MCID: PRN007
MIFTS: 32

Perinephritis malady

Categories: Nephrological diseases

Aliases & Classifications for Perinephritis

Aliases & Descriptions for Perinephritis:

Name: Perinephritis 12 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:2982
MeSH 42 D010501
SNOMED-CT 64 111404004
UMLS 69 C0031065

Summaries for Perinephritis

MalaCards based summary : Perinephritis is related to pyelonephritis and xanthogranulomatous pyelonephritis. An important gene associated with Perinephritis is REN (Renin), and among its related pathways/superpathways are Peptide ligand-binding receptors and Calcium signaling pathway. Affiliated tissues include kidney, smooth muscle and colon, and related phenotypes are homeostasis/metabolism and muscle

Related Diseases for Perinephritis

Diseases related to Perinephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 86)
id Related Disease Score Top Affiliating Genes
1 pyelonephritis 30.0 EDN1 REN
2 xanthogranulomatous pyelonephritis 29.6 ADRB2 EDN1 EDNRA REN
3 tempi syndrome 11.6
4 uterine inflammatory disease 10.2 EDN1 REN
5 hepatic infarction 10.2 EDN1 REN
6 immunodeficiency, common variable, 8, with autoimmunity 10.2 EDN1 EDNRA
7 transsexualism 10.2 MGAM REN
8 eastern equine encephalitis 10.2 EDN1 REN
9 myopia 10.2 EDN1 REN
10 immunodeficiency by defective expression of hla class 1 10.2 EDNRA EDNRB
11 hemorrhoid 10.2 EDN1 REN
12 esophagus carcinoma in situ 10.2 EDNRA EDNRB
13 nervous system disease 10.1 EDNRA EDNRB
14 adult brain stem glioma 10.1 MGAM REN
15 petrositis 10.1 EDN1 REN
16 benign idiopathic neonatal seizures 10.1 EDNRA EDNRB
17 aplasia cutis congenita recessive 10.1 ADRB2 EDN1
18 lymphadenitis 10.1 EDN1 REN
19 blackwater fever 10.1 EDN1 EDNRB
20 capillary hemangioma 10.1 EDN1 REN
21 poikiloderma with neutropenia 10.1 ADRB2 EDN1
22 astroblastoma 10.1 MGAM REN
23 neuroectodermal endocrine syndrome 10.1 EDN1 EDNRA
24 indeterminate leprosy 10.1 EDN1 HTR7
25 hematocele of tunica vaginalis testis 10.1 EDN1 HTR7
26 acute posterior multifocal placoid pigment epitheliopathy 10.0 ADRB2 EDN1
27 high-grade dysplasia in patients with barrett esophagus 10.0 EDN1 REN
28 superficial mycosis 10.0 HTR7 MGAM
29 zellweger syndrome 10.0 EDN1 EDNRA EDNRB
30 indian tick typhus 10.0 MGAM REN
31 paranasal sinus sarcoma 9.9 EDN1 REN
32 critical limb ischemia 9.9 ADRB2 EDN1 EDNRA REN
33 emery-dreifuss muscular dystrophy, dominant type 9.9 ADRB2 EDN1 EDNRA REN
34 sydenham chorea 9.9 EDN1 EDNRA EDNRB REN
35 polyarteritis nodosa 9.8
36 adenoma 9.8
37 hypertension, essential 9.7 ADRB2 EDN1 EDNRA EDNRB REN
38 renal oncocytoma 9.7
39 splenic abscess 9.7
40 lymphoma 9.7
41 hydronephrosis 9.7
42 liposarcoma 9.7
43 lymphangiomatosis 9.7
44 neurogenic bladder 9.7
45 ureteral obstruction 9.7
46 hepatitis 9.7
47 pemphigus vulgaris 9.5
48 lymphangioma 9.5
49 nephrogenic adenoma 9.5
50 cystitis 9.5

Graphical network of the top 20 diseases related to Perinephritis:



Diseases related to Perinephritis

Symptoms & Phenotypes for Perinephritis

MGI Mouse Phenotypes related to Perinephritis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.7 ADRB2 EDN1 EDNRA EDNRB HTR7 MGAM
2 muscle MP:0005369 9.35 ADRB2 EDN1 EDNRA EDNRB REN
3 nervous system MP:0003631 9.1 ADRB2 EDN1 EDNRA EDNRB HTR7 REN

Drugs & Therapeutics for Perinephritis

Search Clinical Trials , NIH Clinical Center for Perinephritis

Cochrane evidence based reviews: perinephritis

Genetic Tests for Perinephritis

Anatomical Context for Perinephritis

MalaCards organs/tissues related to Perinephritis:

39
Kidney, Smooth Muscle, Colon, B Cells, Skeletal Muscle, Lymph Node

Publications for Perinephritis

Articles related to Perinephritis:

(show top 50) (show all 88)
id Title Authors Year
1
Severe Hydronephrosis and Perinephric Urinoma with Rupture of Renal Fornix Secondary to Postoperative Urinary Retention following Laparoscopic Umbilical Hernia Repair. ( 27555977 )
2016
2
Renal Oncocytoma With Perinephric Fat Invasion. ( 27170678 )
2016
3
Diagnosis of perinephric retroperitoneal lymphangioma supported by contrast-enhanced ultrasound (CEUS). ( 27716656 )
2016
4
Perinephric Stranding and Bulky Psoas Mimicking Pyelonephritis in a Case of Non-Hodgkin Lymphoma of Kidney. ( 25813655 )
2015
5
Endometriosis in a kidney with focal xanthogranulomatous pyelonephritis and a perinephric abscess. ( 26490542 )
2015
6
Case report: a 37-year-old male with telangiectasias, polycythemia vera, perinephric fluid collections, and intrapulmonary shunting. ( 25143825 )
2014
7
Spontaneous perinephric hemorrhage (Wunderlich syndrome) secondary to polyarteritis nodosa: Computed tomography and angiographic findings. ( 25378832 )
2014
8
Nephrogenic adenoma: a report of 3 unusual cases infiltrating into perinephric adipose tissue. ( 23426119 )
2013
9
Bilateral psoas and bilateral perinephric abscesses complicating acute pyelonephritis in pregnancy. ( 23580809 )
2013
10
Bilateral subcapsular and perinephric hemorrhage as the initial presentation of polyarteritis nodosa. ( 22576390 )
2012
11
Cystitis, pyelonephritis and perinephric abscess due to ureaplasma urealyticum. ( 23000853 )
2012
12
Radiology-pathology conference: primary perinephric and renal extraosseous Ewing's sarcoma. ( 22226450 )
2012
13
Perinephric extramedullary haematopoiesis in primary myelofibrosis. ( 22329535 )
2012
14
Perinephric drain - an unusual suspect of ureteral obstruction after open pyelolithotomy. ( 22482393 )
2012
15
A case of perinephric liposarcoma which recurred ten years later from the initial operation. ( 21372501 )
2011
16
Urgent referrals. Eczema herpeticum, pemphigus vulgaris, perinephric abscess, quinsy, necrotising fasciitis. ( 21510509 )
2011
17
Waldenstrom's macroglobulinemia presenting as a perinephric mass. ( 21944982 )
2011
18
Stage pT3a of renal clear cell carcinoma: do tumors with sinus fat involvement behave the same as those with perinephric fat involvement? ( 21655644 )
2011
19
Computed tomography findings in bilateral perinephric lymphangiomatosis. ( 20842254 )
2010
20
Case report: Perinephric lymphangiomatosis. ( 21042452 )
2010
21
Pseudosarcomatous fibroblastic/myofibroblastic proliferation in perinephric adipose tissue adjacent to renal cell carcinoma: a lesion mimicking well-differentiated liposarcoma. ( 19525929 )
2009
22
Bilateral perinephric diffuse large B-cell lymphoma and synchronous renal oncocytoma. ( 18364624 )
2008
23
Pyomyositis with hepatic and perinephric abscesses caused by Candida albicans in a diabetic nephropathy patient. ( 16702803 )
2006
24
Superinfection of perinephric abscess by Stenotrophomonas maltophilia in a tetraplegic patient. ( 15672091 )
2005
25
Perinephric angiomyolipoma: a unique development pattern surrounding the kidney. ( 15828960 )
2005
26
Passive seeding in metanephric adenoma: a review of pseudometastatic lesions in perinephric lymph nodes. ( 16196523 )
2005
27
Left perinephric abscess associated with nephrolithiasis and bladder calculi in a bitch. ( 15144002 )
2004
28
Perinephric urinoma secondary to neurogenic bladder with vesicoureteral reflux: report of an adult case. ( 14678187 )
2004
29
A model for perinephric fluid accumulation in uremic rats with toxic nephrosis. ( 14615063 )
2003
30
Perinephric cystic mesoblastic nephroma complicated by hepatic metastases: a case report. ( 12389112 )
2002
31
In utero perinephric urinoma and urinary ascites with posterior urethral valves: a paradoxical pop-off valve? ( 11696793 )
2001
32
Bilateral xanthogranulomatous perinephritis without renal parenchymal involvement. ( 10879698 )
2000
33
Perinephric hematoma and massive gastrointestinal hemorrhage (GIB) complicating polyarteritis nodosa (PAN). ( 10843248 )
2000
34
Acute ureterolithiasis: nonenhanced helical CT findings of perinephric edema for prediction of degree of ureteral obstruction. ( 10580936 )
1999
35
Perinephric urinoma secondary to neurogenic bladder in myelodysplasia. ( 7815619 )
1995
36
Image interpretation session: 1993. Spontaneous rupture of a renal adenoma with perinephric hemorrhage. ( 8128056 )
1994
37
Page kidney with constrictive perinephritis. ( 8341012 )
1993
38
Effects of endothelin upon blood pressure in normotensive rabbits and in perinephritis hypertension. ( 1325511 )
1992
39
Klebsiella pneumoniae urinary tract infection complicated by endophthalmitis, perinephric abscess, and ecthyma gangrenosum. ( 2052978 )
1991
40
Bilateral excision of perinephric fat and fascia (Gerota's fasciectomy) in the treatment of intractable chyluria. ( 1942297 )
1991
41
Xanthogranulomatous pyelonephritis, perinephric type--a case report. ( 1942997 )
1991
42
Noradrenaline and endothelin-stimulated inositol phosphate formation in arterial smooth muscle from rabbits with perinephritis hypertension. ( 1794209 )
1991
43
Noradrenaline sensitivity and calcium fluxes in arteries from rabbits with perinephritis hypertension. ( 2208798 )
1990
44
Successful treatment for perinephric abscess with recombinant human granulocyte colony-stimulating factor following nephrectomy in a patient of myelodysplastic syndrome: a case report. ( 1698422 )
1990
45
Inositol phosphate formation in arterial smooth muscle from rabbits with perinephritis hypertension. ( 1962806 )
1990
46
Splenic abscess arising by direct extension from a perinephric abscess. ( 2238290 )
1990
47
Skeletal muscle beta 2-adrenoreceptors and the effect of adrenergic drugs on plasma potassium in perinephritis hypertension in rabbits. ( 2541134 )
1989
48
Perinephritis hypertension in Macaca fascicularis (cynomolgus monkey): studies of the renin-angiotensin-aldosterone axis and renal hemodynamic function. ( 2677140 )
1989
49
Platelet cytosolic free calcium before and after antihypertensive treatment in perinephritis hypertension of the rabbit. ( 2571432 )
1989
50
Perinephric xanthogranulomatous pyelonephritis simulating a renal or retroperitoneal tumor on X-ray CT and angiography. ( 2587801 )
1989

Variations for Perinephritis

Expression for Perinephritis

Search GEO for disease gene expression data for Perinephritis.

Pathways for Perinephritis

GO Terms for Perinephritis

Biological processes related to Perinephritis according to GeneCards Suite gene sharing:

(show all 26)
id Name GO ID Score Top Affiliating Genes
1 G-protein coupled receptor signaling pathway GO:0007186 9.85 ADRB2 EDN1 EDNRA EDNRB HTR7
2 cell surface receptor signaling pathway GO:0007166 9.79 ADRB2 EDN1 EDNRB
3 response to lipopolysaccharide GO:0032496 9.74 EDN1 EDNRB REN
4 positive regulation of cytosolic calcium ion concentration GO:0007204 9.69 EDN1 EDNRA EDNRB
5 cellular response to drug GO:0035690 9.63 EDN1 REN
6 sensory perception of pain GO:0019233 9.62 EDN1 EDNRB
7 calcium-mediated signaling GO:0019722 9.62 EDN1 EDNRB
8 activation of adenylate cyclase activity GO:0007190 9.61 ADRB2 EDNRA
9 respiratory gaseous exchange GO:0007585 9.6 EDN1 EDNRA
10 glucose transport GO:0015758 9.59 EDN1 EDNRA
11 branching involved in blood vessel morphogenesis GO:0001569 9.58 EDN1 EDNRA
12 regulation of sensory perception of pain GO:0051930 9.58 EDN1 EDNRB
13 neural crest cell development GO:0014032 9.56 EDN1 EDNRA
14 regulation of pH GO:0006885 9.55 EDN1 EDNRB
15 smooth muscle contraction GO:0006939 9.54 EDNRA HTR7
16 negative regulation of cAMP biosynthetic process GO:0030818 9.52 EDN1 EDNRA
17 positive regulation of urine volume GO:0035810 9.49 EDN1 EDNRB
18 positive regulation of renal sodium excretion GO:0035815 9.48 EDN1 EDNRB
19 enteric nervous system development GO:0048484 9.43 EDNRA EDNRB
20 artery smooth muscle contraction GO:0014824 9.4 EDN1 EDNRA
21 epithelial fluid transport GO:0042045 9.37 EDN1 EDNRB
22 negative regulation of cellular protein metabolic process GO:0032269 9.32 EDN1 EDNRB
23 vein smooth muscle contraction GO:0014826 9.26 EDN1 EDNRB
24 regulation of blood pressure GO:0008217 9.26 EDN1 EDNRA EDNRB REN
25 endothelin receptor signaling pathway GO:0086100 9.16 EDNRA EDNRB
26 vasoconstriction GO:0042310 8.92 EDN1 EDNRA EDNRB HTR7

Molecular functions related to Perinephritis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 signal transducer activity GO:0004871 9.33 ADRB2 EDNRA EDNRB
2 G-protein coupled receptor activity GO:0004930 9.26 ADRB2 EDNRA EDNRB HTR7
3 endothelin receptor activity GO:0004962 8.62 EDNRA EDNRB

Sources for Perinephritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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