MCID: PRP028
MIFTS: 41

Peripheral Vertigo malady

Ear diseases category
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Summaries for Peripheral Vertigo

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MalaCards based summary: Peripheral Vertigo, also known as vertigo, peripheral, is related to thrombophlebitis and retinal artery occlusion. An important gene associated with Peripheral Vertigo is GAD1 (glutamate decarboxylase 1 (brain, 67kDa)), and among its related pathways are Selected targets of HNF1 and Selenium Pathway. The compounds celite and aprosulate have been mentioned in the context of this disorder. Affiliated tissues include neutrophil, and related mouse phenotypes are embryogenesis and cardiovascular system.

Aliases & Classifications for Peripheral Vertigo

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Peripheral Vertigo, Aliases & Descriptions:

Name: Peripheral Vertigo 8
 
Vertigo, Peripheral 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Ear diseases


External Ids:

Disease Ontology8 DOID:9847
ICD9CM27 386.1, 386.19

Related Diseases for Peripheral Vertigo

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Diseases related to Peripheral Vertigo via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 78)
idRelated DiseaseScoreTop Affiliating Genes
1thrombophlebitis10.5APOH
2retinal artery occlusion10.5APOH
3central retinal vein occlusion10.5APOH
4factor xii deficiency10.4F3
5carotid artery thrombosis10.4F3
6factor viii deficiency10.4F3
7purpura10.4SERPINC1
8sagittal sinus thrombosis10.4SERPINC1
9blindness10.4
10eclampsia10.3SERPINC1
11hypersplenism10.2F2
12systemic lupus erythematosus10.2CRP
13sneddon syndrome10.2SERPINC1, APOH
14hepatic vein thrombosis10.2SERPINC1, APOH
15retinal vein occlusion10.2SERPINC1, APOH
16thrombotic thrombocytopenic purpura, acquired10.2F3, APOH
17severe pre-eclampsia10.2APOH, SERPINC1
18hellp syndrome10.1APOH, SERPINC1
19behcet's disease10.1APOH, CRP
20blood platelet disease10.1F3, SERPINC1
21coronary thrombosis10.1F3, SERPINC1
22hemolytic anemia10.1F3, APOH
23glucose intolerance10.1CRP, GAD1
24rheumatic disease10.1APOH, CRP
25stiff-person syndrome10.1
26meniere's disease10.1
27factor x deficiency10.1F2, F3
28factor v deficiency10.1F3, F2
29vitamin k deficiency hemorrhagic disease10.1F2, F3
30factor xi deficiency10.1F3, F2
31von willebrand's disease10.0F3, F2
32afibrinogenemia10.0F2, F3
33blood protein disease10.0F2, SERPINC1
34portal vein thrombosis10.0SERPINC1, F2
35hemophilia b10.0F3, F2
36dysfibrinogenemia10.0SERPINC1, F2
37placental abruption10.0F2, SERPINC1
38intracranial thrombosis10.0SERPINC1, APOH, F3
39galactosemia10.0F3, F2
40prion disease10.0F3, SERPINC1
41sjogren's syndrome10.0APOH, GAD1
42peritonitis10.0F2, CRP
43respiratory failure9.9CRP, SERPINC1, F3
44septic shock9.9F3, SERPINC1, CRP
45acute myocardial infarction9.9SERPINC1, CRP, F3
46connective tissue disease9.9F2, APOH, F3
47diabetes mellitus9.9GAD1, CRP, SERPINC1
48vasculitis9.9APOH, F2, CRP
49myocardial infarction9.9SERPINC1, F3, CRP
50prothrombin deficiency9.9SERPINC1, APOH, F2

Graphical network of the top 20 diseases related to Peripheral Vertigo:



Diseases related to peripheral vertigo

Symptoms for Peripheral Vertigo

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Drugs & Therapeutics for Peripheral Vertigo

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Drug clinical trials:

Search ClinicalTrials for Peripheral Vertigo

Search NIH Clinical Center for Peripheral Vertigo

Genetic Tests for Peripheral Vertigo

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Anatomical Context for Peripheral Vertigo

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MalaCards organs/tissues related to Peripheral Vertigo:

32
Neutrophil

Animal Models for Peripheral Vertigo or affiliated genes

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MGI Mouse Phenotypes related to Peripheral Vertigo:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053808.0F2, SERPINC1, F3, GAD1
2MP:00053858.0CRP, F3, SERPINC1, F2
3MP:00107687.3F2, APOH, SERPINC1, F3, GAD1
4MP:00053767.1GAD1, CRP, F3, SERPINC1, APOH, F2

Publications for Peripheral Vertigo

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Articles related to Peripheral Vertigo:

(show all 31)
idTitleAuthorsYear
1
Neutrophil-to-lymphocyte ratio in patients with peripheral vertigo: A prospective controlled clinical study. (25219290)
2014
2
Intravenous promethazine versus lorazepam for the treatment of peripheral vertigo in the emergency department: A double blind, randomized clinical trial of efficacy and safety. (24594499)
2014
3
Evaluation of the effect of nimodipine o.d. (extended release) vs nimodipine t.i.d. in the treatment of peripheral vertigo. (23808594)
2013
4
Comparison of the effectiveness of intravenous piracetam and intravenous dimenhydrinate in the treatment of acute peripheral vertigo in the emergency department. (24276103)
2013
5
Cerebellar infarctions mimicking acute peripheral vertigo: how to avoid misdiagnosis? (23307911)
2013
6
Letter to the editor on "Cerebellar infarctions mimicking acute peripheral vertigo: how to avoid misdiagnosis?". (23633500)
2013
7
Response to: "Cerebellar infarctions mimicking acute peripheral vertigo," from Yeo et al. (23633501)
2013
8
An easy diagnostic tool distinguishing lateral medullary infarction from peripheral vertigo. (21855212)
2012
9
Medullary infarction after vertebral artery dissection presenting as acute peripheral vertigo. (21307810)
2011
10
Sonographic examination of epiaortic vessels in patients with peripheral vertigo. (23396499)
2010
11
Is surgical vestibular ablation necessary in disabling peripheral vertigo? (23120494)
2008
12
Stiff-person syndrome with acute recurrent peripheral vertigo: possible evidence of gamma aminobutyric acid as a neurotransmitter in the vestibular periphery. (17666138)
2008
13
Role of C-reactive protein, D-dimer, and fibrinogen levels in the differential diagnosis of central and peripheral vertigo. (18029334)
2007
14
Intracranial vertebral artery dissection mimicking acute peripheral vertigo. (16428195)
2006
15
Surgical treatment of peripheral vertigo and vertiginous diseases. (15637415)
2005
16
Intratympanic gentamicin for the treatment of Meniere's disease and other forms of peripheral vertigo. (15474112)
2004
17
Acute peripheral vertigo: involvement of the hemostatic system. (15106288)
2003
18
New approaches to the management of peripheral vertigo: efficacy and safety of two calcium antagonists in a 12-week, multinational, double-blind study. (11981396)
2002
19
A study on peripheral vertigo in a Kolkata based hospital. (23119868)
2002
20
Intramuscular droperidol versus intramuscular dimenhydrinate for the treatment of acute peripheral vertigo in the emergency department: a randomized clinical trial. (12045085)
2002
21
Posterior fossa vestibular nerve section for the management of peripheral vertigo. (10392296)
1999
22
Droperidol for the treatment of acute peripheral vertigo. (9928721)
1999
23
3D analysis of nystagmus in peripheral vertigo. (9105433)
1997
24
Overall view and rationale for surgical alternatives for incapacitating peripheral vertigo. (8022608)
1994
25
Surgical treatment of incapacitating peripheral vertigo. Criteria for the evaluation of surgical results. (8022609)
1994
26
Peripheral vertigo. (3979333)
1985
27
Transdermal scopolamine for peripheral vertigo (a double-blind study). (3894551)
1985
28
Complications of treatment of peripheral vertigo. (6149924)
1984
29
Peripheral vertigo. (6499706)
1984
30
The causes of peripheral vertigo. (6499708)
1984
31
Betahistine in peripheral vertigo: a double-blind, placebo-controlled, cross-over study of Serc versus placebo. (7019369)
1981

Variations for Peripheral Vertigo

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Expression for genes affiliated with Peripheral Vertigo

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Expression patterns in normal tissues for genes affiliated with Peripheral Vertigo

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Pathways for genes affiliated with Peripheral Vertigo

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Pathways related to Peripheral Vertigo according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5CRP, APOH
2
Show member pathways
thioredoxin pathway37
9.1CRP, F2
3
Show member pathways
8.5F3, SERPINC1, F2
4
Show member pathways
8.5F2, SERPINC1, F3
5
Show member pathways
Complement Activation, Classical Pathway37
Complement and Coagulation Cascades37
8.5F3, SERPINC1, F2
6
Show member pathways
8.5F3, SERPINC1, F2

Compounds for genes affiliated with Peripheral Vertigo

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Compounds related to Peripheral Vertigo according to GeneCards/GeneDecks:

(show top 50)    (show all 120)
idCompoundScoreTop Affiliating Genes
1celite449.5SERPINC1, F3
2aprosulate449.3F3, F2
3napsagatran449.2F2, F3
4brodifacoum449.2F2, F3
5ticlopidine44 1110.2APOH, SERPINC1, F3
6mnpt449.1F2, F3
7kaolin449.1APOH, F2, F3
8coumarins449.0F3, APOH, F2
9certoparin449.0F3, F2, SERPINC1
10inogatran448.9F2, F3, SERPINC1
11ecarin448.9F3, SERPINC1, F2
12spectrozyme448.9SERPINC1, F3, F2
13polybrene448.9F3, SERPINC1, F2
14hepaplastin448.9F2, SERPINC1, F3
15danaparoid448.9F3, F2, SERPINC1
16organon448.9F3, SERPINC1, F2
17ximelagatran44 119.9F2, SERPINC1, F3
18rivaroxaban44 119.9F3, SERPINC1, F2
19vitamin k144 249.9F3, SERPINC1, F2
20cardiolipin44 119.9F3, F2, APOH
21heparinoids448.9F3, F2, SERPINC1
22fondaparinux448.9SERPINC1, F3, F2
23bivalirudin44 119.9F3, SERPINC1, F2
24hydroxyethyl starch448.9SERPINC1, F3, F2
25dextran sulfate448.9F3, SERPINC1, APOH
26argatroban44 119.9F2, SERPINC1, F3
27phenprocoumon44 50 1110.9F2, SERPINC1, F3
28ppack448.9F2, F3, SERPINC1
29protamine sulfate448.9F2, F3, SERPINC1
30tranexamic acid44 119.8F2, F3, SERPINC1
31epsilon aminocaproic acid448.8F2, F3, SERPINC1
32ristocetin448.8F3, SERPINC1, F2
33levonorgestrel44 61 28 1111.8F2, F3, SERPINC1
34desmopressin44 61 28 1111.8F2, SERPINC1, F3
35coumarin44 2 50 2411.8F3, SERPINC1, F2
36hirudin448.7SERPINC1, F2, F3
37prostacyclin448.6CRP, SERPINC1, APOH, F3
38warfarin44 50 24 1111.5F2, APOH, SERPINC1, F3
39kininogen448.5SERPINC1, F3, APOH, F2
40tirofiban44 119.4SERPINC1, F2, F3, CRP
41abciximab44 119.4CRP, F3, F2, SERPINC1
42clopidogrel44 50 24 1111.4F2, SERPINC1, CRP, F3
43protamine448.4F3, F2, SERPINC1
44citrate448.3CRP, F2, SERPINC1, F3
45dermatan sulfate448.2SERPINC1, F2, F3
46homocysteine44 249.0F3, F2, SERPINC1, APOH, CRP
47aspirin44 50 28 2411.0F2, SERPINC1, F3, APOH, CRP
48fibrinogen447.9CRP, APOH, F3, SERPINC1, F2
49alanine447.8CRP, GAD1, F2, SERPINC1, F3
50creatinine447.6GAD1, F2, APOH, SERPINC1, F3, CRP

GO Terms for genes affiliated with Peripheral Vertigo

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Cellular components related to Peripheral Vertigo according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1blood microparticleGO:0725629.0SERPINC1, F2
2extracellular spaceGO:0056157.2CRP, F3, SERPINC1, APOH, F2

Biological processes related to Peripheral Vertigo according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of fibrinolysisGO:0519189.3APOH, F2
2positive regulation of blood coagulationGO:0301949.2APOH, F2
3blood coagulation, intrinsic pathwayGO:0075979.1F2, APOH
4acute-phase responseGO:0069538.8CRP, F2
5blood coagulationGO:0075968.5F3, SERPINC1, F2

Molecular functions related to Peripheral Vertigo according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1phospholipid bindingGO:0055439.5F3, APOH
2protease bindingGO:0020209.0F3, SERPINC1
3protein bindingGO:0055157.0GAD1, F2, APOH, SERPINC1, F3, CRP

Products for genes affiliated with Peripheral Vertigo

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Sources for Peripheral Vertigo

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet