MCID: PRN007
MIFTS: 31

Perinephritis

Categories: Nephrological diseases

Aliases & Classifications for Perinephritis

MalaCards integrated aliases for Perinephritis:

Name: Perinephritis 12 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:2982
MeSH 42 D010501
SNOMED-CT 64 111404004
UMLS 69 C0031065

Summaries for Perinephritis

MalaCards based summary : Perinephritis is related to pyelonephritis and xanthogranulomatous pyelonephritis. An important gene associated with Perinephritis is REN (Renin), and among its related pathways/superpathways are Peptide ligand-binding receptors and Calcium signaling pathway. Affiliated tissues include kidney, colon and smooth muscle, and related phenotypes are homeostasis/metabolism and muscle

Related Diseases for Perinephritis

Diseases related to Perinephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 96)
id Related Disease Score Top Affiliating Genes
1 pyelonephritis 30.2 EDN1 REN
2 xanthogranulomatous pyelonephritis 28.6 ADRB2 EDN1 EDNRA EDNRB REN
3 tempi syndrome 11.6
4 uterine inflammatory disease 10.5 EDN1 REN
5 hepatic infarction 10.5 EDN1 REN
6 hyperekplexia 2, autosomal recessive 10.4 EDN1 EDNRA
7 wernicke-korsakoff syndrome 10.4 MGAM REN
8 chylocele of tunica vaginalis 10.4 EDN1 REN
9 eustachian tube disease 10.4 EDN1 REN
10 myopia 10.4 EDN1 REN
11 isolated scaphocephaly 10.4 EDNRA EDNRB
12 traumatic glaucoma 10.4 EDN1 EDNRA
13 lethal midline granuloma 10.3 EDNRA EDNRB
14 aortopulmonary window 10.3 ADRB2 EDN1
15 herpetic whitlow 10.3 EDNRA EDNRB
16 broad ligament malignant neoplasm 10.3 EDN1 REN
17 lymphadenitis 10.3 EDN1 REN
18 segmental odontomaxillary dysplasia 10.3 EDNRA EDNRB
19 capillary hemangioma 10.3 EDN1 REN
20 male reproductive system disease 10.3 MGAM REN
21 uterine corpus adenocarcinofibroma 10.3 MGAM REN
22 silver-russell syndrome due to 11p15 microduplication 10.3 EDN1 REN
23 nephrotic syndrome, idiopathic, steroid-resistant 10.3 EDN1 EDNRA
24 blackwater fever 10.3 EDN1 EDNRB
25 paranasal sinus sarcoma 10.2 EDN1 REN
26 acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22) 10.2 ADRB2 EDN1
27 astrakhan spotted fever 10.2 MGAM REN
28 indeterminate leprosy 10.2 EDN1 HTR7
29 hematocele of tunica vaginalis testis 10.1 EDN1 HTR7
30 diabetic encephalopathy 10.1 EDN1 REN
31 periampullary adenoma 10.1 EDN1 REN
32 inflammatory diarrhea 10.1 HTR7 MGAM
33 skull base neoplasm 10.0 EDN1 EDNRA
34 cervix uteri carcinoma in situ 10.0 EDNRA EDNRB REN
35 bubonic plague 9.9 EDN1 EDNRA
36 esophageal leukoplakia 9.9 EDN1 EDNRA EDNRB
37 polymicrogyria, bilateral frontoparietal 9.9 ADRB2 EDN1 MGAM
38 hydronephrosis 9.8
39 adenoma 9.8
40 polyarteritis nodosa 9.8
41 calcinosis 9.8 EDN1 REN
42 craniosynostosis 9.7 ADRB2 EDN1 EDNRA REN
43 hepatitis 9.7
44 renal oncocytoma 9.7
45 lymphoma 9.7
46 neurogenic bladder 9.7
47 splenic abscess 9.7
48 liposarcoma 9.7
49 ureteral obstruction 9.7
50 lymphangiomatosis 9.7

Graphical network of the top 20 diseases related to Perinephritis:



Diseases related to Perinephritis

Symptoms & Phenotypes for Perinephritis

MGI Mouse Phenotypes related to Perinephritis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.7 ADRB2 EDN1 EDNRA EDNRB HTR7 MGAM
2 muscle MP:0005369 9.35 ADRB2 EDN1 EDNRA EDNRB REN
3 nervous system MP:0003631 9.1 ADRB2 EDN1 EDNRA EDNRB HTR7 REN

Drugs & Therapeutics for Perinephritis

Search Clinical Trials , NIH Clinical Center for Perinephritis

Cochrane evidence based reviews: perinephritis

Genetic Tests for Perinephritis

Anatomical Context for Perinephritis

MalaCards organs/tissues related to Perinephritis:

39
Kidney, Colon, Smooth Muscle, Skeletal Muscle, B Cells, Lymph Node

Publications for Perinephritis

Articles related to Perinephritis:

(show top 50) (show all 92)
id Title Authors Year
1
High-grade transitional cell carcinoma masquerading as a xanthogranulomatous pyelonephritis and perinephric abscess. ( 28491170 )
2017
2
Basidiobolomycosis complicated by hydronephrosis and a perinephric abscess presenting as a hypertensive emergency in a 7-year-old boy. ( 28112037 )
2017
3
Diagnosis of perinephric retroperitoneal lymphangioma supported by contrast-enhanced ultrasound (CEUS). ( 27716656 )
2016
4
Renal Oncocytoma With Perinephric Fat Invasion. ( 27170678 )
2016
5
Severe Hydronephrosis and Perinephric Urinoma with Rupture of Renal Fornix Secondary to Postoperative Urinary Retention following Laparoscopic Umbilical Hernia Repair. ( 27555977 )
2016
6
Perinephric adipose tissue thickness in relation to blood pressure, plasma apelin and C-reactive protein levels in obese adolescents. ( 24896245 )
2016
7
Endometriosis in a kidney with focal xanthogranulomatous pyelonephritis and a perinephric abscess. ( 26490542 )
2015
8
Perinephric Stranding and Bulky Psoas Mimicking Pyelonephritis in a Case of Non-Hodgkin Lymphoma of Kidney. ( 25813655 )
2015
9
Spontaneous perinephric hemorrhage (Wunderlich syndrome) secondary to polyarteritis nodosa: Computed tomography and angiographic findings. ( 25378832 )
2014
10
Case report: a 37-year-old male with telangiectasias, polycythemia vera, perinephric fluid collections, and intrapulmonary shunting. ( 25143825 )
2014
11
Bilateral psoas and bilateral perinephric abscesses complicating acute pyelonephritis in pregnancy. ( 23580809 )
2013
12
Nephrogenic adenoma: a report of 3 unusual cases infiltrating into perinephric adipose tissue. ( 23426119 )
2013
13
Bilateral subcapsular and perinephric hemorrhage as the initial presentation of polyarteritis nodosa. ( 22576390 )
2012
14
Cystitis, pyelonephritis and perinephric abscess due to ureaplasma urealyticum. ( 23000853 )
2012
15
Radiology-pathology conference: primary perinephric and renal extraosseous Ewing's sarcoma. ( 22226450 )
2012
16
Perinephric extramedullary haematopoiesis in primary myelofibrosis. ( 22329535 )
2012
17
Perinephric drain - an unusual suspect of ureteral obstruction after open pyelolithotomy. ( 22482393 )
2012
18
Urgent referrals. Eczema herpeticum, pemphigus vulgaris, perinephric abscess, quinsy, necrotising fasciitis. ( 21510509 )
2011
19
Stage pT3a of renal clear cell carcinoma: do tumors with sinus fat involvement behave the same as those with perinephric fat involvement? ( 21655644 )
2011
20
Waldenstrom's macroglobulinemia presenting as a perinephric mass. ( 21944982 )
2011
21
A case of perinephric liposarcoma which recurred ten years later from the initial operation. ( 21372501 )
2011
22
Case report: Perinephric lymphangiomatosis. ( 21042452 )
2010
23
Computed tomography findings in bilateral perinephric lymphangiomatosis. ( 20842254 )
2010
24
Spontaneous perinephric haemorrhage and acute renal failure in pregnancy due to cocaine intoxication. ( 28657049 )
2010
25
Pseudosarcomatous fibroblastic/myofibroblastic proliferation in perinephric adipose tissue adjacent to renal cell carcinoma: a lesion mimicking well-differentiated liposarcoma. ( 19525929 )
2009
26
Bilateral perinephric diffuse large B-cell lymphoma and synchronous renal oncocytoma. ( 18364624 )
2008
27
Pyomyositis with hepatic and perinephric abscesses caused by Candida albicans in a diabetic nephropathy patient. ( 16702803 )
2006
28
Passive seeding in metanephric adenoma: a review of pseudometastatic lesions in perinephric lymph nodes. ( 16196523 )
2005
29
Perinephric angiomyolipoma: a unique development pattern surrounding the kidney. ( 15828960 )
2005
30
Superinfection of perinephric abscess by Stenotrophomonas maltophilia in a tetraplegic patient. ( 15672091 )
2005
31
Perinephric urinoma secondary to neurogenic bladder with vesicoureteral reflux: report of an adult case. ( 14678187 )
2004
32
Left perinephric abscess associated with nephrolithiasis and bladder calculi in a bitch. ( 15144002 )
2004
33
A model for perinephric fluid accumulation in uremic rats with toxic nephrosis. ( 14615063 )
2003
34
Perinephric cystic mesoblastic nephroma complicated by hepatic metastases: a case report. ( 12389112 )
2002
35
In utero perinephric urinoma and urinary ascites with posterior urethral valves: a paradoxical pop-off valve? ( 11696793 )
2001
36
Perinephric hematoma and massive gastrointestinal hemorrhage (GIB) complicating polyarteritis nodosa (PAN). ( 10843248 )
2000
37
Bilateral xanthogranulomatous perinephritis without renal parenchymal involvement. ( 10879698 )
2000
38
Acute ureterolithiasis: nonenhanced helical CT findings of perinephric edema for prediction of degree of ureteral obstruction. ( 10580936 )
1999
39
Perinephric urinoma secondary to neurogenic bladder in myelodysplasia. ( 7815619 )
1995
40
Image interpretation session: 1993. Spontaneous rupture of a renal adenoma with perinephric hemorrhage. ( 8128056 )
1994
41
Page kidney with constrictive perinephritis. ( 8341012 )
1993
42
Effects of endothelin upon blood pressure in normotensive rabbits and in perinephritis hypertension. ( 1325511 )
1992
43
Klebsiella pneumoniae urinary tract infection complicated by endophthalmitis, perinephric abscess, and ecthyma gangrenosum. ( 2052978 )
1991
44
Noradrenaline and endothelin-stimulated inositol phosphate formation in arterial smooth muscle from rabbits with perinephritis hypertension. ( 1794209 )
1991
45
Bilateral excision of perinephric fat and fascia (Gerota's fasciectomy) in the treatment of intractable chyluria. ( 1942297 )
1991
46
Xanthogranulomatous pyelonephritis, perinephric type--a case report. ( 1942997 )
1991
47
Successful treatment for perinephric abscess with recombinant human granulocyte colony-stimulating factor following nephrectomy in a patient of myelodysplastic syndrome: a case report. ( 1698422 )
1990
48
Noradrenaline sensitivity and calcium fluxes in arteries from rabbits with perinephritis hypertension. ( 2208798 )
1990
49
Inositol phosphate formation in arterial smooth muscle from rabbits with perinephritis hypertension. ( 1962806 )
1990
50
Splenic abscess arising by direct extension from a perinephric abscess. ( 2238290 )
1990

Variations for Perinephritis

Expression for Perinephritis

Search GEO for disease gene expression data for Perinephritis.

Pathways for Perinephritis

GO Terms for Perinephritis

Biological processes related to Perinephritis according to GeneCards Suite gene sharing:

(show all 26)
id Name GO ID Score Top Affiliating Genes
1 G-protein coupled receptor signaling pathway GO:0007186 9.85 ADRB2 EDN1 EDNRA EDNRB HTR7
2 cell surface receptor signaling pathway GO:0007166 9.79 ADRB2 EDN1 EDNRB
3 response to lipopolysaccharide GO:0032496 9.74 EDN1 EDNRB REN
4 positive regulation of cytosolic calcium ion concentration GO:0007204 9.69 EDN1 EDNRA EDNRB
5 cellular response to drug GO:0035690 9.63 EDN1 REN
6 sensory perception of pain GO:0019233 9.62 EDN1 EDNRB
7 calcium-mediated signaling GO:0019722 9.62 EDN1 EDNRB
8 activation of adenylate cyclase activity GO:0007190 9.61 ADRB2 EDNRA
9 respiratory gaseous exchange GO:0007585 9.6 EDN1 EDNRA
10 branching involved in blood vessel morphogenesis GO:0001569 9.59 EDN1 EDNRA
11 regulation of sensory perception of pain GO:0051930 9.58 EDN1 EDNRB
12 glucose transport GO:0015758 9.58 EDN1 EDNRA
13 neural crest cell development GO:0014032 9.56 EDN1 EDNRA
14 smooth muscle contraction GO:0006939 9.55 EDNRA HTR7
15 regulation of pH GO:0006885 9.54 EDN1 EDNRB
16 negative regulation of cAMP biosynthetic process GO:0030818 9.52 EDN1 EDNRA
17 positive regulation of renal sodium excretion GO:0035815 9.49 EDN1 EDNRB
18 positive regulation of urine volume GO:0035810 9.48 EDN1 EDNRB
19 enteric nervous system development GO:0048484 9.43 EDNRA EDNRB
20 artery smooth muscle contraction GO:0014824 9.4 EDN1 EDNRA
21 epithelial fluid transport GO:0042045 9.37 EDN1 EDNRB
22 negative regulation of cellular protein metabolic process GO:0032269 9.32 EDN1 EDNRB
23 vein smooth muscle contraction GO:0014826 9.26 EDN1 EDNRB
24 regulation of blood pressure GO:0008217 9.26 EDN1 EDNRA EDNRB REN
25 endothelin receptor signaling pathway GO:0086100 9.16 EDNRA EDNRB
26 vasoconstriction GO:0042310 8.92 EDN1 EDNRA EDNRB HTR7

Molecular functions related to Perinephritis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 signal transducer activity GO:0004871 9.33 ADRB2 EDNRA EDNRB
2 G-protein coupled receptor activity GO:0004930 9.26 ADRB2 EDNRA EDNRB HTR7
3 endothelin receptor activity GO:0004962 8.62 EDNRA EDNRB

Sources for Perinephritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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