Aliases & Classifications for Pericarditis

MalaCards integrated aliases for Pericarditis:

Name: Pericarditis 12 28 51 41 14 69 59

Classifications:



External Ids:

Disease Ontology 12 DOID:1787
MeSH 41 D010493
NCIt 46 C34915
SNOMED-CT 64 3238004
ICD10 32 I32 I32.8
UMLS 69 C0031046

Summaries for Pericarditis

PubMed Health : 59
About pericarditis: Pericarditis (PER-ih-kar-DI-tis) is a condition in which the membrane, or sac, around your heart is inflamed. This sac is called the pericardium (per-ih-KAR-de-um).The pericardium holds the heart in place and helps it work properly. The sac is made of two thin layers of tissue that enclose your heart. Between the two layers is a small amount of fluid. This fluid keeps the layers from rubbing against each other and causing friction.

MalaCards based summary : Pericarditis is related to idiopathic recurrent pericarditis and constrictive pericarditis, and has symptoms including chest pain An important gene associated with Pericarditis is PRG4 (Proteoglycan 4), and among its related pathways/superpathways are Akt Signaling and Toll-Like receptor Signaling Pathways. The drugs Coal tar and Colchicine have been mentioned in the context of this disorder. Affiliated tissues include heart, kidney and liver, and related phenotypes are cardiovascular system and hematopoietic system

Disease Ontology : 12 A pericardium disease that is characterized by an inflammation of the pericardium and has symptom chest pain.

Wikipedia : 72 Pericarditis is inflammation of the pericardium (the fibrous sac surrounding the heart). Symptoms... more...

Related Diseases for Pericarditis

Diseases related to Pericarditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 484)
# Related Disease Score Top Affiliating Genes
1 idiopathic recurrent pericarditis 34.0 MEFV TNFRSF1A
2 constrictive pericarditis 33.9 ADA NPPB PRG4
3 systemic onset juvenile idiopathic arthritis 31.4 IL1B MEFV TNF
4 arthropathy 30.4 CRP PRG4 TNF
5 endocarditis 30.3 CRP IL6 TNF
6 myocarditis 30.0 IL6 NPPB TNF
7 pericardial effusion 30.0 ADA CRP IL6 NPPB TNFRSF1A
8 pleural empyema 30.0 ADA CRP
9 periodic fever, familial, autosomal dominant 30.0 MEFV TNF TNFRSF1A
10 vasculitis 29.8 CRP MEFV TNF
11 hyper-igd syndrome 29.8 CRP TNFRSF1A
12 infective endocarditis 29.8 CRP IL6 TNF
13 pneumonia 29.7 CRP IL1B IL6 TNF
14 streptococcal toxic-shock syndrome 29.7 IL6 TNF
15 brucellosis 29.7 CRP IL6 MEFV TNF
16 takayasu arteritis 29.6 CRP IL6 TNF
17 angina pectoris 29.6 CRP IL6
18 coronary artery anomaly 29.5 CRP IL6 NPPB
19 acute myocardial infarction 29.5 CRP NPPB TNNT2
20 haemophilus influenzae 29.4 IL1B TNF
21 pulmonary disease, chronic obstructive 29.4 CRP IL6 TNF
22 cardiogenic shock 29.4 CRP IL6 NPPB
23 rheumatoid arthritis 29.3 CRP IL1B IL6 TNF TNFRSF1A
24 listeria meningitis 29.3 ADA TNF
25 pleurisy 29.2 ADA CRP MEFV TNF
26 crohn's disease 29.1 CRP IL1B IL6 TNF
27 laryngitis 29.1 IL1B IL6 TNF
28 toxic shock syndrome 29.0 IL1B IL6 TNF
29 graft-versus-host disease 29.0 IL1B IL6 TNF
30 colitis 29.0 IL1B IL6 TNF
31 hypertrophic cardiomyopathy 29.0 IL6 NPPB TNF TNNT2
32 systemic lupus erythematosus 29.0 CRP IL1B IL6 TNF TNFRSF1A
33 familial mediterranean fever 29.0 CRP IL1B MEFV TNF TNFRSF1A
34 diabetes mellitus 28.9 CRP IL1B IL6 TNF
35 psoriatic arthritis 28.8 CRP IL1B TNF TNFRSF1A
36 adult-onset still's disease 28.8 CRP IL1B IL6 MEFV TNF
37 leptospirosis 28.8 CRP IL1B IL6 TNF
38 lyme disease 28.8 CRP IL1B IL6 TNF
39 juvenile rheumatoid arthritis 28.8 CRP IL1B IL6 TNF
40 ulcerative colitis 28.8 CRP IL1B IL6 TNF
41 meningitis 28.7 ADA CRP IL1B IL6 IRAK4 TNF
42 myocardial infarction 28.7 CRP IL1B IL6 NPPB TNF TNNT2
43 heart disease 28.7 CRP IL6 NPPB TNF TNNT2
44 multiple sclerosis 28.6 IL1B IL6 TNF TNFRSF1A
45 peritonitis 28.4 ADA CRP IL1B IL6 MEFV TNF
46 psoriasis 28.3 IL1B IL6 TNF TNFRSF1A TRAF3IP2
47 arteries, anomalies of 28.1 CRP IL1B IL6 NPPB TNF TNNT2
48 dilated cardiomyopathy 27.7 CRP IL1B IL6 NPPB TNF TNNT2
49 camptodactyly-arthropathy-coxa vara-pericarditis syndrome 12.5
50 histoplasmosis pericarditis 12.1

Graphical network of the top 20 diseases related to Pericarditis:



Diseases related to Pericarditis

Symptoms & Phenotypes for Pericarditis

Symptoms:

12
  • chest pain

MGI Mouse Phenotypes related to Pericarditis:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.86 TNF TNFRSF1A ADA TNNT2 CRP TRAF3IP2
2 hematopoietic system MP:0005397 9.81 TNF TNFRSF1A ADA TRAF3IP2 HRH4 IL1B
3 homeostasis/metabolism MP:0005376 9.7 TNFRSF1A ADA TNNT2 CRP TRAF3IP2 HRH4
4 immune system MP:0005387 9.32 TNFRSF1A ADA CRP TRAF3IP2 HRH4 IL1B

Drugs & Therapeutics for Pericarditis

PubMedHealth treatment related to Pericarditis: 59

Most cases of pericarditis are mild; they clear up on their own or with rest and simple treatment. Other times, more intense treatment is needed to prevent complications. Treatment may include medicines and, less often, procedures or surgery.The goals of treatment include:Reducing pain and inflammationTreating the underlying cause, if it's knownChecking for complications

Drugs for Pericarditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 45)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Coal tar Approved Phase 4,Phase 3 8007-45-2
2
Colchicine Approved Phase 4,Phase 3,Phase 2,Early Phase 1 64-86-8 2833 6167
3
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
4 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Early Phase 1
5 Interleukin 1 Receptor Antagonist Protein Phase 4,Early Phase 1
6 Antimitotic Agents Phase 4,Phase 3,Phase 2,Early Phase 1
7 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2
8 Peripheral Nervous System Agents Phase 4,Phase 3
9 Fibrinolytic Agents Phase 4,Phase 3
10 Analgesics Phase 4
11 Analgesics, Non-Narcotic Phase 4
12 Anti-Inflammatory Agents, Non-Steroidal Phase 4
13 Antipyretics Phase 4
14 Cyclooxygenase Inhibitors Phase 4
15 Platelet Aggregation Inhibitors Phase 4
16
Methylprednisolone Approved, Vet_approved Phase 3 83-43-2 6741
17
Prednisolone Approved, Vet_approved Phase 3 50-24-8 5755
18 Antiemetics Phase 3
19 Antineoplastic Agents, Hormonal Phase 3,Phase 2
20 Autonomic Agents Phase 3
21 Gastrointestinal Agents Phase 3
22 glucocorticoids Phase 3,Phase 2
23 Hormone Antagonists Phase 3,Phase 2
24 Hormones Phase 3,Phase 2
25 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2
26 Methylprednisolone acetate Phase 3
27 Methylprednisolone Hemisuccinate Phase 3
28 Neuroprotective Agents Phase 3
29 Prednisolone acetate Phase 3
30 Prednisolone hemisuccinate Phase 3
31 Prednisolone phosphate Phase 3
32 Protective Agents Phase 3
33 Vaccines Phase 3
34 Plasminogen Phase 3
35 Tissue Plasminogen Activator Phase 3
36
Abatacept Approved Phase 2 332348-12-6 10237
37
Prednisone Approved, Vet_approved Phase 2 53-03-2 5865
38
Eplerenone Approved Phase 2 107724-20-9 443872 150310
39 Immunosuppressive Agents Phase 2
40 Adrenergic beta-Antagonists Phase 2
41 Atorvastatin Calcium Phase 2 134523-03-8
42 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 2
43
Iron Approved 7439-89-6 23925
44
Cyclophosphamide Approved, Investigational 50-18-0, 6055-19-2 2907
45
Menthol Approved 2216-51-5 16666

Interventional clinical trials:

(show all 37)

# Name Status NCT ID Phase Drugs
1 AnakInRa for Treatment of Recurrent Idiopathic Pericarditis (AIRTRIP) Completed NCT02219828 Phase 4 Anakinra;Placebo
2 Study of Colchicine to Treat and Prevent Recurrent Pericarditis After Failure of Conventional Treatment. Completed NCT00235079 Phase 4 Colchicine;Placebo
3 Anti-inflammatory Effects of Colchicine in PCI Recruiting NCT01709981 Phase 4 Colchicine;Placebo
4 Benign Acute Pericarditis: Brief Versus Longer Treatment Using Aspirin Terminated NCT00946907 Phase 4 Aspirin;placebo
5 Study of Colchicine to Treat Acute Pericarditis and Prevent Recurrences Completed NCT00128453 Phase 3 Colchicine (for 3 months);Placebo
6 Study of Colchicine to Treat and Prevent Recurrent Pericarditis (First Episode) Completed NCT00128414 Phase 3 Colchicine (for 6 months);Placebo
7 A Trial of Adjunctive Prednisolone and Mycobacterium w Immunotherapy in Tuberculous Pericarditis Completed NCT00810849 Phase 3 Prednisolone
8 Study of Colchicine to Prevent the Postpericardiotomy Syndrome Completed NCT00128427 Phase 3 Colchicine (for 1 month)
9 IMPI 2 - A Trial of Intrapericardial Alteplase in Large Pericardial Effusion Recruiting NCT02673879 Phase 3
10 Myocardial Screening in Fetuses With Congenital Cytomegalovirus (CMV) Infection Not yet recruiting NCT02787382 Phase 3
11 Abatacept in the Treatment and Prevention of Active Systemic Lupus Erythematosus (SLE) Flares in Combination With Prednisone Completed NCT00119678 Phase 2 Abatacept;Placebo;Prednisone;Abatacept
12 Interest of COLchicine in the Treatment of Patients With Acute Myocardial INfarction and With Inflammatory Response Completed NCT02363725 Phase 2 Colchimax®;Conventional treatment
13 A Randomized Comparison of Radiation Therapy Techniques in the Management of Node Positive Breast Cancer Completed NCT00581256 Phase 1, Phase 2
14 Septal Shift for the Diagnosis of COnstrictive Pericarditis: The Impact of Inspiratory Effort Quantification on Deep Breathing Manoeuvres Unknown status NCT02685371
15 Noise, a Risk for Heart in Airplane Pilots Unknown status NCT01063582
16 Safety of Early Discharge Following Low Risk Myocardial Infarction Unknown status NCT01868256
17 Transient ECG Changes in Patients With Acute Biliary Disease Unknown status NCT01706068
18 ST Elevation in Acute Chest Pain; Could Measurement of Lipoprotein-associated Phospholipase A2 (Lp-PLA2) be Helpful to the Clinician? Completed NCT01041339
19 Apolipoprotein CIII Reduction Via Colchicine Completed NCT02083510 Early Phase 1 Colchicine
20 Epipericardial Fat Necrosis: A Misdiagnosed Condition Completed NCT01903980
21 Safety Surveillance Study of ACAM2000® Vaccinia Vaccine Completed NCT00927719
22 Evaluation of Myocardial Iron Deposition in Patients of Heart Failure Using T2* MR Imaging Completed NCT02527330
23 Detection of Enterovirus RNA in Atheromatous Lesions Completed NCT00674531
24 Cardiovascular Diseases in HIV-infected Patients HIV-HEART Study: 7.5 Years Follow-up Completed NCT01667068
25 Cardiovascular Diseases in HIV-infected Patients HIV-HEART Study: 5 Years Follow-up Completed NCT01196273
26 Cardiomyopathy Following Stem Cell Transplantation Completed NCT00352209
27 Prognostic Biomarkers in Patients With Acute Pericarditis Recruiting NCT02754713
28 Improvement of the Etiological Diagnosis of the Pericarditis Recruiting NCT02828085
29 Immunological Profile in Relation to Cardiac Geometry in Hypertension Recruiting NCT02165241
30 Feasibility Study of a Left Atrial Appendage Closure Device in Patients With Atrial Fibrillation Recruiting NCT02583178
31 ACAM2000® Myopericarditis Registry Active, not recruiting NCT01395082
32 A Survey of Hospitalizations in Cardiology Units in Sub-Saharan Africa Active, not recruiting NCT03231449
33 Treatment of Acute Pericarditis With Anakinra Not yet recruiting NCT03224585 Early Phase 1 Anakinra;Placebo
34 Management of Pericarditis in Children. Not yet recruiting NCT03253315
35 The Artificial Kidney Initiation in Kidney Injury 2 Not yet recruiting NCT03396757
36 Constrictive Pericarditis in the Adult Congenital Cardiac Population Terminated NCT00268086
37 New Methods to Diagnose Constrictive Pericarditis Withdrawn NCT02027350

Search NIH Clinical Center for Pericarditis

Cochrane evidence based reviews: pericarditis

Genetic Tests for Pericarditis

Genetic tests related to Pericarditis:

# Genetic test Affiliating Genes
1 Pericarditis 28

Anatomical Context for Pericarditis

MalaCards organs/tissues related to Pericarditis:

38
Heart, Kidney, Liver, Breast, Lung, Bone, Bone Marrow

Publications for Pericarditis

Articles related to Pericarditis:

(show top 50) (show all 1310)
# Title Authors Year
1
Constrictive Pericarditis as a Long-term Undetermined Etiology of Ascites and Edema. ( 29321423 )
2018
2
Implantable epicardial cardioverter-defibrillator-induced localized constrictive pericarditis. ( 29049636 )
2018
3
Case report of an unusual combination of purulent pericarditis and false aneurysm of the ascending aorta. ( 29378612 )
2018
4
ECG Spot Diagnosis: Acute Pericarditis. ( 29432566 )
2018
5
Recurrent purulent pericarditis secondary to a giant bronchogenic cyst. ( 29029080 )
2018
6
A rare case of pericarditis and pleural empyema secondary to transdiaphragmatic extension of pyogenic liver abscess. ( 29334903 )
2018
7
Clinical features, management and outcome of patients with constrictive pericarditis - Experience from a third world country. ( 29296059 )
2018
8
An oil refinery worker at Kaohsiung, with Pseudoxanthomonas kaohsiungensis bloodstream infection presenting as chronic pericarditis and masquerading as tuberculosis pericarditis. ( 29366692 )
2018
9
Primary purulent bacterial pericarditis due to Streptococcus intermedius in an immunocompetent adult: a case report. ( 29397796 )
2018
10
Acute pericarditis following endoscopy. ( 29437737 )
2018
11
Genotype-phenotype investigation of 35 patients from 11 unrelated families with camptodactyly-arthropathy-coxa vara-pericarditis (CACP) syndrome. ( 29397575 )
2018
12
Purulent pericarditis, an unusual complication of pneumococcal pneumonia: a case report. ( 29322942 )
2018
13
Acute pericarditis following second-generation cryoballoon ablation for atrial fibrillation. ( 29445985 )
2018
14
Pericardiectomy for Constrictive Pericarditis: An Institution's 21 Years Experience. ( 28780766 )
2017
15
A case report of combined radical pericardiectomy and beating heart coronary artery bypass grafting in a patient with tubercular chronic constrictive pericarditis with coronary artery disease. ( 28994689 )
2017
16
Correction to: A Case of Rheumatic Fibrinous Pericarditis. ( 28069668 )
2017
17
Constrictive pericarditis from an endocardial pacemaker lead. ( 28710300 )
2017
18
Pericardial interstitial cell senescence responsible for pericardial structural remodeling in idiopathic and postsurgical constrictive pericarditis. ( 28456362 )
2017
19
Incidence and Significance of Adhesions Encountered during Epicardial Mapping and Ablation of Ventricular Tachycardia in Patients with no History of Prior Cardiac Surgery or Pericarditis. ( 28917555 )
2017
20
Constrictive pericarditis-induced shunting through a PFO: Persistence despite pericardiectomy. ( 28649486 )
2017
21
A mysterious cause of constrictive pericarditis: unfolding of the missing link. ( 29293944 )
2017
22
Constrictive pericarditis caused by Cutibacterium (Propionibacterium) acnes: A case report and review of literature. ( 29021959 )
2017
23
Constrictive Pericarditis ( 29083701 )
2017
24
Effectiveness and long-term outcomes of surgical intervention for constrictive epicardium in constrictive pericarditis. ( 29080093 )
2017
25
Constrictive Pericarditis 5 Months after Radiation Therapy in a 62-Year-Old Woman with Esophageal Cancer. ( 29276442 )
2017
26
Purulent constrictive pericarditis caused by Salmonella enteritidis in a patient with adult-onset Still's disease: A case report. ( 29390286 )
2017
27
Importance of Clinical and Laboratory Findings in the Diagnosis and Surgical Prognosis of Patients with Constrictive Pericarditis. ( 28977057 )
2017
28
Characteristics of cellular composition in malignant pericardial effusion and its association with the clinical course of carcinomatous pericarditis. ( 29300912 )
2017
29
Transitory effusive-constrictive pericarditis. ( 29169889 )
2017
30
Hospitalized Elderly Patients for Acute Pericarditis Deserve More Clinical Attention and a Closer Follow-up Monitoring. ( 29309548 )
2017
31
Streptococcus intermedius: An Unusual Case of Purulent Pericarditis. ( 28932608 )
2017
32
Acute pneumonitis and pericarditis related to alemtuzumab therapy in relapsing-remitting multiple sclerosis. ( 27888417 )
2017
33
Idiopathic relapsing acute pericarditis: Report of one case with favorable response to anakinra. ( 28919212 )
2017
34
Constrictive Pericarditis: A Practical Clinical Approach. ( 28062267 )
2017
35
Incidence and Prognosis of Pericarditis After ST-Elevation Myocardial Infarction (from the Acute Coronary Syndrome Israeli Survey 2000 to 2013 Registry Database). ( 29370922 )
2017
36
Constrictive Pericarditis. ( 29025545 )
2017
37
Pericarditis caused by Campylobacter fetus subspecies fetus associated with ingestion of raw beef liver. ( 28803866 )
2017
38
Uremic pericarditis, pericardial effusion, and constrictive pericarditis in end-stage renal disease: Insights and pathophysiology. ( 28873222 )
2017
39
Purulent pericarditis complicating cardiac tamponade in a uremic patient caused by Staphylococcus aureus. ( 29108782 )
2017
40
Effusive-Constrictive Pericarditis. ( 29025546 )
2017
41
Treatment of Adults with Idiopathic Recurrent Pericarditis: Novel Use of Immunotherapy. ( 28079270 )
2017
42
The Therapeutic Role of Interleukin-1 Inhibition in Idiopathic Recurrent Pericarditis: Current Evidence and Future Challenges. ( 28660191 )
2017
43
Rheumatic Fever Presenting as Recurrent Pericarditis and Cardiac Tamponade. ( 28720034 )
2017
44
Seasonal patterns of acute and recurrent idiopathic pericarditis. ( 28914972 )
2017
45
A case of spontaneous purulent granulomatous pericarditis in a beagle. ( 28798534 )
2017
46
A Rare Case of Pneumopericardium in the Setting of Tuberculous Constrictive Pericarditis. ( 28634555 )
2017
47
Tuberculous pericarditis treated with steroid in a dialysis patient. ( 28765186 )
2017
48
New Cardiac Imaging Algorithms to Diagnose Constrictive Pericarditis Versus Restrictive Cardiomyopathy. ( 28405937 )
2017
49
A Case of Primary Bacterial Pericarditis with Recurrent Cardiac Tamponade. ( 28724847 )
2017
50
Surgical Treatment of Constrictive Pericarditis. ( 28461794 )
2017

Variations for Pericarditis

Expression for Pericarditis

Search GEO for disease gene expression data for Pericarditis.

Pathways for Pericarditis

Pathways related to Pericarditis according to GeneCards Suite gene sharing:

(show all 47)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.31 HRH4 IL1B IL6 IRAK4 TNF TNFRSF1A
2
Show member pathways
12.87 IL1B IL6 IRAK4 MEFV TNF
3
Show member pathways
12.69 IL1B IL6 IRAK4 TNF TNFRSF1A
4
Show member pathways
12.57 IL1B TNF TNFRSF1A TRAF3IP2
5
Show member pathways
12.57 IL1B IL6 IRAK4 TNF TNFRSF1A
6 12.48 IL1B IRAK4 TNF TNFRSF1A
7
Show member pathways
12.32 IL1B IL6 IRAK4 TNF TNFRSF1A
8
Show member pathways
12.25 CRP IL1B IL6 TNF
9
Show member pathways
12.24 IL1B IL6 TNF TRAF3IP2
10
Show member pathways
12.16 IL1B IRAK4 TNF TNFRSF1A
11
Show member pathways
12.14 IL1B IL6 IRAK4 TNF
12
Show member pathways
12.07 IL1B IL6 TNF
13
Show member pathways
12.05 IL1B IL6 IRAK4 TNF
14 12.01 IL1B TNF TNFRSF1A
15 11.97 IL1B TNF TNFRSF1A
16 11.94 IL1B IL6 TNF
17 11.91 IL1B IL6 TNF
18
Show member pathways
11.88 IL6 TNF TNFRSF1A
19
Show member pathways
11.86 IL1B IL6 TNF
20 11.83 IL1B IL6 TNF
21 11.81 IL1B IL6 TNF
22 11.8 IL1B IL6 TNF
23 11.77 IL1B IL6 TNF
24 11.74 IL1B IL6 TNF TNFRSF1A
25 11.68 IL1B IL6 TNF
26 11.65 IRAK4 TNF TNFRSF1A
27 11.65 IL1B IRAK4 TNF TNFRSF1A
28 11.61 IL1B IL6 IRAK4 TNF TNFRSF1A
29 11.6 IL1B IL6 TNF
30 11.51 IL1B IL6 TNF
31 11.48 IL6 TNF TNFRSF1A
32 11.44 IL1B IL6 TNF
33 11.44 IL1B IL6 IRAK4 TNF
34 11.4 IL1B IL6 TNF
35
Show member pathways
11.26 IL1B IL6 TNF TNFRSF1A
36 11.24 IL1B IL6 TNF
37 11.23 IL1B IL6 TNF
38 11.18 IL1B IL6 TNF
39 11.14 IL1B IL6 TNF
40 11.11 IL1B IL6 TNF
41 11.06 TNF TNFRSF1A
42 11.04 IL1B TNF
43 11.04 IL6 TNF
44 10.88 IL1B TNF
45 10.78 CRP IL6 TNF
46 10.73 IL1B IL6
47 10.61 IL1B IL6 TNF TNFRSF1A

GO Terms for Pericarditis

Cellular components related to Pericarditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.23 ADA CRP IL1B IL6 IRAK4 NPPB

Biological processes related to Pericarditis according to GeneCards Suite gene sharing:

(show all 28)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.93 CRP IL1B IL6 TNF
2 immune response GO:0006955 9.89 IL1B IL6 PRG4 TNF TNFRSF1A
3 positive regulation of DNA binding transcription factor activity GO:0051091 9.77 IL1B IL6 TNF
4 defense response to Gram-positive bacterium GO:0050830 9.76 CRP IL6 TNF
5 negative regulation of inflammatory response GO:0050728 9.75 ADA MEFV TNFRSF1A
6 positive regulation of smooth muscle cell proliferation GO:0048661 9.7 IL6 IRAK4 TNF
7 humoral immune response GO:0006959 9.69 IL6 TNF TRAF3IP2
8 cytokine-mediated signaling pathway GO:0019221 9.67 IL1B IL6 IRAK4 TNFRSF1A
9 positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 9.65 IL1B IRAK4 TNF TNFRSF1A TRAF3IP2
10 positive regulation of NF-kappaB import into nucleus GO:0042346 9.64 IL1B TNF
11 positive regulation of chemokine production GO:0032722 9.63 IL6 TNF
12 positive regulation of interleukin-6 production GO:0032755 9.63 IL1B IL6 TNF
13 embryonic digestive tract development GO:0048566 9.62 ADA TNF
14 negative regulation of lipid catabolic process GO:0050995 9.62 IL1B TNF
15 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.62 IL1B IL6 IRAK4 TNF
16 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.61 IL1B TNF
17 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.61 IL1B TNF
18 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.59 IL1B TNF
19 neutrophil mediated immunity GO:0002446 9.57 IL6 IRAK4
20 positive regulation of ceramide biosynthetic process GO:2000304 9.56 TNF TNFRSF1A
21 positive regulation of chemokine biosynthetic process GO:0045080 9.55 IL1B TNF
22 death-inducing signaling complex assembly GO:0071550 9.54 TNF TNFRSF1A
23 positive regulation of fever generation GO:0031622 9.48 IL1B TNF
24 sequestering of triglyceride GO:0030730 9.43 IL1B TNF
25 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.4 IL1B TNF
26 negative regulation of lipid storage GO:0010888 9.33 CRP IL6 TNF
27 inflammatory response GO:0006954 9.17 CRP HRH4 IL1B IL6 MEFV TNF
28 regulation of establishment of endothelial barrier GO:1903140 9.13 IL1B TNF TNFRSF1A

Molecular functions related to Pericarditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 interleukin-1 receptor binding GO:0005149 8.62 IL1B IRAK4

Sources for Pericarditis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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