MCID: PRD007
MIFTS: 64

Periodontal Disease

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Periodontal Disease

MalaCards integrated aliases for Periodontal Disease:

Name: Periodontal Disease 12 72 14
Periodontal Diseases 51 41 69
Disease of Supporting Structures of Teeth, Nos 12
Periodontium Disorder 12
Gingival Diseases 69

Classifications:



External Ids:

Disease Ontology 12 DOID:3388
ICD10 32 K05.6
MeSH 41 D010510
NCIt 46 C63743
UMLS 69 C0031090

Summaries for Periodontal Disease

MalaCards based summary : Periodontal Disease, also known as periodontal diseases, is related to periodontosis and periodontitis, aggressive, 1, and has symptoms including oral manifestations, tenderness of gums and snoring. An important gene associated with Periodontal Disease is IL1B (Interleukin 1 Beta), and among its related pathways/superpathways are PEDF Induced Signaling and Innate Immune System. The drugs sodium fluoride and Triclosan have been mentioned in the context of this disorder. Affiliated tissues include bone, testes and kidney, and related phenotypes are homeostasis/metabolism and hematopoietic system

Wikipedia : 72 Periodontitis, also known as gum disease and pyorrhea, is a set of inflammatory diseases affecting the... more...

Related Diseases for Periodontal Disease

Diseases related to Periodontal Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 442)
# Related Disease Score Top Affiliating Genes
1 periodontosis 32.0 CD79A CXCL8 ELANE MMP9 TLR4 TNFSF11
2 periodontitis, aggressive, 1 31.5 CTSC IL1A MMP1 MMP8
3 aggressive periodontitis 31.3 CTSC CXCL8 IL1A IL1B IL6 MMP8
4 gingivitis 31.2 CD79A CXCL8 ELANE GUSB IL1A IL1B
5 arteries, anomalies of 30.4 CRP IL1B IL6 MMP9 TNF
6 apnea, obstructive sleep 30.4 CRP IL6 TNF
7 aphthous stomatitis 30.2 IL1B IL6 TNF
8 root resorption 30.1 IL1A IL1B TNFRSF11B TNFSF11
9 osteoporosis 30.1 CRP IL1A IL1B IL6 TNF TNFRSF11B
10 prostatitis 30.1 CXCL8 IL1B IL6 TNF
11 sleep apnea 30.0 CRP CXCL8 IL6 TNF
12 familial mediterranean fever 30.0 CRP IL1B TNF
13 gingival overgrowth 30.0 IL1A IL6 MMP1 TIMP1
14 cytomegalovirus infection 29.9 CXCL8 IL6 TNF
15 mycobacterium tuberculosis 1 29.9 IL17A TLR2 TLR4 TNF
16 peripheral artery disease 29.9 CRP IL6 TNFRSF11B
17 crohn's disease 29.9 CRP IL1B IL6 TLR4 TNF
18 helicobacter pylori infection 29.8 CXCL8 IL1B TLR4 TNF
19 duodenal ulcer 29.8 CXCL8 IL1B TNF
20 periodontitis, chronic 29.8 IL1B IL6 MMP1 MMP8 TLR2 TNFRSF11B
21 osteoporotic fracture 29.8 IL6 TNFRSF11B
22 bacterial vaginosis 29.8 CXCL8 IL1A IL1B IL6 TLR2 TLR4
23 arthritis 29.7 CXCL8 IL17A IL1A IL1B IL6 MMP1
24 pulmonary disease, chronic obstructive 29.7 CRP CXCL8 ELANE IL6 MMP1 TNF
25 brucellosis 29.7 CRP CXCL8 IL6 TLR4 TNF
26 pulmonary emphysema 29.4 ELANE MMP1 MMP8 MMP9 TIMP1
27 psoriasis 29.4 CXCL8 ELANE IL17A IL1A IL1B IL6
28 systemic lupus erythematosus 29.2 CD79A CRP ELANE IL17A IL1B IL6
29 meningitis 29.2 CRP CXCL8 IL1B IL6 MMP9 TLR2
30 psoriatic arthritis 29.1 CRP IL17A IL1A IL1B MMP1 TNF
31 myocardial infarction 29.0 CRP IL1B IL6 MMP1 MMP2 MMP9
32 rheumatoid arthritis 28.4 CD79A CRP CXCL8 IL17A IL1A IL1B
33 periodontitis 28.4 CRP CTSC CXCL8 ELANE IL17A IL1A
34 inflammatory bowel disease 27.9 CD79A CRP CXCL8 ELANE IL17A IL1A
35 colorectal cancer 27.9 CXCL8 IL1B IL6 MMP1 MMP2 MMP9
36 asthma 27.8 CD79A CXCL8 ELANE IL17A IL1A IL1B
37 ehlers-danlos syndrome, periodontal type, 1 11.1
38 permanent molars, secondary retention of 11.0
39 aplasia of lacrimal and salivary glands 11.0
40 hajdu-cheney syndrome 10.8
41 singleton-merten syndrome 1 10.8
42 ehlers-danlos syndrome, periodontal type, 2 10.8
43 dental abscess 10.8
44 necrotizing ulcerative gingivitis 10.8
45 polyposis, gastric 10.7 IL1B TNF
46 irritant dermatitis 10.7 IL1A IL1B TNF
47 laryngitis 10.7 IL1B IL6 TNF
48 acute vascular insufficiency of intestine 10.6 IL1B IL6 TNF
49 poems syndrome 10.6 IL1B IL6 TNF
50 gastroschisis 10.6 IL1B IL6 MMP8

Graphical network of the top 20 diseases related to Periodontal Disease:



Diseases related to Periodontal Disease

Symptoms & Phenotypes for Periodontal Disease

UMLS symptoms related to Periodontal Disease:


oral manifestations, tenderness of gums, snoring, halitosis

MGI Mouse Phenotypes related to Periodontal Disease:

43 (show all 12)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.39 TLR2 TLR4 TNF TNFSF11 CD79A CRP
2 hematopoietic system MP:0005397 10.36 CD79A CTSC ELANE GUSB IL17A IL1A
3 immune system MP:0005387 10.36 ELANE IL17A IL1A IL1B IL6 MMP1
4 growth/size/body region MP:0005378 10.29 IL6 MMP2 MMP9 TIMP1 TLR2 TLR4
5 cardiovascular system MP:0005385 10.25 CRP IL1A IL1B IL6 MMP2 MMP9
6 integument MP:0010771 10.07 CTSC GUSB IL1A IL1B IL6 MMP9
7 mortality/aging MP:0010768 10.07 TNFSF11 ELANE GUSB IL17A IL1B IL6
8 craniofacial MP:0005382 10.04 GUSB IL17A IL1B MMP2 TNF TNFRSF11B
9 neoplasm MP:0002006 10 CD79A ELANE IL1A IL1B IL6 MMP1
10 limbs/digits/tail MP:0005371 9.87 GUSB MMP9 TIMP1 TLR4 TNF TNFRSF11B
11 respiratory system MP:0005388 9.61 TLR2 TLR4 TNF TNFSF11 IL17A IL6
12 skeleton MP:0005390 9.4 GUSB IL17A IL1B IL6 MMP2 MMP9

Drugs & Therapeutics for Periodontal Disease

Drugs for Periodontal Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 441)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 sodium fluoride Approved Phase 4,Phase 3,Phase 1,Phase 2 7681-49-4
2
Triclosan Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 3380-34-5 5564
3
Metronidazole Approved Phase 4,Phase 3,Phase 2,Phase 1 443-48-1 4173
4
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 564-25-0 54671203
5
Levonorgestrel Approved, Investigational Phase 4 797-63-7, 17489-40-6 13109
6
Amoxicillin Approved, Vet_approved Phase 4,Phase 2,Phase 3 26787-78-0 33613 2171
7
Penicillin V Approved, Vet_approved Phase 4 87-08-1 6869
8
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 51-43-4 5816
9 Racepinephrine Approved Phase 4,Phase 3,Phase 2,Early Phase 1 329-65-7
10
Chlorhexidine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 55-56-1 2713 9552079
11
Hexetidine Approved, Investigational Phase 4 141-94-6
12
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2 22916-47-8 4189
13
Menthol Approved Phase 4,Phase 3,Early Phase 1 2216-51-5 16666
14
Zinc Approved, Investigational Phase 4,Phase 2,Phase 3 7440-66-6 32051 23994
15
Azithromycin Approved Phase 4,Phase 2 83905-01-5 53477736 447043 55185
16
Metformin Approved Phase 4,Phase 2,Phase 3 657-24-9 4091 14219
17
Ciprofloxacin Approved, Investigational Phase 4,Phase 1 85721-33-1 2764
18
Ethanol Approved Phase 4,Phase 3,Phase 2 64-17-5 702
19
Acetaminophen Approved Phase 4,Phase 2,Phase 3 103-90-2 1983
20
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 137-58-6 3676
21
Prilocaine Approved Phase 4 721-50-6 4906
22
Alginic acid Approved, Experimental, Investigational Phase 4 9005-32-7
23
Minocycline Approved, Investigational Phase 4,Phase 3,Phase 1 10118-90-8 5281021
24
Albendazole Approved, Vet_approved Phase 4 54965-21-8 2082
25
Methyl salicylate Approved, Vet_approved Phase 4 119-36-8 4133
26
Thymol Approved Phase 4 89-83-8 6989
27
Alendronate Approved Phase 4,Phase 2,Phase 3 121268-17-5, 66376-36-1 2088
28
Edetic Acid Approved, Vet_approved Phase 4 60-00-4, 62-33-9 6049
29
Simvastatin Approved Phase 4,Phase 2,Phase 3 79902-63-9 54454
30
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 1,Phase 2 9004-61-9 53477741 24759
31
Clarithromycin Approved Phase 4,Phase 2,Phase 3 81103-11-9 84029
32
Etoricoxib Approved, Investigational Phase 4 202409-33-4 123619
33
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757
34
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
35
Moxifloxacin Approved, Investigational Phase 4 151096-09-2, 354812-41-2 152946
36
Norgestimate Approved, Investigational Phase 4 35189-28-7 6540478
37
Montelukast Approved Phase 4 158966-92-8 5281040
38 Cetylpyridinium Approved Phase 4,Phase 2,Phase 3,Phase 1 7773-52-6
39
Silicon Approved, Investigational Phase 4,Phase 1,Phase 2 7440-21-3 4082203
40
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
41
Mepivacaine Approved, Vet_approved Phase 4 96-88-8 4062
42
Ibuprofen Approved Phase 4,Phase 2,Phase 3 15687-27-1 3672
43
Aspirin Approved, Vet_approved Phase 4,Phase 2,Phase 3 50-78-2 2244
44
Zoledronic acid Approved Phase 4 118072-93-8 68740
45
Coal tar Approved Phase 4,Phase 3 8007-45-2
46
Hydrogen peroxide Approved, Vet_approved Phase 4 7722-84-1 784
47
Methyltestosterone Approved Phase 4 58-18-4 6010
48
Testosterone Approved, Investigational Phase 4 58-22-0 6013
49
Melatonin Approved, Nutraceutical, Vet_approved Phase 4 73-31-4 896
50
Lycopene Approved, Investigational, Nutraceutical Phase 4,Phase 1,Phase 2 502-65-8 446925

Interventional clinical trials:

(show top 50) (show all 1150)

# Name Status NCT ID Phase Drugs
1 Clinical Investigation of the Effects of Colgate Total Toothpaste as Compared to a Matching Placebo on Periodontal Disease and Systemic Inflammatory Markers Unknown status NCT02670135 Phase 4 Triclosan Containing Toothpaste;Triclosan Free Toothpaste
2 The Treatment of Periodontal Diseases Unknown status NCT01318928 Phase 4 Metronidazol
3 Norplant and Irregular Bleeding/Spotting Unknown status NCT00064766 Phase 4 doxycycline
4 Effect of Actonel on Periodontal Health of Postmenopausal Women Unknown status NCT00594334 Phase 4 Risedronate
5 Surgical Treatment of Peri-implantitis With and Without Systemically Adjunctive Antibiotics Unknown status NCT02185209 Phase 4 Placebo;Amoxicillin Sandoz;Metronidazole Sanofi;Phenoxymethylpenicillin Meda
6 Role of Stress Reduction Protocol on Outcome of Periodontal Therapy Unknown status NCT02487862 Phase 4
7 Periodontal Therapy in Coronary Artery Patients Unknown status NCT01609725 Phase 4
8 Metronidazole and Amoxicillin for the Treatment of Type 2 Diabetic Subjects With Periodontitis Unknown status NCT02135952 Phase 4 MTZ+AMX
9 Clinical, Microbiological and Biochemical Effects of the Antimicrobial Photodynamic Therapy Unknown status NCT01532674 Phase 4
10 Clinical and Microbiological Effects of an Essential Oils Solution Used as an Adjunct to Daily Oral Hygiene Practices in Chronic Periodontitis Patients in Supportive Care Unknown status NCT01195493 Phase 4
11 Study of Scaling and Root Planing With PerioWave Versus Scaling and Root Planing Alone in Chronic Periodontitis Unknown status NCT00297531 Phase 4
12 SRP in Combination With PERIOWAVE in Comparison to SRP Alone in Chronic Periodontitis Unknown status NCT00296881 Phase 4
13 Methodology Antiseptic Application, Influence on Oral Biofilm. Unknown status NCT02267239 Phase 4 essential oils, immersion;Chlorhexidine, immersion;essential oils, mouthwash;chlorhexidine, mouthwash
14 Evaluation of a Lateral Window Technique Augmentation for Maxillary Sinus Using Ultrasound Activated Pins Unknown status NCT02449707 Phase 4
15 Pinhole Surgical Technique With And Without Use Of Buttons For Treatment Of Multiple Gingival Recessions: RCT Unknown status NCT02632968 Phase 4
16 Laser De-epithelialization for Epithelial Exclusion in Root Coverage Procedure: a Clinical Study Unknown status NCT02626117 Phase 4
17 Platelet Rich Fibrin in the Treatment of Palatal Wounds Unknown status NCT02438046 Phase 4
18 Connective Tissue Graft Versus Mucograft Collagen Matrix for Coverage of Multiple Gingival Recession Defects Unknown status NCT01440426 Phase 4
19 Anticaries Effect of Probiotic Lactobacillus Brevis CD2 (Lb CD2). Unknown status NCT01778699 Phase 4
20 Adhesion of Connective Tissue Around Laser-treated Abutments for Dental Implants - Clinical Trial in Humans Unknown status NCT01954485 Phase 4
21 Relationship of Periodontal Disease Treatment and Type 2 Diabetes Mellitus in the Gullah Population Completed NCT01798225 Phase 4 Placebo;Doxycycline
22 Conventional or Minimally Invasive Surgical Technique for the Treatment of Furcation Defects Using Enamel Matrix Derivative and Anorganic Bovine Bone - a Randomized Controlled Clinical Trial. Completed NCT02102360 Phase 4
23 Periodontal Treatment Response in Type II Diabetic Patients Completed NCT01881074 Phase 4 Triclosan containing toothpaste;Non-triclosan containing toothpaste
24 EMD and/or Bone Substitute for the Treatment of Class II Furcations Completed NCT02474498 Phase 4 EMD
25 Pediatric Study to Access Pharmacokinetics and Safety of Oraqix Gel Completed NCT01591616 Phase 4 lidocaine and prilocaine
26 Efficacy of Two Oral Hygiene Regimens in the Reduction of Dentin Hypersensitivity After Periodontal Treatment Completed NCT02461030 Phase 4 In-office and at home Colgate sensitive pro-relief - CSPR;In-office Villevie® prophy paste + Colgate Toothpaste
27 Locally Delivered Doxycycline Adjunct to Nonsurgical Periodontal Therapy. Completed NCT02487186 Phase 4 Doxicicline
28 Melatonin as an Adjunctive Therapy for Chronic Periodontitis. Completed NCT03368430 Phase 4 Placebo
29 Study on Regenerative Treatment of Intra-bony Defects Completed NCT00757159 Phase 4
30 Long-term Safety of Minocycline in Patients With Gum Disease Completed NCT00668746 Phase 4 Minocycline HCl microspheres
31 Interaction Between Chlorhexidine and Fluoride Completed NCT02935322 Phase 4 0.12 % chlorhexidine + 0.2 % NaF mouthrinse;0.2 % NaF mouthrinse;0.12% chlorhexidine
32 A Clinical Trial to Test the Effect of Experimental Mouth Rinse on Gum Disease Completed NCT02065414 Phase 4
33 A Clinical Trial to Study the Effect of Lycopene in Patients With Gum Disease and type2 Diabetes Mellitus Completed NCT02263352 Phase 4 Lycored soft gels Jagsonpal Pharma, Systemic 8mgms/day
34 Prospective Double-Blind Randomized Controlled Clinical Trial in the Gingivitis Prevention With OPCs Completed NCT02515929 Phase 4
35 Photodynamic Therapy During Supportive Periodontal Therapy Completed NCT02666573 Phase 4
36 Host Modulatory Effects of β-glucan on Localized Aggressive Periodontitis Completed NCT02402296 Phase 4 β-1,3/1,6-D-glucan
37 Effect of Arthrospira Platensis (Spirulina) as an Adjunct to Scaling and Root Planing on Salivary Antioxidant Levels in Chronic Periodontitis Subjects Completed NCT02886676 Phase 4 Spirulina capsules
38 Antimicrobial Therapy as Adjunct to Periodontal Treatment: Effect of Timing Completed NCT02197260 Phase 4 3/d 500 mg metronidazole plus 375 mg amoxicillin for 7 days
39 Impact of Periodontal Treatment on Serum Levels of Hepcidin and Hemoglobin Completed NCT02641210 Phase 4 Albendazole
40 Effects of the Variation in the Time of Systemic Administration of Metronidazole and Amoxicillin Associated to the Non-surgical Therapy of Chronic Periodontitis. Completed NCT01211223 Phase 4 Administration of Metronidazole plus Amoxicillin
41 Effect of Scaling and Root Planing Along With Topical Application of Commercially Available Curcuma Longa Gel on Superoxide Dismutase and Malondialdehyde Levels in Saliva of Chronic Periodontitis Patients Completed NCT02442453 Phase 4 Topical application of curenext gel;Placebo
42 Mechanical-chemical Gingival Therapy in Diabetics and/or Obese Completed NCT02123563 Phase 4
43 Sodium Alendronate in Non Surgical Periodontal Therapy Completed NCT02470611 Phase 4 Sodium alendronate
44 Bacteremia in Periodontal Patients Completed NCT02215473 Phase 4 Chlorhexidine gluconate mouth rinse
45 Treatment of Periodontitis by Conventional 4 Weekly Sections or Within 24 Hours Completed NCT02215460 Phase 4 FMS chlorhexidine rinse;FMS placebo rinse;FMS azithromycin tablets;FMS placebo tablets;QS azithromycin tablets;QS placebo tablets;QS chlorhexidine rinse;QS placebo rinse
46 DFDBA and Xenograft (Cerabone)TM With Decortication in Intrabony Defects Completed NCT02949557 Phase 4
47 MTZ Plus AMX in the Treatment of Smokers and Non-smokers Completed NCT01837199 Phase 4 Metronidazole plus Amoxicillin
48 Regenerative Surgical Treatment of Peri-implantitis Completed NCT02500654 Phase 4
49 Gingival Recession Coverage With and Without Emdogain Completed NCT02230787 Phase 4
50 Simvastatin Gel With Perforated Resorbable Membranes in Treatment of Intrabony Defects in Chronic Periodontitis Completed NCT03419429 Phase 4 Simvastatin

Search NIH Clinical Center for Periodontal Disease

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cochrane evidence based reviews: periodontal diseases

Genetic Tests for Periodontal Disease

Anatomical Context for Periodontal Disease

MalaCards organs/tissues related to Periodontal Disease:

38
Bone, Testes, Kidney, Heart, Neutrophil, Breast, Endothelial

Publications for Periodontal Disease

Articles related to Periodontal Disease:

(show top 50) (show all 1032)
# Title Authors Year
1
Salivary and Serum Antioxidants in Women with Preeclampsia with or Without Periodontal Disease. ( 29391673 )
2018
2
Clinical effect of a dentifrice containing three kinds of bactericidal ingredients on periodontal disease: a pilot study in patients undergoing supportive periodontal therapy. ( 29426362 )
2018
3
Evaluating periodontal disease misclassification mechanisms under partial-mouth recording protocols. ( 29385644 )
2018
4
Effect of a comprehensive plan for periodontal disease care on oral health-related quality of life in patients with periodontal disease in Taiwan. ( 29384859 )
2018
5
Inflammatory and Oxidative Responses in Pregnancies With Obesity and Periodontal Disease. ( 29343164 )
2018
6
Efficacy of local phytotherapy in the nonsurgical treatment of periodontal disease: A systematic review. ( 29352465 )
2018
7
Squamous Cell Carcinoma of the Gingiva Mimicking Periodontal Disease: A Diagnostic Challenge and Therapeutic Dilemma. ( 29447319 )
2018
8
Risk of colorectal cancer in patients with periodontal disease severity: a nationwide, population-based cohort study. ( 29397431 )
2018
9
The immunopathogenic and immunomodulatory effects of interleukin-12 in periodontal disease. ( 29411897 )
2018
10
A cross-sectional study to estimate prevalence of periodontal disease in a population of dogs (Canis familiaris) in commercial breeding facilities in Indiana and Illinois. ( 29346448 )
2018
11
Periodontal Disease Assessed Using Clinical Dental Measurements and Cancer Risk in the ARIC Study. ( 29342298 )
2018
12
Association between interleukin-8 levels and chronic periodontal disease: A PRISMA-compliant systematic review and meta-analysis. ( 28562542 )
2017
13
Periodontal Disease and Incident Cancer Risk among Postmenopausal Women: Results from the Women's Health Initiative Observational Cohort. ( 28765338 )
2017
14
Receiver Operating Characteristic (ROC) Curve-based Prediction Model for Periodontal Disease Updated With the Calibrated Community Periodontal Index. ( 28753099 )
2017
15
Combined antioxidant effects of Neem extract, bacteria, red blood cells and Lysozyme: possible relation to periodontal disease. ( 28797303 )
2017
16
Periodontal disease and risk of non-Hodgkin lymphoma in the Health Professionals Follow-Up Study. ( 27861844 )
2017
17
The relationship between periodontal disease, tooth loss and decreased skeletal bone mineral density in ageing women. ( 28812320 )
2017
18
Knowledge, Attitude, and Awareness among Diabetic Patients in Davangere about the Association between Diabetes and Periodontal Disease. ( 29387625 )
2017
19
Relationship Between Periodontal Disease and Serum Factors in Patients Undergoing Hemodialysis. ( 29399214 )
2017
20
Long-term Hyperglycemia Naturally Induces Dental Caries But Not Periodontal Disease in Type-1 and Type-2 Diabetic Rodents. ( 28793985 )
2017
21
Qualitative and Quantitative Proteome Analysis of Oral Fluids in Health and Periodontal Disease by Mass Spectrometry. ( 27924587 )
2017
22
Genetic susceptibility and periodontal disease: a retrospective study on a large italian sample. ( 28757932 )
2017
23
Prevalence and risk indicators of peri-implantitis in Korean patients with a history of periodontal disease: a cross-sectional study. ( 28861288 )
2017
24
Thermoreversible in situ gel for subgingival delivery of simvastatin for treatment of periodontal disease. ( 28929053 )
2017
25
Association between Periodontal disease and Prostate cancer: Results of a 12-year Longitudinal Cohort Study in South Korea. ( 28928887 )
2017
26
Treatment of experimental periodontal disease by laser therapy in simvastatin-modified rats. ( 28877277 )
2017
27
Association between pro-inflammatory cytokine interleukin-33 and periodontal disease in the elderly: A retrospective study. ( 29386793 )
2017
28
Risk factors of periodontal disease in maintenance hemodialysis patients. ( 28858105 )
2017
29
Association between periodontal disease and mortality in people with CKD: a meta-analysis of cohort studies. ( 28814274 )
2017
30
Serum lipid levels in patients with periodontal disease. A meta-analysis and meta-regression. ( 28782128 )
2017
31
Socioeconomic factors and severity of periodontal disease in adults (35-44 years). A cross sectional study. ( 28936289 )
2017
32
Evaluation of the relationship between obesity, dental caries and periodontal disease in adolescents. ( 29380611 )
2017
33
Impact of Yoga on Periodontal Disease and Stress Management. ( 29422742 )
2017
34
Correlation of ABO Blood Group Phenotype and Rhesus Factor with Periodontal Disease: An Observational Study. ( 28839412 )
2017
35
Neutrophil priming: Implications in periodontal disease. ( 29440782 )
2017
36
Association of periodontal disease with glycemic control in patients with type 2 diabetes in Indian population. ( 28050765 )
2017
37
Inhibition of 5-lipoxygenase attenuates inflammation and BONE resorption in lipopolysaccharide-induced periodontal disease. ( 29381190 )
2017
38
Viruses: Bystanders of periodontal disease. ( 27899307 )
2017
39
Tooth loss, periodontal disease, and dental caries may be associated with decreased oral health-related quality of life, but there is no evidence about the magnitude of this association. ( 28821339 )
2017
40
Inhibition of 5-Lipoxygenase (5-Lo) Attenuates Inflammation and Bone Resorption in Lipopolysaccharide (Lps)-Induced Periodontal Disease. ( 28871891 )
2017
41
Salivary Alkaline Phosphatase as a Noninvasive Marker for Periodontal Disease in Children with Uncontrolled Type 1 Diabetes Mellitus. ( 28052205 )
2017
42
Association Between Asthma and Periodontal Disease: A Systematic Review and Meta-Analysis. ( 28871892 )
2017
43
Immediate implant placement and complete mouth rehabilitation with CAD-CAM titanium frameworks and cemented crowns for a patient with severe periodontal disease: A clinical report. ( 28781070 )
2017
44
Matrix metalloproteinase-8 levels in periodontal disease patients: A systematic review. ( 28898418 )
2017
45
Dental health awareness, attitude, and dental health-care seeking practices as risk indicators for the prevalence of periodontal disease among 15-17-year-old school children in Kozhikode district, Kerala, India. ( 29398860 )
2017
46
What makes a tool appropriate to assess patient-reported outcomes of periodontal disease? ( 29398851 )
2017
47
Does Obstructive Sleep Apnea Increase the Risk for Periodontal Disease?: A Case-control Study. ( 27858556 )
2016
48
Prevalence and risk factors of periodontal disease among pre-conception Chinese women. ( 27903295 )
2016
49
The relationship between recurrent aphthous stomatitis, and periodontal disease and Helicobacter Pylori infection. ( 26733449 )
2016
50
Periodontal Disease and Breast Cancer-Letter. ( 27197139 )
2016

Variations for Periodontal Disease

Expression for Periodontal Disease

Search GEO for disease gene expression data for Periodontal Disease.

Pathways for Periodontal Disease

Pathways related to Periodontal Disease according to GeneCards Suite gene sharing:

(show top 50) (show all 87)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.76 CXCL8 IL17A IL1A IL1B IL6 TIMP1
2
Show member pathways
13.75 CD79A CRP CTSC CXCL8 ELANE GUSB
3
Show member pathways
13.53 CXCL8 IL17A IL1A IL1B IL6 TIMP1
4
Show member pathways
13.43 CXCL8 IL17A IL1A IL1B IL6 MMP1
5
Show member pathways
13.4 CXCL8 IL17A IL1A IL1B IL6 TIMP1
6
Show member pathways
13.09 CXCL8 IL1A IL1B IL6 TLR2 TLR4
7
Show member pathways
12.96 CXCL8 IL17A IL1A IL1B IL6 TNF
8
Show member pathways
12.93 CXCL8 IL1A IL1B IL6 TLR2 TLR4
9
Show member pathways
12.86 ELANE MMP1 MMP2 MMP8 MMP9 TIMP1
10
Show member pathways
12.84 IL1A IL1B IL6 TIMP1 TLR2 TLR4
11
Show member pathways
12.75 IL1A IL1B TLR2 TLR4 TNF TNFRSF11B
12
Show member pathways
12.73 IL17A IL1A IL1B IL6 TLR2 TLR4
13
Show member pathways
12.72 IL17A IL1B IL6 MMP2 TIMP1 TNF
14
Show member pathways
12.7 CXCL8 IL6 MMP9 TLR2 TLR4 TNF
15 12.69 CD79A IL17A IL1B TLR2 TNF TNFSF11
16
Show member pathways
12.66 CXCL8 IL1B IL6 TLR2