MCID: PRS016
MIFTS: 35

Periosteal Chondrosarcoma malady

Category: Cancer diseases

Aliases & Classifications for Periosteal Chondrosarcoma

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Aliases & Descriptions for Periosteal Chondrosarcoma:

Name: Periosteal Chondrosarcoma 10 12
 
Juxtacortical Chondrosarcoma 65

Classifications:



External Ids:

Disease Ontology10 DOID:5859

Summaries for Periosteal Chondrosarcoma

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MalaCards based summary: Periosteal Chondrosarcoma, also known as juxtacortical chondrosarcoma, is related to chondroma and chondrosarcoma, and has symptoms including pain An important gene associated with Periosteal Chondrosarcoma is EXT1 (Exostosin Glycosyltransferase 1), and among its related pathways are DNA damage_ATM/ATR regulation of G1/S checkpoint and FOXM1 transcription factor network. Affiliated tissues include lung, bone and breast, and related mouse phenotypes are limbs/digits/tail and normal.

Related Diseases for Periosteal Chondrosarcoma

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Diseases related to Periosteal Chondrosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 83)
idRelated DiseaseScoreTop Affiliating Genes
1chondroma29.9CTNNB1, EXT1, PTHLH
2chondrosarcoma10.5
3periostitis10.5
4osteodysplasia familial anderson type10.4EXT1, PTHLH
5spinal cord oligodendroglioma10.3IDH1, MDM2
6prion disease10.3CDK4, IDH1
7bronchus adenoma10.3CTNNB1, PTHLH
8fibrosarcoma of bone10.3CDK4, MDM2
9small cell osteogenic sarcoma10.3CDK4, MDM2
10epithelioid sarcoma10.3CDK4, MDM2
11sclerosing liposarcoma10.2CDK4, MDM2
12extrahepatic bile duct lipoma10.2CDK4, MDM2
13pediatric fibrosarcoma10.2CTNNB1, MDM2
14facial injuries and disorders10.2MDM2, RB1
15epidural spinal canal angiolipoma10.2CDK4, MDM2
16agraphia10.2EXT1, IDH1, PTHLH
17hydranencephaly10.2EXT1, IDH1, PTHLH
18breast adenomyoepithelial adenosis10.2IDH1, MDM2
19tendon sheath lipoma10.2CDK4, MDM2
20merrf syndrome10.1CDK4, MDM2
21adult astrocytic tumour10.1IDH1, MDM2
22sebaceous breast carcinoma10.1CDK4, MDM2
23retroperitoneum carcinoma10.1CDK4, MDM2
24anaplastic plasmacytoma10.1CDKN2A, IDH1
25melanoma10.1CDK4, MDM2
26trichorhinophalangeal syndrome, type ii10.0CDK4, EXT1, PTHLH
27nezelof syndrome10.0CDK4, EXT1, MDM2
28middle ear squamous cell carcinoma10.0CDKN2A, MDM2
29vitamin d-dependent rickets, type i10.0CDK4, MDM2
30ovary leiomyosarcoma9.9CDKN2A, MDM2
31peripheral osteosarcoma9.9CDK4, MDM2, PTHLH
32enchondroma9.9
33vulva verrucous carcinoma9.9CDKN2A, MDM2
34developmental and speech delay due to sox5 deficiency9.9CDKN2A, CTNNB1
35schwannoma of twelfth cranial nerve9.8CDKN2A, MDM2
36giant cell glioblastoma9.8CDK4, IDH1, RB1
37esophageal lipoma9.8CDK4, MDM2, RB1
38classic type lipoma9.7CDK4, MDM2, RB1
39median neuropathy9.7CDK4, MDM2, RB1
40rhabdomyosarcoma 2, alveolar9.7CDK4, MDM2, RB1
41gliomatosis peritonei9.6CDKN2A, IDH1, MDM2
42bone osteosarcoma9.6CDK4, IDH1, MDM2, PTHLH
43brachyolmia9.6CDKN2A, CTNNB1, IDH1
44pleomorphic xanthoastrocytoma9.6CDK4, CDKN2A, IDH1
45angiolipoma9.6CDK4, CDKN2A, MDM2
46mixed liposarcoma9.6CDK4, CDKN2A, MDM2
47visual cortex disease9.5CDK4, CDKN2A, MDM2
48vasculitis9.5CDKN2A, CTNNB1
49juvenile astrocytoma9.5CDK4, CDKN2A, MDM2
50mononeuritis of upper limb9.5EXT1, MDM2, PTHLH, RB1

Graphical network of the top 20 diseases related to Periosteal Chondrosarcoma:



Diseases related to periosteal chondrosarcoma

Symptoms for Periosteal Chondrosarcoma

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UMLS symptoms related to Periosteal Chondrosarcoma:


pain

Drugs & Therapeutics for Periosteal Chondrosarcoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Periosteal Chondrosarcoma

Genetic Tests for Periosteal Chondrosarcoma

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Anatomical Context for Periosteal Chondrosarcoma

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MalaCards organs/tissues related to Periosteal Chondrosarcoma:

33
Lung, Bone, Breast, Prostate, Colon, Endothelial, B cells

Animal Models for Periosteal Chondrosarcoma or affiliated genes

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MGI Mouse Phenotypes related to Periosteal Chondrosarcoma:

38 (show all 25)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053718.5CTNNB1, EXT1, MDM2, PTHLH, RB1
2MP:00028738.4CDK4, CTNNB1, EXT1, MDM2, RB1
3MP:00053828.3CTNNB1, EXT1, MDM2, PTHLH, RB1
4MP:00053888.1CDKN2A, CTNNB1, IDH1, PTHLH, RB1
5MP:00030128.1CDKN2A, CTNNB1, EXT1, MDM2, RB1
6MP:00053708.0CDK4, CDKN2A, CTNNB1, MDM2, RB1
7MP:00011868.0CDK4, CDKN2A, CTNNB1, MDM2, RB1
8MP:00053697.8CDK4, CDKN2A, CTNNB1, MDM2, RB1
9MP:00053807.7CDK4, CDKN2A, CTNNB1, EXT1, MDM2, RB1
10MP:00020067.6CDK4, CDKN2A, CTNNB1, EXT1, MDM2, RB1
11MP:00053917.6CDK4, CDKN2A, CTNNB1, EXT1, PTHLH, RB1
12MP:00053797.6CDK4, CDKN2A, CTNNB1, MDM2, PTHLH, RB1
13MP:00053897.5CDK4, CDKN2A, CTNNB1, MDM2, PTHLH, RB1
14MP:00107717.2CDK4, CDKN2A, CTNNB1, EXT1, MDM2, PTHLH
15MP:00053867.1CDK4, CDKN2A, CTNNB1, EXT1, MDM2, PTHLH
16MP:00053857.1CDK4, CDKN2A, CTNNB1, MDM2, PTHLH, RB1
17MP:00053817.1CDK4, CDKN2A, CTNNB1, EXT1, MDM2, PTHLH
18MP:00036317.1CDK4, CDKN2A, CTNNB1, EXT1, MDM2, PTHLH
19MP:00053847.1CDK4, CDKN2A, CTNNB1, EXT1, MDM2, PTHLH
20MP:00053767.0CDK4, CDKN2A, CTNNB1, IDH1, MDM2, PTHLH
21MP:00053906.9CDKN2A, CTNNB1, EXT1, IDH1, MDM2, PTHLH
22MP:00053876.6CDK4, CDKN2A, CTNNB1, IDH1, MDM2, PTHLH
23MP:00107686.6CDK4, CDKN2A, CTNNB1, EXT1, IDH1, MDM2
24MP:00053786.5CDK4, CDKN2A, CTNNB1, EXT1, IDH1, MDM2
25MP:00053976.4CDK4, CDKN2A, CTNNB1, IDH1, MDM2, PTHLH

Publications for Periosteal Chondrosarcoma

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Articles related to Periosteal Chondrosarcoma:

(show all 20)
idTitleAuthorsYear
1
Periosteal chondrosarcoma: a histopathological and molecular analysis of a rare chondrosarcoma subtype. (25648524)
2015
2
Bony metastases following complete resection of periosteal chondrosarcoma. (25889026)
2015
3
Usefulness of PET/CT for diagnosis of periosteal chondrosarcoma of the femur: A case report. (24932240)
2014
4
The presentation, treatment and outcome of periosteal chondrosarcoma in the Netherlands. (24891585)
2014
5
IDH1 mutations are not found in cartilaginous tumours other than central and periosteal chondrosarcomas and enchondromas. (22074484)
2012
6
Periosteal chondrosarcoma of metacarpal bone: Report of a rare entity. (23289049)
2012
7
Periosteal chondrosarcoma of the foot: a case report. (20576447)
2010
8
Periosteal chondrosarcoma. (19098166)
2009
9
Periosteal chondrosarcoma with microscopic cortical invasion. (18696199)
2008
10
Survivorship analysis in patients with periosteal chondrosarcoma. (16826117)
2006
11
Periosteal chondrosarcoma in a 9-year-old girl with osteochondromatosis. (15723209)
2005
12
Periosteal chondrosarcoma. (12938935)
2003
13
Periosteal chondrosarcoma. (12195911)
2002
14
DNA ploidy alterations detected during dedifferentiation of periosteal chondrosarcoma. (10472345)
1999
15
Periosteal chondrosarcoma invading the medullary cavity. (9229422)
1997
16
Periosteal chondrosarcoma: a case report and review of the literature. (9111097)
1997
17
Juxtacortical dedifferentiated chondrosarcoma from a primary periosteal chondrosarcoma. (8685228)
1996
18
MR appearance of periosteal chondrosarcoma of the foot. (7822524)
1995
19
Periosteal chondroma and periosteal chondrosarcoma. (4051099)
1985
20
Periosteal chondrosarcoma and periosteal osteosarcoma. Two distinct entities. (7096408)
1982

Variations for Periosteal Chondrosarcoma

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Expression for genes affiliated with Periosteal Chondrosarcoma

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Search GEO for disease gene expression data for Periosteal Chondrosarcoma.

Pathways for genes affiliated with Periosteal Chondrosarcoma

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Pathways related to Periosteal Chondrosarcoma according to GeneCards Suite gene sharing:

(show all 32)
idSuper pathwaysScoreTop Affiliating Genes
19.5CDK4, MDM2
29.3CDK4, RB1
39.3CTNNB1, RB1
4
Show member pathways
9.2CDKN2A, MDM2
59.0CDK4, CTNNB1, MDM2
6
Show member pathways
8.9CDK4, MDM2, RB1
78.9CDK4, MDM2, RB1
8
Show member pathways
8.9CDK4, MDM2, RB1
9
Show member pathways
8.9CDK4, MDM2, RB1
108.9CTNNB1, MDM2, RB1
118.8CDK4, CTNNB1, RB1
12
Show member pathways
8.8CDK4, CTNNB1, RB1
13
Show member pathways
8.7CDK4, CDKN2A, MDM2
148.7CDK4, CDKN2A, MDM2
15
Show member pathways
8.7CDKN2A, CTNNB1, MDM2
168.6CDKN2A, MDM2, RB1
178.6CDKN2A, MDM2, RB1
18
Show member pathways
8.5CDK4, CDKN2A, RB1
19
Show member pathways
8.5CDK4, CDKN2A, RB1
208.4CDK4, CTNNB1, MDM2, RB1
21
Show member pathways
8.1CDK4, CDKN2A, MDM2, RB1
228.1CDK4, CDKN2A, MDM2, RB1
23
Show member pathways
8.1CDK4, CDKN2A, MDM2, RB1
24
Show member pathways
8.1CDK4, CDKN2A, MDM2, RB1
258.1CDK4, CDKN2A, MDM2, RB1
268.1CDK4, CDKN2A, MDM2, RB1
27
Show member pathways
8.1CDK4, CDKN2A, MDM2, RB1
288.1CDKN2A, CTNNB1, MDM2, RB1
298.0CDK4, CDKN2A, CTNNB1, RB1
30
Show member pathways
7.5CDK4, CDKN2A, CTNNB1, MDM2, RB1
317.5CDK4, CDKN2A, CTNNB1, MDM2, RB1
327.5CDK4, CDKN2A, CTNNB1, MDM2, RB1

GO Terms for genes affiliated with Periosteal Chondrosarcoma

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Biological processes related to Periosteal Chondrosarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1myoblast differentiationGO:00454459.7CTNNB1, RB1
2response to toxic substanceGO:00096369.5CDK4, MDM2
3androgen receptor signaling pathwayGO:00305219.5CTNNB1, RB1
4regulation of gene expressionGO:00104689.2CDK4, CTNNB1, PTHLH
5positive regulation of cell proliferationGO:00082849.0CDK4, MDM2, PTHLH

Sources for Periosteal Chondrosarcoma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet