PFAPA
MCID: PRD012
MIFTS: 11

Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis (PFAPA) malady

Summaries for Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis

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42NIH Rare Diseases, 32MalaCards
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NIH Rare Diseases:42 Periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis (pfapa) is a periodic disease, which is a heterogeneous group of disorders characterized by short episodes of illness that regularly recur for several years alternated with healthy periods. pfapa is characterized by high fevers lasting three to six days and recurring every 21 to 28 days, accompanied by some or all of the signs noted in its name, namely mouth sores (aphthous stomatitis), sore throat (pharyngitis), and enlarged lymph nodes (cervical adenitis). the syndrome usually occurs in children younger than five years; although it has been reported in children up to 13 years. the syndrome is sporadic and non-hereditary. the course of pfapa can be persistent for years before spontaneous, full resolution. last updated: 10/7/2013

MalaCards: Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis, also known as marshall syndrome, is related to pharyngitis and aphthous stomatitis. An important gene associated with Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis is TNF (tumor necrosis factor). Affiliated tissues include lymph node.

Aliases & Classifications for Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis

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Aliases & Descriptions:

periodic fever, aphthous stomatitis, pharyngitis and adenitis 42
marshall syndrome 42 60
pfapa 42


Related Diseases for Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis

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Diseases related to Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 18)
idRelated DiseaseScoreTop Affiliating Genes
1pharyngitis11.1
2aphthous stomatitis11.1
3stomatitis11.1
4adult syndrome10.6
5marshall syndrome10.6
6cervical adenitis10.4
7cervicitis10.4
8marshall syndrome with periodic fever10.2
9cutis laxa10.0
10stickler syndrome10.0
11congenital syphilis10.0
12syphilis10.0
13proliferative glomerulonephritis9.9
14autoimmune hepatitis9.9
15tonsillitis9.9
16kawasaki disease9.9
17conjunctivitis9.9
18encephalitis9.9

Graphical network of diseases related to Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis:



Diseases related to periodic fever, aphthous stomatitis, pharyngitis and adenitis

Clinical Features for Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis

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Drugs & Therapeutics for Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Genetic Tests for Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis

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Anatomical Context for Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis

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MalaCards organs/tissues related to Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis:

32
Lymph node

Animal Models for Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis or affiliated genes

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Publications for Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis

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Genetic Variations for Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis

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Expression for genes affiliated with Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis

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Pathways for genes affiliated with Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis

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Compounds for genes affiliated with Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis

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GO Terms for genes affiliated with Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis

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Products for genes affiliated with Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis

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  • Antibodies
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Sources for Periodic Fever, Aphthous Stomatitis, Pharyngitis and Adenitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
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36MGI
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40NDF-RT
43NINDS
44Novoseek
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47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
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