MCID: PRN007
MIFTS: 33

Perinephritis malady

Summaries for Perinephritis

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32MalaCards
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MalaCards: Perinephritis is related to adenoma and sarcoma. An important gene associated with Perinephritis is MDM2 (MDM2 oncogene, E3 ubiquitin protein ligase), and among its related pathways is Tryptophan metabolism. The compounds 2-chlorodeoxyadenosine and ifosfamide have been mentioned in the context of this disorder. Affiliated tissues include kidney, smooth muscle and colon, and related mouse phenotype renal/urinary system.

Aliases & Classifications for Perinephritis

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8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 34MeSH
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Aliases & Descriptions:

perinephritis 8 10 60


External Ids:

Disease Ontology8 DOID:2982
SNOMED-CT56 111404004
MeSH34 D010501

Related Diseases for Perinephritis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Perinephritis:



Diseases related to perinephritis

Clinical Features for Perinephritis

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Drugs & Therapeutics for Perinephritis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Perinephritis

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Anatomical Context for Perinephritis

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32MalaCards
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MalaCards organs/tissues related to Perinephritis:

32
Kidney, Smooth muscle, Colon, Skeletal muscle, B cells, Lymph node

Animal Models for Perinephritis or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Perinephritis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.2ALB, KRT7, MDM2, CSF3

Publications for Perinephritis

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50PubMed
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Articles related to Perinephritis:

(show top 50)    (show all 81)
idTitleAuthorsYear
1
Bilateral psoas and bilateral perinephric abscesses complicating acute pyelonephritis in pregnancy. (23580809)
2013
2
Bilateral subcapsular and perinephric hemorrhage as the initial presentation of polyarteritis nodosa. (22576390)
2012
3
Perinephric drain - an unusual suspect of ureteral obstruction after open pyelolithotomy. (22482393)
2012
4
Radiology-pathology conference: primary perinephric and renal extraosseous Ewing's sarcoma. (22226450)
2012
5
Stage pT3a of renal clear cell carcinoma: do tumors with sinus fat involvement behave the same as those with perinephric fat involvement? (21655644)
2011
6
Waldenstrom's macroglobulinemia presenting as a perinephric mass. (21944982)
2011
7
A case of perinephric liposarcoma which recurred ten years later from the initial operation. (21372501)
2011
8
Case report: Perinephric lymphangiomatosis. (21042452)
2010
9
Computed tomography findings in bilateral perinephric lymphangiomatosis. (20842254)
2010
10
Pseudosarcomatous fibroblastic/myofibroblastic proliferation in perinephric adipose tissue adjacent to renal cell carcinoma: a lesion mimicking well-differentiated liposarcoma. (19525929)
2009
11
Pyomyositis with hepatic and perinephric abscesses caused by Candida albicans in a diabetic nephropathy patient. (16702803)
2006
12
Superinfection of perinephric abscess by Stenotrophomonas maltophilia in a tetraplegic patient. (15672091)
2005
13
Passive seeding in metanephric adenoma: a review of pseudometastatic lesions in perinephric lymph nodes. (16196523)
2005
14
Perinephric angiomyolipoma: a unique development pattern surrounding the kidney. (15828960)
2005
15
Perinephric hematoma and massive gastrointestinal hemorrhage (GIB) complicating polyarteritis nodosa (PAN). (10843248)
2000
16
Image interpretation session: 1993. Spontaneous rupture of a renal adenoma with perinephric hemorrhage. (8128056)
1994
17
Page kidney with constrictive perinephritis. (8341012)
1993
18
Noradrenaline and endothelin-stimulated inositol phosphate formation in arterial smooth muscle from rabbits with perinephritis hypertension. (1794209)
1991
19
Klebsiella pneumoniae urinary tract infection complicated by endophthalmitis, perinephric abscess, and ecthyma gangrenosum. (2052978)
1991
20
Xanthogranulomatous pyelonephritis, perinephric type--a case report. (1942997)
1991
21
Noradrenaline sensitivity and calcium fluxes in arteries from rabbits with perinephritis hypertension. (2208798)
1990
22
Successful treatment for perinephric abscess with recombinant human granulocyte colony-stimulating factor following nephrectomy in a patient of myelodysplastic syndrome: a case report. (1698422)
1990
23
Splenic abscess arising by direct extension from a perinephric abscess. (2238290)
1990
24
Inositol phosphate formation in arterial smooth muscle from rabbits with perinephritis hypertension. (1962806)
1990
25
Platelet cytosolic free calcium before and after antihypertensive treatment in perinephritis hypertension of the rabbit. (2571432)
1989
26
Perinephric xanthogranulomatous pyelonephritis simulating a renal or retroperitoneal tumor on X-ray CT and angiography. (2587801)
1989
27
Perinephritis hypertension in Macaca fascicularis (cynomolgus monkey): studies of the renin-angiotensin-aldosterone axis and renal hemodynamic function. (2677140)
1989
28
Skeletal muscle beta 2-adrenoreceptors and the effect of adrenergic drugs on plasma potassium in perinephritis hypertension in rabbits. (2541134)
1989
29
Electrophysiological properties of the mesenteric artery of the rabbit with perinephritis hypertension. (3390614)
1988
30
Desensitization of vascular and platelet alpha 2-adrenoceptors in rabbits with perinephritis hypertension. (2897989)
1988
31
Perisplenitis and perinephritis in the Curtis-Fitz-Hugh syndrome. (3815024)
1987
32
Splenic abscess as complication of perinephric abscess. (3629772)
1987
33
Alterations of the glomerular beta-adrenoceptor-linked adenylate cyclase system in perinephritis hypertension. (2419695)
1986
34
Systemic and regional haemodynamic profile of captopril in conscious rabbits with bilateral cellophane perinephritis hypertension. (3912085)
1985
35
Systemic and regional hemodynamic characteristics of bilateral cellophane perinephritis hypertension in conscious rabbits. (6883748)
1983
36
Alpha adrenoceptors and autonomic mechanisms in perinephritis hypertension in the rabbit. (6317553)
1983
37
Serum angiotensin converting enzyme activity and the capacity to develop hypertention-associated arterial disease. Studies during the induction phase of one-kidney perinephritis hypertension in rabbits. (213977)
1978
38
Hemodynamic effects of an angiotensin II antagonist in rabbits with perinephritis hypertension. (866354)
1977
39
Perinephritis hypertension in monkeys. I. An increase of plasma renin activity associated with increased permeability of retinal vessels and angionecrosis. (6807)
1976
40
Cellophane perinephritis hypertension and its reversal in rabbits. Effect on plasma renin, renin substrate, and renal mass. (4358201)
1973
41
A case of perinephritis with renal artery stenosis and hypertension. (5654387)
1968
42
Renal malakoplakia with perinephric extension. (5678166)
1968
43
Perinephritis plastica. (13234106)
1955
44
Perinephritis plastica. (13216975)
1954
45
Perinephric cyst: report of case associated with ureteropelvic occlusion and congenital hydronephrosis. (13131408)
1953
46
Perinephric and renal cortical abscess due to colon bacillus without bacteriuria or pyuria. (12991005)
1952
47
Perinephritis and perinephric abscess; a study of 37 cases. (18135670)
1949
48
Latex rubber capsule for producing hypertension in rats by perinephritis. (20239439)
1947
49
Perinephritis with and without operation. (20247050)
1946
50
The pathological anatomy of cellophane perinephritis. (19970495)
1940

Genetic Variations for Perinephritis

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Expression for genes affiliated with Perinephritis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Perinephritis

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Pathways for genes affiliated with Perinephritis

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37NCBI BioSystems Database, 29KEGG
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Pathways related to Perinephritis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
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9.4IL4I1, MDM2

Compounds for genes affiliated with Perinephritis

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44Novoseek, 11DrugBank, 49PharmGKB, 24HMDB, 59Tocris Bioscience
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Compounds related to Perinephritis according to GeneCards/GeneDecks:

(show all 20)
idCompoundScoreTop Affiliating Genes
12-chlorodeoxyadenosine449.8MDM2, CSF3
2ifosfamide44 1110.8CSF3, MDM2
3fludarabine44 1110.7CSF3, MDM2
4hydroxyethyl starch449.7ALB, CSF3
5daunorubicin44 49 1111.7CSF3, MDM2
6mycophenolate mofetil44 49 1111.7ALB, CSF3
7vinblastine44 49 1111.7MDM2, CSF3
8carboplatin44 49 1111.6CSF3, MDM2
9gefitinib44 49 1111.6MDM2, ALB
10zidovudine44 1110.4ALB, CSF3
11mitomycin c449.4CSF3, MDM2
12irinotecan44 49 1111.3ALB, MDM2, CSF3
13imatinib44 49 1111.3CSF3, MDM2, ALB
14melphalan44 1110.2CSF3, MDM2, IL4I1
15vincristine44 49 1111.2MDM2, CSF3
16iron44 249.9ALB, KRT7, MDM2
17testosterone44 59 11 2411.7ALB, KRT7, MDM2
18vegf448.7KRT7, MDM2, CSF3
19methotrexate44 49 1110.5ALB, KRT7, MDM2, CSF3
20tyrosine448.3KRT7, IL4I1, MDM2, CSF3

GO Terms for genes affiliated with Perinephritis

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16Gene Ontology
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Molecular functions related to Perinephritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1enzyme bindingGO:0198999.0ALB, MDM2, CSF3

Products for genes affiliated with Perinephritis

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Sources for Perinephritis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet