MCID: PRN007
MIFTS: 33

Perinephritis malady

Summaries for Perinephritis

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32MalaCards
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MalaCards: Perinephritis is related to adenoma and sarcoma. An important gene associated with Perinephritis is MDM2 (MDM2 oncogene, E3 ubiquitin protein ligase), and among its related pathways is Tryptophan metabolism. The compounds 2-chlorodeoxyadenosine and ifosfamide have been mentioned in the context of this disorder. Affiliated tissues include kidney, smooth muscle and colon, and related mouse phenotype renal/urinary system.

Aliases & Classifications for Perinephritis

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8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 34MeSH
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Aliases & Descriptions:

perinephritis 8 10 60


External Ids:

Disease Ontology8 DOID:2982
SNOMED-CT56 111404004
MeSH34 D010501

Related Diseases for Perinephritis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Perinephritis:



Diseases related to perinephritis

Clinical Features for Perinephritis

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Drugs & Therapeutics for Perinephritis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Perinephritis

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Anatomical Context for Perinephritis

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32MalaCards
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MalaCards organs/tissues related to Perinephritis:

32
Kidney, Smooth muscle, Colon, Skeletal muscle, B cells, Lymph node

Animal Models for Perinephritis or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Perinephritis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.2ALB, KRT7, MDM2, CSF3

Publications for Perinephritis

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50PubMed
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Articles related to Perinephritis:

(show top 50)    (show all 81)
idTitleAuthorsYear
1
Nephrogenic adenoma: a report of 3 unusual cases infiltrating into perinephric adipose tissue. (23426119)
2013
2
Perinephric extramedullary haematopoiesis in primary myelofibrosis. (22329535)
2012
3
Cystitis, pyelonephritis and perinephric abscess due to ureaplasma urealyticum. (23000853)
2012
4
Radiology-pathology conference: primary perinephric and renal extraosseous Ewing's sarcoma. (22226450)
2012
5
Stage pT3a of renal clear cell carcinoma: do tumors with sinus fat involvement behave the same as those with perinephric fat involvement? (21655644)
2011
6
Urgent referrals. Eczema herpeticum, pemphigus vulgaris, perinephric abscess, quinsy, necrotising fasciitis. (21510509)
2011
7
Waldenstrom's macroglobulinemia presenting as a perinephric mass. (21944982)
2011
8
A case of perinephric liposarcoma which recurred ten years later from the initial operation. (21372501)
2011
9
Case report: Perinephric lymphangiomatosis. (21042452)
2010
10
Computed tomography findings in bilateral perinephric lymphangiomatosis. (20842254)
2010
11
Pseudosarcomatous fibroblastic/myofibroblastic proliferation in perinephric adipose tissue adjacent to renal cell carcinoma: a lesion mimicking well-differentiated liposarcoma. (19525929)
2009
12
Bilateral perinephric diffuse large B-cell lymphoma and synchronous renal oncocytoma. (18364624)
2008
13
Pyomyositis with hepatic and perinephric abscesses caused by Candida albicans in a diabetic nephropathy patient. (16702803)
2006
14
Superinfection of perinephric abscess by Stenotrophomonas maltophilia in a tetraplegic patient. (15672091)
2005
15
Passive seeding in metanephric adenoma: a review of pseudometastatic lesions in perinephric lymph nodes. (16196523)
2005
16
Perinephric angiomyolipoma: a unique development pattern surrounding the kidney. (15828960)
2005
17
Left perinephric abscess associated with nephrolithiasis and bladder calculi in a bitch. (15144002)
2004
18
Perinephric urinoma secondary to neurogenic bladder with vesicoureteral reflux: report of an adult case. (14678187)
2004
19
A model for perinephric fluid accumulation in uremic rats with toxic nephrosis. (14615063)
2003
20
Perinephric cystic mesoblastic nephroma complicated by hepatic metastases: a case report. (12389112)
2002
21
In utero perinephric urinoma and urinary ascites with posterior urethral valves: a paradoxical pop-off valve? (11696793)
2001
22
Perinephric hematoma and massive gastrointestinal hemorrhage (GIB) complicating polyarteritis nodosa (PAN). (10843248)
2000
23
Bilateral xanthogranulomatous perinephritis without renal parenchymal involvement. (10879698)
2000
24
Acute ureterolithiasis: nonenhanced helical CT findings of perinephric edema for prediction of degree of ureteral obstruction. (10580936)
1999
25
Perinephric urinoma secondary to neurogenic bladder in myelodysplasia. (7815619)
1995
26
Effects of endothelin upon blood pressure in normotensive rabbits and in perinephritis hypertension. (1325511)
1992
27
Klebsiella pneumoniae urinary tract infection complicated by endophthalmitis, perinephric abscess, and ecthyma gangrenosum. (2052978)
1991
28
Xanthogranulomatous pyelonephritis, perinephric type--a case report. (1942997)
1991
29
Bilateral excision of perinephric fat and fascia (Gerota's fasciectomy) in the treatment of intractable chyluria. (1942297)
1991
30
Noradrenaline sensitivity and calcium fluxes in arteries from rabbits with perinephritis hypertension. (2208798)
1990
31
Successful treatment for perinephric abscess with recombinant human granulocyte colony-stimulating factor following nephrectomy in a patient of myelodysplastic syndrome: a case report. (1698422)
1990
32
Platelet cytosolic free calcium before and after antihypertensive treatment in perinephritis hypertension of the rabbit. (2571432)
1989
33
45Ca uptake and the actions of Bay K 8644 on aortic strips from rabbits with perinephritis hypertension. (2448370)
1987
34
Cardiac and lymphocyte beta-adrenoceptors in perinephritis hypertension in the rabbit. (2425174)
1986
35
Studies on alpha 2-adrenoceptors in rabbits with perinephritis hypertension. (2870119)
1986
36
Xanthogranulomatous perinephritis: unusual cause of renal vein and vena caval thrombosis. (3984116)
1985
37
Renal carcinoma with staghorn calculus, perinephric abscess, and xanthogranulomatous pyelonephritis in same kidney. Subcutaneous abscess of thigh as initial presentation. (6868240)
1983
38
Role of the renin-angiotensin system in dogs with perinephritis hypertension. (967886)
1976
39
Colonic changes secondary to left perinephritis: new observations. (4828982)
1974
40
Increased serum cholesterol and non-esterified fatty acid levels in rats with constrictive perinephritis and maintained on normal diet. (4841653)
1974
41
Renal cortical abscess, perinephritis and perinephric abscess in diabetes. (4713176)
1973
42
Hypertension associated with traumatic perinephritis. (13988619)
1963
43
Periarteritis nodosa complicated by spontaneous perinephric hematoma; roentgenographic findings in three cases and a review of the literature. (13731554)
1960
44
Perinephritis plastica. (13216975)
1954
45
II. Establishment of hypertension in rats; hypertension caused by perinephritis. (13002117)
1952
46
Perinephritis with and without operation. (20247050)
1946
47
Perinephritis and perirenal abscess. (20279545)
1946
48
Perinephritis. (18742659)
1933
49
Perinephritis - Suppurative and Nonsuppurative. (18742440)
1933
50
Acute Non-Suppurative Perinephritis. (20760378)
1902

Genetic Variations for Perinephritis

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Expression for genes affiliated with Perinephritis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Perinephritis

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Pathways for genes affiliated with Perinephritis

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37NCBI BioSystems Database, 29KEGG
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Pathways related to Perinephritis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
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9.4IL4I1, MDM2

Compounds for genes affiliated with Perinephritis

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44Novoseek, 11DrugBank, 49PharmGKB, 24HMDB, 59Tocris Bioscience
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Compounds related to Perinephritis according to GeneCards/GeneDecks:

(show all 20)
idCompoundScoreTop Affiliating Genes
12-chlorodeoxyadenosine449.8MDM2, CSF3
2ifosfamide44 1110.8CSF3, MDM2
3fludarabine44 1110.7CSF3, MDM2
4hydroxyethyl starch449.7ALB, CSF3
5daunorubicin44 49 1111.7CSF3, MDM2
6mycophenolate mofetil44 49 1111.7ALB, CSF3
7vinblastine44 49 1111.7MDM2, CSF3
8carboplatin44 49 1111.6CSF3, MDM2
9gefitinib44 49 1111.6MDM2, ALB
10zidovudine44 1110.4ALB, CSF3
11mitomycin c449.4CSF3, MDM2
12irinotecan44 49 1111.3ALB, MDM2, CSF3
13imatinib44 49 1111.3CSF3, MDM2, ALB
14melphalan44 1110.2CSF3, MDM2, IL4I1
15vincristine44 49 1111.2MDM2, CSF3
16iron44 249.9ALB, KRT7, MDM2
17testosterone44 59 11 2411.7ALB, KRT7, MDM2
18vegf448.7KRT7, MDM2, CSF3
19methotrexate44 49 1110.5ALB, KRT7, MDM2, CSF3
20tyrosine448.3KRT7, IL4I1, MDM2, CSF3

GO Terms for genes affiliated with Perinephritis

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16Gene Ontology
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Molecular functions related to Perinephritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1enzyme bindingGO:0198999.0ALB, MDM2, CSF3

Products for genes affiliated with Perinephritis

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Sources for Perinephritis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet