MCID: PRV011
MIFTS: 19

Pervasive Developmental Disorder Not Otherwise Specified

Categories: Genetic diseases

Aliases & Classifications for Pervasive Developmental Disorder Not Otherwise Specified

MalaCards integrated aliases for Pervasive Developmental Disorder Not Otherwise Specified:

Name: Pervasive Developmental Disorder Not Otherwise Specified 24

Classifications:



Summaries for Pervasive Developmental Disorder Not Otherwise Specified

MalaCards based summary : Pervasive Developmental Disorder Not Otherwise Specified is related to autism susceptibility 16 and autism 9. The drugs Milnacipran and Adrenergic Agents have been mentioned in the context of this disorder. Affiliated tissues include brain and skin.

Wikipedia : 72 A pervasive developmental disorder not otherwise specified (PDD-NOS) is one of the four autism spectrum... more...

Related Diseases for Pervasive Developmental Disorder Not Otherwise Specified

Diseases related to Pervasive Developmental Disorder Not Otherwise Specified via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 22)
id Related Disease Score Top Affiliating Genes
1 autism susceptibility 16 11.1
2 autism 9 11.1
3 autism susceptibility 15 11.1
4 autism 10 11.1
5 autism susceptibility 17 11.1
6 autism 18 11.1
7 autism susceptibility, x-linked 2 11.1
8 autism x-linked 4 11.1
9 autism susceptibility, x-linked 1 11.1
10 autism susceptibility, x-linked 3 11.1
11 autism x-linked 5 11.1
12 autism x-linked 6 11.1
13 asperger syndrome 11.1
14 pervasive developmental disorder 10.9
15 autistic disorder 10.5
16 attention deficit-hyperactivity disorder 10.3
17 epilepsy 10.2
18 anorexia nervosa 10.1
19 obsessive-compulsive disorder 10.1
20 bipolar disorder 10.1
21 anxiety disorder 10.1
22 bruxism 10.1

Graphical network of the top 20 diseases related to Pervasive Developmental Disorder Not Otherwise Specified:



Diseases related to Pervasive Developmental Disorder Not Otherwise Specified

Symptoms & Phenotypes for Pervasive Developmental Disorder Not Otherwise Specified

Drugs & Therapeutics for Pervasive Developmental Disorder Not Otherwise Specified

Drugs for Pervasive Developmental Disorder Not Otherwise Specified (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 45)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Milnacipran Approved Phase 4 92623-85-3 65833
2 Adrenergic Agents Phase 4,Phase 3
3 Atomoxetine Hydrochloride Phase 4,Phase 3
4 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1
5 Neurotransmitter Uptake Inhibitors Phase 4,Phase 3
6 Antidepressive Agents Phase 4
7 Psychotropic Drugs Phase 4
8
Serotonin Phase 4 50-67-9 5202
9 Serotonin Agents Phase 4
10 Serotonin Uptake Inhibitors Phase 4
11
Dopamine Approved Phase 2 51-61-6, 62-31-7 681
12
Memantine Approved, Investigational Phase 2 19982-08-2 4054
13
Acetylcysteine Approved, Investigational Phase 2 616-91-1 12035
14
Benzocaine Approved Phase 2 1994-09-7, 94-09-7 2337
15 tannic acid Approved, Nutraceutical Phase 2
16 Antiparkinson Agents Phase 2
17 Dopamine Agents Phase 2
18 Excitatory Amino Acid Antagonists Phase 2
19 Excitatory Amino Acids Phase 2
20 Antidotes Phase 2
21 Anti-Infective Agents Phase 2
22 Antioxidants Phase 2
23 Antiviral Agents Phase 2
24 Expectorants Phase 2
25 N-monoacetylcystine Phase 2
26 Protective Agents Phase 2
27 Respiratory System Agents Phase 2
28 Omega 3 Fatty Acid Nutraceutical Phase 2
29
Oxytocin Approved, Vet_approved Phase 1 50-56-6 439302 53477758
30
Mecamylamine Approved Phase 1 60-40-2 4032
31 Arginine Vasopressin Phase 1
32 Coagulants Phase 1
33 Hemostatics Phase 1
34 Natriuretic Agents Phase 1
35 Oxytocics Phase 1
36 Vasoconstrictor Agents Phase 1
37 Vasopressins Phase 1
38 Antihypertensive Agents Phase 1
39 Autonomic Agents Phase 1
40 Cholinergic Agents Phase 1
41 Cholinergic Antagonists Phase 1
42 Peripheral Nervous System Agents Phase 1
43 arginine Nutraceutical Phase 1
44 Antibodies
45 Immunoglobulins

Interventional clinical trials:

(show all 24)

id Name Status NCT ID Phase Drugs
1 Atomoxetine, Placebo and Parent Management Training in Autism Completed NCT00844753 Phase 4 atomoxetine;Placebo
2 Milnacipran in Autism and the Functional Locus Coeruleus and Noradrenergic Model of Autism Completed NCT01337700 Phase 4 Milnacipran;Placebo
3 Effectiveness of Atomoxetine in Treating ADHD Symptoms in Children and Adolescents With Autism Completed NCT00498173 Phase 3 Atomoxetine;Placebo
4 Psychotherapy for Anxiety in Children With Autism Spectrum Disorder Recruiting NCT02028247 Phase 3
5 Open Label Extension Study of STX209 (Arbaclofen) in Autism Spectrum Disorders Terminated NCT01706523 Phase 3 STX209 (arbaclofen)
6 Deep rTMS (Repetitive Transcranial Magnetic Stimulation)for Treatment of Autism Symptoms in Children. Unknown status NCT01388179 Phase 2
7 An Open-Label Safety Study of Memantine in Pediatric Patients With Autism, Asperger's Disorder, or Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS) Completed NCT01592786 Phase 2 Memantine Hydrochloride (HCl)
8 Withdrawal Study of Memantine in Pediatric Patients With Autism, Asperger's Disorder, or Pervasive Developmental Disorder Not Otherwise Specified Previously Treated With Memantine Completed NCT01592747 Phase 2 Memantine Hydrochloride (HCl);Memantine Hydrochloride (HCl);Placebo capsules
9 Cognitive Behavioral Therapy (CBT) for Anxiety Disorders in Autism: Adapting Treatment for Adolescents Completed NCT01177969 Phase 1, Phase 2
10 A Study of Oral N-Acetylcysteine in Children With Autism Spectrum Disorders Completed NCT00453180 Phase 2 N-acetylcysteine;Placebo
11 Omega-3 Fatty Acids For Treatment Of Young Children With Autism (OMG) Completed NCT01248728 Phase 2
12 Safety Study of Memantine in Pediatric Patients With Autism, Asperger's Disorder or Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS) Terminated NCT01592773 Phase 2 Memantine Hydrochloride (HCl)
13 Brain Imaging Study of Adults With Autism Spectrum Disorders Completed NCT01093768 Phase 1 Oxytocin;Vasopressin
14 Placebo-Controlled Pilot Trial of Mecamylamine for Treatment of Autism Spectrum Disorders Completed NCT00773812 Phase 1 mecamylamine;placebo
15 Exposure-Focused Family-Based CBT for Youth With ASD and Comorbid Anxiety Completed NCT01919970
16 Cognitive Behavioral Therapy for Anxiety Disorders in Adolescents With Autism Completed NCT01563003
17 Predictors of Caregiver Adaptation to Pervasive Developmental Disorders Completed NCT00496210
18 Autism Spectrum Disorders (ASD) Characterization Study Completed NCT00801554
19 The Effects of a Clean Room Sleeping Environment on Elemental and Chemical Concentrations in Children With Autism Completed NCT02195401
20 Mitochondrial Dysfunction in Autism Spectrum Disorder Recruiting NCT02000284
21 Phenotypic and Genetic Factors in Autism Spectrum Disorders Active, not recruiting NCT00910559
22 Genetic Contributions to Autism Spectrum Disorders Active, not recruiting NCT01160783
23 The Association Between Herpes Simplex Viruses and Autism Not yet recruiting NCT03180112
24 Memantine in Adult Autism Spectrum Disorder Terminated NCT01078844 memantine;Placebo

Search NIH Clinical Center for Pervasive Developmental Disorder Not Otherwise Specified

Genetic Tests for Pervasive Developmental Disorder Not Otherwise Specified

Genetic tests related to Pervasive Developmental Disorder Not Otherwise Specified:

id Genetic test Affiliating Genes
1 Pervasive Developmental Disorder Not Otherwise Specified 24

Anatomical Context for Pervasive Developmental Disorder Not Otherwise Specified

MalaCards organs/tissues related to Pervasive Developmental Disorder Not Otherwise Specified:

39
Brain, Skin

Publications for Pervasive Developmental Disorder Not Otherwise Specified

Articles related to Pervasive Developmental Disorder Not Otherwise Specified:

(show all 45)
id Title Authors Year
1
The Stability of Comorbid Psychiatric Disorders: A 7A Year Follow Up of Children with Pervasive Developmental Disorder-Not Otherwise Specified. ( 26456972 )
2015
2
Detecting Subgroups in Children Diagnosed with Pervasive Developmental Disorder - Not Otherwise Specified. ( 25374133 )
2014
3
Fecal microbiota and metabolome of children with autism and pervasive developmental disorder not otherwise specified. ( 24130822 )
2013
4
Brief report: An unusual manifestation of diagnostic overshadowing of pervasive developmental disorder--not otherwise specified: a five year longitudinal case study. ( 23108987 )
2013
5
Yokukansan (TJ-54) for treatment of pervasive developmental disorder not otherwise specified and Asperger's disorder: a 12-week prospective, open-label study. ( 23194148 )
2012
6
Sexual obsessions, compulsions, suicidality and homicidality in an adolescent diagnosed with bipolar disorder not otherwise specified, obsessive-compulsive disorder, pervasive developmental disorder not otherwise specified, and mild mental retardation. ( 22612525 )
2012
7
Is long-term prognosis for pervasive developmental disorder not otherwise specified different from prognosis for autistic disorder? Findings from a 30-year follow-up study. ( 21713590 )
2012
8
Toward specifying pervasive developmental disorder-not otherwise specified. ( 21298812 )
2011
9
Analysis of Copper and Zinc Plasma Concentration and the Efficacy of Zinc Therapy in Individuals with Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS) and Autism. ( 22174567 )
2011
10
New onset of psychotic symptoms in an adolescent with pervasive developmental disorder, not otherwise specified. ( 21309699 )
2011
11
Is pervasive developmental disorder not otherwise specified less stable than autistic disorder? A meta-analysis. ( 21153874 )
2011
12
The relationship between race and challenging behaviours in infants and toddlers with autistic disorder and pervasive developmental disorder-not otherwise specified. ( 21732805 )
2011
13
Buspirone for bruxism in a child with pervasive developmental disorder-not otherwise specified. ( 22136097 )
2011
14
Epilepsy with continuous spikes and waves during slow wave sleep in a child diagnosed with pervasive developmental disorder-not otherwise specified. ( 20598941 )
2010
15
An open-label trial of topiramate in the treatment of skin picking in pervasive developmental disorder not otherwise specified. ( 20694122 )
2010
16
Communication deficits in babies and infants with autism and pervasive developmental disorder-not otherwise specified (PDD-NOS). ( 20887201 )
2010
17
Obsessional and atypical tic symptoms in an adolescent with complex Tourette's disorder and atypical pervasive developmental disorder not otherwise specified. ( 20578936 )
2010
18
Developmental milestones in toddlers with autistic disorder, pervasive developmental disorder--not otherwise specified and atypical development. ( 20629590 )
2010
19
A case study of a five-year-old child with pervasive developmental disorder-not otherwise specified using sound-based interventions. ( 19222056 )
2009
20
Social and communication behaviours in infants and toddlers with autism and pervasive developmental disorder-not otherwise specified. ( 19466623 )
2009
21
Aripiprazole in pervasive developmental disorder not otherwise specified and Asperger's disorder: a 14-week, prospective, open-label study. ( 19519261 )
2009
22
Social Skills Groups for Asperger's Disorder and Pervasive Developmental Disorder Not Otherwise Specified. ( 19727303 )
2008
23
Cognitive profile difference between normally intelligent children with Asperger's disorder and those with pervasive developmental disorder not otherwise specified. ( 19068006 )
2008
24
MRI-based morphometry in children with multiple complex developmental disorder, a phenotypically defined subtype of pervasive developmental disorder not otherwise specified. ( 17825125 )
2008
25
Successful olanzapine treatment of anorexia nervosa in a girl with pervasive developmental disorder not otherwise specified. ( 19068020 )
2008
26
Comparison of developmental/intellectual changes between autistic disorder and pervasive developmental disorder not otherwise specified in preschool years. ( 18081633 )
2007
27
Mood and anxiety symptoms in an adolescent with Pervasive Developmental Disorder Not Otherwise Specified and moderate mental retardation. ( 17979592 )
2007
28
Epilepsy in patients with pervasive developmental disorder not otherwise specified. ( 17940246 )
2007
29
Cognitive and symptom profiles in high-functioning pervasive developmental disorder not otherwise specified and attention-deficit/hyperactivity disorder. ( 16568358 )
2006
30
Differences in finger length ratio between males with autism, pervasive developmental disorder-not otherwise specified, ADHD, and anxiety disorders. ( 17109783 )
2006
31
Adaptive behavior in autism and Pervasive Developmental Disorder-Not Otherwise Specified: microanalysis of scores on the Vineland Adaptive Behavior Scales. ( 15162940 )
2004
32
Face recognition in children with a pervasive developmental disorder not otherwise specified. ( 12908833 )
2003
33
Prenatal, perinatal, and neonatal factors in autism, pervasive developmental disorder-not otherwise specified, and the general population. ( 11335784 )
2001
34
An assessment of food acceptance in children with autism or pervasive developmental disorder-not otherwise specified. ( 11794415 )
2001
35
How unspecified are disorders of children with a pervasive developmental disorder not otherwise specified? A study of social problems in children with PDD-NOS and ADHD. ( 11095039 )
2000
36
A comparison of social skills in adults with autistic disorder, pervasive developmental disorder not otherwise specified, and mental retardation. ( 10478728 )
1999
37
Exploring the boundaries of pervasive developmental disorder not otherwise specified: analyses of data from the DSM-IV Autistic Disorder Field Trial. ( 10097993 )
1999
38
Differentiating attention-deficit/hyperactivity disorder from pervasive developmental disorder not otherwise specified. ( 9813954 )
1998
39
Brief report: interpretation of facial expressions, postures and gestures in children with a pervasive developmental disorder not otherwise specified. ( 9656138 )
1998
40
Differential diagnosis between attention-deficit/hyperactivity disorder and pervasive developmental disorder--not otherwise specified. ( 9336673 )
1997
41
Pervasive developmental disorder, not otherwise specified: primary care perspectives. ( 9253013 )
1997
42
What is PDDNOS and how is it diagnosed? Pervasive Developmental Disorder Not Otherwise Specified. ( 9036148 )
1996
43
An exploration of person perception abilities in children with a pervasive developmental disorder not otherwise specified. ( 8608391 )
1995
44
Emotional role-taking abilities of children with a pervasive developmental disorder not otherwise specified. ( 7782410 )
1995
45
Differentiating pervasive developmental disorder not otherwise specified from autism and language disorders. ( 7681820 )
1993

Variations for Pervasive Developmental Disorder Not Otherwise Specified

Expression for Pervasive Developmental Disorder Not Otherwise Specified

Search GEO for disease gene expression data for Pervasive Developmental Disorder Not Otherwise Specified.

Pathways for Pervasive Developmental Disorder Not Otherwise Specified

GO Terms for Pervasive Developmental Disorder Not Otherwise Specified

Sources for Pervasive Developmental Disorder Not Otherwise Specified

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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