MCID: PRS016
MIFTS: 32

Periosteal Chondrosarcoma malady

Category: Cancer diseases

Aliases & Classifications for Periosteal Chondrosarcoma

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Aliases & Descriptions for Periosteal Chondrosarcoma:

Name: Periosteal Chondrosarcoma 10 12
 
Juxtacortical Chondrosarcoma 65

Classifications:



External Ids:

Disease Ontology10 DOID:5859

Summaries for Periosteal Chondrosarcoma

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MalaCards based summary: Periosteal Chondrosarcoma, also known as juxtacortical chondrosarcoma, is related to osteodysplasia familial anderson type and spinal cord oligodendroglioma. An important gene associated with Periosteal Chondrosarcoma is EXT1 (Exostosin Glycosyltransferase 1), and among its related pathways are DNA damage_ATM/ATR regulation of G1/S checkpoint and FOXM1 transcription factor network. Affiliated tissues include colon, lung and liver, and related mouse phenotypes are limbs/digits/tail and normal.

Related Diseases for Periosteal Chondrosarcoma

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Diseases related to Periosteal Chondrosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 91)
idRelated DiseaseScoreTop Affiliating Genes
1osteodysplasia familial anderson type10.3EXT1, PTHLH
2spinal cord oligodendroglioma10.2IDH1, MDM2
3prion disease10.2CDK4, IDH1
4bronchus adenoma10.2CTNNB1, PTHLH
5fibrosarcoma of bone10.2CDK4, MDM2
6small cell osteogenic sarcoma10.2CDK4, MDM2
7epithelioid sarcoma10.2CDK4, MDM2
8sclerosing liposarcoma10.2CDK4, MDM2
9extrahepatic bile duct lipoma10.2CDK4, MDM2
10pediatric fibrosarcoma10.2CTNNB1, MDM2
11facial injuries and disorders10.1MDM2, RB1
12epidural spinal canal angiolipoma10.1CDK4, MDM2
13agraphia10.1EXT1, IDH1, PTHLH
14hydranencephaly10.1EXT1, IDH1, PTHLH
15breast adenomyoepithelial adenosis10.1IDH1, MDM2
16tendon sheath lipoma10.1CDK4, MDM2
17merrf syndrome10.1CDK4, MDM2
18adult astrocytic tumour10.1IDH1, MDM2
19sebaceous breast carcinoma10.1CDK4, MDM2
20ovarian hyperstimulation syndrome10.1
21coronary artery disease10.1
22myelodysplastic syndrome10.1
23retinoblastoma10.1
24artery disease10.1
25peritoneal mesothelioma10.1
26intracranial hypotension10.1
27basaloid squamous cell carcinoma10.1
28peritonitis10.1
29recurrent respiratory papillomatosis10.1
30malignant peritoneal mesothelioma10.1
31retroperitoneum carcinoma10.1CDK4, MDM2
32anaplastic plasmacytoma10.0CDKN2A, IDH1
33chondroma10.0CTNNB1, EXT1, PTHLH
34melanoma10.0CDK4, MDM2
35trichorhinophalangeal syndrome, type ii10.0CDK4, EXT1, PTHLH
36nezelof syndrome10.0CDK4, EXT1, MDM2
37middle ear squamous cell carcinoma10.0CDKN2A, MDM2
38vitamin d-dependent rickets, type i10.0CDK4, MDM2
39ovary leiomyosarcoma10.0CDKN2A, MDM2
40peripheral osteosarcoma10.0CDK4, MDM2, PTHLH
41vulva verrucous carcinoma9.9CDKN2A, MDM2
42developmental and speech delay due to sox5 deficiency9.9CDKN2A, CTNNB1
43schwannoma of twelfth cranial nerve9.9CDKN2A, MDM2
44giant cell glioblastoma9.9CDK4, IDH1, RB1
45esophageal lipoma9.8CDK4, MDM2, RB1
46classic type lipoma9.8CDK4, MDM2, RB1
47median neuropathy9.8CDK4, MDM2, RB1
48rhabdomyosarcoma 2, alveolar9.8CDK4, MDM2, RB1
49gliomatosis peritonei9.8CDKN2A, IDH1, MDM2
50bone osteosarcoma9.7CDK4, IDH1, MDM2, PTHLH

Graphical network of the top 20 diseases related to Periosteal Chondrosarcoma:



Diseases related to periosteal chondrosarcoma

Symptoms for Periosteal Chondrosarcoma

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Drugs & Therapeutics for Periosteal Chondrosarcoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Periosteal Chondrosarcoma

Genetic Tests for Periosteal Chondrosarcoma

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Anatomical Context for Periosteal Chondrosarcoma

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MalaCards organs/tissues related to Periosteal Chondrosarcoma:

33
Colon, Lung, Liver, Endothelial

Animal Models for Periosteal Chondrosarcoma or affiliated genes

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MGI Mouse Phenotypes related to Periosteal Chondrosarcoma:

38 (show all 25)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053718.5CTNNB1, EXT1, MDM2, PTHLH, RB1
2MP:00028738.4CDK4, CTNNB1, EXT1, MDM2, RB1
3MP:00053828.3CTNNB1, EXT1, MDM2, PTHLH, RB1
4MP:00053888.1CDKN2A, CTNNB1, IDH1, PTHLH, RB1
5MP:00030128.1CDKN2A, CTNNB1, EXT1, MDM2, RB1
6MP:00053708.0CDK4, CDKN2A, CTNNB1, MDM2, RB1
7MP:00011868.0CDK4, CDKN2A, CTNNB1, MDM2, RB1
8MP:00053697.8CDK4, CDKN2A, CTNNB1, MDM2, RB1
9MP:00053807.7CDK4, CDKN2A, CTNNB1, EXT1, MDM2, RB1
10MP:00020067.6CDK4, CDKN2A, CTNNB1, EXT1, MDM2, RB1
11MP:00053917.6CDK4, CDKN2A, CTNNB1, EXT1, PTHLH, RB1
12MP:00053797.6CDK4, CDKN2A, CTNNB1, MDM2, PTHLH, RB1
13MP:00053897.5CDK4, CDKN2A, CTNNB1, MDM2, PTHLH, RB1
14MP:00107717.2CDK4, CDKN2A, CTNNB1, EXT1, MDM2, PTHLH
15MP:00053867.1CDK4, CDKN2A, CTNNB1, EXT1, MDM2, PTHLH
16MP:00053857.1CDK4, CDKN2A, CTNNB1, MDM2, PTHLH, RB1
17MP:00053817.1CDK4, CDKN2A, CTNNB1, EXT1, MDM2, PTHLH
18MP:00036317.1CDK4, CDKN2A, CTNNB1, EXT1, MDM2, PTHLH
19MP:00053847.1CDK4, CDKN2A, CTNNB1, EXT1, MDM2, PTHLH
20MP:00053767.0CDK4, CDKN2A, CTNNB1, IDH1, MDM2, PTHLH
21MP:00053906.9CDKN2A, CTNNB1, EXT1, IDH1, MDM2, PTHLH
22MP:00053876.6CDK4, CDKN2A, CTNNB1, IDH1, MDM2, PTHLH
23MP:00107686.6CDK4, CDKN2A, CTNNB1, EXT1, IDH1, MDM2
24MP:00053786.5CDK4, CDKN2A, CTNNB1, EXT1, IDH1, MDM2
25MP:00053976.4CDK4, CDKN2A, CTNNB1, IDH1, MDM2, PTHLH

Publications for Periosteal Chondrosarcoma

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Articles related to Periosteal Chondrosarcoma:

(show all 20)
idTitleAuthorsYear
1
Once Daily Dosing of Ceftriaxone and Metronidazole in Children With Perforated Appendicitis. (27199621)
2016
2
Glycomimetic-based pharmacological chaperones for lysosomal storage disorders: lessons from Gaucher, GM1-gangliosidosis and Fabry diseases. (27043200)
2016
3
Standards of yellow fever vaccination and travel medicine practice in the Republic of Ireland: A questionnaire-based evaluation. (26148651)
2015
4
Is hyperuricemia a risk factor for arteriosclerosis? Uric acid and arteriosclerosis in apolipoprotein e-deficient mice. (25451835)
2014
5
Keratoacanthoma Clinical Behavior: A Systematic Review. (24366198)
2013
6
Stathmin expression in glioma-derived microvascular endothelial cells: a novel therapeutic target. (22038457)
2012
7
Richter's syndrome in colon: case report. (21057893)
2012
8
An unusual case of monosomy 18p: minor malformations with speech delay. (16052867)
2005
9
A uterine fibroid presenting as an incarcerated umbilical hernia during pregnancy. (16007370)
2005
10
Vascular effects of simvastatin combined with ramipril in hypercholesterolemic patients with coronary artery disease, compared with simvastatin alone: a randomized, double-blind, placebo-controlled, crossover study. (15488877)
2004
11
Targeted therapy in combination with gemcitabine in non-small cell lung cancer. (12917817)
2003
12
Persistent expression of canine factor IX in hemophilia B canines. (10516718)
1999
13
Abnormalities in the ATM gene effectively contribute to the occurrence of thymic lymphomas in patients with ataxia telangiectasia]. (10507849)
1999
14
The Heidenhain variant of Creutzfeldt-Jakob disease. (9923761)
1999
15
Long-term survival after continuous infusion interleukin-2. (10851471)
1997
16
Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation. (8665852)
1996
17
An in vivo comparison of oral 5-iodo-2'-deoxyuridine and 5-iodo-2-pyrimidinone-2'-deoxyribose toxicity, pharmacokinetics, and DNA incorporation in athymic mouse tissues and the human colon cancer xenograft, HCT-116. (8168099)
1994
18
The gastric mucosa in experimental duodenogastric reflux. A scanning electron microscope study. (6588499)
1984
19
Bilateral nephroblastomatosis and Klippel Trenaunay syndrome. (4362958)
1974
20
Liver disease associated with secondary syphilis. (4931102)
1971

Variations for Periosteal Chondrosarcoma

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Expression for genes affiliated with Periosteal Chondrosarcoma

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Search GEO for disease gene expression data for Periosteal Chondrosarcoma.

Pathways for genes affiliated with Periosteal Chondrosarcoma

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Pathways related to Periosteal Chondrosarcoma according to GeneCards Suite gene sharing:

(show all 32)
idSuper pathwaysScoreTop Affiliating Genes
19.5CDK4, MDM2
29.3CDK4, RB1
39.3CTNNB1, RB1
4
Show member pathways
9.2CDKN2A, MDM2
59.0CDK4, CTNNB1, MDM2
6
Show member pathways
8.9CDK4, MDM2, RB1
78.9CDK4, MDM2, RB1
8
Show member pathways
8.9CDK4, MDM2, RB1
9
Show member pathways
8.9CDK4, MDM2, RB1
108.9CTNNB1, MDM2, RB1
118.8CDK4, CTNNB1, RB1
12
Show member pathways
8.8CDK4, CTNNB1, RB1
13
Show member pathways
8.7CDK4, CTNNB1, RB1
148.7CDK4, CDKN2A, MDM2
15
Show member pathways
8.7CDK4, CDKN2A, MDM2
168.6CDKN2A, MDM2, RB1
178.6CDKN2A, MDM2, RB1
18
Show member pathways
8.5CDK4, CDKN2A, RB1
19
Show member pathways
8.5CDK4, CDKN2A, RB1
208.4CDK4, CTNNB1, MDM2, RB1
21
Show member pathways
8.1CDK4, CDKN2A, MDM2, RB1
228.1CDK4, CDKN2A, MDM2, RB1
23
Show member pathways
8.1CDK4, CDKN2A, MDM2, RB1
24
Show member pathways
8.1CDK4, CDKN2A, MDM2, RB1
258.1CDK4, CDKN2A, MDM2, RB1
268.1CDK4, CDKN2A, MDM2, RB1
27
Show member pathways
8.1CDK4, CDKN2A, MDM2, RB1
288.1CDKN2A, CTNNB1, MDM2, RB1
298.0CDK4, CDKN2A, CTNNB1, RB1
30
Show member pathways
7.5CDK4, CDKN2A, CTNNB1, MDM2, RB1
317.5CDK4, CDKN2A, CTNNB1, MDM2, RB1
327.5CDK4, CDKN2A, CTNNB1, MDM2, RB1

GO Terms for genes affiliated with Periosteal Chondrosarcoma

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Biological processes related to Periosteal Chondrosarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1myoblast differentiationGO:00454459.7CTNNB1, RB1
2response to toxic substanceGO:00096369.5CDK4, MDM2
3androgen receptor signaling pathwayGO:00305219.5CTNNB1, RB1
4regulation of gene expressionGO:00104689.2CDK4, CTNNB1, PTHLH
5positive regulation of cell proliferationGO:00082849.0CDK4, MDM2, PTHLH

Sources for Periosteal Chondrosarcoma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet