MCID: PRD007
MIFTS: 60

Periodontal Disease malady

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Periodontal Disease

Aliases & Descriptions for Periodontal Disease:

Name: Periodontal Disease 12 14
Periodontal Diseases 52 42 69
Disease of Supporting Structures of Teeth, Nos 12
Periodontium Disorder 12
Gingival Diseases 69

Classifications:



External Ids:

Disease Ontology 12 DOID:3388
ICD10 33 K05.6
MeSH 42 D010510
NCIt 47 C63743
UMLS 69 C0031090

Summaries for Periodontal Disease

MalaCards based summary : Periodontal Disease, also known as periodontal diseases, is related to tuberculosis and peripheral vascular disease, and has symptoms including halitosis, snoring and tenderness of gums. An important gene associated with Periodontal Disease is IL1B (Interleukin 1 Beta), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Ethanol and Zinc have been mentioned in the context of this disorder. Affiliated tissues include bone, t cells and neutrophil, and related phenotypes are homeostasis/metabolism and immune system

Wikipedia : 71 Periodontitis, also known as gum disease and pyorrhea, is a set of inflammatory diseases affecting the... more...

Related Diseases for Periodontal Disease

Diseases related to Periodontal Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 421)
id Related Disease Score Top Affiliating Genes
1 tuberculosis 29.7 IL17A IL1B IL6 TNF
2 peripheral vascular disease 29.6 ELANE MMP1 MMP8
3 meningitis 29.4 CXCL8 IL1A IL6 TNF
4 myocardial infarction 29.4 CRP IL1B IL6 MMP2 MMP9 TIMP1
5 osteonecrosis 29.1 CRP CXCL8 IL1B IL6 MMP1 TIMP1
6 rheumatoid arthritis 29.1 CD79A CRP CXCL8 IL17A IL1A IL1B
7 gingivitis 11.4
8 periodontosis 11.4
9 aggressive periodontitis 11.3
10 periodontitis 11.3
11 ehlers-danlos syndrome, type viii 11.0
12 hajdu-cheney syndrome 10.7
13 singleton-merten syndrome 1 10.7
14 aplasia of lacrimal and salivary glands 10.7
15 periodontitis 1, juvenile 10.7
16 dental abscess 10.7
17 necrotizing ulcerative gingivitis 10.7
18 ehlers-danlos syndrome, periodontal type 2 10.7
19 intussusception 10.4 IL1B TNF
20 cerebellar disease 10.4 IL1A IL1B TNF
21 bipolar i disorder 10.4 IL1B IL6 TNF
22 tinea capitis 10.4 IL1B IL6 TNF
23 laryngotracheoesophageal cleft type 2 10.4 CRP IL1B IL6
24 measles 10.4 IL1B IL6 TNF
25 cataract 10.4 CRP IL1B TNF
26 unilateral multicystic dysplastic kidney 10.4 CRP IL6 TNF
27 gastric leiomyoma 10.4 IL1B IL6 TLR4
28 gonococcal endophthalmia 10.4 IL1B IL6 TNF
29 ectodermal dysplasia bartalos type 10.4 IL1B IL6 TNF
30 primary ciliary dyskinesia 10.4 IL1A IL6 TNF
31 mineral metabolism disease 10.4 IL1B IL6 TNF
32 pasteurellosis 10.4 IL6 MMP1 MMP8
33 megaloblastic anemia 10.4 CRP IL1B TLR4
34 migraine with aura 10.4 IL1B IL6 TNF
35 smooth muscle tumor 10.4 IL17A IL1A IL6
36 gastric lymphoma 10.4 CRP IL17A IL6
37 joint disorders 10.4 CRP IL6 TNF
38 inhalation anthrax 10.4 CRP IL17A MMP8
39 bladder signet ring cell adenocarcinoma 10.4 IL1B IL6 TNF
40 spotted fever 10.4 TLR2 TLR4 TNF
41 pyloric stenosis, infantile hypertrophic, 2 10.4 CRP IL1B TNF
42 motility-related diarrhea 10.3 IL1B IL6 TNF
43 clostridium difficile colitis 10.3 CD79A IL6 TNF
44 splenic artery aneurysm 10.3 IL1B IL6 TNF
45 anal paget's disease 10.3 IL1A IL1B IL6 TNF
46 gastroduodenal crohn's disease 10.3 CD79A IL1B TNF
47 hypertensive heart disease 10.3 CRP TLR2 TLR4
48 steroid dehydrogenase deficiency dental anomalies 10.3 IL1A IL1B IL6 TNF
49 aseptic meningitis 10.3 TLR2 TLR4 TNF
50 hereditary night blindness 10.3 IL6 MMP1 TNF

Graphical network of the top 20 diseases related to Periodontal Disease:



Diseases related to Periodontal Disease

Symptoms & Phenotypes for Periodontal Disease

UMLS symptoms related to Periodontal Disease:


halitosis, snoring, tenderness of gums, oral manifestations

MGI Mouse Phenotypes related to Periodontal Disease:

44 (show all 12)
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.41 CD79A CRP CTSC ELANE GUSB IL17A
2 immune system MP:0005387 10.39 CD79A CRP CTSC ELANE IL17A IL1A
3 hematopoietic system MP:0005397 10.38 CD79A CTSC ELANE GUSB IL17A IL1A
4 growth/size/body region MP:0005378 10.27 IL17A IL6 MMP2 MMP9 TIMP1 TLR2
5 cardiovascular system MP:0005385 10.25 CRP IL1A IL1B IL6 MMP2 MMP9
6 mortality/aging MP:0010768 10.13 ELANE GUSB IL17A IL1B IL6 MMP2
7 integument MP:0010771 10.1 CTSC GUSB IL1A IL1B IL6 MMP9
8 neoplasm MP:0002006 10.1 IL6 MMP1 MMP2 MMP8 MMP9 TIMP1
9 limbs/digits/tail MP:0005371 9.91 GUSB MMP9 TIMP1 TLR4 TNF TNFRSF11B
10 renal/urinary system MP:0005367 9.7 TLR4 CD79A GUSB IL17A IL6 MMP9
11 respiratory system MP:0005388 9.61 IL6 MMP2 MMP9 TIMP1 TLR2 TLR4
12 skeleton MP:0005390 9.4 GUSB IL17A IL1B IL6 MMP2 MMP9

Drugs & Therapeutics for Periodontal Disease

Drugs for Periodontal Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 424)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ethanol Approved Phase 4,Phase 3,Phase 2 64-17-5 702
2
Zinc Approved Phase 4,Phase 2,Phase 3 7440-66-6 32051 23994
3
Epinephrine Approved, Vet_approved Phase 4,Phase 2,Phase 1,Early Phase 1 51-43-4 5816
4
Ciprofloxacin Approved, Investigational Phase 4,Phase 1 85721-33-1 2764
5
Acetaminophen Approved Phase 4,Phase 2,Phase 3 103-90-2 1983
6 sodium fluoride Approved Phase 4,Phase 3,Phase 1,Phase 2 7681-49-4
7
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2 22916-47-8 4189
8
Lidocaine Approved, Vet_approved Phase 4,Phase 2,Phase 1,Early Phase 1 137-58-6 3676
9
Levonorgestrel Approved, Investigational Phase 4 797-63-7, 17489-40-6 13109
10
Azithromycin Approved Phase 4,Phase 2 83905-01-5 55185 53477736 447043
11
Amoxicillin Approved, Vet_approved Phase 4,Phase 3,Phase 2 26787-78-0 33613 2171
12
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 564-25-0 54671203
13
Metronidazole Approved Phase 4,Phase 3,Phase 2,Phase 1 443-48-1 4173
14
Chlorhexidine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 55-56-1 9552079 2713
15
Menthol Approved Phase 4,Phase 3,Early Phase 1 2216-51-5 16666
16
Aminocaproic Acid Approved, Investigational Phase 4,Phase 3 60-32-2 564
17
Triclosan Approved Phase 4,Phase 3,Phase 1,Phase 2 3380-34-5 5564
18
Hexetidine Approved Phase 4 141-94-6
19
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
20
Aspirin Approved, Vet_approved Phase 4,Phase 2,Phase 3 50-78-2 2244
21
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757 53477783
22
Montelukast Approved Phase 4 158966-92-8 5281040
23
Ibuprofen Approved Phase 4,Phase 2,Phase 3 15687-27-1 3672
24
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 1,Phase 2 9004-61-9 53477741 24759
25
Alendronate Approved Phase 4,Phase 2,Phase 3 121268-17-5, 66376-36-1 2088
26
Zoledronic acid Approved Phase 4 118072-93-8 68740
27
Thymol Approved Phase 4 89-83-8 6989
28
Norgestimate Approved Phase 4 35189-28-7 6540478
29
Minocycline Approved, Investigational Phase 4,Phase 3,Phase 1 10118-90-8 5281021
30
Clarithromycin Approved Phase 4,Phase 2,Phase 3 81103-11-9 84029
31
Etoricoxib Approved, Investigational Phase 4 202409-33-4 123619
32
Moxifloxacin Approved, Investigational Phase 4 354812-41-2, 151096-09-2 152946
33
Albendazole Approved, Vet_approved Phase 4 54965-21-8 2082
34
Mepivacaine Approved, Vet_approved Phase 4 96-88-8 4062
35
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
36
Prilocaine Approved Phase 4 721-50-6 4906
37
Methyl salicylate Approved, Vet_approved Phase 4 119-36-8 4133
38
Coal tar Approved Phase 4 8007-45-2
39
Penicillin V Approved, Vet_approved Phase 4 87-08-1 6869
40
Vitamin C Approved, Nutraceutical Phase 4,Phase 3 50-81-7 5785 54670067
41
Methylene blue Investigational Phase 4,Phase 2 61-73-4
42 Progestins Phase 4
43 Fluorides Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1
44 Chlorhexidine gluconate Phase 4,Phase 3,Phase 2,Early Phase 1
45
Lactitol Phase 4 585-86-4 3871
46 Risedronate Sodium Phase 4 115436-72-1
47 Analgesics Phase 4,Phase 2,Phase 3,Early Phase 1
48 calcium channel blockers Phase 4
49 Chelating Agents Phase 4
50 Mydriatics Phase 4,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 1032)
id Name Status NCT ID Phase
1 Clinical Investigation of the Effects of Colgate Total Toothpaste as Compared to a Matching Placebo on Periodontal Disease and Systemic Inflammatory Markers Unknown status NCT02670135 Phase 4
2 The Treatment of Periodontal Diseases Unknown status NCT01318928 Phase 4
3 Norplant and Irregular Bleeding/Spotting Unknown status NCT00064766 Phase 4
4 Effect of Actonel on Periodontal Health of Postmenopausal Women Unknown status NCT00594334 Phase 4
5 Evaluation of Photodynamic Treatment FOTOSAN® Efficacy in Periodontology Unknown status NCT02030470 Phase 4
6 Bone Quality and Quantity Following Guided Bone Regeneration Prior to Dental Implant Placement Unknown status NCT01603693 Phase 4
7 Periodontal Therapy in Coronary Artery Patients Unknown status NCT01609725 Phase 4
8 Clinical and Microbiological Effects of an Essential Oils Solution Used as an Adjunct to Daily Oral Hygiene Practices in Chronic Periodontitis Patients in Supportive Care Unknown status NCT01195493 Phase 4
9 Metronidazole and Amoxicillin for the Treatment of Type 2 Diabetic Subjects With Periodontitis Unknown status NCT02135952 Phase 4
10 SRP in Combination With PERIOWAVE in Comparison to SRP Alone in Chronic Periodontitis Unknown status NCT00296881 Phase 4
11 Clinical, Microbiological and Biochemical Effects of the Antimicrobial Photodynamic Therapy Unknown status NCT01532674 Phase 4
12 Study of Scaling and Root Planing With PerioWave Versus Scaling and Root Planing Alone in Chronic Periodontitis Unknown status NCT00297531 Phase 4
13 Methodology Antiseptic Application, Influence on Oral Biofilm. Unknown status NCT02267239 Phase 4
14 Evaluation of a Lateral Window Technique Augmentation for Maxillary Sinus Using Ultrasound Activated Pins Unknown status NCT02449707 Phase 4
15 Connective Tissue Graft Versus Mucograft Collagen Matrix for Coverage of Multiple Gingival Recession Defects Unknown status NCT01440426 Phase 4
16 Platelet Rich Fibrin in the Treatment of Palatal Wounds Unknown status NCT02438046 Phase 4
17 Anticaries Effect of Probiotic Lactobacillus Brevis CD2 (Lb CD2). Unknown status NCT01778699 Phase 4
18 Adhesion of Connective Tissue Around Laser-treated Abutments for Dental Implants - Clinical Trial in Humans Unknown status NCT01954485 Phase 4
19 Evaluation of Platelet Rich Fibrin on Reduction of Periodontal Problems After Surgical Removal of Mandibular Third Molar Unknown status NCT01583491 Phase 4
20 Randomized Clinical Trial With Aminocaproic Acid in the Prevention of Exodontic Bleeding in Anticoagulants Patients Unknown status NCT02238288 Phase 4
21 Relationship of Periodontal Disease Treatment and Type 2 Diabetes Mellitus in the Gullah Population Completed NCT01798225 Phase 4
22 Periodontal Treatment Response in Type II Diabetic Patients Completed NCT01881074 Phase 4
23 Conventional or Minimally Invasive Surgical Technique for the Treatment of Furcation Defects Using Enamel Matrix Derivative and Anorganic Bovine Bone - a Randomized Controlled Clinical Trial. Completed NCT02102360 Phase 4
24 Pediatric Study to Access Pharmacokinetics and Safety of Oraqix Gel Completed NCT01591616 Phase 4
25 EMD and/or Bone Substitute for the Treatment of Class II Furcations Completed NCT02474498 Phase 4
26 Efficacy of Two Oral Hygiene Regimens in the Reduction of Dentin Hypersensitivity After Periodontal Treatment Completed NCT02461030 Phase 4
27 Locally Delivered Doxycycline Adjunct to Nonsurgical Periodontal Therapy. Completed NCT02487186 Phase 4
28 Study on Regenerative Treatment of Intra-bony Defects Completed NCT00757159 Phase 4
29 Long-term Safety of Minocycline in Patients With Gum Disease Completed NCT00668746 Phase 4
30 Interaction Between Chlorhexidine and Fluoride Completed NCT02935322 Phase 4
31 A Clinical Trial to Test the Effect of Experimental Mouth Rinse on Gum Disease Completed NCT02065414 Phase 4
32 A Clinical Trial to Study the Effect of Lycopene in Patients With Gum Disease and type2 Diabetes Mellitus Completed NCT02263352 Phase 4
33 Prospective Double-Blind Randomized Controlled Clinical Trial in the Gingivitis Prevention With OPCs Completed NCT02515929 Phase 4
34 Photodynamic Therapy During Supportive Periodontal Therapy Completed NCT02666573 Phase 4
35 Host Modulatory Effects of β-glucan on Localized Aggressive Periodontitis Completed NCT02402296 Phase 4
36 Antimicrobial Therapy as Adjunct to Periodontal Treatment: Effect of Timing Completed NCT02197260 Phase 4
37 Impact of Periodontal Treatment on Serum Levels of Hepcidin and Hemoglobin Completed NCT02641210 Phase 4
38 Effect of Arthrospira Platensis (Spirulina) as an Adjunct to Scaling and Root Planing on Salivary Antioxidant Levels in Chronic Periodontitis Subjects Completed NCT02886676 Phase 4
39 Effects of the Variation in the Time of Systemic Administration of Metronidazole and Amoxicillin Associated to the Non-surgical Therapy of Chronic Periodontitis. Completed NCT01211223 Phase 4
40 Effect of Scaling and Root Planing Along With Topical Application of Commercially Available Curcuma Longa Gel on Superoxide Dismutase and Malondialdehyde Levels in Saliva of Chronic Periodontitis Patients Completed NCT02442453 Phase 4
41 Mechanical-chemical Gingival Therapy in Diabetics and/or Obese Completed NCT02123563 Phase 4
42 Sodium Alendronate in Non Surgical Periodontal Therapy Completed NCT02470611 Phase 4
43 Bacteremia in Periodontal Patients Completed NCT02215473 Phase 4
44 Treatment of Periodontitis by Conventional 4 Weekly Sections or Within 24 Hours Completed NCT02215460 Phase 4
45 DFDBA and Xenograft (Cerabone)TM With Decortication in Intrabony Defects Completed NCT02949557 Phase 4
46 MTZ Plus AMX in the Treatment of Smokers and Non-smokers Completed NCT01837199 Phase 4
47 Regenerative Surgical Treatment of Peri-implantitis Completed NCT02500654 Phase 4
48 Gingival Recession Coverage With and Without Emdogain Completed NCT02230787 Phase 4
49 Estimation of Interleukin-21 Levels in Gingival Crevicular Fluid in Patients With Periodontal Health and Disease Following Non-surgical Periodontal Therapy: A Clinico-biochemical Study Completed NCT02861937 Phase 4
50 Treatment of Chronic Periodontitis With Repeated Adjunctive Antimicrobial Photodynamic Therapy Completed NCT02734784 Phase 4

Search NIH Clinical Center for Periodontal Disease

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: periodontal diseases

Genetic Tests for Periodontal Disease

Anatomical Context for Periodontal Disease

MalaCards organs/tissues related to Periodontal Disease:

39
Bone, T Cells, Neutrophil, Heart, Kidney, Endothelial, Testes

Publications for Periodontal Disease

Articles related to Periodontal Disease:

(show top 50) (show all 988)
id Title Authors Year
1
Qualitative and Quantitative Proteome Analysis of Oral Fluids in Health and Periodontal Disease by Mass Spectrometry. ( 27924587 )
2017
2
Viruses: Bystanders of periodontal disease. ( 27899307 )
2017
3
Association of periodontal disease with glycemic control in patients with type 2 diabetes in Indian population. ( 28050765 )
2017
4
Periodontal disease and risk of non-Hodgkin lymphoma in the Health Professionals Follow-Up Study. ( 27861844 )
2017
5
Salivary Alkaline Phosphatase as a Noninvasive Marker for Periodontal Disease in Children with Uncontrolled Type 1 Diabetes Mellitus. ( 28052205 )
2017
6
Association between Smoking and Periodontal Disease in Korean Adults: The Fifth Korea National Health and Nutrition Examination Survey (2010 and 2012). ( 27073611 )
2016
7
Formulation and evaluation of hydrogel containing dry extract of Tormentillae rhizoma designed for periodontal disease. ( 27976217 )
2016
8
Handling the Periodontal Disease in Community. ( 27114992 )
2016
9
Identification of biomarkers for periodontal disease using the immunoproteomics approach. ( 27635317 )
2016
10
Number of teeth predict depressive symptoms in a longitudinal study on patients with periodontal disease. ( 27663105 )
2016
11
Role of NOD2 and RIP2 in host-microbe interactions with Gram-negative bacteria: insights from the periodontal disease model. ( 27605548 )
2016
12
Should implants be considered for patients with periodontal disease? ( 27932832 )
2016
13
Salivary and serum inflammatory mediators among pre-conception women with periodontal disease. ( 27978823 )
2016
14
Viral serological and molecular data on possible involvement of herpes viruses in periodontal disease. ( 27916250 )
2016
15
Periodontal disease detection in primary and mixed dentitions. ( 27613405 )
2016
16
Relationship among Periodontal Disease, Insulin Resistance, Salivary Cortisol, and Stress Levels during Pregnancy. ( 27058372 )
2016
17
The Kidney and Periodontal Disease (KAPD) study: A pilot randomized controlled trial testing the effect of non-surgical periodontal therapy on chronic kidney disease. ( 28011387 )
2016
18
Study of the participation of MMP-7, EMMPRIN and cyclophilin A in the pathogenesis of periodontal disease. ( 27597537 )
2016
19
Periodontal Disease and Breast Cancer-Response. ( 27197140 )
2016
20
Lack of association between the TNF-I+-1031genotypes and generalized aggressive periodontitis disease. ( 27755954 )
2016
21
A Systematic Review on the Implication of Minerals in the Onset, Severity and Treatment of Periodontal Disease. ( 27617985 )
2016
22
Trends in Susceptibility to Aggressive Periodontal Disease. ( 28008419 )
2016
23
Cimetidine Reduces Interleukin-6, Matrix Metalloproteinases-1 and -9 Immunoexpression in the Gingival Mucosa of Rat Molars With Induced Periodontal Disease. ( 27587368 )
2016
24
Periodontal disease and inflammatory blood cytokines in patients with stable coronary artery disease. ( 27556206 )
2016
25
Vitamin D Status and Prevalent and Incident Tooth Loss in Postmenopausal Women: The Buffalo Osteoporosis and Periodontal Disease (OsteoPerio) Study. ( 27086615 )
2016
26
Periodontal Disease and Breast Cancer-Letter. ( 27197141 )
2016
27
Comparative molecular analysis of bacterial species associated with periodontal disease. ( 28078876 )
2016
28
Potential Role of Reversion-Inducing Cysteine-Rich Protein with Kazal Motifs (RECK) in Regulation of Matrix Metalloproteinases (MMPs) Expression in Periodontal Diseases. ( 27272560 )
2016
29
A New Multi-Ingredient Recipe for the Treatment of Localized Advanced Periodontal Disease following the Surgical Removal of Impacted Wisdom Teeth. ( 27217960 )
2016
30
Metabolic syndrome as a risk indicator for periodontal disease and tooth loss. ( 27604232 )
2016
31
Prevalence and risk factors of periodontal disease among pre-conception Chinese women. ( 27903295 )
2016
32
Does Obstructive Sleep Apnea Increase the Risk for Periodontal Disease?: A Case-control Study. ( 27858556 )
2016
33
The Prevalence of Canine Oral Protozoa and Their Association with Periodontal Disease. ( 27570233 )
2016
34
Periodontal Disease and Breast Cancer-Letter. ( 27197139 )
2016
35
Periodontal disease and the metabolic syndrome. ( 27861820 )
2016
36
Regulation of the NLRP3 inflammasome in Porphyromonas gingivalis-accelerated periodontal disease. ( 27665233 )
2016
37
Cytokine genotype distribution in patients with periodontal disease and rheumatoid arthritis or diabetes mellitus. ( 27655512 )
2016
38
Clinical and postextraction evaluation of periodontal disease indicators. ( 27143828 )
2016
39
Immunoexpression of HIF-1I+ and VEGF in Periodontal Disease and Healthy Gingival Tissues. ( 27058371 )
2016
40
Periodontal diseases and risk of oral cancer in Southern India: Results from the HeNCe Life study. ( 27215979 )
2016
41
Periodontal Disease and Adverse Pregnancy Outcomes: A Prospective Study in a Low-Risk Population. ( 27208603 )
2016
42
Possible evidence of systemic lupus erythematosus and periodontal disease association mediated by Toll-like receptors 2 and 4. ( 26386242 )
2016
43
Design of a protocol for obtaining genomic DNA from saliva using mouthwash: Samples taken from patients with periodontal disease. ( 27195211 )
2016
44
Correlation of interleukin-6-174 GC and interleukin-6-572 GC gene polymorphisms with periodontal disease in an Iranian population. ( 27605994 )
2016
45
Evaluation of ICAM-1 and VCAM-1 Gene Polymorphisms in Patients with Periodontal Disease. ( 27391418 )
2016
46
VEGF/VEGFR2 Axis in Periodontal Disease Progression and Angiogenesis: Basic Approach for a New Therapeutic Strategy. ( 26709129 )
2016
47
Periodontal Disease and Breast Cancer-Response. ( 27197142 )
2016
48
TCT-158 Treating Periodontal Disease in Patients With ST-Elevation Myocardial Infarction: AA Randomized Clinical Trial. ( 27970326 )
2016
49
A Pilot Study of Active Enzyme Levels in Gingival Crevicular Fluid of Patients with Chronic Periodontal Disease. ( 27106161 )
2016
50
Further evidence for periodontal disease as a risk indicator for adverse pregnancy outcomes. ( 27988930 )
2016

Variations for Periodontal Disease

Expression for Periodontal Disease

Search GEO for disease gene expression data for Periodontal Disease.

Pathways for Periodontal Disease

Pathways related to Periodontal Disease according to GeneCards Suite gene sharing:

(show top 50) (show all 82)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.85 CD79A CRP CTSC CXCL8 ELANE GUSB
2
Show member pathways
13.76 CXCL8 IL17A IL1A IL1B IL6 TIMP1
3
Show member pathways
13.52 CXCL8 IL17A IL1A IL1B IL6 TIMP1
4
Show member pathways
13.44 CXCL8 IL17A IL1A IL1B IL6 MMP1
5
Show member pathways
13.4 CXCL8 IL17A IL1A IL1B IL6 TIMP1
6
Show member pathways
13.1 CXCL8 IL1A IL1B IL6 TLR2 TLR4
7
Show member pathways
13.03 CXCL8 IL1B IL6 MMP9 TLR2 TLR4
8
Show member pathways
12.95 CXCL8 IL17A IL1A IL1B IL6 TNF
9
Show member pathways
12.93 CXCL8 IL1A IL1B IL6 TLR2 TLR4
10
Show member pathways
12.85 ELANE MMP1 MMP2 MMP8 MMP9 TIMP1
11
Show member pathways
12.83 IL1A IL1B IL6 TIMP1 TLR2 TLR4
12 12.75 CXCL8 IL6 MMP1 MMP2 MMP9
13
Show member pathways
12.75 IL1A IL1B TLR2 TLR4 TNF TNFRSF11B
14
Show member pathways
12.73 IL17A IL1A IL1B IL6 TLR2 TLR4
15
Show member pathways
12.71 IL17A IL1B IL6 MMP2 TIMP1 TNF
16 12.67 CD79A IL17A IL1B TLR2 TNF TNFSF11
17
Show member pathways
12.54 IL17A IL1A IL1B IL6 TNF
18 12.42 MMP2 MMP9 TLR2 TLR4 TNF
19
Show member pathways
12.41 CXCL8 IL1A IL6 TLR2 TLR4 TNF
20
Show member pathways
12.41 CXCL8 IL17A IL1B IL6 MMP1 MMP9
21
Show member pathways
12.4 CXCL8 IL1A IL1B IL6 TLR4 TNF
22
Show member pathways
12.39 CRP IL1B IL6 TNF
23
Show member pathways
12.38 IL1A IL1B TLR2 TLR4 TNF
24 12.37 IL1A IL1B IL6 TLR2 TLR4 TNF
25
Show member pathways
12.32 CXCL8 IL1B IL6 TLR2 TLR4 TNF
26 12.31 CXCL8 ELANE IL6 MMP9
27 12.31 CXCL8 IL1A IL1B IL6 TNF
28
Show member pathways
12.3 CXCL8 IL17A IL1A IL1B IL6 TNF
29 12.3 IL6 MMP1 MMP2 MMP9 TLR2 TLR4
30 12.23 IL1A IL1B MMP2 MMP9 TNF
31 12.19 IL1A IL1B TNF TNFRSF11B TNFSF11
32
Show member pathways
12.13 IL1A IL1B TLR2 TLR4
33 12.13 CXCL8 IL1A IL1B IL6 MMP9 TLR4
34
Show member pathways
12.1 IL17A IL1B IL6 TLR2 TLR4