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Peritonitis malady
18 drugs, 608 genes, 20 tissues, 984 related diseases, 28 phenotypes, 1646 articles, clinical trials.

Summaries for Peritonitis

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6Disease Ontology, 30NIH Rare Diseases, 44Wikipedia, 22MalaCards
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Disease Ontology: A gastrointestinal system infectious disease that involves inflammation of the peritoneum resulting from perforation of the gastrointestinal tract, which produces immediate chemical inflammation followed shortly by infection from intestinal organisms. peritonitis can also result from appendicitis, diverticulitis, strangulating intestinal obstruction, pancreatitis, pelvic inflammatory disease, mesenteric ischemia, intraperitoneal blood, barium, or peritoneo-systemic shunts, drains, and dialysis catheters in the peritoneal cavity. the symptoms include abdominal pain and tenderness, fever, fluid in the abdomen, nausea, vomiting and low urine output.6

MalaCards: Peritonitis, also known as retractile mesenteritis, is related to carcinoma and pancreatitis. An important gene associated with Peritonitis is MUC16 (mucin 16, cell surface associated), and among its related pathways are Rho Family GTPases and Akt Signaling. The drugs meropenem and ceftriaxone sodium and the compounds serine and creatinine have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, lymph node and brain, and related mouse phenotypes are homeostasis/metabolism and mortality/aging.

NIH Rare Diseases: Sclerosing mesenteritis is one of many terms used to describe a spectrum of chronic inflammatory diseases affecting the small bowel mesentery, the membrane that anchors the small intestine to the back of the abdominal wall.  The cause of this condition is unknown. The most common symptom is abdominal pain or a palpable abdominal mass. Click here to view an illustration of the small intestine.30

Wikipedia: Peritonitis is an inflammation of the peritoneum, the thin tissue that lines the inner wall of the...44 more...

Aliases & Descriptions for Peritonitis

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6Disease Ontology, 30NIH Rare Diseases, 8DISEASES, 32Novoseek , 43UMLS, 40SNOMED-CT, 19ICD9CM
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Aliases & Descriptions:

peritonitis 6 8 32 43
retractile mesenteritis 6 30 43
acute generalized peritonitis 6 43
sclerosing mesenteritis 6 30
acute generalized peritonitis (disorder) 6
primary bacterial peritonitis (disorder) 6
retractile mesenteritis (disorder) 6
peritoneal retractile mesenteritis 30
idiopathic sclerosing mesenteritis 30
spontaneous bacterial peritonitis 6
primary bacterial peritonitis 43
liposclerotic mesenteritis 30
mesenteric lipogranuloma 30
mesenteric lipodystrophy 30
mesenteric fibromatosis 30
mesenteric panniculitis 30

External Ids:

ICD9CM19 567.8, 567.89

Related Diseases for Peritonitis

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13GeneCards, 14GeneDecks
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Diseases related to peritonitis by text searches and GeneDecks gene sharing:

(show top 50)    (show all 981)
idRelated DiseaseScoreTop Affiliating Genes
1carcinoma83.1PIK3C2A, LRP1, LRPAP1, PDE3B, REG1A, REG4
2pancreatitis65.5PIK3C2A, LRG1, LRP1, PDE3B, REG1A, REG4
3adenocarcinoma61.3PIK3C2A, LRG1, LRP1, NCR2, PDE2A, REG1A
4prostatitis60.4PIBF1, PIK3C2A, LRP1, REG4, RELA, RELB
5gastric cancer60.1REG1A, REG4, RELA, KIT, VWF, VTN
6leukemia58.1PIBF1, PIK3C2A, LRP1, LRPAP1, COG2, NCR1
7melanoma57.8PIK3C2A, LRP1, PDE3B, RELA, RELB, RET
8ovarian cancer57.4LRP1, RELA, RELB, SGK1, KIT, KITLG
9colorectal cancer56.2LRPAP1, COG2, NCR1, REG1A, REG4, RELB
10fibrosis55.7LRG1, LRP1, REG1A, RELA, REN, SGK1
11endometriosis54.0PIBF1, RELA, CNTF, KIR2DL1, KIR2DL3, KITLG
12atherosclerosis54.0PIK3C2A, LRP1, LRPAP1, COG2, REG1A, REN
13cholesterol51.2PIK3C2A, LRP1, LRPAP1, COG2, PDE3B, REG1A
14hepatocellular carcinoma51.1REG1A, RELA, RELB, RET, KIT, KIR3DL1
15ovarian carcinoma49.3RELA, KIT, VTN, PCNA, RBP4, SELL
16thyroiditis49.3PIK3C2A, LRP1, LRPAP1, COG2, RELA, REN
17pneumonia48.6PIK3C2A, COG2, RELA, VTN, RBP4, SELE
18hypoxia48.5PIK3C2A, LRP1, RELA, REN, RET, KIT
19tuberculosis48.1NCR1, PDE3B, RELA, RELB, KIR2DL1, GC
20cervicitis47.5NCR1, NCR2, RELA, REN, RET, KIT
21colon cancer47.2PDE2A, REG1A, REG4, RELA, VWF, PCNA
22nephropathy45.8LRG1, LRP1, LRPAP1, COG2, REG1A, RELA
23sepsis45.0VTN, RBP4, SELE, SELL, SELP, SERPINC1
24infertility44.2PIK3C2A, SGK1, KIT, KIR2DL1, KIR2DL3, KITLG
25diabetes mellitus43.4PIK3C2A, COG2, PDE3B, REG1A, REN, RET
26hypertension43.4PIK3C2A, LRG1, LRP1, COG2, PDE3B, REN
27anemia42.8RELA, REN, SGK1, KIT, KITLG, VWF
28colon carcinoma40.9KIT, KITLG, VTN, SELE, SELL, SELP
29sarcoma40.5PIK3C2A, RELA, RELB, REN, RET, KIT
30insulin resistance39.7LRP1, COG2, PDE3B, RELA, REN, SGK1
31peritoneal carcinoma39.5RET, BRCA1, BRCA2, SCARA3, MUC16, SAR1B
32epithelial ovarian cancer39.4RELA, SERPINB2, SERPINE1, VIM, BRCA1, BRCA2
33influenza39.3PIK3C2A, NCR1, NCR2, RELA, KIR2DL1, VTN
34meningitis39.1PIK3C2A, PCNA, SELE, SELL, VIM, VEGFA
35acute pancreatitis38.4PIK3C2A, REG1A, VWF, SELE, SELP, SERPINC1
36endometrial carcinoma38.1PIK3C2A, LRP1, LRPAP1, RELA, KIT, KIR2DL3
37nephrotic syndrome38.0PIK3C2A, RELA, REN, KITLG, VWF, VTN
38liver cirrhosis37.9REN, VTN, RBP4, SERPINC1, SERPINF2, SERPINB2
39inflammatory bowel disease37.4REG4, SELE, SELL, SELP, SELPLG, NAGLU
40familial mediterranean fever37.4KIR2DL1, KIR2DL3, KIR3DL1, SELL, SELP, SERPINC1
41renal cell carcinoma37.3RELA, RET, KIT, PCNA, SELP, SETD2
42appendicitis37.0LRG1, SERPINE1, RARS, LCAT, LCN2, LACTB
43gonococcal synovitis36.6LRP1, PDE3B, REG1A, RELA, RELB, SGK1
44blindness36.4PIBF1, PIK3C2A, COG2, REN, CNTF, VWF
45malignant peritoneal mesothelioma36.3VIM, RAB25, BIRC5, CLDN15, CLDN3, MUC1
46hyperglycemia35.8PIK3C2A, COG2, PDE2A, SGK1, VWF, VTN
47immunodeficiency35.6KIR3DL1, SELL, BPI, MYD88, BMP6, S100A12
48septic shock35.4PIK3C2A, SELE, SELL, SERPINC1, SERPINE1, BPI
49homocysteine35.3PIK3C2A, COG2, RELA, REN, VWF, PCNA
50sickle cell disease35.0VWF, RBP4, SELE, SELL, SELP, SERPINE1

Graphical network of the top 20 diseases related to peritonitis:



Graphical network of diseases related to peritonitis

Clinical Features for Peritonitis

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Drugs & Therapeutics for Peritonitis

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4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials, 43UMLS, 28NDF-RT
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Approved drugs:

Search CenterWatch for peritonitis

Drug clinical trials:

Search ClinicalTrials for peritonitis

Search NIH Clinical Center for peritonitis

Search CenterWatch for peritonitis

Inferred drug relations via UMLS/NDF-RT:

43 28 albumin,aggregated, albumin,egg, albumin,human, albumin,human inj [va product], albumin,microsphere human serum, amphotericin b, amphotericin b cholesteryl sulfate, amphotericin b lipid complex, amphotericin b liposome, cefotaxime, cefotaxime sodium, cefotetan, cefotetan disodium, cefoxitin, cefoxitin sodium, ceftriaxone, ceftriaxone sodium, meropenem

Genetic Tests for Peritonitis

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Anatomical Context for Peritonitis

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22MalaCards
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MalaCards organs/tissues related to peritonitis:

22
Bone marrow, Lymph node, Brain, Heart, Smooth muscle, Small intestine, Colon, Adipocyte, Kidney, Liver, Lung, Thyroid, Ovary, Prostate, Monocytes, Nk cells, T cells, B cells, Endothelial, Appendix

Phenotypes for genes affiliated with Peritonitis

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25MGI
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MGI Mouse Phenotypes related to peritonitis:

25 (show all 28)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1homeostasis/metabolism phenotypeMP:000537625.1PIK3C2A, LRP1, LRPAP1, PDE3B, REG1A, RELA
2mortality/agingMP:001076823.4PIK3C2A, LRP1, LRPAP1, NCR1, PDE2A, RELA
3cellular phenotypeMP:000538422.8RELA, RELB, RET, CNTF, KIT, KITLG
4cardiovascular system phenotypeMP:000538521.2LRP1, RELA, RELB, REN, RET, KIT
5immune system phenotypeMP:000538720.1LRP1, RELB, REN, CNTF, KIT, VWF
6growth/size phenotypeMP:000537819.4PIK3C2A, LRP1, PDE3B, RELA, RELB, REN
7normal phenotypeMP:000287318.3LRP1, LRPAP1, NCR1, RELA, REN, RET
8hematopoietic system phenotypeMP:000539718.2NCR1, CNTF, KIT, PCNA, SERPINB2, BRCA1
9skeleton phenotypeMP:000539016.8LRP1, RELA, KIT, KITLG, GC, NAGLU
10digestive/alimentary phenotypeMP:000538116.4RELB, RET, KIT, KITLG, VWF, SERPINF1
11behavior/neurological phenotypeMP:000538615.7LRP1, RELB, REN, CNTF, KIT, SELE
12integument phenotypeMP:001077115.7PDE3B, RELA, RELB, KIT, KITLG, SELP
13tumorigenesisMP:000200615.6RET, KIT, KITLG, SELL, SERPINE1, BRCA1
14reproductive system phenotypeMP:000538915.1LRPAP1, REG1A, REN, RET, SFRP2, RBP4
15embryogenesis phenotypeMP:000538014.9RET, KIT, SFRP2, SERPINC1, SETD2, VIM
16vision/eye phenotypeMP:000539114.7RELA, KIT, KITLG, RBP4, SELE, SELP
17muscle phenotypeMP:000536914.5LRP1, RELA, RELB, REN, RET, CNTF
18endocrine/exocrine gland phenotypeMP:000537914.5LRPAP1, REG1A, RELB, RET, SFRP2, SELL
19nervous system phenotypeMP:000363114.4LRP1, LRPAP1, RELA, REN, CNTF, KIT
20no phenotypic analysisMP:000301214.3RET, SGK1, SFRP2, PCNA, VEGFA, VCAM1
21renal/urinary system phenotypeMP:000536713.9LRPAP1, REN, RET, SGK1, KIT, SELP
22liver/biliary system phenotypeMP:000537013.5RELB, KIT, SERPINC1, VHL, VEGFA, LPL
23limbs/digits/tail phenotypeMP:000537113.5RELA, RELB, RET, KIT, KITLG, SFRP2
24respiratory system phenotypeMP:000538813.1RELB, RET, SELL, SELP, BRCA1, LPL
25adipose tissue phenotypeMP:000537512.8PIK3C2A, LRP1, PDE3B, SERPINE1, BRCA1, LPL
26craniofacial phenotypeMP:000538212.1KIT, KITLG, NAGLU, UGDH, LBR, T
27hearing/vestibular/ear phenotypeMP:000537711.1KIT, KITLG, NAGLU, VDR, MYD88, BMP7
28other phenotypeMP:000539511.1LRPAP1, RELB, SERPINH1, RARA, KDR, LEPR

Publications for genes affiliated with Peritonitis

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35PubMed
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Articles related to peritonitis:

(show top 50)    (show all 1646)
idTitleAuthorsYearAffiliating Genes
1Intra-peritoneal interleukin-6 system is a potent det erminant of the baseline peritoneal solute transport in incident peritoneal dia lysis patients. (20061317)Oh K.H.... Ahn C.2010IL6, CCL2, ANGPT2
2Impact of systemic and local peritoneal inflammation on peritoneal solute transport rate in new peritoneal dialysis patients: a 1-ye ar prospective study. (20100731)Cho J.H.... Kim Y.L.2010BMP6, MUC16
3Fungal peritonitis in peritoneal dialysis: risk factors and prognosis. (19142806)Oygar D.D.... Serdengecti K.2009ALB
4Roles of neutrophil gelatinase-associated lipocalin in continuous ambulatory peritoneal dialysis-related peritonitis. (19148711)Leung J.C.... Lai K.N.2009LCN2
5Prolonged use of the tyrosine kinase inhibitor in a peritoneal dialysis patient with metastatic renal cell carcinoma: possible beneficial effects on peritoneal membrane and peritonitis rates. (19255867)Tapiawala S.N.... Simons M.2009VEGFA
6Tuberculous peritonitis in cirrhotic patients: compar ison of spontaneous bacterial peritonitis caused by Escherichia coli with tuber culous peritonitis. (19922068)Kim N.J.... Kim Y.S.2009ADA
7Peritoneal protein clearance and not peritoneal membr ane transport status predicts survival in a contemporary cohort of peritoneal d ialysis patients. (19478100)Perl J.... Davies S.J.2009ALB
8Proteomic analysis of peritoneal dialysate fluid in patients with dialysis-related peritonitis. (18791950)Lin W.T.... Wu Y.J.2008B2M
9Rosiglitazone, a peroxisome proliferator-activated re ceptor agonist, improves peritoneal alterations resulting from an encapsulated peritoneal sclerosis model. (18985998)Bozkurt D.... Duman S.2008PPARA
10Fas expression on peritoneal macrophages during continuous ambulatory peritoneal dialysis peritonitis. (18350449)Chen C.Y.... Chiang H.C.2008CD69
11Mineralocorticoid receptor blockade ameliorates peritoneal fibrosis in new rat peritonitis model. (18353870)Nishimura H.... Matsuo S.2008SERPINE1, SGK1
12Concentration of adipokines in peritoneal effluent: a new marker of acute peritonitis in peritoneal dialysis patients? (18708547)Kolonko A.... Wiecek A.2008IL6
13Procalcitonin fails to differentiate inflammatory status or predict long-term outcomes in peritoneal dialysis-associated peritonitis. (18556380)Lam M.F.... Lai K.N.2008CALCA, CRP
14Hepatocyte growth factor prevents peritoneal fibrosis in an animal model of encapsulating peritoneal sclerosis. (18264938)Matsuoka T.... Kanamaru A.2008HGF
15Inflammatory peritoneal reaction after perforated appendicitis: continuous peritoneal lavage versus non lavage. (17513191)Schwarz A.... Orth K.2007CRP, S100A8, S100A9
16Peritonitis, peritoneal inflammation and membrane permeability: a longitudinal study of dialysate and serum MCP-1 in stable patients on peritoneal dialysis. (17557268)Malik A.R.... Brown E.A.2007CCL2
17Hyperleptinaemia and chronic inflammation after peritonitis predicts poor nutritional status and mortality in patients on peritoneal dialysis. (17277343)Lam M.F.... Lai K.N.2007LSL
18Proteomic analysis of peritoneal dialysate fluid in patients with different types of peritoneal membranes. (17924681)Sritippayawan S.... Thongboonkerd V.2007IGKC
19Relationship between effluent levels of beta(2)-micro globulin and peritoneal injury markers in 7.5% icodextrin-based peritoneal dial ysis solution. (17661836)Minami S.... Higuchi M.2007MMP2, IL6
20Relationship of ENOS and RAS gene polymorphisms to initial peritoneal transport status in peritoneal dialysis patients. (16741369)Akcay A.... Ozdemir F.N.2006NOS3, ACE, AGTR1
21Peritoneal clearance of biochemical markers of bone turnover in children with end stage renal failure on peritoneal dialysis. (16848114)Bayazit A.K.... Anarat A.2006SLPI
22Interleukin-12 and -18 levels in peritoneal dialysate effluent correlate with the outcome of peritonitis in patients undergoing peritoneal dialysis: implications for the Type I/Type II T-cell immune response. (16112053)Wang H.H.... Lin C.Y.2005T
23Markers in peritoneal effluent for withdrawal from peritoneal dialysis: multicenter prospective study in Japan. (16686304)Kawanishi H.... Naito H.2005ALB
24Restoration of peritoneal integrity after withdrawal of peritoneal dialysis: characteristic features of the patients at risk of enca psulating peritoneal sclerosis. (16362159)Otsuka Y.... Kawaguchi Y.2005MUC16
25Regulation of peritoneal and systemic neutrophil-derived tumor necrosis factor-alpha release in patients with severe peritonitis: role of tumor necrosis factor-alpha converting enzyme cleavage. (15942356)Kermarrec N.... Chollet-Martin S.2005ADAM17
26The Euro-Balance Trial: the effect of a new biocompatible peritoneal dialysis fluid (balance) on the peritoneal membrane. (15200450)Williams J.D.... Passlick-Deetjen J.2004VEGFA, MUC16
27Early detection of peritonitis in continuous ambulatory peritoneal dialysis patients by cytokine measurements. (12812261)Oymak Y.... YalAsin A.S.2003IL6
28Gastrointestinal and pancreatic function in peritoneal dialysis patients: their relationship with malnutrition and peritoneal membrane abnormalities. (14520630)Aguilera A.... Selgas R.2003GAST
29Interleukin-6 differentially stimulates haptoglobin production by peritoneal and endometriotic cells in vitro: a model for endometrial-peritoneal interaction in endometriosis. (11397854)Piva M.... Sharpe-Timms K.L.2001IL6, HP
30Inflammation, peritoneal transport, and response to erythropoietin in peritoneal dialysis patients. (11510266)Pilkey R.M.... Iliescu E.A.2001TF, ALB, CRP
31Longitudinal study of peritoneal membrane function in continuous ambulatory peritoneal dialysis: relationship with peritonitis and fibrosing factors. (11216559)Wong T.Y.... Li P.K.2000MUC16
32Leptin in peritoneal dialysate from continuous ambulatory peritoneal dialysis patients. (10561138)Tsujimoto Y.... Morii H.1999LEP
33Peritoneal kinetics of cancer antigen 125 in peritoneal dialysis patients: the relationship with peritoneal outcome. (10682069)JimAcnez C.... Gonzalez-Gancedo P.1999MUC16
34Use of bolus intraperitoneal iron dextran in continuous ambulatory peritoneal dialysis or continuous cyclic peritoneal dialysis patients receiving recombinant human erythropoietin. (10682073)Mars R.L.... Hargrove P.1999TF, EPO
35Peritoneal fluid cytokine and eicosanoid levels and their relation to the incidence of peritoneal adhesion. (10376272)Chegini N.... Stone I.K.1999TGFB1, IL1B, CSF2
36Middle molecules in peritoneal equilibration test as a marker of peritoneal stress in children on continuous peritoneal dialysis. (10682119)Laux C.... Bonzel K.E.1999B2M, CST3, AMBP
37Serial cytokine changes in peritoneal effluent and plasma during peritonitis in patients on continuous ambulatory peritoneal dialysis (CAPD). (9137991)KozioA8-Montewka M.... Baranowicz I.1997IL6
38Adequacy of dialysis and nutrition in continuous peritoneal dialysis: association with clinical outcomes. Canada-USA (CANUSA) Peritoneal Dialysis Study Group. (8785388)1996ALB
39Effects of intraperitoneal cyclooxygenase inhibition on inflammatory mediators in dialysate and peritoneal membrane characteristics during peritonitis in continuous ambulatory peritoneal dialysis. (7636393)Zemel D.... Krediet R.T.1995IL6, B2M
40Analysis of inflammatory mediators and peritoneal permeability to macromolecules shortly before the onset of overt peritonitis in patients treated with CAPD. (7612733)Zemel D.... Krediet R.T.1995B2M
41Role of peritoneal loss of albumin in the hypoalbuminemia of continuous ambulatory peritoneal dialysis patients: relationship to peritoneal transport of solutes. (8569981)Kagan A.... Bar-Khayim Y.1995ALB, CD40LG, CD79A
42Dual arterial infusion chemotherapy, continuous hype rthermic peritoneal perfusion, and total parietal peritonectomy for peritoneal dissemination in gastric cancer--a case report (7944473)Fujimura T.... Sugiyama K.1994MUC16
43Relationship of TNF-alpha, interleukin-6, and prostag landins to peritoneal permeability for macromolecules during longitudinal follo w-up of peritonitis in continuous ambulatory peritoneal dialysis. (8245688)Zemel D.... Krediet R.T.1993IL6
44Peritoneal catheter loss and death in continuous ambulatory peritoneal dialysis peritonitis: correlation with clinical and biochemical parameters. (8399604)Tzamaloukas A.H.... Fox L.1993ALB, SLC17A5
45Detection of neutrophil granulocytes in peritoneal dialysis effluents by means of the Cytur-test. Danish Study Group on Peritonitis in Dialysis (DASPID). (2042020)Antonsen S.... Wang P.1991ALB
46Activity of some lysosomal enzymes in peritoneal lymphocytes from patients with terminal renal failure treated by intermittent peritoneal dialysis. (1784945)SuA8owicz W.... Kosiniak-Kamysz A.1991GSR, GUSB, NAGLU
47Release of hydrogen peroxide and expression of HLA-DR and transferrin receptors by monocytes and peritoneal macrophages from patient s undergoing continuous ambulatory peritoneal dialysis and normal controls. (2379325)McGregor S.J.... Junor B.J.1990TFRC
48Acid phosphatase, beta-glucuronidase and N-acetyl-bet a-D-glucosaminidase activity of peritoneal neutrophils in patients with termina l renal failure treated by intermittent peritoneal dialysis. (2330808)SuA8owicz W.... Slipek A.1990GUSB
49Peritonitis-related deaths in continuous ambulatory peritoneal dialysis (CAPD) patients. (2085582)Digenis G.E.... Oreopoulos D.G.1990ALB
50Bacterial peritonitis and beta-2 microglobulin (B2M) production by peritoneal macrophages (PM0) in CAPD patients. (1982784)Carozzi S.... Salit M.1990B2M

Expression for genes affiliated with Peritonitis

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1BioGPS
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Expression patterns in normal tissues for genes affiliated with Peritonitis

Pathways for genes affiliated with Peritonitis

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36QIAGEN, 20KEGG, 38Reactome, 10EMD Millipore, 41Thomson Reuters, 3Cell Signaling Technology, 37R&D Systems
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Pathways related to peritonitis according to GeneDecks:

(show top 50)    (show all 146)
idPathwayScoreTop Affiliating Genes
1Rho Family GTPases3615.3KIT, KITLG, VIM, BMP6, BMP7, LIF
2Akt Signaling3614.7PDE3B, KIT, BMP7, LIF, MST1R, CD28
3Cytokine-cytokine receptor interaction2014.5CNTF, KIT, KITLG, VEGFA, BMP7, LIF
4all-trans-Retinoic Acid Signaling in Brain3614.5BMP6, BMP7, RARA, LIF, BCL2, BAX
5Immune System3813.5NCR2, KIR2DL1, KIR2DL3, KIR3DL1, VCAM1, LGALS3
6PEDF Induced Signaling3613.5RELA, SERPINF1, BMP6, BMP7, LIF, BCL2
7STAT3 Pathway3613.3BMP6, BMP7, LIF, BCL2, BAX, JAK2
8Rheumatoid arthritis2013.1VEGFA, JUN, CD28, CD86, CD80, ITGB2
9Malaria2013.0LRP1, SELE, SELP, VCAM1, MYD88, CD36
10Phospholipase-C Pathway3612.8KIT, KITLG, BMP6, BMP7, KDR, CD79A
11RAR-Gamma-RXR-Alpha Degradation3612.5BMP7, LIF, CD80, IL11, IL15, IL16
12Glioma Invasiveness3612.4KITLG, VTN, BMP6, BMP7, CD44, ITGA3
13Actin-Based Motility by Rho Family GTPases3612.2BMP7, ITGA4, ITGA6, ITGAM, ITGAV, ITGAX
14Selected targets of C/EBPalpha1012.2SERPINC1, SCGB1A1, CETP, CD36, MMP8, APOB
15Rac1 Pathway3611.9KITLG, BMP6, BMP7, KDR, JUN, ITGA2
16Immune response_Bacterial infections in normal airways4111.9RELA, RELB, MYD88, LBP, CD14, IL1B
17Bacterial infections in CF airways4111.7RELA, RELB, MYD88, MUC1, LBP, IL1R1
18Cytokine production by Th17 cells in CF4111.7RELA, RELB, MYD88, LBP, JAK2, CD14
19DHA Signaling3611.7KIT, KITLG, SERPINF1, BMP6, BMP7, KDR
20NFAT Signaling and Lymphocyte Interactions3611.7BMP6, BMP7, BCL2, BAX, CD80, IL11
21Activation of PKA through GPCR3611.6PDE2A, PDE3B, KIT, KITLG, BMP6, BMP7
22SOCS Pathway3611.5BMP6, BMP7, BCL2, BAX, JAK2, CD80
23Pancreatic Adenocarcinoma3611.5KIT, KITLG, BRCA2, BMP6, BMP7, BIRC5
24Paxillin Interactions3611.5KIT, KITLG, VCL, KDR, BCAR1, MST1R
25ERK5 Signaling3611.4KIT, KITLG, BMP6, BMP7, KDR, FOS
26eNOS Signaling3611.3KIT, KITLG, BMP6, BMP7, BDKRB2, MST1R
27Angiogenesis311.3REN, VHL, KDR, MST1R, ITGA5, ITGA6
28p53 Mediated Apoptosis3611.2KIT, KITLG, BMP6, BMP7, KDR, BCL2
29PPAR Pathway3611.1KIT, KITLG, ITGA2, ITGA3, ITGA4, ITGA5
30Signal transduction_PTEN pathway4111.1PCNA, BCAR1, ITGA5, ITGB1, GSK3B, IGF1R
31Pancreatic cancer2011.1BRCA2
32PGC1Alpha Pathway3611.0BMP6, BMP7, BCL2, BAX, CD80, INSR
33Colorectal cancer2011.0FOS, GSK3B, MAPK8, CASP9, SMAD2, SMAD3
34Immune response MIF-mediated glucocorticoid regulation1010.9RELA, RELB, VCAM1, JUN, MMP1, FOS
35Immune response_MIF-mediated glucocorticoid regulation4110.9RELA, RELB, VCAM1, JUN, MMP1, FOS
36CDC42 Pathway3610.8KIT, KDR, MST1R, JUN, CDH1, ITGA2
37Nanog in Mammalian ESC Pluripotency3610.8KIT, KITLG, BMP6, BMP7, KDR, MST1R
38Tuberculosis2010.7RELA, VDR, MYD88, BCL2, BAX, LBP
39NFAT in Immune Response3610.5KIT, KITLG, BMP6, BMP7, KDR, MST1R
40eIF2 Pathway3610.4KIT, KITLG, BMP6, BMP7, FLT4, INS
41Development_VEGF signaling via VEGFR2 - generic cascades4110.3RELA, VEGFA, VCL, JUN, ITGAV, ITPR1
42Sertoli-Sertoli Cell Junction Dynamics3610.3VCL, CLDN4, CLDN15, CLDN3, BCAR1, CDH1
43Pathways in cancer2010.2RELA, RET, BRCA2, VEGFA, RARA, BIRC5
44Estrogen Pathway3610.1KIT, KITLG, BRCA1, BMP6, BMP7, KDR
45p70S6K Signaling369.9KIT, KITLG, BMP6, BMP7, KDR, JAK2
46GPCR Pathway369.8KIT, KITLG, BMP6, BMP7, KDR, MST1R
47TGF-beta Signaling Pathways379.8RELA, RELB, ATF1, JUN, FOS, MAPK8
48Development_EGFR signaling pathway419.8RELB, JUN, MMP2, MMP9, FOS, GSK3B
49Signal transduction PTEN pathway109.5PCNA, BCAR1, JUN, ITGA5, ITGB1, GSK3B
50Prostate cancer209.5RELA, BCL2, CDK2, INS, GSK3B, FGFR2

Compounds for genes affiliated with Peritonitis

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32Novoseek , 18HMDB, 9DrugBank, 42Tocris Bioscience, 34PharmGKB
See all sources

Compounds related to peritonitis according to GeneDecks:

(show top 50)    (show all 517)
idCompoundScoreTop Affiliating Genes
1serine32 26.2LRP1, LRPAP1, PDE3B, REG1A, RELA, RET
2creatinine32 21.5REN, SGK1, KITLG, VWF, PCNA, GC
3vegf32 21.4PIK3C2A, LRP1, REN, RET, CNTF, KIT
4estrogen32 19.9COG2, VWF, PCNA, GC, RBP4, SERPINC1
5ribonucleic acid32 16.2RET, KIT, KITLG, RBP4, SERPINB2, NAMPT
6h2o232 15.7SGK1, CNTF, KITLG, VWF, SELL, SERPINB2
7histamine32 18 16.6PDE3B, CNTF, KIT, KITLG, VWF, PCNA
8phospholipid32 15.1COG2, VWF, RBP4, LPL, VCL, BPI
9adenylate32 14.4PDE3B, SGK1, CNTF, KITLG, VWF, GC
10sialic acid32 13.9RBP4, SELL, SELPLG, SERPINF2, NAGLU, LPA
11actinomycin d32 13.4SGK1, CNTF, KIT, KITLG, SELE, SETD2
12prostacyclin32 13.4PIK3C2A, PDE2A, PDE3B, REN, VWF, VTN
13ly29400232 13.4PIK3C2A, RET, SGK1, VTN, SELE, VHL
14copper32 18 14.0RBP4, NAGLU, LPA, LIF, MT3, MT-CYB
15dbc-amp32 12.9LRP1, PDE3B, VIM, NAGLU, BMP6, LIF
16alginate32 12.6VCAN, BMP7, LIF, BGLAP, CD79A, CD36
17choline32 9 18 9 15.3PIK3C2A, RET, CNTF, VIM, LIF, BLVRB
18nmda32 42 13.3LRP1, VIM, BLVRB, BCHE, SCARB1, LEP
19captopril32 42 9 9 15.2REN, BDKRB2, B2M, CD79A, MMP2, IL1A
20thalidomide32 42 9 9 15.2VTN, SELL, VEGFA, BIRC5, KDR, B2M
21azathioprine32 34 9 9 15.2PCNA, VIM, LIF, BGLAP, CHKB, MUC2
22pmma32 12.1VTN, SELP, VCL, BMP6, B2M, CD40LG
23slex32 12.0SELE, SELL, SELP, SELPLG, VCAM1, MUC1
24ganciclovir32 9 9 13.9KITLG, VIM, BMP6, KDR, LEP, CEACAM3
25fitc32 11.9VWF, PCNA, SELL, BIRC5, LBP, CD86
26salicylic acid32 11.7VDR, XDH, CD40, MMP3, IL13, IL1RAPL2
27niacin32 9 9 13.5COG2, NAMPT, LPA, LPL, SCARB1, CETP
28mycophenolate mofetil32 9 9 13.5SELE, SELP, SERPINE1, CD79A, CD36, CD40LG
29sp 60012532 42 12.4VCAM1, CD40, MMP1, IL13, IL17A, CASP3
30hirudin32 11.3SELL, SERPINC1, SERPINF2, FGA, F10, PLAU
31phenylephrine32 9 18 9 14.3LPL, LIF, LEP, CGA, CGB5, APOB
32rosuvastatin32 34 9 9 14.3COG2, CHKB, CETP, INS, IL6, APOA1
33orlistat32 42 9 9 14.2LPL, LIPC, LEP, INS, APOB, FAS
34nitroglycerin32 9 9 13.2COG2, BLVRB, B2M, TNFRSF11B, SST, ELANE
35corticosterone32 18 12.2LIF, BGLAP, LEPR, CGB5, MPO, FOS
36raloxifene32 9 9 13.0VWF, SERPINC1, SERPINE1, VDR, BGLAP, CHKB
37carbon32 10.9VWF, VTN, PCNA, LPL, VDR, BLVRB
38hcec32 10.8VCAM1, KDR, IL6, MAPK8, MAPK1, IFNB1
39daunorubicin32 9 9 12.7RELA, KITLG, BIRC5, BCL2, BAX, XDH
40gemcitabine32 34 9 9 13.5PCNA, BRCA1, VEGFA, BNIP3, BIRC5, KDR
4115-deoxy-delta-12,14-prostaglandin j232 10.4SERPINE1, VEGFA, VCAM1, BMP6, BIRC5, JUN
42capecitabine32 34 9 9 12.8KIT, VEGFA, MTHFR, CES1, ERBB2, CYP19A1
43suramin32 9 9 11.6LRP1, LRPAP1, PCNA, VEGFA, BMP6, KDR
44rottlerin32 42 10.6VCAM1, JUN, CD36, CD40LG, ITGAM, IL6R
45ag 147832 9.6SERPINE1, MUC5AC, JUN, JAK2, CDK2, ITGA2
46pertussis32 9.6JUN, ITGA4, ITGB2, FOS, FGFR2, MAPK10
47docetaxel32 34 9 9 12.6KIT, SETD2, BRCA1, BRCA2, VEGFA, VDR
48geldanamycin32 9 9 11.6SETD2, VEGFA, VCL, BIRC5, KDR, JUN
49indole-3-carbinol32 9.5BRCA1, BRCA2, BIRC5, BCL2, BAX, CDK2
50etoposide32 42 9 9 12.4PCNA, SELE, SETD2, RARA, BIRC5, BCL2

GO Terms for genes affiliated with Peritonitis

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Sources:
12Gene Ontology
See all sources

Cellular components related to peritonitis according to GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00557624.7ST3GAL4, AGER, HBEGF, ELANE, C9, EGF
2extracellular spaceGO:00561523.7AFP, AFM, EPO, HGF, TNFRSF1A, F2
3plasma membraneGO:00588623.0BCAR1, SELE, KIR3DL1, KITLG, KIR2DL3, KIR2DL1
4integral to plasma membraneGO:00588717.3HRH2, IL15, FCAR, MET, FGFR2, INSR
5cell surfaceGO:00998613.5THBD, TIMP2, TLR2, HBEGF, ELANE, ABCB1
6cytosolGO:00582913.3GPT, GSR, GSK3B, INSR, ARG1, ARAP3
7external side of plasma membraneGO:00989712.6IFNG, ITGA5, ITGA4, ITGA2, CD9, CD44
8extracellular matrixGO:03101212.3SLPI, SOD3, SOD1, PRTN3, DCN, TGFB3
9platelet alpha granule lumenGO:03109311.3HGF, SERPINF2, VWF, SERPINE1, VEGFA, LEFTY2

Biological processes related to peritonitis according to GeneDecks:

(show all 50)
idNameGO IDScoreTop Affiliating Genes
1inflammatory responseGO:00695415.8RELA, KIT, SELE, SELP, MYD88, BMP6
2immune responseGO:00695515.7KIR2DL1, KIR2DL3, KIR3DL1, VTN, BPI, BMP6
3signal transductionGO:00716515.3NCR1, NCR2, RET, CNTF, KIT, KITLG
4positive regulation of cell proliferationGO:00828414.6REG1A, CNTF, KIT, SFRP2, NAMPT, VEGFA
5cell adhesionGO:00715514.6KITLG, VWF, VTN, SELL, SELP, SELPLG
6small molecule metabolic processGO:04428114.3PIK3C2A, GC, NAGLU, NAMPT, LPA, LPL
7cell-cell signalingGO:00726714.2SFRP2, NAMPT, S100A9, CGA, CGB, CEACAM6
8response to hypoxiaGO:00166613.6VEGFA, VCAM1, BNIP3, CLDN3, BCL2, LEP
9negative regulation of cell proliferationGO:00828513.5SFRP2, VHL, VDR, LIF, BDKRB2, JUN
10leukocyte migrationGO:05090013.2SELL, SELP, SELPLG, CD34, ITGA3, ITGA4
11negative regulation of apoptotic processGO:04306613.0RELA, SERPINE1, VEGFA, BDKRB2, KDR, BCL2
12apoptotic processGO:00691512.9SGK1, VIM, BRCA1, BNIP3, BIRC5, BCL2
13positive regulation of transcription from RNA polymerase II promoterGO:04594412.9RELA, SFRP2, SERPINF2, SERPINE1, BRCA1, VEGFA
14G-protein coupled receptor signaling pathwayGO:00718612.8CMKLR1, BDKRB2, BCAR1, JAK2, ITPR3, INS
15blood coagulationGO:00759612.8PDE2A, PDE3B, VWF, SELL, SELP, SELPLG
16anti-apoptosisGO:00691612.6RELA, SERPINB2, VHL, BNIP3, MYD88, BIRC5
17response to drugGO:04249312.5REN, SFRP2, LPL, BGLAP, BDKRB2, BCHE
18agingGO:00756812.5SERPINF1, VDR, VCAM1, JUN, IL15, IL1B
19cell surface receptor signaling pathwayGO:00716612.5MYD88, BDKRB2, LEPR, BAG1, CD28, CD36
20innate immune responseGO:04508712.4RELA, MYD88, BCL2, LGALS3, LCN2, LBP
21chemotaxisGO:00693512.3CMKLR1, S100A8, S100A9, FGF2, IL4, ENPP2
22positive regulation of cell migrationGO:03033512.2RET, VEGFA, KDR, BCAR1, CGA, JAK2
23positive regulation of transcription, DNA-dependentGO:04589312.2RELA, RET, BRCA1, BRCA2, VHL, BMP7
24virus-host interactionGO:01904812.2RELA, VIM, VCAM1, BNIP3, KDR, SCARB1
25response to glucocorticoid stimulusGO:05138412.2SERPINF1, SERPINE1, BGLAP, BCHE, LCAT, INSR
26positive regulation of angiogenesisGO:04576612.1SFRP2, SERPINE1, VEGFA, KDR, MTDH, CD34
27response to lipopolysaccharideGO:03249612.0SELE, SELP, LBP, S100A8, S100A9, JUN
28platelet degranulationGO:00257612.0VWF, SELP, SERPINF2, SERPINE1, VEGFA, VCL
29regulation of immune responseGO:05077612.0KIR2DL1, KIR2DL3, KIR3DL1, SELL, VCAM1, B2M
30positive regulation of peptidyl-tyrosine phosphorylationGO:05073111.9KITLG, VTN, VEGFA, LIF, JAK2, CD36
31positive regulation of inflammatory responseGO:05072911.9PDE2A, SERPINE1, JAK2, IL15, IL18, IL2
32female pregnancyGO:00756511.9GC, CLDN4, PAPPA, BCL2, SCGB1A1, LEP
33positive regulation of protein phosphorylationGO:00193411.8VEGFA, MT3, CD40, ITLN1, FLT4, INSR
34positive regulation of apoptotic processGO:04306511.7SFRP2, BAX, JAK2, ITGA6, ITGB1, MMP9
35positive regulation of ERK1 and ERK2 cascadeGO:07037411.6SERPINF2, KDR, MT3, CD44, FLT4, MIF
36positive regulation of protein kinase B signaling cascadeGO:05189711.5MTDH, MST1R, INS, INSR, ILK, ANGPT1
37positive regulation of MAPK cascadeGO:04341011.5CNTF, KIT, LIF, KDR, LEP, CD36
38response to estradiol stimulusGO:03235511.4GC, BRCA2, VDR, RARA, MMP9, INSR
39heart developmentGO:00750711.4PCNA, RBP4, VCAM1, VCAN, ITGA4, MB
40lipopolysaccharide-mediated signaling pathwayGO:03166311.3MYD88, SCARB1, LBP, MTDH, IL18, IL1B
41platelet activationGO:03016811.3VWF, SELP, SERPINF2, SERPINE1, VEGFA, VCL
42cellular response to mechanical stimulusGO:07126011.3PDE2A, BNIP3, MYD88, CD40, ITGB1, IL13
43response to mechanical stimulusGO:00961211.2BGLAP, JUN, MMP9, MGP, ANGPT2, CCL2
44response to ethanolGO:04547111.2RBP4, BGLAP, BCL2, S100A8, S100A9, MMP9
45angiogenesisGO:00152511.1PDE3B, SETD2, SERPINE1, VEGFA, KDR, JUN
46positive regulation of smooth muscle cell proliferationGO:04866111.1SERPINF2, MYD88, JUN, FLT1, IL13, IL6
47response to woundingGO:00961111.0VWF, FN1, MET, CCR1, ID3, F2
48positive regulation of phosphatidylinositol 3-kinase cascadeGO:01406810.9CNTF, KIT, SELP, KDR, JAK2, FLT1
49positive regulation of nitric oxide biosynthetic processGO:04542910.8JAK2, INS, INSR, IL1B, IFNG, ICAM1
50activation of MAPK activityGO:0001879.8KIT, INSR, FGF2, MET, IL1B, MAPK3

Molecular functions related to peritonitis according to GeneDecks:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:00551522.9ADM, ADA, ADAM17, ADIPOQ, HGF, EPCAM
2receptor bindingGO:00510214.5SERPINE1, ANGPT2, ANXA1, CCL2, F7, F2
3cytokine activityGO:00512514.0LEFTY2, CD40LG, FLT3LG, MIF, INHA, INHBA
4growth factor activityGO:00808312.7REG1A, CNTF, KITLG, VEGFA, BMP6, BMP7
5heparin bindingGO:00820112.3LPL, PRG2, CXCL6, SOD3, PGF, HBEGF
6enzyme bindingGO:01989911.8NFKBIA, NOD2, PLAUR, PPARG, CTNNB1, PTGS2
7protein homodimerization activityGO:04280311.7BIRC5, BCL2, SCARB1, BAX, S100A1, S100A6
8protease bindingGO:00202011.2SERPINF2, SERPINE1, BRCA2, BDKRB2, BCL2, CD28
9hormone activityGO:00517911.0LEP, CGA, CGB, INHA, INHBA, INS

Sources for Peritonitis

about this section
2CDC
11FMA
18HMDB
19ICD9CM
20KEGG
24MeSH
25MGI
27NCIt
28NDF-RT
31NINDS
32Novoseek
33OMIM
35PubMed
36QIAGEN
43UMLS
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