MCID: PRX034
MIFTS: 40

Peroxisome Disorders malady

Category: Rare diseases

Aliases & Classifications for Peroxisome Disorders

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Aliases & Descriptions for Peroxisome Disorders:

Name: Peroxisome Disorders 47
Peroxisomal Disorders 49 67
Disorder of Peroxisomal Function 47
 
Peroxisomal Disease 47
Peroxisome Diseases 47
Peroxisomal Defects 47

Classifications:



Summaries for Peroxisome Disorders

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MalaCards based summary: Peroxisome Disorders, also known as peroxisomal disorders, is related to peroxisomal disease and peroxisome biogenesis disorder 9b. An important gene associated with Peroxisome Disorders is GNPAT (Glyceronephosphate O-Acyltransferase), and among its related pathways are alpha-linolenic (omega3) and linoleic (omega6) acid metabolism and Glyoxylate and dicarboxylate metabolism. Affiliated tissues include kidney, skeletal muscle and heart, and related mouse phenotypes are reproductive system and endocrine/exocrine gland.

Related Diseases for Peroxisome Disorders

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Diseases related to Peroxisome Disorders via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 51)
idRelated DiseaseScoreTop Affiliating Genes
1peroxisomal disease31.9PEX1, PEX2, PEX5
2peroxisome biogenesis disorder 9b30.7HADHB, HSD17B4, PEX5, PEX7
3refsum disease11.0
4adrenoleukodystrophy11.0
5peroxisome biogenesis disorder 1a10.9
6peroxisome biogenesis disorder 14b10.8
7alpha-methylacyl-coa racemase deficiency10.8
8d-bifunctional protein deficiency10.8
9peroxisomal fatty acyl-coa reductase 1 disorder10.8
10peroxisome biogenesis disorder 6a10.6
11peroxisome biogenesis disorder 13a10.6
12peroxisome biogenesis disorder 12a10.6
13chondrodysplasia punctata, rhizomelic, type 210.6
14peroxisome biogenesis disorder 11a10.6
15chondrodysplasia punctata, rhizomelic, type 310.6
16peroxisome biogenesis disorder 4a10.6
17chondrodysplasia punctata, rhizomelic, type 110.6
18peroxisome biogenesis disorder 10a10.6
19peroxisome biogenesis disorder 5a10.6
20acatalasemia10.6
21peroxisome biogenesis disorder 8a,10.6
22peroxisome biogenesis disorder 2a10.6
23peroxisome biogenesis disorder 3a10.6
24peroxisome biogenesis disorder 7a10.6
25wandering spleen10.1ABCD1, HSD17B4, PEX5
26metaphyseal dysplasia, braun-tinschert type10.0GNPAT, PEX5, PEX7
27adult neuronal ceroid lipofuscinosis10.0ABCD1, SLC25A17
28polycystic kidney disease, autosomal dominant9.9PEX1, PEX2, PEX5
29perrault syndrome 19.9HADHB, HSD17B4
30rhizomelic chondrodysplasia punctata9.9
31lacrimal gland adenocarcinoma9.9AGXT, PEX5
32growth hormone deficiency, isolated, type ii9.8PEX1, PEX5, PEX7, TRIM37
33cholinergic urticaria9.8ABCD1, PEX5, SLC25A17
34pepck 2 deficiency9.7PEX1, PEX2, PEX5, PEX7
35mulibrey nanism9.7
36neonatal adrenoleukodystrophy9.7
37larynx cancer9.6AGPS, GNPAT, PEX5, PEX7, PHYH
38child syndrome9.5
39cataract9.5
40hepatitis9.5
41skin disease9.5
42epilepsy9.5
43lactic acidosis9.5
44peroxisomal biogenesis disorders9.5
45intellectual disability9.5
46mental retardation, autosomal recessive 449.4AGXT, CAT, HSD17B4, PEX5
47ritter's disease9.4ABCD1, GNPAT, HADHB, HSD17B4, PEX2, PEX5
48granulosa cell tumor of the ovary9.1CAT, PEX1, PEX11B, PEX2, PEX5, PEX7
49deafness, dystonia, and cerebral hypomyelination9.1ABCD1, CAT, HSD17B4, PEX1, PEX5, SLC25A17
50immunodeficiency 41 with lymphoproliferation and autoimmunity8.6CAT, GNPAT, HADHB, PEX1, PEX2, PEX5

Graphical network of the top 20 diseases related to Peroxisome Disorders:



Diseases related to peroxisome disorders

Symptoms for Peroxisome Disorders

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Drugs & Therapeutics for Peroxisome Disorders

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Drugs for Peroxisome Disorders (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 200)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Pioglitazoneapproved, investigationalPhase 4, Phase 3, Phase 2, Phase 1435111025-46-84829
Synonyms:
(+-)-5-((4-(2-(5-Ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione
(+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione
(+/-)-5-[[4-[2-(5-Ethyl-2-pyridinyl)-ethoxy]phenyl]methyl]-2,4-thiazolidinedione
(+/-)-5-[p-[2-(ethyl-2-pyridyl)ethoxy]benzyl]-2,4-thiazolidinedione
105355-27-9
111025-46-8
198077-89-3
2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]- (9CI)
5-((4-(2-(5-Ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione
5-(4-(2-(5-ethyl-2-pyridyl)ethoxy)benzyl)-2,4-thiazolidinedione
5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]thiazolidine-2,4-dione
5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione
5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]thiazolidine-2,4-dione
5-[[4-[2-[(5-ethyl-2-pyridyl)]ethoxy]phenyl]methyl]thiazolidine- 2,4-dione
5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione
AB1004597
AC-1021
AC1L1J1Q
AD 4833
AD-4833
Actos
Actos (TN)
Actost
BRD-A48430263-003-02-4
BSPBio_002723
C07675
C19H20N2O3S
CHEBI:8228
CHEMBL595
CID4829
D08378
DB01132
Duetact
Glustin
HMS2089H14
HS-0047
 
HSDB 7322
I06-0089
KBio2_002103
KBio2_004671
KBio2_007239
KBio3_001943
KBioGR_001619
KBioSS_002103
LS-151327
MolPort-002-508-211
NCGC00163128-01
NCGC00163128-02
Pioglitazona
Pioglitazona [INN-Spanish]
Pioglitazone
Pioglitazone HCl
Pioglitazone Hydrochloride
Pioglitazone [BAN:INN]
Pioglitazone [Ban:Inn]
Pioglitazone [INN:BAN]
Pioglitazonum
Pioglitazonum [INN-Latin]
SPBio_001897
Spectrum2_001679
Spectrum3_001002
Spectrum4_001130
Spectrum5_001480
Spectrum5_002067
Spectrum_001623
U 72107
U 72107A
U-72107
U72,107A
UNII-X4OV71U42S
Zactos
nchembio790-comp10
pioglitazone (INN)
pioglitazone HCl
2
Aspirinapproved, vet_approvedPhase 4111250-78-22244
Synonyms:
11126-35-5
11126-37-7
1oxr
2-(ACETYLOXY)benzoic acid
2-(Acetyloxy)benzoate
2-(Acetyloxy)benzoic acid
2-Acetoxybenzenecarboxylic acid
2-Acetoxybenzoate
2-Acetoxybenzoic acid
2-Carboxyphenyl acetate
2349-94-2
26914-13-6
50-78-2
8-hour Bayer
98201-60-6
A 5376
A.S.A
A.S.A.
A.S.A. Empirin
A.S.A. empirin
A2093_SIGMA
A3160_SIGMA
A5376_SIGMA
A6810_SIGMA
AB1003266
AC 5230
AC1L1D8U
AC1Q1LA0
ACETYLSALICYLIC ACID
AI3-02956
AIN
AKOS000118884
ASA
Acenterine
Acesal
Acetal
Acetard
Aceticyl
Acetilsalicilico
Acetilum acidulatum
Acetisal
Acetol
Acetonyl
Acetophen
Acetosal
Acetosalic acid
Acetosalin
Acetoxybenzoic acid
Acetylin
Acetylsal
Acetylsalicylate
Acetylsalicylic acid
Acetylsalicylsaeure
Acetylsalicylsaure
Acetylsalycilic acid
Acetyonyl
Acetysal
Acetysalicylic acid
Acide 2-(acetyloxy)benzoique
Acide acetylsalicylique
Acide acétylsalicylique
Acido O-acetil-benzoico
Acido acetilsalicilico
Acidum acetylsalicylicum
Acimetten
Acisal
Acylpyrin
Adiro
Aloxiprimum
Asacard
Asagran
Asatard
Ascoden-30
Aspalon
Aspec
Aspergum
Aspir-Mox
Aspirdrops
Aspirin
Aspirin (JP15/USP)
Aspirin [BAN:JAN]
Aspirina 03
Aspirine
Asprin
Aspro
Aspro Clear
Asteric
Azetylsalizylsaeure
Azetylsalizylsäure
BIDD:GT0118
BRN 0779271
Bay-e-4465
Bayer
Bayer Aspirin 8 Hour
Bayer Buffered
Bayer Extra Strength Aspirin For Migraine Pain
Bayer Plus
Benaspir
Bi-prin
Bialpirina
Bialpirinia
Bufferin
C01405
CCRIS 3243
CHEBI:15365
CHEMBL25
CID2244
Caprin
Cardioaspirin
Cardioaspirina
Cemirit
Claradin
Clariprin
Colfarit
Contrheuma retard
Coricidin
Crystar
D00109
D001241
DB00945
Decaten
Delgesic
Dispril
DivK1c_000555
Dolean pH 8
Duramax
ECM
EINECS 200-064-1
EU-0100038
Easprin
Easprin (TN)
Ecolen
Ecotrin
Empirin
Empirin with Codeine
Endosprin
Endydol
 
Entericin
Enterophen
Enterosarein
Enterosarine
Entrophen
Extren
Globentyl
Globoid
HMS1920E13
HMS2090G03
HMS2091K13
HMS501L17
HSDB 652
Helicon
I14-7505
IDI1_000555
Idragin
Istopirin
KBio1_000555
KBio2_001725
KBio2_002271
KBio2_004293
KBio2_004839
KBio2_006861
KBio2_007407
KBio3_002149
KBio3_002751
KBioGR_000398
KBioGR_002271
KBioSS_001725
KBioSS_002272
Kapsazal
Kyselina 2-acetoxybenzoova
Kyselina acetylsalicylova
LS-143
Levius
Lopac-A-5376
Lopac0_000038
MLS001055329
MLS001066332
MLS001336045
MLS001336046
Magnecyl
Measurin
Medisyl
Micristin
MolPort-000-871-622
NCGC00015067-01
NCGC00015067-04
NCGC00015067-09
NCGC00090977-01
NCGC00090977-02
NCGC00090977-03
NCGC00090977-04
NCGC00090977-05
NCGC00090977-06
NCGC00090977-07
NCI60_002222
NINDS_000555
NSC 27223
NSC27223
NSC406186
Neuronika
Novid
Nu-seals
Nu-seals aspirin
O-(Acetyloxy)benzoate
O-(Acetyloxy)benzoic acid
O-Acetoxybenzoate
O-Acetoxybenzoic acid
O-Acetylsalicylic acid
O-Carboxyphenyl acetate
O-accetylsalicylic acid
O-acetylsalicylic acid
PL-2200
Persistin
Pharmacin
Pirseal
Polopirin
Polopiryna
Premaspin
R16CO5Y76E [UNII]
Rheumin tabletten
Rheumintabletten
Rhodine
Rhonal
Ronal
S-211
SMR000059138
SP 189
SPBio_001838
SPECTRUM1500130
ST075414
Salacetin
Salcetogen
Saletin
Salicylic acid acetate
Salicylic acid, acetate
Salospir
Solfrin
Solprin
Solprin acid
Solpyron
Solupsan
Spectrum2_001899
Spectrum3_001295
Spectrum4_000099
Spectrum5_000740
Spectrum_001245
Spira-Dine
St. Joseph
St. Joseph Aspirin for Adults
Supac
Tasprin
Temperal
Toldex
Triaminicin
Triple-sal
UNII R16CO5Y76E
UNII-R16CO5Y76E
UNII=R16CO5Y76E
UNM-0000306102
Vanquish
WLN: QVR BOV1
XAXA
Xaxa
Yasta
ZORprin
aspirin
cMAP_000006
component of Midol
component of Synirin
nchem.859-comp6
o-Acetoxybenzoic acid
o-Carboxyphenyl acetate
o-acetoxybenzoic acid
o-carboxyphenyl acetate
ácido acetilsalicílico
3
BisoprololapprovedPhase 46266722-44-92405
Synonyms:
(+-)-1-((alpha-(2-Isopropoxyethoxy)-P-tolyl)oxy)-3-(isopropylamino)-2-propanol
(+-)-1-((alpha-(2-Isopropoxyethoxy)-p-tolyl)oxy)-3-(isopropylamino)-2-propanol
(RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol
(RS)-1-(4-(2-isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol
1-(propan-2-ylamino)-3-[4-(2-propan-2-yloxyethoxymethyl)phenoxy]propan-2-ol
1-[(1-methylethyl)amino]-3-({4-[({2-[(1-methylethyl)oxy]ethyl}oxy)methyl]phenyl}oxy)propan-2-ol
1-{4-[(2-isopropoxyethoxy)methyl]phenoxy}-3-(isopropylamino)propan-2-ol
66722-44-9
AB00514681
AC-18540
AC1L1DLQ
AKOS005110983
ARONIS24082
BISOPROLOL
BPBio1_000373
BSPBio_000339
Bisocor
Bisoprolol
Bisoprolol (USAN/INN)
Bisoprolol Fumarate
Bisoprolol Hemifumarate
Bisoprolol [USAN:BAN:INN]
Bisoprolol fumerate
Bisoprolol hemifumarate
Bisoprololum
Bisoprololum [Latin]
C06852
C18H31NO4
CHEBI:3127
CHEMBL645
CID2405
 
CL-297939
Cardicor
Concor
Condyline
Condylox
D02342
DB00612
Detensiel
EMD-33-512
EMD-33512
Emconcor
Emcor
Euradal
I01-7040
Isoten
L000133
LS-122509
MolPort-005-937-320
Monocor
NCGC00024868-02
NCGC00024868-03
NCGC00024868-04
NCGC00024868-05
Prestwick0_000330
Prestwick1_000330
Prestwick2_000330
Prestwick3_000330
SBB065120
SPBio_002260
Soloc
Soprol
UNII-Y41JS2NL6U
Zebeta
4
Isosorbide DinitrateapprovedPhase 45887-33-26883
Synonyms:
1,4:3, 6-Dianhydro-D-glucitol dinitrate
1,4:3,6-Dianhydro-D-glucitol dinitrate
1,4:3,6-Dianhydrosorbitol 2, 5-dinitrate
1,4:3,6-Dianhydrosorbitol 2,5-dinitrate
1,4:3,6-dianhydro-2,5-di-O-nitro-D-glucitol
54650-95-2
59812_ALDRICH
59812_FLUKA
6659-58-1
87-33-2
AB00513900
AC-12153
AC1L1NIG
Angidil
Astridine
BPBio1_001021
BSPBio_000927
BSPBio_002080
BiDil
C07456
C6H8N2O8
CCRIS 1910
CHEBI:6061
CID6883
Cardio 10
Cardis
Cardonit 40
Carvanil
Carvasin
Cedocard
Cedocard Retard
Cedocard retard
Claodical
Cornilat
Coronex
Corosorbide
Corovliss
D-Glucitol, 1,4:3,6-dianhydro-, 2,5-dinitrate
D-Glucitol, 1,4:3,6-dianhydro-, dinitrate
D-Isosorbide dinitrate
D-Isosorbide dinitrate-Lactose mixture
D00516
D007548
DB00883
Dianhydrosorbitol 2,5-dinitrate
Difutrat
Dignionitrat
Dilatrate
Dilatrate SR
Dilatrate-SR
Dilatrate-sr (TN)
Diniket
Dinitrate d'isosorbide
Dinitrate d'isosorbide [INN-French]
Dinitrate, Isosorbide
Dinitrato de isosorbida
Dinitrato de isosorbida [INN-Spanish]
Dinitroisosorbide
Dinitrosorbide
Disorlon
DivK1c_000436
EINECS 201-740-9
Emoper
EureCor
Flindix
Frandol
Glucitol, 1,4:3, 6-dianhydro-, dinitrate,
HMS1570O09
HMS1920H15
HMS2091P05
HMS501F18
HSDB 3417
Harrical
IBD 20
IDI1_000436
ISD
ISDN
ISOSORBIDE DINITRATE
Ismotic
Iso Bid
Iso-Bid
Iso-Mack
Iso-Puren
IsoBid
Isochron
Isodinit
Isoket
Isoket Retard 120
Isoket Retard-120
Isoket Retard120
 
Isoket retard 40
Isomak R
Isorbid
Isordil
Isordil (TN)
Isordil Tembids
Isosorbide 2,5-dinitrate
Isosorbide dinitrate
Isosorbide dinitrate (JP15/USP/INN)
Isosorbide dinitrate [USAN:INN:BAN:JAN]
Isosorbide dinitrate mixture with not <60% lactose, mannose, starch or calcium hydrogen phosphate [UN2907] [Flammable solid]
Isosorbide dinitrate mixture with not <60% lactose, mannose, starch or calcium hydrogen phosphate [UN2907] [Flammable solid]
Isosorbide dinitrato
Isosorbide dinitrato [DCIT]
Isosorbidi dinitras
Isosorbidi dinitras [INN-Latin]
Isosorbidi nitras
Isostat
Isotrate
KBio1_000436
KBio2_000643
KBio2_003211
KBio2_005779
KBio3_001580
KBioGR_000429
KBioSS_000643
Korodil
LS-71376
Langoran
Laserdil
Lomilan
MLS001333561
MLS001333562
Maycor
MolPort-003-666-213
Myorexon
NCGC00178830-01
NCGC00178830-02
NINDS_000436
NSC 80038
NSC80038
Nitrosorbid
Nitrosorbide
Nitrosorbon
Nosim
Prestwick0_000714
Prestwick1_000714
Prestwick2_000714
Prestwick3_000714
Prestwick_81
Resoidan
Rifloc Retard
Rigedal
SDM No. 40
SDM No. 50
SMR000857256
SPBio_001058
SPBio_002848
SPECTRUM1500358
SST-101
Sorate-10
Sorate-5
Sorbangil
Sorbide
Sorbide T.D.
Sorbide nitrate
Sorbide, dinitrate
Sorbidi nitras
Sorbidilat
Sorbidinitrate
Sorbidnitrate
Sorbislo
Sorbitrate
Sorbonit
Sorquad
Sorquat
Spectrum2_001069
Spectrum3_000600
Spectrum4_000025
Spectrum5_001057
Spectrum_000163
TYB 3215
Tinidil
Titradose
UN2907
UNII-IA7306519N
Vascardin
Vasodilat
Vasorbate
Xanyl
ZINC18089317
[(3S,3aS,6R,6aS)-3-nitrooxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] nitrate
5
Telmisartanapproved, investigationalPhase 4, Phase 2264144701-48-465999
Synonyms:
144701-48-4
2-[4-[[4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propylbenzimidazol-1-yl]methyl]phenyl]benzoic acid
4'-((1,4'-Dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid
4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid
4'-((4-Methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic acid
4'-((4-mehtyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimmidazolyl)methyl)-2-biphenylcarboxylic acid
4'-[(1,4'-Dimethyl-2'propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic acid
4'-[(1,4'-dimethyl-2'propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic acid
4'-[(1,7'-Dimethyl-2'-propyl-1H,3'h-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid
4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimidazol-3'-yl)methyl][1,1'-biphenyl]-2-carboxylic acid
4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid
AC-2013
AC1L24EB
AC1Q5U7O
Abbott brand of telmisartan
BAY-68-9291
BAY68-9291
BIBR 277
BIBR 277SE
BIBR-277
BIBR-277-SE
BIBR-277SE
BIDD:GT0365
BRD-K73999723-001-02-2
BSPBio_002738
Bay 68-9291
Bio-0103
Boehringer Ingelheim brand of telmisartan
C07710
C084178
C33H30N4O2
CHEBI:9434
CHEMBL1017
CID65999
CPD000466326
D00627
DB00966
Glaxo Wellcome brand of telmisartan
GlaxoSmithKline brand of telmisartan
 
HMS1922P07
HMS2051P16
HMS2090P17
HMS2093M22
HSDB 7590
I06-0281
KBio3_001958
KBioGR_001842
Kinzal
Kinzalmono
L001035
LS-44263
MLS000759432
MLS001076687
Micardis
Micardis (TN)
Micardis HCT
Micardis, Targit, Temax, BIBR277, Telmisartan
MolPort-003-666-621
NCGC00095150-01
NCGC00095150-02
NCGC00095150-03
Pritor
S1738_Selleck
SAM001246602
SMR000466326
SPBio_002131
SPECTRUM1505261
STK624049
Spectrum2_001976
Spectrum3_001089
Spectrum4_001261
Spectrum5_001053
TL8000991
Telmisartan
Telmisartan (JAN/USAN/INN)
Telmisartan [USAN:INN]
UNII-U5SYW473RQ
YM-086
telmisartan
6
Nitric OxideapprovedPhase 459910102-43-9145068
Synonyms:
(.)NO
(NO)(.)
10102-43-9
14332-28-6
295566_ALDRICH
51005-20-0
51005-21-1
53851-19-7
90452-29-2
AC1L1ADQ
AC1L3QHF
AC1Q6QZ0
AR-1K7463
Bioxyde d'azote
Bioxyde d'azote [French]
C00533
CCRIS 4319
CHEMBL1200689
CHEMBL1234765
CID145068
CID945
D00074
D009569
DB00435
EDRF
EINECS 233-271-0
Endogenous Nitrate Vasodilator
Endothelium-Derived Nitric Oxide
HNO
HSDB 1246
INOmax
INOmax (TN)
LS-192158
LS-7547
MolPort-003-929-452
Mononitrogen monoxide
Monoxide, Mononitrogen
Monoxide, Nitrogen
Monoxido de nitrogeno
Monoxyde d'azote
NITRIC-OXIDE
NO
NO(.)
Nitrate Vasodilator, Endogenous
Nitric Oxide, Endothelium Derived
 
Nitric Oxide, Endothelium-Derived
Nitric oxide
Nitric oxide (JAN)
Nitric oxide 10% by volume or more
Nitric oxide trimer
Nitric oxide, compressed [UN1660] [Poison gas]
Nitric oxide, compressed [UN1660] [Poison gas]
Nitrogen monoxide
Nitrogen oxide
Nitrogen oxide (NO)
Nitrogen protoxide
Nitrosyl
Nitrosyl hydride
Nitrosyl hydride ((NO)H)
Nitrosyl radical
Nitroxide radical
Nitroxyl
OHM 11771
Oxide, Nitric
Oxido de nitrogeno(ii)
Oxido nitrico
Oxyde azotique
Oxyde nitrique
Oxyde nitrique [French]
RCRA waste no. P076
Stickmonoxyd
Stickmonoxyd [German]
Stickstoff(II)-oxid
Stickstoff(ii)-oxid
Stickstoffmonoxid
UN 1660
UN1660
UNII-31C4KY9ESH
Vasodilator, Endogenous Nitrate
[NO]
endothelium-derived relaxing factor
monoxido de nitrogeno
monoxyde d'azote
nitric oxide
nitrogen monooxide
nitrogen monoxide
nitrosyl
oxido de nitrogeno(II)
oxido nitrico
oxidonitrogen(.)
oxoazanyl
oxyde azotique
7
Valsartanapproved, investigationalPhase 4291137862-53-460846
Synonyms:
(2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid
(S)-N-Valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine
(S)-N-valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine
(s)-2-(n-((2'-(1h-tetrazol-5-yl)biphenyl-4-yl)methyl)pentanamido)-3-methylbutanoic acid
137862-53-4
AC-4543
AC1L1U1M
AC1Q5QIK
Ambap137862-53-4
Aventis brand of valsartan
BIDD:GT0345
BRD-K45158365-001-02-3
BSPBio_003501
Bio-0796
C081489
C24H29N5O3
CEPA brand of valsartan
CGP 48933
CGP-48933
CHEBI:9927
CHEMBL1069
CID60846
CPD000466318
D00400
DB00177
Diovan
Diovan (TN)
Diovan, Valsartan
Esteve brand of valsartan
HMS1922L21
HMS2051L12
HMS2093K22
HSDB 7519
KBio2_002287
KBio2_004855
KBio2_007423
KBio3_003006
KBioGR_001078
KBioSS_002289
 
Kalpress
L-Valine, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- (9CI)
LS-161334
Lacer brand of valsartan
MLS000759423
MLS001424088
Miten
MolPort-002-507-854
MolPort-003-666-608
N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine
N-(P-(O-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine
N-(p-(o-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine
N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-L-valine
N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine
N-valeryl-N-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)valine
Nisis
Nisis||
Novartis brand of valsartan
Provas
S1894_Selleck
SAM001246581
SMR000466318
SPBio_001260
SPECTRUM1505209
Sanol brand of valsartan
Schwarz brand of valsartan
Spectrum2_001120
Spectrum3_001831
Spectrum4_000749
Spectrum5_001582
Spectrum_001796
TL8000869
Tareg
UNII-80M03YXJ7I
Vals
Valsarran
Valsartan (JAN/USAN/INN)
Valsartan [USAN:INN]
valsartan
walsartan
|Tareg
8
MetforminapprovedPhase 4, Phase 3, Phase 21746657-24-914219, 4091
Synonyms:
1,1-Dimethyl biguanide
1,1-Dimethylbiguanide
3-(diaminomethylidene)-1,1-dimethylguanidine
657-24-9
AC1L1HE4
AKOS000121065
Apo-Metformin
BIDD:GT0697
BPBio1_000009
BRD-K79602928-003-04-1
BSPBio_000007
BSPBio_002314
C07151
C4H11N5
CAS-1115-70-4
CCRIS 9321
CHEBI:6801
CHEMBL1431
CID4091
D04966
DB00331
DMGG
Diabetosan
Diabex
Dimethylbiguanid
Dimethylbiguanide
Dimethylbiguanidine
Dimethyldiguanide
Dimethylguanylguanidine
EINECS 211-517-8
Fluamine
Flumamine
Fortamet
Gen-Metformin
Glifage
Gliguanid
Glucophage
Glucophage XR
Glumetza
Glycon
HMS2089D19
HSCI1_000295
Haurymelin
Haurymellin
Islotin
KBio2_002310
KBio2_004878
KBio2_007446
KBio3_002790
KBioGR_002310
 
KBioSS_002312
LA-6023
LS-43899
Melbin
Metformin
Metformin (USAN/INN)
Metformin HCL
Metformin [USAN:INN:BAN]
Metformina
Metformina [DCIT]
Metformina [Spanish]
Metformine
Metformine [INN-French]
Metformine pamoate
Metforminum
Metforminum [INN-Latin]
Metiguanide
MolPort-002-929-560
MolPort-004-288-389
MolPort-005-767-418
Mylan-Metformin
N,N-Dimethylbiguanide
N,N-Dimethyldiguanide
N,N-Dimethylimidodicarbonimidic diamide
N,N-dimethylimidodicarbonimidic diamide
N1,N1-Dimethylbiguanide
NCGC00016564-01
NCGC00016564-02
NCGC00016564-03
NNDG
Novo-Metformin
Nu-Metformin
PMS-Metformin
Prestwick0_000004
Prestwick1_000004
Prestwick2_000004
Prestwick3_000004
Ran-Metformin
Ratio-Metformin
Riomet
S2483_Selleck
SPBio_001928
STK011633
Sandoz Metformin
Siofor
T5895664
Teva-Metformin
UNII-9100L32L2N
ZINC12859773
cMAP_000016
metformin
metformin hydrochloride
9
FenofibrateapprovedPhase 4, Phase 216949562-28-93339
Synonyms:
2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester
49562-28-9
AB00052196
AC-4227
AC1L1FPK
AKOS005107777
AZU, Fenofibrat
AbZ Brand of Procetofen
Abbott Brand of Procetofen
Aliud Brand of Procetofen
Ankebin
Antara
Antara (TN)
Antara (micronized)
Antara Micronized Procetofen
Anto Brand of Procetofen
Apo Feno Micro
Apo Fenofibrate
Apo-Feno-Micro
Apo-Fenofibrate
Apotex Brand of Procetofen
Azupharma Brand of Procetofen
BIDD:GT0574
BPBio1_000166
BRD-K50388907-001-05-6
BRN 2062462
BSPBio_000150
BSPBio_003162
Bouchara Brand of Procetofen
C07586
C20H21ClO4
CAS-49562-28-9
CCRIS 7282
CHEBI:5001
CHEMBL672
CID3339
CIP-Fenofibrate
CPD000058299
Controlip
D00565
D011345
DB01039
Debat, Fenofibrate
DivK1c_000557
EINECS 256-376-3
EU-0100486
Elasterate
Elasterin
F 6020
F6020_SIGMA
FENOFIBRATE (MICRONIZED)
FNF
Fenobeta
Fenobrate
Fenofanton
Fenofibrat AL
Fenofibrat AZU
Fenofibrat AbZ
Fenofibrat FPh
Fenofibrat Heumann
Fenofibrat Hexal
Fenofibrat Stada
Fenofibrat ratiopharm
Fenofibrat-ratiopharm
Fenofibrate
Fenofibrate (JAN/INN)
Fenofibrate Debat
Fenofibrate IDD-P
Fenofibrate MSD
Fenofibrate [INN:BAN]
Fenofibrato
Fenofibrato [INN-Spanish]
Fenofibratum
Fenofibratum [INN-Latin]
Fenofibric acid
Fenogal
Fenoglide
Fenomax
Fenotard
Finofibrate
Fournier Brand of Procetofen
Fulcro
GNR Pharma Brand of Procetofen
GNR-Pharma Brand of Procetofen
GRS-027
Gate Brand of Procetofen
Gen Fenofibrate
Gen-Fenofibrate
Genpharm Brand of Procetofen
HMS1568H12
HMS1921B17
HMS2090G20
HMS2092B05
HMS501L19
Heumann Brand of Procetofen
Heumann, Fenofibrat
Hexal Brand of Procetofen
Hexal, Fenofibrat
I06-0048
IDI1_000557
Isopropyl (4'-(P-chlorobenzoyl)-2-phenoxy-2-methyl)propionate
Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate
Isopropyl 2-(p-(p-chlorobenzoyl)phenoxy)-2-methylpropionate
KBio1_000557
KBio2_001730
KBio2_004298
KBio2_006866
KBio3_002382
KBioGR_000706
KBioSS_001730
Knoll Brand of Procetofen
LCP-Feno
LCP-FenoChol
LF 178
 
LF-178
LF178
LS-121256
Lichtenstein Brand of Procetofen
Lipanthyl
Lipantil
Lipantil (TN)
Liparison
Lipidex
Lipidil
Lipidil Micro
Lipidil Supra
Lipidil Ter
Lipidil-Ter
Lipifen
Lipirex
Lipoclar
Lipofen
Lipofen (TN)
Lipofene
Liposit
Lipsin
Lofibra
Lopac-F-6020
Lopac0_000486
Luxacor
MLS000028515
MLS001148191
MTW Brand of Procetofen
MTW Fenofibrat
MTW-Fenofibrat
Merck dura Brand of Procetofen
Micronized Procetofen, Antara
MolPort-002-887-051
NCGC00015437-01
NCGC00015437-02
NCGC00015437-03
NCGC00015437-06
NCGC00015437-12
NCGC00021475-03
NCGC00021475-04
NCGC00021475-05
NCGC00021475-06
NCGC00021475-07
NCGC00021475-08
NINDS_000557
NSC 281319
NSC281319
Nolipax
Novartis Brand of Procetofen
Novo Fenofibrate
Novo-Fenofibrate
Novopharm Brand of Procetofen
Nu Fenofibrate
Nu Pharm Brand of Procetofen
Nu-Fenofibrate
Nu-Pharm Brand of Procetofen
PMS Fenofibrate Micro
PMS-Fenofibrate Micro
Pharmascience Brand of Procetofen
Pharmavit
Phenofibrate
Prestwick0_000275
Prestwick1_000275
Prestwick2_000275
Prestwick3_000275
Prestwick_217
Procetofen
Procetofen Reliant Brand
Procetofen, Antara Micronized
Procetofene
Proctofene
Protolipan
Q Pharm Brand of Procetofen
Q-Pharm Brand of Procetofen
Reliant Brand of Procetofen
S1794_Selleck
SAM002264613
SMR000058299
SPBio_001380
SPBio_002369
SPECTRUM1501010
ST085313
Schering Plough Brand of Procetofen
Schering-Plough Brand of Procetofen
Secalip
Sedufen
Spectrum2_001390
Spectrum3_001431
Spectrum4_000413
Spectrum5_001479
Spectrum_001250
Stada, Fenofibrat
Stadapharm Brand of Procetofen
Supralip
TL8003296
TRICOR (MICRONIZED)
Tricor
Tricor (TN)
Triglide
Triglide (TN)
Trilipix
UNII-U202363UOS
United Drug Brand of Procetofen
ZINC00584092
betapharm Brand of Procetofen
ct Arzneimittel Brand of Procetofen
ct-Arzneimittel Brand of Procetofen
durafenat
fenofibrat von ct
fenofibrate
fenofibric acid
isopropyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate
nchembio790-comp24
ratiopharm Brand of Procetofen
10
RamiprilapprovedPhase 415187333-19-55362129
Synonyms:
(2 S ,3 aS ,6 aS )-1[( S )-N-[( S )-1-Carboxy-3-phenylpropyl] alanyl] octahydrocyclopenta [ b ]pyrrole-2-carboxylic acid, 1-ethyl ester
(2S,3aS,6aS)-1-((S)-2-((S)-1-ethoxy-1-oxo-4-phenylbutan-2-ylamino)propanoyl) octahydrocyclopenta[b]pyrrole-2-carboxylic acid
(2S,3aS,6aS)-1-((S)-N-((S)-1-Carboxy-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid, 1-ethyl ester
(2S,3aS,6aS)-1-((S)-N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrol-2-carbonsaeure
(2S,3aS,6aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid
(2S,3aS,6aS)-1-[(2S)-2-{[(1S)-1-ethoxycarbonyl-3-phenylpropyl]amino}propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid
(2S,3aS,6aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid (non-preferred name)
(2S-(1(R*(R*)),2alpha,3abeta,6abeta))-1-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid.
(2S-(1(R*(r*)),2alpha,3abeta,6abeta))-1-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid
(2s,3as,6as)-1((s)-n-((s)-1-carboxy-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrole-2-carboxylic
(2s,3as,6as)-1-((s)-2-((s)-1-ethoxy-1-oxo-4-phenylbutan-2-ylamino)propanoyl)-octahydrocyclopenta[b]p
(2s,3as,6as)-1-[(s)-2-((s)-1-ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]
126613-39-6
87333-19-5
AC-1347
AC1NSFPR
Acovil
Almirall Brand of Ramipril
Altace
Altace (TN)
Altace (tn)
Astra Brand of Ramipril
AstraZeneca Brand of Ramipril
Aventis Brand of Ramipril
Aventis Pharma Brand of Ramipril
BIDD:GT0803
BSPBio_003347
Bio-0651
C23H32N2O5
CHEBI:289203
CHEBI:8774
CHEMBL1168
CID5362129
CPD000466386
Carasel
Cardace
D00421
D017257
DB00178
Delix
HMS2051E04
HMS2090L11
HMS2093M10
HOE 498
HOE498
Hoe-498
Hoechst Brand of Ramipril
 
Hypren
Hytren
KBio2_002504
KBio2_005072
KBio2_007640
KBio3_002849
KBioGR_001858
KBioSS_002512
LS-58199
Lostapres
MLS000759523
MLS001216547
MLS001423965
MolPort-001-736-571
Monarch Brand of Ramipril
N-(1S-carboethoxy-3-phenylpropyl)-S-alanyl-cis,endo-2-azabicyclo[3.3.0]octane-3S-carboxylic Acid
NCGC00178127-01
Naprix
Pramace
Pramace (discontinued)
Promed Brand of Ramipril
Quark
R0404_SIGMA
Ramace
Ramipril
Ramipril (USP/INN)
Ramipril [USAN:INN:BAN]
Ramiprilum
Ramiprilum [Latin]
Ramipro, Tritace, Altace, Prilace, Ramipril
S1793_Selleck
SAM001246757
SAM002699899
SMR000466386
SPECTRUM1505214
STK801937
Spectrum3_001794
Spectrum4_001269
Spectrum5_001721
Spectrum_001958
Triatec
Tritace
UNII-L35JN3I7SJ
Unipril
Vesdil
Zabien
[2S,3aS,6aS]-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid
[2s,3as,6as]-1-[(2s)-2-[[(1s)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopen
ramipril
11
GlimepirideapprovedPhase 423093479-97-13476
Synonyms:
1-((p-(2-(3-Ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl)phenyl)sulfonyl)-3-(trans-4-methylcyclohexyl)urea
1-{[4-(2-{[(3-ethyl-4-methyl-2-oxo-2,5-dihydro-1H-pyrrol-1-yl)carbonyl]amino}ethyl)phenyl]sulfonyl}-3-(trans-4-methylcyclohexyl)urea
3-ethyl-4-methyl-N-[2-(4-{[(trans-4-methylcyclohexyl)carbamoyl]sulfamoyl}phenyl)ethyl]-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide
3-ethyl-4-methyl-n-(4-(n-((1r,4r)-4-methylcyclohexylcarbamoyl)sulfamoyl)phenethyl)-2-oxo-2,5-dihydro
4-ethyl-3-methyl-N-[2-[4-[(4-methylcyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide
64598P
93479-97-1
AB00513874
AC-476
AC1L1G0T
Amarel
Amaryl
Amaryl (TN)
Amaryl, Glista OD, Glimepiride
Avaglim
BPBio1_000751
BRD-K34776109-001-03-4
BRD-K42693031-001-01-8
BRN 5365754
BSPBio_000681
Bio-0049
C07669
C24H34N4O5S
CAS-93479-97-1
CCRIS 7083
CHEBI:5383
CHEMBL1481
CID3476
CPD000466368
D00593
DB00222
Endial
G2295_SIGMA
Glimepirid
Glimepirida
Glimepirida [Spanish]
Glimepiride (JAN/USP/INN)
Glimepiride [USAN:BAN:INN]
Glimepiridum
Glimepiridum [Latin]
 
Glimepride
Glimer
Glimépiride
Glymepirid
HMS1570C03
HMS2052L03
HMS2090K18
HOE 490
Hoe-490
I06-0029
I06-2285
LS-136752
MLS000759495
MLS001076674
MLS001401419
MolPort-003-847-587
MolPort-003-987-461
MolPort-005-941-721
NCGC00016960-01
NCGC00161404-01
NCGC00161404-02
NCGC00181757-01
Novo-glimepiride
Oprea1_382896
PMS-glimepiride
Prestwick0_000651
Prestwick1_000651
Prestwick2_000651
Prestwick3_000651
Ratio-glimepiride
Roname
S1344_Selleck
SAM001246710
SMR000466368
SPBio_002602
Sandoz glimepiride
Solosa
TL8005924
UNII-6KY687524K
ZINC00537791
glimepiride
12Hypoglycemic AgentsPhase 4, Phase 3, Phase 2, Phase 15733
13Angiotensin Receptor AntagonistsPhase 4, Phase 21173
14Angiotensin II Type 1 Receptor BlockersPhase 4, Phase 21078
15
Angiotensin IIPhase 4, Phase 2116268521-88-0, 11128-99-7172198, 65143
Synonyms:
1-8-Angiotensin I
1-L-Aspasaginyl-5-L-valyl angiotensin octapeptide
Ang II
Angiotensin 2
Angiotensin II (human)
 
Angiotensin II (mouse)
Angiotonin
Asp-arg-val-TYR-ile-his-pro-phe
Human angiotensin II
Hypertensin
Ile(5)-angiotensin II
162,4-thiazolidinedionePhase 4, Phase 2100
17AngiotensinogenPhase 4, Phase 21161
18insulinPhase 4, Phase 3, Phase 24524
19Insulin, Globin ZincPhase 4, Phase 3, Phase 24523
20Antihypertensive AgentsPhase 4, Phase 24095
21Angiotensin-Converting Enzyme InhibitorsPhase 4711
22Analgesics, Non-NarcoticPhase 4, Phase 2, Early Phase 16260
23AnalgesicsPhase 4, Phase 1, Phase 2, Early Phase 111287
24Vasodilator AgentsPhase 43438
25Anticholesteremic AgentsPhase 41983
26Rosuvastatin CalciumPhase 4459147098-20-2
27SympatholyticsPhase 4555
28Adrenergic beta-AntagonistsPhase 41154
29Adrenergic AntagonistsPhase 41535
30Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 3, Phase 2, Early Phase 112767
31AntipyreticsPhase 41534
32Sitagliptin PhosphatePhase 4, Phase 3416
33HormonesPhase 4, Phase 3, Phase 2, Early Phase 113979
34Hormone AntagonistsPhase 4, Phase 3, Phase 2, Early Phase 112778
35
protease inhibitorsPhase 4, Phase 35320
Synonyms:
 
protease inhibitors
36Adrenergic AgentsPhase 45140
37Dipeptidyl-Peptidase IV InhibitorsPhase 4, Phase 3846
38Adrenergic beta-1 Receptor AntagonistsPhase 4350
39IncretinsPhase 4, Phase 31537
40Cyclooxygenase InhibitorsPhase 4, Phase 2, Early Phase 12778
41diureticsPhase 41372
42Platelet Aggregation InhibitorsPhase 42419
43HIV Protease InhibitorsPhase 4, Phase 35319
44Calcium, DietaryPhase 45525
45Anti-Inflammatory Agents, Non-SteroidalPhase 4, Phase 2, Early Phase 14295
46Antirheumatic AgentsPhase 4, Phase 2, Phase 3, Phase 1, Early Phase 110627
47AntimetabolitesPhase 4, Phase 3, Phase 211774
48Autonomic AgentsPhase 4, Phase 1, Phase 29774
49Hydroxymethylglutaryl-CoA Reductase InhibitorsPhase 41956
50Fibrinolytic AgentsPhase 42317

Interventional clinical trials:

(show top 50)    (show all 113)
idNameStatusNCT IDPhase
1Observational Study to Assess Glycosylated Hemoglobin Changes After 6 Months of Treatment With Pioglitazone.CompletedNCT00449553Phase 4
2Efficacy Study of Pioglitazone and Metformin and Association Between Pioglitazone Response and Peroxisome Proliferator-activated Receptor Gamma Gene Variants in Bangladeshi Type 2 Diabetes Mellitus SubjectsCompletedNCT01589445Phase 4
3Peroxisome Proliferator-Activated Receptor-Gamma Activation in Peritoneal Dialysis PatientsCompletedNCT00745225Phase 4
4Effect of Pioglitazone on Insulin Resistance, Atherosclerosis Progression and Clinical Course of Coronary Heart DiseaseCompletedNCT03011775Phase 4
5The Effects of Peroxisome Proliferators Activated Receptor-Gamma (PPAR-γ) Agonists on Certain Biochemical and Inflammatory Markers in Metabolic SyndromeCompletedNCT00926341Phase 4
6A 24 Week, Multicenter, Prospective, Open-labeled, Single-arm, Exploratory Phase 4 Clinical Trial to Evaluate the Safety and Efficacy of Lobeglitazone in Decreasing Intrahepatic Fat Contents in Type 2 Diabetes With NAFLDCompletedNCT02285205Phase 4
7Comparison of Effects of Telmisartan and Valsartan on Neointima Volume in DiabetesCompletedNCT00599885Phase 4
8The Effect of a Peroxisome Proliferator-activated Receptor (PPAR) Alpha Agonist on Cytochrome P450 (CYP) Monooxygenase Activity in HumansCompletedNCT00872599Phase 4
9A Portion-controlled Diet Will Prevent Weight Gain in Diabetics Treated With ACTOSCompletedNCT00219440Phase 4
10Triple Combination Therapy in Type 2 Diabetic Patients Who Had Inadequate Glycemic Control With Combination TherapyRecruitingNCT02338921Phase 4
11Rosiglitazone Plaque StudyUnknown statusNCT00123227Phase 3
12Compassionate Treatment of Patients With Inborn Errors of Bile Acid Metabolism With Cholic AcidCompletedNCT00007020Phase 3
13Betaine and Peroxisome Biogenesis DisordersCompletedNCT01838941Phase 3
14Stem Cell Transplant for Inborn Errors of MetabolismCompletedNCT00176904Phase 2, Phase 3
15PPAR-gamma Agonists, Rheumatoid Arthritis and Cardiovascular DiseaseCompletedNCT00554853Phase 3
16Role of Rosiglitazone on Pre-Diabetes Mellitus and Coronary Artery DiseaseCompletedNCT01574820Phase 3
17Effect of Pioglitazone Administered to Patients With Friedreich's Ataxia: Proof of ConceptCompletedNCT00811681Phase 3
18Effects of Pioglitazone on High-density Lipoprotein (HDL) Function in Persons With DiabetesCompletedNCT01156597Phase 3
19Sitagliptin Metformin/PPARg Agonist Combination Therapy Add-on (0431-052)CompletedNCT00350779Phase 3
20MD1003-AMN MD1003 in AdrenomyeloneuropathyActive, not recruitingNCT02961803Phase 2, Phase 3
21A Phase 2/3 Study of the Efficacy and Safety of Hematopoietic Stem Cells Transduced With Lenti-D Lentiviral Vector for the Treatment of Cerebral Adrenoleukodystrophy (CALD)Active, not recruitingNCT01896102Phase 2, Phase 3
22Effect of Glycerol Trierucate on Clinical Course of AdrenoleukodystrophySuspendedNCT00004418Phase 2, Phase 3
23A Phase III Trial of Lorenzo's Oil in AdrenomyeloneuropathyTerminatedNCT00545597Phase 3
24ALD-101 Adjuvant Therapy of Unrelated Umbilical Cord Blood Transfusion (UCBT) in Patients With Inherited Metabolic DiseasesTerminatedNCT00654433Phase 3
25Endometriosis: ImmunomodulationWithdrawnNCT01184144Phase 2, Phase 3
26Effect of Rosiglitazone on Peritoneal Cytokines in Women With EndometriosisWithdrawnNCT00121953Phase 2, Phase 3
27HSCT for High Risk Inherited Inborn ErrorsCompletedNCT00383448Phase 2
28A Clinical Trial for AMN: Validation of Biomarkers of Oxidative Stress, Efficacy and Safety of a Mixture of AntioxidantsCompletedNCT01495260Phase 2
29Canakinumab in Patients With Active Hyper-IgD SyndromeCompletedNCT01303380Phase 2
30Rosiglitazone in the Treatment of HIV-Associated HyperlipidemiaCompletedNCT00006493Phase 2
31Substrate Cycling in Energy MetabolismCompletedNCT00361751Phase 2
32Telmisartan Versus Losartan in Kidney TransplantationCompletedNCT01224860Phase 2
33Pioglitazone for Heroin and for Nicotine DependenceCompletedNCT01395797Phase 1, Phase 2
34Treating Nonalcoholic Steatohepatitis With PioglitazoneCompletedNCT00062764Phase 2
35Treatment of Nonalcoholic Steatohepatitis With PioglitazoneCompletedNCT00013598Phase 2
36A Mechanistic Study of the Effects of LY518674 on High-Density Lipoprotein Cholesterol (HDL-C) MetabolismCompletedNCT00327002Phase 2
37Study to Evaluate the Safety and Analgesic Activity of ATx08-001 in Subjects With Postherpetic NeuralgiaCompletedNCT01318226Phase 2
38A Clinical Trial to Evaluate the Safety and Efficacy of ZYH7 Compared to Fenofibrate in Patients With DyslipidemiaCompletedNCT01539616Phase 2
39Effects of KDT501 on Metabolic Features in Insulin Resistant SubjectsCompletedNCT02444910Phase 2
40A Placebo Controlled Safety and Efficacy Study of INT131 Besylate in Type 2 Diabetes, With an Active ComparatorCompletedNCT00631007Phase 2
41Placebo Controlled Dose-Response Study of Rivoglitazone in Type 2 DiabetesCompletedNCT00575471Phase 2
42Placebo and Active Comparator Controlled Dose Response Study of Rivoglitazone in Type 2 DiabetesCompletedNCT00575874Phase 2
43A Randomized, Placebo-Controlled, Double-Blind Pilot Study of Pioglitazone Hydrochloride in Severe, Refractory AsthmaCompletedNCT00994175Phase 2
44MT2013-31: Allo HCT for Metabolic Disorders and Severe OsteopetrosisRecruitingNCT02171104Phase 2
45A Pilot Study of Vitamin D in Boys With X-linked AdrenoleukodystrophyRecruitingNCT02595489Phase 1, Phase 2
46Autologous Hematopoietic Stem Cell Gene Therapy for Metachromatic Leukodystrophy and AdrenoleukodystrophyRecruitingNCT02559830Phase 1, Phase 2
47Nutrition, Inflammation and Insulin Resistance in End Stage Renal Disease-Aim 2RecruitingNCT02278562Phase 2
48Phase 2b Study in NASH to Assess IVA337RecruitingNCT03008070Phase 2
49Efatutazone Dihydrochloride in Treating Patients With Previously Treated Myxoid Liposarcoma That Cannot Be Removed by SurgeryRecruitingNCT02249949Phase 2
50A Trial With Metronomic Low-dose Treosulfan, Pioglitazone and Clarithromycin Versus Standard Treatment in NSCLCRecruitingNCT02852083Phase 2

Search NIH Clinical Center for Peroxisome Disorders

Genetic Tests for Peroxisome Disorders

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Anatomical Context for Peroxisome Disorders

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MalaCards organs/tissues related to Peroxisome Disorders:

35
Kidney, Skeletal muscle, Heart, Bone, Ovary, Liver, Monocytes

Animal Models for Peroxisome Disorders or affiliated genes

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MGI Mouse Phenotypes related to Peroxisome Disorders:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053899.0ABCD1, AGPS, GNPAT, HSD17B4, PEX5, PEX7
2MP:00053799.0ABCD1, AGPS, GNPAT, HSD17B4, PEX2, PEX5
3MP:00053918.8ABCD1, AGPS, GNPAT, HSD17B4, PEX1, PEX7
4MP:00053708.4HADHB, HSD17B4, PEX1, PEX11B, PEX2, PEX5
5MP:00036318.2ABCD1, GNPAT, HSD17B4, PEX1, PEX11B, PEX2
6MP:00053788.2GNPAT, HADHB, HSD17B4, PEX1, PEX11B, PEX2
7MP:00107687.5AGPS, CAT, GNPAT, HADHB, HSD17B4, PEX1
8MP:00053766.5ABCD1, AGPS, AGXT, CAT, GNPAT, HADHB

Publications for Peroxisome Disorders

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Articles related to Peroxisome Disorders:

(show top 50)    (show all 55)
idTitleAuthorsYear
1
Safety of long-term restrictive diets for peroxisomal disorders: vitamin and trace element status of patients treated for Adult Refsum Disease. (26799636)
2016
2
A peroxisomal disorder of severe intellectual disability, epilepsy, and cataracts due to fatty acyl-CoA reductase 1 deficiency. (25439727)
2014
3
Defective lipid remodeling of GPI anchors in peroxisomal disorders, Zellweger syndrome, and rhizomelic chondrodysplasia punctata. (22253471)
2012
4
Phytanic acid and pristanic acid, branched-chain fatty acids associated with Refsum disease and other inherited peroxisomal disorders, mediate intracellular Ca2+ signaling through activation of free fatty acid receptor GPR40. (21570468)
2011
5
Visual follow-up in peroxisomal-disorder patients treated with docosahexaenoic Acid ethyl ester. (19933185)
2010
6
Investigational methods for peroxisomal disorders. (18633975)
2008
7
Peroxisomal disorders affecting phytanic acid alpha-oxidation: a review. (17956237)
2007
8
Combined liquid chromatography-tandem mass spectrometry as an analytical method for high throughput screening for X-linked adrenoleukodystrophy and other peroxisomal disorders: preliminary findings. (16828324)
2006
9
High incidence of hyperoxaluria in generalized peroxisomal disorders. (16621644)
2006
10
Peroxisomal disorders I: biochemistry and genetics of peroxisome biogenesis disorders. (15679822)
2005
11
Metabolic and molecular basis of peroxisomal disorders: a review. (15098234)
2004
12
The TRIM37 gene encodes a peroxisomal RING-B-box-coiled-coil protein: classification of mulibrey nanism as a new peroxisomal disorder. (11938494)
2002
13
Refsum's disease: a peroxisomal disorder affecting phytanic acid alpha-oxidation. (11948235)
2002
14
Stereochemistry of the peroxisomal branched-chain fatty acid alpha- and beta-oxidation systems in patients suffering from different peroxisomal disorders. (11893780)
2002
15
The neurobiology of X-linked adrenoleukodystrophy, a demyelinating peroxisomal disorder. (10088993)
1999
16
Stability of alkyl-dihydroxyacetonephosphate synthase in human control and peroxisomal disorder fibroblasts. (10683770)
1999
17
X-linked dominant chondrodysplasia punctata: a peroxisomal disorder? (9677071)
1998
18
New insights in peroxisomal beta-oxidation. Implications for human peroxisomal disorders. (9803880)
1998
19
Cholesterol biosynthesis, peroxisomes and peroxisomal disorders: mevalonate kinase is not only deficient in Zellweger syndrome but also in rhizomelic chondrodysplasia punctata. (9686383)
1998
20
Developmental delay and growth failure caused by a peroxisomal disorder, dihydroxyacetonephosphate acyltransferase (DHAP-AT) deficiency. (9843043)
1998
21
Characterization of phytanoyl-Coenzyme A hydroxylase in human liver and activity measurements in patients with peroxisomal disorders. (9565335)
1998
22
Molecular analysis of peroxisomal disorders]. (9545777)
1998
23
Immunological localization and tissue distribution of alkyldihydroxyacetonephosphate synthase and deficiency of the enzyme in peroxisomal disorders. (9266692)
1997
24
D-3-hydroxyacyl-CoA dehydratase/D-3-hydroxyacyl-CoA dehydrogenase bifunctional protein deficiency: a newly identified peroxisomal disorder. (9345094)
1997
25
On the molecular etiology of decreased arachidonic (20:4n-6), docosapentaenoic (22:5n-6) and docosahexaenoic (22:6n-3) acids in Zellweger syndrome and other peroxisomal disorders. (9062899)
1997
26
Peroxisomal disorders: clinical aspects. (8993563)
1996
27
Infantile Refsum disease: neonatal cholestatic jaundice presentation of a peroxisomal disorder. (7533834)
1995
28
Immunolocalization of a 43 kDa peroxisomal membrane protein in the liver of patients with generalized peroxisomal disorders. (8521871)
1995
29
Human peroxisomal targeting signal-1 receptor restores peroxisomal protein import in cells from patients with fatal peroxisomal disorders. (7790377)
1995
30
Prenatal diagnosis of peroxisomal disorders. Biochemical and immunocytochemical studies on peroxisomes in human amniocytes. (8059925)
1994
31
Human alkyldihydroxyacetonephosphate synthase deficiency: a new peroxisomal disorder. (7807941)
1994
32
Peroxisome disorders and cutaneous manifestations. (8305747)
1994
33
Peroxisomal disorders in children: immunohistochemistry and neuropathology. (8463903)
1993
34
Lactic acidosis and mitochondrial dysfunction in two children with peroxisomal disorders. (8105143)
1993
35
Peroxisomal abnormality in fibroblasts from involved skin of CHILD syndrome. Case study and review of peroxisomal disorders in relation to skin disease. (1519936)
1992
36
Infantile refsum disease: gastrointestinal presentation of a peroxisomal disorder. (1374125)
1992
37
Bifunctional enzyme deficiency: identification of a new type of peroxisomal disorder in a patient with an impairment in peroxisomal beta-oxidation of unknown aetiology by means of complementation analysis. (1357231)
1992
38
Very large peroxisomes in distinct peroxisomal disorders (rhizomelic chondrodysplasia punctata and acyl-CoA oxidase deficiency): novel data. (1750197)
1991
39
Genetic relationship between the Zellweger syndrome and other peroxisomal disorders characterized by an impairment in the assembly of peroxisomes. (2183242)
1990
40
Analysis of very long-chain fatty acids and plasmalogen in the erythrocyte membrane: a simple method for the detection of peroxisomal disorders and discrimination between adrenoleukodystrophy and Zellweger syndrome. (2234315)
1990
41
Mitochondrial oxidation of phytanic acid in human and monkey liver: implication that Refsum's disease is not a peroxisomal disorder. (1690986)
1990
42
Pathology of hepatic peroxisomes and mitochondria in patients with peroxisomal disorders. (1689088)
1990
43
Molecular analysis of peroxisomal beta-oxidation enzymes in infants with Zellweger syndrome and Zellweger-like syndrome: further heterogeneity of the peroxisomal disorder. (2452040)
1988
44
A new peroxisomal disorder with enlarged peroxisomes and a specific deficiency of acyl-CoA oxidase (pseudo-neonatal adrenoleukodystrophy). (2894756)
1988
45
Infantile Refsum disease: an inherited peroxisomal disorder. Comparison with Zellweger syndrome and neonatal adrenoleukodystrophy. (2445576)
1987
46
Peroxisomal very long-chain fatty acid beta-oxidation in human skin fibroblasts: activity in Zellweger syndrome and other peroxisomal disorders. (2441904)
1987
47
The cerebro-hepato-renal (Zellweger) syndrome and other peroxisomal disorders. (3319743)
1987
48
Peroxisomal fatty acid beta-oxidation in relation to the accumulation of very long chain fatty acids in cultured skin fibroblasts from patients with Zellweger syndrome and other peroxisomal disorders. (3680527)
1987
49
Prenatal diagnosis of Zellweger syndrome by measurement of very long chain fatty acid (C26:0) beta-oxidation in cultured chorionic villous fibroblasts: implications for early diagnosis of other peroxisomal disorders. (3652452)
1987
50
Rhizomelic chondrodysplasia punctata: another peroxisomal disorder. (4010717)
1985

Variations for Peroxisome Disorders

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Expression for genes affiliated with Peroxisome Disorders

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Search GEO for disease gene expression data for Peroxisome Disorders.

Pathways for genes affiliated with Peroxisome Disorders

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GO Terms for genes affiliated with Peroxisome Disorders

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Cellular components related to Peroxisome Disorders according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1integral component of peroxisomal membraneGO:00057799.6ABCD1, PEX11B, PEX2, SLC25A17
2intracellular membrane-bounded organelleGO:00432318.8AGPS, CAT, HSD17B4, PEX1, SLC25A17
3peroxisomal matrixGO:00057828.6AGPS, AGXT, CAT, GNPAT, HSD17B4, PEX7
4peroxisomal membraneGO:00057787.4ABCD1, AGPS, CAT, GNPAT, HSD17B4, PEX1
5mitochondrionGO:00057397.4ABCD1, AGPS, AGXT, CAT, GNPAT, HADHB
6membraneGO:00160207.2ABCD1, AGPS, CAT, GNPAT, HSD17B4, PEX11B
7peroxisomeGO:00057776.0ABCD1, AGPS, AGXT, CAT, GNPAT, HSD17B4

Biological processes related to Peroxisome Disorders according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1alpha-linolenic acid metabolic processGO:003610910.4ABCD1, HSD17B4
2fatty acid beta-oxidation using acyl-CoA oxidaseGO:003354010.2ABCD1, HSD17B4
3protein targeting to peroxisomeGO:000662510.2PEX1, PEX7
4fatty acid alpha-oxidationGO:000156110.1PHYH, SLC25A17
5ether lipid biosynthetic processGO:000861110.0AGPS, GNPAT, PEX7
6response to fatty acidGO:00705429.8CAT, GNPAT
7protein import into peroxisome matrixGO:00165589.6PEX1, PEX2, PEX5, PEX7
8very long-chain fatty acid metabolic processGO:00000389.5HSD17B4, PEX2
9peroxisome organizationGO:00070318.8ABCD1, PEX1, PEX11B, PEX2, PEX5, PEX7
10fatty acid beta-oxidationGO:00066358.1ABCD1, HADHB, HSD17B4, PEX2, PEX5, PEX7

Molecular functions related to Peroxisome Disorders according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
13-hydroxyacyl-CoA dehydrogenase activityGO:000385710.4HADHB, HSD17B4
2enzyme bindingGO:00198999.2ABCD1, CAT, PEX5, PEX7
3receptor bindingGO:00051028.6AGXT, CAT, GNPAT, HSD17B4
4protein homodimerization activityGO:00428037.8ABCD1, AGXT, CAT, HSD17B4, PEX11B, PEX7

Sources for Peroxisome Disorders

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet