Aliases & Classifications for Persistent Vegetative State

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Sources:
46NINDS, 47Novoseek, 65UMLS
See all MalaCards sources

Aliases & Descriptions for Persistent Vegetative State:

Name: Persistent Vegetative State 46 47 65

External Ids:

UMLS65 C0242670

Summaries for Persistent Vegetative State

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NINDS:46 A coma, sometimes also called persistent vegetative state, is a profound or deep state of unconsciousness. Persistent vegetative state is not brain-death. An individual in a state of coma is alive but unable to move or respond to his or her environment. Coma may occur as a complication of an underlying illness, or as a result of injuries, such as head trauma. . Individuals in such a state have lost their thinking abilities and awareness of their surroundings, but retain non-cognitive function and normal sleep patterns. Even though those in a persistent vegetative state lose their higher brain functions, other key functions such as breathing and circulation remain relatively intact. Spontaneous movements may occur, and the eyes may open in response to external stimuli. Individuals may even occasionally grimace, cry, or laugh. Although individuals in a persistent vegetative state may appear somewhat normal, they do not speak and they are unable to respond to commands.

MalaCards based summary: Persistent Vegetative State is related to oculomotor apraxia cogan type and cerebritis, and has symptoms including disturbance of consciousness, other alteration of consciousness and transient alteration of awareness. An important gene associated with Persistent Vegetative State is SLC25A22 (Solute Carrier Family 25 Member 22). Affiliated tissues include brain, eye and lung, and related mouse phenotype taste/olfaction.

Wikipedia:68 A persistent vegetative state (PVS) is a disorder of consciousness in which patients with severe brain... more...

Related Diseases for Persistent Vegetative State

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Diseases related to Persistent Vegetative State via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 23)
idRelated DiseaseScoreTop Affiliating Genes
1oculomotor apraxia cogan type10.4
2cerebritis10.2
3epileptic encephalopathy, early infantile, 310.2
4subacute sclerosing panencephalitis10.2
5brain injury10.1
6traumatic brain injury10.1
7dementia10.1
8head injury10.0
9vascular dementia9.9
10hypoglycemia9.9
11alzheimer disease9.8
12anencephaly9.8
13locked-in syndrome9.8
14ischemia9.8
15sleep disorder9.8
16dystonia9.8
17neuronitis9.8
18encephalitis9.8
19anoxia9.8
20stroke, ischemic9.7APOE, ENO2
21encephalitozoonosis9.6APOE, ENO2
22gerstmann-straussler disease9.4APOE, ENO2
23pinched nerve8.4APOE, ENO2, GABBR1, SLC25A22

Comorbidity relations with Persistent Vegetative State via Phenotypic Disease Network (PDN):


Heart DiseaseAcute Cystitis
Decubitus Ulcer

Graphical network of the top 20 diseases related to Persistent Vegetative State:



Diseases related to persistent vegetative state

Symptoms for Persistent Vegetative State

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UMLS symptoms related to Persistent Vegetative State:


disturbance of consciousness, other alteration of consciousness, transient alteration of awareness, syncope

Drugs & Therapeutics for Persistent Vegetative State

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Drugs for Persistent Vegetative State (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 18)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
DopamineapprovedPhase 2308462-31-7, 51-61-6681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine Hcl
Dopamine Hydrochloride
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
 
KBio1_000780
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
2
Apomorphineapproved, investigationalPhase 23441372-20-76005
Synonyms:
(-)-10,11-Dihydroxyaporphine
(6AR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol
(6aR)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo(de,g)chinolin-10,11-diol
(6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol
(R)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol
(R)-5,6,6a,7-tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol
(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol
(−)-10,11-dihydroxyaporphine
314-19-2 (hydrochloride anhydrous)
41372-20-7 (hydrochloride hemihydrate)
4H-Dibenzo(de,g)quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, (R)- (9CI)
4H-Dibenzo(de,g)quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-, HCl, (R)-, hemihydrate
58-00-4
6a-beta-Aporphine-10,11-diol
6a-beta-Aporphine-10,11-diol, hydrochloride, hemihydrate
6abeta-Aporphine-10,11-diol
AC1L1LLC
Apokyn
Apomorfin
Apomorphin
Apomorphine (BAN)
Apomorphine HCl hydrate
Apomorphine Hydrochloride
Apomorphine Hydrochloride Hemihydrate
Apomorphine hydrochloride
Apomorphine hydrochloride hemihydrate
Apomorphinium Chloride Hemihydrate
Apomorphinium chloride hemihydrate
Apormorphine
BPBio1_000092
BPBio1_001179
BRD-K76022557-001-01-3
BSPBio_000082
Biomol-NT_000019
C17H17NO2
 
CE0800000
CHEBI:48538
CID6005
D07460
DB00714
EINECS 200-360-0
HMS2089C10
HSDB 3289
IV Apomorphine
Ixense
L-Apomorphine
LS-21474
NCGC00025349-01
NCGC00025349-02
NIOSH/CE0800000
PDSP1_000780
PDSP2_001488
Prestwick0_000101
Prestwick1_000101
Prestwick2_000101
Prestwick3_000101
R-(-)-Apomorphine
R-(−)-apomorphine
SMP1_000027
SPBio_002021
STOCK1N-03149
Tocris-2073
UNII-N21FAR7B4S
Uprima
Uprima (TN)
VR-040
VR-400
VR004
apomorphine
nchembio.307-comp3
nchembio873-comp6
3Pharmaceutical SolutionsPhase 2, Phase 17004
4Dopamine AgentsPhase 23084
5Peripheral Nervous System AgentsPhase 218510
6Neurotransmitter AgentsPhase 214795
7Dopamine AgonistsPhase 2544
8EmeticsPhase 2164
9Gastrointestinal AgentsPhase 26401
10
Amantadineapproved65768-94-52130
Synonyms:
1-Adamantamine
1-Adamantanamine
1-Adamantanamine (8CI)
1-Adamantylamine
1-Aminoadamantane
1-Aminotricyclo(3.3.1.1(sup 3,7))decane
1-adamantanamine
1-adamantylamine
1-aminoadamantane
138576_ALDRICH
665-66-7 (hydrochloride)
768-94-5
AB00514655
AC-11992
AC1L1CZI
AC1Q4UAF
AC1Q5396
ADAMANTANE,1-AMINO
AKOS000113994
AKOS000119324
Adamantamine
Adamantanamine
Adamantylamine
Amant
Amantadina
Amantadina [INN-Spanish]
Amantadine
Amantadine (INN)
Amantadine Base
Amantadine HCL
Amantadine Hydrochloride
Amantadine [INN:BAN]
Amantadine hydrochloride
Amantadine sulfate
Amantadinum
Amantadinum [INN-Latin]
Amantidine
Ambap768-94-5
Aminoadamantane
BIA4304
BIDD:GT0757
BPBio1_000368
BRN 2204333
BSPBio_000334
BSPBio_001570
BSPBio_001822
Bio-0821
C06818
C10H17N
CHEBI:2618
CHEMBL660
CID2130
D07441
DB00915
DivK1c_000815
EINECS 212-201-2
Endantadine
Gen-Amantadine
HMS1791O12
HMS1989O12
HSDB 3202
I14-1101
IDI1_000815
InChI=1/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H
 
KBio1_000815
KBio2_000390
KBio2_002958
KBio2_005526
KBio3_001322
KBioGR_000548
KBioSS_000390
L000868
LS-157049
Lopac-A-1260
Lopac0_000004
Mantadine
MolPort-001-661-700
MolPort-001-760-587
MolPort-001-791-102
NCGC00015036-01
NCGC00015036-07
NCGC00162039-01
NCGC00162039-02
NCGC00162039-03
NCGC00162039-04
NCGC00179597-01
NCIOpen2_001059
NINDS_000815
NSC 341865
NSC341865
NSC83653
OR14310
Oprea1_248648
Pk-merz
Prestwick0_000407
Prestwick1_000407
Prestwick2_000407
Prestwick3_000407
SPBio_000002
SPBio_002273
STK298781
Spectrum2_000081
Spectrum3_000291
Spectrum4_000134
Spectrum5_000772
Spectrum_000030
Symadine
Symmetrel
TCMDC-125869
TL8005280
Tricyclo(3.3.1.1(3,7))-decan-1-amine
Tricyclo(3.3.1.1(sup 3,7))decan-1-amine
Tricyclo(3.3.1.1(sup 3.7))decan-1-amine
Tricyclo(3.3.1.13,7)decan-1-amine
Tricyclo[3.3.1.1(3,7)]decan-1-amine
Tricyclo[3.3.1.1(3,7)]decan-1-ylamine
Tricyclo[3.3.1.1(3,7)]decane-1-amine
Tricyclo[3.3.1.1(sup3,7)]decan-1-amine
Tricyclo[3.3.1.1^3,7]decan-1-amine
UNII-BF4C9Z1J53
Viregyt
Virosol
WLN: L66 B6 A B- C 1B ITJ BZ
Wiregyt
adamantan-1-amine
adamantan-1-ylamine
amantadine
tricyclo[3.3.1.1(3,7)]decan-1-ylamine
tricyclo[3.3.1.1(3,7)]decane-1-amine
tricyclo[3.3.1.1~3,7~]decan-1-amine
11
12Contraceptives, Oral, Combined566
13Contraceptives, Oral3734
14Antiviral Agents8071
15Antiparkinson Agents1312
16Analgesics, Non-Narcotic5184
17Analgesics9358
18Anti-Infective Agents17220

Interventional clinical trials:

(show all 21)
idNameStatusNCT IDPhase
1Vagus Nerve Stimulation to Augment Recovery From Minimally Conscious or Persistently Vegetative States After Traumatic Brain InjuryRecruitingNCT01260090Phase 3
2Transcranial Direct Current Stimulation in Patients With Disorders of ConsciousnessCompletedNCT01673126Phase 2
3The Efficacy of Familiar Voice Stimulation During Coma RecoveryCompletedNCT00557076Phase 1, Phase 2
4tDCS on Precuneus in MCS: Repeated StimulationsCompletedNCT02702362Phase 2
5tDCS in MCS: Repeated StimulationsCompletedNCT02019615Phase 2
6Thalamic Stimulation of Patients in Vegetative or Minimally Conscious StateRecruitingNCT01027572Phase 2
7Fronto-parietal tDCS in Severely Brain Injured Patients With Disorders of ConsciousnessRecruitingNCT02626403Phase 2
8Efficacy Study of NH001 in Vegetative State & Minimally Conscious State Following a Traumatic Brain InjurySuspendedNCT00761228Phase 2
9The Impact of RPh201 on CVS Patients: Clinical and fMRI MeasurementsWithdrawnNCT01417299Phase 1, Phase 2
10The Impact of RPh201 on Chronic Vegetative State (CVS): fMRI StudyRecruitingNCT01438684Phase 1
11Transcranial Direct Current Stimulation Effects in Patients With Chronic Consciousness DisordersRecruitingNCT02288533Phase 1
12Effectiveness of Sensory Stimulation for Person in a Coma or Persistent Vegetative State After Traumatic Brain InjuryCompletedNCT02629588
13A Study to Tailor Advance DirectivesCompletedNCT00121004
14Navigated Brain Stimulation in Diagnosis of Minimally Conscious StateCompletedNCT01467908
15Transcranial Brain Stimulation in Vegetative State PatientsCompletedNCT01820923
16Resuscitation Registry - Surrogate Markers of Outcome After Cardiac ArrestRecruitingNCT02722460
17Study of Conscious Behavior Under Low-frequency Deep Brain Stimulation in Chronic and Severe Post-coma Disorders of ConsciousnessRecruitingNCT01718249
18Beneficial Effects of Music on Cognition and Consciousness LevelRecruitingNCT02742506
19A Pilot Study to Identify Biomarkers Associated With Chronic Traumatic Brain InjuryRecruitingNCT01171131
20Amantadine and Functional Improvement Following ABI Measured by MRI Tractography; A Pilot StudyNot yet recruitingNCT02566720
21Vagal Nerve Stimulation in Coma PatientsNot yet recruitingNCT02591069

Search NIH Clinical Center for Persistent Vegetative State

Genetic Tests for Persistent Vegetative State

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Anatomical Context for Persistent Vegetative State

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MalaCards organs/tissues related to Persistent Vegetative State:

33
Brain, Eye, Lung, T cells, Prostate, Heart, Myeloid

Animal Models for Persistent Vegetative State or affiliated genes

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MGI Mouse Phenotypes related to Persistent Vegetative State:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053949.3APOE, ENO2

Publications for Persistent Vegetative State

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Articles related to Persistent Vegetative State:

(show top 50)    (show all 312)
idTitleAuthorsYear
1
Ethics and Health Policy of Dialyzing a Patient in a Persistent Vegetative State. (24115197)
2013
2
Causes and outcomes of persistent vegetative state in a Chinese versus American referral hospital. (23099847)
2013
3
A long-term intensive behavioral treatment study in patients with persistent vegetative state or minimally conscious state. (21305239)
2011
4
The place of L-dopa/carbidopa in persistent vegetative state. (21060281)
2010
5
Cortical sources of resting-state alpha rhythms are abnormal in persistent vegetative state patients. (19299197)
2009
6
Recognizing a mother's voice in the persistent vegetative state. (17844939)
2007
7
Persistent vegetative state and dementia in the elderly. (17234039)
2007
8
Persistent vegetative state. (17485655)
2007
9
Tube feedings and persistent vegetative state patients: ordinary or extraordinary means? (16830413)
2006
10
Successful neonatal outcome in 2 cases of maternal persistent vegetative state treated in a labor and delivery suite. (16631100)
2006
11
Persistent vegetative state with encephalitis in a pregnant woman with successful fetal outcome. (15924551)
2005
12
Advance directives and the persistent vegetative state in Victoria: a human rights perspective. (16304765)
2005
13
Withdrawing life-sustaining treatment in patients with persistent vegetative state and without an advance directive. (15625919)
2004
14
Ethics roundtable debate: withdrawal of tube feeding in a patient with persistent vegetative state where the patients wishes are unclear and there is family dissension. (15025760)
2004
15
Successful management of multiple sclerosis and persistent vegetative state requires frequent reassessment. (12857365)
2003
16
Withdrawing nutrition and hydration. The Catholic tradition offers guidance for the treatment of patients in a persistent vegetative state. (11763577)
2001
17
Japanese physicians and the care of adult patients in persistent vegetative state. (10786328)
2000
18
CPR for patients in a persistent vegetative state? (9679478)
1998
19
Persistent vegetative state. (9817437)
1998
20
Persistent vegetative state. (9439524)
1998
21
Persistent vegetative state. (9357427)
1997
22
Euthanasia and persistent vegetative state individuals: the role and moral status of autonomy. (15156859)
1996
23
Euthanasia, physician-assisted suicide, and persistent vegetative state. (8757170)
1996
24
Survey of British clinicians' views on management of patients in persistent vegetative state. (8691931)
1996
25
Euthanasia, physician assisted suicide, and persistent vegetative state. (8786683)
1996
26
Persistent vegetative state: important considerations for the neuroscience nurse. (8818986)
1996
27
Euthanasia, physician-assisted suicide, and persistent vegetative state. (8786682)
1996
28
The unmodulated oculocephalic reflex: clinical feature of the persistent vegetative state in the neonate. (8734036)
1996
29
Euthanasia, physician-assisted suicide, and persistent vegetative state. (8757171)
1996
30
The lived experience of registered nurses involved in the withdrawal of nutrition and hydration in a persistent vegetative state (PVS) patient. (7626948)
1995
31
The persistent vegetative state. (7866201)
1995
32
Medical aspects of the persistent vegetative state--a correction. The Multi-Society Task Force on PVS. (7777031)
1995
33
Practice parameters: assessment and management of patients in the persistent vegetative state (summary statement). The Quality Standards Subcommittee of the American Academy of Neurology. (7746375)
1995
34
The persistent vegetative state. (7976218)
1994
35
Withdrawing treatment in the persistent vegetative state. (7935719)
1994
36
Document on the persistent vegetative state by the SocietA Italiana di Neurologia (SIN) Working Group on Bioethics and Neurology. (8125768)
1993
37
Persistent vegetative state and withdrawal of nutrition and hydration. (8331639)
1993
38
Managing patients in a persistent vegetative state. (8401143)
1993
39
Recovery of patients after four months or more in the persistent vegetative state. (8329926)
1993
40
HM-PAO-SPECT in persistent vegetative state after head injury: prognostic indicator of the likelihood of recovery? (2071761)
1991
41
Characterization and modification of brain activity with deep brain stimulation in patients in a persistent vegetative state: pain-related late positive component of cerebral evoked potential. (1705325)
1991
42
The biology of the persistent vegetative state: legal, ethical, and philosophical implications for transplantation. (2349730)
1990
43
Editor's introduction: family privacy and persistent vegetative state. (2628643)
1989
44
Recovery from persistent vegetative state? The case of Carrie Coons. (2501234)
1989
45
Position of the American Academy of Neurology on certain aspects of the care and management of the persistent vegetative state patient. Adopted by the Executive Board, American Academy of Neurology, April 21, 1988, Cincinnati, Ohio. (2909900)
1989
46
A persistent vegetative state. (11653625)
1984
47
Traumatic coma during pregnancy with persistent vegetative state. Case report. (6433967)
1984
48
Termination of treatment in the persistent vegetative state. (11649666)
1984
49
50

Variations for Persistent Vegetative State

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Expression for genes affiliated with Persistent Vegetative State

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Search GEO for disease gene expression data for Persistent Vegetative State.

Pathways for genes affiliated with Persistent Vegetative State

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GO Terms for genes affiliated with Persistent Vegetative State

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Cellular components related to Persistent Vegetative State according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1dendriteGO:00304259.0APOE, GABBR1
2neuronal cell bodyGO:00430258.8ENO2, GABBR1

Sources for Persistent Vegetative State

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet