MCID: PRT036
MIFTS: 67

Peritonitis

Categories: Rare diseases, Gastrointestinal diseases

Aliases & Classifications for Peritonitis

MalaCards integrated aliases for Peritonitis:

Name: Peritonitis 12 72 51 14 69
Retractile Mesenteritis 12 49 69
Sclerosing Mesenteritis 12 49 69
Peritoneal Retractile Mesenteritis 49 69
Acute Generalized Peritonitis 12 69
Primary Bacterial Peritonitis 12 69
Mesenteric Panniculitis 49 69
Idiopathic Sclerosing Mesenteritis 49
Liposclerotic Mesenteritis 49
Mesenteric Lipodystrophy 49
Mesenteric Lipogranuloma 49
Mesenteric Fibromatosis 49
Fibromatosis, Abdominal 69

Classifications:



Summaries for Peritonitis

NIH Rare Diseases : 49 Sclerosing mesenteritis is one of many terms that describes a spectrum of inflammatory disorders that affect the mesentery. The mesentery is the membrane that anchors the small intestine to the back of the abdominal wall. The condition mostly affects men between their 40s and 60s, but women and children can also be affected. It may result in a variety of symptoms including abdominal pain, nausea and vomiting, constipation or diarrhea, weight loss, and fever. Some people have an abdominal mass. The cause of the condition is poorly understood. Suggested possible causes have included previous abdominal surgery or trauma, autoimmunity, paraneoplastic syndromes, ischemic injury, and infection. Treatment depends on the symptoms in each person and may include the use of glucocorticoids, hormonal therapy (tamoxifen or progesterone), or other medications, either alone or in combination (i.e. glucocorticoids in combination with tamoxifen). Surgery may be needed for an obstruction, if present. Although there are case reports of patients with aggressive disease and fatalities, it appears that the condition usually remains stable or is slowly progessive. In some cases, the condition goes away on its own. Last updated: 7/24/2017

MalaCards based summary : Peritonitis, also known as retractile mesenteritis, is related to primary peritoneal carcinoma and tuberculous peritonitis. An important gene associated with Peritonitis is ALB (Albumin), and among its related pathways/superpathways are Innate Immune System and TGF-Beta Pathway. The drugs Ciprofloxacin and Enalapril have been mentioned in the context of this disorder. Affiliated tissues include liver, colon and kidney, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Disease Ontology : 12 A gastrointestinal system disease that involves inflammation of the peritoneum resulting from perforation of the gastrointestinal tract, which produces immediate chemical inflammation followed shortly by infection from intestinal organisms. Peritonitis can also result from appendicitis, diverticulitis, strangulating intestinal obstruction, pancreatitis, pelvic inflammatory disease, mesenteric ischemia, intraperitoneal blood, barium, or peritoneo-systemic shunts, drains, and dialysis catheters in the peritoneal cavity. The symptoms include abdominal pain and tenderness, fever, fluid in the abdomen, nausea, vomiting and low urine output.

Wikipedia : 72 Peritonitis is inflammation of the peritoneum, the lining of the inner wall of the abdomen and cover of... more...

Related Diseases for Peritonitis

Diseases related to Peritonitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 984)
# Related Disease Score Top Affiliating Genes
1 primary peritoneal carcinoma 34.2 CXCL8 IL10 MUC16
2 tuberculous peritonitis 33.6 ADA ALB CRP MUC16 TNF
3 familial mediterranean fever 33.0 CRP IL1B MEFV TNF
4 appendicitis 31.8 ALB CRP CXCL8 IL10 IL1B IL6
5 systemic onset juvenile idiopathic arthritis 31.7 IL1B MEFV TNF
6 endometriosis 31.1 CCL2 CXCL8 IL1B IL6 MUC16
7 end stage renal failure 30.7 ALB CRP IL6 TNF
8 endometritis 30.5 IL1B IL6 TNF
9 vaginitis 30.4 CXCL8 IL1B IL6
10 uremia 30.3 ALB B2M CRP
11 fasciitis 30.3 CXCL8 IL6 TNF
12 streptococcal toxic-shock syndrome 30.3 CXCL8 IL6 TNF
13 acute pancreatitis 30.3 CRP CXCL8 IL10 IL6
14 fascioliasis 30.2 ALB IL10 IL1B
15 echinococcosis 30.2 IL10 IL6 TNF
16 protein-energy malnutrition 30.2 ALB IL6 TNF
17 uremic pruritus 30.2 CRP IL1B IL6
18 mycobacterium chelonae 30.2 CXCL8 TLR2
19 abdominal tuberculosis 30.1 ADA ALB F2
20 alcoholic liver cirrhosis 30.0 ALB CXCL8 F2 TNF
21 hydronephrosis 30.0 ALB B2M CCL2
22 liver disease 30.0 ALB F2 IL6 TNF
23 spondyloarthropathy 30.0 IL10 IL6 TNF
24 colitis 29.9 CXCL8 IL10 IL1B IL6 TNF
25 compartment syndrome 29.9 ALB F2 TNF
26 diabetes mellitus 29.9 ALB CRP IL1B IL6 TNF
27 chronic kidney failure 29.9 ALB B2M CRP ICAM1 IL6
28 perinatal necrotizing enterocolitis 29.9 CRP CXCL8 IL1B IL6 TNF
29 mycobacterium abscessus 29.9 CXCL8 TLR2 TNF
30 pelvic inflammatory disease 29.9 CCL2 CRP TLR2
31 toxic shock syndrome 29.9 CXCL8 IL10 IL1B IL6 TNF
32 peripheral vascular disease 29.8 ALB CRP F2 IL6
33 pericardial effusion 29.8 ADA CRP IL6
34 glomerulonephritis 29.8 ALB CCL2 ICAM1 IL1B
35 duodenal ulcer 29.8 CXCL8 IL1B TNF
36 aortic aneurysm, familial abdominal, 1 29.8 CCL2 CRP IL6
37 hepatic encephalopathy 29.8 ALB F2 IL6 TNF
38 laryngitis 29.8 IL1B IL6 TNF
39 capillary leak syndrome 29.8 ALB CXCL8 IL6
40 purpura 29.8 CRP F2 TNF
41 mycobacterium tuberculosis 1 29.8 ADA CD69 IL10 TLR2 TNF
42 denture stomatitis 29.7 CCL2 CXCL8 IL6
43 neutrophil migration 29.7 CXCL8 ICAM1 ITGAM
44 endometrial disease 29.7 CXCL8 IL1B IL6
45 thrombocytosis 29.7 CRP F2 IL6
46 meningoencephalitis 29.7 ALB B2M IL6
47 relapsing fever 29.6 CRP MEFV TNF
48 haemophilus influenzae 29.6 CXCL8 IL1B TLR2 TNF
49 melioidosis 29.6 IL10 IL6 TLR2 TNF
50 arthritis 29.6 CCL2 CXCL8 IL10 IL1B IL6 TNF

Comorbidity relations with Peritonitis via Phenotypic Disease Network (PDN): (show all 13)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Acute Vascular Insufficiency of Intestine
Chronic Kidney Failure Deficiency Anemia
Familial Atrial Fibrillation Heart Disease
Intestinal Obstruction Intestinal Perforation
Paralytic Ileus Protein-Energy Malnutrition
Respiratory Failure

Graphical network of the top 20 diseases related to Peritonitis:



Diseases related to Peritonitis

Symptoms & Phenotypes for Peritonitis

GenomeRNAi Phenotypes related to Peritonitis according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.77 F2 ICAM1 IL10 IL1B TNF AQP1
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.77 F2 ICAM1 IL10 IL1B TNF AQP1

MGI Mouse Phenotypes related to Peritonitis:

43 (show all 11)
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.27 ADA AQP1 B2M CRP CXCL2 F2
2 hematopoietic system MP:0005397 10.25 ADA AQP1 B2M CD69 F2 ICAM1
3 homeostasis/metabolism MP:0005376 10.24 CRP F2 ICAM1 IL10 IL1B IL6
4 cellular MP:0005384 10.22 ADA ALB B2M CD69 ICAM1 IL10
5 immune system MP:0005387 10.2 CRP F2 ICAM1 IL10 IL1B IL6
6 digestive/alimentary MP:0005381 10.11 ADA ALB B2M F2 ICAM1 IL10
7 endocrine/exocrine gland MP:0005379 10.09 TLR2 TNF ADA ALB AQP1 B2M
8 integument MP:0010771 9.91 B2M F2 ICAM1 IL10 IL1B IL6
9 liver/biliary system MP:0005370 9.81 ADA ALB B2M IL10 IL6 LBP
10 neoplasm MP:0002006 9.56 IL6 TLR2 TNF ALB B2M ICAM1
11 skeleton MP:0005390 9.32 ADA AQP1 CD69 F2 IL10 IL1B

Drugs & Therapeutics for Peritonitis

Drugs for Peritonitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 254)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ciprofloxacin Approved, Investigational Phase 4,Phase 3,Phase 2 85721-33-1 2764
2
Enalapril Approved, Vet_approved Phase 4 75847-73-3 40466924 5362032
3
Enalaprilat Approved Phase 4 76420-72-9 6917719
4
Losartan Approved Phase 4 114798-26-4 3961
5
Spironolactone Approved Phase 4 1952-01-7, 52-01-7 5833
6
Hydralazine Approved Phase 4 86-54-4 3637
7
Propranolol Approved, Investigational Phase 4,Phase 3 525-66-6 4946
8
Angiotensin II Approved, Investigational Phase 4 68521-88-0, 4474-91-3, 11128-99-7 172198 65143
9
Azithromycin Approved Phase 4 83905-01-5 53477736 447043 55185
10
Amoxicillin Approved, Vet_approved Phase 4,Phase 3 26787-78-0 33613 2171
11
Vancomycin Approved Phase 4,Phase 2,Phase 3 1404-90-6 14969 441141
12
Metronidazole Approved Phase 4,Phase 3,Phase 2 443-48-1 4173
13
Norfloxacin Approved Phase 4,Phase 2,Phase 3 70458-96-7 4539
14
Imipenem Approved Phase 4,Phase 3 64221-86-9, 74431-23-5 104838
15
Cefotaxime Approved Phase 4,Phase 3 63527-52-6 5742673 456256
16
Cefazolin Approved Phase 4,Phase 3 25953-19-9 33255 656510
17
Benzocaine Approved, Investigational Phase 4 1994-09-7, 94-09-7 2337
18
Mupirocin Approved, Investigational, Vet_approved Phase 4 12650-69-0 446596
19
Menthol Approved Phase 4 2216-51-5 16666
20
Ceftazidime Approved Phase 4,Phase 2,Phase 3 72558-82-8, 78439-06-2 5481173
21
Cefoxitin Approved Phase 4,Phase 3 35607-66-0 441199
22
Ertapenem Approved, Investigational Phase 4,Phase 2 153832-46-3 150610
23
Heparin Approved, Investigational Phase 4,Phase 2 9005-49-6 46507594 772
24
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
25
Dipyridamole Approved Phase 4 58-32-2 3108
26
Carvedilol Approved, Investigational Phase 4 72956-09-3 2585
27
Warfarin Approved Phase 4 81-81-2 54678486 6691
28
Ceftriaxone Approved Phase 4,Phase 3 73384-59-5 5479530 5361919
29
Dexmedetomidine Approved, Vet_approved Phase 4 76631-46-4, 113775-47-6 5311068 56032 68602
30
Icodextrin Approved, Investigational Phase 4,Phase 2 337376-15-5
31
Minocycline Approved, Investigational Phase 4,Phase 3 10118-90-8 5281021
32
Lenograstim Approved, Investigational Phase 4,Phase 2,Phase 3 135968-09-1
33
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 2713 9552079
34
Ampicillin Approved, Vet_approved Phase 4 69-53-4 6249
35 Nadroparin Approved, Investigational Phase 4 9041-08-1
36
Sulbactam Approved Phase 4 68373-14-8
37
Cefepime Approved, Investigational Phase 4 88040-23-7 5479537
38
Tigecycline Approved Phase 4,Phase 3 220620-09-7 5282044
39
Acetylcysteine Approved, Investigational Phase 4,Phase 2,Phase 3 616-91-1 12035
40
Bacitracin Approved, Vet_approved Phase 4 1405-87-4 10909430 439542
41
Dalteparin Approved Phase 4 9005-49-6
42 Sultamicillin Approved, Investigational Phase 4 76497-13-7
43
Pentoxifylline Approved, Investigational Phase 4 6493-05-6 4740
44
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
45
Micafungin Approved, Investigational Phase 4 235114-32-6 477468 3081921
46
Teicoplanin Approved, Investigational Phase 4 61036-62-2
47
Caspofungin Approved Phase 4 162808-62-0, 179463-17-3 2826718 468682
48
Dalbavancin Approved, Investigational Phase 4 171500-79-1, 91097-81-3 122186
49 tannic acid Approved, Nutraceutical Phase 4
50 Clavulanic Acid Phase 4,Phase 3

Interventional clinical trials:

(show top 50) (show all 221)

# Name Status NCT ID Phase Drugs
1 Randomized Comparison of Two Albumin Administration Schedules for Spontaneous Bacterial Peritonitis (SBP) Unknown status NCT00761098 Phase 4 Standard Care;Experimental
2 Probiotics Use in the Chronic Peritoneal Dialysis Patients Unknown status NCT01076426 Phase 4 Pro-biotics
3 Antibiotics Versus Surgery in Acute Appendicitis Unknown status NCT01421901 Phase 4 Ertapenem
4 Topical Gentamicin Cream Versus Alternating Gentamicin and Mupirocin Cream in Peritoneal Dialysis Unknown status NCT00751374 Phase 4 gentamicin;gentamicin cream alternating with mupirocin cream
5 The Effect of Enalapril and Losartan on Peritoneal Membrane in Continuous Ambulatory Peritoneal Dialysis Patients Unknown status NCT01041963 Phase 4 Enalapril;Enalapril plus Losartan;Placebo
6 Extended Antibiotic Therapy in Postoperative of Laparoscopic Cholecystectomy in Acute Cholecystitis Unknown status NCT02057679 Phase 4 Amoxicillin clavulanic;Placebo
7 Comparison the Level of CTGF Protein and Related Cytokine in Pleural Effusion Unknown status NCT00313066 Phase 4
8 Empirical vs 2nd Line Antibiotic Therapy in Health-care Associated Infections in Cirrhosis Unknown status NCT01820026 Phase 4 Imipenem;Vancomycin;azithromycin;Cefotaxime;Amoxicillin
9 Prospective Comparison of Primary Abdominal Closure and Vacuum Assisted Laparostomy in Treatment of Severe Peritonitis Completed NCT01531543 Phase 4
10 Bacteria Endotoxin in Peritoneal Dialysis Effluent as a Predictor of Relapsing, Recurrent, and Repeat Peritonitis Completed NCT01817309 Phase 4
11 IV Antibiotics With Lavage for Severe PD Peritonitis Completed NCT02926846 Phase 4 Intravenous vancomycin & gentamicin with adjunctive lavage;Intraperitoneal vancomycin & gentamicin
12 Effect of Icodextrin on the Treatment Outcome of Peritoneal Dialysis Patients During Acute Peritonitis Completed NCT01044446 Phase 4 Icodextrin;glucose-based peritoneal dialysate
13 Comparing Cefepime Versus Cefazolin Plus Ceftazidime for CAPD-associated Peritonitis Completed NCT02872038 Phase 4 Cefepime;Cefazolin plus Ceftazidime
14 Norfloxacin Versus Ciprofloxacin for Spontaneous Bacterial Peritonitis (SBP) Prevention Completed NCT01542801 Phase 4 Norfloxacin;ciprofloxacin
15 Health Economic Assessment of Tygacil® in the Treatment of Secondary Peritonitis in Intensive Care Units (ICUs) Completed NCT00481962 Phase 4 Tygacil
16 Norfloxacin In The Primary Prophylaxis Of Spontaneous Bacterial Peritonitis Completed NCT00359853 Phase 4 Oral norfloxacin
17 Randomized Controlled Trial Comparing Residual Kidney Function in Patients Undergoing Three or Four Exchanges CAPD Completed NCT01637792 Phase 4
18 Comparison of Efficacy of Cefotaxime, Ceftriaxone, and Ciprofloxacin for the Treatment of SBP in Patients With LC Completed NCT01265173 Phase 4 Cefotaxime;Ceftriaxone;Ciprofloxacin
19 Open Label Trial to Establish the Equivalence Between ANDY-Disc® and Ultrabag® in Patients on CAPD. Completed NCT00255619 Phase 4
20 Beneficial Effect of Probiotics on Chronic Kidney Disease Completed NCT01391468 Phase 4
21 Study on B-blockers to Prevent Decompensation of Cirrhosis With HTPortal Completed NCT01059396 Phase 4 propranolol;carvedilol;placebo
22 Use of Ointments in Prevention of Catheter Related Infections in PD Completed NCT00400595 Phase 4 Mupirocin ointment;Polysporin Triple
23 Omega-3 Fatty Acids and Postoperative Complications After Colorectal Surgery Completed NCT00488904 Phase 4
24 Administration of pH-Neutral Peritoneal Dialysis Solutions Containing Lactate or Bicarbonate in Children Completed NCT01632046 Phase 4 lactate and bicarbonate buffered dialysis solutions
25 Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection Completed NCT00195351 Phase 4 tigecycline;ceftriaxone sodium + metronidazole
26 Dexmedetomidine for Sepsis in ICU Randomized Evaluation Trial Completed NCT01760967 Phase 4 Dexmedetomidine
27 T.E.A. Study Three Days Ertapenem Versus Three Days Ampicillin- Sulbactam Completed NCT00630513 Phase 4 Ertapenem;Ampicillin-Sulbactam
28 Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection (cIAI) Completed NCT00230971 Phase 4 tigecycline;ceftriaxone plus metronidazole
29 The Effect of Neutral Peritoneal Dialysis (PD) Solution With Minimal Glucose-Degradation-Product (GDP) on Fluid Status and Body Composition Completed NCT00966615 Phase 4
30 Warfarin Prevents Portal Vein Thrombosis in Patients After Laparoscopic Splenectomy and Azygoportal Disconnection Completed NCT02247414 Phase 4 Warfarin;Dipyridamole;Aspirin;Low Molecular Weight Heparin
31 Effect of Glucose Degradation Products (GDP) on Endothelial Dysfunction Completed NCT01315314 Phase 4 Balance, Fresenius Medical Care, Germany
32 Pharmacokinetic Study on Echinocandins for Patients With Septic Shock Following Secondary Peritonitis Recruiting NCT02805049 Phase 4 Echinocandins
33 PROPHYlactic Implantation of BIOlogic Mesh in Peritonitis (PROPHYBIOM) Recruiting NCT02277262 Phase 4
34 The Efficacy of Prolonged Antibiotic Therapy for the Prevention of Relapsing Peritonitis in Peritoneal Dialysis Patients With High Dialysis Effluent Bacterial DNA Fragment Levels Recruiting NCT02593201 Phase 4 Extended antibiotics (cefazolin or ceftazidime);Usual antibiotics (cefazolin or ceftazidime)
35 Evaluation of Intravenous and Intraperitoneal Pharmacokinetics of Dalbavancin in Peritoneal Dialysis Patients Recruiting NCT02940730 Phase 4 Dalbavancin via Intravenous Administration;Dalbavancin via Intraperitoneal Administration
36 FEcal Transplant, a Hope to Eradicate Colonization of Patient Harboring eXtreme Drug Resistant Bacteria? Recruiting NCT03029078 Phase 4 fecal microbiota transplant
37 G-CSF Plus NAC In Severe Alcoholic Hepatitis Recruiting NCT02971306 Phase 4 standard medical therapy;G-CSF;n-Acetylcysteine
38 Chlorhexidine Gluconate Versus Mupirocin Ointment in the Prevention of Peritoneal Dialysis-Related Infection Recruiting NCT02547103 Phase 4
39 Warfarin Prevents Portal Vein Thrombosis in Liver Cirrhotic Patients With Hypersplenism After Laparoscopic Splenectomy Recruiting NCT02238444 Phase 4 Warfarin;Dipyridamole;Aspirin;Low Molecular Weight Heparin
40 Initial Non-operative Treatment Strategy Versus Appendectomy Treatment Strategy for Simple Appendicitis in Children Recruiting NCT02848820 Phase 4 Augmentin + Gentamicin
41 The Effect of Branched-chain Amino Acid on the Improvement of Serum Albumin Level in Cirrhotic Patients With Ascites Recruiting NCT02755701 Phase 4 Branched-chain Amino Acid;Placebo
42 Straight Versus Coiled Peritoneal Dialysis Catheter for Peritoneal Dialysis Patients Active, not recruiting NCT02479295 Phase 4
43 Clinical, Inflammatory, and Economic Impact of Dextran 70 in Treating Spontaneous Bacterial Peritonitis Terminated NCT00570960 Phase 4 Dextran 70
44 The INFECIR-2 Albumin Prevention Study Terminated NCT02034279 Phase 4 Albumin
45 Method of Exit Site Care in Chronic Peritoneal Dialysis Patients Terminated NCT00416338 Phase 4
46 ICULIP, Influence of Two Lipid Emulsions in the Nosocomial Infection in Critical Patients Terminated NCT00396461 Phase 4 MCT/LCT (1:1);MCT/LCT/omega-3 (5:4:1)
47 Cefoperazone/Sulbactam In The Treatment Of Serious Intra-Abdominal And Hepatobiliary Infections. Withdrawn NCT00463762 Phase 4 CP-75385-02 Cefoperazone/sulbactam
48 Laparoscopic Peritoneal Lavage or Resection for Generalised Peritonitis for Perforated Diverticulitis Unknown status NCT01317485 Phase 3
49 Role of Probiotics in the Prevention of Spontaneous Bacterial Peritonitis in Cirrhotic Patients: A Randomized Placebo Control Trial Unknown status NCT00678613 Phase 2, Phase 3 Probiotics and Placebo;Probiotics and Norfloxacin
50 Moxifloxacin Plus Metronidazole Versus Piperacillin/Tazobactam for the Treatment of Patients With Intra-abdominal Abscesses Unknown status NCT00629135 Phase 3 Moxifloxacin/Metronidazole or Piperacillin/Tazobactam

Search NIH Clinical Center for Peritonitis

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Genetic Tests for Peritonitis

Anatomical Context for Peritonitis

MalaCards organs/tissues related to Peritonitis:

38
Liver, Colon, Kidney, Endothelial, Monocytes, Neutrophil, Small Intestine

Publications for Peritonitis

Articles related to Peritonitis:

(show top 50) (show all 4886)
# Title Authors Year
1
Outcome of autosomal dominant polycystic kidney disease patients on peritoneal dialysis: a national retrospective study based on two French registries (the French Language Peritoneal Dialysis Registry and the French Renal Epidemiology and Information Network). ( 29361078 )
2018
2
Mesenteric fibromatosis: a rare cause of peritonitis. ( 29424348 )
2018
3
A case of peritoneal malignant mesothelioma following radiation therapy for cervical cancer. ( 29435293 )
2018
4
COMPREHENSIVE APPROACH TO PERITONEAL DIALYSIS-RELATED PERITONITIS BY ENTERIC MICROORGANISMS. COMPARISON BETWEEN SINGLE ORGANISM AND POLYMICROBIAL INFECTIONS. ( 29386310 )
2018
5
Tracking Competent Host Defence to Chronic Inflammation: An In Vivo Model of Peritonitis. ( 29322409 )
2018
6
Eucalyptus globulus Inhibits Inflammasome-Activated Pro-Inflammatory Responses and Ameliorate Monosodium Urate-Induced Peritonitis in Murine Experimental Model. ( 29433388 )
2018
7
Atrial Fibrillation Characteristics in Patients on Haemodialysis vs. Peritoneal Dialysis. ( 29445225 )
2018
8
Diagnostic validity of flow cytometry vs manual counting of polymorphonuclear leukocytes in spontaneous bacterial peritonitis. ( 29383775 )
2018
9
Peritoneal sarcomatosis 5 years after laparoscopic morcellation of uterine leiomyoma. ( 29338993 )
2018
10
Double peritoneal fat flap in the treatment of an enterovesical fistula. ( 29256140 )
2018
11
A Rare Colonization in the Peritonitis Following Blunt Abdominal Trauma. ( 29449198 )
2018
12
Polymicrobial Anaerobic Bacteremia Caused by Butyricimonas virosa and Brachyspira pilosicoli in a Patient with Peritonitis following Intestinal Perforation. ( 29071824 )
2018
13
Is Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy Justified for Biphasic Variants of Peritoneal Mesothelioma? Outcomes from the Peritoneal Surface Oncology Group International Registry. ( 29260418 )
2018
14
Outcomes of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for peritoneal mesothelioma and predictors of survival. ( 29431036 )
2018
15
Multicenter Clinicopathological Study of High-Grade Serous Carcinoma Presenting as Primary Peritoneal Carcinoma. ( 29324533 )
2018
16
Management of neonatal spontaneous intestinal perforation by peritoneal needle aspiration. ( 29120457 )
2018
17
A retrospective study of the neuropathology and diagnosis of naturally occurring feline infectious peritonitis. ( 29411701 )
2018
18
A case of twin IVF pregnancy complicated with sclerosing encapsulating peritonitis diagnosed at caesarean delivery. ( 29430973 )
2018
19
OUTCOMES OF<i>ACINETOBACTER</i>PERITONITIS IN PERITONEAL DIALYSIS PATIENTS: A MULTICENTER REGISTRY ANALYSIS. ( 29437143 )
2018
20
A RETROSPECTIVE ANALYSIS OF ETIOLOGY AND OUTCOMES OF REFRACTORY CAPD PERITONITIS IN A TERTIARY CARE CENTER FROM NORTH INDIA. ( 29386307 )
2018
21
Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT. ( 29443079 )
2018
22
Unusual Cause of Peritonitis in Peritoneal Dialysis: Streptococcus vestibularis. ( 29377513 )
2018
23
Iatrogenic peritonitis following an incident during ablation of a pedicle screw. ( 29355744 )
2018
24
Expression of microRNAs in the ascites of patients with peritoneal carcinomatosis and peritonitis. ( 29360196 )
2018
25
Immunohistochemistry in Peritoneal Mesothelioma: A Single-Center Experience of 244 Cases. ( 29048219 )
2018
26
Current Management and Future Opportunities for Peritoneal Metastases: Peritoneal Mesothelioma. ( 29423664 )
2018
27
Comparison of the performance of laboratory tests in the diagnosis of feline infectious peritonitis. ( 29429403 )
2018
28
Benign multicystic peritoneal mesothelioma treated with laparoendoscopic single site surgery: a case report and review of the literature. ( 29372166 )
2018
29
Comment to: Pre-peritoneal local anaesthetic does not reduce post-operative pain in laparoscopic total extra-peritoneal inguinal hernia repair: double-blinded randomized controlled trial. Kulasegaran S, Rohan M, Pearless L, Hulme-Moir M. ( 29356910 )
2018
30
Letter: the efficacy and safety of rifaximin for the prophylaxis of spontaneous bacterial peritonitis in cirrhotic patients. ( 29417632 )
2018
31
Negative regulation of Nod-like receptor protein 3 inflammasome activation by T cell Ig mucin-3 protects against peritonitis. ( 28799242 )
2018
32
Spontaneous bacterial peritonitis due to Helicobacter pylori in a cirrhotic patient with human immunodeficiency virus and hepatitis C virus coinfection. ( 29429754 )
2018
33
Peritoneal inflammation and fibrosis in C-reactive protein transgenic mice undergoing peritoneal dialysis solution treatment. ( 26857687 )
2017
34
Peritoneal metastasis from pancreatic cancer treated with pressurized intraperitoneal aerosol chemotherapy (PIPAC). ( 28516306 )
2017
35
Significant Clinical Benefit of Pemetrexed-based Chemotherapy for Advanced Diffuse Malignant Peritoneal Mesothelioma: A Case Presentation. ( 28469343 )
2017
36
Transgenic Mice Expressing Human Proteinase 3 Exhibit Sustained Neutrophil-Associated Peritonitis. ( 29079698 )
2017
37
A loop of cancer-stroma-cancer interaction promotes peritoneal metastasis of ovarian cancer via TNFI+-TGFI+-EGFR. ( 28166193 )
2017
38
A Diagnostic Dilemma of Recurrent Disseminated Peritoneal Leiomyomatosis with Hypertrophied Omental Vessels: Imaging and Embolization of Omental Branches with Positive Outcome. ( 28251003 )
2017
39
Tuberculous peritonitis in the first trimester of pregnancy. ( 28344965 )
2017
40
Presentation of a malignant peritoneal mesothelioma in the forma of rough hepatic calcifications. ( 28480727 )
2017
41
Tuberculous Peritonitis. ( 28185616 )
2017
42
Concerns Regarding ISPD Recommendations for Peritonitis in Relation to Imipenem/Cilastatin-In Reply. ( 28931702 )
2017
43
Hydrocele Caused by Peritoneal Fluid Leakage Through Inguinal Canal. ( 28512168 )
2017
44
Endomyocardial fibrosis in a context of peritonitis. ( 28977410 )
2017
45
Innovations in Treatment Delivery, Risk of Peritonitis, and Patient Retention on Peritoneal Dialysis. ( 28066919 )
2017
46
Pasteurella multocida Bacteremia and Peritonitis in a Patient With Cirrhosis: A Life-Threatening Case From a Prick of a Cactus. ( 28890902 )
2017
47
Intestinal goblet cell carcinoid presenting with recurrent sterile peritonitis in a patient on peritoneal dialysis: a case report. ( 28193185 )
2017
48
The histone demethylase KDM4B regulates peritoneal seeding of ovarian cancer. ( 27869162 )
2017
49
Prophylaxis of lymphocele formation after kidney transplantation via peritoneal fenestration: aA systematic review. ( 28295643 )
2017
50
DDR2 Expression Is Associated with a High Frequency of Peritoneal Dissemination and Poor Prognosis in Colorectal Cancer. ( 28476831 )
2017

Variations for Peritonitis

Expression for Peritonitis

Search GEO for disease gene expression data for Peritonitis.

Pathways for Peritonitis

Pathways related to Peritonitis according to GeneCards Suite gene sharing:

(show top 50) (show all 63)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
14.12 B2M CCL2 CRP CXCL2 CXCL8 ICAM1
2
Show member pathways
13.61 CCL2 CXCL8 F2 ICAM1 IL10 IL1B
3
Show member pathways
13.5 CCL2 CXCL2 CXCL8 IL10 IL1B IL6
4
Show member pathways
13.47 B2M CCL2 CXCL2 CXCL8 ICAM1 IL10
5
Show member pathways
13.34 CCL2 CXCL2 CXCL8 IL10 IL1B IL6
6
Show member pathways
13.09 CCL2 CXCL2 CXCL8 IL1B IL6 MEFV
7
Show member pathways
12.96 B2M CXCL8 ICAM1 IL10 IL1B IL6
8
Show member pathways
12.91 CCL2 CXCL8 ICAM1 IL1B IL6 TLR2
9
Show member pathways
12.7 CCL2 F2 IL10 IL1B IL6 TNF
10
Show member pathways
12.68 CXCL2 CXCL8 ICAM1 IL6 TLR2 TNF
11 12.68 B2M CCL2 IL10 IL1B TLR2 TNF
12
Show member pathways
12.66 IL10 IL1B IL6 TLR2 TNF
13
Show member pathways
12.63 CCL2 CXCL8 IL10 IL1B IL6 LBP
14
Show member pathways
12.47 CCL2 CXCL2 CXCL8 IL1B IL6 TLR2
15
Show member pathways
12.38 CXCL8 IL1B IL6 LBP TNF
16
Show member pathways
12.37 IL10 IL1B ITGAM TLR2 TNF
17
Show member pathways
12.37 ALB CCL2 CRP F2 ICAM1 IL1B
18 12.34 IL10 IL1B IL6 ITGAM LBP TLR2
19
Show member pathways
12.33 CXCL8 IL1B IL6 LBP TLR2 TNF
20
Show member pathways
12.31 CXCL8 IL6 TLR2 TNF
21
Show member pathways
12.29 CCL2 CXCL2 CXCL8 F2 ICAM1 ITGAM
22 12.29 CXCL8 IL10 IL1B IL6 TNF
23
Show member pathways
12.28 CXCL8 IL10 IL1B IL6 TNF
24 12.16 CCL2 ICAM1 IL1B TNF
25 12.13 CD69 IL10 IL6 ITGAM TNF
26 12.1 CCL2 CXCL2 ICAM1 IL1B IL6 TNF
27
Show member pathways
12.07 IL10 IL1B IL6 TLR2 TNF
28 12.06 CCL2 CXCL8 ICAM1 IL1B IL6 TNF
29 12.03 CXCL2 CXCL8 ICAM1 IL1B LBP TNF
30 12 AQP1 CCL2 CXCL2 CXCL8 ICAM1 IL1B
31 11.99 IL1B IL6 ITGAM TNF
32 11.98 CXCL2 CXCL8 IL1B IL6 LBP
33
Show member pathways
11.97 CXCL8 ICAM1 IL6 LBP
34 11.93 CXCL8 IL10 IL1B IL6 ITGAM TLR2
35 11.9 IL10 IL1B ITGAM TNF
36 11.9 IL10 IL1B IL6 ITGAM TNF
37 11.87 CXCL8 IL10 IL1B IL6 ITGAM TNF
38 11.87 CCL2 CXCL8 ICAM1 IL1B IL6 TLR2
39 11.87 CCL2 CXCL8 ICAM1 IL10 IL1B IL6
40 11.85 ICAM1 IL10 IL6 TLR2 TNF
41 11.82 CXCL8 ICAM1 IL6
42 11.75 CCL2 CXCL2 CXCL8 IL1B IL6 TNF
43
Show member pathways
11.73 CXCL2 CXCL8 ICAM1 IL1B IL6 TNF
44 11.68 CCL2 IL1B ITGAM TLR2 TNF
45 11.65 ICAM1 IL10 ITGAM
46 11.65 ICAM1 IL6 ITGAM TNF
47 11.55 IL1B IL6 TNF
48 11.54 CXCL8 ICAM1 ITGAM
49 11.54 CXCL2 CXCL8 IL1B IL6 ITGAM TLR2
50 11.5 IL10 IL1B IL6 TNF

GO Terms for Peritonitis

Cellular components related to Peritonitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.97 ALB B2M CCL2 CRP CXCL2 CXCL8
2 cell surface GO:0009986 9.8 ADA B2M ICAM1 ITGAM LBP TLR2
3 extracellular space GO:0005615 9.53 ADA ALB B2M CCL2 CRP CXCL2
4 external side of plasma membrane GO:0009897 9.5 ADA B2M CD69 F2 ICAM1 ITGAM
5 extracellular exosome GO:0070062 10.02 ALB AQP1 B2M CRP F2 ICAM1

Biological processes related to Peritonitis according to GeneCards Suite gene sharing:

(show all 48)
# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.99 ALB B2M F2 IL6
2 leukocyte migration GO:0050900 9.97 F2 ICAM1 IL1B ITGAM TNF
3 immune response GO:0006955 9.97 B2M CCL2 CXCL2 CXCL8 IL10 IL1B
4 response to lipopolysaccharide GO:0032496 9.95 CXCL2 ICAM1 IL10 IL1B LBP TLR2
5 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.93 ICAM1 IL1B IL6 TLR2 TNF
6 positive regulation of DNA binding transcription factor activity GO:0051091 9.89 IL10 IL1B IL6 TNF
7 defense response to Gram-positive bacterium GO:0050830 9.89 CRP IL6 LBP TLR2 TNF
8 cellular response to organic cyclic compound GO:0071407 9.87 CCL2 IL1B TNF
9 cellular response to interleukin-1 GO:0071347 9.87 CCL2 CXCL8 ICAM1
10 chemokine-mediated signaling pathway GO:0070098 9.87 CCL2 CXCL2 CXCL8
11 response to insulin GO:0032868 9.86 ICAM1 IL10 TLR2
12 neutrophil chemotaxis GO:0030593 9.85 CCL2 CXCL8 IL1B
13 response to glucocorticoid GO:0051384 9.85 IL10 IL6 TNF
14 humoral immune response GO:0006959 9.84 CCL2 IL6 TNF
15 protein kinase B signaling GO:0043491 9.81 CCL2 IL1B TNF
16 acute-phase response GO:0006953 9.81 CRP F2 IL6 LBP
17 positive regulation of nitric oxide biosynthetic process GO:0045429 9.8 ICAM1 IL1B TNF
18 positive regulation of neutrophil chemotaxis GO:0090023 9.77 CXCL2 CXCL8 LBP
19 positive regulation of interleukin-6 production GO:0032755 9.77 IL1B IL6 LBP TLR2 TNF
20 positive regulation of NF-kappaB import into nucleus GO:0042346 9.76 IL1B TLR2 TNF
21 positive regulation of interleukin-8 production GO:0032757 9.76 IL1B LBP TLR2 TNF
22 embryonic digestive tract development GO:0048566 9.74 ADA CXCL8 TNF
23 negative regulation of growth of symbiont in host GO:0044130 9.73 IL10 LBP TNF
24 positive regulation of chemokine production GO:0032722 9.73 IL6 LBP TLR2 TNF
25 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.72 IL10 IL1B TNF
26 negative regulation of interleukin-12 production GO:0032695 9.7 IL10 MEFV
27 PERK-mediated unfolded protein response GO:0036499 9.7 CCL2 CXCL8
28 cellular response to lipoteichoic acid GO:0071223 9.7 LBP TLR2
29 negative regulation of lipid storage GO:0010888 9.7 CRP IL6 TNF
30 cellular response to lipopolysaccharide GO:0071222 9.7 CCL2 CXCL8 ICAM1 IL10 IL6 LBP
31 opsonization GO:0008228 9.68 CRP LBP
32 positive regulation of chemokine biosynthetic process GO:0045080 9.67 IL1B TNF
33 endothelial cell apoptotic process GO:0072577 9.67 IL10 TNF
34 regulation of establishment of endothelial barrier GO:1903140 9.66 IL1B TNF
35 positive regulation of leukocyte adhesion to vascular endothelial cell GO:1904996 9.65 ICAM1 TNF
36 negative regulation of cytokine secretion involved in immune response GO:0002740 9.65 IL10 TNF
37 lipopolysaccharide-mediated signaling pathway GO:0031663 9.65 CCL2 IL1B LBP TLR2 TNF
38 positive regulation of STAT protein import into nucleus GO:2000366 9.64 F2 IL6
39 positive regulation of fever generation GO:0031622 9.64 IL1B TNF
40 sequestering of triglyceride GO:0030730 9.62 IL1B TNF
41 receptor biosynthetic process GO:0032800 9.61 IL10 TNF
42 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.61 IL1B TNF
43 response to molecule of bacterial origin GO:0002237 9.35 B2M CXCL2 CXCL8 IL10 TLR2
44 inflammatory response GO:0006954 9.32 CCL2 CRP CXCL2 CXCL8 IL10 IL1B
45 negative regulation of cell proliferation GO:0008285 10.08 CXCL8 IL10 IL1B IL6 TLR2
46 positive regulation of gene expression GO:0010628 10.05 CRP IL1B IL6 TLR2 TNF
47 response to drug GO:0042493 10.02 ADA AQP1 B2M ICAM1 IL10
48 regulation of receptor activity GO:0010469 10.01 CCL2 CXCL2 CXCL8 F2 IL10 IL1B

Molecular functions related to Peritonitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.96 ADA ALB AQP1 B2M CCL2 CD69
2 chemokine activity GO:0008009 9.43 CCL2 CXCL2 CXCL8
3 lipopolysaccharide binding GO:0001530 9.33 F2 LBP TLR2
4 lipopeptide binding GO:0071723 9.32 LBP TLR2
5 cytokine activity GO:0005125 9.17 CCL2 CXCL2 CXCL8 IL10 IL1B IL6

Sources for Peritonitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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