MCID: PRD002
MIFTS: 24

Periodic Limb Movement Disorder malady

Mental diseases category
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Summaries for Periodic Limb Movement Disorder

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Sources:
8Disease Ontology, 65Wikipedia, 33MalaCards
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Wikipedia:65 Periodic limb movement disorder (PLMD), previously known as nocturnal myoclonus, is a sleep disorder... more...

MalaCards: Periodic Limb Movement Disorder, also known as nocturnal myoclonus, is related to restless legs syndrome and sleep apnea. An important gene associated with Periodic Limb Movement Disorder is DRD2 (dopamine receptor D2). Affiliated tissues include testes, brain and globus pallidus.

Disease Ontology:8 A sleep disorder that involves involuntary limb movement during sleep.

Aliases & Classifications for Periodic Limb Movement Disorder

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Sources:
8Disease Ontology, 45Novoseek, 62UMLS, 27ICD9CM, 58SNOMED-CT, 35MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Mental diseases


Aliases & Descriptions:

periodic limb movement disorder 8 45
nocturnal myoclonus 8


External Ids:

Disease Ontology8 DOID:9207
ICD9CM27 327.51
SNOMED-CT58 418763003
MeSH35 D020189

Related Diseases for Periodic Limb Movement Disorder

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Periodic Limb Movement Disorder via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 11)
idRelated DiseaseScoreTop Affiliating Genes
1restless legs syndrome11.0
2sleep apnea10.6
3insomnia10.5
4obstructive sleep apnea10.4
5myoclonus10.4
6attention deficit hyperactivity disorder10.4
7sleep disorder10.4
8narcolepsy10.2
9parkinson's disease10.2
10migraine10.2
11hypersomnia10.1

Graphical network of diseases related to Periodic Limb Movement Disorder:



Diseases related to periodic limb movement disorder

Symptoms for Periodic Limb Movement Disorder

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Drugs & Therapeutics for Periodic Limb Movement Disorder

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Sources:
42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Drug clinical trials:

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Genetic Tests for Periodic Limb Movement Disorder

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Anatomical Context for Periodic Limb Movement Disorder

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33MalaCards
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MalaCards organs/tissues related to Periodic Limb Movement Disorder:

33
Testes, Brain, Globus pallidus

Animal Models for Periodic Limb Movement Disorder or affiliated genes

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Publications for Periodic Limb Movement Disorder

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52PubMed
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Articles related to Periodic Limb Movement Disorder:

(show top 50)    (show all 65)
idTitleAuthorsYear
1
Migraine and periodic limb movement disorders in sleep in children: a preliminary case-control study. (23815623)
2013
2
Night-to-night variability of periodic leg movements during sleep in restless legs syndrome and periodic limb movement disorder: comparison between the periodicity index and the PLMS index. (23068780)
2013
3
Bilateral globus pallidus internus deep brain stimulation in Parkinson's disease with periodic limb movement disorder. (23344876)
2013
4
Treatment of childhood-onset restless legs syndrome and periodic limb movement disorder using intravenous iron sucrose. (23993871)
2013
5
Update to the AASM Clinical Practice Guideline: "The treatment of restless legs syndrome and periodic limb movement disorder in adults-an update for 2012: practice parameters with an evidence-based systematic review and meta-analyses". (22851800)
2012
6
All the wrong moves: a clinical review of restless legs syndrome, periodic limb movements of sleep and wake, and periodic limb movement disorder. (20488295)
2010
7
Restless legs syndrome and periodic limb movements disorder in the pediatric population. (20859209)
2010
8
Ropinirole in restless legs syndrome and periodic limb movement disorder. (20421915)
2010
9
Periodic leg movements during sleep and periodic limb movement disorder in patients presenting with unexplained insomnia. (19109055)
2009
10
Parents of children with periodic limb movement disorder versus sleep-disordered breathing report greater daytime mood and behavior difficulties in their child: the importance of using ICSD-2nd Edition criteria to define a PLMD study group. (19568964)
2009
11
Pediatric restless legs syndrome and periodic limb movement disorder: parent-child pairs. (19332386)
2009
12
Restless legs syndrome and periodic limb movement disorder in children and adolescents. (18555195)
2008
13
Periodic limb movements in sleep and periodic limb movement disorder. (17235435)
2007
14
Periodic limb movement disorder in children. (16798596)
2006
15
Periodic leg movements in sleep and periodic limb movement disorder: prevalence, clinical significance and treatment. (16762807)
2006
16
Selected sleep disorders: restless legs syndrome and periodic limb movement disorder, sleep apnea syndrome, and narcolepsy. (17118276)
2006
17
Periodic limb movement disorder: an unusual mechanism of twiddling and potential benefit from cardiac resynchronization therapy. (15733189)
2005
18
Abnormal H-reflexes in periodic limb movement disorder; impact on understanding the pathophysiology of the disorder. (15589198)
2005
19
SLEEP year in review 2003--insomnia, sleep in psychiatric disorders, periodic limb movement disorder/restless legs syndrome, sleep in medical disorders. (15532215)
2004
20
Restless legs syndrome and periodic limb movement disorder in the elderly. (15172211)
2004
21
Practice parameters for the dopaminergic treatment of restless legs syndrome and periodic limb movement disorder. (15164914)
2004
22
Restless legs syndrome and periodic limb movement disorder. (15087209)
2004
23
Periodic limb movement disorder and restless legs syndrome in dialysis patients. (15663636)
2004
24
An update on the dopaminergic treatment of restless legs syndrome and periodic limb movement disorder. (15164915)
2004
25
Activity patterns of leg muscles in periodic limb movement disorder. (14742617)
2004
26
Can periodic limb movement disorder be diagnosed without polysomnography? A case-control study. (14592358)
2003
27
Different sleep characteristics in restless legs syndrome and periodic limb movement disorder. (14592346)
2003
28
Cognitive and behavioral anomalies among insomnia patients with mixed restless legs and periodic limb movement disorder. (15600136)
2003
29
Periodic limb movement disorder of sleep in children. (12603789)
2003
30
Subjective sleep quality and suggested immobilization test in restless leg syndrome and periodic limb movement disorder. (12047601)
2002
31
Prevalence of restless legs syndrome and periodic limb movement disorder in the general population. (12127170)
2002
32
EEG mapping, psychometric, and polysomnographic studies in restless legs syndrome (RLS) and periodic limb movement disorder (PLMD) patients as compared with normal controls. (14592166)
2002
33
Restless legs syndrome and periodic limb movement disorder. (12587366)
2002
34
Exogenous melatonin in periodic limb movement disorder: an open clinical trial and a hypothesis. (11247054)
2001
35
Misinterpretation of sleep-breathing disorder by periodic limb movement disorder. (11868152)
2001
36
Periodic limb movement disorder : a clinical and polysomnographic study. (11799409)
2001
37
Sleep laboratory studies in periodic limb movement disorder (PLMD) patients as compared with normals and acute effects of ropinirole. (12404588)
2001
38
Valproate for sleep consolidation in periodic limb movement disorder. (11001243)
2000
39
An FDOPA PET study in patients with periodic limb movement disorder and restless legs syndrome. (10668725)
2000
40
Bupropion SR reduces periodic limb movements associated with arousals from sleep in depressed patients with periodic limb movement disorder. (11105739)
2000
41
Practice parameters for the treatment of restless legs syndrome and periodic limb movement disorder. An American Academy of Sleep Medicine Report. Standards of Practice Committee of the American Academy of Sleep Medicine. (10566915)
1999
42
Secondary periodic limb movement disorder and restless legs syndrome. (15310483)
1999
43
Differential rates of psychopathology symptoms in periodic limb movement disorder, obstructive sleep apnea, psychophysiological insomnia, and insomnia with psychiatric disorder. (10505823)
1999
44
Moderate to severe periodic limb movement disorder in childhood and adolescence. (10341379)
1999
45
The treatment of restless legs syndrome and periodic limb movement disorder. An American Academy of Sleep Medicine Review. (10566916)
1999
46
Periodic limb movement disorder and restless legs syndrome in children with attention-deficit hyperactivity disorder. (9881529)
1998
47
Periodic limb movement disorder in neuroleptic-induced akathisia. (9642972)
1997
48
Comparison of cognitive-behavioral therapy and clonazepam for treating periodic limb movement disorder. (8843536)
1996
49
Relationship of nasal continuous positive airway pressure to periodic limb movement disorder in a patient without sleep apnea. (8486056)
1993
50
The Babinski response and periodic limb movement disorder. (1627987)
1992

Variations for Periodic Limb Movement Disorder

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Expression for genes affiliated with Periodic Limb Movement Disorder

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Sources:
2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Periodic Limb Movement Disorder

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Pathways for genes affiliated with Periodic Limb Movement Disorder

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Compounds for genes affiliated with Periodic Limb Movement Disorder

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GO Terms for genes affiliated with Periodic Limb Movement Disorder

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Products for genes affiliated with Periodic Limb Movement Disorder

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  • Antibodies
  • Proteins
  • Lysates
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Sources for Periodic Limb Movement Disorder

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet