Aliases & Classifications for Peripheral Vertigo

MalaCards integrated aliases for Peripheral Vertigo:

Name: Peripheral Vertigo 12 14
Vertigo, Peripheral 69

Classifications:



External Ids:

Disease Ontology 12 DOID:9847
ICD9CM 34 386.1 386.19

Summaries for Peripheral Vertigo

MalaCards based summary : Peripheral Vertigo, also known as vertigo, peripheral, is related to malignant otitis externa and paracetamol poisoning, and has symptoms including vertigo An important gene associated with Peripheral Vertigo is COCH (Cochlin), and among its related pathways/superpathways are Collagen chain trimerization and Formation of Fibrin Clot (Clotting Cascade). The drugs Piracetam and Histamine have been mentioned in the context of this disorder. Affiliated tissues include neutrophil, and related phenotypes are homeostasis/metabolism and nervous system

Related Diseases for Peripheral Vertigo

Diseases related to Peripheral Vertigo via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 153)
# Related Disease Score Top Affiliating Genes
1 malignant otitis externa 10.6 CRP F2
2 paracetamol poisoning 10.6 F2 F5
3 cerebral falx meningioma 10.6 F2 F3
4 acquired angioedema 10.5 CRP F5
5 von willebrand disease, type 1 10.5 F2 F3
6 acquired hemophilia a 10.5 F3 F5
7 ischemic neuropathy 10.5 CRP F2
8 central nervous system origin vertigo 10.5
9 qualitative platelet defect 10.5 F2 F3
10 acquired hemophilia 10.5 F3 F5
11 may-thurner syndrome 10.5 APOH F5
12 blood protein disease 10.5 F2 SERPINC1
13 intracranial sinus thrombosis 10.5 F3 SERPINC1
14 heparin-induced thrombocytopenia 10.5 F3 SERPINC1
15 alpha-2-plasmin inhibitor deficiency 10.5 F2 SERPINC1
16 hemoglobin e disease 10.5 F2 F5
17 acanthamoeba keratitis 10.5 APOH F5
18 mediastinitis 10.5 CRP F5
19 splenic infarction 10.5 APOH F2
20 sticky platelet syndrome 10.5 F5 SERPINC1
21 femoral neuropathy 10.5 F2 F3
22 japanese spotted fever 10.5 CRP SERPINC1
23 alcohol-related birth defect 10.5 F2 F3
24 hantavirus pulmonary syndrome 10.5 F2 F3
25 cryptogenic cirrhosis 10.5 F2 F5
26 anterior cranial fossa meningioma 10.5 F2 F3
27 pregnancy loss, recurrent 1 10.5 APOH F5
28 papilledema 10.5 APOH F2
29 factor viii deficiency 10.5 F2 F5
30 anterior spinal artery syndrome 10.5 F2 SERPINC1
31 splenic disease 10.4 F2 F3
32 subendocardial myocardial infarction 10.4 F2 SERPINC1
33 porencephaly 10.4 F2 F5
34 endocardium disease 10.4 CRP F2 F3
35 arteritic anterior ischemic optic neuropathy 10.4 CRP F2 F5
36 intestinal impaction 10.4 F2 F3 SERPINC1
37 fournier gangrene 10.4 F2 F3 SERPINC1
38 angina pectoris 10.4 CRP F3 SERPINC1
39 factor v deficiency 10.4 F2 F3 F5
40 leech infestation 10.4 F2 F3 SERPINC1
41 giant hemangioma 10.4 F2 F3 SERPINC1
42 intracranial embolism 10.4 F2 F3 SERPINC1
43 intermediate coronary syndrome 10.4 CRP F3 SERPINC1
44 marantic endocarditis 10.4 F2 F3 SERPINC1
45 severe hemophilia a 10.4 F2 F3 F5
46 purpura fulminans 10.4 F2 F3 SERPINC1
47 esophageal varix 10.4 F2 SERPINC1
48 sudden sensorineural hearing loss 10.4 F2 F5 SERPINC1
49 thrombasthenia 10.4 F2 F3 F5
50 korean hemorrhagic fever 10.4 F2 F3 SERPINC1

Comorbidity relations with Peripheral Vertigo via Phenotypic Disease Network (PDN):


Hypertension, Essential Ischemic Heart Disease
Labyrinthitis

Graphical network of the top 20 diseases related to Peripheral Vertigo:



Diseases related to Peripheral Vertigo

Symptoms & Phenotypes for Peripheral Vertigo

UMLS symptoms related to Peripheral Vertigo:


vertigo

MGI Mouse Phenotypes related to Peripheral Vertigo:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.7 APOH AQP2 AVP CRP F2 F3
2 nervous system MP:0003631 9.28 AVP CRLF1 F2 F3 F5 KCNE3

Drugs & Therapeutics for Peripheral Vertigo

Drugs for Peripheral Vertigo (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 29)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Piracetam Approved, Investigational Phase 4 7491-74-9
2
Histamine Approved, Investigational Phase 4,Phase 3 51-45-6, 75614-87-8 774
3
Dimenhydrinate Approved Phase 4 523-87-5 441281
4
Histamine Phosphate Phase 4,Phase 3 51-74-1 65513
5 Gastrointestinal Agents Phase 4,Phase 3
6 Neurotransmitter Agents Phase 4,Phase 3
7 Histamine Antagonists Phase 4,Phase 3
8 Histamine H1 Antagonists Phase 4,Phase 3
9 Peripheral Nervous System Agents Phase 4,Phase 3
10 Antiemetics Phase 4,Phase 3
11 Autonomic Agents Phase 4,Phase 3
12
Diphenhydramine Approved, Investigational Phase 3 58-73-1, 147-24-0 3100
13
Lorazepam Approved Phase 3 846-49-1 3958
14
Promethazine Approved, Investigational Phase 3 60-87-7 4927
15 Central Nervous System Depressants Phase 3
16 GABA Agents Phase 3
17 GABA Modulators Phase 3
18 Tranquilizing Agents Phase 3
19 Anesthetics Phase 3
20 Dermatologic Agents Phase 3
21 Anesthetics, Local Phase 3
22 Anti-Allergic Agents Phase 3
23 Anti-Anxiety Agents Phase 3
24 Hypnotics and Sedatives Phase 3
25 Anticonvulsants Phase 3
26 Psychotropic Drugs Phase 3
27 Antipruritics Phase 3
28
Betahistine Approved, Investigational 5638-76-6 2366
29 Vasodilator Agents

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Comparison of Efficacy Between Piracetam and Dimenhydrinate in Patients With Peripheral Vertigo Completed NCT01890538 Phase 4 Administration of 100 mg dimenhydrinate intravenous;2 g piracetam intravenous
2 Promethazine vs. Lorazepam for Treatment of Vertigo Completed NCT01827293 Phase 3 Promethazine;Lorazepam
3 Effectiveness of Betaserc® (Betahistine Dihydrochloride) in Patients With Vestibular Vertigo in Routine Practice Completed NCT01759251
4 Diagnosis Of Vertigo With New Imaging Completed NCT00593216
5 Effects of a Vestibular Rehabilitation Maneuver Completed NCT01080430

Search NIH Clinical Center for Peripheral Vertigo

Genetic Tests for Peripheral Vertigo

Anatomical Context for Peripheral Vertigo

MalaCards organs/tissues related to Peripheral Vertigo:

38
Neutrophil

Publications for Peripheral Vertigo

Articles related to Peripheral Vertigo:

(show all 47)
# Title Authors Year
1
Author response: Clinical Reasoning: Labyrinthine hemorrhage: An unusual etiology for peripheral vertigo. ( 29335312 )
2018
2
New Onset Focal Stabbing Headache Associated With Peripheral Vertigo: A Case Report. ( 29034450 )
2018
3
Reader response: Clinical Reasoning: Labyrinthine hemorrhage: An unusual etiology for peripheral vertigo. ( 29335311 )
2018
4
Decompensated labyrinthine weakness presenting as de novo peripheral vertigo: a discrete clinical entity? ( 29343311 )
2018
5
Editors' note: Clinical Reasoning: Labyrinthine hemorrhage: An unusual etiology for peripheral vertigo. ( 29335310 )
2018
6
The impact of opioid medications on subsequent fractures in discharged emergency department patients with peripheral vertigo. ( 28631577 )
2017
7
A Comparison of the Effects and Side Effects of Oral Betahistine with Injectable Promethazine in the Treatment of Acute Peripheral Vertigo in Emergency. ( 29163732 )
2017
8
Clinical Reasoning: Labyrinthine hemorrhage: An unusual etiology for peripheral vertigo. ( 28069982 )
2017
9
THE USEFULNESS OF MONITORING THE NEUTROPHIL TO LYMPHOCYTE RATIO IN PATIENTS WITH PERIPHERAL VERTIGO. ( 27661276 )
2016
10
Effect of a vestibular rehabilitation protocol to improve the health-related quality of life and postural balance in patients with peripheral vertigo. ( 27676762 )
2016
11
Outcomes among patients discharged from the emergency department with a diagnosis of peripheral vertigo. ( 26385410 )
2015
12
Anxiety and depression among patients with different types of vestibular peripheral vertigo. ( 25654382 )
2015
13
Use of betahistine in the treatment of peripheral vertigo. ( 26245698 )
2015
14
Histamine Antagonists for Treatment of Peripheral Vertigo: A Meta-Analysis. ( 26381004 )
2015
15
Associations between peripheral vertigo and gastroesophageal reflux disease. ( 26115947 )
2015
16
Intravenous promethazine versus lorazepam for the treatment of peripheral vertigo in the emergency department: A double blind, randomized clinical trial of efficacy and safety. ( 24594499 )
2014
17
Neutrophil-to-lymphocyte ratio in patients with peripheral vertigo: A prospective controlled clinical study. ( 25219290 )
2014
18
Cerebellar infarctions mimicking acute peripheral vertigo: how to avoid misdiagnosis? ( 23307911 )
2013
19
Response to: "Cerebellar infarctions mimicking acute peripheral vertigo," from Yeo et al. ( 23633501 )
2013
20
Evaluation of the effect of nimodipine o.d. (extended release) vs nimodipine t.i.d. in the treatment of peripheral vertigo. ( 23808594 )
2013
21
Letter to the editor on "Cerebellar infarctions mimicking acute peripheral vertigo: how to avoid misdiagnosis?". ( 23633500 )
2013
22
Comparison of the effectiveness of intravenous piracetam and intravenous dimenhydrinate in the treatment of acute peripheral vertigo in the emergency department. ( 24276103 )
2013
23
An easy diagnostic tool distinguishing lateral medullary infarction from peripheral vertigo. ( 21855212 )
2012
24
Medullary infarction after vertebral artery dissection presenting as acute peripheral vertigo. ( 21307810 )
2011
25
Sonographic examination of epiaortic vessels in patients with peripheral vertigo. ( 23396499 )
2010
26
Is surgical vestibular ablation necessary in disabling peripheral vertigo? ( 23120494 )
2008
27
Stiff-person syndrome with acute recurrent peripheral vertigo: possible evidence of gamma aminobutyric acid as a neurotransmitter in the vestibular periphery. ( 17666138 )
2008
28
Role of C-reactive protein, D-dimer, and fibrinogen levels in the differential diagnosis of central and peripheral vertigo. ( 18029334 )
2007
29
Intracranial vertebral artery dissection mimicking acute peripheral vertigo. ( 16428195 )
2006
30
Surgical treatment of peripheral vertigo and vertiginous diseases. ( 15637415 )
2005
31
Intratympanic gentamicin for the treatment of Meniere's disease and other forms of peripheral vertigo. ( 15474112 )
2004
32
Relevance of plasma D-dimer measurement in patients with acute peripheral vertigo. ( 12818056 )
2003
33
Acute peripheral vertigo: involvement of the hemostatic system. ( 15106288 )
2003
34
New approaches to the management of peripheral vertigo: efficacy and safety of two calcium antagonists in a 12-week, multinational, double-blind study. ( 11981396 )
2002
35
Intramuscular droperidol versus intramuscular dimenhydrinate for the treatment of acute peripheral vertigo in the emergency department: a randomized clinical trial. ( 12045085 )
2002
36
A study on peripheral vertigo in a Kolkata based hospital. ( 23119868 )
2002
37
Droperidol for the treatment of acute peripheral vertigo. ( 9928721 )
1999
38
Posterior fossa vestibular nerve section for the management of peripheral vertigo. ( 10392296 )
1999
39
3D analysis of nystagmus in peripheral vertigo. ( 9105433 )
1997
40
Surgical treatment of incapacitating peripheral vertigo. Criteria for the evaluation of surgical results. ( 8022609 )
1994
41
Overall view and rationale for surgical alternatives for incapacitating peripheral vertigo. ( 8022608 )
1994
42
Transdermal scopolamine for peripheral vertigo (a double-blind study). ( 3894551 )
1985
43
Peripheral vertigo. ( 3979333 )
1985
44
The causes of peripheral vertigo. ( 6499708 )
1984
45
Complications of treatment of peripheral vertigo. ( 6149924 )
1984
46
Peripheral vertigo. ( 6499706 )
1984
47
Betahistine in peripheral vertigo: a double-blind, placebo-controlled, cross-over study of Serc versus placebo. ( 7019369 )
1981

Variations for Peripheral Vertigo

Expression for Peripheral Vertigo

Search GEO for disease gene expression data for Peripheral Vertigo.

Pathways for Peripheral Vertigo

GO Terms for Peripheral Vertigo

Cellular components related to Peripheral Vertigo according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.76 APOH AQP2 COCH CRP F2 F3
2 extracellular space GO:0005615 9.5 APOH CRLF1 CRP F2 F3 F5
3 extracellular region GO:0005576 9.32 APOH AVP COCH CRLF1 CRP ENSG00000258417

Biological processes related to Peripheral Vertigo according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 blood coagulation GO:0007596 9.46 F2 F3 F5 SERPINC1
2 blood coagulation, intrinsic pathway GO:0007597 9.4 APOH F2
3 water transport GO:0006833 9.37 AQP2 AVP
4 positive regulation of blood coagulation GO:0030194 9.32 APOH F2
5 negative regulation of fibrinolysis GO:0051918 9.26 APOH F2
6 regulation of blood coagulation GO:0030193 9.13 APOH F2 SERPINC1
7 hemostasis GO:0007599 8.92 F2 F3 F5 SERPINC1

Molecular functions related to Peripheral Vertigo according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 heparin binding GO:0008201 8.8 APOH F2 SERPINC1

Sources for Peripheral Vertigo

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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