Summaries for Periostitis

About this section


Wikipedia:63 Periostitis, also known as periostalgia, is a medical condition caused by inflammation of the... more...

MalaCards based summary: Periostitis is related to osteitis fibrosa and gingivitis. An important gene associated with Periostitis is TNFRSF11A (tumor necrosis factor receptor superfamily, member 11a, NFKB activator), and among its related pathways are Apoptosis and survival Anti apoptotic TNFs NF kB Bcl 2 pathway and TRAF Pathway. The compounds denosumab and polyethylene have been mentioned in the context of this disorder. Affiliated tissues include bone, lung and endothelial, and related mouse phenotypes are hematopoietic system and skeleton.

Aliases & Classifications for Periostitis

About this section

Related Diseases for Periostitis

About this section

Diseases related to Periostitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 166)
idRelated DiseaseScoreTop Affiliating Genes
1osteitis fibrosa30.6ALPP
2gingivitis30.4TNFRSF11B, ALPP
3periodontitis30.0IL1RN, TNFRSF11B
4renal osteodystrophy30.0TNFRSF11B, ALPP
5inflammatory bowel disease29.9IL1RN, ALPP
6colitis29.9IL1RN, IL11
7arthritis29.8TNFRSF11A, TNFRSF11B, IL1RN, ALPP
8thrombocytopenia29.6IL11, ALPP
9osteoarthritis29.6TNFRSF11B, IL1RN, TNFRSF11A
10hypercalcemia29.6TNFRSF11B, ALPP, TNFRSF11A
11rheumatoid arthritis29.5TNFRSF11B, IL11, IL1RN, TNFRSF11A
12secondary syphilis29.5ALPP, IL11, TNFRSF11B, TNFRSF11A
13periodontal disease28.9TNFRSF11A, TNFRSF11B, IL11, IL1RN, ALPP
14osteosarcoma, somatic28.9TNFRSF11B, IL1RN, IL11, TNFRSF11A, ALPP
15breast cancer28.9SQSTM1, TNFRSF11A, TNFRSF11B, IL11, ALPP
16chondroma10.8
17chondrosarcoma10.6
18periosteal chondrosarcoma10.6
19osteomyelitis10.5
20osteoblastoma10.5
21periosteal osteogenic sarcoma10.4
22syphilis10.4
23alveolar periostitis10.3
24sarcoma10.3
25paget disease of bone10.2TNFRSF11A, SQSTM1
26juxtacortical chondroma10.2
27polyarteritis nodosa10.2
28orbital periostitis10.2
29hyperostosis10.2
30keratitis10.2
31interleukin 1 receptor antagonist deficiency10.2
32osteonecrosis10.2
33typhoid fever10.2
34congenital syphilis10.2
35myositis10.2
36neutropenia10.1IL11, IL1RN
37leukopenia10.1ALPP, IL11
38crohn's disease10.1
39gingival recession10.1
40osteochondritis dissecans10.1
41cervicitis10.1
42fasciitis10.1
43interstitial keratitis10.1
44vasculitis10.1
45enchondroma10.1
46endotheliitis10.1
47paget disease, juvenile10.1TNFRSF11A, TNFRSF11B
48giant cell tumor10.1TNFRSF11B, TNFRSF11A
49osteopetrosis10.1TNFRSF11B, TNFRSF11A
50pancreatitis10.1ALPP, IL11

Graphical network of the top 20 diseases related to Periostitis:



Diseases related to periostitis

Symptoms for Periostitis

About this section

Drugs & Therapeutics for Periostitis

About this section

Drug clinical trials:

Search ClinicalTrials for Periostitis

Search NIH Clinical Center for Periostitis

Genetic Tests for Periostitis

About this section

Anatomical Context for Periostitis

About this section

MalaCards organs/tissues related to Periostitis:

31
Bone, Lung, Endothelial, Heart, Testes, Bone marrow, Brain, Liver, Breast

Animal Models for Periostitis or affiliated genes

About this section

MGI Mouse Phenotypes related to Periostitis:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053978.5SQSTM1, IL1RN, TNFRSF11B, TNFRSF11A
2MP:00053908.4TNFRSF11A, TNFRSF11B, IL1RN, SQSTM1
3MP:00053787.9SQSTM1, ALPP, IL1RN, TNFRSF11B, TNFRSF11A
4MP:00107687.6TNFRSF11A, TNFRSF11B, IL1RN, ALPP, SQSTM1

Publications for Periostitis

About this section

Articles related to Periostitis:

(show top 50)    (show all 429)
idTitleAuthorsYear
1
Periostitis ossificans managed with endodontic treatment. (25909844)
2015
2
Periosteal chondrosarcoma: a histopathological and molecular analysis of a rare chondrosarcoma subtype. (25648524)
2015
3
Usefulness of PET/CT for diagnosis of periosteal chondrosarcoma of the femur: A case report. (24932240)
2014
4
Periosteal microcirculatory reactions in a zoledronate-induced osteonecrosis model of the jaw in rats. (25352470)
2014
5
Plasma fluoride level as a predictor of voriconazole-induced periostitis in patients with skeletal pain. (24992954)
2014
6
High-concentration of BMP2 reduces cell proliferation and increases apoptosis via DKK1 and SOST in human primary periosteal cells. (23360788)
2013
7
Oral medicine case book 45. Periosteal osteosarcoma of the mandible. (23957106)
2012
8
Florid-reactive periostitis of the phalanges: a 2-case report. (22327452)
2012
9
Periosteal Flap fixation of the Globe for Surgical Treatment of Severe Restrictive Strabismus: A Report of Eight Cases with Outcomes. (22204549)
2011
10
Platelet-derived growth factor-BB release profile in gingival crevicular fluid after use of marginal periosteal pedicle graft as an autogenous guided tissue membrane to treat localized intrabony defects. (20681813)
2011
11
Periosteal chondroma of the pediatric cervical spine. (19278317)
2009
12
Syphilitic periostitis. (19393487)
2009
13
Survivorship analysis in patients with periosteal chondrosarcoma. (16826117)
2006
14
A rare case of periosteal osteoblastoma located in the frontal cranial bone. (15913430)
2005
15
In vitro osteogenic differentiation and in vivo bone-forming capacity of human isogenic jaw periosteal cells and bone marrow stromal cells. (16327496)
2005
16
FGF-2 enhances TGF-beta1-induced periosteal chondrogenesis. (15304287)
2004
17
Periosteal hyperostosis (exostosis) in DBA/1 male mice. (12051556)
2002
18
Prevention of postoperative meatal stenosis with anteriorly and inferiorly based periosteal flaps in congenital aural atresia surgery. (11773841)
2002
19
Periosteal chondroma presenting as a subcutaneous mass in the thumb. (11733159)
2001
20
Isolation of a cDNA sequence of rabbit GDF5 (mature form) and pattern of its mRNA expression during periosteal chondrogenesis. (11252805)
2000
21
Florid reactive periostitis ossificans of the proximal aspect of the tibia: a lesion that must be distinguished from osteosarcoma. A case report. (10428133)
1999
22
Gross periostitis ossificans in mandibular osteomyelitis. Review of the English literature and radiographic variation. (9768431)
1998
23
Musculoskeletal case of the day. Periosteal (juxtacortical) chondroma. (7785598)
1995
24
Mechanical loading stimulates rapid changes in periosteal gene expression. (7895187)
1994
25
Scintigraphic diagnosis of costal periostitis in actinomycosis. (1638850)
1992
26
Iliac periosteal graft with vascular pedicle in the treatment of avascular necrosis of the femoral head. Experimental study and clinical application. (1291204)
1992
27
Effect of lipopolysaccharide from Porphyromonas gingivalis on prostaglandin E2 and interleukin-1-beta release from rat periosteal and human gingival fibroblasts in vitro. (1668251)
1991
28
Cranial fasciitis of childhood with reactive periostitis. (2305359)
1990
29
Massive florid reactive periostitis. (2191267)
1990
30
Bizarre parosteal osteochondromatous proliferation vs. benign florid reactive periostitis. (3492900)
1987
31
Periosteal chondroma: a review of the literature and case report. (3512684)
1986
32
Florid reactive periostitis of the proximal phalanx. Case report. (4019546)
1985
33
Periostitis and osteitis associated with hyaline bodies. (2413879)
1985
34
Pain and periostitis. (4045899)
1985
35
Periosteal chondroma: another cause of carpal tunnel syndrome. (6721390)
1984
36
Periosteal chondroma. A review of twenty cases. (6822582)
1983
37
Ossifying granulomatous periostitis in the course of erythema nodosum. (753821)
1978
38
Periosteal chondroma. (4506239)
1972
39
Periostitis: an early diagnostic sign of juvenile rheumatoid arthritis. (6022368)
1967
40
Electron microscopic study of periosteal hyperostosis in rats with lathyrism induced by aminoacetonitrile. (5234345)
1966
41
PERIOSTITIS OSSIFICANS; ETIOLOGY OF FORMATION AND REPORT OF A CASE. (14176596)
1964
42
Chronic polyostotic periostitis of unknown etiology. (14036714)
1961
43
Pulmonary hypertrophic osteoarthropathy (periostitis); its absence in pulmonary tuberculosis. (13552924)
1958
44
Periostitis of the os calcis; an osteoperiosteal manifestation of rheumatoid arthritis. (18856913)
1948
45
Periostitis. ? Cause. (19988280)
1931
46
Osteo-periostitis of Upper End of Femur. (19978339)
1914
47
Acute Periostitis of Rib with Separation of Sequestra (Non-tuberculous, Non-traumatic). (19975692)
1912
48
Acute Infectious Osteomyelitis and Periostitis. (17857400)
1889
49
Periostitis in Typhoid Fever. (20751254)
1885
50
Vitamin-C Deficiency and Periostitis of Both UlnA (20916142)
.? Scurvy.

Variations for Periostitis

About this section

Expression for genes affiliated with Periostitis

About this section
Search GEO for disease gene expression data for Periostitis.

Pathways for genes affiliated with Periostitis

About this section

Pathways related to Periostitis according to GeneCards Suite gene sharing:

(show all 12)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Apoptosis and survival Anti apoptotic TNFs NF kB IAP pathway58
9.6SQSTM1, TNFRSF11A
2
Show member pathways
9.5TNFRSF11B, TNFRSF11A
3
Show member pathways
9.5TNFRSF11B, TNFRSF11A
49.5TNFRSF11A, TNFRSF11B
59.5TNFRSF11A, TNFRSF11B
6
Show member pathways
Prolactin Signaling Pathway36
Development Prolactin receptor signaling58
Leptin signaling pathway36
9.4IL1RN, TNFRSF11A
7
Show member pathways
9.4IL1RN, SQSTM1
8
Show member pathways
IL-1 Signaling Pathway36
IL1-mediated signaling events36
9.4SQSTM1, IL1RN
99.2IL11, TNFRSF11A
10
Show member pathways
RANKL/RANK Signaling Pathway36
Apoptosis and survival APRIL and BAFF signaling58
9.1SQSTM1, TNFRSF11B, TNFRSF11A
119.1SQSTM1, TNFRSF11B, TNFRSF11A
12
Show member pathways
8.7IL11, TNFRSF11B, TNFRSF11A

Compounds for genes affiliated with Periostitis

About this section

Compounds related to Periostitis according to GeneCards Suite gene sharing:

(show top 50)    (show all 76)
idCompoundScoreTop Affiliating Genes
1denosumab43 1210.9TNFRSF11A, TNFRSF11B
2polyethylene439.9TNFRSF11A, TNFRSF11B
3etidronate439.8TNFRSF11B, ALPP
4vitamin k2439.8TNFRSF11B, ALPP
5pamidronate43 49 1211.7ALPP, TNFRSF11B
6risedronate43 49 28 59 1213.7ALPP, TNFRSF11B
7anakinra43 1210.7IL1RN, TNFRSF11B
8pmma439.5ALPP, TNFRSF11B
9pyridinoline439.5TNFRSF11B, ALPP
10zoledronic acid439.4ALPP, TNFRSF11B
11filgrastim43 1210.3IL1RN, IL11
12prednisolone43 28 1211.2ALPP, TNFRSF11B, IL1RN
13atorvastatin43 49 28 24 1213.2ALPP, IL1RN, TNFRSF11B
14hydrocortisone43 2 59 1212.2IL1RN, TNFRSF11B, ALPP
15gp 130439.1TNFRSF11A, IL11, TNFRSF11B
16titanium439.0TNFRSF11B, IL11, ALPP
17deoxypyridinoline439.0IL11, TNFRSF11B, ALPP
18alendronate43 49 1211.0ALPP, IL11, TNFRSF11B
19polymyxin b439.0IL1RN, TNFRSF11B
20ascorbic acid43 2410.0ALPP, IL1RN, TNFRSF11B
21sb 20358043 5910.0IL1RN, TNFRSF11B, ALPP
22etanercept43 49 1210.9IL11, IL1RN, TNFRSF11B
23infliximab43 49 1210.9IL11, TNFRSF11B, IL1RN
24pge1438.9ALPP, IL11, IL1RN
25polyethylene glycol438.9IL11, IL1RN, ALPP
26tgf beta1438.9IL1RN, TNFRSF11B, IL11
27rantes438.8IL1RN, IL11, TNFRSF11B
28norepinephrine43 24 1210.8SQSTM1, ALPP, IL1RN
29indomethacin43 28 59 1211.7TNFRSF11B, IL1RN, IL11
30hydroxyapatite438.7TNFRSF11A, ALPP, IL11, TNFRSF11B
311,25 dihydroxy vitamin d3438.6ALPP, TNFRSF11A, IL11, TNFRSF11B
32calcitriol43 59 24 1211.6ALPP, IL11, TNFRSF11A, TNFRSF11B
33prostaglandin438.5TNFRSF11B, TNFRSF11A, IL11, IL1RN
34fibrinogen438.5IL1RN, IL11, TNFRSF11B
35phosphatidylinositol438.4IL11, TNFRSF11B, TNFRSF11A, IL1RN
36nitric oxide43 24 1210.4IL1RN, IL11, TNFRSF11B, TNFRSF11A
37oxygen43 249.4SQSTM1, IL1RN, TNFRSF11A, IL11
38vitamin d438.4ALPP, IL1RN, IL11, TNFRSF11B
39cyclosporin a43 28 5910.4ALPP, IL1RN, TNFRSF11B, IL11
40heparin43 28 24 1211.4TNFRSF11B, IL11, IL1RN, ALPP
41cycloheximide438.4ALPP, IL1RN, IL11, TNFRSF11B
42retinoic acid43 249.2IL11, TNFRSF11B, ALPP, IL1RN
43cysteine438.2ALPP, IL1RN, IL11, TNFRSF11B
44pge2438.0ALPP, IL1RN, TNFRSF11A, TNFRSF11B, IL11
45dexamethasone43 49 28 1211.0ALPP, IL1RN, IL11, TNFRSF11B, TNFRSF11A
46vegf438.0IL11, ALPP, TNFRSF11B, TNFRSF11A, IL1RN
47tyrosine438.0IL11, SQSTM1, TNFRSF11A, IL1RN, TNFRSF11B
48estrogen438.0TNFRSF11B, IL11, ALPP, IL1RN, TNFRSF11A
49calcium43 49 24 1210.9ALPP, TNFRSF11A, IL1RN, IL11, TNFRSF11B
50serine437.6TNFRSF11B, TNFRSF11A, SQSTM1, ALPP, IL1RN, IL11

GO Terms for genes affiliated with Periostitis

About this section

Biological processes related to Periostitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1response to lipopolysaccharideGO:00324969.4IL1RN, TNFRSF11A
2positive regulation of JUN kinase activityGO:00435079.1IL1RN, TNFRSF11A

Products for genes affiliated with Periostitis

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Periostitis

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet