51 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:118
MeSH 41 D010490
NCIt 46 C3319
SNOMED-CT 64 373945007 70370001
ICD10 32 I31.3
UMLS 69 C0031039

Summaries for Pericardial Effusion

Disease Ontology : 12 A pericardium disease that is characterized by an abnormal accumulation of fluid in the pericardial cavity.

MalaCards based summary : Pericardial Effusion is related to cardiac tamponade and constrictive pericarditis. An important gene associated with Pericardial Effusion is ADA (Adenosine Deaminase), and among its related pathways/superpathways are Kaposi's sarcoma-associated herpesvirus infection and MicroRNAs in cardiomyocyte hypertrophy. The drugs Colchicine and Diclofenac have been mentioned in the context of this disorder. Affiliated tissues include lung, heart and myeloid, and related phenotypes are cardiovascular system and homeostasis/metabolism

Related Diseases for Pericardial Effusion

Diseases in the Pericardial Effusion family:

Pericardial Effusion, Chronic

Diseases related to Pericardial Effusion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 328)
# Related Disease Score Top Affiliating Genes
1 cardiac tamponade 31.5 ACVRL1 NPPB PVR REN
2 constrictive pericarditis 30.8 ADA NPPB
3 pericarditis 30.3 ADA CRP IL6 NPPB TNFRSF1A
4 peritonitis 30.2 ADA CRP IL6
5 metabolic encephalomyopathic crises, recurrent, with rhabdomyolysis, cardiac arrhythmias, and neurodegeneration 30.2 CHKB PIK3C2A
6 inferior myocardial infarction 30.1 NPPB PIK3C2A
7 endocarditis 30.1 CRP IL6 PIK3C2A
8 neutrophilia, hereditary 30.1 CRP IL6
9 meningitis 30.1 ADA CRP IL6
10 pneumonia 29.9 CRP IL6 PIK3C2A
11 castleman disease 29.8 CRP IL6
12 kawasaki disease 29.7 CRP IL6 NPPB
13 mitral valve stenosis 29.5 ACVRL1 NPPA NPPB
14 chronic kidney failure 29.5 CRP IL6 NPPB REN
15 tetralogy of fallot 29.5 NPPA NPPB REN VEGFA
16 esophageal cancer 29.3 CRP HIF1A IL6 VEGFA
17 cardiac rupture 29.2 CHKB CRP
18 acute myocardial infarction 29.1 CHKB CRP NPPA NPPB PIK3C2A
19 dilated cardiomyopathy 28.8 CHKB CRP IL6 NPPA NPPB REN
20 heart disease 28.8 CRP IL6 NPPA NPPB PIK3C2A REN
21 pulmonary hypertension 28.4 ACVRL1 HIF1A IL6 NPPA NPPB REN
22 myocardial infarction 28.2 CHKB CRP HIF1A IL6 NPPA NPPB
23 pericardial effusion, chronic 12.4
24 hemopericardium 12.2
25 cantu syndrome 11.4
26 lymphedema, hereditary, iii 11.3
27 camptodactyly-arthropathy-coxa vara-pericarditis syndrome 11.1
28 dressler's syndrome 11.1
29 pericardial tuberculosis 11.1
30 vibrio vulnificus infection 10.5 IL6 PIK3C2A
31 chronic angina 10.5 NPPB REN
32 critical limb ischemia 10.4 IL6 VEGFA
33 cold agglutinin disease 10.4 CRP IL6
34 chronic thromboembolic pulmonary hypertension 10.4 CRP NPPB
35 diabetic foot ulcers 10.4 CRP IL6
36 acute adrenal insufficiency 10.4 IL6 REN
37 cryopyrin-associated periodic syndrome 10.4 CRP IL6
38 miliary tuberculosis 10.4 ADA CRP
39 acute cholangitis 10.4 CRP IL6
40 hypoaldosteronism 10.4 NPPA REN
41 postural hypotension 10.3 NPPA REN
42 renal artery disease 10.3 NPPA REN
43 intravascular papillary endothelial hyperplasia 10.3 HIF1A VEGFA
44 spinal disease 10.3 CRP IL6 VEGFA
45 tuberculous meningitis 10.3 ADA NPPA VEGFA
46 creatine phosphokinase, elevated serum 10.3 CHKB PIK3C2A
47 peripheral artery disease 10.3 CRP IL6 VEGFA
48 intermittent claudication 10.3 CRP IL6 VEGFA
49 viral meningitis 10.3 ADA CRP IL6
50 hypothyroidism 10.3

Graphical network of the top 20 diseases related to Pericardial Effusion:



Diseases related to Pericardial Effusion

Symptoms & Phenotypes for Pericardial Effusion

MGI Mouse Phenotypes related to Pericardial Effusion:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.21 REN TNFRSF1A VEGFA PIK3C2A NPPA CRP
2 homeostasis/metabolism MP:0005376 10.18 PIK3C2A REN TNFRSF1A VEGFA IL6 ADA
3 behavior/neurological MP:0005386 10.16 PIK3C2A REN TNFRSF1A VEGFA IL6 CHKB
4 hematopoietic system MP:0005397 10.1 PIK3C2A REN TNFRSF1A VEGFA IL6 ADA
5 muscle MP:0005369 10 REN TNFRSF1A VEGFA CHKB NPPA FGF2
6 liver/biliary system MP:0005370 9.87 TNFRSF1A VEGFA ADA IL6 ACADVL HIF1A
7 neoplasm MP:0002006 9.63 TNFRSF1A VEGFA IL6 FGF2 ACADVL HIF1A
8 nervous system MP:0003631 9.61 VEGFA PIK3C2A REN TNFRSF1A IL6 CHKB
9 renal/urinary system MP:0005367 9.28 REN TNFRSF1A VEGFA PIK3C2A IL6 ADA

Drugs & Therapeutics for Pericardial Effusion

Drugs for Pericardial Effusion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 124)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Colchicine Approved Phase 4,Phase 3 64-86-8 2833 6167
2
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
3
Citric Acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
4 Antirheumatic Agents Phase 4,Phase 3,Phase 2
5 Antimitotic Agents Phase 4,Phase 3,Phase 2,Phase 1
6 Analgesics Phase 4
7 Analgesics, Non-Narcotic Phase 4
8 Anti-Inflammatory Agents Phase 4,Phase 3
9 Anti-Inflammatory Agents, Non-Steroidal Phase 4
10 Cyclooxygenase Inhibitors Phase 4
11 Peripheral Nervous System Agents Phase 4,Phase 3
12 Phosphodiesterase 5 Inhibitors Phase 4
13 Phosphodiesterase Inhibitors Phase 4
14 Sildenafil Citrate Phase 4 171599-83-0
15 Vasodilator Agents Phase 4
16 Citrate Nutraceutical Phase 4
17
Bleomycin Approved, Investigational Phase 3 11056-06-7 5360373
18
Methylprednisolone Approved, Vet_approved Phase 3 83-43-2 6741
19
Prednisolone Approved, Vet_approved Phase 3 50-24-8 5755
20
Cyclophosphamide Approved, Investigational Phase 2, Phase 3 50-18-0, 6055-19-2 2907
21
Mesna Approved, Investigational Phase 2, Phase 3 3375-50-6 598
22
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 10339178 38904 498142
23
Paclitaxel Approved, Vet_approved Phase 3,Phase 2,Phase 1 33069-62-4 36314
24
Dasatinib Approved, Investigational Phase 3,Phase 1,Phase 2 302962-49-8 3062316
25
Prednisone Approved, Vet_approved Phase 3 53-03-2 5865
26
Docetaxel Approved May 1996, Investigational Phase 3,Phase 2 114977-28-5 148124 9877265
27 Immunosuppressive Agents Phase 2, Phase 3,Phase 1
28 Anti-Bacterial Agents Phase 3,Phase 1,Phase 2
29 Antibiotics, Antitubercular Phase 3,Phase 1,Phase 2
30 Antiemetics Phase 3
31 Antineoplastic Agents, Hormonal Phase 3
32 Autonomic Agents Phase 3
33 Gastrointestinal Agents Phase 3
34 glucocorticoids Phase 3
35 Hormone Antagonists Phase 3
36 Hormones Phase 3
37 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3
38 Methylprednisolone acetate Phase 3
39 Methylprednisolone Hemisuccinate Phase 3
40 Neuroprotective Agents Phase 3
41 Prednisolone acetate Phase 3
42 Prednisolone hemisuccinate Phase 3
43 Prednisolone phosphate Phase 3
44 Protective Agents Phase 3
45 Vaccines Phase 3
46 Alkylating Agents Phase 2, Phase 3
47 Antilymphocyte Serum Phase 2, Phase 3
48 Albumin-Bound Paclitaxel Phase 3,Phase 2,Phase 1
49 Antineoplastic Agents, Phytogenic Phase 3,Phase 2,Phase 1
50 Protein Kinase Inhibitors Phase 3,Phase 1,Phase 2

Interventional clinical trials:

(show top 50) (show all 72)

# Name Status NCT ID Phase Drugs
1 Non Steroidal Anti Inflammatory Treatment for Post Operative Pericardial Effusion Completed NCT00247052 Phase 4 diclofenac;diclofenac;matching placebo
2 Cochicine Treatment for Post- Operative Pericardial Effusion Completed NCT01266694 Phase 4 Colchicines;Placebo
3 Impact of Colchicine Therapy on Arrhythmia Recurrence After Acute Pericardial Effusion Recruiting NCT02260206 Phase 4 Colchicine
4 The Effect of Chest Tubes Using Active Clearance Technology® on the Incidence of Postoperative Atrial Fibrillation Recruiting NCT02808897 Phase 4
5 Safety And Efficacy Of Sildenafil In Children With Pulmonary Arterial Hypertension Active, not recruiting NCT01642407 Phase 4 Sildenafil
6 Safety, Tolerability, Pharmacokinetics and Efficacy of Two Different Rates of Subcutanous Remodulin® Dose Titration in Pulmonary Arterial Hypertension Withdrawn NCT02893995 Phase 4 Slow Dose Titration Group of Subcutaneous Treprostinil;Rapid Dose Titration Group of Subcutaneous Treprostinil
7 COlchicine for Prevention of the Post-pericardiotomy Syndrome and Post-operative Atrial Fibrillation (COPPS-2 Trial) Unknown status NCT01552187 Phase 3 Colchicine;Placebo
8 Trial of Drainage With or Without Bleomycin Instillation for Malignant Pericardial Effusion Completed NCT00132613 Phase 3 Pericardial instillation of bleomycin after drainage
9 A Trial of Adjunctive Prednisolone and Mycobacterium w Immunotherapy in Tuberculous Pericarditis Completed NCT00810849 Phase 3 Prednisolone
10 Scleroderma: Cyclophosphamide or Transplantation (SCOT) Completed NCT00114530 Phase 2, Phase 3 cyclophosphamide
11 Study of NOV-002 in Combination With Chemotherapy to Treat Lung Cancer Completed NCT00347412 Phase 3 Paclitaxel and Carboplatin;NOV-002 Injection in combination with Carboplatin vs. Paclitaxel and Carboplatin
12 Randomized Study Comparing Docetaxel Plus Dasatinib to Docetaxel Plus Placebo in Castration-resistant Prostate Cancer Completed NCT00744497 Phase 3 Placebo;Dasatinib;Docetaxel;Prednisone
13 IMPI 2 - A Trial of Intrapericardial Alteplase in Large Pericardial Effusion Recruiting NCT02673879 Phase 3
14 NGR-hTNF in Combination With Standard Chemotherapy to Treat Patients With Advanced Non-small Cell Lung Cancer Unknown status NCT00994097 Phase 2 NGR-hTNF;Cisplatin;Gemcitabine;Pemetrexed
15 ILX-295501 in Treating Patients With Stage III or Stage IV Ovarian Cancer That Has Not Responded to Previous Treatment Unknown status NCT00005645 Phase 2 ILX-295501
16 Combined CABG and Stem-Cell Transplantation for Heart Failure Unknown status NCT00418418 Phase 2
17 Phase I/II Safety Study of IPI-504 in Relapsed/Refractory Stage IIIb, or Stage IV Non-small Cell Lung Cancer (NSCLC) Completed NCT00431015 Phase 1, Phase 2 IPI-504
18 Dasatinib (Sprycel™) in Patients With Newly Diagnosed Core Binding Factor (CBF) Acute Myeloid Leukemia (AML) Completed NCT00850382 Phase 1, Phase 2 Dasatinib;daunorubicin;Cytarabine
19 A Study of Bevacizumab Plus Carboplatin and Paclitaxel in Subjects With Advanced, Previously Untreated, Squamous Non-Small Cell Lung Cancer (BRIDGE) Completed NCT00318136 Phase 2 Bevacizumab;Carboplatin;Paclitaxel
20 Triplet Combination First Line Treatment in Non Small Cell Lung Cancer (NSCLC) Completed NCT00942825 Phase 2 CBP501 + Cisplatin + Pemetrexed;Cisplatin + Pemetrexed
21 Phase II Study of Cetuximab in Combination With Carboplatin and Docetaxel for Patients With Advanced Non-Small Cell Lung Cancer Completed NCT00251498 Phase 2 Cetuximab
22 Safety and Efficacy Evaluation of Two Year Imatinib Treatment in Adjuvant Gastrointestinal Stromal Tumor (GIST) Completed NCT01172548 Phase 2 imatinib mesylate
23 QUILT-2.013: A Trial of AMG 479 or AMG 102 in Combination With Platinum-based Chemotherapy as First-Line Treatment for Extensive Stage Small Cell Lung Cancer Completed NCT00791154 Phase 1, Phase 2 AMG 479;Etoposide;Placebo;AMG 102;Carboplatin;Cisplatin
24 Single Agent Alimta in Poor Performance Status in Non-small Cell Lung Cancer Completed NCT00508144 Phase 2 Alimta
25 The Effects Of Fx-1006A On Transthyretin Stabilization And Clinical Outcome Measures In Patients With V122I Or Wild-Type TTR Amyloid Cardiomyopathy Completed NCT00694161 Phase 2 Fx-1006A
26 Erlotinib Hydrochloride With or Without Carboplatin and Paclitaxel in Treating Patients With Stage III-IV Non-small Cell Lung Cancer Active, not recruiting NCT00126581 Phase 2 Carboplatin;Erlotinib Hydrochloride;Paclitaxel
27 Intrapleural Bevacizumab Injection for Malignant Effusion in Lung Cancer Enrolling by invitation NCT02054052 Phase 2 Bevacizumab
28 Bioprosthetic or Native Aortic Scallop Intentional Laceration to Prevent Iatrogenic Coronary Artery Obstruction (BASILICA) Prospective Investigation Not yet recruiting NCT03381989 Phase 1, Phase 2
29 Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/Neu Completed NCT00004074 Phase 1
30 Trastuzumab Plus R115777 in Treating Patients With Advanced or Metastatic Cancer Completed NCT00005842 Phase 1 tipifarnib
31 Pericardiocentesis With Magnetic Resonance Imaging Terminated NCT01479569 Phase 1
32 Drainage or Pericardiocentesis (DROP) Alone for Recurrent Non-malignant Pericardial Effusions Requiring Intervention Unknown status NCT01665495
33 Prevention of Retained-Blood Outcomes With Active Clearance Technology Unknown status NCT02145858
34 Contact Force Sensing and Pulmonary Vein Isolation Unknown status NCT01630031
35 Pleural and Pericardial Effusion Following Open Heart Surgery Completed NCT02045641
36 Evaluation of Different Strategies of Pericardial Drainage After Aortic Valvular Surgery Completed NCT00684125
37 Screening of Patients Admitted to a Local Hospital With Pocket-sized Ultrasound Completed NCT01081210
38 BRIPPED Scan for Evaluation of Emergency Department (ED) Patients With Shortness of Breath Completed NCT01662843
39 Medical Need of OAC Reversal Completed NCT03254147 warfarin;dabigatran;Apixaban;Edoxaban;Rivaroxaban
40 Influence of Routinely Adding Ultrasound Screening in Medical Department Completed NCT01331187
41 Single-operator Ultrasound-guided IV Placement by Emergency Nurses Completed NCT01439113
42 "EASE" Epicardial Access With the EpiAccess System Completed NCT02209064
43 A Study of Strategies for Electrical Isolation of Pulmonic Veins for Curative Treatment of Atrial Fibrillation Completed NCT00434694
44 Validation of Epworth Richmond's Echocardiography Education Focused Year Completed NCT02961439
45 Establishment of Patient Derived Cancer Cell Models to Interrogate Novel Molecular Targets in Metastatic Cancer Recruiting NCT02646228
46 Prehospital Use of Ultrasound in Undifferentiated Shortness of Breath Recruiting NCT02638649
47 Improvement of the Etiological Diagnosis of the Pericarditis Recruiting NCT02828085
48 Canadian Left Atrial Appendage Closure Study Recruiting NCT03133806
49 Active Clearance Technology (ACT) II German Multicenter Trial Recruiting NCT02479737
50 Detection of (Sub)Clinical Toxicity in Irradiated vs. Non-irradiated Surgically Treated Esophageal Cancer Patients: a Pilot Study (CROSS SECT) Recruiting NCT03396614

Search NIH Clinical Center for Pericardial Effusion

Genetic Tests for Pericardial Effusion

Genetic tests related to Pericardial Effusion:

# Genetic test Affiliating Genes
1 Pericardial Effusion 28

Anatomical Context for Pericardial Effusion

MalaCards organs/tissues related to Pericardial Effusion:

38
Lung, Heart, Myeloid, Prostate, Liver, Kidney, Breast

Publications for Pericardial Effusion

Articles related to Pericardial Effusion:

(show top 50) (show all 745)
# Title Authors Year
1
Pericardial effusion following cardiac surgery. A single-center experience. ( 29171276 )
2018
2
Non-operative management is feasible for selected blunt trauma patients with pericardial effusion. ( 29191668 )
2018
3
Possible involvement of IL-6-producing tissue-resident macrophages in early-onset pericardial effusion pathogenesis after hematopoietic stem cell transplantation. ( 29384263 )
2018
4
PCR evaluation of selected vector-borne pathogens in dogs with pericardial effusion. ( 29355984 )
2018
5
Relevant pericardial effusion caused by cytomegalovirus infection in an immunocompetent patient: a case report. ( 29347961 )
2018
6
Atypical Presentation of a Large Pericardial Effusion after Heart Transplantation in a Patient with Dilated Cardiomyopathy. ( 29429930 )
2018
7
Cough as the sole manifestation of pericardial effusion. ( 29437733 )
2018
8
Pericardial effusion unrelated to surgery is a predictor of mortality in heart transplant patients. ( 29341061 )
2018
9
Pleural and pericardial effusion in a long-term PD patient - a defying diagnosisa8c. ( 29231161 )
2018
10
Corrigendum to "Prenatal Diagnosis of Cardiac Diverticulum with Pericardial Effusion in the First Trimester of Pregnancy with Resolution after Early Pericardiocentesis". ( 28811945 )
2017
11
Pericardial Effusion: A Rare Side Effect of TNF-Alpha Blocking Agent. ( 28742729 )
2017
12
Automatic detection of hemorrhagic pericardial effusion on PMCT using deep learning - a feasibility study. ( 28819715 )
2017
13
Focal intramural pericardial effusion and cardiac tamponade associated with necrotic adipose tissue in a dog. ( 28671499 )
2017
14
Hemorrhagic pericardial effusion as the debut of acquired hemophilia in a chronic lymphocytic leukemia patient: A case report, and a review of acquired hemophilia A-related hematological malignancies. ( 29381944 )
2017
15
Long-Term Outcomes after Video-Assisted Thoracoscopic Pericardiectomy for Pericardial Effusion. ( 28794388 )
2017
16
The Echocardiographic Characteristics and Prognostic Significance of Pericardial Effusions in Eisenmenger Syndrome. ( 28882496 )
2017
17
Characteristics of cellular composition in malignant pericardial effusion and its association with the clinical course of carcinomatous pericarditis. ( 29300912 )
2017
18
Huge pericardial effusion with subcutaneous emphysema, pneumomediastinum and pneumopericardium in anorexia nervosa. ( 28799456 )
2017
19
Chest Pain Due to Pericardial Effusion as Initial Presenting Feature of Rheumatoid Arthritis: Case Report and Review of the Literature. ( 28868101 )
2017
20
Pericardial effusion is correlated with clinical outcome after pulmonary artery denervation for pulmonary arterial hypertension. ( 28903327 )
2017
21
Intra-Pericardial Use of Recombinant Factor VIIa in a Patient With Acute Hemorrhagic Pericardial Effusion Following Transcutaneous Aortic Valve Replacement-A Case Report. ( 28934519 )
2017
22
Chondrosarcoma: Extrinsic Compression of the Right Ventricle and Pericardial Effusion. ( 28709860 )
2017
23
Uremic pericarditis, pericardial effusion, and constrictive pericarditis in end-stage renal disease: Insights and pathophysiology. ( 28873222 )
2017
24
Use of Yunnan Baiyao and epsilon aminocaproic acid in dogs with right atrial masses and pericardial effusion. ( 27669112 )
2017
25
Novel echocardiographic prognostic markers for cardiac tamponade in patients with large malignant pericardial effusions: A paradigm shift from flow to tissue imaging. ( 28685870 )
2017
26
Incidence and Predictors of Pericardial Effusion After Chemoradiation Therapy for Locally Advanced Non-Small Cell Lung Cancer. ( 28816165 )
2017
27
Case report: A case of pericardial effusion presenting to primary care. ( 28889141 )
2017
28
Pericardial Effusion as a Presenting Symptom of Hashimoto Thyroiditis: A Case Report. ( 29240719 )
2017
29
Massive Pericardial Effusion and Tamponade Can Be a First Sign of Familial Mediterranean Fever. ( 28763406 )
2017
30
Prevalence of vomiting in dogs with pericardial effusion. ( 28079972 )
2017
31
Upper gastrointestinal tract symptoms are predictors of postoperative large pericardial effusion in cardiac surgery. ( 28839323 )
2017
32
Ethanol injection into the Marshall vein provoking a pericardial effusion resulting in a fatal complication in a patient with persistent atrial fibrillation. ( 28878915 )
2017
33
Comparison of distinctive clinical and cardiac magnetic resonance features between ST elevation myocardial infarction patients with incomplete myocardial rupture and those with moderate to severe pericardial effusion. ( 28730842 )
2017
34
A rare cause of pericardial effusion and ascites: POEMS syndrome. ( 29333225 )
2017
35
Tacrolimus as a Rare Cause of Pericardial Effusion in a Renal Transplant Recipient. ( 29326779 )
2017
36
Parainfluenza 3 Respiratory Infection Associated with Pericardial Effusion in a Very Low Birthweight Infant. ( 29204302 )
2017
37
Incidence and Outcome of Pericardial Effusion in Pediatric Patients After Hematopoietic Stem Cell Transplant: A Single-institution Experience. ( 28945662 )
2017
38
Intracerebral Bleeding and Massive Pericardial Effusion as Presenting Symptoms of Myxedema Crisis. ( 28255471 )
2017
39
Factors Affecting Survival in Children With Pericardial Effusion After Hematopoietic Stem Cell Transplantation. ( 29338379 )
2017
40
Infantile Systemic Hyalinosis Complicated with Right Atrial Thrombus and Pericardial Effusion in an Infant. ( 25458638 )
2017
41
A small pericardial effusion is a marker of complicated hospitalization in patients with community-acquired pneumonia. ( 29247912 )
2017
42
Large Pericardial Mass Mimicking Pericardial Effusion. ( 29184620 )
2017
43
Relapsed Multiple Myeloma Presenting as Intracranial Plasmacytoma and Malignant Pericardial Effusion following Recent Allogeneic Stem Cell Transplantation. ( 28868016 )
2017
44
Drug-Induced by Systemic Lupus Erythematosus Presenting as Recurrent Pericardial Effusion After Mitral Valve Repair. ( 29202555 )
2017
45
Acute rhabdomyolysis and delayed pericardial effusion in an Italian patient with Ebola virus disease: a case report. ( 28854896 )
2017
46
Yellow Nail Syndrome Presenting With a Pericardial Effusion: A Case Report and Review of the Literature. ( 29067826 )
2017
47
Case of generalized pustular psoriasis presenting with both pleural effusion and pericardial effusion collection. ( 28636215 )
2017
48
Diagnosis of systemic inflammatory diseases among patients admitted for acute pericarditis with pericardial effusion. ( 28937580 )
2017
49
ANA-Negative Hydralazine-Induced Pericardial Effusion. ( 29391867 )
2017
50
Malignant pericardial effusion (MPE) - Sufficient treatment by radiotherapy. ( 27814982 )
2016

Variations for Pericardial Effusion

Expression for Pericardial Effusion

Search GEO for disease gene expression data for Pericardial Effusion.

