MCID: PRN019
MIFTS: 44

Perinatal Necrotizing Enterocolitis malady

Categories: Rare diseases, Fetal diseases, Gastrointestinal diseases, Neuronal diseases, Cancer diseases

Aliases & Classifications for Perinatal Necrotizing Enterocolitis

About this section
Sources:
11Disease Ontology, 13DISEASES, 29ICD10, 30ICD10 via Orphanet, 38MeSH, 44NCIt, 47NIH Rare Diseases, 49Novoseek, 53Orphanet, 61SNOMED-CT, 67UMLS
See all MalaCards sources

Aliases & Descriptions for Perinatal Necrotizing Enterocolitis:

Name: Perinatal Necrotizing Enterocolitis 11 13
Necrotizing Enterocolitis 11 47 53 13 67
Enterocolitis, Necrotizing 47 38
Enterocolitis Necrotizing 11 49
Necrotizing Enterocolitis in Fetus or Newborn 11
 
Pseudomembranous Enterocolitis in Newborn 11
Perinatal Necrotising Enterocolitis 11
Carcinoma, Neuroendocrine 67
Nec 47

Characteristics:

Orphanet epidemiological data:

53
necrotizing enterocolitis:
Prevalence: 1-5/10000 (Worldwide); Age of onset: Neonatal; Age of death: infantile

Classifications:



External Ids:

Disease Ontology11 DOID:8677
MeSH38 D020345
NCIt44 C84915
Orphanet53 ORPHA391673
ICD10 via Orphanet30 P77
ICD1029 P77

Summaries for Perinatal Necrotizing Enterocolitis

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MalaCards based summary: Perinatal Necrotizing Enterocolitis, also known as necrotizing enterocolitis, is related to short bowel syndrome and neurogenic bladder. An important gene associated with Perinatal Necrotizing Enterocolitis is FABP2 (Fatty Acid Binding Protein 2), and among its related pathways are IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types and MIF Action Through Endocytic Pathway. Affiliated tissues include heart, neutrophil and colon, and related mouse phenotype immune system.

Related Diseases for Perinatal Necrotizing Enterocolitis

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Diseases related to Perinatal Necrotizing Enterocolitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 290)
idRelated DiseaseScoreTop Affiliating Genes
1short bowel syndrome30.0CRP, IL6, TNF
2neurogenic bladder10.4TLR4, TNF
3toxic myocarditis10.4IL6, SERPINH1
4aortic arch interruption10.4IL6, TNF
5uterine corpus epithelioid leiomyoma10.4EGF, HBEGF, IL6
6intestinal perforation10.4
7cutaneous leishmaniasis10.4IL6, TNF
8thyroid malformation10.4IL1B, TNF
9basidiobolomycosis10.4CXCL8, TNF
10atrial septal defect coronary sinus10.4IL1B, TLR4
11hypospadias, hypertelorism, upper lid coloboma, and mixed-type hearing loss10.4IL1B, TNF
12aneurysm of sinus of valsalva10.3CRP, IL6
13hemometra10.3IL6, TNF
14tricho odonto onycho dermal syndrome10.3IL6, TNF
15baetz-greenwalt syndrome10.3IL1B, TNF
16pulmonary hypertension10.3IL1B, TNF
17anterior dislocation of lens10.3CXCL8, IL6
18abducens nerve neoplasm10.3CXCL8, IL6, TLR4
19carbon baby syndrome10.3CRP, IL6
20retinal vascular disease10.3CXCL8, IL6
21atrophic vulva10.3CRP, IL6
22antigen-peptide-transporter 2 deficiency10.3IL6, TLR4, TNF
23osteogenesis imperfecta, type x10.3CXCL8, IL6, SERPINH1
24thymus lymphoma10.3EGF, IL6, TNF
25benign adult familial myoclonic epilepsy10.3CXCL8, IL6
26urticaria10.2CXCL8, EGF, IL6
27protozoal dysentery10.2CRP, CXCL8
28gastric ulcer10.2IL6, TLR4, TNF
29maligant granulosa cell tumor of ovary10.2CXCL8, IL6, TNF
30angioma hereditary neurocutaneous10.2CRP, IL6
31brain glioblastoma multiforme10.2CRP, HBEGF, IL6
32pasteurellosis10.2CXCL8, IL6, TNF
33hemoglobinopathy10.2IL1B, IL6
34staphyloenterotoxemia10.2CXCL8, IL6, TNF
35warm antibody hemolytic anemia10.2IL1B, TNF
36dementia - subcortical10.2CXCL8, IL6, TNF
37corneal deposit10.2CXCL8, IL1B, IL6
38tarsal tunnel syndrome10.2CXCL8, IL1B, IL6
39cardiocranial syndrome10.2CRP, CXCL8
40kohler's disease10.2CRP, IL6, THPO
41bartonellosis10.2IL1B, TLR4, TNF
42alcohol abuse10.2CXCL8, IL6, TNF
43burn scar10.2CXCL8, IL6, TNF
44nasopharyngitis10.2IL1B, TLR4, TNF
45dentinogenesis imperfecta10.2CXCL8, IL6, TNF
46conjunctival disease10.2CRP, IL6, TLR4
47gastric hemangioma10.2CRP, CXCL8, TLR4
48focal epilepsy10.2CRP, IL6, THPO
49melioidosis10.2IL6, LY96, TLR4
50gallbladder lymphoma10.2CRP, CXCL8, TLR4

Graphical network of the top 20 diseases related to Perinatal Necrotizing Enterocolitis:



Diseases related to perinatal necrotizing enterocolitis

Symptoms for Perinatal Necrotizing Enterocolitis

About this section

Drugs & Therapeutics for Perinatal Necrotizing Enterocolitis

About this section

Drugs for Perinatal Necrotizing Enterocolitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 225)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Poractant alfaapprovedPhase 425129069-19-8
2
Miconazoleapproved, investigational, vet_approvedPhase 4, Phase 3362422916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
3
Nystatinapproved, vet_approvedPhase 4411400-61-911953884
Synonyms:
(1S,15S,16R,17R,18S,19E,21E,25E,27E,29E,31E)-33-[(3-amino-3,6-dideoxy-a-D-mannopyranosyl)oxy]-1,3,4,7,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,25,27,29,31-hexaene-36-carboxylic acid
(1S,15S,16R,17R,18S,19E,21E,25E,27E,29E,31E)-33-[(3-amino-3,6-dideoxy-alpha-D-mannopyranosyl)oxy]-1,3,4,7,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,25,27,29,31-hexaene-36-carboxylic acid
(4E,6E,8E,10E,14E,16E)-3-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-19,25,27,29,32,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,14,16-hexaene-38-carboxylic acid
(4E,6E,8E,10E,14E,16E,18S,19R,20R,21S,35S)-3-[(2S,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-19,25,27,29,32,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,14,16-hexaene-38-carboxylic acid
(4E,6E,8E,10E,14E,16E,18S,19R,21S,35S)-3-[(3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-19,25,27,29,32,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,14,16-hexaene-38-carboxylic acid
AC1NSKG2
AC1NWAPF
AC1O5FWI
AI3-26526
BCBcMAP01_000244
BSPBio_002119
Barstatin 100
Biofanal
C47H75NO17
CHEBI:473992
CHEMBL1200650
CHEMBL229383
CID5311331
CID5702099
CID6433272
Candex Lotion
Candio-hermal
Caswell No. 607B
Comycin
Diastatin
EINECS 215-749-0
EPA Pesticide Chemical Code 202800
Fungicidin
HMS1920D08
HMS2091L08
HMS500N05
HSDB 3138
Herniocid
IDI1_000263
Korostatin
LS-187914
LS-97612
MolPort-003-665-538
MolPort-003-938-857
MolPort-003-983-447
Moronal
Moronal (antibiotic)
Myconystatin
Mycostatin
Mycostatin 20
 
Mycostatin Pastilles
Mykinac
Mykostatyna
N1638_SIGMA
N3503_SIGMA
N4014_SIGMA
N6261_SIGMA
NSC 150817
NYS
Nilstat
Nistatin
Nistatina
Nistatina [INN-Spanish]
Nyamyc
Nyotran
Nystaform
Nystan
Nystatin
Nystatin A
Nystatin A1
Nystatin A1, A2, A3 complex
Nystatin A2
Nystatin A3
Nystatin G
Nystatin LF (liposome)
Nystatin [INN:BAN:JAN]
Nystatin preparation
Nystatine
Nystatine [INN-French]
Nystatinum
Nystatinum [INN-Latin]
Nystatyna
Nystatyna [Polish]
Nystavescent
Nystex
Nystop
O-V Statin
SMP1_000219
SPECTRUM1500446
Spectrum5_001333
Stamicin
Stamycin
Terrastatin
UNII-BDF1O1C72E
UNII-ZGT9EY838C
Zydin E
nystatin
4
Progesteroneapproved, vet_approvedPhase 4, Phase 2, Phase 3, Phase 153757-83-05994
Synonyms:
(S)-4-Pregnene-3,20-dione
(S)-Pregn-4-en-3,20-dione
(S)-Progesterone
.beta.-Progesterone
.delta.(sup4)-Pregnene-3,20-dione
.delta.4-Pregnene-3,20-dione
17.alpha.-Progesterone
17a-Progesterone
17alpha-Progesterone
17alpha-progesterone
17α-progesterone
1dbb
1h60
257630-50-5
3,20-Pregnene-4
32104FB6-BF81-4F6E-83C2-024DEEAEB272
4-Pregnen-3,20-dione
4-Pregnene-3,20-dione
46665_FLUKA
46665_RIEDEL
57-83-0
753497-20-0
8012-32-6
8023-13-0
AC-700
AC1L1LKF
AI3-51682
Agolutin
Akrolutin
BB_NC-0185
BHR-100
BIDD:ER0547
BIDD:PXR0094
BPBio1_000676
BRD-K64994968-001-03-6
BSPBio_000614
Bio-luton
C00410
CCRIS 533
CHEBI:17026
CHEMBL103
CID5994
CIDR
CMC_13406
COL-1620
CPD000058345
Colprosterone
Corlutin
Corlutina
Corluvite
Corporin
Corpus Luteum Hormone
Corpus luteum hormone
Crinone
Crinone (TN)
Crinone progesterone gel
Curretab
Cyclogest
Cyclogesterin
D00066
D4-Pregnene-3,20-dione
DB00396
DR-2011
Delalutin
Delta(4)-pregnene-3,20-dione
Duraprogen
EINECS 200-350-6
ETI-411
EU-0100895
Endometrin
Estima
FE-999913
Flavolutan
Fologenon
Gelbkoerperhormon
Gesterol
Gesterol 100
Gesterol 50
Gestiron
Gestone
Gestormone
Gestron
Glanducorpin
Gynlutin
Gynoluton
Gynolutone
HMS1569O16
HMS2051O05
HMS2090J07
HSDB 3389
Hormoflaveine
Hormoluton
Hydroxyprogesterone Caproate
Hydroxyprogesterone Caproic acid
LMST02030159
LS-234
Lingusorbs
Lipo-Lutin
Lipolutin
Lopac0_000895
Lucorteum
Lucorteum Sol
Lucorteum sol
Lugesteron
Luteal hormone
Luteinique
Luteocrin normale
Luteodyn
Luteogan
Luteohormone
Luteol
Luteol (VAN)
Luteopur
Luteosan
Luteostab
Luteovis
Luteum
Lutex
Lutidon
Lutin
Lutinus
Lutociclina
Lutocuclin M
Lutocyclin
Lutocyclin M
 
Lutocyclin m
Lutocylin
Lutocylol
Lutoform
Lutogyl
Lutogynon
Lutren
Lutromone
MLS000028517
MLS000758277
MLS001074187
MLS002222367
MPA
Membrettes
Methylpregnone
Micronized Progesterone
MolPort-001-794-643
NCGC00022185-03
NCGC00022185-04
NCGC00022185-05
NCGC00022185-06
NCGC00022185-07
NCGC00022185-08
NCGC00022185-09
NCGC00090798-01
NCGC00090798-02
NCI60_042166
NSC 64377
NSC 9704
NSC-9704
NSC64377
NSC9704
Nalutron
Natural Progesterone
P 0130
P0130_SIGMA
P0478
P3972_SIGMA
P6149_SIGMA
P7556_ALDRICH
P7556_SIGMA
P8783_SIGMA
P9776_SIGMA
PROGESTERONE
Percutacrine
Percutacrine Luteinique
Piaponon
Pranone
Pregn-4-en-3,20-dione
Pregn-4-ene-3,20-dione
Pregnene-3,20-dione
Pregnenedione
Prestwick0_000477
Prestwick1_000477
Prestwick2_000477
Prestwick3_000477
Prestwick_411
Primolut
Prochieve
Progeffik
Progekan
Progestan
Progestasert
Progesterol
Progesteron
Progesterona
Progesterona [INN-Spanish]
Progesterone
Progesterone (JP15/USP/INN)
Progesterone [INN:BAN:JAN]
Progesterone [Progestins]
Progesterone, water-soluble
Progesterone-Water Soluble
Progesterone: HBC complex
Progesteronum
Progesteronum [INN-Latin]
Progestin
Progestogel
Progestol
Progeston
Progestone
Progestosol
Progestrel
Progestron
Progestronol
Progestérone
Projestaject
Prolets
Prolidon
Prolutin
Proluton
Prolutone
Prometrium
Prometrium (TN)
Prontogest
Protormone
S00293
S1705_Selleck
SAM001247039
SMR000058345
SMR000653542
SPBio_002553
SR-01000000088
SR-01000000088-5
Spectrum5_002053
Syngesterone
Syngestrets
Synovex S
Syntolutan
U 3672
UNII-4G7DS2Q64Y
Utrogest
Utrogestan
Vitarrine
WLN: L E5 B666 OV MUTJ A1 E1 FV1
ZINC04428529
beta-Progesterone
bmse000482
component of Cyclogesterin
corpus luteum hormone
delta(4)-Pregnene-3,20-dione
delta(Sup 4)-Pregnene-3,20-dione
delta(Sup4)-pregnene-3,20-dione
delta(sup 4)-Pregnene-3,20-dione
delta4-Pregnene-3,20-dione
luteohormone
nchembio.2007.53-comp14
5
IbuprofenapprovedPhase 4, Phase 3, Phase 250115687-27-13672
Synonyms:
(+-)-2-(P-Isobutylphenyl)propionic acid
(+-)-Ibuprofen
(+-)-P-Isobutylhydratropic acid
(+-)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid
(4-Isobutylphenyl)-alpha-methylacetic acid
(RS)-ibuprofen
139466-08-3
15687-27-1
2-(4-Isobutylphenyl)propanoic acid
4-Isobutylhydratropic acid
58560-75-1
AC-11312
AC1L1GGE
AC1Q1P84
AC1Q1P85
ACHES-N-PAIN
ARONIS23835
Act-3
Actiprofen
Adex 200
Adran
Advil
Advil (TN)
Advil Liqui-Gels
Ak+C2278tren
Alaxan
Algofen
Am-Fam 400
Amelior
Amersol
Amibufen
Anafen
Anco
Andran
Anflagen
Antagil
Antalfene
Antarene
Antiflam
Apo-Ibuprofen
Apsifen
Apsifen-F
Artofen
Artril
Artril 300
BB_SC-1358
BIDD:GT0050
BRN 2049713
Balkaprofen
Betaprofen
Bloom
Bluton
Brofen
Brufanic
Brufen
Brufen 400
Bruflam
Brufort
Buburone
Bufeno
Bufigen
Bukrefen
Bupron
Buracaps
Burana
Butylenin
C01588
C13H18O2
CCRIS 3223
CHEBI:5855
CHEMBL521
CID3672
CPD000058184
Cap-Profen
Carol
Cesra
Children's Advil
Children's Elixsure
Children's Ibuprofen
Children's Motrin
Citalgan
Cobo
Codral
Combiflam
Cunil
D00126
D007052
DB01050
DOLO PUREN
Daiprophen
Dalsy
Dansida
Deep Relief
Dentigoa
Dibufen
Dignoflex
Dolgin
Dolgirid
Dolgit
Dolibu
Dolmaral
Dolo-Dolgit
Dolo-dolgit
Dolocyl
Dolofen
Dolofen-F
Dolofin
Dolofort
Dologel
Dolomax
Doloren
Dolormin
Doltibil
Dolven
Donjust B
Dorival
Drin
Duafen
Duobrus
Dura-Ibu
Duralbuprofen
Dysdolen
EU-0100691
Easifon
Ebufac
Emflam
Emflam-200
Emodin
Epobron
Eputex
Ergix
Esprenit
Exneural
Faspic
Femadon
Femafen
Femapirin
Femidol
Fenbid
Fenbid Spansule
Fendol
Fenspan
Fibraflex
Gelufene
Gofen
Grefen
Gynofug
HMS1920F15
HMS2089P05
HMS2091N03
HMS502M09
HSDB 3099
Haltran
I 4883
I01-7039
I0415
I4883_SIGMA
I7905_SIAL
IB-100
IDI1_000887
IP 82
IP-82
IP82
Ibol
Ibren
Ibu
Ibu-Attritin
Ibu-Slo
Ibu-Tab
Ibu-Tab 200
Ibu-attritin
Ibu-slo
Ibu-slow
Ibubest
Ibubeta
Ibucasen
Ibudol
 
Ibudolor
Ibufen
Ibuflamar
Ibufug
Ibugel
Ibugen
Ibugesic
Ibuhexal
Ibulagic
Ibular
Ibulav
Ibuleve
Ibulgan
Ibumed
Ibumerck
Ibumetin
Ibupirac
Ibuprin
Ibuprocin
Ibuprofen
Ibuprofene
Ibuprofeno
Ibuprofenum
Ibuprohm
Ibuprophen
Ibusal
Ibutid
Ifen
Inabrin
Inflam
Inoven
Ipren
Irfen
Isodol
Jenaprofen
Junifen
Junior Strength Advil
Junior Strength Ibuprofen
Junior Strength Motrin
KBio1_000887
KBio2_001329
KBio2_003897
KBio2_006465
KBio3_001390
Kesan
Kratalgin
LS-7454
Lamidon
Lebrufen
Librofem
Lidifen
Liptan
Lopane
MLS000069733
MLS001146965
Malafene
Manypren
Medipren
Melfen
Mensoton
Midol
Midol 200
Moment
Motrin
Motrin (TN)
Motrin IB
Mynosedin
NCI60_002065
NINDS_000887
NSC 256857
NSC256857
Nagifen-D
Napacetin
Narfen
Neo-Helvagit
Neo-Mindol
NeoProfen
Neobrufen
Nerofen
Noalgil
Nobafon
Nobfelon
Nobfen
Nobgen
Noritis
Norton
Novadol
Novo-Profen
Novogent
Novogent N
Novoprofen
Nuprilan
Nuprin
Nurofen
Optifen
Opturem
Oralfene
Ostarin
Ostofen
Ozonol
P-Isobutylhydratropic Acid
Paduden
Panafen
Pantrop
Para-Isobutylhydratropic Acid
Paxofen
Pedia-Profen
PediaProfen
Pediaprofen
Pediatric Advil
Perofen
Proartinal
Profen
Proflex
Provon
Quadrax
R.D. 13621
RD 13621
Rafen
Ranofen
Rebugen
Relcofen
Rhinadvil
Rofen
Roidenin
Rufen
Rufin
Rupan
SAM002264619
SMR000058184
SPBio_000178
STK177358
Sadefen
Salivia
Salprofen
Seclodin
Sednafen
Seklodin
Seskafen
Siyafen
Solpaflex
Solufen
Stelar
Sugafen
Suprafen
Suspren
Syntofene
TL8001184
Tab-Profen
Tabalon
Tabalon 400
Tatanal
Tempil
Tofen
Togal N
Tonal
Trendar
U 18573
U-18,573
U-18573
UCB 79171
Unipron
Upfen
Uprofen
Urem
VUFB 9649
Zafen
Zofen
alpha-(4-Isobutylphenyl)propionate
alpha-(4-Isobutylphenyl)propionic acid
alpha-(P-Isobutylphenyl)propionic acid
alpha-p-Isobutylphenylpropionate
alpha-p-Isobutylphenylpropionic acid
ibuprofen
p-Isobutyl-2-phenylpropionate
p-Isobutyl-2-phenylpropionic acid
p-Isobutylhydratropate
p-Isobutylhydratropic acid
6
Indomethacinapproved, investigationalPhase 4, Phase 3, Phase 211453-86-13715
Synonyms:
1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid
1z9h
37242-43-6
503560-73-4
53-86-1
74252-25-8 (hydrochloride salt, tri-hydrate)
7681-54-1 (hydrochloride salt)
91853-74-6
AB00052022
AC-532
AC1L1GJQ
AKOS000592893
Aconip
Aconip (TN)
Amuno
Apo-Indomethacin
Arthrexin
Artracin
Artrinovo
Artrivia
BIDD:GT0132
BIM-0050670.0001
BPBio1_000160
BRD-K57222227-001-06-1
BRN 0497341
BSPBio_000144
BSPBio_001149
BSPBio_002176
Bio-0704
Bio2_000405
Bio2_000885
Bonidin
Bonidon
Bonidon Gel
C01926
CAS-53-86-1
CCRIS 3502
CHEBI:49662
CHEMBL6
CID3715
CPD-10545
Catlep
Chibro-amuno
Chrono-indicid
Chrono-indocid
Confortid
D00141
DB00328
DESMETHYL INDOMETHACIN
DivK1c_000271
Dolcidium
Dolcidium PL
Dolovin
Durametacin
EINECS 200-186-5
EU-0100692
Elmetacin
Flexin continus
HMS1362I11
HMS1568H06
HMS1792I11
HMS1920F21
HMS1990I11
HMS2089N19
HMS2091N09
HMS500N13
HSDB 3101
Hicin
I 7378
I0655
I7378_SIGMA
I8280_SIGMA
IDI1_000271
IDI1_002160
IMN
IN1454
Idomethine
Imbrilon
Inacid
Indacin
Indameth
Indmethacine
Indo-Lemmon
Indo-Spray
Indo-phlogont
Indo-rectolmin
Indo-tablinen
Indocid
Indocid (pharmaceutical)
Indocid Pda
Indocid Sr
Indocin
Indocin (TN)
Indocin I.V
Indocin I.V.
Indocin Sr
Indolar SR
Indomecol
Indomed
Indomee
Indomet 140
Indometacin
Indometacin (JP15/INN)
Indometacina
Indometacina [INN-Spanish]
Indometacine
Indometacine [INN-French]
Indometacinum
 
Indometacinum [INN-Latin]
Indometacyna
Indometacyna [Polish]
Indomethacin
Indomethacin & MAP-30
Indomethacin (USP)
Indomethacin [USAN:BAN]
Indomethacin, Indochron E-R, Indocin-SR, Indocid, Indocin, Indomethacin
Indomethacine
Indomethacinum
Indomethancin
Indomethazine
Indomethegan
Indomethine
Indometicina
Indometicina [Spanish]
Indomo
Indomod
Indoptic
Indoptol
Indorektal
Indoxen
Inflazon
Infrocin
Inteban sp
KBio1_000271
KBio2_000489
KBio2_001399
KBio2_003057
KBio2_003967
KBio2_005625
KBio2_006535
KBio3_000897
KBio3_000898
KBio3_001396
KBioGR_000395
KBioGR_000489
KBioSS_000489
KBioSS_001399
L000959
LS-187
LS-82147
Lausit
Liometacen
Lopac-I-7378
Lopac0_000692
MLS000069402
MLS000758212
MLS001074194
Metacen
Metartril
Methazine
Metindol
Mezolin
Miametan
Mikametan
Mobilan
MolMap_000032
MolPort-000-917-894
NCGC00015562-01
NCGC00015562-02
NCGC00015562-03
NCGC00015562-08
NCGC00015562-19
NCGC00024135-02
NCGC00024135-04
NCGC00024135-05
NCGC00024135-06
NCGC00024135-07
NCGC00024135-08
NCGC00024135-09
NCGC00024135-11
NCI-C56144
NCI60_041708
NINDS_000271
Novo-Methacin
Novomethacin
Oprea1_686105
Prestwick0_000272
Prestwick1_000272
Prestwick2_000272
Prestwick3_000272
Prestwick_597
Reumacide
Rhemacin LA
Rheumacin LA
S00108
S1723_Selleck
SMR000058195
SMR000449290
SPBio_000979
SPBio_002363
SPECTRUM1500350
Sadoreum
Spectrum2_000970
Spectrum3_000468
Spectrum4_000018
Spectrum5_000868
Spectrum_000919
Tannex
Tocris-1708
UNII-XXE1CET956
UPCMLD-DP023
UPCMLD-DP023:001
USAN
Vonum
indometacin
indomethacin
nchembio.147-comp11
{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid
7
Caffeineapproved, NutraceuticalPhase 4, Phase 338058-08-22519
Synonyms:
07E4FB58-FD79-4175-8E3D-05BF96954522
1,3,7-Trimethyl-2,6-dioxopurine
1,3,7-Trimethyl-3,7-dihydro-1H-purine-2,6-dione
1,3,7-Trimethylpurine-2,6-dione
1,3,7-Trimethylxanthine
1,3,7-trimethyl-2,6-dioxopurine
1,3,7-trimethylpurine-2,6-dione
1,3,7-trimethylxanthine
1-3-7-TRIMETHYLXANTHINE
1-Methyl-Theobromine
1-methyltheobromine
137X
1gfz
1l5q
1l7x
27602_FLUKA
2a3b
3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion
3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
3,7-dihydro-1,3,7-trimethyl-1H-purine
5-26-13-00558 (Beilstein)
58-08-2
7-Methyl Theophylline
7-Methyltheophylline
7-methyltheophylline
71701-02-5
75035_FLUKA
95789-13-2
A.S.A. and Codeine Compound
AC-12774
AC1L1DV2
AC1Q3Z23
ACon1_000085
AI3-20154
AKOS000121334
Alert-Pep
Alert-pep
Anacin Maximum Strength
Anhydrous caffeine
Anhydrous caffeine (JP15)
Anhydrous caffeine (TN)
Anoquan
BIDD:ER0554
BIDD:GT0632
BIDD:PXR0172
BIM-0050216.0001
BRD-K02404261-001-02-7
BRD-K02404261-001-03-5
BRN 0017705
BSPBio_001921
Berlin-Chemie Brand of Caffeine
Bio-0579
Bio1_000473
Bio1_000962
Bio1_001451
Bristol-Myers Squibb Brand of Caffeine
C 0750
C07481
C0750_SIAL
C1778_SIAL
C2042
C6035_FLUKA
C6035_SIGMA
C7731_SIAL
C8960_SIAL
CCRIS 1314
CFF
CHEBI:27732
CHEMBL113
CID2519
CU-01000012617-3
Cafamil
Cafcit
Cafecon
Cafeina
Cafergot
Cafeína
Caffedrine
Caffedrine Caplets
Caffein
Caffeina
Caffeina [Italian]
Caffeine (USP)
Caffeine (natural)
Caffeine Pure
Caffeine [BAN:JAN]
Caffeine solution
Caffeine, Anhydrous
Caffeine, Monohydrate
Caffeine, Synthetic
Caffeine, anhydrous
Caffeine, synthetic
Caffeinum
Caffine
Cafipel
Caféine
Coffein
Coffein [German]
Coffeine
Coffeinum
Coffeinum N
Coffeinum Purrum
Compound 65
D002110
D00528
DB00201
DHC Plus
DHCplus
Darvon Compound
Darvon Compound-65
Dasin
Dexitac
Dexitac Stay Alert Stimulant
Dhc Plus
Diurex
DivK1c_000730
Durvitan
EINECS 200-362-1
EU-0100228
Eldiatric C
Enerjets
Ercatab
Esgic
Esgic-Plus
FEMA No. 2224
Femcet
Fioricet
Fiorinal
GlaxoSmithKline Brand of Caffeine
Guaranine
HMS1920I09
HMS2091O11
HMS502E12
HSDB 36
Hycomine
Hycomine Compound
I14-4386
 
IDI1_000730
Invagesic
Invagesic Forte
KBio1_000730
KBio2_001781
KBio2_004349
KBio2_006917
KBio3_001141
KBioGR_002325
KBioSS_001781
Keep Alert
Kofein
Kofein [Czech]
Koffein
Koffein [German]
L000155
LS-237
Lanorinal
Lopac-C-0750
Lopac0_000228
MEGxp0_001350
MLS001055341
MLS001056714
MLS001066409
Mateina
Mateína
Maximum Strength Snapback Stimulant Powders
Medigesic Plus
Merck dura Brand of Caffeine
Methyltheobromide
Methyltheobromine
Methylxanthine theophylline
Midol Maximum Strength
Migergot
Miudol
MolMap_000054
MolPort-000-730-850
Monohydrate Caffeine
Monomethyl Derivative of Theophylline
Monomethyl derivative of Theophylline
NCGC00015208-01
NCGC00015208-02
NCGC00015208-04
NCGC00015208-14
NCGC00090699-01
NCGC00090699-02
NCGC00090699-03
NCGC00090699-04
NCGC00090699-05
NCGC00090699-06
NCGC00090699-07
NCGC00090699-08
NCGC00090699-09
NCGC00168808-01
NCGC00168808-02
NCI-C02733
NCIOpen2_008255
NINDS_000730
NSC 5036
NSC5036
Natural Caffeinum
Nix Nap
No Doz
No-Doz
Nodaca
Nodoz Maximum Strength Caplets
Norgesic
Norgesic Forte
Organex
Orphengesic
Orphengesic Forte
P-A-C Analgesic Tablets
PDSP1_001016
PDSP1_001235
PDSP2_001000
PDSP2_001219
Passauer Brand of Caffeine
Pep-Back
Percoffedrinol N
Percutafeine
Phensal
Pierre Fabre Brand of Caffeine
Probes1_000150
Probes2_000128
Propoxyphene
Propoxyphene Compound 65
Propoxyphene Compound-65
Quick Pep
Quick-Pep
Refresh'n
Republic Drug Brand of Caffeine
SDCCGMLS-0064595.P001
SDCCGMLS-0064595.P002
SK 65 Compound
SK-65 Compound
SMR000326667
SPBio_001222
SPECTRUM1500155
STK177283
Seid Brand of Caffeine
Spectrum2_001261
Spectrum3_000321
Spectrum4_001782
Spectrum5_000423
Spectrum_001301
Stim
Synalgos-Dc
TNP00310
Thein
Theine
Theobromine ME
Theobromine Me
Theophylline ME
Theophylline Me
Theophylline, 7-methyl
Thompson Brand 1 of Caffeine
Thompson Brand 2 of Caffeine
Tirend
Tri-Aqua
Triad
UNII-3G6A5W338E
Ultra Pep-Back
Vivarin
W222402_ALDRICH
WLN: T56 BN DN FNVNVJ B1 F1 H1
Wake-Up
Wigraine
Xanthine, 1,3,7-trimethyl
ZINC00001084
bmse000206
cafeine
caffeine
caffenium
component of Cafergot
nchembio.243-comp7
nchembio.63-comp5
nchembio774-comp2
teina
teína
8HormonesPhase 4, Phase 2, Phase 3, Phase 113979
9Hormone AntagonistsPhase 4, Phase 2, Phase 3, Phase 112778
10Peripheral Nervous System AgentsPhase 4, Phase 3, Phase 2, Phase 122776
11Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 2, Phase 3, Phase 112767
12Phosphodiesterase InhibitorsPhase 4, Phase 3, Phase 21254
13AnalgesicsPhase 4, Phase 3, Phase 211287
14Calcium, DietaryPhase 4, Phase 3, Phase 25525
15Respiratory System AgentsPhase 4, Phase 3, Phase 2, Phase 14818
16Pulmonary SurfactantsPhase 4, Phase 3, Phase 2107
17Tocolytic AgentsPhase 4, Phase 3, Phase 2708
18Anti-Inflammatory AgentsPhase 4, Phase 3, Phase 2, Phase 110355
19ProgestinsPhase 4, Phase 2, Phase 3, Phase 1546
20Estrogen AntagonistsPhase 4, Phase 2, Phase 3, Phase 11315
21EstrogensPhase 4, Phase 2, Phase 3, Phase 12470
22
IodinePhase 45467553-56-2807
Synonyms:
I2
Iode
Iodine-molecule
 
Iodio
Iodum
Jod
Jood
Tincture iodine
23Antibiotics, AntitubercularPhase 4, Phase 3, Phase 1, Phase 26972
24Antitubercular AgentsPhase 4, Phase 3, Phase 21272
25Trace ElementsPhase 4, Phase 3, Phase 25802
26MicronutrientsPhase 4, Phase 3, Phase 25802
27cadexomer iodinePhase 4514
2817-alpha-hydroxy-progesterone caproatePhase 4, Phase 2, Phase 3, Phase 131
29Anti-Infective Agents, LocalPhase 41785
30Neurotransmitter AgentsPhase 4, Phase 3, Phase 2, Phase 117734
31Analgesics, Non-NarcoticPhase 4, Phase 3, Phase 26260
32Anti-Inflammatory Agents, Non-SteroidalPhase 4, Phase 3, Phase 24295
33Antirheumatic AgentsPhase 4, Phase 3, Phase 210627
34IonophoresPhase 448
35Antifungal AgentsPhase 4, Phase 33615
36Anti-Infective AgentsPhase 4, Phase 3, Phase 1, Phase 221402
37LactoferrinPhase 447
38Anti-Bacterial AgentsPhase 4, Phase 3, Phase 1, Phase 210884
39AnticoagulantsPhase 4, Phase 32516
40Cyclooxygenase InhibitorsPhase 4, Phase 3, Phase 22778
4111-hydroxyprogesteronePhase 4, Phase 2, Phase 3, Phase 131
42Purinergic P1 Receptor AntagonistsPhase 4, Phase 3348
43Chelating AgentsPhase 4, Phase 31365
44Central Nervous System StimulantsPhase 4, Phase 32132
45Caffeine citratePhase 4, Phase 318
46AcidophilusNutraceuticalPhase 4, Phase 3, Phase 2518
47BifidobacteriumNutraceuticalPhase 4, Phase 3, Phase 2230
48
Citric Acidnutraceutical, vet_approvedPhase 4, Phase 3, Phase 2110677-92-9311
Synonyms:
2-Hydroxy-1,2,3-propanetricarboxylate
2-Hydroxy-1,2,3-propanetricarboxylic acid
2-Hydroxytricarballylic acid
3-Carboxy-3-hydroxypentane-1,5-dioate
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Aciletten
Anhydrous citrate
Anhydrous citric acid
Chemfill
Citraclean
 
Citrate
Citretten
Citric acid
Citro
Citronensäure
E 330
Hydrocerol A
Kyselina citronova
Suby G
Uro-trainer
beta-Hydroxytricarballylate
beta-Hydroxytricarballylic acid
49CitrateNutraceuticalPhase 4, Phase 3, Phase 21106
50CaproateNutraceuticalPhase 4, Phase 2, Phase 3, Phase 133

Interventional clinical trials:

(show top 50)    (show all 271)
idNameStatusNCT IDPhase
1Withholding Feeds During Red Blood Cell Transfusion and TRAGIUnknown statusNCT02132819Phase 4
2The Effect of Probiotics on Exacerbation of Inflammatory Bowel Disease Exacerbation (Crohn's Disease)Unknown statusNCT01765998Phase 4
3Cpap at Delivery Room for Preterm InfantsUnknown statusNCT01024361Phase 4
4Intragastric and Peritoneal Microdialysis in Infants With Necrotizing Enterocolitis (NEC)CompletedNCT00332592Phase 4
5Probiotics to Prevent NEC - a Historical Control StudyCompletedNCT01670916Phase 4
6Early Versus Late Lactoferrin in Prevention of Neonatal SepsisCompletedNCT02959229Phase 4
7Comparison of Lactobacillus Reuteri and Nystatin Prophylaxis on Candida Colonization and Infection in Very Low Birth Weight InfantsCompletedNCT01531192Phase 4
8Ibuprofen and Renal Function in Premature InfantsCompletedNCT00217191Phase 4
9MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose CaffeineCompletedNCT00809055Phase 4
10Efficacy of 17 Alpha-hydroxyprogesterones Caproate for the Prevention of Preterm DeliveryCompletedNCT00331695Phase 4
11Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part IVCompletedNCT01604447Phase 4
12Evaluate the Use of Plastic Bags in Preventing and Treating Hypothermia in NeonatesCompletedNCT01403623Phase 4
13A Randomised Controlled Trial of Iodide Supplementation in Preterm Infants Follow-up at 2 YearsCompletedNCT00638092Phase 4
14Impact of Oral Application of Gastrografin on the Meconium Evacuation in Very Low Birth Weight InfantsCompletedNCT01515696Phase 4
15OPTIMIST-A Trial: Minimally-invasive Surfactant Therapy in Preterm Infants 25-28 Weeks Gestation on CPAPRecruitingNCT02140580Phase 4
16Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part IIRecruitingNCT01604421Phase 4
17Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part IRecruitingNCT01604317Phase 4
18Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part IIIRecruitingNCT01604434Phase 4
19Removal Versus Retention of Cerclage in Preterm Premature Rupture of Membranes (PPROM)TerminatedNCT00201656Phase 4
20Sodium Supplementation and Growth in Very Low Birth Weight InfantsTerminatedNCT01795638Phase 4
21RCT of Postoperative Infections Following Caesarean Section Infections Following Caesarean SectionWithdrawnNCT02009098Phase 4
22Comparing Ibuprofen And Indomethacin For The Treatment Of The Patent Ductus Arteriosus in Very Premature BabiesWithdrawnNCT00470743Phase 4
23Effect of Saccharomyces Boulardii on Necrotizing Enterocolitis in Very Low Birth Weight InfantsUnknown statusNCT01315821Phase 3
24Early Provision of Enteral Microlipid and Fish Oil to Infants With EnterostomyUnknown statusNCT01306838Phase 3
25Randomized Study of Pessary Versus Standard Management in Women With Increased Chance of Premature BirthUnknown statusNCT00735137Phase 3
26Cysteine Supplementation in Critically Ill NeonatesUnknown statusNCT00254176Phase 2, Phase 3
27Efficacy Study of Hypothermia Plus Magnesium Sulphate(MgSO4) in the Management of Term and Near Term Babies With Hypoxic Ischemic EncephalopathyUnknown statusNCT01646619Phase 3
28Lactobacillus Reuteri for Prevention of Necrotizing Enterocolitis in Very Low-birth Weight InfantsCompletedNCT01531179Phase 3
29Probiotics in the Management of Necrotizing Enterocolitis in HIV-exposed Premature InfantsCompletedNCT01868737Phase 3
30The Efficacy of Symbiotic on CytokinesCompletedNCT01899677Phase 3
31Role of Probiotics for Prevention of NEC in Preterm VLBW InfantsCompletedNCT02650869Phase 3
32Effect of Oral Probiotic Supplementation on The Rate of Hospital Acquired Infection and Necrotizing Enterocolitis in Preterm Very Low Birth Weight InfantsCompletedNCT01340469Phase 3
33Effect of Vitamin A in the Treatment of Neonatal Sepsis and Necrotizing EnterocolitisCompletedNCT00707785Phase 3
34A Single Blinded Study on the Effect of Saccharomyces Boulardii CNCM I-745 on Growth and Development in Preterm InfantsCompletedNCT02310425Phase 3
35Prevention Trial of Nosocomial Infections in Neutropenic Prematures With G-CSFCompletedNCT00213759Phase 3
36Progesterone Vaginal Pessary for Prevention of Preterm Twin BirthCompletedNCT02350231Phase 2, Phase 3
37Ursodiol for Treating Parenteral Nutrition Associated Cholestasis in NeonatesCompletedNCT00846963Phase 2, Phase 3
38Trial of Indomethacin Prophylaxis in Preterm Infants (TIPP)CompletedNCT00009646Phase 3
39Intravenous Immunoglobulin in Prevention of Preterm Neonatal SepsisCompletedNCT02954926Phase 3
40PREGNANT Short Cervix TrialCompletedNCT00615550Phase 3
41Intravenous Immune Globulin (IVIG) to Prevent Neonatal InfectionCompletedNCT01203345Phase 2, Phase 3
4217OHP for Reduction of Neonatal Morbidity Due to Preterm Birth (PTB) in Twin and Triplet PregnanciesCompletedNCT00163020Phase 2, Phase 3
43Caffeine for Apnea of Prematurity (CAP)CompletedNCT00182312Phase 3
44NIV Strategies for RDS in Preterm Infants. NIV (Non Invasive Ventilation), RDS (Respiratory Distress Syndrome)CompletedNCT02259400Phase 2, Phase 3
45Fluconazole Prophylaxis for the Prevention of Candidiasis in Infants Less Than 750 Grams BirthweightCompletedNCT00734539Phase 3
46Glutamine Supplementation to Prevent Death or Infection in Extremely Premature InfantsCompletedNCT00005775Phase 3
47Canadian Oxygen Trial (COT)CompletedNCT00637169Phase 3
48Nasal Intermittent Positive Pressure Ventilation in Premature Infants (NIPPV)CompletedNCT00433212Phase 3
49Pentoxifylline and Late Onset Sepsis in Preterm InfantsCompletedNCT02163174Phase 3
50High Versus Low Dose of Caffeine for Apnea of PrematurityCompletedNCT02103777Phase 3

Search NIH Clinical Center for Perinatal Necrotizing Enterocolitis


Cochrane evidence based reviews: enterocolitis, necrotizing

Genetic Tests for Perinatal Necrotizing Enterocolitis

About this section

Anatomical Context for Perinatal Necrotizing Enterocolitis

About this section

MalaCards organs/tissues related to Perinatal Necrotizing Enterocolitis:

35
Heart, Neutrophil, Colon, Brain, Cervix, Lung, T cells

Animal Models for Perinatal Necrotizing Enterocolitis or affiliated genes

About this section

MGI Mouse Phenotypes related to Perinatal Necrotizing Enterocolitis:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053876.5CRP, EGF, IL1B, IL6, LY96, PLA2G7

Publications for Perinatal Necrotizing Enterocolitis

About this section

Variations for Perinatal Necrotizing Enterocolitis

About this section

Expression for genes affiliated with Perinatal Necrotizing Enterocolitis

About this section
Search GEO for disease gene expression data for Perinatal Necrotizing Enterocolitis.

Pathways for genes affiliated with Perinatal Necrotizing Enterocolitis

About this section

Pathways related to Perinatal Necrotizing Enterocolitis according to GeneCards Suite gene sharing:

(show all 48)
idSuper pathwaysScoreTop Affiliating Genes
19.7IL1B, IL6
29.7LY96, TLR4
39.6CXCL8, EGF, HBEGF
49.6EGF, IL6, TLR4
59.5CXCL8, HBEGF, IL6
69.4IL6, TLR4, TNF
7
Show member pathways
9.4IL1B, IL6, TLR4
89.4EGF, HBEGF, IL6, THPO
99.3CXCL8, IL6, TNF
109.3IL1B, TLR4, TNF
119.3CXCL8, IL1B, IL6
129.3IL1B, IL6, TNF
139.3IL1B, IL6, TNF
149.3IL1B, IL6, TNF
159.3IL1B, IL6, TNF
169.3LY96, TLR4, TNF
179.2EGF, IL6, TLR4, TNF
18
Show member pathways
9.0CXCL8, IL1B, IL6, TLR4
199.0IL1B, IL6, THPO, TNF
209.0IL1B, IL6, TLR4, TNF
219.0IL1B, IL6, TLR4, TNF
22
Show member pathways
9.0IL1B, IL6, TLR4, TNF
238.9CXCL8, IL1B, IL6, TNF
24
Show member pathways
8.9CXCL8, IL1B, IL6, TNF
25
Show member pathways
8.9CXCL8, IL1B, IL6, TNF
268.9CXCL8, IL1B, IL6, TNF
27
Show member pathways
8.9CXCL8, IL1B, IL6, TNF
288.9CXCL8, IL1B, IL6, TNF
29
Show member pathways
8.8IL1B, LY96, TLR4, TNF
30
Show member pathways
8.8CXCL8, EGF, IL1B, IL6, THPO
318.6CXCL8, IL1B, IL6, TLR4, TNF
328.6CXCL8, IL1B, IL6, TLR4, TNF
338.6CXCL8, IL1B, IL6, TLR4, TNF
348.6CXCL8, IL1B, IL6, TLR4, TNF
358.6CXCL8, IL1B, IL6, TLR4, TNF
36
Show member pathways
8.6CXCL8, IL1B, IL6, TLR4, TNF
37
Show member pathways
8.5EGF, IL1B, IL6, THPO, TLR4, TNF
388.4CXCL8, IL1B, LY96, TLR4, TNF
39
Show member pathways
8.2IL1B, LY96, SIGIRR, TLR4, TNF
40
Show member pathways
8.1CXCL8, EGF, IL1B, IL6, THPO, TLR4
41
Show member pathways
8.1CXCL8, IL1B, IL6, LY96, TLR4, TNF
428.1CXCL8, IL1B, IL6, LY96, TLR4, TNF
43
Show member pathways
8.1CXCL8, IL1B, IL6, LY96, TLR4, TNF
44
Show member pathways
8.1CXCL8, IL1B, IL6, LY96, TLR4, TNF
45
Show member pathways
7.8CXCL8, EGF, HBEGF, IL1B, IL6, PLA2G7
46
Show member pathways
7.6CXCL8, EGF, IL1B, IL6, LY96, THPO
47
Show member pathways
7.5CXCL8, IL1B, IL6, LY96, SIGIRR, TLR4
48
Show member pathways
6.8CRP, EGF, HBEGF, IL1B, IL6, LY96

GO Terms for genes affiliated with Perinatal Necrotizing Enterocolitis

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Cellular components related to Perinatal Necrotizing Enterocolitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1lipopolysaccharide receptor complexGO:004669610.3LY96, TLR4
2extracellular regionGO:00055767.3CRP, CXCL8, EGF, HBEGF, IL1B, IL6
3extracellular spaceGO:00056156.5CRP, CXCL8, EGF, HBEGF, IL1B, IL6

Biological processes related to Perinatal Necrotizing Enterocolitis according to GeneCards Suite gene sharing:

(show all 43)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of interleukin-8 biosynthetic processGO:004541610.4TLR4, TNF
2epithelial cell proliferation involved in salivary gland morphogenesisGO:006066410.4IL6, TNF
3detection of lipopolysaccharideGO:003249710.3LY96, TLR4
4MyD88-independent toll-like receptor signaling pathwayGO:000275610.3LY96, TLR4
5negative regulation of MyD88-independent toll-like receptor signaling pathwayGO:003412810.3LY96, TLR4
6toll-like receptor 4 signaling pathwayGO:003414210.3LY96, TLR4
7positive regulation of calcidiol 1-monooxygenase activityGO:006055910.3IL1B, TNF
8positive regulation of membrane protein ectodomain proteolysisGO:005104410.3IL1B, TNF
9sequestering of triglycerideGO:003073010.3IL1B, TNF
10chronic inflammatory response to antigenic stimulusGO:000243910.3IL1B, TNF
11regulation of establishment of endothelial barrierGO:190314010.3IL1B, TNF
12positive regulation of chemokine biosynthetic processGO:004508010.3IL1B, TNF
13negative regulation of chemokine biosynthetic processGO:004507910.2IL6, SIGIRR
14positive regulation of heterotypic cell-cell adhesionGO:003411610.2IL1B, TNF
15positive regulation of fever generationGO:003162210.2IL1B, TNF
16negative regulation of lipid catabolic processGO:005099510.2IL1B, TNF
17embryonic digestive tract developmentGO:004856610.2CXCL8, TNF
18positive regulation of chemokine productionGO:003272210.1IL6, TLR4, TNF
19regulation of I-kappaB kinase/NF-kappaB signalingGO:004312210.1IL1B, TNF
20positive regulation of smooth muscle cell proliferationGO:004866110.0HBEGF, IL6, TNF
21necroptotic processGO:00702669.9LY96, TLR4
22positive regulation of NF-kappaB import into nucleusGO:00423469.9IL1B, TLR4, TNF
23positive regulation of interferon-gamma productionGO:00327299.9IL1B, TLR4, TNF
24I-kappaB kinase/NF-kappaB signalingGO:00072499.8LY96, TLR4, TNF
25positive regulation of JNK cascadeGO:00463309.8IL1B, TLR4, TNF
26negative regulation of lipid storageGO:00108889.7CRP, IL6, TNF
27positive regulation of protein kinase B signalingGO:00518979.7HBEGF, IL6, THPO, TNF
28positive regulation of sequence-specific DNA binding transcription factor activityGO:00510919.6IL1B, IL6, TNF
29positive regulation of interleukin-8 productionGO:00327579.6IL1B, TLR4, TNF
30acute-phase responseGO:00069539.5CRP, IL6, SIGIRR
31positive regulation of NF-kappaB transcription factor activityGO:00510929.4IL1B, IL6, TLR4, TNF
32lipopolysaccharide-mediated signaling pathwayGO:00316639.4IL1B, LY96, TLR4, TNF
33apoptotic signaling pathwayGO:00971909.4LY96, TLR4, TNF
34positive regulation of interleukin-6 productionGO:00327559.4IL1B, IL6, TLR4, TNF
35MAPK cascadeGO:00001659.3EGF, HBEGF, IL1B, TNF
36positive regulation of nitric oxide biosynthetic processGO:00454299.2IL1B, IL6, TLR4, TNF
37activation of MAPK activityGO:00001879.2EGF, IL1B, TLR4, TNF
38response to lipopolysaccharideGO:00324969.2IL1B, IL6, LY96, TLR4
39cellular response to lipopolysaccharideGO:00712229.0CXCL8, IL6, LY96, TLR4, TNF
40defense response to Gram-positive bacteriumGO:00508308.9CRP, IL6, TNF
41positive regulation of ERK1 and ERK2 cascadeGO:00703748.7IL1B, IL6, THPO, TLR4, TNF
42positive regulation of gene expressionGO:00106288.4CRP, IL1B, IL6, TLR4, TNF
43inflammatory responseGO:00069547.9CRP, CXCL8, IL1B, IL6, LY96, TLR4

Molecular functions related to Perinatal Necrotizing Enterocolitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1lipopolysaccharide receptor activityGO:000187510.2LY96, TLR4
2growth factor activityGO:00080839.4EGF, HBEGF, IL6, THPO
3cytokine activityGO:00051258.7IL1B, IL6, THPO, TNF

Sources for Perinatal Necrotizing Enterocolitis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet