MCID: PRC013
MIFTS: 50

Pericarditis

Categories: Cardiovascular diseases

Aliases & Classifications for Pericarditis

MalaCards integrated aliases for Pericarditis:

Name: Pericarditis 12 29 52 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:1787
MeSH 42 D010493
NCIt 47 C34915
SNOMED-CT 64 3238004
ICD10 33 I32 I32.8
UMLS 69 C0031046

Summaries for Pericarditis

Disease Ontology : 12 A pericardium disease that is characterized by an inflammation of the pericardium and has symptom chest pain.

MalaCards based summary : Pericarditis is related to arthropathy and cutaneous leishmaniasis. An important gene associated with Pericarditis is PRG4 (Proteoglycan 4), and among its related pathways/superpathways are Akt Signaling and Toll-Like receptor Signaling Pathways. The drugs Coal tar and Colchicine have been mentioned in the context of this disorder. Affiliated tissues include heart, liver and lung, and related phenotypes are cardiovascular system and hematopoietic system

Wikipedia : 72 Pericarditis is inflammation of the pericardium (the fibrous sac surrounding the heart). Symptoms... more...

Related Diseases for Pericarditis

Diseases related to Pericarditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 459)
id Related Disease Score Top Affiliating Genes
1 arthropathy 30.7 ADA CRP
2 cutaneous leishmaniasis 29.8 IL6 TNF
3 chickenpox 29.7 CRP MEFV TNF
4 primary biliary cirrhosis 29.6 IL6 TNF TNFRSF1A
5 lymphoma 29.4 IL1B IL6 MEFV TNF
6 cataract 29.3 IL1B TNF
7 rheumatoid arthritis 29.0 CRP IL1B IL6 TNF TNFRSF1A
8 asbestosis 29.0 IL1B IL6 TNF
9 myocardial infarction 28.1 CRP IL1B IL6 NPPB TNF TNNT2
10 camptodactyly-arthropathy-coxa vara-pericarditis syndrome 12.4
11 constrictive pericarditis 12.3
12 idiopathic recurrent pericarditis 12.1
13 histoplasmosis pericarditis 11.9
14 chronic rheumatic pericarditis 11.9
15 pericardial tuberculosis 11.5
16 dressler's syndrome 11.3
17 mulibrey nanism 11.2
18 acute neonatal citrullinemia type i 10.8 MEFV TNFRSF1A
19 acute megakaryoblastic leukemia without down syndrome 10.8 MEFV TNFRSF1A
20 end stage renal failure 10.8
21 systemic onset juvenile idiopathic arthritis 10.8
22 chronic kidney failure 10.8
23 leigh syndrome with leukodystrophy 10.7 MEFV TNFRSF1A
24 collagenopathy type 2 alpha 1 10.7 CRP IL6
25 urethral gland abscess 10.7 ADA CRP
26 crystal arthropathies 10.7 CRP IL6
27 shoulder impingement syndrome 10.7 CRP IL6
28 porokeratosis 3, multiple types 10.7 CRP TNFRSF1A
29 brachydactyly-distal symphalangism syndrome 10.6 CRP IL6
30 smarca4-deficient sarcoma of thorax 10.6 IL6 TNF
31 craniometaphyseal dysplasia 10.6 MEFV TNF
32 multiple epiphyseal dysplasia 10.6 TNF TNFRSF1A
33 aortic arch interruption 10.6 IL6 TNF
34 retinitis pigmentosa 75 10.6 TNF TNFRSF1A
35 erythema elevatum diutinum 10.6 CRP IL6
36 pyrimidine metabolic disorder 10.5 CRP MEFV PRG4
37 spirillary rat-bite fever 10.5 IL6 TNF
38 cataract congenital autosomal dominant 10.5 CRP IL6
39 toxoplasmosis 10.5 IL6 TNF
40 pneumoconiosis 10.5 ADA CRP IL6
41 dyslexia 5 10.5 IL6 TNF
42 vagina leiomyosarcoma 10.5 IL6 MEFV
43 euthyroid sick syndrome 10.5 CRP TNF
44 anencephaly and spina bifida x-linked 10.5 IL6 TNF
45 ciliary discoordination, due to random ciliary orientation 10.5 CRP NPPB
46 antigen-peptide-transporter 2 deficiency 10.5 IL6 TNF
47 partial central choroid dystrophy 10.4 CRP IL6 MEFV
48 chronic diarrhea due to guanylate cyclase 2c overactivity 10.4 CRP IL6
49 polyarteritis nodosa 10.4 ADA CRP TNF
50 papilledema 10.4 IL6 TNF

Graphical network of the top 20 diseases related to Pericarditis:



Diseases related to Pericarditis

Symptoms & Phenotypes for Pericarditis

MGI Mouse Phenotypes related to Pericarditis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.86 TNFRSF1A TNNT2 TRAF3IP2 ADA CRP IL1B
2 hematopoietic system MP:0005397 9.81 ADA HRH4 IL1B IL6 IRAK4 MEFV
3 homeostasis/metabolism MP:0005376 9.7 ADA CRP HRH4 IL1B IL6 IRAK4
4 immune system MP:0005387 9.32 MEFV TNF TNFRSF1A TRAF3IP2 ADA CRP

Drugs & Therapeutics for Pericarditis

Drugs for Pericarditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 45)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Coal tar Approved Phase 4,Phase 3 8007-45-2
2
Colchicine Approved Phase 4,Phase 3,Phase 2,Early Phase 1 64-86-8 6167 2833
3
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
4 Antimitotic Agents Phase 4,Phase 3,Phase 2,Early Phase 1
5 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Early Phase 1
6 Interleukin 1 Receptor Antagonist Protein Phase 4,Early Phase 1
7 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2
8 Peripheral Nervous System Agents Phase 4,Phase 3
9 Fibrinolytic Agents Phase 4,Phase 3
10 Analgesics Phase 4
11 Analgesics, Non-Narcotic Phase 4
12 Anti-Inflammatory Agents, Non-Steroidal Phase 4
13 Antipyretics Phase 4
14 Cyclooxygenase Inhibitors Phase 4
15 Platelet Aggregation Inhibitors Phase 4
16
Methylprednisolone Approved, Vet_approved Phase 3 83-43-2 6741
17
Prednisolone Approved, Vet_approved Phase 3 50-24-8 5755
18 Antiemetics Phase 3
19 Antineoplastic Agents, Hormonal Phase 3,Phase 2
20 Autonomic Agents Phase 3
21 Gastrointestinal Agents Phase 3
22 glucocorticoids Phase 3,Phase 2
23 Hormone Antagonists Phase 3,Phase 2
24 Hormones Phase 3,Phase 2
25 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2
26 Methylprednisolone acetate Phase 3
27 Methylprednisolone Hemisuccinate Phase 3
28 Neuroprotective Agents Phase 3
29 Prednisolone acetate Phase 3
30 Prednisolone hemisuccinate Phase 3
31 Prednisolone phosphate Phase 3
32 Protective Agents Phase 3
33 Vaccines Phase 3
34 Plasminogen Phase 3
35 Tissue Plasminogen Activator Phase 3
36
Abatacept Approved Phase 2 332348-12-6 10237
37
Prednisone Approved, Vet_approved Phase 2 53-03-2 5865
38
Eplerenone Approved Phase 2 107724-20-9 150310 443872
39 Immunosuppressive Agents Phase 2
40 Adrenergic beta-Antagonists Phase 2
41 Atorvastatin Calcium Phase 2 134523-03-8
42 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 2
43
Iron Approved 7439-89-6 23925
44
Cyclophosphamide Approved, Investigational 50-18-0, 6055-19-2 2907
45
Menthol Approved 2216-51-5 16666

Interventional clinical trials:

(show all 36)

id Name Status NCT ID Phase Drugs
1 Study of Colchicine to Treat and Prevent Recurrent Pericarditis After Failure of Conventional Treatment. Completed NCT00235079 Phase 4 Colchicine;Placebo
2 AnakInRa for Treatment of Recurrent Idiopathic Pericarditis (AIRTRIP) Completed NCT02219828 Phase 4 Anakinra;Placebo
3 Anti-inflammatory Effects of Colchicine in PCI Recruiting NCT01709981 Phase 4 Colchicine;Placebo
4 Benign Acute Pericarditis: Brief Versus Longer Treatment Using Aspirin Terminated NCT00946907 Phase 4 Aspirin;placebo
5 Study of Colchicine to Treat Acute Pericarditis and Prevent Recurrences Completed NCT00128453 Phase 3 Colchicine (for 3 months);Placebo
6 Study of Colchicine to Treat and Prevent Recurrent Pericarditis (First Episode) Completed NCT00128414 Phase 3 Colchicine (for 6 months);Placebo
7 A Trial of Adjunctive Prednisolone and Mycobacterium w Immunotherapy in Tuberculous Pericarditis Completed NCT00810849 Phase 3 Prednisolone
8 Study of Colchicine to Prevent the Postpericardiotomy Syndrome Completed NCT00128427 Phase 3 Colchicine (for 1 month)
9 IMPI 2 - A Trial of Intrapericardial Alteplase in Large Pericardial Effusion Recruiting NCT02673879 Phase 3
10 Myocardial Screening in Fetuses With Congenital Cytomegalovirus (CMV) Infection Not yet recruiting NCT02787382 Phase 3
11 Abatacept in the Treatment and Prevention of Active Systemic Lupus Erythematosus (SLE) Flares in Combination With Prednisone Completed NCT00119678 Phase 2 Abatacept;Placebo;Prednisone;Abatacept
12 Interest of COLchicine in the Treatment of Patients With Acute Myocardial INfarction and With Inflammatory Response Completed NCT02363725 Phase 2 Colchimax®;Conventional treatment
13 A Randomized Comparison of Radiation Therapy Techniques in the Management of Node Positive Breast Cancer Active, not recruiting NCT00581256 Phase 1, Phase 2
14 Noise, a Risk for Heart in Airplane Pilots Unknown status NCT01063582
15 Safety of Early Discharge Following Low Risk Myocardial Infarction Unknown status NCT01868256
16 Transient ECG Changes in Patients With Acute Biliary Disease Unknown status NCT01706068
17 ST Elevation in Acute Chest Pain; Could Measurement of Lipoprotein-associated Phospholipase A2 (Lp-PLA2) be Helpful to the Clinician? Completed NCT01041339
18 Apolipoprotein CIII Reduction Via Colchicine Completed NCT02083510 Early Phase 1 Colchicine
19 Epipericardial Fat Necrosis: A Misdiagnosed Condition Completed NCT01903980
20 Detection of Enterovirus RNA in Atheromatous Lesions Completed NCT00674531
21 Evaluation of Myocardial Iron Deposition in Patients of Heart Failure Using T2* MR Imaging Completed NCT02527330
22 Cardiovascular Diseases in HIV-infected Patients HIV-HEART Study: 7.5 Years Follow-up Completed NCT01667068
23 Cardiomyopathy Following Stem Cell Transplantation Completed NCT00352209
24 Cardiovascular Diseases in HIV-infected Patients HIV-HEART Study: 5 Years Follow-up Completed NCT01196273
25 Immunological Profile in Relation to Cardiac Geometry in Hypertension Completed NCT02165241
26 Prognostic Biomarkers in Patients With Acute Pericarditis Recruiting NCT02754713
27 Improvement of the Etiological Diagnosis of the Pericarditis Recruiting NCT02828085
28 ACAM2000® Myopericarditis Registry Active, not recruiting NCT01395082
29 Safety Surveillance Study of ACAM2000® Vaccinia Vaccine Active, not recruiting NCT00927719
30 A Survey of Hospitalizations in Cardiology Units in Sub-Saharan Africa Active, not recruiting NCT03231449
31 Treatment of Acute Pericarditis With Anakinra Not yet recruiting NCT03224585 Early Phase 1 Anakinra;Placebo
32 Septal Shift for the Diagnosis of COnstrictive Pericarditis: The Impact of Inspiratory Effort Quantification on Deep Breathing Manoeuvres Not yet recruiting NCT02685371
33 Management of Pericarditis in Children. Not yet recruiting NCT03253315
34 Feasibility Study of a Left Atrial Appendage Closure Device in Patients With Atrial Fibrillation Suspended NCT02583178
35 Constrictive Pericarditis in the Adult Congenital Cardiac Population Terminated NCT00268086
36 New Methods to Diagnose Constrictive Pericarditis Withdrawn NCT02027350

Search NIH Clinical Center for Pericarditis

Cochrane evidence based reviews: pericarditis

Genetic Tests for Pericarditis

Genetic tests related to Pericarditis:

id Genetic test Affiliating Genes
1 Pericarditis 29

Anatomical Context for Pericarditis

MalaCards organs/tissues related to Pericarditis:

39
Heart, Liver, Lung, Bone, Testes, Kidney, Bone Marrow

Publications for Pericarditis

Articles related to Pericarditis:

(show top 50) (show all 1268)
id Title Authors Year
1
Constrictive pericarditis-induced shunting through a PFO: Persistence despite pericardiectomy. ( 28649486 )
2017
2
The Therapeutic Role of Interleukin-1 Inhibition in Idiopathic Recurrent Pericarditis: Current Evidence and Future Challenges. ( 28660191 )
2017
3
Interventions for treating tuberculous pericarditis. ( 28902412 )
2017
4
Constrictive pericarditis from an endocardial pacemaker lead. ( 28710300 )
2017
5
Uremic pericarditis, pericardial effusion, and constrictive pericarditis in end-stage renal disease: Insights and pathophysiology. ( 28873222 )
2017
6
New Cardiac Imaging Algorithms to Diagnose Constrictive Pericarditis Versus Restrictive Cardiomyopathy. ( 28405937 )
2017
7
The Efficacy of Yttrium-90 Radiosynovectomy in Patients with Camptodactyly-Arthropathy-Coxa Vara-Pericarditis Syndrome. ( 28291008 )
2017
8
Streptococcus intermedius: An Unusual Case of Purulent Pericarditis. ( 28932608 )
2017
9
A case of spontaneous purulent granulomatous pericarditis in a beagle. ( 28798534 )
2017
10
Tuberculous pericarditis treated with steroid in a dialysis patient. ( 28765186 )
2017
11
Visualization of suppressed intraventricular flow by constrictive pericarditis. ( 28800477 )
2017
12
Acute Pericarditis: Descriptive Study and Etiology Determination in a Predominantly African American Population. ( 28924519 )
2017
13
Acute pneumonitis and pericarditis related to alemtuzumab therapy in relapsing-remitting multiple sclerosis. ( 27888417 )
2017
14
Serial semi-invasive hemodynamic assessment following pericardiectomy for chronic constrictive pericarditis. ( 28393776 )
2017
15
Effusive-Constrictive Pericarditis After Pericardiocentesis: Incidence, Associated Findings, and Natural History. ( 28917680 )
2017
16
Constrictive, Calcific Pericarditis in a Scleroderma Patient. ( 28937498 )
2017
17
Constrictive, Calcific Pericarditis in a Scleroderma Patient. ( 28937476 )
2017
18
Pericardiectomy for Constrictive Pericarditis: An Institution's 21 Years Experience. ( 28780766 )
2017
19
Rheumatic Fever Presenting as Recurrent Pericarditis and Cardiac Tamponade. ( 28720034 )
2017
20
Pericardial interstitial cell senescence responsible for pericardial structural remodeling in idiopathic and postsurgical constrictive pericarditis. ( 28456362 )
2017
21
Treatment of Adults with Idiopathic Recurrent Pericarditis: Novel Use of Immunotherapy. ( 28079270 )
2017
22
Incidence and Significance of Adhesions Encountered during Epicardial Mapping and Ablation of Ventricular Tachycardia in Patients with no History of Prior Cardiac Surgery or Pericarditis. ( 28917555 )
2017
23
Correction to: A Case of Rheumatic Fibrinous Pericarditis. ( 28069668 )
2017
24
Seasonal patterns of acute and recurrent idiopathic pericarditis. ( 28914972 )
2017
25
A Case of Primary Bacterial Pericarditis with Recurrent Cardiac Tamponade. ( 28724847 )
2017
26
Purulent Pericarditis with Salmonella enterica Subspecies arizona in a Patient with Type 2 Diabetes Mellitus. ( 28781305 )
2017
27
Idiopathic relapsing acute pericarditis: Report of one case with favorable response to anakinra. ( 28919212 )
2017
28
Pericarditis caused by Campylobacter fetus subspecies fetus associated with ingestion of raw beef liver. ( 28803866 )
2017
29
Consideration of atrial arrhythmias associated with cardiac tamponade and pericarditis. ( 28774768 )
2017
30
Localized constrictive pericarditis compressing and obstructing the right ventricular inflow tract due to a giant anterior calcified cardiac mass. A case report. ( 28886389 )
2017
31
Diagnosis of systemic inflammatory diseases among patients admitted for acute pericarditis with pericardial effusion. ( 28937580 )
2017
32
Large ventricular septal defect and coexisting chronic constrictive pericarditis: "reversible Eisenmenger syndrome"-5 years after corrective surgery. ( 28303664 )
2017
33
Multidrug Resistant Invasive Nontyphoidal Salmonella Isolated from and Masquerading Healed Tubercular Constrictive Pericarditis and Study of Virulence Markers. ( 28560124 )
2017
34
Constrictive Pericarditis: A Practical Clinical Approach. ( 28062267 )
2017
35
Transient constrictive pericarditis following acute idiopathic pericarditis. AA case report. ( 28827145 )
2017
36
Surgical Treatment of Constrictive Pericarditis. ( 28461794 )
2017
37
Rapidly growing coronary artery aneurysm associated with pericarditis. ( 28727582 )
2017
38
A Rare Case of Pneumopericardium in the Setting of Tuberculous Constrictive Pericarditis. ( 28634555 )
2017
39
Experience With Pericardiectomy for Constrictive Pericarditis Over Eight Decades. ( 28760468 )
2017
40
A clinical enigma of ongoing constrictive pericarditis. ( 28572226 )
2017
41
Major vessel venous thrombosis in patients of posttubercular chronic constrictive pericarditis undergoing pericardectomy: A rare scenario. ( 28701604 )
2017
42
Refractory idiopathic recurrent pericarditis: treatment with interleukin-1 receptor antagonist is an option! ( 28746150 )
2017
43
Usefulness of Novel Immunotherapeutic Strategies for Idiopathic Recurrent Pericarditis. ( 26742476 )
2016
44
IgG4-related effusive constrictive pericarditis. ( 27044912 )
2016
45
Potentially missed acute pericarditis: atypical pericarditis. ( 27663765 )
2016
46
Pleuritic chest pain from portal hypertensive gastropathy in ESRD patient with autosomal dominant polycystic kidney disease misdiagnosed as pericarditis. ( 27069969 )
2016
47
Development of Acute Pericarditis Associated with New-onset Rheumatoid Arthritis in a Diabetic Patient with Renal Impairment: The Elusive Nature of Uremia. ( 27086811 )
2016
48
Carcinomatous pleuritis and pericarditis accompanied by pulmonary tuberculosis. ( 28031837 )
2016
49
Pericarditis Caused by Hyperinvasive Strain of Neisseria meningitidis, Sardinia, Italy, 2015. ( 27191370 )
2016
50
Transient Constrictive Pericarditis: Current Diagnostic and Therapeutic Strategies. ( 26995404 )
2016

Variations for Pericarditis

Expression for Pericarditis

Search GEO for disease gene expression data for Pericarditis.

Pathways for Pericarditis

Pathways related to Pericarditis according to GeneCards Suite gene sharing:

(show all 46)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.31 HRH4 IL1B IL6 IRAK4 TNF TNFRSF1A
2
Show member pathways
12.88 IL1B IL6 IRAK4 MEFV TNF
3
Show member pathways
12.77 IL1B IL6 IRAK4 TNF TNFRSF1A
4
Show member pathways
12.69 IL1B IL6 IRAK4 TNF TNFRSF1A
5
Show member pathways
12.57 IL1B TNF TNFRSF1A TRAF3IP2
6
Show member pathways
12.57 IL1B IL6 IRAK4 TNF TNFRSF1A
7 12.45 IL1B IRAK4 TNF TNFRSF1A
8
Show member pathways
12.24 IL1B IL6 TNF TRAF3IP2
9
Show member pathways
12.15 IL1B IRAK4 TNF TNFRSF1A
10
Show member pathways
12.13 IL1B IL6 IRAK4 TNF
11
Show member pathways
12.07 IL1B IL6 TNF
12
Show member pathways
12.04 IL1B IL6 IRAK4 TNF
13 12.01 IL1B TNF TNFRSF1A
14 11.97 IL1B TNF TNFRSF1A
15 11.93 IL1B IL6 TNF
16 11.9 IL1B IL6 TNF
17
Show member pathways
11.88 IL6 TNF TNFRSF1A
18
Show member pathways
11.87 IL1B IL6 TNF
19 11.83 IL1B IL6 TNF
20 11.81 IL1B IL6 TNF
21 11.8 IL1B IL6 TNF
22 11.76 IL1B IL6 TNF
23 11.74 IL1B IL6 TNF TNFRSF1A
24 11.68 IL1B IL6 TNF
25 11.66 IRAK4 TNF TNFRSF1A
26 11.65 IL1B IRAK4 TNF TNFRSF1A
27 11.61 IL1B IL6 IRAK4 TNF TNFRSF1A
28 11.59 IL1B IL6 TNF
29 11.51 IL1B IL6 TNF
30 11.47 IL6 TNF TNFRSF1A
31 11.44 IL1B IL6 IRAK4 TNF
32 11.43 IL1B IL6 TNF
33 11.38 IL1B IL6 TNF
34
Show member pathways
11.26 IL1B IL6 TNF TNFRSF1A
35 11.23 IL1B IL6 TNF
36 11.21 IL1B IL6 TNF
37 11.16 IL1B IL6 TNF
38 11.12 IL1B IL6 TNF
39 11.09 IL1B IL6 TNF
40 11.06 TNF TNFRSF1A
41 11.04 IL1B TNF
42 11.04 IL6 TNF
43 10.88 IL1B TNF
44 10.83 IL1B IL6
45 10.78 CRP IL6 TNF
46 10.61 IL1B IL6 TNF TNFRSF1A

GO Terms for Pericarditis

Cellular components related to Pericarditis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.23 ADA CRP IL1B IL6 IRAK4 NPPB

Biological processes related to Pericarditis according to GeneCards Suite gene sharing:

(show all 33)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.95 CRP IL1B IL6 TNF
2 immune response GO:0006955 9.95 IL1B IL6 PRG4 TNF TNFRSF1A
3 positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 9.81 IL1B IL6 TNF
4 defense response to Gram-positive bacterium GO:0050830 9.79 CRP IL6 TNF
5 negative regulation of inflammatory response GO:0050728 9.79 ADA MEFV TNFRSF1A
6 positive regulation of smooth muscle cell proliferation GO:0048661 9.71 IL6 IRAK4 TNF
7 humoral immune response GO:0006959 9.7 IL6 TNF TRAF3IP2
8 response to lipopolysaccharide GO:0032496 9.67 IL1B IL6 TNFRSF1A
9 cytokine-mediated signaling pathway GO:0019221 9.67 IL1B IL6 IRAK4 TNFRSF1A
10 positive regulation of NF-kappaB import into nucleus GO:0042346 9.66 IL1B TNF
11 embryonic digestive tract development GO:0048566 9.65 ADA TNF
12 negative regulation of lipid catabolic process GO:0050995 9.65 IL1B TNF
13 positive regulation of interleukin-6 production GO:0032755 9.65 IL1B IL6 TNF
14 positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 9.65 IL1B IRAK4 TNF TNFRSF1A TRAF3IP2
15 positive regulation of chemokine production GO:0032722 9.64 IL6 TNF
16 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.64 IL1B TNF
17 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.63 IL1B TNF
18 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.62 IL1B TNF
19 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.62 IL1B IL6 IRAK4 TNF
20 neutrophil mediated immunity GO:0002446 9.61 IL6 IRAK4
21 positive regulation of nitric oxide biosynthetic process GO:0045429 9.61 IL1B IL6 TNF
22 positive regulation of chemokine biosynthetic process GO:0045080 9.6 IL1B TNF
23 positive regulation of ceramide biosynthetic process GO:2000304 9.59 TNF TNFRSF1A
24 cellular response to mechanical stimulus GO:0071260 9.58 IL1B TNFRSF1A
25 death-inducing signaling complex assembly GO:0071550 9.58 TNF TNFRSF1A
26 response to calcium ion GO:0051592 9.57 IL6 TNNT2
27 epithelial cell proliferation involved in salivary gland morphogenesis GO:0060664 9.56 IL6 TNF
28 positive regulation of fever generation GO:0031622 9.51 IL1B TNF
29 sequestering of triglyceride GO:0030730 9.46 IL1B TNF
30 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.4 IL1B TNF
31 negative regulation of lipid storage GO:0010888 9.33 CRP IL6 TNF
32 inflammatory response GO:0006954 9.17 CRP HRH4 IL1B IL6 MEFV TNF
33 regulation of establishment of endothelial barrier GO:1903140 9.13 IL1B TNF TNFRSF1A

Molecular functions related to Pericarditis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 interleukin-1 receptor binding GO:0005149 8.62 IL1B IRAK4

Sources for Pericarditis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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