Pathways for Pericardial Effusion

Pathways related to Pericardial Effusion according to GeneCards Suite gene sharing:

(show all 15)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.24 FGF2 HIF1A IL6 TNFRSF1A VEGFA
2
Show member pathways
11.87 FGF2 NPPA NPPB TNFRSF1A
3 11.85 FGF2 IL6 VEGFA
4 11.64 FGF2 HIF1A REN
5
Show member pathways
11.52 ADA HIF1A VEGFA
6 11.51 FGF2 HIF1A IL6 VEGFA
7
Show member pathways
11.45 IL6 TNFRSF1A VEGFA
8 11.34 HIF1A IL6 VEGFA
9 11.29 FGF2 IL6 VEGFA
10 11.24 FGF2 PIK3C2A VEGFA
11 10.92 HIF1A IL6 NPPA VEGFA
12
Show member pathways
10.91 CRP HIF1A VEGFA
13 10.82 CRP IL6
14 10.51 FGF2 HIF1A VEGFA
15 10.46 HIF1A VEGFA

GO Terms for Pericardial Effusion

Cellular components related to Pericardial Effusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.61 CRP FGF2 IL6 NPPA NPPB PVR
2 cell surface GO:0009986 9.55 ACVRL1 ADA PVR TNFRSF1A VEGFA
3 extracellular space GO:0005615 9.32 ADA CRP FGF2 IL6 NPPA NPPB

Biological processes related to Pericardial Effusion according to GeneCards Suite gene sharing:

(show all 23)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.91 CRP HIF1A IL6 VEGFA
2 regulation of receptor activity GO:0010469 9.8 FGF2 IL6 NPPA NPPB VEGFA
3 angiogenesis GO:0001525 9.78 ACVRL1 FGF2 HIF1A VEGFA
4 negative regulation of cell growth GO:0030308 9.74 ACVRL1 NPPA NPPB
5 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.63 IL6 TNFRSF1A VEGFA
6 positive regulation of heart rate GO:0010460 9.61 ADA NPPA
7 camera-type eye morphogenesis GO:0048593 9.6 HIF1A VEGFA
8 positive regulation of neuroblast proliferation GO:0002052 9.59 HIF1A VEGFA
9 positive regulation of chemokine production GO:0032722 9.58 HIF1A IL6
10 regulation of blood vessel size GO:0050880 9.58 NPPA NPPB
11 positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 9.56 HIF1A VEGFA
12 positive regulation of angiogenesis GO:0045766 9.56 ACVRL1 FGF2 HIF1A VEGFA
13 cell migration involved in sprouting angiogenesis GO:0002042 9.55 FGF2 VEGFA
14 receptor guanylyl cyclase signaling pathway GO:0007168 9.52 NPPA NPPB
15 retina vasculature development in camera-type eye GO:0061298 9.51 ACVRL1 HIF1A
16 positive regulation of blood vessel endothelial cell migration GO:0043536 9.5 FGF2 HIF1A VEGFA
17 negative regulation of lipid storage GO:0010888 9.49 CRP IL6
18 positive regulation of endothelial cell proliferation GO:0001938 9.46 ACVRL1 FGF2 HIF1A VEGFA
19 negative regulation of thymocyte apoptotic process GO:0070244 9.43 ADA HIF1A
20 positive regulation of transcription from RNA polymerase II promoter in response to hypoxia GO:0061419 9.37 HIF1A VEGFA
21 regulation of blood pressure GO:0008217 9.26 ACVRL1 NPPA NPPB REN
22 response to hypoxia GO:0001666 9.02 ACVRL1 ADA HIF1A NPPA VEGFA
23 positive regulation of transcription by RNA polymerase II GO:0045944 10.01 ACVRL1 FGF2 HIF1A IL6 TNFRSF1A VEGFA

Molecular functions related to Pericardial Effusion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone receptor binding GO:0051427 8.62 NPPA NPPB

Sources for Pericardial Effusion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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