MCID: PRC010
MIFTS: 35

Pericardial Mesothelioma

Categories: Cancer diseases, Cardiovascular diseases

Aliases & Classifications for Pericardial Mesothelioma

MalaCards integrated aliases for Pericardial Mesothelioma:

Name: Pericardial Mesothelioma 12 14 69
Malignant Mesothelioma of Pericardium 12
Malignant Pericardial Mesothelioma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6201
ICD10 32 C45.2
SNOMED-CT 64 109383000 187885008

Summaries for Pericardial Mesothelioma

MalaCards based summary : Pericardial Mesothelioma, also known as malignant mesothelioma of pericardium, is related to regional odontodysplasia and malignant peritoneal mesothelioma. An important gene associated with Pericardial Mesothelioma is MUC1 (Mucin 1, Cell Surface Associated), and among its related pathways/superpathways are Cytoskeletal Signaling and Cytoskeleton remodeling Neurofilaments. Affiliated tissues include heart, liver and brain, and related phenotypes are Negative genetic interaction between PTEN-/- and PTEN+/+ and cellular

Related Diseases for Pericardial Mesothelioma

Diseases related to Pericardial Mesothelioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 194)
# Related Disease Score Top Affiliating Genes
1 regional odontodysplasia 10.6 KRT19 VIM
2 malignant peritoneal mesothelioma 10.6 MUC1 VIM
3 reticulum cell sarcoma 10.5 MUC1 S100A1 VIM
4 filamentary keratitis 10.5 KRT10 MUC1 MUC16
5 splenic tuberculosis 10.5 KRT19 SMUG1
6 basal cell carcinoma, infundibulocystic 10.5 KRT10 PTGER4
7 intrahepatic bile duct adenoma 10.5 KRT19 KRT7
8 polymorphous low-grade adenocarcinoma 10.5 MUC1 S100A1 VIM
9 anal gland adenocarcinoma 10.5 KRT19 KRT7
10 sternum cancer 10.5 SMUG1 VIM
11 proliferating trichilemmal cyst 10.5 KRT19 KRT7
12 biphasic synovial sarcoma 10.5 MUC1 VIM
13 anus adenocarcinoma 10.5 KRT19 KRT7
14 corpus luteum cyst 10.5 MUC16 SMUG1
15 fibrous meningioma 10.5 MUC1 VIM
16 sarcomatoid mesothelioma 10.5 MUC1 THBD VIM
17 chordoid meningioma 10.5 MUC1 VIM
18 pilomatrix carcinoma 10.5 ENO2 MUC1
19 anus basaloid carcinoma 10.5 KRT7 PTGER4
20 intracranial cysts 10.5 ENO2 MUC1
21 vulvar intraepithelial neoplasia 10.5 KRT10 KRT7
22 cutaneous adenocystic carcinoma 10.5 KRT19 KRT7
23 clear cell meningioma 10.4 MUC1 VIM
24 glandular cystitis 10.4 KRT7 MUC1
25 sinonasal undifferentiated carcinoma 10.4 ENO2 MUC1
26 spindle cell rhabdomyosarcoma 10.4 MB MUC1
27 mast-cell sarcoma 10.4 MPO VIM
28 bile duct mucoepidermoid carcinoma 10.4 KRT7 MUC1
29 parachordoma 10.4 KRT7 MUC1 VIM
30 syringocystadenoma papilliferum 10.4 MUC1 VIM
31 malignant mixed mullerian tumor 10.4 KRT7 MUC1 VIM
32 eccrine porocarcinoma 10.4 KRT7 MUC1 VIM
33 monophasic synovial sarcoma 10.4 KRT7 MUC1 VIM
34 bednar tumor 10.4 ENO2 VIM
35 primitive neuroectodermal tumor of the cervix uteri 10.4 ENO2 VIM
36 hidradenoma 10.4 KRT7 MUC1 VIM
37 malignant peripheral nerve sheath tumor 10.4 MUC1 S100A1 VIM
38 mucinous cystadenocarcinoma 10.4 KRT7 MUC1 VIM
39 spindle cell sarcoma 10.4 KRT7 MUC1 VIM
40 spiradenoma 10.4 KRT7 MUC1 VIM
41 dermoid cyst 10.4 KRT7 MUC1 VIM
42 biliary papillomatosis 10.4 KRT19 KRT7 MUC1
43 malignant syringoma 10.4 KRT7 PTGER4
44 lipoadenoma 10.4 KRT19 KRT7 MUC1
45 malignant ectomesenchymoma 10.4 ENO2 S100A1
46 papillary adenocarcinoma 10.4 KRT7 MUC1 VIM
47 secretory meningioma 10.4 KRT7 MUC1 VIM
48 chordoma 10.4 KRT7 MUC1 VIM
49 endosalpingiosis 10.4 KRT7 MUC1 PTGER4
50 oncocytoma 10.4 KRT7 MUC1 VIM

Graphical network of the top 20 diseases related to Pericardial Mesothelioma:



Diseases related to Pericardial Mesothelioma

Symptoms & Phenotypes for Pericardial Mesothelioma

GenomeRNAi Phenotypes related to Pericardial Mesothelioma according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Negative genetic interaction between PTEN-/- and PTEN+/+ GR00255-A-3 9.1 CD99 ENO2 KRT10 MPO SMUG1 THBD

MGI Mouse Phenotypes related to Pericardial Mesothelioma:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.36 ENO2 ERF FOXK1 KRT19 KRT7 MB

Drugs & Therapeutics for Pericardial Mesothelioma

Search Clinical Trials , NIH Clinical Center for Pericardial Mesothelioma

Genetic Tests for Pericardial Mesothelioma

Anatomical Context for Pericardial Mesothelioma

MalaCards organs/tissues related to Pericardial Mesothelioma:

38
Heart, Liver, Brain

Publications for Pericardial Mesothelioma

Articles related to Pericardial Mesothelioma:

(show top 50) (show all 113)
# Title Authors Year
1
A second case of pericardial mesothelioma mimicking systemic lupus erythematosus in the literature in over 30 years: a case report. ( 28351431 )
2017
2
Primary pericardial mesothelioma in a 48-year-old patient. ( 29171839 )
2017
3
Malignant pericardial mesothelioma : AA systematic review of current practice. ( 28130567 )
2017
4
Primary pericardial mesothelioma and asbestos exposure: a rare fatal disease. ( 28500034 )
2017
5
Pericardial mesothelioma presenting as a suspected ST-elevation myocardial infarction. ( 28343785 )
2017
6
F-18 FDG PET/CT images of a rare primer cardiac tumour: Primary Pericardial Mesothelioma. ( 27515105 )
2016
7
Sarcomatoid Type Primary Pericardial Mesothelioma with a Long-term Survival after the Onset of Cardiac Tamponade. ( 27803412 )
2016
8
Pericardial Effusion due to Primary Malignant Pericardial Mesothelioma: A Common Finding but an Uncommon Cause. ( 28003826 )
2016
9
Pericardial mesothelioma. ( 27318362 )
2016
10
Primary malignant pericardial mesothelioma with increased serum mesothelin diagnosed by surgical pericardial resection: A case report. ( 27900083 )
2016
11
Positive response of a primary malignant pericardial mesothelioma to pemetrexed plus cisplatin followed by pemetrexed maintenance chemotherapy: A case report. ( 27347127 )
2016
12
Successful palliation for an aged patient with primary pericardial mesothelioma. ( 26376726 )
2015
13
Pericardial Mesothelioma in a Yellow-naped Amazon Parrot ( Amazona auropalliata ). ( 25867668 )
2015
14
Endobronchial ultrasound-guided transbronchial needle aspiration in a patient with pericardial mesothelioma. ( 25742892 )
2015
15
A rare cause of heart failure with preserved ejection fraction: primary pericardial mesothelioma masquerading as pericardial constriction. ( 24654246 )
2014
16
Primary malignant pericardial mesothelioma-a rare cause of superior vena cava thrombosis and constrictive pericarditis. ( 25590007 )
2014
17
A rare case of primary malignant pericardial mesothelioma. ( 25250196 )
2014
18
Primary pericardial mesothelioma: a rare entity. ( 23840993 )
2013
19
Primary pericardial mesothelioma: A rare cause of constrictive pericarditis. ( 24887935 )
2013
20
Cardiac MRI findings in a dog with a diffuse pericardial mesothelioma and pericardial effusion. ( 24051256 )
2013
21
Primary pericardial mesothelioma in a 19-year-old presenting as pericarditis. ( 23353042 )
2013
22
Mixed form of pericardial mesothelioma with osseous differentiation in a dog. ( 23578582 )
2013
23
Three-year survival after surgery for primary malignant pericardial mesothelioma: report of a case. ( 23408086 )
2013
24
Primary sarcomatoid malignant pericardial mesothelioma. ( 23291695 )
2013
25
Unexpected malignant pericardial mesothelioma presenting as pericardial constriction. ( 23094904 )
2012
26
A case of primary pericardial mesothelioma detected by 18F-FDG PET/CT. ( 22475912 )
2012
27
A case report of an extremely rare and aggressive tumor: primary malignant pericardial mesothelioma. ( 22826778 )
2012
28
Fluorine-18 fluoro-2-deoxyglucose positron emission tomography/computed tomography in a case of suspected primary pericardial mesothelioma. ( 23919083 )
2012
29
Primary pericardial mesothelioma unique case and literature review. ( 22740748 )
2012
30
Primary malignant pericardial mesothelioma presenting as acute pericarditis. ( 22509441 )
2012
31
False aneurysm of ascending aorta due to pericardial mesothelioma. ( 22593561 )
2012
32
A case of malignant pericardial mesothelioma with constrictive pericarditis physiology misdiagnosed as pericardial metastatic cancer. ( 21779289 )
2011
33
Pericardial mesothelioma and asbestos exposure. ( 21156353 )
2011
34
Primary malignant pericardial mesothelioma presenting as effusive-constrictive pericarditis. ( 21828406 )
2011
35
Malignant pericardial mesothelioma. ( 20643560 )
2011
36
Primary pericardial mesothelioma in an asbestos-exposed patient with previous heart surgery. ( 20530447 )
2010
37
Surprising finding of a primary pericardial mesothelioma. ( 20339921 )
2010
38
Primary malignant pericardial mesothelioma mimicking pericardial metastasis from adenocarcinoma. ( 21102264 )
2010
39
Malignant pericardial mesothelioma following thoracal radiotherapy; dissemination from pericardium to pleura. ( 21038142 )
2010
40
Malignant pericardial mesothelioma with response to chemotherapy. ( 19861909 )
2009
41
Primary malignant pericardial mesothelioma - a rare cause of pericardial effusion and consecutive constrictive pericarditis: a case report. ( 19918293 )
2009
42
Primary Pericardial Mesothelioma: Report of a Patient and Literature Review. ( 20740175 )
2009
43
Fatal hemopericardial tamponade due to primary pericardial mesothelioma: a case report. ( 20003222 )
2009
44
Primary malignant pericardial mesothelioma presenting as pericardial constriction. ( 19131929 )
2008
45
Primary pericardial mesothelioma. ( 17936406 )
2008
46
Pericardial mesothelioma in a Bengal tiger (Panthera tigris). ( 18432108 )
2008
47
F-18 fluorodeoxyglucose PET/CT scanning in the diagnostic work-up of a primary pericardial mesothelioma: a case report. ( 18347518 )
2008
48
Intracavitary mass as the initial manifestation of primary pericardial mesothelioma: a case report. ( 17495278 )
2007
49
Primary pericardial mesothelioma: a rare cardiac malignancy. ( 17640193 )
2007
50
Report of a case of pericardial mesothelioma with liver metastases responding well to pemetrexed and platinum-based chemotherapy. ( 17762349 )
2007

Variations for Pericardial Mesothelioma

Expression for Pericardial Mesothelioma

Search GEO for disease gene expression data for Pericardial Mesothelioma.

Pathways for Pericardial Mesothelioma

Pathways related to Pericardial Mesothelioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.51 KRT10 KRT19 KRT7 MUC1 VIM
2
Show member pathways
11.37 KRT19 KRT7 VIM
3 9.86 HBA1 MB

GO Terms for Pericardial Mesothelioma

Cellular components related to Pericardial Mesothelioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.76 ENO2 HBA1 KRT10 MPO MSLN MUC1
2 extracellular exosome GO:0070062 9.36 ENO2 GFPT1 HBA1 KRT10 KRT19 KRT7
3 intermediate filament GO:0005882 9.26 KRT10 KRT19 KRT7 VIM

Biological processes related to Pericardial Mesothelioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxygen transport GO:0015671 8.62 HBA1 MB

Molecular functions related to Pericardial Mesothelioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxygen carrier activity GO:0005344 8.62 HBA1 MB

Sources for Pericardial Mesothelioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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