MCID: PRC013
MIFTS: 45

Pericarditis malady

Cardiovascular diseases, Rare diseases categories

Aliases & Classifications for Pericarditis

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Sources:
9Disease Ontology, 11DISEASES, 43Novoseek, 47Orphanet, 60UMLS, 55SNOMED-CT, 33MeSH, 38NCIt, 34MESH via Orphanet, 26ICD10 via Orphanet, 61UMLS via Orphanet, 25ICD10
See all sources

Pericarditis, Aliases & Descriptions:

Name: Pericarditis 9 11 43 47 60


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Cardiovascular diseases


Characteristics (Orphanet epidemiological data):

47
pericarditis:
Inheritance: Not applicable; Age of onset: All ages


External Ids:

Disease Ontology9 DOID:1787
MeSH33 D010493
NCIt38 C34915
Orphanet47 58208
SNOMED-CT55 3238004
MESH via Orphanet34 D010493
ICD10 via Orphanet26 I01.0, I30.0, I30.1 I30.8, I30.9, more
UMLS via Orphanet61 C0031046, C0265143
ICD1025 I32, I32.8

Summaries for Pericarditis

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Disease Ontology:9 A pericardium disease that is characterized by an inflammation of the pericardium and has symptom chest pain.

MalaCards based summary: Pericarditis is related to constrictive pericarditis and pericardial effusion, and has symptoms including chest pain An important gene associated with Pericarditis is PRG4 (proteoglycan 4), and among its related pathways is IL-9 Signaling Pathways. The compounds niacin and nicotinamide have been mentioned in the context of this disorder. Affiliated tissues include heart, liver and lung, and related mouse phenotypes are skeleton and hematopoietic system.

Wikipedia:63 Pericarditis is an inflammation of the pericardium (the fibrous sac surrounding the heart). A... more...

Related Diseases for Pericarditis

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Diseases related to Pericarditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 291)
idRelated DiseaseScoreTop Affiliating Genes
1constrictive pericarditis32.0NPPB, ADA
2pericardial effusion31.4ADA
3brucellosis30.3MEFV
4familial mediterranean fever, ar29.9MEFV, TNFRSF1A
5behcet's disease29.9MEFV, ADA
6amyloidosis29.9TNFRSF1A, MEFV, NPPB
7peritonitis29.8MEFV, ADA
8coronary artery disease29.7TNFRSF1A, NPPB
9acute myocardial infarction29.7NPPB, MEFV
10rheumatoid arthritis29.7TNFRSF1A, NAMPT, ADA, PRG4, MEFV
11restrictive cardiomyopathy10.7
12cardiac tamponade10.6
13camptodactyly-arthropathy-coxa vara-pericarditis syndrome10.6
14idiopathic recurrent pericarditis10.5
15arthritis10.5
16myocardial infarction10.4
17hemopericardium10.4
18myocarditis10.4
19pneumonia10.4
20mody, type ii10.4PRG4
21aneurysm10.4
22palindromic rheumatism10.4MEFV
23arthropathy10.4
24tuberculosis10.4
25mesothelioma10.4
26endocarditis10.3
27meningitis10.3
28pericardial mesothelioma10.3
29systemic lupus erythematosus10.3
30hepatitis10.3
31protein-losing enteropathy10.3
32atrial fibrillation10.3
33mediastinitis10.3
34chylous ascites10.3
35lupus erythematosus10.3
36chronic rheumatic pericarditis10.2
37histoplasmosis pericarditis10.2
38influenza10.2
39mulibrey nanism10.2
40leukemia10.2
41dressler's syndrome10.2
42aortic aneurysm10.2
43mycobacterium kansasii10.2
44meningococcal meningitis10.2
45pleurisy10.1MEFV, ADA
46melioidosis10.1
47pericardial tuberculosis10.1
48inferior myocardial infarction10.1
49acute myocarditis10.1
50esophagitis10.1

Graphical network of the top 20 diseases related to Pericarditis:



Diseases related to pericarditis

Symptoms for Pericarditis

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Symptoms:

 9
  • chest pain

Drugs & Therapeutics for Pericarditis

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Drug clinical trials:

Search ClinicalTrials for Pericarditis

Search NIH Clinical Center for Pericarditis

Genetic Tests for Pericarditis

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Anatomical Context for Pericarditis

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MalaCards organs/tissues related to Pericarditis:

31
Heart, Liver, Lung, Bone, Bone marrow, Testes, Brain, Kidney, Thyroid, Breast, Lymph node, Myeloid, T cells, B cells

Animal Models for Pericarditis or affiliated genes

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MGI Mouse Phenotypes related to Pericarditis:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053908.2MEFV, PRG4, ADA, TNFRSF1A
2MP:00053978.2MEFV, ADA, NAMPT, TNFRSF1A
3MP:00107687.4TNFRSF1A, NAMPT, ADA, PRG4, MEFV

Publications for Pericarditis

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Articles related to Pericarditis:

(show top 50)    (show all 1077)
idTitleAuthorsYear
1
Pericarditis in a 56-year-old female with Hashimoto's disease. (25791974)
2015
2
Giant Purulent Pericarditis with Cardiac Tamponade Due to Streptococcus intermedius Rapidly Progressing to Constriction. (25735951)
2015
3
Staphylococcal infection-related constrictive pericarditis with formation of a mycotic aneurysm in the right coronary artery. (25660915)
2015
4
Constrictive pericarditis--a curable diastolic heart failure. (25072910)
2014
5
Idiopathic pericarditis and pericardial effusion in children: contemporary epidemiology and management. (25380671)
2014
6
Successful Treatment of Severe Right-Sided Heart Failure Due to Postoperative Constrictive Pericarditis With Tolvaptan. (25343308)
2014
7
Cardiac tamponade with community-acquired methicillin-resistant Staphylococcus aureus pericarditis. (23903515)
2013
8
Constrictive pericarditis with a calcific mass invading into the right ventricular myocardium. (23190384)
2013
9
Constrictive pericarditis with intrapericardial abscess. (23207988)
2013
10
Pericarditis, myocarditis, and other cardiomyopathies. (23402470)
2013
11
Percutaneous intrapericardial injection of triamcinolone in a patient with incessant pericarditis: a novel technique. (23148999)
2013
12
Purulent pericarditis caused by a bad tooth. (23344978)
2013
13
Cholesterol pericarditis without active inflammatory change: Evaluation by positron emission tomography and computed tomography. (24155084)
2013
14
Constrictive pericarditis developed after childhood repair of ventricular septal defect. (23910801)
2013
15
Mycobacterium kansasii pericarditis in a kidney transplant recipient: a case report and comprehensive review of the literature. (22823928)
2012
16
Clues to detect tumor necrosis factor receptor-associated periodic syndrome (TRAPS) among patients with idiopathic recurrent acute pericarditis: results of a multicentre study. (22311714)
2012
17
IL-33 independently induces eosinophilic pericarditis and cardiac dilation: ST2 improves cardiac function. (22454393)
2012
18
Annular velocities in constrictive pericarditis: annulus and beyond. (21679890)
2011
19
Pneumococcal pneumonia complicating purulent pericarditis in a previously healthy girl: a rare yet possible fatal complication in the antibiotic era. (21822088)
2011
20
Azathioprine in isolated recurrent pericarditis: a single centre experience. (21296434)
2011
21
Noninvasive imaging techniques of constrictive pericarditis. (20828356)
2010
22
Recurrent pericarditis caused by a rare mutation in the TNFRSF1A gene and with excellent response to anakinra treatment. (21029567)
2010
23
Pericarditis as a rare complication of pneumococcal pneumonia in a young infant. (20666278)
2010
24
Purulent pericarditis due to Streptococcus pneumoniae diagnosed by pneumococcal urinary antigen assay and 16S rDNA sequence of the pericardial fluid. (20686309)
2010
25
Acute pericarditis and transient erythroblastopenia associated with human parvovirus B19 infection. (21200105)
2010
26
Transient constrictive pericarditis: an elusive diagnosis. (21142635)
2010
27
Hemorrhagic Pericarditis in a child with primary varicella infection (chickenpox). (19332925)
2009
28
Transient constrictive pericarditis diagnosed by cardiac magnetic resonance, 67Ga scintigraphy, and positron emission tomography. (19467563)
2009
29
Purulent pericarditis complicated by cardiac tamponade secondary to a hydatid cyst-associated hepatic abscess. (19706257)
2009
30
Fatal chylous ascites, pericarditis and extensive venous thrombosis, due to an aggressive T cell non-Hodgkin lymphoma. (18679682)
2009
31
Role of echocardiography in the diagnosis of constrictive pericarditis. (19130999)
2009
32
Infective mycotic aneurysm presenting as transient acute coronary occlusion and infectious pericarditis. (19434042)
2009
33
A rare cause of constrictive pericarditis: primary cardiac lymphoma. (17363082)
2008
34
Constrictive pericarditis at abdominal CT: a commonly overlooked diagnosis. (17510764)
2008
35
Tuberculous effusive-constrictive pericarditis. (18776964)
2008
36
Impact of left ventricular function on immediate and long-term outcomes after pericardiectomy in constrictive pericarditis. (19026793)
2008
37
Cystic tuberculous constrictive pericarditis. (17638949)
2007
38
Acute suppurative thyroiditis extending to descending necrotizing mediastinitis and pericarditis. (17381365)
2007
39
Longitudinal mitral annular early diastolic velocities in differentiating effusive constrictive pericarditis from restrictive cardiomyopathy: a case with extreme and straddling variations in regional velocities. (19122257)
2007
40
Adenosine deaminase and tuberculous pericarditis--a systematic review with meta-analysis. (16950165)
2006
41
Magnetic resonance imaging of effusive constrictive pericarditis. (16521660)
2005
42
Constrictive pericarditis following cat-scratch disease in a 12-year-old female: a rare association. (14635359)
2003
43
Constrictive pericarditis caused by calcification and organized hematoma 30 years after cardiac surgery. (12074283)
2002
44
Constrictive pericarditis in the modern era: a diagnostic dilemma. (11711451)
2001
45
Autonomic functions in restrictive cardiomyopathy and constrictive pericarditis: a comparison. (9736135)
1998
46
Pericardiectomy after two decades of constrictive pericarditis in a patient with chronic renal failure. (8592610)
1995
47
Hepatic coma as a presenting feature of constrictive pericarditis. (8438853)
1993
48
Clotted hemopericardium with the hemodynamic characteristics of constrictive pericarditis. (7355745)
1980
49
Recognition and treatment of hemopericardium and hemorrhagic pericarditis by pericardiotomy. (13636482)
1959
50
Pericarditis due to a mycotic aneurysm in subacute bacterial endocarditis; report of a case affecting congenitally stenosed quadricuspid aortic valve. (13524719)
1958

Variations for Pericarditis

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Expression for genes affiliated with Pericarditis

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Search GEO for disease gene expression data for Pericarditis.

Pathways for genes affiliated with Pericarditis

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Pathways related to Pericarditis according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
IL-9 Signaling Pathway36
Development Thrombopoietin regulated cell processes58
IL-7 Signaling Pathway36
Immune response IL 9 signaling pathway58
9.1NAMPT, TNFRSF1A

Compounds for genes affiliated with Pericarditis

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Compounds related to Pericarditis according to GeneCards Suite gene sharing:

(show all 29)
idCompoundScoreTop Affiliating Genes
1niacin43 1210.8ADA, NAMPT
2nicotinamide43 1210.8ADA, NAMPT
3milrinone43 28 1211.8ADA, NPPB
4cilostazol43 1210.8NPPB, ADA
5allopurinol43 49 1211.8ADA, NPPB
6dipyridamole43 59 28 1212.7ADA, NPPB
7pioglitazone28 43 49 1212.6NPPB, NAMPT
8deoxyguanosine43 2410.6ADA, TNFRSF1A
9vincristine43 49 1211.5NPPB, ADA
10neopterin439.5TNFRSF1A, ADA
11mevalonate439.4MEFV, TNFRSF1A
12polyethylene glycol439.4ADA, TNFRSF1A
13colchicine43 59 2 28 1213.4MEFV, TNFRSF1A
14p005439.3NPPB, TNFRSF1A
15rosiglitazone28 43 49 24 1213.2NPPB, NAMPT
16p003439.2TNFRSF1A, NPPB
17carbachol43 28 1211.1NPPB, ADA
18p002439.0TNFRSF1A, NPPB
19indomethacin43 28 59 1211.9NPPB, ADA, TNFRSF1A
20norepinephrine43 24 1210.9NPPB, ADA, TNFRSF1A
21doxorubicin43 49 1210.9NPPB, ADA, TNFRSF1A
22forskolin43 49 1210.9TNFRSF1A, ADA, NPPB
23cyclosporin a43 28 5910.9NPPB, ADA, TNFRSF1A
24dopamine43 28 24 1211.9NPPB, ADA, TNFRSF1A
25vegf438.7NPPB, ADA, TNFRSF1A
26phosphatidylinositol438.6TNFRSF1A, NAMPT, NPPB
27estrogen438.6NPPB, ADA, TNFRSF1A
28creatinine438.4NPPB, ADA, NAMPT, TNFRSF1A
29dexamethasone43 49 28 1211.4NPPB, ADA, NAMPT, TNFRSF1A

GO Terms for genes affiliated with Pericarditis

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Cellular components related to Pericarditis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056157.6NPPB, PRG4, ADA, NAMPT, TNFRSF1A

Biological processes related to Pericarditis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1response to hypoxiaGO:00016669.2ADA, TNFRSF1A
2negative regulation of inflammatory responseGO:00507288.4MEFV, ADA, TNFRSF1A

Products for genes affiliated with Pericarditis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Pericarditis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet