MCID: PRD002
MIFTS: 35

Periodic Limb Movement Disorder malady

Mental diseases category

Aliases & Classifications for Periodic Limb Movement Disorder

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Sources:
10Disease Ontology, 47Novoseek, 12DISEASES, 65UMLS, 36MeSH, 29ICD9CM, 59SNOMED-CT
See all sources

Aliases & Descriptions for Periodic Limb Movement Disorder:

Name: Periodic Limb Movement Disorder 10 47 12
Nocturnal Myoclonus Syndrome 65 36
 
Nocturnal Myoclonus 10


Classifications:



External Ids:

Disease Ontology10 DOID:9207
MeSH36 D020189
SNOMED-CT59 418763003
ICD9CM29 327.51

Summaries for Periodic Limb Movement Disorder

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Wikipedia:68 Periodic limb movement disorder (PLMD), previously known as nocturnal myoclonus, is a sleep disorder... more...

MalaCards based summary: Periodic Limb Movement Disorder, also known as nocturnal myoclonus syndrome, is related to attention deficit-hyperactivity disorder and restless legs syndrome. An important gene associated with Periodic Limb Movement Disorder is GLRA1 (Glycine Receptor, Alpha 1), and among its related pathways are Serotonin Receptor 2 and ELK-SRF/GATA4 signaling and Monoamine GPCRs. Affiliated tissues include testes, globus pallidus and brain, and related mouse phenotypes are muscle and hematopoietic system.

Disease Ontology:10 A sleep disorder that involves involuntary limb movement during sleep.

Related Diseases for Periodic Limb Movement Disorder

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Diseases related to Periodic Limb Movement Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 79)
idRelated DiseaseScoreTop Affiliating Genes
1attention deficit-hyperactivity disorder30.3CHRNA4, DRD2, HTR1A, HTR2A, HTR2C, SLC6A4
2restless legs syndrome11.0
3sleep apnea10.6
4obstructive sleep apnea10.5
5myoclonus10.4
6sleep disorder10.4
7melancholia10.3DRD2, HTR2A
8dementia10.3DRD2, HTR2A
9in situ carcinoma10.3DRD2, HTR2A
10tarlov cysts10.3DRD2, HTR2A
11subvalvular aortic stenosis10.3HTR1A, HTR2A
12spastic ectropion10.2HTR2A, SLC6A4
13spastic entropion10.2DRD2, HTR2A
14postsurgical hypothyroidism10.2HTR2A, SLC6A4
15giant cell tumor10.2HTR2A, SLC6A4
16central nervous system immature teratoma10.2DRD2, HTR1A, HTR2A
17benign peritoneal mesothelioma10.2DRD2, HTR1A, HTR2A
18deafness and myopia10.2HTR2A, HTR2C, VPS13A
19dry eye syndrome10.2DRD2, HTR1A, HTR2A
20brill-zinsser disease10.2DRD2, SLC6A4
21narcolepsy10.2
22focal epilepsy10.2
23motor neuritis10.2HTR1A, HTR2A
24ductal carcinoma in situ10.2HTR2A, KANTR
25angelucci's syndrome10.2HTR2A, KANTR
26aleukemic leukemia cutis10.2DRD2, HTR2A, SLC6A4
27trachea leiomyoma10.2DRD2, HTR2A, SLC6A4
28mixed lacrimal gland cancer10.2LCK, ZEB1
29subacute delirium10.2DRD2, HTR2A, SLC6A4
30nicotine dependence, protection against10.2CHRNA4, DRD2, HTR2A
31bacterial vaginosis10.2DRD2, HTR2A, SLC6A4
32substance dependence10.2DRD2, HTR2A, SLC6A4
33alcoholic hepatitis10.2DRD2, HTR2A, SLC6A4
34akinetopsia10.2DRD2, SLC6A4
35phosphorus metabolism disease10.2HTR1A, HTR2A, SLC6A4
36eccrine adenocarcinoma10.2DRD2, HTR2C, SLC6A4
37familial glomangioma10.2HTR1A, HTR2A, SLC6A4
38malignant renovascular hypertension10.2HTR1A, HTR2A, SLC6A4
39extrahepatic bile duct leiomyoma10.2HTR2A, KANTR
40pericardial tuberculosis10.2HTR1A, HTR2A, SLC6A4
41kleptomania10.2HTR1A, HTR2A, SLC6A4
42sideroblastic anemia10.2HTR1A, HTR2A, SLC6A4
43carotid stenosis10.1HTR2A, KANTR
44hereditary myopathy with lactic acidosis due to iscu deficiency10.1HTR1A, HTR2A, SLC6A4
45neonatal myasthenia gravis10.1HTR1A, HTR2A, SLC6A4
46chronic leukemia10.1HTR1A, HTR2A, SLC6A4
47hodgkin's lymphoma, lymphocytic-histiocytic predominance10.1HTR1A, HTR2A, SLC6A4
48cavernous hemangioma of orbit10.1DRD2, HTR1A
49germinoma10.1HTR2A, KANTR
50breast abscess10.1KANTR, PER1

Graphical network of the top 20 diseases related to Periodic Limb Movement Disorder:



Diseases related to periodic limb movement disorder

Symptoms for Periodic Limb Movement Disorder

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Drugs & Therapeutics for Periodic Limb Movement Disorder

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Drugs for Periodic Limb Movement Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 29)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
IronapprovedPhase 4, Phase 29577439-89-623925
Synonyms:
02583_FLUKA
12310_ALDRICH
12310_RIEDEL
129048-51-7
14067-02-8
161135-39-3
190454-13-8
195161-83-2
199281-22-6
209309_ALDRICH
209309_SIAL
255637_ALDRICH
266213_ALDRICH
266256_ALDRICH
267945_ALDRICH
267953_ALDRICH
26Fe
338141_ALDRICH
356808_ALDRICH
356824_ALDRICH
356832_ALDRICH
39344-71-3
3ZhP
413054_ALDRICH
443783-52-6
44890_ALDRICH
44890_FLUKA
675141-17-0
70884-35-4
73135-38-3
7439-89-6
8011-79-8
8053-60-9
AC1L2N38
ATW 230
ATW 432
Ancor B
Ancor en 80/150
Armco iron
Atomel 28
Atomel 300M200
Atomel 500M
Atomel 95
Atomiron 44MR
Atomiron 5M
Atomiron AFP 25
Atomiron AFP 5
C00023
C3518_SIAL
C3518_SIGMA
CCRIS 1580
CHEBI:18248
CID23925
Carbonyl iron
Copy Powder CS 105-175
D007501
DB01592
DSP 1000
DSP 128B
DSP 135
DSP 135C
DSP 138
Dexiron
Diseases (animal), iron overload
Diseases, iron overload
EF 1000
EF 250
EFV 200/300
EFV 250
EFV 250/400
EINECS 231-096-4
Ed-In-Sol
 
Eisen
F 60 (metal)
FE
FT 3 (element)
Fe
Fe-40
Fe1+
Feraheme
Feronate
Ferretts
Ferrlecit
Ferro-Caps
Ferro-Time
Ferrousal
Ferrovac E
Ferrum
GS 6
HF 2 (element)
HL (iron)
HQ (metal)
HS (iron)
HS 4849
HSDB 604
Hemocyte
Hierro
Hoeganaes ATW 230
Hoeganaes EH
IRMM524A_FLUKA
IRMM524B_FLUKA
IRON
Infufer
Iron
Iron (Fe)
Iron (Fe1+)
Iron ion (Fe+)
Iron ion(1+)
Iron monocation
Iron standard for AAS
Iron(1+)
Iron(1+) ion
Iron(III) nitrate solution
Iron, elemental
Iron, ion (Fe1+)
Iron, ion (Fe1+) (8CI,9CI)
LOHA
LS-3196
MolPort-003-925-001
NC 100
PZh-1M3
PZh-2
PZh1M1
PZh2M
PZh2M1
PZh2M2
PZh3
PZh3M
PZh4M
PZhO
Remko
SUY-B 2
Siderol
UNII-E1UOL152H7
Venofer
Vitedyn-Slo
Yieronia
fer
ferrous ascorbate
ferrous fumarate
ferrous gluconate
ferrous glycine sulfate
ferrous iron
ferrous succinate
ferrous sulfate
hierro
2
BenzocaineapprovedPhase 4, Phase 315361994-09-7, 94-09-72337
Synonyms:
(p-(Ethoxycarbonyl)phenylamine
06952_FLUKA
112909_ALDRICH
112909_SIAL
1333-08-0
20/20 Topical Anesthetic
23239-88-5
23239-88-5 (hydrochloride)
4 Aminobenzoic Acid Ethyl Ester
4-(Ethoxycarbonyl)aniline
4-(Ethoxycarbonyl)phenylamine
4-14-00-01129 (Beilstein Handbook Reference)
4-Aminobenzoate
4-Aminobenzoic acid
4-Aminobenzoic acid ethyl ester
4-Aminobenzoic acid, ethyl ester
4-Carbethoxyaniline
4-amino-benzoic acid ethyl ester
4-aminobenzoic acid ethyl ester
71123-91-6
94-09-7
94-09-7 (Parent)
A0271
AB00051923
AC1L1DGC
AC1Q341A
AC1Q64JE
AE-562/40377256
AI3-02081
AKOS000119763
AR-1H9065
Acetate, Benzocaine
Aethoform
Aethylium paraminobenzoicum
Alcohol Prep Pads
Allegenal-m
Alpha-caine Topical Anesthetic
Amben ethyl ester
Americaine
Anaesthan-syngala
Anaesthesin
Anaesthesinum
Anaesthin
Anbesol Jr
Anbesol Maximum Strength
Anbesol Regular Strength
Anestenka
Anestezin
Anestezin [Russian]
Anesthesin
Anesthesine
Anesthetic
Anesthone
Atopalm Oral Pain Relief
BB_SC-0019
BPBio1_001017
BRD-K75466013-001-05-2
BRN 0638434
BSPBio_000923
BSPBio_001908
Baby Anbesol
Baby Anestenka
Baby Sensigel
Baby Sensigel Night Time Formula
Baby Teething Oral Pain Reliever
Bactimicina For Sore Throat
Bencocaine Topical Anesthetic
Bensokain
Benz O Sthetic
Benzoak
Benzocaina
Benzocaina [INN-Spanish]
Benzocaine
Benzocaine (USP/INN)
Benzocaine Acetate
Benzocaine Formate
Benzocaine Hydrobromide
Benzocaine Hydrochloride
Benzocaine Methanesulfonate
Benzocaine [INN:BAN]
Benzocainum
Benzocainum [INN-Latin]
Benzodent
Benzoic acid, 4-amino-, ethyl ester
Benzoic acid, 4-amino-, ethyl ester, hydrochloride
Benzoic acid, amino-, ethyl ester
Benzoic acid, p-amino-, ethyl ester
Boil Ease
Boy Butter Desensitizing Lubricant
Boy Butter Extreme Desensitizing Lubricant
Boy Butter Extreme H2O Desensitizing Lubricant
Brace Relief
Budpak Baby Teething Oral Pain Reliever
Budpak Oral Maximum Strength
C07527
CAS-94-09-7
CHEBI:116735
CHEMBL278172
CID2337
Carmex Cold Sore Treatment External Analgesic
Caswell No. 430A
Cepacol Fizzlers
Cepacol Sensations Hydra
Cepacol Sensations Sore Throat Hydra citrus splash
Cepacol Sensations Warming
Certus Sting Relief Prep Pad
Chloraseptic
Chloraseptic Warming Sore Throat
Colgate Orabase
Comfortcaine Topical Anesthetic
Cvs Fast Acting Baby Teething
Cvs Maximum Strength
Cvs Maximum Strength Boil Relief
Cvs Oral Anesthetic
Cvs Pharmacy Instant Toothache
Cvs Pharmacy Maximum Strength
Cvs Pharmacy Mouth Sore Gel
Cvs Pharmacy Nighttime Oral Pain Relief
D001566
D00552
DB01086
Dental Relief
Dentek Instant Pain Relief Maximum Strength
Dermoplast
Diet Ayds
DivK1c_000932
Dollar General Toothache Relief
Dukal Sting Relief Pad
E1501_SIGMA
EINECS 202-303-5
EPA Pesticide Chemical Code 097001
ETHYL-P-AMINOBENZOATE
Ethoform
Ethoforme
Ethyl 4-aminobenzoate
Ethyl 4-aminobenzoate hydrochloride
Ethyl 4-aminobenzoic acid
Ethyl Aminobenzoate
Ethyl PABA
Ethyl aminobenzoate
Ethyl aminobenzoate (JP15)
Ethyl aminobenzoate (VAN)
Ethyl aminobenzoic acid
Ethyl p-Aminobenzoate
Ethyl p-Aminophenylcarboxylate
Ethyl p-aminobenzenecarboxylate
Ethyl p-aminobenzoate
Ethyl p-aminobenzoic acid
Ethyl p-aminophenylcarboxylate
Ethylester kyseliny p-aminobenzoove
Ethylester kyseliny p-aminobenzoove [Czech]
Ethylis aminobenzoas
Finafta Baby
Finafta MultiOral
Formate, Benzocaine
Gelato Topical Anesthetic
Good Neighbor Pain Relief
Goodsense Oral Pain Relief
Gps Topical Anesthetic
Gumnumb Topical Anesthetic
HMS1570O05
HMS1920G09
HMS2091M11
HMS502O14
HSDB 7225
Heb Severe Toothache
Herbasoul Male Genital Desensitizer Cream
 
Hurricaine
Hurricaine Topical Anesthetic
Hurricaine Topical Anesthetic Gel
Hurricaine Topical Anesthetic Liquid
Hydrobromide, Benzocaine
Hydrochloride, Benzocaine
I05-0204
IDI1_000932
Identhesin
Insect Bite Relief
Instant Toothache Pain Relief
Intense Cvs Intense Toothache
Iodent Maximum Strength Oral Analgesic
Ismile Topical Anesthetic
Jianze Sting Relief Pads
KBio1_000932
KBio2_000474
KBio2_003042
KBio2_005610
KBio3_001408
KBioGR_000658
KBioSS_000474
Kank-a Mouth Pain
Keloform
Kmart Smart Sense
Kroger Toothache Pain Relief
LS-35847
Leader Oral Analgesic
Little Colds Sore Throat Relief Melt Aways
MLS001331704
MLS002153970
Makesense Junior Pain Relief
Makesense Pain Relief
Male Desensitizer Pleasure Balm
Mandelay Male Genital Desensitizer
Mark 3
Methanesulfonate, Benzocaine
MolPort-000-871-526
Mouth Sore Medication
Mouth Sore Relief Applicator
Mouth Sore Relief Professional Strength
My Fair Baby Instant Pain Relief
NCGC00016352-01
NCGC00094598-01
NCGC00094598-02
NINDS_000932
NSC 122792
NSC 41531
NSC41531
NSC4688
Nene Dente
Norcain
Norcaine
Norcainum
Opahl
Opahl Dye Free
Oprea1_750694
Oprea1_827402
Ora-jel
Orabase-B
Orajel For All Mouth Sores Maximum Strength
Orajel For Cold Sores
Orajel For Toothache Maximum Strength
Orajel Instant Pain Relief Maximum Strength
Orajel Instant Pain Relief Regular Strength
Orajel Instant Relief For Teething Pain
Orajel Instant Relief For Teething Pain Cooling Cucumber
Orajel Instant Relief For Teething Pain Daytime Nighttime Twin Pack
Orajel Instant Relief For Teething Pain Longer Lasting
Orajel Maximum Strength
Orajel Nighttime Instant Relief For Teething Pain Longer Lasting Extra Strength
Orajel Severe Toothache Maximum Strength Fast-Acting Formula
Oral Analgesic Maximum Strength
Oral B Instant Pain Relief
Oral Gel Maximum Strength
Oral Pain Relief Anesthetic Anesthetic
Oral Pain Reliever
Oralabs Cold Sore Treatment
Orthesin
Otocain
Outgro
Pac-dent Top Gel
Pain Relief
Pain Relief Alcohol Swabs
Parathesin
Parathesin (TN)
Parathesine
Physicians Care Sting Relief Pad
Pleasure Balm Kama Sutra
Preboost
Prestwick0_000712
Prestwick1_000712
Prestwick2_000712
Prestwick3_000712
Prestwick_991
Purelife Topical Anesthetic
Quality Choice Maximum Strength Oral Pain Relieving
Red Cross Oral Pain Relief
Rexall Maximum Strength
Rite Aid Baby Care
Rite Aid Liquid Anesthetic Oral Pain Relief
Rite Aid Maximum Strength
Rite Aid Oral Pain Reliever
Rite Aid Professional Strength
SMR000059025
SPBio_000134
SPBio_002844
SPECTRUM1500139
STK043620
Sally Hansen Ouch-relief Numbing Wipes
Sally Hansen Ouch-relief Wax Kit
Sally Hansen Ouch-relief Wax Strip Kit
Sensigel
Severe Oral Pain Reliever
Sheffield Baby Teething Gel
Sheffield Pain Relief
Shunga Male Genital Desensitizer
Slim Mint Gum
Solarcaine
Solu H
Spectrum2_000117
Spectrum3_000314
Spectrum4_000249
Spectrum5_000860
Spectrum_000074
Sting Relief Medicated Pad
Sting Relief Pads
Tanac
Terrasil Boil Pain Relief
Tiger Supply Inc Topical Anesthetic
Top Quality Mfg. Topical Anesthetic
Topcaine
Topcare Maximum Strength
Topical Anesthetic Banana
Topical Anesthetic Bubble Gum
Topical Anesthetic Cherry
Topical Anesthetic Mint
Topical Anesthetic Pina Colada
Topical Anesthetic Raspberry
Topical Anesthetic Strawberry
UNII-U3RSY48JW5
Ultracare Anesthetic Bubble Gum
Ultracare Anesthetic Butter Rum
Ultracare Anesthetic Creme de Menthe
Ultracare Anesthetic Pina Colada
Ultracare Anesthetic Walterberry
WLN: ZR DVO2
Walgreens Baby Teething
Walgreens Intense Toothache
Walgreens Maximum Strength
Walgreens Pain Relieving For Boils
Walgreens Severe Oral Pain Reliever
Walgreens Severe Toothache Relief
Winco Foods Maximum Strength Oral Analgesic
ZINC12358719
Zilactin-b
benzocaine
ethylaminobenzoate-4
h-4-abz-oet
nchembio.182-comp4
p-(Ethoxycarbonyl)aniline
p-Aminobenzoate
p-Aminobenzoic acid
p-Aminobenzoic acid ethyl ester
p-Aminobenzoic acid, ethyl ester
p-Aminobenzoic ethyl ester
p-Carbethoxyaniline
p-Ethoxycarboxylic Aniline
p-Ethoxycarboxylic aniline
3
DopamineapprovedPhase 4, Phase 3, Phase 2, Phase 1281462-31-7, 51-61-6681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine Hcl
Dopamine Hydrochloride
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
 
KBio1_000780
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
4
Pramipexoleapproved, investigationalPhase 4, Phase 3, Phase 2135104632-26-059868, 119570
Synonyms:
(-)-Pramipexole
(6S)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
(6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
(6S)-N6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
(S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole
(S)-N  6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
104632-26-0
111GE001
2-amino-4,5,6,7-tetrahydro-6-propylaminobenzothiazole
2-amino-6-propylaminotetrahydrobenzothiazole
AC1L3P1T
BIDD:GT0250
C10H17N3S
CHEBI:8356
CHEMBL301265
CID119570
CPD000449298
D05575
DivK1c_006916
Furfuryl Acetate
HMS2051A21
HMS2090C15
KBio1_001860
KBio2_002340
KBio2_004908
KBio2_007476
 
KBioSS_002343
LS-40722
MLS000758250
MLS001423952
Mirapex
MolPort-003-849-957
NCGC00167441-01
Pramipexol
Pramipexol [Spanish]
Pramipexole
Pramipexole (USAN/INN)
Pramipexole 2HCl Monohydrate
Pramipexole Dihydrochloride Extended-Release
Pramipexole [USAN:INN]
Pramipexole hydrochloride
Pramipexolum
Pramipexolum [Latin]
SAM001247006
SBB070477
SMR000449298
SND-919
SUD919CL2Y
SpecPlus_000820
Spectrum5_001453
Spectrum_001838
U-98528E
pramipexole
5
Ropiniroleapproved, investigationalPhase 4, Phase 17291374-20-8, 91374-21-95095, 497540
Synonyms:
1,3-Dihydro-4-(2-(dipropylamino)ethyl)-2H-indol-2-one monohydrochloride
2(H)-Indol-2-one, 4-(2-(dipropylamino)ethyl)-1,3-dihydro-, monohydrochloride
2H-Indol-2-one, 1,3-dihydro-4-(2-(dipropylamino)ethyl)-, monohydrochloride
2H-Indol-2-one, 4-[2-(dipropylamino)ethyl]-1,3-dihydro-, hydrochloride (1:1)
4-(2-(Dipropylamino)ethyl)-2-indolinone monohydrochloride
4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one
4-[2-(Dipropylamino)ethyl]indoline-2-one
4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one hydrochloride
4-[2-(dipropylamino)ethyl]-1,3-dihydroindol-2-one
4-[2-(dipropylamino)ethyl]-1,3-dihydroindol-2-one hydrochloride
91374-20-8
91374-20-8 (hydrochloride)
91374-21-9
91374-21-9 (Parent)
AB1004799
AC-735
AC1L1JLL
AC1L2ABS
AC1Q3EQJ
AR-1L3132
Adartrel
BIDD:GT0826
BRD-K15933101-003-01-2
C07564
CHEBI:8888
CHEMBL1200411
CHEMBL589
CID5095
CID68727
D00784
D08489
DB00268
EU-0101101
HMS2093K04
I06-0692
I06-0693
JZP-7
L000520
LS-83828
LS-83890
Lopac-R-4152
Lopac0_001101
MolPort-003-666-598
MolPort-003-987-439
NCGC00015893-01
NCGC00015893-04
 
NCGC00094373-01
NCGC00096064-01
NCGC00096064-02
NVD-434
R 4152
ReQuip
ReQuip CR
ReQuip LP
ReQuip XL
ReQuip XR
Repreve
Requip
Requip (TN)
Requip XL
Ropinirol
Ropinirol [INN-Spanish]
Ropinirole
Ropinirole (INN)
Ropinirole 12 mg
Ropinirole 2 mg
Ropinirole 4 mg
Ropinirole 6 mg
Ropinirole 8 mg
Ropinirole HCl
Ropinirole Hydrochloride
Ropinirole [INN:BAN]
Ropinirole hydrochloride
Ropinirole hydrochloride (JAN/USAN)
Ropinirole hydrochloride [USAN]
Ropinirolum
Ropinirolum [INN-Latin]
Ropitor
Ropitor (TN)
SK&F 101468
SK&F 101468-A
SK&F-101,468
SK&F-101468-A
SK&F-101468A
SKF 101468
SKF 101468-A
SPECTRUM1505178
ST51051236
TL8005858
TL8005859
UNII-030PYR8953
UNII-D7ZD41RZI9
ropinirol
6
Gabapentinapproved, investigationalPhase 4, Phase 325460142-96-33446
Synonyms:
1-(Aminomethyl)-cyclohexaneacetic acid
1-(Aminomethyl)cyclohexaneacetic acid
2-[1-(aminomethyl)cyclohexyl]acetic acid
60142-96-3
AC-1485
AC1L1FYE
AC1Q53PH
AKOS000280865
Aclonium
Apo-Gabapentin
Apotex brand of gabapentin
Aventis brand of gabapentin
BB_SC-1512
BIDD:GT0656
BPBio1_000993
BRN 2359739
BSPBio_000901
C040029
C9H17NO2
CAS-60142-96-3
CCRIS 7210
CHEBI:188316
CHEBI:42797
CHEMBL940
CI 945
CI-945
CID3446
D00332
DB00996
DDS-2003
DM-1796
DM-5689
EINECS 262-076-3
EU-0100582
G-154
G0318
G154_SIGMA
GBN
GOE 2450
Gabapen
Gabapentin
Gabapentin (JAN/USAN/INN)
Gabapentin GR
Gabapentin Hexal
Gabapentin Kit
Gabapentin Stada
Gabapentin [USAN:INN:BAN]
Gabapentin-ratiopharm
Gabapentina
Gabapentine
Gabapentine [INN-French]
Gabapentino
Gabapentino [INN-Spanish]
Gabapentino [Spanish]
Gabapentinum
 
Gabapentinum [INN-Latin]
Gabapetin
Go 3450
Goe-3450
Gralise
Gralise Starter Pack
HMS1570N03
HMS2089J03
HSDB 7364
Hexal brand of gabapentin
I06-0677
L000733
LS-7194
Lopac-G-154
Lopac0_000582
MLS000069358
MolPort-000-883-862
NCGC00015466-01
NCGC00015466-02
NCGC00015466-06
NCGC00015466-09
NCGC00016891-01
NCGC00021545-02
NCGC00021545-04
NCGC00021545-05
NSC742194
Neurontin
Neurontin (TN)
Novo-Gabapentin
Novo-Gabapentine
Novopharm brand of gabapentin
PMS-Gabapentin
Parke Davis brand of gabapentin
Pfizer brand of gabapentin
Pharmascience brand of gabapentin
Prestwick0_000861
Prestwick1_000861
Prestwick2_000861
Prestwick3_000861
Prestwick_151
S2133_Selleck
SMR000058311
SPBio_002822
STK598009
Serada
Stadapharm brand of gabapentin
TL8003814
Tocris-0806
UNII-6CW7F3G59X
Vultin
Warner-Lambert brand of gabapentin
[1-(AMINOMETHYL)CYCLOHEXYL]ACETIC ACID
gabapentin
gabapentin (Neurontin)
gabapentina
gabapentinium
ratiopharm brand of gabapentin
7Dopamine AgonistsPhase 4, Phase 3, Phase 2, Phase 1476
8Calcium, DietaryPhase 4, Phase 33529
9N 0437Phase 4, Phase 383
10Deamino Arginine VasopressinPhase 465
11Arginine VasopressinPhase 4163
12VasopressinsPhase 4159
13CoagulantsPhase 4983
14Ferric CompoundsPhase 4, Phase 2114
15
Gamma-Aminobutyric acidPhase 414456-12-2119
Synonyms:
3-Carboxypropylamine
4-Aminobutanoate
4-Aminobutanoic acid
4-Aminobutyrate
4-Aminobutyric acid
Aminalon
GABA
Gaballon
Gamarex
Gammalon
Gammalone
Gammar
Gammasol
 
Mielogen
Mielomade
Omega-Aminobutyrate
Omega-Aminobutyric acid
Piperidate
Piperidic acid
Piperidinate
Piperidinic acid
gamma Aminobutyrate
gamma Aminobutyric acid
gamma-Aminobutyrate
gamma-Aminobutyric acid
w-Aminobutyrate
w-Aminobutyric acid
16tannic acidNutraceuticalPhase 4, Phase 31536
17arginineNutraceuticalPhase 4346
18
LevodopaapprovedPhase 333959-92-76047
Synonyms:
(-)-(3,4-Dihydroxyphenyl)alanine
(-)-3-(3,4-Dihydroxyphenyl)-L-alanine
(-)-3-(3,4-dihydroxyphenyl)-L-alanine
(-)-Dopa
(2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate
(2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid
(−)-3-(3,4-dihydroxyphenyl)-L-alanine
(−)-dopa
.Beta.-(3, 4-Dihydroxyphenyl)alanine
.Beta.-(3,4-Dihydroxyphenyl)-L-alanine
1E83F927-C221-46AA-B90A-81B33C5F3868
2-Amino-3-(3,4-dihydroxyphenyl)propanoic acid
23734-74-9
25525-15-9
3, 4-Dihydroxy-L-phenylalanine
3, 4-Dihydroxyphenylalanine
3,4-DIHYDROXYPHENYLALANINE
3,4-Dihydroxy-L-phenylalanine
3,4-Dihydroxyphenyl-L-alanine
3,4-Dihydroxyphenylalanine
3,4-Dihydroxyphenylalanine (VAN)
3,4-dihydroxy-L-phenylalanine
3,4-dihydroxyphenylalanine
3-(3,4-Dihydroxypheny
3-(3,4-Dihydroxyphenyl)-L-alanine
3-Hydroxy-L-tyrosine
34241-25-3
37830_FLUKA
587-45-1
59-92-7
72572-99-7
72573-00-3
88250-23-1
90638-38-3
AC-11686
AC1L1LOR
AC1Q4U7F
BIDD:GT0158
BPBio1_000059
BSPBio_000053
BSPBio_002354
Bendopa
Bio-0575
Biodopa
Brocadopa
C00355
C9H11NO4
CAS-59-92-7
CCRIS 3766
CHEBI:15765
CHEMBL1009
CID6047
Cerepap
Cidandopa
D 9628
D00059
D0600
D9628
D9628_SIGMA
DAH
DB01235
DOPA
Deadopa
Dihydroxy-L-phenylalanine
Dihydroxyphenylalanine
DivK1c_000452
Dopa
Dopaflex
Dopaidan
Dopal
Dopal-Fher
Dopal-fher
Dopalina
Dopar
Dopar (TN)
Doparkine
Doparl
Dopasol
Dopaston
Dopaston SE
Dopastone
Dopastral
Dopicar
Doprin
EINECS 200-445-2
EU-0100454
Eldopal
Eldopar
Eldopatec
Eurodopa
HMS1568C15
HMS1922J14
HMS2090O08
HMS2093N04
HMS501G14
HSDB 3348
Helfo DOPA
 
Helfo-Dopa
Helfo-dopa
IDI1_000452
IV Levodopa
InChI=1/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14
Insulamina
KBio1_000452
KBio2_000934
KBio2_003502
KBio2_006070
KBioGR_001177
KBioSS_000934
L Dopa
L(-)-Dopa
L-(-)-Dopa
L-(3, 4-Dihydroxyphenyl)-.alpha.-alani
L-(3, 4-Dihydroxyphenyl)alanine
L-(o-Dihydroxyphenyl)alanine
L-.Beta.-(3,4-Dihydroxyphenyl)alanine
L-3,4-Dihydroxyphenylalanine
L-3,4-dihydroxyphenylalanine
L-3-(3,4-Dihydroxyphenyl)-Alanine
L-3-(3,4-Dihydroxyphenyl)alanine
L-3-Hydroxytyrosine
L-4-5-Dihydroxyphenylalanine
L-DOPA
L-DOPA, Parcopa, Atamet, Stalevo, Madopar, Prolopa, Dopar, 3,4-Dihydroxyphenylalanine, Levodopa
L-Dihydroxyphenylalanine
L-Dopa
L-O-Dihydroxyphenylalanine
L-b-(3,4-Dihydroxyphenyl)-a-alanine
L-beta-(3,4-Dihydroxyphenyl)-alpha-alanine
L-beta-(3,4-Dihydroxyphenyl)alanine
L-o-Hydroxytyrosine
LS-255
Laradopa
Larodopa
Ledopa
Levedopa
Levodopa
Levodopa (JP15/USP)
Levodopa (JP15/USP/INN)
Levodopa [USAN:INN:BAN:JAN]
Levodopum
Levodopum [INN-Latin]
Levopa
Lopac-D-9628
Lopac0_000454
MLS000028514
Maipedopa
MolPort-000-856-937
NCGC00015384-01
NCGC00016270-01
NCGC00016270-06
NCGC00093869-04
NINDS_000452
NSC 118381
NSC118381
PDSP1_001541
PDSP2_001525
Parda
Pardopa
Prestwick0_000017
Prestwick1_000017
Prestwick2_000017
Prestwick3_000017
Prestwick_185
Prodopa
Ro 4-6316
S1726_Selleck
SDCCGMLS-0066924.P001
SMR000058312
SPBio_000391
SPBio_001974
SPECTRUM2300205
Sobiodopa
Spectrum2_000496
Spectrum4_000539
Spectrum5_001899
Spectrum_000454
Syndopa
UNII-46627O600J
Veldopa
Weldopa
b-(3,4-Dihydroxyphenyl)-L-alanine
b-(3,4-Dihydroxyphenyl)-a-L-alanine
b-(3,4-Dihydroxyphenyl)alanine
beta-(3,4-Dihydroxyphenyl)-L-alanine
beta-(3,4-Dihydroxyphenyl)-alpha-L-alanine
beta-(3,4-Dihydroxyphenyl)-alpha-alanine
beta-(3,4-Dihydroxyphenyl)alanine
bmse000322
component of Sinemet
l)-L-alanine
nchembio.2007.55-comp26
nchembio.89-comp9
ne
β-(3,4-dihydroxyphenyl)alanine
19
Pregabalinapproved, illicit, investigationalPhase 3327148553-50-85486971
Synonyms:
(3S)-3-(aminomethyl)-5-methylhexanoic acid
(R-)-3-isobutyl GABA
(S)-3-(Aminomethyl)-5-methylhexanoic acid
(S)-3-Isobutyl gaba
(S+)-3-isobutyl GABA
121GE001
148553-50-8
3-Isobutyl gaba
3-isobutyl GABA
AC-1158
AC1NUP03
AKOS005145504
C080245
C8H17NO2
CHEBI:236161
CHEMBL1059
CI 1008
CI-1008
CID5486971
 
D02716
DB00230
FT-0080911
HSDB 7530
LS-75191
Lyrica
Lyrica (TN)
MolPort-000-861-733
PD 144723
PD-144723
Pregabalin
Pregabalin (JAN/USAN/INN)
Pregabalin [USAN]
Pregablin
S-(+)-3-isobutylgaba
S1731_Selleck
SBB062901
TL8001062
TOS-BB-0910
UNII-55JG375S6M
20
Caffeineapproved, NutraceuticalPhase 331758-08-22519
Synonyms:
07E4FB58-FD79-4175-8E3D-05BF96954522
1,3,7-Trimethyl-2,6-dioxopurine
1,3,7-Trimethyl-3,7-dihydro-1H-purine-2,6-dione
1,3,7-Trimethylpurine-2,6-dione
1,3,7-Trimethylxanthine
1,3,7-trimethylpurine-2,6-dione
1,3,7-trimethylxanthine
1-3-7-TRIMETHYLXANTHINE
1-Methyl-Theobromine
1-methyltheobromine
137X
1gfz
1l5q
1l7x
27602_FLUKA
2a3b
3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion
3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
3,7-dihydro-1,3,7-trimethyl-1H-purine
5-26-13-00558 (Beilstein)
58-08-2
7-Methyl Theophylline
7-Methyltheophylline
7-methyltheophylline
71701-02-5
75035_FLUKA
95789-13-2
A.S.A. and Codeine Compound
AC-12774
AC1L1DV2
AC1Q3Z23
ACon1_000085
AI3-20154
AKOS000121334
Alert
Alert-Pep
Alert-pep
Allertness Aid
Anacin Maximum Strength
Anhydrous caffeine
Anhydrous caffeine (JP15)
Anhydrous caffeine (TN)
Anoquan
Awake
BIDD:ER0554
BIDD:GT0632
BIDD:PXR0172
BIM-0050216.0001
BRD-K02404261-001-02-7
BRD-K02404261-001-03-5
BRN 0017705
BSPBio_001921
Berlin-Chemie Brand of Caffeine
Bio-0579
Bio1_000473
Bio1_000962
Bio1_001451
Bristol-Myers Squibb Brand of Caffeine
C 0750
C07481
C0750_SIAL
C1778_SIAL
C2042
C6035_FLUKA
C6035_SIGMA
C7731_SIAL
C8960_SIAL
CCRIS 1314
CFF
CHEBI:27732
CHEMBL113
CID2519
CU-01000012617-3
Cafamil
Cafcit
Cafecon
Cafeina
Cafergot
Cafeína
Caffedrine
Caffedrine Caplets
Caffein
Caffeina
Caffeina [Italian]
Caffeine
Caffeine (USP)
Caffeine (natural)
Caffeine Citrate
Caffeine Pure
Caffeine [BAN:JAN]
Caffeine citrate
Caffeine solution
Caffeine, Anhydrous
Caffeine, Monohydrate
Caffeine, Synthetic
Caffeine, anhydrous
Caffeine, synthetic
Caffine
Cafipel
Caféine
Circle K Nosnooze
Coffein
Coffein [German]
Coffeine
Coffeinum
Coffeinum N
Coffeinum Purrum
Compound 65
Conrx Alert
D002110
D00528
DB00201
DHC Plus
DHCplus
Darvon Compound
Darvon Compound-65
Dasin
Dexitac
Dexitac Stay Alert Stimulant
Dhc Plus
Diurex
Diurex Ultra
Diurex WaterCaps
DivK1c_000730
Drowz Away Maximum strength
Durvitan
EINECS 200-362-1
EU-0100228
Eldiatric C
Enerjets
Equaline Stay Awake
Ercatab
Esgic
Esgic-Plus
FEMA No. 2224
Femcet
Fioricet
Fiorinal
GlaxoSmithKline Brand of Caffeine
Good Neighbor Pharmacy Stay Awake
Good Sense Stay Awake
Guaranine
HMS1920I09
HMS2091O11
HMS502E12
HSDB 36
Health Mart Stay Awake
Healthy Accents Stay Awake
Hycomine
Hycomine Compound
I14-4386
IDI1_000730
 
Invagesic
Invagesic Forte
KBio1_000730
KBio2_001781
KBio2_004349
KBio2_006917
KBio3_001141
KBioGR_002325
KBioSS_001781
Keep Alert
Kofein
Kofein [Czech]
Koffein
Koffein [German]
L000155
LS-237
Lanorinal
Leader Alertness Aid
Lil Drug Store Nosnooze
Lopac-C-0750
Lopac0_000228
MEGxp0_001350
MLS001055341
MLS001056714
MLS001066409
Mateina
Mateína
Maximum Strength Caffeine
Maximum Strength Snapback Stimulant Powders
Maximum Strength Stay Awake
Medigesic Plus
Merck dura Brand of Caffeine
Methyltheobromide
Methyltheobromine
Methylxanthine theophylline
Midol Maximum Strength
Migergot
Miudol
MolMap_000054
MolPort-000-730-850
Monohydrate Caffeine
Monomethyl Derivative of Theophylline
Monomethyl derivative of Theophylline
NCGC00015208-01
NCGC00015208-02
NCGC00015208-04
NCGC00015208-14
NCGC00090699-01
NCGC00090699-02
NCGC00090699-03
NCGC00090699-04
NCGC00090699-05
NCGC00090699-06
NCGC00090699-07
NCGC00090699-08
NCGC00090699-09
NCGC00168808-01
NCGC00168808-02
NCI-C02733
NCIOpen2_008255
NINDS_000730
NSC 5036
NSC5036
Nano Ppc
Natural Caffeinum
Nix Nap
No Doz
No-Doz
Nodaca
Nodoz Maximum Strength Caplets
Norgesic
Norgesic Forte
Organex
Orphengesic
Orphengesic Forte
P-A-C Analgesic Tablets
PDSP1_001016
PDSP1_001235
PDSP2_001000
PDSP2_001219
Passauer Brand of Caffeine
Pep-Back
Pep-back Peak Performance
Pep-back Ultra
Percoffedrinol N
Percutafeine
Phensal
Pierre Fabre Brand of Caffeine
Probes1_000150
Probes2_000128
Propoxyphene
Propoxyphene Compound 65
Propoxyphene Compound-65
Quick Pep
Quick-Pep
Refresh'n
Republic Drug Brand of Caffeine
SDCCGMLS-0064595.P001
SDCCGMLS-0064595.P002
SK 65 Compound
SK-65 Compound
SMR000326667
SPBio_001222
SPECTRUM1500155
STK177283
Seid Brand of Caffeine
Smart Sense Stay Awake
Sohmed Alertness Aid
Spectrum2_001261
Spectrum3_000321
Spectrum4_001782
Spectrum5_000423
Spectrum_001301
Stay Alert Aid
Stay Awake
Stay Awake Maximum Strength
Stay Awake Maximum strength
Stim
Sunmark Stay Awake
Synalgos-Dc
TNP00310
Teina
Thein
Theine
Theobromine ME
Theobromine Me
Theophylline ME
Theophylline Me
Theophylline, 7-methyl
Thompson Brand 1 of Caffeine
Thompson Brand 2 of Caffeine
Tirend
Topcare Stay Awake maximum strength
Tri-Aqua
Triad
UNII-3G6A5W338E
Ultra Pep-Back
Vivarin
W222402_ALDRICH
WLN: T56 BN DN FNVNVJ B1 F1 H1
Wake-Up
Wigraine
Xanthine, 1,3,7-trimethyl
ZINC00001084
bmse000206
cafeine
caffeine
caffenium
component of Cafergot
nchembio.243-comp7
nchembio.63-comp5
nchembio774-comp2
teina
21Benserazide, levodopa drug combinationPhase 39
22BenserazidePhase 312
23Caffeine citratePhase 316
24
Citric AcidnutraceuticalPhase 378477-92-9311
Synonyms:
2-Hydroxy-1,2,3-propanetricarboxylate
2-Hydroxy-1,2,3-propanetricarboxylic acid
2-Hydroxytricarballylic acid
3-Carboxy-3-hydroxypentane-1,5-dioate
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Aciletten
Anhydrous citrate
Anhydrous citric acid
Chemfill
Citraclean
 
Citrate
Citretten
Citric acid
Citro
Citronensäure
E 330
Hydrocerol A
Kyselina citronova
Suby G
Uro-trainer
beta-Hydroxytricarballylate
beta-Hydroxytricarballylic acid
25CitrateNutraceuticalPhase 3784
26Ferric oxide, saccharatedPhase 271
27Iron SupplementNutraceuticalPhase 2153
28Omega 3 Fatty AcidNutraceutical890
29OliveNutraceutical212

Interventional clinical trials:

(show all 32)
idNameStatusNCT IDPhase
1Effects of Neupro on Cardiovascular Observations in Patients With Restless Legs SyndromeCompletedNCT01455012Phase 4
2Desmopressin Melt: Impact on Sleep and Daytime FunctioningCompletedNCT01645475Phase 4
312-week Polysomnography Study of Ropinirole Controlled Release for Restless Legs SyndromeCompletedNCT00373542Phase 4
4Restless Legs Syndrome With Iron Deficiency or Anaemia in the 3rd Trimester of PregnancyCompletedNCT01245777Phase 4
5Effect of Rotigotine Patch Treatment on Cardiovascular Markers in Idiopathic Restless Legs SyndromeRecruitingNCT01823770Phase 4
6Effects of Gabapentin Enacarbil on Arousals, Heart Rate, Blood Pressure and PLMs in Restless Legs SyndromeNot yet recruitingNCT02424695Phase 4
7Butrans for Treatment of Restless Legs SyndromeWithdrawnNCT02138357Phase 4
8A Sleep Laboratory Study to Investigate the Safety and Efficacy of the Rotigotine Skin Patch in Subjects With Restless Legs Syndrome and End-Stage Renal Disease Requiring HemodialysisCompletedNCT01537042Phase 3
9Polysomnography Study of GSK1838262 Extended Release Tablets Versus Placebo in RLS and Associated Sleep DisturbanceCompletedNCT00748098Phase 3
10A Sleep Lab Trial to Investigate the Efficacy and Safety of Transdermal Rotigotine in Subjects With Idiopathic Restless Legs SyndromeCompletedNCT00275236Phase 3
11Caffeine for Apnea of Prematurity-Sleep (CAP-S) StudyCompletedNCT01020357Phase 3
12Polysomnography Study Of Pregabalin And Pramipexole Versus Placebo In Patients With Restless Legs Syndrome And Associated Sleep DisturbanceCompletedNCT00991276Phase 3
13Assess Efficacy and Safety of the Dopamine Agonist Pramipexole Versus Levodopa / Benserazide (Madopar® DR) in Patients With Restless Legs SyndromeCompletedNCT00144209Phase 3
14Rotigotine Effect on All-day Functioning and Quality of Life in Subjects With Moderate to Severe Restless Legs Syndrome (RLS)CompletedNCT01569464Phase 3
15The Effects of Aplindore on the Treatment of Signs and Symptoms of Restless Legs SyndromeCompletedNCT00626418Phase 2
16Pramipexole (BI-Sifrol®) Orally Once Daily for 6 Weeks in Patients With Primary Restless Legs SyndromeCompletedNCT00152997Phase 2
17Dose Finding Study of Pramipexole (Sifrol) in Patients With Idiopathic Restless Legs Syndrome (RLS)CompletedNCT00239486Phase 2
18Iron Sucrose In The Treatment of Restless Legs Syndrome: Safety of Three Dose Regimens as Evaluated by Clinical AssessmentsCompletedNCT00895232Phase 2
19Iron Treatment of Sleep Disorders in Children With Autism Spectrum DisorderActive, not recruitingNCT01745497Phase 2
20Ropinirole Tablets In Young Patients With Restless Legs SyndromeCompletedNCT00140712Phase 1
21Effect of Intermittent Hemodialysis on Sleep Apnea Syndrome in End Stage Renal Disease PatientsCompletedNCT01860209
22Dopamine Transporter Density Profiles in Patients With Periodic Limb MovementsCompletedNCT01365364
23Effect of Ropinirole on Spinal Cord Reflexes and Restless Legs SyndromeCompletedNCT00051961
24Cervical Activation During Elastic and Manual ResistanceCompletedNCT02124304
25Effect of Beginning a Renal Replacement Therapy on Obstructive Sleep Apnea in End Stage Renal Disease PatientsRecruitingNCT02073344
26Effect of Renal Transplantation on Obstructive Sleep Apnea in End Stage Renal Disease Patients (SASinTx)RecruitingNCT02020642
27Cardiovascular Prevention Program RegistryRecruitingNCT01975181
28Impact of Different Dialysis on Sleep Apnea in Patients With Renal FailureRecruitingNCT00380848
29Infra-slow Oscillations During SleepRecruitingNCT02532608
30Exploring the Use of Non-invasive Neuromodulation Combined With Exercise in People With Advanced Multiple Sclerosis (MS)Active, not recruitingNCT02252666
31A Study of Sleep Patterns in Patients Performing Nocturnal Home Dialysis Utilising the VIVIA SystemNot yet recruitingNCT02583347
32Verification of Computerized Sleep-wake Analysis in Sleep DisordersNot yet recruitingNCT02412527

Search NIH Clinical Center for Periodic Limb Movement Disorder


Cochrane evidence based reviews: Nocturnal Myoclonus Syndrome

Genetic Tests for Periodic Limb Movement Disorder

About this section

Anatomical Context for Periodic Limb Movement Disorder

About this section

MalaCards organs/tissues related to Periodic Limb Movement Disorder:

33
Testes, Globus pallidus, Brain

Animal Models for Periodic Limb Movement Disorder or affiliated genes

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MGI Mouse Phenotypes related to Periodic Limb Movement Disorder:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053698.5DRD2, FXYD1, GLRA1, HTR2A, HTR2C, SLC6A4
2MP:00053978.0CHRNA4, DRD2, GLRA1, HAMP, LCK, PER1
3MP:00036317.6CHRNA4, DRD2, GLRA1, HTR1A, HTR2C, PER1
4MP:00053867.5CHRNA4, DRD2, GLRA1, HTR1A, HTR2A, HTR2C

Publications for Periodic Limb Movement Disorder

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Articles related to Periodic Limb Movement Disorder:

(show top 50)    (show all 69)
idTitleAuthorsYear
1
Rotigotine effect on sleep in a de novo Parkinson's Disease patient affected by periodic limb movement disorder. (26578038)
2015
2
Migraine and periodic limb movement disorders in sleep in children: a preliminary case-control study. (23815623)
2013
3
Night-to-night variability of periodic leg movements during sleep in restless legs syndrome and periodic limb movement disorder: comparison between the periodicity index and the PLMS index. (23068780)
2013
4
Bilateral globus pallidus internus deep brain stimulation in Parkinson's disease with periodic limb movement disorder. (23344876)
2013
5
Update to the AASM Clinical Practice Guideline: "The treatment of restless legs syndrome and periodic limb movement disorder in adults-an update for 2012: practice parameters with an evidence-based systematic review and meta-analyses". (22851800)
2012
6
All the wrong moves: a clinical review of restless legs syndrome, periodic limb movements of sleep and wake, and periodic limb movement disorder. (20488295)
2010
7
Restless legs syndrome and periodic limb movements disorder in the pediatric population. (20859209)
2010
8
Ropinirole in restless legs syndrome and periodic limb movement disorder. (20421915)
2010
9
Periodic leg movements during sleep and periodic limb movement disorder in patients presenting with unexplained insomnia. (19109055)
2009
10
Parents of children with periodic limb movement disorder versus sleep-disordered breathing report greater daytime mood and behavior difficulties in their child: the importance of using ICSD-2nd Edition criteria to define a PLMD study group. (19568964)
2009
11
Pediatric restless legs syndrome and periodic limb movement disorder: parent-child pairs. (19332386)
2009
12
Restless legs syndrome and periodic limb movement disorder in children and adolescents. (18555195)
2008
13
Periodic limb movements in sleep and periodic limb movement disorder. (17235435)
2007
14
Periodic limb movement disorder in children. (16798596)
2006
15
Periodic leg movements in sleep and periodic limb movement disorder: prevalence, clinical significance and treatment. (16762807)
2006
16
Selected sleep disorders: restless legs syndrome and periodic limb movement disorder, sleep apnea syndrome, and narcolepsy. (17118276)
2006
17
Periodic limb movement disorder: an unusual mechanism of twiddling and potential benefit from cardiac resynchronization therapy. (15733189)
2005
18
Abnormal H-reflexes in periodic limb movement disorder; impact on understanding the pathophysiology of the disorder. (15589198)
2005
19
SLEEP year in review 2003--insomnia, sleep in psychiatric disorders, periodic limb movement disorder/restless legs syndrome, sleep in medical disorders. (15532215)
2004
20
Restless legs syndrome and periodic limb movement disorder in the elderly. (15172211)
2004
21
Practice parameters for the dopaminergic treatment of restless legs syndrome and periodic limb movement disorder. (15164914)
2004
22
Restless legs syndrome and periodic limb movement disorder. (15087209)
2004
23
Periodic limb movement disorder and restless legs syndrome in dialysis patients. (15663636)
2004
24
An update on the dopaminergic treatment of restless legs syndrome and periodic limb movement disorder. (15164915)
2004
25
Activity patterns of leg muscles in periodic limb movement disorder. (14742617)
2004
26
Can periodic limb movement disorder be diagnosed without polysomnography? A case-control study. (14592358)
2003
27
Different sleep characteristics in restless legs syndrome and periodic limb movement disorder. (14592346)
2003
28
Cognitive and behavioral anomalies among insomnia patients with mixed restless legs and periodic limb movement disorder. (15600136)
2003
29
Periodic limb movement disorder of sleep in children. (12603789)
2003
30
Subjective sleep quality and suggested immobilization test in restless leg syndrome and periodic limb movement disorder. (12047601)
2002
31
Prevalence of restless legs syndrome and periodic limb movement disorder in the general population. (12127170)
2002
32
EEG mapping, psychometric, and polysomnographic studies in restless legs syndrome (RLS) and periodic limb movement disorder (PLMD) patients as compared with normal controls. (14592166)
2002
33
Restless legs syndrome and periodic limb movement disorder. (12587366)
2002
34
Exogenous melatonin in periodic limb movement disorder: an open clinical trial and a hypothesis. (11247054)
2001
35
Misinterpretation of sleep-breathing disorder by periodic limb movement disorder. (11868152)
2001
36
Periodic limb movement disorder : a clinical and polysomnographic study. (11799409)
2001
37
Sleep laboratory studies in periodic limb movement disorder (PLMD) patients as compared with normals and acute effects of ropinirole. (12404588)
2001
38
Valproate for sleep consolidation in periodic limb movement disorder. (11001243)
2000
39
An FDOPA PET study in patients with periodic limb movement disorder and restless legs syndrome. (10668725)
2000
40
Bupropion SR reduces periodic limb movements associated with arousals from sleep in depressed patients with periodic limb movement disorder. (11105739)
2000
41
Practice parameters for the treatment of restless legs syndrome and periodic limb movement disorder. An American Academy of Sleep Medicine Report. Standards of Practice Committee of the American Academy of Sleep Medicine. (10566915)
1999
42
Secondary periodic limb movement disorder and restless legs syndrome. (15310483)
1999
43
Differential rates of psychopathology symptoms in periodic limb movement disorder, obstructive sleep apnea, psychophysiological insomnia, and insomnia with psychiatric disorder. (10505823)
1999
44
Moderate to severe periodic limb movement disorder in childhood and adolescence. (10341379)
1999
45
The treatment of restless legs syndrome and periodic limb movement disorder. An American Academy of Sleep Medicine Review. (10566916)
1999
46
Periodic limb movement disorder and restless legs syndrome in children with attention-deficit hyperactivity disorder. (9881529)
1998
47
Periodic limb movement disorder in neuroleptic-induced akathisia. (9642972)
1997
48
Comparison of cognitive-behavioral therapy and clonazepam for treating periodic limb movement disorder. (8843536)
1996
49
Relationship of nasal continuous positive airway pressure to periodic limb movement disorder in a patient without sleep apnea. (8486056)
1993
50
The Babinski response and periodic limb movement disorder. (1627987)
1992

Variations for Periodic Limb Movement Disorder

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Expression for genes affiliated with Periodic Limb Movement Disorder

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Search GEO for disease gene expression data for Periodic Limb Movement Disorder.

Pathways for genes affiliated with Periodic Limb Movement Disorder

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GO Terms for genes affiliated with Periodic Limb Movement Disorder

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Cellular components related to Periodic Limb Movement Disorder according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1integral component of plasma membraneGO:00058878.3DRD2, FXYD1, GLRA1, HTR1A, HTR2A, HTR2C

Biological processes related to Periodic Limb Movement Disorder according to GeneCards Suite gene sharing:

(show all 25)
idNameGO IDScoreTop Affiliating Genes
1startle responseGO:000196410.6DRD2, GLRA1
2negative regulation of synaptic transmission, glutamatergicGO:005196710.6DRD2, HTR2A
3phospholipase C-activating serotonin receptor signaling pathwayGO:000720810.6HTR2A, HTR2C
4temperature homeostasisGO:000165910.5DRD2, HTR2A
5inhibitory postsynaptic potentialGO:006008010.5CHRNA4, GLRA1
6regulation of behaviorGO:005079510.5HTR1A, HTR2A
7regulation of hormone secretionGO:004688310.5HTR1A, HTR2A
8positive regulation of phosphatidylinositol biosynthetic processGO:001051310.5HTR2A, HTR2C
9action potentialGO:000150810.5CHRNA4, GLRA1
10regulation of sodium ion transportGO:000202810.5DRD2, PER1
11response to light stimulusGO:000941610.4DRD2, PER1
12exploration behaviorGO:003564010.4CHRNA4, HTR1A
13positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathwayGO:005148210.4DRD2, HTR2C
14vasoconstrictionGO:004231010.3HTR1A, SLC6A4
15positive regulation of receptor internalizationGO:000209210.3DRD2, HAMP
16serotonin receptor signaling pathwayGO:000721010.3HTR1A, HTR2A, HTR2C
17behavioral response to cocaineGO:004814810.1DRD2, HTR2A
18response to iron ionGO:001003910.1DRD2, HAMP
19cellular calcium ion homeostasisGO:000687410.0DRD2, HTR2A, HTR2C
20regulation of dopamine secretionGO:00140599.8CHRNA4, DRD2, HTR2A
21positive regulation of ERK1 and ERK2 cascadeGO:00703749.8DRD2, HTR2A, HTR2C
22release of sequestered calcium ion into cytosolGO:00512099.8DRD2, HTR2A, HTR2C, LCK
23locomotory behaviorGO:00076269.6CHRNA4, DRD2, HTR2C, VPS13A
24synaptic transmissionGO:00072689.0CHRNA4, GLRA1, HTR2A, HTR2C, SLC6A4
25response to drugGO:00424938.8DRD2, HTR2A, HTR2C, LCK, SLC6A4

Molecular functions related to Periodic Limb Movement Disorder according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1serotonin bindingGO:005137810.4HTR2A, HTR2C
21-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine bindingGO:007188610.3HTR2A, HTR2C
3serotonin receptor activityGO:000499310.0HTR1A, HTR2A, HTR2C
4myosin bindingGO:00170229.6FXYD1, SLC6A4
5drug bindingGO:00081449.4DRD2, HTR2A, HTR2C

Sources for Periodic Limb Movement Disorder

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet