MCID: PRD002
MIFTS: 23

Periodic Limb Movement Disorder malady

Summaries for Periodic Limb Movement Disorder

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8Disease Ontology, 63Wikipedia, 32MalaCards
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Wikipedia:63 Periodic limb movement disorder (PLMD), previously known as nocturnal myoclonus, is a sleep disorder... more...

MalaCards: Periodic Limb Movement Disorder, also known as nocturnal myoclonus, is related to restless legs syndrome and sleep disorder. An important gene associated with Periodic Limb Movement Disorder is DRD2 (dopamine receptor D2). Affiliated tissues include testes, brain and globus pallidus.

Disease Ontology:8 A sleep disorder that involves involuntary limb movement during sleep.

Aliases & Classifications for Periodic Limb Movement Disorder

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8Disease Ontology, 44Novoseek, 27ICD9CM, 56SNOMED-CT, 60UMLS, 34MeSH
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Aliases & Descriptions:

periodic limb movement disorder 8 44
nocturnal myoclonus 8


External Ids:

Disease Ontology8 DOID:9207
ICD9CM27 327.51
SNOMED-CT56 418763003
MeSH34 D020189

Related Diseases for Periodic Limb Movement Disorder

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Periodic Limb Movement Disorder via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 12)
idRelated DiseaseScoreTop Affiliating Genes
1restless legs syndrome10.9
2sleep disorder10.9
3attention deficit hyperactivity disorder10.3
4adult syndrome10.3
5parkinson's disease10.2
6narcolepsy10.2
7conduct disorder10.2
8brain disease10.2
9migraine10.2
10mood disorder10.2
11movement disease10.2
12image syndrome10.1

Graphical network of diseases related to Periodic Limb Movement Disorder:



Diseases related to periodic limb movement disorder

Clinical Features for Periodic Limb Movement Disorder

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Drugs & Therapeutics for Periodic Limb Movement Disorder

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Periodic Limb Movement Disorder

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Anatomical Context for Periodic Limb Movement Disorder

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32MalaCards
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MalaCards organs/tissues related to Periodic Limb Movement Disorder:

32
Testes, Brain, Globus pallidus

Animal Models for Periodic Limb Movement Disorder or affiliated genes

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Publications for Periodic Limb Movement Disorder

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50PubMed
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Articles related to Periodic Limb Movement Disorder:

(show top 50)    (show all 70)
idTitleAuthorsYear
1
The validity of the PAM-RL device for evaluating periodic limb movements in sleep and an investigation on night-to-night variability of periodic limb movements during sleep in patients with restless legs syndrome or periodic limb movement disorder using this system. (24269130)
2014
2
Night-to-night variability of periodic leg movements during sleep in restless legs syndrome and periodic limb movement disorder: comparison between the periodicity index and the PLMS index. (23068780)
2013
3
Bilateral globus pallidus internus deep brain stimulation in Parkinson's disease with periodic limb movement disorder. (23344876)
2013
4
Treatment of childhood-onset restless legs syndrome and periodic limb movement disorder using intravenous iron sucrose. (23993871)
2013
5
Sleep-disordered breathing and periodic limb movements in narcolepsy with cataplexy: a systematic analysis of 35 consecutive patients. (23689193)
2013
6
Update to the AASM Clinical Practice Guideline: "The treatment of restless legs syndrome and periodic limb movement disorder in adults-an update for 2012: practice parameters with an evidence-based systematic review and meta-analyses". (22851800)
2012
7
Restless leg syndrome, periodic limb movements, febrile seizures and Attention deficit hyperactivity disorder in an Indian family. (22412272)
2012
8
The treatment of restless legs syndrome and periodic limb movement disorder in adults-an update for 2012: practice parameters with an evidence-based systematic review and meta-analyses: an American Academy of Sleep Medicine Clinical Practice Guideline. (22851801)
2012
9
Clinical Inquiry. What drugs are effective for periodic limb movement disorder? (22577635)
2012
10
Impaired driving simulation in patients with Periodic Limb Movement Disorder and patients with Obstructive Sleep Apnea Syndrome. (22353445)
2012
11
L-Dopa improves Restless Legs Syndrome and periodic limb movements in sleep but not Attention-Deficit-Hyperactivity Disorder in a double-blind trial in children. (21463967)
2011
12
Restless legs syndrome, periodic leg movements, and periodic limb movement disorder in children. (21600344)
2011
13
Pediatric periodic limb movement disorder: sleep symptom and polysomnographic correlates compared to obstructive sleep apnea. (22171198)
2011
14
Restless legs syndrome and periodic limb movements disorder in the pediatric population. (20859209)
2010
15
Parents of children with periodic limb movement disorder versus sleep-disordered breathing report greater daytime mood and behavior difficulties in their child: the importance of using ICSD-2nd Edition criteria to define a PLMD study group. (19568964)
2009
16
Pediatric restless legs syndrome and periodic limb movement disorder: parent-child pairs. (19332386)
2009
17
Restless legs syndrome and periodic limb movement disorder in children and adolescents. (18555195)
2008
18
Periodic limb movements in sleep and periodic limb movement disorder. (17235435)
2007
19
Periodic leg movements in sleep and periodic limb movement disorder: prevalence, clinical significance and treatment. (16762807)
2006
20
Selected sleep disorders: restless legs syndrome and periodic limb movement disorder, sleep apnea syndrome, and narcolepsy. (17118276)
2006
21
Periodic limb movement disorder: an unusual mechanism of twiddling and potential benefit from cardiac resynchronization therapy. (15733189)
2005
22
SLEEP year in review 2003--insomnia, sleep in psychiatric disorders, periodic limb movement disorder/restless legs syndrome, sleep in medical disorders. (15532215)
2004
23
Restless legs syndrome and periodic limb movement disorder in the elderly. (15172211)
2004
24
An update on the dopaminergic treatment of restless legs syndrome and periodic limb movement disorder. (15164915)
2004
25
Activity patterns of leg muscles in periodic limb movement disorder. (14742617)
2004
26
The restless legs syndrome and periodic limb movement disorder: a review of management. (15449218)
2004
27
Cognitive and behavioral anomalies among insomnia patients with mixed restless legs and periodic limb movement disorder. (15600136)
2003
28
Periodic limb movement disorder of sleep in children. (12603789)
2003
29
The KickStrip: a novel testing device for periodic limb movement disorder. (12841376)
2003
30
Subjective sleep quality and suggested immobilization test in restless leg syndrome and periodic limb movement disorder. (12047601)
2002
31
Restless legs syndrome and periodic limb movement disorder. (12587366)
2002
32
On "Misinterpretation of sleep-breathing disorder by periodic limb movement disorder" (Sleep Breath 2001;5:131-138). (12244494)
2002
33
Exogenous melatonin in periodic limb movement disorder: an open clinical trial and a hypothesis. (11247054)
2001
34
Misinterpretation of sleep-breathing disorder by periodic limb movement disorder. (11868152)
2001
35
Sleep laboratory studies in periodic limb movement disorder (PLMD) patients as compared with normals and acute effects of ropinirole. (12404588)
2001
36
Valproate for sleep consolidation in periodic limb movement disorder. (11001243)
2000
37
An FDOPA PET study in patients with periodic limb movement disorder and restless legs syndrome. (10668725)
2000
38
Bupropion SR reduces periodic limb movements associated with arousals from sleep in depressed patients with periodic limb movement disorder. (11105739)
2000
39
Practice parameters for the treatment of restless legs syndrome and periodic limb movement disorder. An American Academy of Sleep Medicine Report. Standards of Practice Committee of the American Academy of Sleep Medicine. (10566915)
1999
40
Secondary periodic limb movement disorder and restless legs syndrome. (15310483)
1999
41
Moderate to severe periodic limb movement disorder in childhood and adolescence. (10341379)
1999
42
The treatment of restless legs syndrome and periodic limb movement disorder. An American Academy of Sleep Medicine Review. (10566916)
1999
43
Bupropion, periodic limb movement disorder, and ADHD. (10361776)
1999
44
Periodic limb movement disorder and restless legs syndrome in children with attention-deficit hyperactivity disorder. (9881529)
1998
45
Periodic limb movement disorder in neuroleptic-induced akathisia. (9642972)
1997
46
Comparison of cognitive-behavioral therapy and clonazepam for treating periodic limb movement disorder. (8843536)
1996
47
The symptomatology of periodic limb movement disorder. (9122564)
1996
48
Relationship of nasal continuous positive airway pressure to periodic limb movement disorder in a patient without sleep apnea. (8486056)
1993
49
The Babinski response and periodic limb movement disorder. (1627987)
1992
50
Periodic limb movement disorder is associated with normal motor conduction latencies when studied by central magnetic stimulation--successful use of a new technique. (1519005)
1992

Genetic Variations for Periodic Limb Movement Disorder

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Expression for genes affiliated with Periodic Limb Movement Disorder

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Periodic Limb Movement Disorder

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Pathways for genes affiliated with Periodic Limb Movement Disorder

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Compounds for genes affiliated with Periodic Limb Movement Disorder

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GO Terms for genes affiliated with Periodic Limb Movement Disorder

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Products for genes affiliated with Periodic Limb Movement Disorder

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Periodic Limb Movement Disorder

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet