MCID: PRS037
MIFTS: 44

Periostitis malady

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Summaries for Periostitis

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Wikipedia:65 Periostitis, also known as periostalgia, is a medical condition caused by inflammation of the... more...

MalaCards based summary: Periostitis is related to osteitis fibrosa and gingivitis. An important gene associated with Periostitis is TNFRSF11A (tumor necrosis factor receptor superfamily, member 11a, NFKB activator), and among its related pathways are Apoptosis and survival Anti apoptotic TNFs NF kB Bcl 2 pathway and TRAF Pathway. The compounds denosumab and polyethylene have been mentioned in the context of this disorder. Affiliated tissues include bone, lung and endothelial, and related mouse phenotypes are hematopoietic system and skeleton.

Aliases & Classifications for Periostitis

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Related Diseases for Periostitis

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Diseases related to Periostitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 170)
idRelated DiseaseScoreTop Affiliating Genes
1osteitis fibrosa30.6ALPP
2gingivitis30.4TNFRSF11B, ALPP
3osteosclerosis30.3TNFRSF11B, ALPP
4periodontitis30.0IL1RN, TNFRSF11B
5renal osteodystrophy30.0TNFRSF11B, ALPP
6inflammatory bowel disease29.9IL1RN, ALPP
7colitis29.9IL1RN, IL11
8arthritis29.9TNFRSF11A, TNFRSF11B, IL1RN, ALPP
9sarcoidosis29.9ALPP, IL1RN
10osteosarcoma29.7TNFRSF11B, IL1RN, IL11, TNFRSF11A, ALPP
11thrombocytopenia29.6IL11, ALPP
12osteoarthritis29.6TNFRSF11B, IL1RN, TNFRSF11A
13hypercalcemia29.6TNFRSF11B, ALPP, TNFRSF11A
14rheumatoid arthritis29.5TNFRSF11B, IL11, IL1RN, TNFRSF11A
15secondary syphilis29.5ALPP, IL11, TNFRSF11B, TNFRSF11A
16periodontal disease28.9TNFRSF11A, TNFRSF11B, IL11, IL1RN, ALPP
17chondroma10.8
18chondrosarcoma10.6
19periosteal chondrosarcoma10.5
20osteomyelitis10.5
21osteoblastoma10.4
22periosteal osteogenic sarcoma10.3
23syphilis10.3
24alveolar periostitis10.3
25sarcoma10.3
26paget's disease of bone10.2TNFRSF11A, SQSTM1
27juxtacortical chondroma10.2
28polyarteritis nodosa10.2
29typhoid fever10.2
30orbital periostitis10.2
31hyperostosis10.2
32myositis10.2
33neutropenia10.1IL11, IL1RN
34leukopenia10.1ALPP, IL11
35crohn's disease10.1
36gingival recession10.1
37osteochondritis dissecans10.1
38osteonecrosis10.1
39cervicitis10.1
40congenital syphilis10.1
41fasciitis10.1
42keratitis10.1
43vasculitis10.1
44enchondroma10.1
45endotheliitis10.1
46paget disease, juvenile10.1TNFRSF11A, TNFRSF11B
47giant cell tumor10.1TNFRSF11B, TNFRSF11A
48osteopetrosis10.1TNFRSF11B, TNFRSF11A
49pancreatitis10.1ALPP, IL11
50hypersensitivity reaction type ii disease10.1IL1RN, ALPP

Graphical network of the top 20 diseases related to Periostitis:



Diseases related to periostitis

Symptoms for Periostitis

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Drugs & Therapeutics for Periostitis

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Drug clinical trials:

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Search NIH Clinical Center for Periostitis

Genetic Tests for Periostitis

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Anatomical Context for Periostitis

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MalaCards organs/tissues related to Periostitis:

32
Bone, Lung, Endothelial, Heart, Testes, Bone marrow, Brain, Liver

Animal Models for Periostitis or affiliated genes

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MGI Mouse Phenotypes related to Periostitis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053978.5SQSTM1, IL1RN, TNFRSF11B, TNFRSF11A
2MP:00053908.4TNFRSF11A, TNFRSF11B, IL1RN, SQSTM1
3MP:00053787.9SQSTM1, ALPP, IL1RN, TNFRSF11B, TNFRSF11A
4MP:00107687.6TNFRSF11A, TNFRSF11B, IL1RN, ALPP, SQSTM1

Publications for Periostitis

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Articles related to Periostitis:

(show top 50)    (show all 414)
idTitleAuthorsYear
1
Usefulness of PET/CT for diagnosis of periosteal chondrosarcoma of the femur: A case report. (24932240)
2014
2
Plasma fluoride level as a predictor of voriconazole-induced periostitis in patients with skeletal pain. (24992954)
2014
3
High-concentration of BMP2 reduces cell proliferation and increases apoptosis via DKK1 and SOST in human primary periosteal cells. (23360788)
2013
4
Oral medicine case book 45. Periosteal osteosarcoma of the mandible. (23957106)
2012
5
Florid-reactive periostitis of the phalanges: a 2-case report. (22327452)
2012
6
Periosteal Flap fixation of the Globe for Surgical Treatment of Severe Restrictive Strabismus: A Report of Eight Cases with Outcomes. (22204549)
2011
7
Platelet-derived growth factor-BB release profile in gingival crevicular fluid after use of marginal periosteal pedicle graft as an autogenous guided tissue membrane to treat localized intrabony defects. (20681813)
2011
8
Periosteal chondroma of the pediatric cervical spine. (19278317)
2009
9
Syphilitic periostitis. (19393487)
2009
10
Survivorship analysis in patients with periosteal chondrosarcoma. (16826117)
2006
11
Concurrent periosteal chondroma and enchondroma of the fibula mimicking chondrosarcoma. (16421751)
2006
12
A rare case of periosteal osteoblastoma located in the frontal cranial bone. (15913430)
2005
13
In vitro osteogenic differentiation and in vivo bone-forming capacity of human isogenic jaw periosteal cells and bone marrow stromal cells. (16327496)
2005
14
FGF-2 enhances TGF-beta1-induced periosteal chondrogenesis. (15304287)
2004
15
Repair of full-thickness cartilage defects in rabbit knees with free periosteal graft preincubated with transforming growth factor. (12722910)
2003
16
Periosteal hyperostosis (exostosis) in DBA/1 male mice. (12051556)
2002
17
Prevention of postoperative meatal stenosis with anteriorly and inferiorly based periosteal flaps in congenital aural atresia surgery. (11773841)
2002
18
Periosteal chondroma presenting as a subcutaneous mass in the thumb. (11733159)
2001
19
Isolation of a cDNA sequence of rabbit GDF5 (mature form) and pattern of its mRNA expression during periosteal chondrogenesis. (11252805)
2000
20
Florid reactive periostitis ossificans of the proximal aspect of the tibia: a lesion that must be distinguished from osteosarcoma. A case report. (10428133)
1999
21
Gross periostitis ossificans in mandibular osteomyelitis. Review of the English literature and radiographic variation. (9768431)
1998
22
Traumatic ossifying periostitis of the ulna masquerading as a malignancy in a football player. A case report and literature review. (8947411)
1996
23
Musculoskeletal case of the day. Periosteal (juxtacortical) chondroma. (7785598)
1995
24
Mechanical loading stimulates rapid changes in periosteal gene expression. (7895187)
1994
25
Scintigraphic diagnosis of costal periostitis in actinomycosis. (1638850)
1992
26
Iliac periosteal graft with vascular pedicle in the treatment of avascular necrosis of the femoral head. Experimental study and clinical application. (1291204)
1992
27
Effect of lipopolysaccharide from Porphyromonas gingivalis on prostaglandin E2 and interleukin-1-beta release from rat periosteal and human gingival fibroblasts in vitro. (1668251)
1991
28
Cranial fasciitis of childhood with reactive periostitis. (2305359)
1990
29
Massive florid reactive periostitis. (2191267)
1990
30
Bizarre parosteal osteochondromatous proliferation vs. benign florid reactive periostitis. (3492900)
1987
31
Periosteal chondroma: a review of the literature and case report. (3512684)
1986
32
Florid reactive periostitis of the proximal phalanx. Case report. (4019546)
1985
33
Periostitis and osteitis associated with hyaline bodies. (2413879)
1985
34
Pain and periostitis. (4045899)
1985
35
Periosteal chondroma: another cause of carpal tunnel syndrome. (6721390)
1984
36
Periosteal chondroma. A review of twenty cases. (6822582)
1983
37
Ossifying granulomatous periostitis in the course of erythema nodosum. (753821)
1978
38
Cellulitis with underlying inflammatory periostitis of the mandible. (5769294)
1969
39
Periostitis: an early diagnostic sign of juvenile rheumatoid arthritis. (6022368)
1967
40
Electron microscopic study of periosteal hyperostosis in rats with lathyrism induced by aminoacetonitrile. (5234345)
1966
41
PERIOSTITIS OSSIFICANS; ETIOLOGY OF FORMATION AND REPORT OF A CASE. (14176596)
1964
42
Chronic polyostotic periostitis of unknown etiology. (14036714)
1961
43
Pulmonary hypertrophic osteoarthropathy (periostitis); its absence in pulmonary tuberculosis. (13552924)
1958
44
Periostitis of the os calcis; an osteoperiosteal manifestation of rheumatoid arthritis. (18856913)
1948
45
Periostitis. ? Cause. (19988280)
1931
46
Osteo-periostitis of Upper End of Femur. (19978339)
1914
47
Acute Periostitis of Rib with Separation of Sequestra (Non-tuberculous, Non-traumatic). (19975692)
1912
48
Acute Infectious Osteomyelitis and Periostitis. (17857400)
1889
49
Periostitis in Typhoid Fever. (20751254)
1885
50
Vitamin-C Deficiency and Periostitis of Both UlnA (20916142)
.? Scurvy.

Variations for Periostitis

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Expression for genes affiliated with Periostitis

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Expression patterns in normal tissues for genes affiliated with Periostitis

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Pathways for genes affiliated with Periostitis

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Pathways related to Periostitis according to GeneCards/GeneDecks:

(show all 12)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Apoptosis and survival Anti apoptotic TNFs NF kB IAP pathway60
9.6SQSTM1, TNFRSF11A
2
Show member pathways
9.5TNFRSF11B, TNFRSF11A
3
Show member pathways
9.5TNFRSF11B, TNFRSF11A
49.5TNFRSF11A, TNFRSF11B
59.5TNFRSF11A, TNFRSF11B
6
Show member pathways
Prolactin Signaling Pathway37
Development Prolactin receptor signaling60
Leptin signaling pathway37
9.4IL1RN, TNFRSF11A
7
Show member pathways
9.4IL1RN, SQSTM1
8
Show member pathways
IL-1 Signaling Pathway37
IL1-mediated signaling events37
9.4SQSTM1, IL1RN
99.2IL11, TNFRSF11A
10
Show member pathways
RANKL/RANK Signaling Pathway37
Apoptosis and survival APRIL and BAFF signaling60
9.1SQSTM1, TNFRSF11B, TNFRSF11A
119.1SQSTM1, TNFRSF11B, TNFRSF11A
12
Show member pathways
8.7IL11, TNFRSF11B, TNFRSF11A

Compounds for genes affiliated with Periostitis

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Compounds related to Periostitis according to GeneCards/GeneDecks:

(show top 50)    (show all 76)
idCompoundScoreTop Affiliating Genes
1denosumab44 1110.9TNFRSF11A, TNFRSF11B
2polyethylene449.9TNFRSF11A, TNFRSF11B
3etidronate449.8TNFRSF11B, ALPP
4vitamin k2449.8TNFRSF11B, ALPP
5pamidronate44 50 1111.7ALPP, TNFRSF11B
6risedronate44 50 28 61 1113.7ALPP, TNFRSF11B
7anakinra44 1110.7IL1RN, TNFRSF11B
8pmma449.5ALPP, TNFRSF11B
9pyridinoline449.5TNFRSF11B, ALPP
10zoledronic acid449.4ALPP, TNFRSF11B
11filgrastim44 1110.3IL1RN, IL11
12prednisolone44 28 1111.2ALPP, TNFRSF11B, IL1RN
13atorvastatin44 50 28 24 1113.2ALPP, IL1RN, TNFRSF11B
14hydrocortisone44 2 61 1112.2IL1RN, TNFRSF11B, ALPP
15gp 130449.1TNFRSF11A, IL11, TNFRSF11B
16titanium449.0TNFRSF11B, IL11, ALPP
17deoxypyridinoline449.0IL11, TNFRSF11B, ALPP
18alendronate44 50 1111.0ALPP, IL11, TNFRSF11B
19polymyxin b449.0IL1RN, TNFRSF11B
20ascorbic acid44 2410.0ALPP, IL1RN, TNFRSF11B
21sb 20358044 6110.0IL1RN, TNFRSF11B, ALPP
22etanercept44 50 1110.9IL11, IL1RN, TNFRSF11B
23infliximab44 50 1110.9IL11, TNFRSF11B, IL1RN
24pge1448.9ALPP, IL11, IL1RN
25polyethylene glycol448.9IL11, IL1RN, ALPP
26tgf beta1448.9IL1RN, TNFRSF11B, IL11
27rantes448.8IL1RN, IL11, TNFRSF11B
28norepinephrine44 24 1110.8SQSTM1, ALPP, IL1RN
29indomethacin44 28 61 1111.7TNFRSF11B, IL1RN, IL11
30hydroxyapatite448.7TNFRSF11A, ALPP, IL11, TNFRSF11B
311,25 dihydroxy vitamin d3448.6ALPP, TNFRSF11A, IL11, TNFRSF11B
32calcitriol44 61 24 1111.6ALPP, IL11, TNFRSF11A, TNFRSF11B
33prostaglandin448.5TNFRSF11B, TNFRSF11A, IL11, IL1RN
34fibrinogen448.5IL1RN, IL11, TNFRSF11B
35phosphatidylinositol448.4IL11, TNFRSF11B, TNFRSF11A, IL1RN
36nitric oxide44 24 1110.4IL1RN, IL11, TNFRSF11B, TNFRSF11A
37oxygen44 249.4SQSTM1, IL1RN, TNFRSF11A, IL11
38vitamin d448.4ALPP, IL1RN, IL11, TNFRSF11B
39cyclosporin a44 28 6110.4ALPP, IL1RN, TNFRSF11B, IL11
40heparin44 28 24 1111.4TNFRSF11B, IL11, IL1RN, ALPP
41cycloheximide448.4ALPP, IL1RN, IL11, TNFRSF11B
42retinoic acid44 249.2IL11, TNFRSF11B, ALPP, IL1RN
43cysteine448.2ALPP, IL1RN, IL11, TNFRSF11B
44pge2448.0ALPP, IL1RN, TNFRSF11A, TNFRSF11B, IL11
45dexamethasone44 50 28 1111.0ALPP, IL1RN, IL11, TNFRSF11B, TNFRSF11A
46vegf448.0IL11, ALPP, TNFRSF11B, TNFRSF11A, IL1RN
47tyrosine448.0IL11, SQSTM1, TNFRSF11A, IL1RN, TNFRSF11B
48estrogen448.0TNFRSF11B, IL11, ALPP, IL1RN, TNFRSF11A
49calcium44 50 24 1110.9ALPP, TNFRSF11A, IL1RN, IL11, TNFRSF11B
50serine447.6TNFRSF11B, TNFRSF11A, SQSTM1, ALPP, IL1RN, IL11

GO Terms for genes affiliated with Periostitis

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Biological processes related to Periostitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to lipopolysaccharideGO:0324969.4IL1RN, TNFRSF11A
2positive regulation of JUN kinase activityGO:0435079.1IL1RN, TNFRSF11A

Products for genes affiliated with Periostitis

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Sources for Periostitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet