MCID: PRP028
MIFTS: 36

Peripheral Vertigo malady

Summaries for Peripheral Vertigo

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32MalaCards
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MalaCards: Peripheral Vertigo, also known as vertigo, peripheral, is related to stiff-person syndrome and meniere's disease. An important gene associated with Peripheral Vertigo is GAD1 (glutamate decarboxylase 1 (brain, 67kDa)), and among its related pathways are Selected targets of HNF1 and Gamma-carboxylation, transport, and amino-terminal cleavage of proteins. The compounds dextran sulfate and warfarin have been mentioned in the context of this disorder. Related mouse phenotype homeostasis/metabolism.

Aliases & Classifications for Peripheral Vertigo

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Sources:
8Disease Ontology, 60UMLS, 56SNOMED-CT, 27ICD9CM
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Aliases & Descriptions:

peripheral vertigo 8
vertigo, peripheral 60


External Ids:

Disease Ontology8 DOID:9847
ICD9CM27 386.19, 386.1

Related Diseases for Peripheral Vertigo

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17GeneCards, 18GeneDecks
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Diseases related to Peripheral Vertigo via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 122)
idRelated DiseaseScoreTop Affiliating Genes
1stiff-person syndrome10.0
2meniere's disease10.0
3ischemia10.0GAD1
4thrombophlebitis10.0APOH
5diabetic retinopathy10.0GAD1
6retinal artery occlusion10.0APOH
7multiple sclerosis10.0GAD1
8central retinal vein occlusion10.0APOH
9cerebrovascular disease10.0APOH
10purpura fulminans10.0SERPINC1
11herpes simplex10.0GAD1
12acute pancreatitis10.0CRP
13purpura10.0SERPINC1
14nephrotic syndrome10.0SERPINC1
15aortic aneurysm10.0CRP
16eclampsia10.0SERPINC1
17retinal vascular occlusion10.0APOH
18familial mediterranean fever10.0CRP
19uremia10.0CRP
20hypercholesterolemia10.0CRP
21polycystic ovary syndrome10.0CRP
22pneumonia10.0CRP
23systemic lupus erythematosus10.0CRP
24sagittal sinus thrombosis10.0SERPINC1
25pulmonary disease, chronic obstructive10.0CRP
26breast cancer10.0GAD1
27obesity10.0CRP
28pancreatitis10.0CRP
29viral hepatitis10.0F2
30ulcerative colitis10.0CRP
31hepatitis a10.0F2
32hepatitis c10.0F2
33arthritis10.0CRP
34primary hyperoxaluria10.0SERPINC1
35graves' disease10.0GAD1
36diabetic ketoacidosis10.0GAD1
37kawasaki disease10.0CRP
38syphilis10.0APOH
39crohn's disease10.0CRP
40migraine10.0APOH
41hepatitis10.0F2
42hepatitis b10.0F2
43fatty liver disease10.0CRP
44nephritis10.0APOH
45collagen disease10.0CRP
46cholestasis10.0F2
47mixed connective tissue disease10.0APOH
48polymyalgia rheumatica10.0CRP
49factor xii deficiency10.0F3
50hemarthrosis10.0F3

Graphical network of the top 20 diseases related to Peripheral Vertigo:



Diseases related to peripheral vertigo

Clinical Features for Peripheral Vertigo

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Drugs & Therapeutics for Peripheral Vertigo

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Peripheral Vertigo

Drug clinical trials:

Search ClinicalTrials for Peripheral Vertigo

Search NIH Clinical Center for Peripheral Vertigo

Search CenterWatch for Peripheral Vertigo

Genetic Tests for Peripheral Vertigo

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Anatomical Context for Peripheral Vertigo

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Animal Models for Peripheral Vertigo or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Peripheral Vertigo:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053767.1SERPINC1, F2, F3, CRP, GAD1, APOH

Publications for Peripheral Vertigo

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50PubMed
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Articles related to Peripheral Vertigo:

(show all 30)
idTitleAuthorsYear
1
Evaluation of the effect of nimodipine o.d. (extended release) vs nimodipine t.i.d. in the treatment of peripheral vertigo. (23808594)
2013
2
Comparison of the effectiveness of intravenous piracetam and intravenous dimenhydrinate in the treatment of acute peripheral vertigo in the emergency department. (24276103)
2013
3
Cerebellar infarctions mimicking acute peripheral vertigo: how to avoid misdiagnosis? (23307911)
2013
4
Letter to the editor on "Cerebellar infarctions mimicking acute peripheral vertigo: how to avoid misdiagnosis?". (23633500)
2013
5
Response to: "Cerebellar infarctions mimicking acute peripheral vertigo," from Yeo et al. (23633501)
2013
6
An easy diagnostic tool distinguishing lateral medullary infarction from peripheral vertigo. (21855212)
2012
7
Medullary infarction after vertebral artery dissection presenting as acute peripheral vertigo. (21307810)
2011
8
Sonographic examination of epiaortic vessels in patients with peripheral vertigo. (23396499)
2010
9
Is surgical vestibular ablation necessary in disabling peripheral vertigo? (23120494)
2008
10
Stiff-person syndrome with acute recurrent peripheral vertigo: possible evidence of gamma aminobutyric acid as a neurotransmitter in the vestibular periphery. (17666138)
2008
11
Role of C-reactive protein, D-dimer, and fibrinogen levels in the differential diagnosis of central and peripheral vertigo. (18029334)
2007
12
Intracranial vertebral artery dissection mimicking acute peripheral vertigo. (16428195)
2006
13
Surgical treatment of peripheral vertigo and vertiginous diseases. (15637415)
2005
14
Intratympanic gentamicin for the treatment of Meniere's disease and other forms of peripheral vertigo. (15474112)
2004
15
Acute peripheral vertigo: involvement of the hemostatic system. (15106288)
2003
16
Relevance of plasma D-dimer measurement in patients with acute peripheral vertigo. (12818056)
2003
17
New approaches to the management of peripheral vertigo: efficacy and safety of two calcium antagonists in a 12-week, multinational, double-blind study. (11981396)
2002
18
A study on peripheral vertigo in a Kolkata based hospital. (23119868)
2002
19
Intramuscular droperidol versus intramuscular dimenhydrinate for the treatment of acute peripheral vertigo in the emergency department: a randomized clinical trial. (12045085)
2002
20
Posterior fossa vestibular nerve section for the management of peripheral vertigo. (10392296)
1999
21
Droperidol for the treatment of acute peripheral vertigo. (9928721)
1999
22
3D analysis of nystagmus in peripheral vertigo. (9105433)
1997
23
Overall view and rationale for surgical alternatives for incapacitating peripheral vertigo. (8022608)
1994
24
Surgical treatment of incapacitating peripheral vertigo. Criteria for the evaluation of surgical results. (8022609)
1994
25
Peripheral vertigo. (3979333)
1985
26
Transdermal scopolamine for peripheral vertigo (a double-blind study). (3894551)
1985
27
Complications of treatment of peripheral vertigo. (6149924)
1984
28
Peripheral vertigo. (6499706)
1984
29
The causes of peripheral vertigo. (6499708)
1984
30
Betahistine in peripheral vertigo: a double-blind, placebo-controlled, cross-over study of Serc versus placebo. (7019369)
1981

Genetic Variations for Peripheral Vertigo

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Expression for genes affiliated with Peripheral Vertigo

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Peripheral Vertigo

Search GEO for disease gene expression data for Peripheral Vertigo.

Pathways for genes affiliated with Peripheral Vertigo

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Sources:
12EMD Millipore, 53Reactome, 49PharmGKB, 51QIAGEN, 52R&D Systems, 37NCBI BioSystems Database, 29KEGG
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Compounds for genes affiliated with Peripheral Vertigo

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Sources:
44Novoseek, 49PharmGKB, 11DrugBank, 24HMDB, 59Tocris Bioscience, 28IUPHAR, 2BitterDB
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Compounds related to Peripheral Vertigo according to GeneCards/GeneDecks:

(show top 50)    (show all 107)
idCompoundScoreTop Affiliating Genes
1dextran sulfate449.9APOH
2warfarin44 49 11 2412.9APOH, SERPINC1
3aprosulate449.9F3
4brodifacoum449.8F3
5coumarins449.6APOH, F3
6celite449.3F3, SERPINC1
7napsagatran449.2F3, F2
8hemochron449.0F2, F3
9kaolin449.0F2, F3, APOH
10ticlopidine44 1110.0APOH, F3, SERPINC1
11certoparin449.0F3, F2, SERPINC1
12inogatran448.9F3, F2, SERPINC1
13ecarin448.9SERPINC1, F2, F3
14polybrene448.9F3, F2, SERPINC1
15spectrozyme448.9F3, F2, SERPINC1
16danaparoid448.9F3, F2, SERPINC1
17hepaplastin448.9F3, F2, SERPINC1
18organon448.9F2, F3, SERPINC1
19rivaroxaban44 119.9F3, F2, SERPINC1
20ximelagatran44 119.9F3, F2, SERPINC1
21vitamin k144 249.9F3, F2, SERPINC1
22heparinoids448.9F3, F2, SERPINC1
23fondaparinux448.9SERPINC1, F2, F3
24bivalirudin44 119.9F3, F2, SERPINC1
25phenprocoumon44 49 1110.9F3, F2, SERPINC1
26argatroban44 119.9F3, F2, SERPINC1
27hydroxyethyl starch448.9F3, F2, SERPINC1
28ppack448.9F3, F2, SERPINC1
29protamine sulfate448.9SERPINC1, F2, F3
30tranexamic acid44 119.8SERPINC1, F2, F3
31dabigatran448.8SERPINC1, F3
32epsilon aminocaproic acid448.8SERPINC1, F2, F3
33ristocetin448.8SERPINC1, F2, F3
34levonorgestrel44 59 28 1111.8F3, F2, SERPINC1
35coumarin44 2 49 2411.8F3, F2, SERPINC1
36desmopressin44 59 28 1111.8F3, F2, SERPINC1
37hirudin448.8SERPINC1, F2, F3
38protamine448.6F3, F2, SERPINC1
39dermatan sulfate448.5SERPINC1, F2, F3
40kininogen448.5SERPINC1, F2, F3, APOH
41prostacyclin448.4SERPINC1, F3, CRP, APOH
42tirofiban44 119.4SERPINC1, F2, F3, CRP
43abciximab44 119.4SERPINC1, F2, F3, CRP
44clopidogrel49 44 11 2411.4SERPINC1, F2, F3, CRP
45citrate448.3CRP, F3, F2, SERPINC1
46homocysteine44 249.0APOH, CRP, F3, F2, SERPINC1
47aspirin44 49 28 2411.0APOH, CRP, F3, F2, SERPINC1
48fibrinogen447.9APOH, CRP, F3, F2, SERPINC1
49alanine447.7SERPINC1, F2, F3, CRP, GAD1
50creatinine447.6APOH, GAD1, CRP, F3, F2, SERPINC1

GO Terms for genes affiliated with Peripheral Vertigo

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16Gene Ontology
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Cellular components related to Peripheral Vertigo according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056157.5SERPINC1, F2, F3, CRP, APOH

Biological processes related to Peripheral Vertigo according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of fibrinolysisGO:0519189.5F2, APOH
2positive regulation of blood coagulationGO:0301949.4F2, APOH
3blood coagulation, intrinsic pathwayGO:0075979.3APOH, F2
4acute-phase responseGO:0069539.0F2, CRP
5blood coagulationGO:0075968.5SERPINC1, F2, F3

Molecular functions related to Peripheral Vertigo according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protease bindingGO:0020209.1SERPINC1, F3
2protein bindingGO:0055156.8SERPINC1, F2, F3, CRP, GAD1, APOH

Products for genes affiliated with Peripheral Vertigo

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Peripheral Vertigo

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet