MCID: PRD002
MIFTS: 22

Periodic Limb Movement Disorder malady

Summaries for Periodic Limb Movement Disorder

Sources:
8Disease Ontology, 64Wikipedia, 33MalaCards
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Wikipedia:64 Periodic limb movement disorder (PLMD), previously known as nocturnal myoclonus, is a sleep disorder... more...

MalaCards: Periodic Limb Movement Disorder, also known as nocturnal myoclonus, is related to restless legs syndrome and sleep disorder. An important gene associated with Periodic Limb Movement Disorder is DRD2 (dopamine receptor D2). Affiliated tissues include brain and globus pallidus.

Disease Ontology:8 A sleep disorder that involves involuntary limb movement during sleep.

Aliases & Classifications for Periodic Limb Movement Disorder

Sources:
8Disease Ontology, 45Novoseek, 27ICD9CM, 57SNOMED-CT, 61UMLS, 35MeSH
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Aliases & Descriptions:

periodic limb movement disorder 8 45
nocturnal myoclonus 8


External Ids:

Disease Ontology8 DOID:9207
ICD9CM27 327.51
SNOMED-CT57 418763003
MeSH35 D020189

Related Diseases for Periodic Limb Movement Disorder

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Periodic Limb Movement Disorder via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 12)
idRelated DiseaseScoreTop Affiliating Genes
1restless legs syndrome11.0
2sleep disorder10.9
3sleep apnea10.6
4insomnia10.5
5myoclonus10.4
6attention deficit hyperactivity disorder10.4
7adult syndrome10.4
8parkinson's disease10.2
9narcolepsy10.2
10conduct disorder10.2
11brain disease10.2
12hypersomnia10.1

Graphical network of diseases related to Periodic Limb Movement Disorder:



Diseases related to periodic limb movement disorder

Clinical Features for Periodic Limb Movement Disorder

Drugs & Therapeutics for Periodic Limb Movement Disorder

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

Search CenterWatch for Periodic Limb Movement Disorder

Drug clinical trials:

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Search CenterWatch for Periodic Limb Movement Disorder

Genetic Tests for Periodic Limb Movement Disorder

Anatomical Context for Periodic Limb Movement Disorder

Sources:
33MalaCards
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MalaCards organs/tissues related to Periodic Limb Movement Disorder:

33
Brain, Globus pallidus

Animal Models for Periodic Limb Movement Disorder or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Periodic Limb Movement Disorder

Sources:
51PubMed
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Articles related to Periodic Limb Movement Disorder:

(show top 50)    (show all 70)
idTitleAuthorsYear
1
The validity of the PAM-RL device for evaluating periodic limb movements in sleep and an investigation on night-to-night variability of periodic limb movements during sleep in patients with restless legs syndrome or periodic limb movement disorder using this system. (24269130)
2014
2
Migraine and periodic limb movement disorders in sleep in children: a preliminary case-control study. (23815623)
2013
3
Night-to-night variability of periodic leg movements during sleep in restless legs syndrome and periodic limb movement disorder: comparison between the periodicity index and the PLMS index. (23068780)
2013
4
Treatment of childhood-onset restless legs syndrome and periodic limb movement disorder using intravenous iron sucrose. (23993871)
2013
5
Update to the AASM Clinical Practice Guideline: "The treatment of restless legs syndrome and periodic limb movement disorder in adults-an update for 2012: practice parameters with an evidence-based systematic review and meta-analyses". (22851800)
2012
6
The treatment of restless legs syndrome and periodic limb movement disorder in adults-an update for 2012: practice parameters with an evidence-based systematic review and meta-analyses: an American Academy of Sleep Medicine Clinical Practice Guideline. (22851801)
2012
7
Impaired driving simulation in patients with Periodic Limb Movement Disorder and patients with Obstructive Sleep Apnea Syndrome. (22353445)
2012
8
L-Dopa improves Restless Legs Syndrome and periodic limb movements in sleep but not Attention-Deficit-Hyperactivity Disorder in a double-blind trial in children. (21463967)
2011
9
All the wrong moves: a clinical review of restless legs syndrome, periodic limb movements of sleep and wake, and periodic limb movement disorder. (20488295)
2010
10
Ropinirole in restless legs syndrome and periodic limb movement disorder. (20421915)
2010
11
Periodic leg movements during sleep and periodic limb movement disorder in patients presenting with unexplained insomnia. (19109055)
2009
12
Parents of children with periodic limb movement disorder versus sleep-disordered breathing report greater daytime mood and behavior difficulties in their child: the importance of using ICSD-2nd Edition criteria to define a PLMD study group. (19568964)
2009
13
Pediatric restless legs syndrome and periodic limb movement disorder: parent-child pairs. (19332386)
2009
14
Behavioral Sleep Medicine Interventions for Restless Legs Syndrome and Periodic Limb Movement Disorder. (20161553)
2009
15
Periodic limb movements in sleep and periodic limb movement disorder. (17235435)
2007
16
Periodic limb movement disorder in children. (16798596)
2006
17
Periodic leg movements in sleep and periodic limb movement disorder: prevalence, clinical significance and treatment. (16762807)
2006
18
EFNS guidelines on management of restless legs syndrome and periodic limb movement disorder in sleep. (16987157)
2006
19
Periodic limb movement disorder: an unusual mechanism of twiddling and potential benefit from cardiac resynchronization therapy. (15733189)
2005
20
Abnormal H-reflexes in periodic limb movement disorder; impact on understanding the pathophysiology of the disorder. (15589198)
2005
21
SLEEP year in review 2003--insomnia, sleep in psychiatric disorders, periodic limb movement disorder/restless legs syndrome, sleep in medical disorders. (15532215)
2004
22
Practice parameters for the dopaminergic treatment of restless legs syndrome and periodic limb movement disorder. (15164914)
2004
23
Restless legs syndrome and periodic limb movement disorder. (15087209)
2004
24
Periodic limb movement disorder and restless legs syndrome in dialysis patients. (15663636)
2004
25
An update on the dopaminergic treatment of restless legs syndrome and periodic limb movement disorder. (15164915)
2004
26
The restless legs syndrome and periodic limb movement disorder: a review of management. (15449218)
2004
27
Can periodic limb movement disorder be diagnosed without polysomnography? A case-control study. (14592358)
2003
28
Different sleep characteristics in restless legs syndrome and periodic limb movement disorder. (14592346)
2003
29
Cognitive and behavioral anomalies among insomnia patients with mixed restless legs and periodic limb movement disorder. (15600136)
2003
30
Prevalence of restless legs syndrome and periodic limb movement disorder in the general population. (12127170)
2002
31
EEG mapping, psychometric, and polysomnographic studies in restless legs syndrome (RLS) and periodic limb movement disorder (PLMD) patients as compared with normal controls. (14592166)
2002
32
Clinical symptomatology and treatment of restless legs syndrome and periodic limb movement disorder. (12531131)
2002
33
On "Misinterpretation of sleep-breathing disorder by periodic limb movement disorder" (Sleep Breath 2001;5:131-138). (12244494)
2002
34
Exogenous melatonin in periodic limb movement disorder: an open clinical trial and a hypothesis. (11247054)
2001
35
Misinterpretation of sleep-breathing disorder by periodic limb movement disorder. (11868152)
2001
36
Periodic limb movement disorder : a clinical and polysomnographic study. (11799409)
2001
37
Sleep laboratory studies in periodic limb movement disorder (PLMD) patients as compared with normals and acute effects of ropinirole. (12404588)
2001
38
Restless legs syndrome (RLS) and periodic limb movement disorder (PLMD): acute placebo-controlled sleep laboratory studies with clonazepam. (11313161)
2001
39
Valproate for sleep consolidation in periodic limb movement disorder. (11001243)
2000
40
Bupropion SR reduces periodic limb movements associated with arousals from sleep in depressed patients with periodic limb movement disorder. (11105739)
2000
41
Practice parameters for the treatment of restless legs syndrome and periodic limb movement disorder. An American Academy of Sleep Medicine Report. Standards of Practice Committee of the American Academy of Sleep Medicine. (10566915)
1999
42
Secondary periodic limb movement disorder and restless legs syndrome. (15310483)
1999
43
Differential rates of psychopathology symptoms in periodic limb movement disorder, obstructive sleep apnea, psychophysiological insomnia, and insomnia with psychiatric disorder. (10505823)
1999
44
Moderate to severe periodic limb movement disorder in childhood and adolescence. (10341379)
1999
45
Further studies on periodic limb movement disorder and restless legs syndrome in children with attention-deficit hyperactivity disorder. (10584676)
1999
46
Bupropion, periodic limb movement disorder, and ADHD. (10361776)
1999
47
Periodic limb movement disorder in neuroleptic-induced akathisia. (9642972)
1997
48
The symptomatology of periodic limb movement disorder. (9122564)
1996
49
The Babinski response and periodic limb movement disorder. (1627987)
1992
50
Periodic limb movement disorder is associated with normal motor conduction latencies when studied by central magnetic stimulation--successful use of a new technique. (1519005)
1992

Genetic Variations for Periodic Limb Movement Disorder

Expression for genes affiliated with Periodic Limb Movement Disorder

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Periodic Limb Movement Disorder

Search GEO for disease gene expression data for Periodic Limb Movement Disorder.

Pathways for genes affiliated with Periodic Limb Movement Disorder

Compounds for genes affiliated with Periodic Limb Movement Disorder

GO Terms for genes affiliated with Periodic Limb Movement Disorder

Products for genes affiliated with Periodic Limb Movement Disorder

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  • Proteins
  • Lysates
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Sources for Periodic Limb Movement Disorder

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet