MCID: PRN007
MIFTS: 32

Perinephritis malady

Category: Nephrological diseases

Aliases & Classifications for Perinephritis

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Aliases & Descriptions for Perinephritis:

Name: Perinephritis 11 39 13 68

Classifications:



External Ids:

Disease Ontology11 DOID:2982
SNOMED-CT62 111404004
MeSH39 D010501

Summaries for Perinephritis

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MalaCards based summary: Perinephritis is related to pyelonephritis and xanthogranulomatous pyelonephritis. An important gene associated with Perinephritis is REN (Renin), and among its related pathways are EGFR Transactivation by Gastrin and Arf6 trafficking events. Affiliated tissues include kidney, colon and smooth muscle, and related mouse phenotypes are muscle and homeostasis/metabolism.

Related Diseases for Perinephritis

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Diseases related to Perinephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 86)
idRelated DiseaseScoreTop Affiliating Genes
1pyelonephritis30.0EDN1, REN
2xanthogranulomatous pyelonephritis29.6ADRB2, EDN1, EDNRA, REN
3tempi syndrome11.6
4uterine inflammatory disease10.2EDN1, REN
5hepatic infarction10.2EDN1, REN
6immunodeficiency, common variable, 8, with autoimmunity10.2EDN1, EDNRA
7transsexualism10.2MGAM, REN
8eastern equine encephalitis10.2EDN1, REN
9myopia10.2EDN1, REN
10immunodeficiency by defective expression of hla class 110.2EDNRA, EDNRB
11hemorrhoid10.2EDN1, REN
12esophagus carcinoma in situ10.2EDNRA, EDNRB
13nervous system disease10.1EDNRA, EDNRB
14adult brain stem glioma10.1MGAM, REN
15petrositis10.1EDN1, REN
16benign idiopathic neonatal seizures10.1EDNRA, EDNRB
17aplasia cutis congenita recessive10.1ADRB2, EDN1
18lymphadenitis10.1EDN1, REN
19blackwater fever10.1EDN1, EDNRB
20capillary hemangioma10.1EDN1, REN
21poikiloderma with neutropenia10.1ADRB2, EDN1
22astroblastoma10.1MGAM, REN
23neuroectodermal endocrine syndrome10.1EDN1, EDNRA
24indeterminate leprosy10.1EDN1, HTR7
25hematocele of tunica vaginalis testis10.1EDN1, HTR7
26acute posterior multifocal placoid pigment epitheliopathy10.0ADRB2, EDN1
27high-grade dysplasia in patients with barrett esophagus10.0EDN1, REN
28superficial mycosis10.0HTR7, MGAM
29zellweger syndrome10.0EDN1, EDNRA, EDNRB
30indian tick typhus10.0MGAM, REN
31paranasal sinus sarcoma9.9EDN1, REN
32critical limb ischemia9.9ADRB2, EDN1, EDNRA, REN
33emery-dreifuss muscular dystrophy, dominant type9.9ADRB2, EDN1, EDNRA, REN
34sydenham chorea9.9EDN1, EDNRA, EDNRB, REN
35adenoma9.8
36polyarteritis nodosa9.8
37hypertension, essential9.7ADRB2, EDN1, EDNRA, EDNRB, REN
38hepatitis9.7
39renal oncocytoma9.7
40lymphoma9.7
41hydronephrosis9.7
42neurogenic bladder9.7
43splenic abscess9.7
44liposarcoma9.7
45ureteral obstruction9.7
46lymphangiomatosis9.7
47hodgkin lymphoma9.5
48renal cell carcinoma9.5
49myelodysplastic syndrome9.5
50b-cell lymphomas9.5

Graphical network of the top 20 diseases related to Perinephritis:



Diseases related to perinephritis

Symptoms & Phenotypes for Perinephritis

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MGI Mouse Phenotypes related to Perinephritis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053699.1ADRB2, EDN1, EDNRA, EDNRB, REN
2MP:00053768.0ADRB2, EDN1, EDNRA, EDNRB, HTR7, MGAM
3MP:00036317.7ADRB2, EDN1, EDNRA, EDNRB, HTR7, REN

Drugs & Therapeutics for Perinephritis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Perinephritis


Cochrane evidence based reviews: perinephritis

Genetic Tests for Perinephritis

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Anatomical Context for Perinephritis

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MalaCards organs/tissues related to Perinephritis:

36
Kidney, Colon, Smooth muscle, B cells, Skeletal muscle, Lymph node

Publications for Perinephritis

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Articles related to Perinephritis:

(show top 50)    (show all 88)
idTitleAuthorsYear
1
Severe Hydronephrosis and Perinephric Urinoma with Rupture of Renal Fornix Secondary to Postoperative Urinary Retention following Laparoscopic Umbilical Hernia Repair. (27555977)
2016
2
Renal Oncocytoma With Perinephric Fat Invasion. (27170678)
2016
3
Diagnosis of perinephric retroperitoneal lymphangioma supported by contrast-enhanced ultrasound (CEUS). (27716656)
2016
4
Perinephric Stranding and Bulky Psoas Mimicking Pyelonephritis in a Case of Non-Hodgkin Lymphoma of Kidney. (25813655)
2015
5
Endometriosis in a kidney with focal xanthogranulomatous pyelonephritis and a perinephric abscess. (26490542)
2015
6
Case report: a 37-year-old male with telangiectasias, polycythemia vera, perinephric fluid collections, and intrapulmonary shunting. (25143825)
2014
7
Spontaneous perinephric hemorrhage (Wunderlich syndrome) secondary to polyarteritis nodosa: Computed tomography and angiographic findings. (25378832)
2014
8
Nephrogenic adenoma: a report of 3 unusual cases infiltrating into perinephric adipose tissue. (23426119)
2013
9
Bilateral psoas and bilateral perinephric abscesses complicating acute pyelonephritis in pregnancy. (23580809)
2013
10
Bilateral subcapsular and perinephric hemorrhage as the initial presentation of polyarteritis nodosa. (22576390)
2012
11
Cystitis, pyelonephritis and perinephric abscess due to ureaplasma urealyticum. (23000853)
2012
12
Radiology-pathology conference: primary perinephric and renal extraosseous Ewing's sarcoma. (22226450)
2012
13
Perinephric extramedullary haematopoiesis in primary myelofibrosis. (22329535)
2012
14
Perinephric drain - an unusual suspect of ureteral obstruction after open pyelolithotomy. (22482393)
2012
15
A case of perinephric liposarcoma which recurred ten years later from the initial operation. (21372501)
2011
16
Urgent referrals. Eczema herpeticum, pemphigus vulgaris, perinephric abscess, quinsy, necrotising fasciitis. (21510509)
2011
17
Waldenstrom's macroglobulinemia presenting as a perinephric mass. (21944982)
2011
18
Stage pT3a of renal clear cell carcinoma: do tumors with sinus fat involvement behave the same as those with perinephric fat involvement? (21655644)
2011
19
Computed tomography findings in bilateral perinephric lymphangiomatosis. (20842254)
2010
20
Case report: Perinephric lymphangiomatosis. (21042452)
2010
21
Pseudosarcomatous fibroblastic/myofibroblastic proliferation in perinephric adipose tissue adjacent to renal cell carcinoma: a lesion mimicking well-differentiated liposarcoma. (19525929)
2009
22
Bilateral perinephric diffuse large B-cell lymphoma and synchronous renal oncocytoma. (18364624)
2008
23
Pyomyositis with hepatic and perinephric abscesses caused by Candida albicans in a diabetic nephropathy patient. (16702803)
2006
24
Superinfection of perinephric abscess by Stenotrophomonas maltophilia in a tetraplegic patient. (15672091)
2005
25
Perinephric angiomyolipoma: a unique development pattern surrounding the kidney. (15828960)
2005
26
Passive seeding in metanephric adenoma: a review of pseudometastatic lesions in perinephric lymph nodes. (16196523)
2005
27
Left perinephric abscess associated with nephrolithiasis and bladder calculi in a bitch. (15144002)
2004
28
Perinephric urinoma secondary to neurogenic bladder with vesicoureteral reflux: report of an adult case. (14678187)
2004
29
A model for perinephric fluid accumulation in uremic rats with toxic nephrosis. (14615063)
2003
30
Perinephric cystic mesoblastic nephroma complicated by hepatic metastases: a case report. (12389112)
2002
31
In utero perinephric urinoma and urinary ascites with posterior urethral valves: a paradoxical pop-off valve? (11696793)
2001
32
Bilateral xanthogranulomatous perinephritis without renal parenchymal involvement. (10879698)
2000
33
Perinephric hematoma and massive gastrointestinal hemorrhage (GIB) complicating polyarteritis nodosa (PAN). (10843248)
2000
34
Acute ureterolithiasis: nonenhanced helical CT findings of perinephric edema for prediction of degree of ureteral obstruction. (10580936)
1999
35
Perinephric urinoma secondary to neurogenic bladder in myelodysplasia. (7815619)
1995
36
Image interpretation session: 1993. Spontaneous rupture of a renal adenoma with perinephric hemorrhage. (8128056)
1994
37
Page kidney with constrictive perinephritis. (8341012)
1993
38
Effects of endothelin upon blood pressure in normotensive rabbits and in perinephritis hypertension. (1325511)
1992
39
Klebsiella pneumoniae urinary tract infection complicated by endophthalmitis, perinephric abscess, and ecthyma gangrenosum. (2052978)
1991
40
Bilateral excision of perinephric fat and fascia (Gerota's fasciectomy) in the treatment of intractable chyluria. (1942297)
1991
41
Xanthogranulomatous pyelonephritis, perinephric type--a case report. (1942997)
1991
42
Noradrenaline and endothelin-stimulated inositol phosphate formation in arterial smooth muscle from rabbits with perinephritis hypertension. (1794209)
1991
43
Noradrenaline sensitivity and calcium fluxes in arteries from rabbits with perinephritis hypertension. (2208798)
1990
44
Successful treatment for perinephric abscess with recombinant human granulocyte colony-stimulating factor following nephrectomy in a patient of myelodysplastic syndrome: a case report. (1698422)
1990
45
Inositol phosphate formation in arterial smooth muscle from rabbits with perinephritis hypertension. (1962806)
1990
46
Splenic abscess arising by direct extension from a perinephric abscess. (2238290)
1990
47
Skeletal muscle beta 2-adrenoreceptors and the effect of adrenergic drugs on plasma potassium in perinephritis hypertension in rabbits. (2541134)
1989
48
Perinephritis hypertension in Macaca fascicularis (cynomolgus monkey): studies of the renin-angiotensin-aldosterone axis and renal hemodynamic function. (2677140)
1989
49
Platelet cytosolic free calcium before and after antihypertensive treatment in perinephritis hypertension of the rabbit. (2571432)
1989
50
Perinephric xanthogranulomatous pyelonephritis simulating a renal or retroperitoneal tumor on X-ray CT and angiography. (2587801)
1989

Variations for Perinephritis

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Expression for genes affiliated with Perinephritis

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Search GEO for disease gene expression data for Perinephritis.

Pathways for genes affiliated with Perinephritis

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GO Terms for genes affiliated with Perinephritis

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Biological processes related to Perinephritis according to GeneCards Suite gene sharing:

(show all 26)
idNameGO IDScoreTop Affiliating Genes
1activation of adenylate cyclase activityGO:000719010.4ADRB2, EDNRA
2cellular response to drugGO:003569010.4EDN1, REN
3artery smooth muscle contractionGO:001482410.4EDN1, EDNRA
4branching involved in blood vessel morphogenesisGO:000156910.4EDN1, EDNRA
5glucose transportGO:001575810.3EDN1, EDNRA
6negative regulation of cAMP biosynthetic processGO:003081810.3EDN1, EDNRA
7endothelin receptor signaling pathwayGO:008610010.3EDNRA, EDNRB
8neural crest cell developmentGO:001403210.3EDN1, EDNRA
9enteric nervous system developmentGO:004848410.3EDNRA, EDNRB
10respiratory gaseous exchangeGO:000758510.3EDN1, EDNRA
11calcium-mediated signalingGO:001972210.2EDN1, EDNRB
12epithelial fluid transportGO:004204510.2EDN1, EDNRB
13negative regulation of cellular protein metabolic processGO:003226910.2EDN1, EDNRB
14positive regulation of renal sodium excretionGO:003581510.1EDN1, EDNRB
15positive regulation of urine volumeGO:003581010.1EDN1, EDNRB
16regulation of pHGO:000688510.1EDN1, EDNRB
17regulation of sensory perception of painGO:005193010.1EDN1, EDNRB
18sensory perception of painGO:00192339.9EDN1, EDNRB
19smooth muscle contractionGO:00069399.8EDNRA, HTR7
20cell surface receptor signaling pathwayGO:00071669.8ADRB2, EDN1, EDNRB
21positive regulation of cytosolic calcium ion concentrationGO:00072049.8EDN1, EDNRA, EDNRB
22response to lipopolysaccharideGO:00324969.7EDN1, EDNRB, REN
23vein smooth muscle contractionGO:00148269.5EDN1, EDNRB
24regulation of blood pressureGO:00082179.4EDN1, EDNRA, EDNRB, REN
25G-protein coupled receptor signaling pathwayGO:00071868.8ADRB2, EDN1, EDNRA, EDNRB, HTR7
26vasoconstrictionGO:00423108.6EDN1, EDNRA, EDNRB, HTR7

Molecular functions related to Perinephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1endothelin receptor activityGO:000496210.3EDNRA, EDNRB
2G-protein coupled receptor activityGO:00049309.2ADRB2, EDNRA, EDNRB, HTR7
3signal transducer activityGO:00048719.2ADRB2, EDNRA, EDNRB

Sources for Perinephritis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet