MCID: PRC013
MIFTS: 53

Pericarditis malady

Cardiovascular diseases, Rare diseases categories
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Summaries for Pericarditis

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Disease Ontology:8 A pericardium disease that is characterized by an inflammation of the pericardium and has symptom chest pain.

MalaCards based summary: Pericarditis is related to constrictive pericarditis and pericardial effusion, and has symptoms including An important gene associated with Pericarditis is PRG4 (proteoglycan 4), and among its related pathways is IL-9 Signaling Pathways. The compounds niacin and nicotinamide have been mentioned in the context of this disorder. Affiliated tissues include heart, liver and lung, and related mouse phenotypes are skeleton and hematopoietic system.

Wikipedia:65 Pericarditis is an inflammation of the pericardium (the fibrous sac surrounding the heart). A... more...

Aliases & Classifications for Pericarditis

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 48Orphanet, 62UMLS, 39NCIt, 34MeSH, 57SNOMED-CT, 35MESH via Orphanet, 26ICD10 via Orphanet, 63UMLS via Orphanet, 25ICD10
See all sources

Pericarditis, Aliases & Descriptions:

Name: Pericarditis 8 10 44 48 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Cardiovascular diseases


Characteristics (Orphanet epidemiological data):

48
pericarditis:
Inheritance: Sporadic; Age of onset: Variable


External Ids:

Disease Ontology8 DOID:1787
NCIt39 C34915
MeSH34 D010493
MESH via Orphanet35 D010493
SNOMED-CT57 3238004
ICD10 via Orphanet26 I01.0, I30.0, I30.1 I30.8, I30.9, more
UMLS via Orphanet63 C0031046, C0265143
ICD1025 I32, I32.8

Related Diseases for Pericarditis

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Diseases related to Pericarditis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 308)
idRelated DiseaseScoreTop Affiliating Genes
1constrictive pericarditis32.0NPPB, ADA
2pericardial effusion31.4ADA
3brucellosis30.3MEFV
4familial mediterranean fever30.2MEFV, TNFRSF1A
5behcet's disease29.9MEFV, ADA
6amyloidosis29.9TNFRSF1A, MEFV, NPPB
7acute myocardial infarction29.7NPPB, MEFV
8rheumatoid arthritis29.7TNFRSF1A, NAMPT, ADA, PRG4, MEFV
9noonan syndrome29.5NPPB, TNFRSF1A
10sepsis29.3TNFRSF1A, NAMPT, NPPB
11diabetes mellitus29.3TNFRSF1A, NAMPT, NPPB
12restrictive cardiomyopathy10.7
13cardiac tamponade10.6
14camptodactyly arthropathy coxa vara pericarditis syndrome10.5
15idiopathic recurrent pericarditis10.5
16arthritis10.5
17myocardial infarction10.4
18gestational diabetes10.4PRG4
19pneumonia10.4
20hemopericardium10.4
21palindromic rheumatism10.4MEFV
22myocarditis10.4
23aneurysm10.4
24arthropathy10.4
25tuberculosis10.4
26endocarditis10.3
27meningitis10.3
28pericardial mesothelioma10.3
29protein-losing enteropathy10.3
30chylous ascites10.3
31hepatitis10.3
32systemic lupus erythematosus10.3
33lupus erythematosus10.3
34mediastinitis10.3
35pericardial tuberculosis10.2
36leukemia10.2
37chronic rheumatic pericarditis10.2
38histoplasmosis pericarditis10.2
39mulibrey nanism10.2
40dressler's syndrome10.2
41aortic aneurysm10.2
42influenza10.2
43mycobacterium kansasii10.2
44meningococcal meningitis10.2
45pleurisy10.2MEFV, ADA
46inferior myocardial infarction10.1
47melioidosis10.1
48acute myocarditis10.1
49esophagitis10.1
50vasculitis10.1

Graphical network of the top 20 diseases related to Pericarditis:



Diseases related to pericarditis

Symptoms for Pericarditis

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Drugs & Therapeutics for Pericarditis

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Drug clinical trials:

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Genetic Tests for Pericarditis

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Anatomical Context for Pericarditis

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MalaCards organs/tissues related to Pericarditis:

32
Heart, Liver, Lung, Bone, Bone marrow, Testes, Brain, Kidney, Thyroid, Breast, Lymph node, Myeloid, T cells, B cells

Animal Models for Pericarditis or affiliated genes

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MGI Mouse Phenotypes related to Pericarditis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053908.2MEFV, PRG4, ADA, TNFRSF1A
2MP:00053978.2MEFV, ADA, NAMPT, TNFRSF1A
3MP:00107687.4TNFRSF1A, NAMPT, ADA, PRG4, MEFV

Publications for Pericarditis

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Articles related to Pericarditis:

(show top 50)    (show all 1044)
idTitleAuthorsYear
1
Constrictive pericarditis--a curable diastolic heart failure. (25072910)
2014
2
Idiopathic pericarditis and pericardial effusion in children: contemporary epidemiology and management. (25380671)
2014
3
Successful Treatment of Severe Right-Sided Heart Failure Due to Postoperative Constrictive Pericarditis With Tolvaptan. (25343308)
2014
4
Cardiac tamponade with community-acquired methicillin-resistant Staphylococcus aureus pericarditis. (23903515)
2013
5
Constrictive pericarditis with a calcific mass invading into the right ventricular myocardium. (23190384)
2013
6
Constrictive pericarditis with intrapericardial abscess. (23207988)
2013
7
Pericarditis, myocarditis, and other cardiomyopathies. (23402470)
2013
8
Percutaneous intrapericardial injection of triamcinolone in a patient with incessant pericarditis: a novel technique. (23148999)
2013
9
Purulent pericarditis caused by a bad tooth. (23344978)
2013
10
Cholesterol pericarditis without active inflammatory change: Evaluation by positron emission tomography and computed tomography. (24155084)
2013
11
Constrictive pericarditis developed after childhood repair of ventricular septal defect. (23910801)
2013
12
Outcome of pericardiectomy for constrictive pericarditis in Japan: a nationwide outcome study. (23791164)
2013
13
Mycobacterium kansasii pericarditis in a kidney transplant recipient: a case report and comprehensive review of the literature. (22823928)
2012
14
Clues to detect tumor necrosis factor receptor-associated periodic syndrome (TRAPS) among patients with idiopathic recurrent acute pericarditis: results of a multicentre study. (22311714)
2012
15
IL-33 independently induces eosinophilic pericarditis and cardiac dilation: ST2 improves cardiac function. (22454393)
2012
16
Annular velocities in constrictive pericarditis: annulus and beyond. (21679890)
2011
17
Pneumococcal pneumonia complicating purulent pericarditis in a previously healthy girl: a rare yet possible fatal complication in the antibiotic era. (21822088)
2011
18
Azathioprine in isolated recurrent pericarditis: a single centre experience. (21296434)
2011
19
Constrictive pericarditis with extensive calcification. (21308337)
2011
20
Purulent pericarditis and pericardial abscess one year after LAD-stenting. (21591586)
2011
21
Noninvasive imaging techniques of constrictive pericarditis. (20828356)
2010
22
Recurrent pericarditis caused by a rare mutation in the TNFRSF1A gene and with excellent response to anakinra treatment. (21029567)
2010
23
Pericarditis as a rare complication of pneumococcal pneumonia in a young infant. (20666278)
2010
24
Purulent pericarditis due to Streptococcus pneumoniae diagnosed by pneumococcal urinary antigen assay and 16S rDNA sequence of the pericardial fluid. (20686309)
2010
25
Acute pericarditis and transient erythroblastopenia associated with human parvovirus B19 infection. (21200105)
2010
26
Transient constrictive pericarditis: an elusive diagnosis. (21142635)
2010
27
Hemorrhagic Pericarditis in a child with primary varicella infection (chickenpox). (19332925)
2009
28
Transient constrictive pericarditis diagnosed by cardiac magnetic resonance, 67Ga scintigraphy, and positron emission tomography. (19467563)
2009
29
Purulent pericarditis complicated by cardiac tamponade secondary to a hydatid cyst-associated hepatic abscess. (19706257)
2009
30
Fatal chylous ascites, pericarditis and extensive venous thrombosis, due to an aggressive T cell non-Hodgkin lymphoma. (18679682)
2009
31
Role of echocardiography in the diagnosis of constrictive pericarditis. (19130999)
2009
32
Infective mycotic aneurysm presenting as transient acute coronary occlusion and infectious pericarditis. (19434042)
2009
33
A rare cause of constrictive pericarditis: primary cardiac lymphoma. (17363082)
2008
34
Constrictive pericarditis at abdominal CT: a commonly overlooked diagnosis. (17510764)
2008
35
Tuberculous effusive-constrictive pericarditis. (18776964)
2008
36
Impact of left ventricular function on immediate and long-term outcomes after pericardiectomy in constrictive pericarditis. (19026793)
2008
37
Cystic tuberculous constrictive pericarditis. (17638949)
2007
38
Acute suppurative thyroiditis extending to descending necrotizing mediastinitis and pericarditis. (17381365)
2007
39
Longitudinal mitral annular early diastolic velocities in differentiating effusive constrictive pericarditis from restrictive cardiomyopathy: a case with extreme and straddling variations in regional velocities. (19122257)
2007
40
Adenosine deaminase and tuberculous pericarditis--a systematic review with meta-analysis. (16950165)
2006
41
Magnetic resonance imaging of effusive constrictive pericarditis. (16521660)
2005
42
Constrictive pericarditis following cat-scratch disease in a 12-year-old female: a rare association. (14635359)
2003
43
Constrictive pericarditis caused by calcification and organized hematoma 30 years after cardiac surgery. (12074283)
2002
44
Constrictive pericarditis in the modern era: a diagnostic dilemma. (11711451)
2001
45
Autonomic functions in restrictive cardiomyopathy and constrictive pericarditis: a comparison. (9736135)
1998
46
Images in cardiovascular medicine. Constrictive pericarditis. (9264516)
1997
47
Pericardiectomy after two decades of constrictive pericarditis in a patient with chronic renal failure. (8592610)
1995
48
Clotted hemopericardium with the hemodynamic characteristics of constrictive pericarditis. (7355745)
1980
49
Recognition and treatment of hemopericardium and hemorrhagic pericarditis by pericardiotomy. (13636482)
1959
50
Pericarditis due to a mycotic aneurysm in subacute bacterial endocarditis; report of a case affecting congenitally stenosed quadricuspid aortic valve. (13524719)
1958

Variations for Pericarditis

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Expression for genes affiliated with Pericarditis

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Expression patterns in normal tissues for genes affiliated with Pericarditis

Search GEO for disease gene expression data for Pericarditis.

Pathways for genes affiliated with Pericarditis

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Pathways related to Pericarditis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
IL-9 Signaling Pathway37
Development Thrombopoietin regulated cell processes60
IL-7 Signaling Pathway37
Immune response IL 9 signaling pathway60
9.1NAMPT, TNFRSF1A

Compounds for genes affiliated with Pericarditis

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Compounds related to Pericarditis according to GeneCards/GeneDecks:

(show all 29)
idCompoundScoreTop Affiliating Genes
1niacin44 1110.8ADA, NAMPT
2nicotinamide44 1110.8ADA, NAMPT
3milrinone44 28 1111.8ADA, NPPB
4cilostazol44 1110.8NPPB, ADA
5allopurinol44 50 1111.8ADA, NPPB
6dipyridamole44 61 28 1112.7ADA, NPPB
7pioglitazone28 44 50 1112.6NPPB, NAMPT
8deoxyguanosine44 2410.6ADA, TNFRSF1A
9vincristine44 50 1111.5NPPB, ADA
10neopterin449.5TNFRSF1A, ADA
11mevalonate449.4MEFV, TNFRSF1A
12polyethylene glycol449.4ADA, TNFRSF1A
13colchicine44 61 2 28 1113.4MEFV, TNFRSF1A
14p005449.3NPPB, TNFRSF1A
15rosiglitazone28 44 50 24 1113.2NPPB, NAMPT
16p003449.2TNFRSF1A, NPPB
17carbachol44 28 1111.1NPPB, ADA
18p002449.0TNFRSF1A, NPPB
19indomethacin44 28 61 1111.9NPPB, ADA, TNFRSF1A
20norepinephrine44 24 1110.9NPPB, ADA, TNFRSF1A
21doxorubicin44 50 1110.9NPPB, ADA, TNFRSF1A
22forskolin44 50 1110.9TNFRSF1A, ADA, NPPB
23cyclosporin a44 28 6110.9NPPB, ADA, TNFRSF1A
24dopamine44 28 24 1111.9NPPB, ADA, TNFRSF1A
25vegf448.7NPPB, ADA, TNFRSF1A
26phosphatidylinositol448.6TNFRSF1A, NAMPT, NPPB
27estrogen448.6NPPB, ADA, TNFRSF1A
28creatinine448.4NPPB, ADA, NAMPT, TNFRSF1A
29dexamethasone44 50 28 1111.4NPPB, ADA, NAMPT, TNFRSF1A

GO Terms for genes affiliated with Pericarditis

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Cellular components related to Pericarditis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056157.6NPPB, PRG4, ADA, NAMPT, TNFRSF1A

Biological processes related to Pericarditis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to hypoxiaGO:0016669.2ADA, TNFRSF1A
2negative regulation of inflammatory responseGO:0507288.4MEFV, ADA, TNFRSF1A

Products for genes affiliated with Pericarditis

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Sources for Pericarditis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet