MCID: PRT070
MIFTS: 46

Peritoneal Carcinoma malady

Cancer diseases, Rare diseases categories
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Summaries for Peritoneal Carcinoma

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MalaCards based summary: Peritoneal Carcinoma, also known as malignant tumor of peritoneum, is related to ovarian cancer and lynch syndrome. An important gene associated with Peritoneal Carcinoma is CXCL10 (chemokine (C-X-C motif) ligand 10), and among its related pathways are Meiosis and Fanconi anemia pathway. The compounds 8-oxoguanine and daidzein have been mentioned in the context of this disorder. Affiliated tissues include lymph node, brain and breast, and related mouse phenotypes are limbs/digits/tail and digestive/alimentary.

Aliases & Classifications for Peritoneal Carcinoma

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Sources:
10DISEASES, 44Novoseek, 62UMLS
See all sources

Peritoneal Carcinoma, Aliases & Descriptions:

Name: Peritoneal Carcinoma 10
Malignant Tumor of Peritoneum 62
 
Carcinoma of Peritoneum 62
Peritoneal Cancer 44


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases


Related Diseases for Peritoneal Carcinoma

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Diseases in the Primary Peritoneal Carcinoma family:

Peritoneal Benign Neoplasm peritoneal carcinoma

Diseases related to Peritoneal Carcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 53)
idRelated DiseaseScoreTop Affiliating Genes
1ovarian cancer30.4ERCC1, BRCA1, BRCA2
2lynch syndrome30.3BRCA2, BRCA1
3fallopian tube cancer30.1BRCA2, BRCA1
4adenocarcinoma29.9ERCC1, CXCL10, BRCA1, BRCA2
5peritonitis11.1
6primary peritoneal carcinoma11.0
7breast-ovarian cancer, familial, 110.4BRCA2
8brca1 and brca2 hereditary breast and ovarian cancer10.2BRCA2, BRCA1
9bilateral breast cancer10.1BRCA2, BRCA1
10male breast cancer10.1BRCA1, BRCA2
11dysgerminoma10.1BRCA1, BRCA2
12ductal carcinoma in situ10.1BRCA1, BRCA2
13gynecomastia10.1BRCA2, BRCA1
14tuberculosis10.1
15bloom syndrome10.1BRCA2, BRCA1
16li-fraumeni syndrome10.1BRCA1, BRCA2
17aplastic anemia10.1BRCA2, BRCA1
18xeroderma pigmentosum10.1BRCA1, ERCC1
19fanconi's anemia10.1BRCA1, BRCA2
20multiple endocrine neoplasia10.0RET, BRCA2
21neurofibromatosis10.0RET, BRCA2
22autosomal dominant disease10.0BRCA1, RET
23ataxia telangiectasia10.0BRCA1, BRCA2
24ovarian serous carcinoma10.0
25lymphangitis10.0
26choroiditis10.0
27cervicitis10.0
28endometriosis10.0
29in situ carcinoma10.0
30paraneoplastic syndromes10.0
31endotheliitis10.0
32papillary carcinoma10.0BRCA2, RET
33endometrial carcinoma10.0BRCA1, BRCA2
34gastric cancer9.9
35liver cirrhosis9.9
36newcastle disease9.9
37wernicke-korsakoff syndrome9.9
38asbestosis9.9
39pleural cancer9.9
40bladder carcinoma9.9CXCL10, ERCC1, BRCA1
41pancreatic cancer9.9BRCA2, RET
42astrocytoma9.9BRCA1, ERCC1, CXCL10
43hodgkin's lymphoma9.9BRCA1, BRCA2
44chronic lymphocytic leukemia9.9BRCA2, ERCC1
45stomach cancer9.9ERCC1, BRCA2, BRCA1
46breast cancer9.9BRCA1, BRCA2, ERCC1
47colonic benign neoplasm9.8ERCC1, BRCA1, BRCA2
48melanoma9.8BRCA2, ERCC1, CXCL10
49colorectal cancer9.8BRCA2, BRCA1, ERCC1
50familial colorectal cancer9.8BRCA2, BRCA1, RET

Graphical network of the top 20 diseases related to Peritoneal Carcinoma:



Diseases related to peritoneal carcinoma

Symptoms for Peritoneal Carcinoma

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Drugs & Therapeutics for Peritoneal Carcinoma

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Drug clinical trials:

Search ClinicalTrials for Peritoneal Carcinoma

Search NIH Clinical Center for Peritoneal Carcinoma

Genetic Tests for Peritoneal Carcinoma

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Anatomical Context for Peritoneal Carcinoma

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MalaCards organs/tissues related to Peritoneal Carcinoma:

32
Lymph node, Brain, Breast, Eye, Ovary, Testes, Endothelial

Animal Models for Peritoneal Carcinoma or affiliated genes

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Publications for Peritoneal Carcinoma

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Articles related to Peritoneal Carcinoma:

(show top 50)    (show all 151)
idTitleAuthorsYear
1
Cytoreductive surgery under aminolevulinic Acid-mediated photodynamic diagnosis plus hyperthermic intraperitoneal chemotherapy in patients with peritoneal carcinomatosis from ovarian cancer and primary peritoneal carcinoma: results of a phase I trial. (25056850)
2014
2
Randomised phase II study of docetaxel plus vandetanib versus docetaxel followed by vandetanib in patients with persistent or recurrent epithelial ovarian, fallopian tube or primary peritoneal carcinoma: SWOG S0904. (24709487)
2014
3
A phase II study of ramucirumab (IMC-1121B) in the treatment of persistent or recurrent epithelial ovarian, fallopian tube or primary peritoneal carcinoma. (25016924)
2014
4
A phase II study of modified dose-dense paclitaxel and every 4-week carboplatin for the treatment of advanced-stage primary epithelial ovarian, fallopian tube, or peritoneal carcinoma. (23660691)
2013
5
Pegylated liposomal doxorubicin for platinum-resistant or refractory MA1llerian carcinoma (epithelial ovarian carcinoma, primary carcinoma of Fallopian tube and peritoneal carcinoma): A single-institutional experience. (23255889)
2013
6
Association between Rash and a Positive Drug Response Associated with Vinorelbine in a Patient with Primary Peritoneal Carcinoma. (24073344)
2013
7
Upper abdominal procedures in advanced stage ovarian or primary peritoneal carcinoma patients with minimal or no gross residual disease: an analysis of Gynecologic Oncology Group (GOG) 182. (23791702)
2013
8
A phase II trial of Sunitinib malate in recurrent and refractory ovarian, fallopian tube and peritoneal carcinoma. (22885865)
2013
9
The effect of age on first-line chemotherapy for epithelial ovarian cancer and primary peritoneal carcinoma. (23146339)
2013
10
Phase II evaluation of dasatinib in the treatment of recurrent or persistent epithelial ovarian or primary peritoneal carcinoma: a Gynecologic Oncology Group study. (22710075)
2012
11
A phase II study of a urokinase-derived peptide (A6) in the treatment of persistent or recurrent epithelial ovarian, fallopian tube, or primary peritoneal carcinoma: a Gynecologic Oncology Group study. (22446624)
2012
12
A phase II evaluation of lapatinib in the treatment of persistent or recurrent epithelial ovarian or primary peritoneal carcinoma: a gynecologic oncology group study. (22037316)
2012
13
Prognosis of primary peritoneal carcinoma: effect of cytoreductive surgery combined with neoadjuvant chemotherapy after laparoscopic diagnosis and evaluation: a multi-center trial. (22439406)
2012
14
Intravenous/intraperitoneal paclitaxel and intraperitoneal carboplatin in patients with epithelial ovarian, fallopian tube, or peritoneal carcinoma: a feasibility study. (22146766)
2012
15
An analysis of patients with bulky advanced stage ovarian, tubal, and peritoneal carcinoma treated with primary debulking surgery (PDS) during an identical time period as the randomized EORTC-NCIC trial of PDS vs neoadjuvant chemotherapy (NACT). (21917306)
2012
16
Primary peritoneal carcinoma in complete remission: a case report. (22199305)
2011
17
Peritoneal tuberculosis: a retrospective review of 20 cases and comparison with primary peritoneal carcinoma. (20973271)
2010
18
Methylation and protein expression of DNA repair genes: association with chemotherapy exposure and survival in sporadic ovarian and peritoneal carcinomas. (19602291)
2009
19
Phase II trial of single agent cetuximab in patients with persistent or recurrent epithelial ovarian or primary peritoneal carcinoma with the potential for dose escalation to rash. (19162309)
2009
20
A contemporary analysis of the ability of preoperative serum CA-125 to predict primary cytoreductive outcome in patients with advanced ovarian, tubal and peritoneal carcinoma. (19100916)
2009
21
RET/PTC rearrangement occurring in primary peritoneal carcinoma. (19147513)
2009
22
Primary peritoneal carcinoma: computed tomography and magnetic resonance findings. (18664839)
2008
23
Advanced primary peritoneal carcinoma: clinicopathological and prognostic factor analyses. (18543395)
2008
24
Paclitaxel, carboplatin and pegylated liposomal doxorubicin in ovarian and peritoneal carcinoma: a phase I study of the Gynecologic Oncology Group. (16959305)
2007
25
Colorectal resection in patients with ovarian and primary peritoneal carcinoma. (16730631)
2006
26
Primary peritoneal carcinoma in a UK cancer center: comparison with advanced ovarian carcinoma over a 5-year period. (16515579)
2006
27
Common polymorphism in interleukin 6 influences survival of women with ovarian and peritoneal carcinoma. (17023036)
2006
28
Primary peritoneal carcinoma: a rare neoplasm with pleomorphic trophoblastic morphology. (16907865)
2006
29
Safety and efficacy of thalidomide in recurrent epithelial ovarian and peritoneal carcinoma. (16828852)
2006
30
Phase II evaluation of 9-aminocamptothecin (9-AC, NSC #603071) in platinum-resistant ovarian and primary peritoneal carcinoma: a Gynecologic Oncology Group Study. (15589582)
2005
31
Is semen an etiologic factor in the development of primary peritoneal carcinoma and epithelial ovarian cancer? (15607552)
2005
32
Gemcitabine and cisplatin chemotherapy is an active combination in the treatment of platinum-resistant ovarian and peritoneal carcinoma. (15292718)
2004
33
Peritoneal carcinoma in women with genetic susceptibility: implications for Jewish populations. (15516851)
2004
34
Peritoneal carcinoma in a male patient. (12759547)
2003
35
A phase II study of docetaxel in paclitaxel-resistant ovarian and peritoneal carcinoma: a Gynecologic Oncology Group study. (12586591)
2003
36
Gemcitabine reverses cisplatin resistance: demonstration of activity in platinum- and multidrug-resistant ovarian and peritoneal carcinoma. (12504621)
2003
37
Fallopian tube and primary peritoneal carcinomas associated with BRCA mutations. (14615451)
2003
38
Axillary lymphadenopathy as the primary presentation of primary peritoneal carcinoma. (12592068)
2002
39
Positive emission tomography for evaluating a complete clinical response in patients with ovarian or peritoneal carcinoma: correlation with second-look laparotomy. (11426956)
2001
40
Extreme drug resistance assay and response to chemotherapy in patients with primary peritoneal carcinoma. (10738268)
2000
41
Clinical and biological effects of intraperitoneal injections of recombinant interferon-gamma and recombinant interleukin 2 with or without tumor-infiltrating lymphocytes in patients with ovarian or peritoneal carcinoma. (10873077)
2000
42
Detecting abnormal cells from primary serous peritoneal carcinoma by Pap smear. (10579010)
1999
43
A phase I trial of intravenous melphalan, paclitaxel, and cisplatin plus granulocyte-colony stimulating factor in patients with suboptimal advanced epithelial ovarian carcinoma or peritoneal carcinoma. (10590370)
1999
44
Solitary brain metastasis indicating recurrent primary peritoneal carcinoma. (10912420)
1999
45
Importance of lymph node metastases in primary peritoneal carcinoma. (9701204)
1998
46
Evidence that a "treatment-free interval of less than 6 months" does not equate with clinically defined platinum resistance in ovarian cancer or primary peritoneal carcinoma. (9692840)
1998
47
Extraovarian primary peritoneal carcinoma. (9644683)
1998
48
Two sequential studies for primary peritoneal carcinoma: induction with weekly cisplatin followed by either cisplatin-doxorubicin-cyclophosphamide or paclitaxel-cisplatin. (9367697)
1997
49
Primary peritoneal carcinoma: a treatable subset of patients with adenocarcinoma of unknown primary. (8602811)
1996
50
Surgically documented responses to paclitaxel and cisplatin in patients with primary peritoneal carcinoma. (8690292)
1996

Variations for Peritoneal Carcinoma

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Expression for genes affiliated with Peritoneal Carcinoma

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Expression patterns in normal tissues for genes affiliated with Peritoneal Carcinoma

Search GEO for disease gene expression data for Peritoneal Carcinoma.

Pathways for genes affiliated with Peritoneal Carcinoma

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Pathways related to Peritoneal Carcinoma according to GeneCards/GeneDecks:

(show all 12)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.3BRCA2, BRCA1
2
Show member pathways
9.3BRCA2, BRCA1
39.3BRCA1, BRCA2
4
Show member pathways
Signaling Pathways in Glioblastoma37
9.3BRCA1, BRCA2
59.3BRCA1, BRCA2
6
Show member pathways
9.3BRCA1, BRCA2
79.3BRCA1, BRCA2
8
Show member pathways
9.3BRCA1, BRCA2
9
Show member pathways
8.8BRCA2, BRCA1, ERCC1
10
Show member pathways
8.8ERCC1, BRCA1, BRCA2
118.8ERCC1, BRCA1, BRCA2
12
Show member pathways
8.8ERCC1, BRCA1, BRCA2

Compounds for genes affiliated with Peritoneal Carcinoma

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Compounds related to Peritoneal Carcinoma according to GeneCards/GeneDecks:

(show all 50)
idCompoundScoreTop Affiliating Genes
18-oxoguanine449.7BRCA2, BRCA1
2daidzein449.7BRCA2, BRCA1
3lycopene44 2410.7BRCA2, BRCA1
4vinorelbine44 50 1111.7BRCA1, ERCC1
5platinum44 5010.7ERCC1, BRCA1
6indole-3-carbinol449.7BRCA2, BRCA1
7chloroquine44 2 50 28 1113.7CXCL10, BRCA1
8methylmethanesulfonate449.7BRCA1, BRCA2
9benzo(a)pyrene449.7ERCC1, BRCA1
10oxaliplatin44 50 1111.7BRCA1, ERCC1
114-hydroxytamoxifen449.7BRCA2, BRCA1
12bleomycin44 1110.7BRCA1, BRCA2
13carboplatin44 50 1111.6ERCC1, BRCA1
14adpribose449.6BRCA2, BRCA1
15hydroxyurea44 50 1111.6BRCA1, BRCA2
16gemcitabine44 50 1111.6ERCC1, BRCA1
17lactacystin449.6ERCC1, BRCA1
18p003449.6BRCA2, BRCA1
19thymidylate449.6ERCC1, BRCA1
20p002449.5BRCA1, BRCA2
21resveratrol44 61 24 1112.5BRCA2, BRCA1
22adriamycin449.5BRCA1, BRCA2
23camptothecin44 61 1111.4BRCA1, BRCA2
24cyclophosphamide44 50 1111.3BRCA1, ERCC1
25glycerol44 24 1111.3ERCC1, BRCA1
26gold449.3CXCL10, BRCA1, BRCA2
27mitomycin c449.3ERCC1, BRCA1, BRCA2
28vincristine44 50 1111.3BRCA2, BRCA1, ERCC1
29docetaxel44 50 61 1112.2BRCA2, BRCA1, ERCC1
30cycloheximide449.2CXCL10, BRCA1, BRCA2
31methotrexate50 44 1111.2ERCC1, BRCA1, BRCA2
32etoposide44 50 61 1112.2ERCC1, BRCA1, BRCA2
33progesterone44 28 61 24 1113.2CXCL10, BRCA1, BRCA2
34paclitaxel44 50 1111.2ERCC1, BRCA1, BRCA2
35cisplatin44 50 61 1112.2ERCC1, BRCA1, BRCA2
36heparan sulfate44 2410.1CXCL10, RET
37folate449.0BRCA1, BRCA2
38adenine44 24 1111.0RET, CXCL10, BRCA1
39paraffin448.9RET, BRCA1, BRCA2
40testosterone44 61 24 1111.9RET, BRCA1, BRCA2
41alanine448.8RET, CXCL10, BRCA1
42thymidine44 249.8BRCA2, BRCA1, CXCL10, ERCC1
43estrogen448.8BRCA2, BRCA1, CXCL10, ERCC1
44atp44 289.6BRCA1, CXCL10, RET
45genistein44 28 61 2 24 1113.5BRCA2, BRCA1, CXCL10, RET
46vegf448.5BRCA1, CXCL10, RET, ERCC1
47retinoic acid44 249.5BRCA2, BRCA1, CXCL10, RET
48tyrosine448.4BRCA1, CXCL10, RET, ERCC1
49oligonucleotide448.4ERCC1, RET, BRCA1, BRCA2
50phosphatidylinositol448.0ERCC1, RET, CXCL10, BRCA1, BRCA2

GO Terms for genes affiliated with Peritoneal Carcinoma

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Cellular components related to Peritoneal Carcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nucleoplasmGO:0056548.8ERCC1, BRCA1, BRCA2

Biological processes related to Peritoneal Carcinoma according to GeneCards/GeneDecks:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1response to X-rayGO:0101659.6BRCA2, ERCC1
2response to gamma radiationGO:0103329.6BRCA2, CXCL10
3DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediatorGO:0069789.5BRCA1, BRCA2
4regulation of cell proliferationGO:0421279.4CXCL10, BRCA1
5double-strand break repair via homologous recombinationGO:0007249.2BRCA2, BRCA1
6nucleotide-excision repairGO:0062899.1ERCC1, BRCA2
7double-strand break repairGO:0063029.0ERCC1, BRCA1, BRCA2
8DNA repairGO:0062818.9ERCC1, BRCA1, BRCA2
9positive regulation of transcription, DNA-templatedGO:0458938.5RET, BRCA1, BRCA2

Molecular functions related to Peritoneal Carcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1single-stranded DNA bindingGO:0036979.1ERCC1, BRCA2
2protein bindingGO:0055157.5ERCC1, RET, CXCL10, BRCA1, BRCA2

Products for genes affiliated with Peritoneal Carcinoma

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  • Antibodies
  • Proteins
  • Lysates

Sources for Peritoneal Carcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet