NEC
MCID: PRN019
MIFTS: 42

Perinatal Necrotizing Enterocolitis (NEC) malady

Categories: Rare diseases, Fetal diseases, Gastrointestinal diseases

Aliases & Classifications for Perinatal Necrotizing Enterocolitis

About this section
Sources:
11Disease Ontology, 13DISEASES, 30ICD10, 31ICD10 via Orphanet, 39MeSH, 45NCIt, 48NIH Rare Diseases, 50Novoseek, 54Orphanet, 62SNOMED-CT, 68UMLS
See all MalaCards sources

Aliases & Descriptions for Perinatal Necrotizing Enterocolitis:

Name: Perinatal Necrotizing Enterocolitis 11 13
Necrotizing Enterocolitis 11 48 54 13 68
Enterocolitis, Necrotizing 48 39
Enterocolitis Necrotizing 11 50
 
Necrotizing Enterocolitis in Fetus or Newborn 11
Pseudomembranous Enterocolitis in Newborn 11
Perinatal Necrotising Enterocolitis 11
Nec 48

Characteristics:

Orphanet epidemiological data:

54
necrotizing enterocolitis:
Prevalence: 1-5/10000 (Worldwide); Age of onset: Neonatal; Age of death: infantile

Classifications:



External Ids:

Disease Ontology11 DOID:8677
MeSH39 D020345
NCIt45 C84915
Orphanet54 ORPHA391673
ICD10 via Orphanet31 P77
ICD1030 P77

Summaries for Perinatal Necrotizing Enterocolitis

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NIH Rare Diseases:48 Necrotizing enterocolitis (nec) is a condition characterized by variable injury or damage to the intestinal tract, causing death of intestinal tissue. the condition most often occurs in premature newborns, but it may also occur in term or near-term babies. signs and symptoms may include abdominal distension, bloody stools, vomiting bile-stained fluid, and pneumatosis intestinalis (gas in the bowel wall) identified on abdominal x-ray. affected infants occasionally have temperature instability, lethargy, or other findings of sepsis. the exact cause of nec is unknown. treatment involves stopping feedings, passing a small tube into the stomach to relieve gas, and giving intravenous fluids and antibiotics. surgery may be needed if there is perforated or necrotic (dead) bowel tissue. about 60-80% of affected newborns survive the condition. last updated: 2/4/2013

MalaCards based summary: Perinatal Necrotizing Enterocolitis, also known as necrotizing enterocolitis, is related to intestinal perforation and intussusception. An important gene associated with Perinatal Necrotizing Enterocolitis is FABP2 (Fatty Acid Binding Protein 2), and among its related pathways are IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types and MIF Action Through Endocytic Pathway. Related mouse phenotype immune system.

Wikipedia:71 Necrotizing enterocolitis (NEC) is a medical condition primarily seen in premature infants, where... more...

Related Diseases for Perinatal Necrotizing Enterocolitis

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Diseases related to Perinatal Necrotizing Enterocolitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 249)
idRelated DiseaseScoreTop Affiliating Genes
1intestinal perforation10.4
2intussusception10.2IL1B, TNF
3coloboma of iris10.2CRP, IL6
4vps11-related autosomal recessive hypomyelinating leukodystrophy10.2IL6, TNF
5lateral cystocele10.2CXCL8, IL6, TLR4
6vitreoretinopathy, neovascular inflammatory10.2CXCL8, IL6, SERPINH1
7gastric leiomyoma10.2IL1B, IL6, TLR4
8premature menopause10.1CRP, EGF, IL6
9oculomotor nerve paralysis10.1CXCL8, IL1B, IL6
10common peroneal nerve lesion10.1CXCL8, IL1B, IL6
11brain injury10.1CRP, HBEGF, IL6
12appendiceal l-cell glucagon-like peptide producing tumor10.1CRP, CXCL8, TLR4
13carbuncle10.1CXCL8, IL1B, IL6
14aortic coarctation10.1IL6, TLR4, TNF
15blind hypotensive eye10.1CRP, IL6, THPO
16megaloblastic anemia10.1CRP, IL1B, TLR4
17gait apraxia10.1CRP, IL6, TLR4
18tau syndrome10.1IL1B, TNF
19uterine corpus dissecting leiomyoma10.1CXCL8, EGF, HBEGF, IL6
20fallopian tube serous adenocarcinoma10.1CRP, CXCL8, IL6
21laryngotracheoesophageal cleft type 210.1CRP, IL1B, IL6
22usher syndrome, type 2a10.1IL6, LY96, TLR4
23dyslexia 510.1IL6, TNF
24mixed mineral dust pneumoconiosis10.1CRP, CXCL8, IL6
25breast apocrine carcinoma in situ10.1CXCL8, IL1B, IL6
26thymic neuroendocrine carcinoma10.1CXCL8, IL6, TNF
27allergic bronchopulmonary aspergillosis10.1CRP, CXCL8, IL6
28long bones of lower limb cancer10.1EGF, IL6, TNF
29esophagus lymphoma10.1CXCL8, IL6, TNF
30rickettsialpox10.1IL1B, TLR4, TNF
31mansonelliasis10.1IL6, TLR4, TNF
32trichomalacia10.1CXCL8, IL6, TNF
33hidradenitis10.1CRP, CXCL8, IL1B
34gastric dilatation10.1CXCL8, IL6, TNF
35anal paget's disease10.1IL1B, IL6, TNF
36bipolar i disorder10.1IL1B, IL6, TNF
37orthostatic proteinuria10.1CXCL8, IL6, TNF
38tinea capitis10.1IL1B, IL6, TNF
39erb-duchenne and dejerine-klumpke palsies10.1CXCL8, IL6, TNF
40dextrocardia10.1IL1B, IL6, TNF
41steroid dehydrogenase deficiency dental anomalies10.1IL1B, IL6, TNF
42wilkes stevenson syndrome10.1CRP, CXCL8, IL1B
43gonococcal endophthalmia10.1IL1B, IL6, TNF
44ectodermal dysplasia bartalos type10.1IL1B, IL6, TNF
45stocco dos santos syndrome10.1IL1B, TNF
46mineral metabolism disease10.1IL1B, IL6, TNF
47amyotrophic lateral sclerosis type 1410.1CXCL8, IL1B, TNF
48unilateral multicystic dysplastic kidney10.1CRP, IL6, TNF
49migraine with aura10.1IL1B, IL6, TNF
50bladder signet ring cell adenocarcinoma10.1IL1B, IL6, TNF

Graphical network of the top 20 diseases related to Perinatal Necrotizing Enterocolitis:



Diseases related to perinatal necrotizing enterocolitis

Symptoms & Phenotypes for Perinatal Necrotizing Enterocolitis

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MGI Mouse Phenotypes related to Perinatal Necrotizing Enterocolitis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053876.5CRP, EGF, IL1B, IL6, LY96, PLA2G7

Drugs & Therapeutics for Perinatal Necrotizing Enterocolitis

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Drugs for Perinatal Necrotizing Enterocolitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 224)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Poractant alfaapprovedPhase 426129069-19-8
2
Indomethacinapproved, investigationalPhase 4, Phase 3, Phase 211653-86-13715
Synonyms:
1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid
1z9h
37242-43-6
503560-73-4
53-86-1
74252-25-8 (hydrochloride salt, tri-hydrate)
7681-54-1 (hydrochloride salt)
91853-74-6
AB00052022
AC-532
AC1L1GJQ
AKOS000592893
Aconip
Aconip (TN)
Amuno
Apo-Indomethacin
Arthrexin
Artracin
Artrinovo
Artrivia
BIDD:GT0132
BIM-0050670.0001
BPBio1_000160
BRD-K57222227-001-06-1
BRN 0497341
BSPBio_000144
BSPBio_001149
BSPBio_002176
Bio-0704
Bio2_000405
Bio2_000885
Bonidin
Bonidon
Bonidon Gel
C01926
CAS-53-86-1
CCRIS 3502
CHEBI:49662
CHEMBL6
CID3715
CPD-10545
Catlep
Chibro-amuno
Chrono-indicid
Chrono-indocid
Confortid
D00141
DB00328
DESMETHYL INDOMETHACIN
DivK1c_000271
Dolcidium
Dolcidium PL
Dolovin
Durametacin
EINECS 200-186-5
EU-0100692
Elmetacin
Flexin continus
HMS1362I11
HMS1568H06
HMS1792I11
HMS1920F21
HMS1990I11
HMS2089N19
HMS2091N09
HMS500N13
HSDB 3101
Hicin
I 7378
I0655
I7378_SIGMA
I8280_SIGMA
IDI1_000271
IDI1_002160
IMN
IN1454
Idomethine
Imbrilon
Inacid
Indacin
Indameth
Indmethacine
Indo-Lemmon
Indo-Spray
Indo-phlogont
Indo-rectolmin
Indo-tablinen
Indocid
Indocid (pharmaceutical)
Indocid Pda
Indocid Sr
Indocin
Indocin (TN)
Indocin I.V
Indocin I.V.
Indocin Sr
Indolar SR
Indomecol
Indomed
Indomee
Indomet 140
Indometacin
Indometacin (JP15/INN)
Indometacina
Indometacina [INN-Spanish]
Indometacine
Indometacine [INN-French]
Indometacinum
 
Indometacinum [INN-Latin]
Indometacyna
Indometacyna [Polish]
Indomethacin
Indomethacin & MAP-30
Indomethacin (USP)
Indomethacin [USAN:BAN]
Indomethacin, Indochron E-R, Indocin-SR, Indocid, Indocin, Indomethacin
Indomethacine
Indomethacinum
Indomethancin
Indomethazine
Indomethegan
Indomethine
Indometicina
Indometicina [Spanish]
Indomo
Indomod
Indoptic
Indoptol
Indorektal
Indoxen
Inflazon
Infrocin
Inteban sp
KBio1_000271
KBio2_000489
KBio2_001399
KBio2_003057
KBio2_003967
KBio2_005625
KBio2_006535
KBio3_000897
KBio3_000898
KBio3_001396
KBioGR_000395
KBioGR_000489
KBioSS_000489
KBioSS_001399
L000959
LS-187
LS-82147
Lausit
Liometacen
Lopac-I-7378
Lopac0_000692
MLS000069402
MLS000758212
MLS001074194
Metacen
Metartril
Methazine
Metindol
Mezolin
Miametan
Mikametan
Mobilan
MolMap_000032
MolPort-000-917-894
NCGC00015562-01
NCGC00015562-02
NCGC00015562-03
NCGC00015562-08
NCGC00015562-19
NCGC00024135-02
NCGC00024135-04
NCGC00024135-05
NCGC00024135-06
NCGC00024135-07
NCGC00024135-08
NCGC00024135-09
NCGC00024135-11
NCI-C56144
NCI60_041708
NINDS_000271
Novo-Methacin
Novomethacin
Oprea1_686105
Prestwick0_000272
Prestwick1_000272
Prestwick2_000272
Prestwick3_000272
Prestwick_597
Reumacide
Rhemacin LA
Rheumacin LA
S00108
S1723_Selleck
SMR000058195
SMR000449290
SPBio_000979
SPBio_002363
SPECTRUM1500350
Sadoreum
Spectrum2_000970
Spectrum3_000468
Spectrum4_000018
Spectrum5_000868
Spectrum_000919
Tannex
Tocris-1708
UNII-XXE1CET956
UPCMLD-DP023
UPCMLD-DP023:001
USAN
Vonum
indometacin
indomethacin
nchembio.147-comp11
{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid
3
Nystatinapproved, vet_approvedPhase 4411400-61-911953884
Synonyms:
(1S,15S,16R,17R,18S,19E,21E,25E,27E,29E,31E)-33-[(3-amino-3,6-dideoxy-a-D-mannopyranosyl)oxy]-1,3,4,7,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,25,27,29,31-hexaene-36-carboxylic acid
(1S,15S,16R,17R,18S,19E,21E,25E,27E,29E,31E)-33-[(3-amino-3,6-dideoxy-alpha-D-mannopyranosyl)oxy]-1,3,4,7,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,25,27,29,31-hexaene-36-carboxylic acid
(4E,6E,8E,10E,14E,16E)-3-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-19,25,27,29,32,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,14,16-hexaene-38-carboxylic acid
(4E,6E,8E,10E,14E,16E,18S,19R,20R,21S,35S)-3-[(2S,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-19,25,27,29,32,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,14,16-hexaene-38-carboxylic acid
(4E,6E,8E,10E,14E,16E,18S,19R,21S,35S)-3-[(3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-19,25,27,29,32,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,14,16-hexaene-38-carboxylic acid
AC1NSKG2
AC1NWAPF
AC1O5FWI
AI3-26526
BCBcMAP01_000244
BSPBio_002119
Barstatin 100
Biofanal
C47H75NO17
CHEBI:473992
CHEMBL1200650
CHEMBL229383
CID5311331
CID5702099
CID6433272
Candex Lotion
Candio-hermal
Caswell No. 607B
Comycin
Diastatin
EINECS 215-749-0
EPA Pesticide Chemical Code 202800
Fungicidin
HMS1920D08
HMS2091L08
HMS500N05
HSDB 3138
Herniocid
IDI1_000263
Korostatin
LS-187914
LS-97612
MolPort-003-665-538
MolPort-003-938-857
MolPort-003-983-447
Moronal
Moronal (antibiotic)
Myconystatin
Mycostatin
Mycostatin 20
 
Mycostatin Pastilles
Mykinac
Mykostatyna
N1638_SIGMA
N3503_SIGMA
N4014_SIGMA
N6261_SIGMA
NSC 150817
NYS
Nilstat
Nistatin
Nistatina
Nistatina [INN-Spanish]
Nyamyc
Nyotran
Nystaform
Nystan
Nystatin
Nystatin A
Nystatin A1
Nystatin A1, A2, A3 complex
Nystatin A2
Nystatin A3
Nystatin G
Nystatin LF (liposome)
Nystatin [INN:BAN:JAN]
Nystatin preparation
Nystatine
Nystatine [INN-French]
Nystatinum
Nystatinum [INN-Latin]
Nystatyna
Nystatyna [Polish]
Nystavescent
Nystex
Nystop
O-V Statin
SMP1_000219
SPECTRUM1500446
Spectrum5_001333
Stamicin
Stamycin
Terrastatin
UNII-BDF1O1C72E
UNII-ZGT9EY838C
Zydin E
nystatin
4
Progesteroneapproved, vet_approvedPhase 4, Phase 2, Phase 3, Phase 155957-83-05994
Synonyms:
(S)-4-Pregnene-3,20-dione
(S)-Pregn-4-en-3,20-dione
(S)-Progesterone
.beta.-Progesterone
.delta.(sup4)-Pregnene-3,20-dione
.delta.4-Pregnene-3,20-dione
17.alpha.-Progesterone
17a-Progesterone
17alpha-Progesterone
17alpha-progesterone
17α-progesterone
1dbb
1h60
257630-50-5
3,20-Pregnene-4
32104FB6-BF81-4F6E-83C2-024DEEAEB272
4-Pregnen-3,20-dione
4-Pregnene-3,20-dione
46665_FLUKA
46665_RIEDEL
57-83-0
753497-20-0
8012-32-6
8023-13-0
AC-700
AC1L1LKF
AI3-51682
Agolutin
Akrolutin
BB_NC-0185
BHR-100
BIDD:ER0547
BIDD:PXR0094
BPBio1_000676
BRD-K64994968-001-03-6
BSPBio_000614
Bio-luton
C00410
CCRIS 533
CHEBI:17026
CHEMBL103
CID5994
CIDR
CMC_13406
COL-1620
CPD000058345
Colprosterone
Corlutin
Corlutina
Corluvite
Corporin
Corpus Luteum Hormone
Corpus luteum hormone
Crinone
Crinone (TN)
Crinone progesterone gel
Curretab
Cyclogest
Cyclogesterin
D00066
D4-Pregnene-3,20-dione
DB00396
DR-2011
Delalutin
Delta(4)-pregnene-3,20-dione
Duraprogen
EINECS 200-350-6
ETI-411
EU-0100895
Endometrin
Estima
FE-999913
Flavolutan
Fologenon
Gelbkoerperhormon
Gesterol
Gesterol 100
Gesterol 50
Gestiron
Gestone
Gestormone
Gestron
Glanducorpin
Gynlutin
Gynoluton
Gynolutone
HMS1569O16
HMS2051O05
HMS2090J07
HSDB 3389
Hormoflaveine
Hormoluton
Hydroxyprogesterone Caproate
Hydroxyprogesterone Caproic acid
LMST02030159
LS-234
Lingusorbs
Lipo-Lutin
Lipolutin
Lopac0_000895
Lucorteum
Lucorteum Sol
Lucorteum sol
Lugesteron
Luteal hormone
Luteinique
Luteocrin normale
Luteodyn
Luteogan
Luteohormone
Luteol
Luteol (VAN)
Luteopur
Luteosan
Luteostab
Luteovis
Luteum
Lutex
Lutidon
Lutin
Lutinus
Lutociclina
Lutocuclin M
Lutocyclin
Lutocyclin M
 
Lutocyclin m
Lutocylin
Lutocylol
Lutoform
Lutogyl
Lutogynon
Lutren
Lutromone
MLS000028517
MLS000758277
MLS001074187
MLS002222367
MPA
Membrettes
Methylpregnone
Micronized Progesterone
MolPort-001-794-643
NCGC00022185-03
NCGC00022185-04
NCGC00022185-05
NCGC00022185-06
NCGC00022185-07
NCGC00022185-08
NCGC00022185-09
NCGC00090798-01
NCGC00090798-02
NCI60_042166
NSC 64377
NSC 9704
NSC-9704
NSC64377
NSC9704
Nalutron
Natural Progesterone
P 0130
P0130_SIGMA
P0478
P3972_SIGMA
P6149_SIGMA
P7556_ALDRICH
P7556_SIGMA
P8783_SIGMA
P9776_SIGMA
PROGESTERONE
Percutacrine
Percutacrine Luteinique
Piaponon
Pranone
Pregn-4-en-3,20-dione
Pregn-4-ene-3,20-dione
Pregnene-3,20-dione
Pregnenedione
Prestwick0_000477
Prestwick1_000477
Prestwick2_000477
Prestwick3_000477
Prestwick_411
Primolut
Prochieve
Progeffik
Progekan
Progestan
Progestasert
Progesterol
Progesteron
Progesterona
Progesterona [INN-Spanish]
Progesterone
Progesterone (JP15/USP/INN)
Progesterone [INN:BAN:JAN]
Progesterone [Progestins]
Progesterone, water-soluble
Progesterone-Water Soluble
Progesterone: HBC complex
Progesteronum
Progesteronum [INN-Latin]
Progestin
Progestogel
Progestol
Progeston
Progestone
Progestosol
Progestrel
Progestron
Progestronol
Progestérone
Projestaject
Prolets
Prolidon
Prolutin
Proluton
Prolutone
Prometrium
Prometrium (TN)
Prontogest
Protormone
S00293
S1705_Selleck
SAM001247039
SMR000058345
SMR000653542
SPBio_002553
SR-01000000088
SR-01000000088-5
Spectrum5_002053
Syngesterone
Syngestrets
Synovex S
Syntolutan
U 3672
UNII-4G7DS2Q64Y
Utrogest
Utrogestan
Vitarrine
WLN: L E5 B666 OV MUTJ A1 E1 FV1
ZINC04428529
beta-Progesterone
bmse000482
component of Cyclogesterin
corpus luteum hormone
delta(4)-Pregnene-3,20-dione
delta(Sup 4)-Pregnene-3,20-dione
delta(Sup4)-pregnene-3,20-dione
delta(sup 4)-Pregnene-3,20-dione
delta4-Pregnene-3,20-dione
luteohormone
nchembio.2007.53-comp14
5
Miconazoleapproved, investigational, vet_approvedPhase 4, Phase 3370622916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
6
IbuprofenapprovedPhase 4, Phase 3, Phase 2, Phase 151815687-27-13672
Synonyms:
(4-isobutylphenyl)-α-methylacetic acid
(RS)-ibuprofen
(±)-2-(p-isobutylphenyl)propionic acid
(±)-ibuprofen
(±)-p-isobutylhydratropic acid
(±)-α-methyl-4-(2-methylpropyl)benzeneacetic acid
139466-08-3
15687-27-1
2-(4-isobutylphenyl)propanoic acid
4-isobutylhydratropic acid
58560-75-1
AC-11312
AC1L1GGE
AC1Q1P84
AC1Q1P85
ACHES-N-PAIN
ARONIS23835
Act-3
Actiprofen
Adex 200
Adran
Advil
Advil (TN)
Advil Liqui-Gels
Ak+C2278tren
Alaxan
Algofen
Am-Fam 400
Amelior
Amersol
Amibufen
Anafen
Anco
Andran
Anflagen
Antagil
Antalfene
Antarene
Antiflam
Apo-Ibuprofen
Apsifen
Apsifen-F
Artofen
Artril
Artril 300
BB_SC-1358
BIDD:GT0050
BRN 2049713
Balkaprofen
Betaprofen
Bloom
Bluton
Brofen
Brufanic
Brufen
Brufen 400
Bruflam
Brufort
Buburone
Bufeno
Bufigen
Bukrefen
Bupron
Buracaps
Burana
Butylenin
C01588
C13H18O2
CCRIS 3223
CHEBI:5855
CHEMBL521
CID3672
CPD000058184
Cap-Profen
Carol
Cesra
Children's Advil
Children's Elixsure
Children's Ibuprofen
Children's Motrin
Citalgan
Cobo
Codral
Combiflam
Cunil
D00126
D007052
DB01050
DOLO PUREN
Daiprophen
Dalsy
Dansida
Deep Relief
Dentigoa
Dibufen
Dignoflex
Dolgin
Dolgirid
Dolgit
Dolibu
Dolmaral
Dolo-Dolgit
Dolocyl
Dolofen
Dolofen-F
Dolofin
Dolofort
Dologel
Dolomax
Doloren
Dolormin
Doltibil
Dolven
Donjust B
Dorival
Drin
Duafen
Duobrus
Dura-Ibu
Duralbuprofen
Dysdolen
EU-0100691
Easifon
Ebufac
Emflam
Emflam-200
Emodin
Epobron
Eputex
Ergix
Esprenit
Exneural
Faspic
Femadon
Femafen
Femapirin
Femidol
Fenbid
Fenbid Spansule
Fendol
Fenspan
Fibraflex
Gelufene
Gofen
Grefen
Gynofug
HMS1920F15
HMS2089P05
HMS2091N03
HMS502M09
HSDB 3099
Haltran
I 4883
I01-7039
I0415
I4883_SIGMA
I7905_SIAL
IB-100
IDI1_000887
IP 82
IP-82
IP82
Ibol
Ibren
Ibu
Ibu-Attritin
Ibu-Slo
Ibu-Tab
Ibu-Tab 200
Ibu-slo
Ibu-slow
Ibubest
Ibubeta
Ibucasen
Ibudol
Ibudolor
 
Ibufen
Ibuflamar
Ibufug
Ibugel
Ibugen
Ibugesic
Ibuhexal
Ibulagic
Ibular
Ibulav
Ibuleve
Ibulgan
Ibumed
Ibumerck
Ibumetin
Ibupirac
Ibuprin
Ibuprocin
Ibuprofene
Ibuprofeno
Ibuprofenum
Ibuprohm
Ibuprophen
Ibusal
Ibutid
Ifen
Inabrin
Inflam
Inoven
Ipren
Irfen
Isodol
Jenaprofen
Junifen
Junior Strength Advil
Junior Strength Ibuprofen
Junior Strength Motrin
KBio1_000887
KBio2_001329
KBio2_003897
KBio2_006465
KBio3_001390
Kesan
Kratalgin
LS-7454
Lamidon
Lebrufen
Librofem
Lidifen
Liptan
Lopane
MLS000069733
MLS001146965
Malafene
Manypren
Medipren
Melfen
Mensoton
Midol
Midol 200
Moment
Motrin
Motrin (TN)
Motrin IB
Mynosedin
NCI60_002065
NINDS_000887
NSC 256857
NSC256857
Nagifen-D
Napacetin
Narfen
Neo-Helvagit
Neo-Mindol
NeoProfen
Neobrufen
Nerofen
Noalgil
Nobafon
Nobfelon
Nobfen
Nobgen
Noritis
Norton
Novadol
Novo-Profen
Novogent
Novogent N
Novoprofen
Nuprilan
Nuprin
Nurofen
Optifen
Opturem
Oralfene
Ostarin
Ostofen
Ozonol
P-Isobutylhydratropic Acid
Paduden
Panafen
Pantrop
Para-Isobutylhydratropic Acid
Paxofen
Pedia-Profen
PediaProfen
Pediaprofen
Pediatric Advil
Perofen
Proartinal
Profen
Proflex
Provon
Quadrax
R.D. 13621
RD 13621
Rafen
Ranofen
Rebugen
Relcofen
Rhinadvil
Rofen
Roidenin
Rufen
Rufin
Rupan
SAM002264619
SMR000058184
SPBio_000178
STK177358
Sadefen
Salivia
Salprofen
Seclodin
Sednafen
Seklodin
Seskafen
Siyafen
Solpaflex
Solufen
Stelar
Sugafen
Suprafen
Suspren
Syntofene
TL8001184
Tab-Profen
Tabalon
Tabalon 400
Tatanal
Tempil
Tofen
Togal N
Tonal
Trendar
U 18573
U-18,573
U-18573
UCB 79171
Unipron
Upfen
Uprofen
Urem
VUFB 9649
Zafen
Zofen
alpha-(4-Isobutylphenyl)propionate
alpha-(4-Isobutylphenyl)propionic acid
alpha-p-Isobutylphenylpropionate
alpha-p-Isobutylphenylpropionic acid
ibuprofen
p-Isobutyl-2-phenylpropionate
p-Isobutyl-2-phenylpropionic acid
p-Isobutylhydratropate
p-Isobutylhydratropic acid
α-(4-isobutylphenyl)propionic acid
α-(p-isobutylphenyl)propionic acid
7
Caffeineapproved, NutraceuticalPhase 4, Phase 339658-08-22519
Synonyms:
07E4FB58-FD79-4175-8E3D-05BF96954522
1,3,7-Trimethyl-2,6-dioxopurine
1,3,7-Trimethyl-3,7-dihydro-1H-purine-2,6-dione
1,3,7-Trimethylpurine-2,6-dione
1,3,7-Trimethylxanthine
1,3,7-trimethyl-2,6-dioxopurine
1,3,7-trimethylpurine-2,6-dione
1,3,7-trimethylxanthine
1-3-7-TRIMETHYLXANTHINE
1-Methyl-Theobromine
1-methyltheobromine
137X
1gfz
1l5q
1l7x
27602_FLUKA
2a3b
3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion
3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
3,7-dihydro-1,3,7-trimethyl-1H-purine
5-26-13-00558 (Beilstein)
58-08-2
7-Methyl Theophylline
7-Methyltheophylline
7-methyltheophylline
71701-02-5
75035_FLUKA
95789-13-2
A.S.A. and Codeine Compound
AC-12774
AC1L1DV2
AC1Q3Z23
ACon1_000085
AI3-20154
AKOS000121334
Alert-Pep
Alert-pep
Anacin Maximum Strength
Anhydrous caffeine
Anhydrous caffeine (JP15)
Anhydrous caffeine (TN)
Anoquan
BIDD:ER0554
BIDD:GT0632
BIDD:PXR0172
BIM-0050216.0001
BRD-K02404261-001-02-7
BRD-K02404261-001-03-5
BRN 0017705
BSPBio_001921
Berlin-Chemie Brand of Caffeine
Bio-0579
Bio1_000473
Bio1_000962
Bio1_001451
Bristol-Myers Squibb Brand of Caffeine
C 0750
C07481
C0750_SIAL
C1778_SIAL
C2042
C6035_FLUKA
C6035_SIGMA
C7731_SIAL
C8960_SIAL
CCRIS 1314
CFF
CHEBI:27732
CHEMBL113
CID2519
CU-01000012617-3
Cafamil
Cafcit
Cafecon
Cafeina
Cafergot
Cafeína
Caffedrine
Caffedrine Caplets
Caffein
Caffeina
Caffeina [Italian]
Caffeine (USP)
Caffeine (natural)
Caffeine Pure
Caffeine [BAN:JAN]
Caffeine solution
Caffeine, Anhydrous
Caffeine, Monohydrate
Caffeine, Synthetic
Caffeine, anhydrous
Caffeine, synthetic
Caffeinum
Caffine
Cafipel
Caféine
Coffein
Coffein [German]
Coffeine
Coffeinum
Coffeinum N
Coffeinum Purrum
Compound 65
D002110
D00528
DB00201
DHC Plus
DHCplus
Darvon Compound
Darvon Compound-65
Dasin
Dexitac
Dexitac Stay Alert Stimulant
Dhc Plus
Diurex
DivK1c_000730
Durvitan
EINECS 200-362-1
EU-0100228
Eldiatric C
Enerjets
Ercatab
Esgic
Esgic-Plus
FEMA No. 2224
Femcet
Fioricet
Fiorinal
GlaxoSmithKline Brand of Caffeine
Guaranine
HMS1920I09
HMS2091O11
HMS502E12
HSDB 36
Hycomine
Hycomine Compound
I14-4386
 
IDI1_000730
Invagesic
Invagesic Forte
KBio1_000730
KBio2_001781
KBio2_004349
KBio2_006917
KBio3_001141
KBioGR_002325
KBioSS_001781
Keep Alert
Kofein
Kofein [Czech]
Koffein
Koffein [German]
L000155
LS-237
Lanorinal
Lopac-C-0750
Lopac0_000228
MEGxp0_001350
MLS001055341
MLS001056714
MLS001066409
Mateina
Mateína
Maximum Strength Snapback Stimulant Powders
Medigesic Plus
Merck dura Brand of Caffeine
Methyltheobromide
Methyltheobromine
Methylxanthine theophylline
Midol Maximum Strength
Migergot
Miudol
MolMap_000054
MolPort-000-730-850
Monohydrate Caffeine
Monomethyl Derivative of Theophylline
Monomethyl derivative of Theophylline
NCGC00015208-01
NCGC00015208-02
NCGC00015208-04
NCGC00015208-14
NCGC00090699-01
NCGC00090699-02
NCGC00090699-03
NCGC00090699-04
NCGC00090699-05
NCGC00090699-06
NCGC00090699-07
NCGC00090699-08
NCGC00090699-09
NCGC00168808-01
NCGC00168808-02
NCI-C02733
NCIOpen2_008255
NINDS_000730
NSC 5036
NSC5036
Natural Caffeinum
Nix Nap
No Doz
No-Doz
Nodaca
Nodoz Maximum Strength Caplets
Norgesic
Norgesic Forte
Organex
Orphengesic
Orphengesic Forte
P-A-C Analgesic Tablets
PDSP1_001016
PDSP1_001235
PDSP2_001000
PDSP2_001219
Passauer Brand of Caffeine
Pep-Back
Percoffedrinol N
Percutafeine
Phensal
Pierre Fabre Brand of Caffeine
Probes1_000150
Probes2_000128
Propoxyphene
Propoxyphene Compound 65
Propoxyphene Compound-65
Quick Pep
Quick-Pep
Refresh'n
Republic Drug Brand of Caffeine
SDCCGMLS-0064595.P001
SDCCGMLS-0064595.P002
SK 65 Compound
SK-65 Compound
SMR000326667
SPBio_001222
SPECTRUM1500155
STK177283
Seid Brand of Caffeine
Spectrum2_001261
Spectrum3_000321
Spectrum4_001782
Spectrum5_000423
Spectrum_001301
Stim
Synalgos-Dc
TNP00310
Thein
Theine
Theobromine ME
Theobromine Me
Theophylline ME
Theophylline Me
Theophylline, 7-methyl
Thompson Brand 1 of Caffeine
Thompson Brand 2 of Caffeine
Tirend
Tri-Aqua
Triad
UNII-3G6A5W338E
Ultra Pep-Back
Vivarin
W222402_ALDRICH
WLN: T56 BN DN FNVNVJ B1 F1 H1
Wake-Up
Wigraine
Xanthine, 1,3,7-trimethyl
ZINC00001084
bmse000206
cafeine
caffeine
caffenium
component of Cafergot
nchembio.243-comp7
nchembio.63-comp5
nchembio774-comp2
teina
teína
8Phosphodiesterase InhibitorsPhase 4, Phase 3, Phase 21289
9Calcium, DietaryPhase 4, Phase 3, Phase 25713
10Respiratory System AgentsPhase 4, Phase 3, Phase 2, Phase 14997
11Tocolytic AgentsPhase 4, Phase 3, Phase 2739
12Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 2, Phase 3, Phase 113168
13Hormone AntagonistsPhase 4, Phase 2, Phase 3, Phase 113180
14HormonesPhase 4, Phase 2, Phase 3, Phase 114415
15Peripheral Nervous System AgentsPhase 4, Phase 3, Phase 2, Phase 123689
16Pulmonary SurfactantsPhase 4, Phase 3, Phase 2111
17Analgesics, Non-NarcoticPhase 4, Phase 3, Phase 2, Phase 16501
18Anti-Inflammatory AgentsPhase 4, Phase 3, Phase 2, Phase 110729
19Anti-Inflammatory Agents, Non-SteroidalPhase 4, Phase 3, Phase 2, Phase 14443
20Antirheumatic AgentsPhase 4, Phase 3, Phase 2, Phase 110956
21AnalgesicsPhase 4, Phase 3, Phase 2, Phase 111733
22Cyclooxygenase InhibitorsPhase 4, Phase 3, Phase 2, Phase 12870
23Antibiotics, AntitubercularPhase 4, Phase 3, Phase 2, Phase 17180
24ProgestinsPhase 4, Phase 2, Phase 3, Phase 1564
25cadexomer iodinePhase 4537
26Trace ElementsPhase 4, Phase 3, Phase 26001
27Antitubercular AgentsPhase 4, Phase 3, Phase 21343
28MicronutrientsPhase 4, Phase 3, Phase 26001
29
IodinePhase 45707553-56-2807
Synonyms:
I2
Iode
Iodine-molecule
 
Iodio
Iodum
Jod
Jood
Tincture iodine
30EstrogensPhase 4, Phase 2, Phase 3, Phase 12542
31Anti-Infective Agents, LocalPhase 41880
32Neurotransmitter AgentsPhase 4, Phase 3, Phase 2, Phase 118340
33IonophoresPhase 448
34AnticoagulantsPhase 4, Phase 32623
35Caffeine citratePhase 4, Phase 320
36Antifungal AgentsPhase 4, Phase 33696
37Anti-Bacterial AgentsPhase 4, Phase 3, Phase 1, Phase 211226
38Anti-Infective AgentsPhase 4, Phase 3, Phase 1, Phase 222062
39LactoferrinPhase 451
40Estrogen AntagonistsPhase 4, Phase 2, Phase 3, Phase 11349
41Central Nervous System StimulantsPhase 4, Phase 32211
42Chelating AgentsPhase 4, Phase 31423
4317-alpha-hydroxy-progesterone caproatePhase 4, Phase 2, Phase 3, Phase 132
44Purinergic P1 Receptor AntagonistsPhase 4, Phase 3360
4511-hydroxyprogesteronePhase 4, Phase 2, Phase 3, Phase 132
46AcidophilusNutraceuticalPhase 4, Phase 3, Phase 2558
47BifidobacteriumNutraceuticalPhase 4, Phase 3, Phase 2247
48CaproateNutraceuticalPhase 4, Phase 2, Phase 3, Phase 135
49
Citric Acidnutraceutical, vet_approvedPhase 4, Phase 3, Phase 2116077-92-9311
Synonyms:
2-Hydroxy-1,2,3-propanetricarboxylate
2-Hydroxy-1,2,3-propanetricarboxylic acid
2-Hydroxytricarballylic acid
3-Carboxy-3-hydroxypentane-1,5-dioate
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Aciletten
Anhydrous citrate
Anhydrous citric acid
Chemfill
Citraclean
 
Citrate
Citretten
Citric acid
Citro
Citronensäure
E 330
Hydrocerol A
Kyselina citronova
Suby G
Uro-trainer
beta-Hydroxytricarballylate
beta-Hydroxytricarballylic acid
50CitrateNutraceuticalPhase 4, Phase 3, Phase 21160

Interventional clinical trials:

(show top 50)    (show all 290)
idNameStatusNCT IDPhase
1Withholding Feeds During Red Blood Cell Transfusion and TRAGIUnknown statusNCT02132819Phase 4
2The Effect of Probiotics on Exacerbation of Inflammatory Bowel Disease Exacerbation (Crohn's Disease)Unknown statusNCT01765998Phase 4
3Cpap at Delivery Room for Preterm InfantsUnknown statusNCT01024361Phase 4
4Intragastric and Peritoneal Microdialysis in Infants With Necrotizing Enterocolitis (NEC)CompletedNCT00332592Phase 4
5Probiotics to Prevent NEC - a Historical Control StudyCompletedNCT01670916Phase 4
6Early Versus Late Lactoferrin in Prevention of Neonatal SepsisCompletedNCT02959229Phase 4
7Comparison of Lactobacillus Reuteri and Nystatin Prophylaxis on Candida Colonization and Infection in Very Low Birth Weight InfantsCompletedNCT01531192Phase 4
8Ibuprofen and Renal Function in Premature InfantsCompletedNCT00217191Phase 4
9MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose CaffeineCompletedNCT00809055Phase 4
10Efficacy of 17 Alpha-hydroxyprogesterones Caproate for the Prevention of Preterm DeliveryCompletedNCT00331695Phase 4
11Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part IVCompletedNCT01604447Phase 4
12Evaluate the Use of Plastic Bags in Preventing and Treating Hypothermia in NeonatesCompletedNCT01403623Phase 4
13A Randomised Controlled Trial of Iodide Supplementation in Preterm Infants Follow-up at 2 YearsCompletedNCT00638092Phase 4
14Impact of Oral Application of Gastrografin on the Meconium Evacuation in Very Low Birth Weight InfantsCompletedNCT01515696Phase 4
15OPTIMIST-A Trial: Minimally-invasive Surfactant Therapy in Preterm Infants 25-28 Weeks Gestation on CPAPRecruitingNCT02140580Phase 4
16Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part IIRecruitingNCT01604421Phase 4
17Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part IRecruitingNCT01604317Phase 4
18Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part IIIRecruitingNCT01604434Phase 4
19Removal Versus Retention of Cerclage in Preterm Premature Rupture of Membranes (PPROM)TerminatedNCT00201656Phase 4
20Sodium Supplementation and Growth in Very Low Birth Weight InfantsTerminatedNCT01795638Phase 4
21RCT of Postoperative Infections Following Caesarean Section Infections Following Caesarean SectionWithdrawnNCT02009098Phase 4
22Comparing Ibuprofen And Indomethacin For The Treatment Of The Patent Ductus Arteriosus in Very Premature BabiesWithdrawnNCT00470743Phase 4
23Effect of Saccharomyces Boulardii on Necrotizing Enterocolitis in Very Low Birth Weight InfantsUnknown statusNCT01315821Phase 3
24Randomized Study of Pessary Versus Standard Management in Women With Increased Chance of Premature BirthUnknown statusNCT00735137Phase 3
25Cysteine Supplementation in Critically Ill NeonatesUnknown statusNCT00254176Phase 2, Phase 3
26Efficacy Study of Hypothermia Plus Magnesium Sulphate(MgSO4) in the Management of Term and Near Term Babies With Hypoxic Ischemic EncephalopathyUnknown statusNCT01646619Phase 3
27Lactobacillus Reuteri for Prevention of Necrotizing Enterocolitis in Very Low-birth Weight InfantsCompletedNCT01531179Phase 3
28Probiotics in the Management of Necrotizing Enterocolitis in HIV-exposed Premature InfantsCompletedNCT01868737Phase 3
29The Efficacy of Symbiotic on CytokinesCompletedNCT01899677Phase 3
30Role of Probiotics for Prevention of NEC in Preterm VLBW InfantsCompletedNCT02650869Phase 3
31Effect of Oral Probiotic Supplementation on The Rate of Hospital Acquired Infection and Necrotizing Enterocolitis in Preterm Very Low Birth Weight InfantsCompletedNCT01340469Phase 3
32Effect of Vitamin A in the Treatment of Neonatal Sepsis and Necrotizing EnterocolitisCompletedNCT00707785Phase 3
33A Single Blinded Study on the Effect of Saccharomyces Boulardii CNCM I-745 on Growth and Development in Preterm InfantsCompletedNCT02310425Phase 3
34Prevention Trial of Nosocomial Infections in Neutropenic Prematures With G-CSFCompletedNCT00213759Phase 3
35Progesterone Vaginal Pessary for Prevention of Preterm Twin BirthCompletedNCT02350231Phase 2, Phase 3
36Ursodiol for Treating Parenteral Nutrition Associated Cholestasis in NeonatesCompletedNCT00846963Phase 2, Phase 3
37Trial of Indomethacin Prophylaxis in Preterm Infants (TIPP)CompletedNCT00009646Phase 3
38Intravenous Immunoglobulin in Prevention of Preterm Neonatal SepsisCompletedNCT02954926Phase 3
39PREGNANT Short Cervix TrialCompletedNCT00615550Phase 3
40Intravenous Immune Globulin (IVIG) to Prevent Neonatal InfectionCompletedNCT01203345Phase 2, Phase 3
4117OHP for Reduction of Neonatal Morbidity Due to Preterm Birth (PTB) in Twin and Triplet PregnanciesCompletedNCT00163020Phase 2, Phase 3
42Caffeine for Apnea of Prematurity (CAP)CompletedNCT00182312Phase 3
43NIV Strategies for RDS in Preterm Infants. NIV (Non Invasive Ventilation), RDS (Respiratory Distress Syndrome)CompletedNCT02259400Phase 2, Phase 3
44Fluconazole Prophylaxis for the Prevention of Candidiasis in Infants Less Than 750 Grams BirthweightCompletedNCT00734539Phase 3
45Glutamine Supplementation to Prevent Death or Infection in Extremely Premature InfantsCompletedNCT00005775Phase 3
46Canadian Oxygen Trial (COT)CompletedNCT00637169Phase 3
47Nasal Intermittent Positive Pressure Ventilation in Premature Infants (NIPPV)CompletedNCT00433212Phase 3
48Pentoxifylline and Late Onset Sepsis in Preterm InfantsCompletedNCT02163174Phase 3
49High Versus Low Dose of Caffeine for Apnea of PrematurityCompletedNCT02103777Phase 3
50Omega-3 Fatty Acid Supplementation to Prevent Preterm Birth in High Risk PregnanciesCompletedNCT00135902Phase 3

Search NIH Clinical Center for Perinatal Necrotizing Enterocolitis


Cochrane evidence based reviews: enterocolitis, necrotizing

Genetic Tests for Perinatal Necrotizing Enterocolitis

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Anatomical Context for Perinatal Necrotizing Enterocolitis

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Publications for Perinatal Necrotizing Enterocolitis

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Variations for Perinatal Necrotizing Enterocolitis

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Expression for genes affiliated with Perinatal Necrotizing Enterocolitis

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Search GEO for disease gene expression data for Perinatal Necrotizing Enterocolitis.

Pathways for genes affiliated with Perinatal Necrotizing Enterocolitis

About this section

Pathways related to Perinatal Necrotizing Enterocolitis according to GeneCards Suite gene sharing:

(show top 50)    (show all 62)
idSuper pathwaysScoreTop Affiliating Genes
19.7IL1B, IL6
29.7LY96, TLR4
3
Show member pathways
9.6CXCL8, EGF, HBEGF
49.6EGF, IL6, TLR4
59.5IL1B, TNF
69.5HBEGF, IL1B, PLA2G7
79.5CXCL8, HBEGF, IL6
8
Show member pathways
9.4IL1B, IL6, TLR4
99.4HBEGF, IL6, TNF
109.4EGF, HBEGF, IL6, THPO
119.3CXCL8, IL1B, IL6
129.3IL6, THPO, TNF
139.3IL6, TLR4, TNF
149.3IL1B, TLR4, TNF
159.2IL1B, IL6, TNF
169.2IL1B, IL6, TNF
179.2IL1B, IL6, TNF
189.2IL1B, IL6, TNF
199.2IL1B, IL6, TNF
209.2IL1B, IL6, TNF
219.2IL1B, IL6, TNF
229.1LY96, TLR4, TNF
239.1LY96, TLR4, TNF
249.1EGF, IL6, TLR4, TNF
25
Show member pathways
9.1CXCL8, IL1B, IL6, TLR4
26
Show member pathways
9.0CXCL8, IL6, LY96, TLR4
278.9IL1B, IL6, THPO, TNF
288.9IL1B, IL6, TLR4, TNF
29
Show member pathways
8.9IL1B, IL6, TLR4, TNF
308.9IL1B, IL6, TLR4, TNF
31
Show member pathways
8.9IL1B, IL6, TLR4, TNF
32
Show member pathways
8.8CXCL8, IL1B, IL6, TNF
338.8CXCL8, IL1B, IL6, TNF
34
Show member pathways
8.8CXCL8, IL1B, IL6, TNF
358.8CXCL8, IL1B, IL6, TNF
36
Show member pathways
8.8CXCL8, IL1B, IL6, TNF
378.8CXCL8, IL1B, IL6, TNF
388.8CXCL8, IL1B, IL6, TNF
398.8CXCL8, IL1B, IL6, TNF
408.8CRP, CXCL8, IL6, TNF
41
Show member pathways
8.7CRP, IL1B, IL6, TNF
42
Show member pathways
8.7IL1B, LY96, TLR4, TNF
438.6CXCL8, EGF, IL1B, IL6, TNF
448.5CXCL8, IL1B, IL6, TLR4, TNF
458.5CXCL8, IL1B, IL6, TLR4, TNF
468.5CXCL8, IL1B, IL6, TLR4, TNF
478.5CXCL8, IL1B, IL6, TLR4, TNF
488.5CXCL8, IL1B, IL6, TLR4, TNF
49
Show member pathways
8.5CXCL8, IL1B, IL6, TLR4, TNF
50
Show member pathways
8.4CXCL8, IL6, LY96, TLR4, TNF

GO Terms for genes affiliated with Perinatal Necrotizing Enterocolitis

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Cellular components related to Perinatal Necrotizing Enterocolitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1lipopolysaccharide receptor complexGO:00466969.7LY96, TLR4
2extracellular regionGO:00055767.5CRP, CXCL8, EGF, HBEGF, IL1B, IL6
3extracellular spaceGO:00056156.6CRP, CXCL8, EGF, HBEGF, IL1B, IL6

Biological processes related to Perinatal Necrotizing Enterocolitis according to GeneCards Suite gene sharing:

(show all 45)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of ERBB signaling pathwayGO:190118510.7EGF, HBEGF
2detection of lipopolysaccharideGO:003249710.4LY96, TLR4
3MyD88-independent toll-like receptor signaling pathwayGO:000275610.4LY96, TLR4
4necroptotic processGO:007026610.4LY96, TLR4
5negative regulation of MyD88-independent toll-like receptor signaling pathwayGO:003412810.4LY96, TLR4
6epithelial cell proliferation involved in salivary gland morphogenesisGO:006066410.4IL6, TNF
7positive regulation of interleukin-8 biosynthetic processGO:004541610.4TLR4, TNF
8embryonic digestive tract developmentGO:004856610.3CXCL8, TNF
9positive regulation of peptidyl-tyrosine phosphorylationGO:005073110.3EGF, HBEGF, IL6
10negative regulation of lipid catabolic processGO:005099510.3IL1B, TNF
11positive regulation of calcidiol 1-monooxygenase activityGO:006055910.3IL1B, TNF
12positive regulation of chemokine biosynthetic processGO:004508010.3IL1B, TNF
13positive regulation of fever generationGO:003162210.3IL1B, TNF
14positive regulation of heterotypic cell-cell adhesionGO:003411610.2IL1B, TNF
15negative regulation of chemokine biosynthetic processGO:004507910.2IL6, SIGIRR
16positive regulation of membrane protein ectodomain proteolysisGO:005104410.2IL1B, TNF
17regulation of establishment of endothelial barrierGO:190314010.1IL1B, TNF
18regulation of I-kappaB kinase/NF-kappaB signalingGO:004312210.1IL1B, TNF
19positive regulation of chemokine productionGO:003272210.1IL6, TLR4, TNF
20positive regulation of smooth muscle cell proliferationGO:004866110.0HBEGF, IL6, TNF
21positive regulation of interferon-gamma productionGO:003272910.0IL1B, TLR4, TNF
22positive regulation of interleukin-8 productionGO:003275710.0IL1B, TLR4, TNF
23positive regulation of JNK cascadeGO:00463309.9IL1B, TLR4, TNF
24positive regulation of NF-kappaB import into nucleusGO:00423469.9IL1B, TLR4, TNF
25defense response to Gram-positive bacteriumGO:00508309.9CRP, IL6, TNF
26apoptotic signaling pathwayGO:00971909.9LY96, TLR4, TNF
27I-kappaB kinase/NF-kappaB signalingGO:00072499.9LY96, TLR4, TNF
28negative regulation of lipid storageGO:00108889.9CRP, IL6, TNF
29sequestering of triglycerideGO:00307309.9IL1B, TNF
30acute-phase responseGO:00069539.8CRP, IL6, SIGIRR
31positive regulation of sequence-specific DNA binding transcription factor activityGO:00510919.8IL1B, IL6, TNF
32MAPK cascadeGO:00001659.8EGF, HBEGF, IL1B, TNF
33positive regulation of ERK1 and ERK2 cascadeGO:00703749.8IL6, THPO, TLR4, TNF
34activation of MAPK activityGO:00001879.8EGF, IL1B, TLR4, TNF
35positive regulation of protein kinase B signalingGO:00518979.7HBEGF, IL6, THPO, TNF
36toll-like receptor 4 signaling pathwayGO:00341429.7LY96, TLR4
37positive regulation of interleukin-6 productionGO:00327559.6IL1B, IL6, TLR4, TNF
38positive regulation of NF-kappaB transcription factor activityGO:00510929.6IL1B, IL6, TLR4, TNF
39positive regulation of nitric oxide biosynthetic processGO:00454299.6IL1B, IL6, TLR4, TNF
40lipopolysaccharide-mediated signaling pathwayGO:00316639.5IL1B, LY96, TLR4, TNF
41immune responseGO:00069559.3CXCL8, IL1B, IL6, TLR4, TNF
42response to lipopolysaccharideGO:00324969.3IL1B, IL6, LY96, TLR4
43cellular response to lipopolysaccharideGO:00712229.2CXCL8, IL6, LY96, TLR4, TNF
44positive regulation of gene expressionGO:00106289.2CRP, IL1B, IL6, TLR4, TNF
45inflammatory responseGO:00069548.3CRP, CXCL8, IL1B, IL6, LY96, TLR4

Molecular functions related to Perinatal Necrotizing Enterocolitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1lipopolysaccharide receptor activityGO:00018759.7LY96, TLR4
2growth factor activityGO:00080839.5EGF, HBEGF, IL6, THPO
3cytokine activityGO:00051259.1CXCL8, IL1B, IL6, THPO, TNF

Sources for Perinatal Necrotizing Enterocolitis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet