MCID: PTZ001
MIFTS: 68

Peutz-Jeghers Syndrome malady

Categories: Genetic diseases, Rare diseases, Eye diseases, Gastrointestinal diseases, Skin diseases, Fetal diseases, Cancer diseases

Aliases & Classifications for Peutz-Jeghers Syndrome

About this section
Sources:
49OMIM, 10Disease Ontology, 11diseasecard, 68Wikipedia, 21GeneReviews, 45NIH Rare Diseases, 22GeneTests, 23Genetics Home Reference, 47Novoseek, 12DISEASES, 51Orphanet, 67UniProtKB/Swiss-Prot, 36MeSH, 24GTR, 65UMLS, 27ICD10, 42NCIt, 59SNOMED-CT, 28ICD10 via Orphanet, 37MESH via Orphanet, 66UMLS via Orphanet, 34MedGen, 61The Human Phenotype Ontology
See all MalaCards sources

Aliases & Descriptions for Peutz-Jeghers Syndrome:

Name: Peutz-Jeghers Syndrome 49 10 11 68 21 45 22 23 47 12 51 67 36 24 65
Pjs 68 21 45 22 23 51 67
Polyps-and-Spots Syndrome 68 45 23 67
Polyposis, Hamartomatous Intestinal 68 45 23
Periorificial Lentiginosis Syndrome 68 45 23
Lentiginosis, Perioral 68 45 23
Intestinal Polyposis-Cutaneous Pigmentation Syndrome 68 23
Hamartomatous Intestinal Polyposis 22 51
Polyposis, Intestinal, Ii 68 23
Peutz-Jeghers Polyp of Small Intestine 10
Peutz-Jeghers Polyps of Small Bowel 65
Peutz-Jeghers Small Bowel Hamartoma 10
 
Intestinal Hamartomatous Polyposis 67
Peutz-Jeghers Polyp of the Stomach 65
Gastric Peutz-Jeghers Polyp 10
Colonic Hamartomatous Polyp 10
Polyps and Spots Syndrome 51
Peutz Jeghers Colon Polyp 10
Peutz-Jeghers Polyposis 23
Peutz Jeghers Polyposis 45
Hamartomatous Polyp 65
Peutz Jehgers Polyp 65
Peutz Jeghers Polyp 10

Characteristics:

Orphanet epidemiological data:

51
peutz-jeghers syndrome:
Inheritance: Autosomal dominant; Prevalence: 1-9/1000000 (Uruguay); Age of onset: Adolescent,Adult,Childhood; Age of death: adult

HPO:

61
peutz-jeghers syndrome:
Inheritance: autosomal dominant inheritance


Classifications:



External Ids:

OMIM49 175200
Disease Ontology10 DOID:3852
ICD1027 Q85.8
MeSH36 D010580
Orphanet51 2869
ICD10 via Orphanet28 Q85.8
MESH via Orphanet37 D010580
UMLS via Orphanet66 C0031269
MedGen34 C0031269
UMLS65 C0031269, C0265323, C0456487 C1333088, C1335398, C0334092, more

Summaries for Peutz-Jeghers Syndrome

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NIH Rare Diseases:45 Peutz-jeghers syndrome (pjs) is an inherited condition that is associated with an increased risk of growths along the lining of the gastrointestinal tract (called hamartomatous polyps) and certain types of cancer. most affected people also have characteristic dark blue to dark brown macules around the mouth, eyes, and nostrils; near the anus (perianal); and on the inside of the cheeks (buccal mucosa). pjs is caused by changes (mutations) in the stk11 gene and is inherited in an autosomal dominant manner. management typically includes high-risk screening for associated polyps and cancers. last updated: 3/15/2015

MalaCards based summary: Peutz-Jeghers Syndrome, also known as pjs, is related to suppurative thyroiditis and gliomatosis peritonei, and has symptoms including intestinal polyposis, lip hyperpigmentation and abnormal pigmentation of the oral mucosa. An important gene associated with Peutz-Jeghers Syndrome is STK11 (Serine/Threonine Kinase 11), and among its related pathways are FSH signaling pathway and Thyroid cancer. Affiliated tissues include colon, pancreas and breast, and related mouse phenotypes are pigmentation and limbs/digits/tail.

Genetics Home Reference:23 Peutz-Jeghers syndrome is characterized by the development of noncancerous growths called hamartomatous polyps in the gastrointestinal tract (particularly the stomach and intestines) and a greatly increased risk of developing certain types of cancer.

OMIM:49 Peutz-Jeghers syndrome is an autosomal dominant disorder characterized by melanocytic macules of the lips, buccal... (175200) more...

UniProtKB/Swiss-Prot:67 Peutz-Jeghers syndrome: An autosomal dominant disorder characterized by melanocytic macules of the lips, multiple gastrointestinal hamartomatous polyps and an increased risk for various neoplasms, including gastrointestinal cancer.

Wikipedia:68 Peutz-Jeghers syndrome, also known as hereditary intestinal polyposis syndrome, is an autosomal dominant... more...

GeneReviews summary for NBK1266

Related Diseases for Peutz-Jeghers Syndrome

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Graphical network of the top 20 diseases related to Peutz-Jeghers Syndrome:



Diseases related to peutz-jeghers syndrome

Symptoms for Peutz-Jeghers Syndrome

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Symptoms by clinical synopsis from OMIM:

175200

Clinical features from OMIM:

175200

Symptoms:

 51 (show all 34)
  • lip hyperpigmentation
  • abnormal pigmentation of the oral mucosa/gingivae
  • macules
  • pigmented naevi/naevus pigmentosus/lentigo
  • polyposis of the bowel/colon/intestine
  • neoplasms/tumors
  • digestive neoplasm/tumor/carcinoma/cancer
  • autosomal dominant inheritance
  • nasal polyposis
  • gynecomastia/breast/mammary gland enlargement/hyperplasia
  • abnormal nails colour/leukonychia/melanonychia
  • anus/rectum anomalies
  • nausea/vomiting/regurgitation/merycism/hyperemesis
  • acute abdominal pain/colic
  • gastrointestinal bleeding/hemorrhage/hematemesis/melena/rectorrhagia
  • intestinal obstruction/ileus
  • mesenteric/intestinal infarction
  • bladder and ureter anomalies
  • head and neck neoplasm/tumor/carcinoma/cancer
  • nose/nasal sinus neoplasm/tumor/carcinoma/cancer
  • esophageal neoplasm/tumor/carcinoma/cancer
  • estomach/gastric neoplasm/tumor/carcinoma/cancer
  • small bowel neoplasm/tumor/carcinoma/cancer
  • colon neoplasm/tumor/carcinoma/cancer
  • rectum/rectal neoplasm/tumor/carcinoma/cancer
  • pancreatic/pancreas neoplasm/tumor/carcinoma/cancer
  • extrahepatic biliary tract/gallbladder neoplasm/tumor/carcinoma/cancer
  • lung/bronchopulmonary neoplasm/tumor/carcinoma/cancer
  • breast neoplasm/tumor/carcinoma/cancer
  • uterus/uterine/cervix/endometrium neoplasm/tumor/carcinoma/cancer
  • ovary/fallopian tube neoplasm/tumor/carcinoma/cancer (excl. teratoma/germinoma)
  • testicular/seminal neoplasm/tumor/carcinoma/cancer (excl. teratoma/germinoma)
  • kidney/renal neoplasm/tumor/carcinoma/cancer
  • ureteral/urethral/vesical/bladder neoplasm/tumor/carcinoma/cancer

HPO human phenotypes related to Peutz-Jeghers Syndrome:

(show all 44)
id Description Frequency HPO Source Accession
1 intestinal polyposis hallmark (90%) HP:0200008
2 lip hyperpigmentation hallmark (90%) HP:0100816
3 abnormal pigmentation of the oral mucosa hallmark (90%) HP:0100669
4 hypermelanotic macule hallmark (90%) HP:0001034
5 melanocytic nevus hallmark (90%) HP:0000995
6 neoplasm of the small intestine occasional (7.5%) HP:0100833
7 esophageal neoplasm occasional (7.5%) HP:0100751
8 neoplasm of the rectum occasional (7.5%) HP:0100743
9 abnormality of nail color occasional (7.5%) HP:0100643
10 ovarian neoplasm occasional (7.5%) HP:0100615
11 nasal polyposis occasional (7.5%) HP:0100582
12 biliary tract neoplasm occasional (7.5%) HP:0100574
13 neoplasm of the lung occasional (7.5%) HP:0100526
14 neoplasm of the colon occasional (7.5%) HP:0100273
15 neoplasm of the breast occasional (7.5%) HP:0100013
16 testicular neoplasm occasional (7.5%) HP:0010788
17 uterine neoplasm occasional (7.5%) HP:0010784
18 renal neoplasm occasional (7.5%) HP:0009726
19 neoplasm of the stomach occasional (7.5%) HP:0006753
20 gastrointestinal infarctions occasional (7.5%) HP:0005244
21 intestinal obstruction occasional (7.5%) HP:0005214
22 neoplasm of the pancreas occasional (7.5%) HP:0002894
23 gastrointestinal hemorrhage occasional (7.5%) HP:0002239
24 abdominal pain occasional (7.5%) HP:0002027
25 nausea and vomiting occasional (7.5%) HP:0002017
26 gynecomastia occasional (7.5%) HP:0000771
27 clubbing of fingers HP:0100759
28 nasal polyposis HP:0100582
29 precocious puberty with sertoli cell tumor HP:0008204
30 hamartomatous polyposis HP:0004390
31 breast carcinoma HP:0003002
32 neoplasm of the pancreas HP:0002894
33 gastrointestinal carcinoma HP:0002672
34 intestinal bleeding HP:0002584
35 intussusception HP:0002576
36 rectal prolapse HP:0002035
37 abdominal pain HP:0002027
38 iron deficiency anemia HP:0001891
39 biliary tract abnormality HP:0001080
40 hypermelanotic macule HP:0001034
41 gynecomastia HP:0000771
42 abnormality of the mouth HP:0000153
43 ovarian cyst HP:0000138
44 abnormality of the ureter HP:0000069

Drugs & Therapeutics for Peutz-Jeghers Syndrome

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Drugs for Peutz-Jeghers Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 21)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
PancrelipaseapprovedPhase 1, Phase 288053608-75-6
Synonyms:
1,4-alpha-D- glucan glucanohydrolase
Creon
PA
Pancreatic alpha-amylase precursor
Pancreaze
 
Pancrelipase
Pertzye
Polocaine-mpf
Ultresa
Viokace
Zenpep
2
Secretinapproved, investigationalPhase 1, Phase 229108153-74-8
Synonyms:
108153-74-8
1393-25-5
67307-60-2 (citrate (salt))
9002-77-1
EINECS 215-733-3
Hormone of the duodenal mucosa that activates pancreatic secretion and lowers the blood sugar level
Human secretin
I06-1828
L-Histidyl-L-seryl-L-alpha-aspartylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-glutamyl-L-leucyl-L-seryl-L-arginyl-L-leucyl-L-arginyl-L-alpha-aspartyl-L-seryl-L-alanyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminylglycyl-L-leucyl-L-valinamide
L-Histidyl-L-seryl-L-alpha-aspartylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-glutamyl-L-leucyl-L-seryl-L-arginyl-L-leucyl-L-arginyl-L-alpha-glutamylglycyl-L-alanyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminylglycyl-L-leucyl-L-valinamide
LS-144747
RG 1068
SECREFLO
SECRETIN
SECRETIN-FERRING
 
SecreFlow
Secrepan
Secretin (human)
Secretin (porcine)
Secretin [INN:BAN:DCF:JAN]
Secretin-Kabi
Secretina
Secretina [INN-Spanish]
Secretine
Secretine [INN-French]
Secretinum
Secretinum [INN-Latin]
Secretolin
UNII-88C55N56UU
UNII-A0426J905J
Vitrum
3
Sirolimusapproved, investigationalPhase 2179753123-88-95284616, 6436030, 46835353
Synonyms:
(-)-Rapamycin
(-)-rapamycin
1fkb
1pbk
23,27-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine
23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine
23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29
3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
53123-88-9
A422989, NSC226080
AC-722
AC1L1JH9
AC1L7MJ9
AC1L9ZMV
AY 22989
AY-22989
AY22989
Ambotz53123-88-9
Antibiotic AY 22989
BIDD:PXR0165
Bio1_000293
Bio1_000782
Bio1_001271
Bio2_000375
Bio2_000855
BiomolKI2_000084
C07909
C51H79NO13
CBiol_002007
CCRIS 9024
CHEBI:100923
CHEBI:9168
CHEMBL413
CID10213190
CID10795871
CID11949238
CID11959112
CID313006
CID478951
CID5040
CID5284616
CID5358081
CID5374464
CID5460439
CID5497196
CID5924240
CID6436030
CID6610270
CID6610346
CID6711160
CID6713081
CID9833581
CID9854379
CID9854380
CID9962926
CID9962928
D00753
DB00877
DE-109
DivK1c_006936
 
FT-0082351
HMS2089A21
HSDB 7284
KBio1_001880
KBio2_000410
KBio2_002978
KBio2_005546
KBio3_000779
KBio3_000780
KBioGR_000410
KBioSS_000410
LCP-Siro
LMPK06000003
LS-143290
MLS000028373
MS-R001
MolMap_000043
MolPort-003-959-433
NCGC00021305-05
NCI60_001851
NCIMech_000355
NSC 226080
NSC226080
Perceiva
QTL1_000069
R0395_SIAL
R0395_SIGMA
RAP
RAPA
RPM
Rapammune
Rapamune
Rapamune (TN)
Rapamycin
Rapamycin (TN)
Rapamycin C-7, analog 4
Rapamycin Immunosuppressant Drug
Rapamycin from Streptomyces hygroscopicus
S1039_Selleck
SIIA 9268A
SILA 9268A
SILA9268A
SMP1_000255
SMR000058564
Sirolimus
Sirolimus (RAPAMUNE)
Sirolimus (USAN/INN)
Sirolimus [USAN:BAN:INN]
Sirolimus, Rapamune,Rapamycin
SpecPlus_000840
UNII-W36ZG6FT64
UNM-0000358684
WY-090217
Wy 090217
heptadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy
nchembio.100-comp4
nchembio.2007.42-comp2
nchembio.79-comp1
nchembio762-comp1
nchembio883-comp3
rapamycin
sirolimus
4
Miconazoleapproved, investigationalPhase 2302622916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
Desenex
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Makesense
Micantin (nitrate)
Micatin
 
Miconasil Nitrate
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Oravig
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
Rash Relief Antifungal
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
5
EverolimusapprovedPhase 21797159351-69-66442177
Synonyms:
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.04,9)hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,23S,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriacont
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34as)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethy
07741_FLUKA
159351-69-6
40-O-(2-hydroxyethyl)-rapamycin
42-O-(2-Hydroxyethyl)rapamycin
Afinitor
Afinitor Disperz
CERTICAN(R)
CHEMBL1201755
Certican
D02714
DB01590
 
Everolimus
Everolimus (JAN/USAN/INN)
Everolimus [USAN]
LS-143292
MolPort-003-847-342
MolPort-003-925-588
NCGC00167512-01
NVP-RAD-001
RAD 001
RAD-001
RAD-001C
RAD001
RAD001, SDZ-RAD, Certican, Zortress, Afinitor, Everolimus
S1120_Selleck
SDZ-RAD
UNII-9HW64Q8G6G
VOTUBIA
Zortress
everolimus
6pancreatinPhase 1, Phase 2880
7Gastrointestinal AgentsPhase 1, Phase 26401
8HormonesPhase 1, Phase 211748
9Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 1, Phase 29988
10Hormone AntagonistsPhase 1, Phase 210002
11Antifungal AgentsPhase 23015
12Anti-Bacterial AgentsPhase 29140
13Anti-Infective AgentsPhase 217220
14Antibiotics, AntitubercularPhase 25971
15Immunologic FactorsPhase 218483
16Immunosuppressive AgentsPhase 210422
17
Epinephrineapproved83451-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenaclick
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
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D00095
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Epinephran
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Epinephrine [USAN:INN:JAN]
Epinephrine bitartrate
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l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
18Mitogens1386
19Epinephryl borate834
20Racepinephrine834
21ColaNutraceutical1768

Interventional clinical trials:

(show all 16)
idNameStatusNCT IDPhase
1Pilot Study of mTOR Inhibitor Therapy in Peutz-Jeghers SyndromeTerminatedNCT00811590Phase 2
2Secretin (ChiRhoStim) Pancreas Perfusion for Pancreatic AdenocarcinomaTerminatedNCT00587132Phase 1, Phase 2
3Study of Everolimus in the Treatment of Advanced Malignancies in Patients With Peutz-Jeghers SyndromeWithdrawnNCT01178151Phase 2
4Cancer of the Pancreas Screening Study (CAPS 3)CompletedNCT00438906
5The Cancer of the Pancreas Screening-5 CAPS5)StudyRecruitingNCT02000089
6Pancreatic Cancer Early Detection ProgramRecruitingNCT02206360
7Hereditary Colorectal and Associated Tumor Registry StudyRecruitingNCT00633607
8Pancreas Registry and High Risk RegistryRecruitingNCT02775461
9Pancreatic Cancer Screening of High-Risk Individuals in ArkansasRecruitingNCT02309632
10Defining the Genetic Basis for the Development of Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the Carney ComplexRecruitingNCT00001452
11Genetics of EGFR (Epidermal Growth Factor Receptor) Mutation StudyRecruitingNCT01838577
12Prevalence of Small Bowel Polyps in Patients With Sporadic Duodenal AdenomasRecruitingNCT02470416
13Clinical, Genetic, Behavioral, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Breast/Ovarian CancerActive, not recruitingNCT00040222
14Screening for Early Pancreatic Neoplasia (Cancer of the Pancreas Screening or CAPS4 Study)Active, not recruitingNCT00714701
15Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the CARNEY Complex (CNC)Active, not recruitingNCT00668291
16International CAPS Registry: Pancreas Cancer Cases in Surveillance ProgramsEnrolling by invitationNCT02703545

Search NIH Clinical Center for Peutz-Jeghers Syndrome


Cochrane evidence based reviews: peutz-jeghers syndrome

Genetic Tests for Peutz-Jeghers Syndrome

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Genetic tests related to Peutz-Jeghers Syndrome:

id Genetic test Affiliating Genes
1 Peutz-Jeghers Syndrome22 STK11

Anatomical Context for Peutz-Jeghers Syndrome

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MalaCards organs/tissues related to Peutz-Jeghers Syndrome:

33
Colon, Pancreas, Breast, Eye, Small intestine, Lung, Kidney

Animal Models for Peutz-Jeghers Syndrome or affiliated genes

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MGI Mouse Phenotypes related to Peutz-Jeghers Syndrome:

38 (show all 29)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011869.0CTNNB1, CYP19A1, PRKAR1A, PTEN, TP53
2MP:00053718.7BRCA2, CTNNB1, PTEN, SMAD4, TP53
3MP:00053918.6CTNNB1, CYP19A1, PRKAR1A, PTEN, STK11, TP53
4MP:00053708.1CTNNB1, CYP19A1, INHA, PTEN, SMAD4, STK11
5MP:00053677.9CTNNB1, CYP19A1, PRKAA2, PTEN, SMAD4, STK11
6MP:00053757.9CYP19A1, MARK4, PRKAA2, PRKAR1A, PTEN, TP53
7MP:00107717.9BRCA2, CTNNB1, CYP19A1, PTEN, SMAD4, STK11
8MP:00053807.7BRCA2, CTNNB1, PRKAR1A, PTEN, SMAD4, STK11
9MP:00053697.7CTNNB1, CYP19A1, PRKAA2, PRKAR1A, PTEN, SMAD4
10MP:00053857.4CTNNB1, CYP19A1, INHA, PRKAR1A, PTEN, SMAD4
11MP:00036317.3BRCA2, CTNNB1, CYP19A1, PRKAA2, PTEN, SMAD4
12MP:00020067.3BRCA2, CTNNB1, INHA, PRKAR1A, PTEN, SMAD4
13MP:00053817.2BRCA2, CTNNB1, CYP19A1, INHA, PRKAR1A, PTEN
14MP:00053907.1BRCA2, CTNNB1, CYP19A1, INHA, PRKAR1A, PTEN
15MP:00107687.1BRCA2, CTNNB1, INHA, PRKAR1A, PTEN, SMAD4
16MP:00028737.0BRCA2, CTNNB1, CYP19A1, INHA, PRKAR1A, PTEN
17MP:00053877.0BRCA2, CTNNB1, CYP19A1, INHA, PRKAR1A, PTEN
18MP:00053896.9BRCA2, CTNNB1, CYP19A1, INHA, PRKAR1A, PTEN
19MP:00053846.8BRCA2, CTNNB1, CYP19A1, PRKAA2, PRKAR1A, PTEN
20MP:00053796.5BRCA2, CTNNB1, CYP19A1, INHA, PRKAA2, PRKAR1A
21MP:00053866.5BRCA2, CTNNB1, CYP19A1, MARK4, PRKAA2, PTEN
22MP:00053976.2BRCA2, CTNNB1, CYP19A1, INHA, PRKAA2, PRKAR1A
23MP:00053765.5BRCA2, CTNNB1, CYP19A1, INHA, MARK4, PRKAA2
24MP:00053785.5BRCA2, CTNNB1, CYP19A1, INHA, MARK4, PRKAA2

Publications for Peutz-Jeghers Syndrome

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Articles related to Peutz-Jeghers Syndrome:

(show top 50)    (show all 547)
idTitleAuthorsYear
1
Control of eight predominant Eimeria spp. involved in economic coccidiosis of broiler chicken by a chemically characterized essential oil. (25529022)
2015
2
Acute disseminated encephalomyelitis: the time until diagnosis and its subsequent course in children. (23143724)
2014
3
Molecular epidemiology of recurrent clinical mastitis due to Streptococcus uberis: Evidence of both an environmental source and recurring infection with the same strain. (24239086)
2014
4
Pulmonary Large Cell Carcinoma Lacking Squamous Differentiation Is Clinicopathologically Indistinguishable From Solid-Subtype Adenocarcinoma. (23738762)
2013
5
Hepatitis B vaccination coverage among health-care personnel in the United States. (24179261)
2013
6
CCL19/CCR7 upregulates heparanase via specificity protein-1 (Sp1) to promote invasion of cell in lung cancer. (23649655)
2013
7
Commentary on Petry eta88al. (2013): Actus Reus--why it matters to pathological gambling treatment. (23418660)
2013
8
Functional polymorphisms of folate metabolism and response to chemotherapy for colorectal cancer, a systematic review and meta-analysis. (22388795)
2012
9
Vitamin D receptor expression in patients with vulvar cancer. (22213317)
2012
10
Genome-wide association studies reveal genetic variants in CTNND2 for high myopia in Singapore Chinese. (21095009)
2011
11
Mammalian enabled (Mena) is a critical regulator of cardiac function. (21335464)
2011
12
Common variants in DGKK are strongly associated with risk of hypospadias. (21113153)
2011
13
A complex 6p25 rearrangement in a child with multiple epiphyseal dysplasia. (21204225)
2011
14
Three outbreaks of foodborne botulism caused by unsafe home canning of vegetables--Ohio and Washington, 2008 and 2009. (22186049)
2011
15
Tumor-initiating function of nucleostemin-enriched mammary tumor cells. (21045149)
2010
16
Hypoxic preconditioning suppresses group III secreted phospholipase A2-induced apoptosis via JAK2-STAT3 activation in cortical neurons. (20492356)
2010
17
Experimental study of implantation of neurotropin-3 modified olfactory ensheathing cells in experimental allergic encephalomyelitis]. (20017332)
2009
18
Association between genetic polymorphisms of DNA base excision repair genes and evolution of precancerous gastric lesions in a Chinese population. (19147860)
2009
19
SYBR Green-based real-time PCR assay for detection of VKORC1 and CYP2C9 polymorphisms that modulate warfarin dose requirement. (19117406)
2009
20
Changes in cytokine profile pre- and post-immunosuppression in acquired aplastic anemia. (19586939)
2009
21
Is exenatide improving the treatment of type 2 diabetes? Analysis of the individual clinical trials with exenatide. (18473991)
2007
22
Phorbol ester-induced shedding of the prostate cancer marker transmembrane protein with epidermal growth factor and two follistatin motifs 2 is mediated by the disintegrin and metalloproteinase-17. (17942404)
2007
23
Cytogenetic and PCR-based identification of S. damnosum "Nkusi J" as the anthropophilic blackfly in the Uluguru onchocerciasis focus in Tanzania. (16827707)
2006
24
Presentation of tumor antigens by dendritic cells genetically modified with viral and nonviral vectors. (17063124)
2006
25
Genetic aspects of age-related macular degeneration. (15947798)
2005
26
Cdk5 activator-binding protein C53 regulates apoptosis induced by genotoxic stress via modulating the G2/M DNA damage checkpoint. (15790566)
2005
27
Aseptic meningitis: diagnosis and management. (15684450)
2005
28
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is expressed in normal skin and cutaneous inflammatory diseases, but not in chronically UV-exposed skin and non-melanoma skin cancer. (15798435)
2005
29
Detection of BCL2-IGH rearrangement on paraffin-embedded tissue sections obtained from a small submucosal tumor of the rectum in a patient with recurrent follicular lymphoma. (15300917)
2004
30
Usefulness of 18FDG/13N-ammonia PET imaging for evaluation of the cardiac damage in Churg-Strauss syndrome. (15150672)
2004
31
Over-expression of the testis-specific gene TSGA10 in cancers and its immunogenicity. (15107545)
2004
32
Genetic background affects susceptibility in nonfatal pneumococcal bronchopneumonia. (14979496)
2004
33
Brain metastases in hepatoblastoma. (15087112)
2004
34
Pancreatic carcinoma cell lines with SMAD4 inactivation show distinct expression responses to TGFB1. (12619158)
2003
35
Arachnoiditis ossificans. (12650411)
2003
36
Alcohol and zymogen activation in the pancreatic acinar cell. (14576492)
2003
37
Regulation of cardiac adrenomedullin in heart failure. (11754971)
2001
38
Changes in insulin-like growth factor-binding protein-3 messenger ribonucleic acid in endothelial cells of the human corpus luteum: a possible role in luteal development and rescue. (10770214)
2000
39
Are antiphospholipid antibodies thrombogenic in the course of human immunodeficiency virus infection?]. (10192038)
1999
40
Glutathione S-transferase (GST) M1, T1, P1, N-acetyltransferase (NAT) 1 and 2 genetic polymorphisms and susceptibility to colorectal cancer. (10434361)
1999
41
Isolation and expression of a human SRY-related cDNA hSOX20. (9540826)
1998
42
Alcaptonuria in a Turkish baby. (9364134)
1997
43
Lecithin:cholesterol acyltransferase activity and high-density lipoprotein subfraction composition in type 1 diabetic patients with improving metabolic control. (8111077)
1993
44
Intervention at diagnosis of type I diabetes using either antioxidants or photopheresis. (7924831)
1993
45
Mammalian beta-D-mannosidase and beta-mannosidosis. (1576208)
1992
46
Leucocyte function in children with kwashiorkor. (1147655)
1975
47
A sign of intestinal perforation. (14476026)
1962
48
49
50

Variations for Peutz-Jeghers Syndrome

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UniProtKB/Swiss-Prot genetic disease variations for Peutz-Jeghers Syndrome:

67
id Symbol AA change Variation ID SNP ID
1STK11p.Leu67ProVAR_006202
2STK11p.Asp194AsnVAR_007921
3STK11p.Arg297LysVAR_007922
4STK11p.Trp239CysVAR_033142
5STK11p.Pro315SerVAR_033144
6STK11p.Glu16GlyVAR_065628
7STK11p.Asp176AsnVAR_071058
8STK11p.Trp308CysVAR_071059

Clinvar genetic disease variations for Peutz-Jeghers Syndrome:

5 (show all 28)
id Gene Variation Type Significance SNP ID Assembly Location
1STK11NM_000455.4(STK11): c.908T> G (p.Ile303Ser)single nucleotide variantLikely pathogenicrs727504171GRCh37Chr 19, 1221993: 1221993
2STK11NM_000455.4(STK11): c.921-2A> Tsingle nucleotide variantPathogenicrs727504172GRCh37Chr 19, 1222982: 1222982
3STK11NM_000455.4(STK11): c.988dupG (p.Asp330Glyfs)duplicationPathogenicrs786200991GRCh37Chr 19, 1223051: 1223051
4STK11NM_000455.4(STK11): c.580G> A (p.Asp194Asn)single nucleotide variantLikely pathogenicrs121913315GRCh38Chr 19, 1220488: 1220488
5STK11NM_000455.4(STK11): c.844dupC (p.Leu282Profs)duplicationPathogenicrs786205864GRCh37Chr 19, 1221321: 1221321
6STK11NM_000455.4(STK11): c.842delC (p.Pro281Argfs)deletionPathogenicrs121913321GRCh38Chr 19, 1221320: 1221320
7STK11NM_000455.4(STK11): c.863-1G> Asingle nucleotide variantLikely pathogenicrs863224448GRCh38Chr 19, 1221948: 1221948
8STK11NM_000455.4(STK11): c.719C> A (p.Ser240Ter)single nucleotide variantPathogenicrs730881976GRCh38Chr 19, 1220702: 1220702
9STK11NM_000455.4(STK11): c.923G> Tsingle nucleotide variantLikely pathogenicrs864622488GRCh38Chr 19, 1222987: 1222987
10STK11NM_000455.4(STK11): c.394delTdeletionPathogenicrs864622707GRCh38Chr 19, 1219343: 1219343
11STK11STK11, EX4-5DEL/EX6-7INVdeletionPathogenic
12STK11NM_000455.4(STK11): c.759C> A (p.Tyr253Ter)single nucleotide variantPathogenicrs137853075GRCh37Chr 19, 1221236: 1221236
13STK11NM_000455.4(STK11): c.843delG (p.Leu282Serfs)deletionPathogenicrs587776656GRCh38Chr 19, 1221321: 1221321
14STK11NM_000455.4(STK11): c.718_721delTCGG (p.Ser240Leufs)deletionPathogenicrs587776657GRCh38Chr 19, 1220701: 1220704
15STK11NM_000455.4(STK11): c.465-1G> Asingle nucleotide variantPathogenicrs587776658GRCh38Chr 19, 1220372: 1220372
16STK11NM_000455.4(STK11): c.250A> T (p.Lys84Ter)single nucleotide variantPathogenicrs137853076GRCh37Chr 19, 1207162: 1207162
17STK11NM_000455.4(STK11): c.834_835delTG (p.Cys278Trpfs)deletionPathogenicrs587776659GRCh38Chr 19, 1221312: 1221313
18STK11NM_000455.4(STK11): c.200T> C (p.Leu67Pro)single nucleotide variantPathogenicrs137853077GRCh37Chr 19, 1207112: 1207112
19STK11NM_000455.4(STK11): c.908_916delTCCGGCAGC (p.Ile303_His306delinsAsn)deletionPathogenicrs587776660GRCh38Chr 19, 1221994: 1222002
20STK11NM_000455.4(STK11): c.169G> T (p.Glu57Ter)single nucleotide variantPathogenicrs137854584GRCh37Chr 19, 1207081: 1207081
21STK11NM_000455.4(STK11): c.418delC (p.Leu140Trpfs)deletionPathogenicrs397518440GRCh37Chr 19, 1219366: 1219366
22STK11NM_000455.4(STK11): c.197dupT (p.Leu67Alafs)duplicationPathogenicrs397518441GRCh37Chr 19, 1207109: 1207109
23STK11NM_000455.4(STK11): c.717G> C (p.Trp239Cys)single nucleotide variantPathogenicrs137853082GRCh37Chr 19, 1220699: 1220699
24STK11NM_000455.4(STK11): c.891delG (p.Arg297Serfs)deletionPathogenicrs587776661GRCh37Chr 19, 1221976: 1221976
25STK11NM_000455.4(STK11): c.738C> G (p.Tyr246Ter)single nucleotide variantPathogenicrs137853083GRCh37Chr 19, 1221215: 1221215
26STK11NM_000455.4(STK11): c.169dupG (p.Glu57Glyfs)duplicationPathogenicrs398123404GRCh37Chr 19, 1207081: 1207081
27STK11NM_000455.4(STK11): c.877G> T (p.Glu293Ter)single nucleotide variantPathogenicrs398123405GRCh37Chr 19, 1221962: 1221962
28STK11NM_000455.4(STK11): c.921-1G> Tsingle nucleotide variantPathogenicrs398123406GRCh37Chr 19, 1222983: 1222983

Cosmic variations for Peutz-Jeghers Syndrome:

7
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Conf
1COSM18717APClarge intestine,colon,other,Peutz-Jeghers polyp1
2COSM18716APClarge intestine,colon,other,Peutz-Jeghers polyp1
3COSM18715APClarge intestine,colon,other,Peutz-Jeghers polyp1
4COSM520KRASlarge intestine,colon,other,Peutz-Jeghers polyp1

Expression for genes affiliated with Peutz-Jeghers Syndrome

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Search GEO for disease gene expression data for Peutz-Jeghers Syndrome.

Pathways for genes affiliated with Peutz-Jeghers Syndrome

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Pathways related to Peutz-Jeghers Syndrome according to GeneCards Suite gene sharing:

(show all 36)
idSuper pathwaysScoreTop Affiliating Genes
19.9CYP19A1, TSC2
29.6CTNNB1, TP53
3
Show member pathways
9.5CTNNB1, PTEN, TSC2
49.4CTNNB1, PTEN, SMAD4
59.4PRKAA2, PTEN, TSC2
69.4CTNNB1, PRKAA2, TSC2
7
Show member pathways
9.4PTEN, TP53, TSC2
89.4PTEN, TP53, TSC2
9
Show member pathways
9.4PTEN, TP53, TSC2
10
Show member pathways
9.4PTEN, TP53, TSC2
119.3CTNNB1, TP53, TSC2
129.3PTEN, SMAD4, TP53
139.2PRKAA2, PRKAR1A, STK11
14
Show member pathways
9.1PRKAA2, PTEN, SMAD4, STK11
159.0CTNNB1, PTEN, TP53, TSC2
168.9CTNNB1, SMAD4, STK11, TP53
17
Show member pathways
8.9PRKAA2, STK11, TP53, TSC2
18
Show member pathways
8.9PRKAA2, STK11, TP53, TSC2
19
Show member pathways
8.9PRKAA2, PRKAR1A, STK11, TSC2
20
Show member pathways
8.9BRCA2, SMAD4, TP53
21
Show member pathways
8.9BRCA2, SMAD4, TP53
228.9PRKAA2, PTEN, TP53, TSC2
238.7CTNNB1, PRKAR1A, SMAD4, TP53
24
Show member pathways
8.6PRKAA2, PTEN, STK11, TP53, TSC2
25
Show member pathways
8.6PRKAA2, PTEN, STK11, TP53, TSC2
268.6PRKAA2, PTEN, STK11, TP53, TSC2
27
Show member pathways
8.6PRKAA2, PRKAR1A, PTEN, STK11, TSC2
28
Show member pathways
8.6CTNNB1, PTEN, SMAD4, TP53, TSC2
29
Show member pathways
8.4BRCA2, CTNNB1, PTEN, TP53, TSC2
30
Show member pathways
8.3CTNNB1, PRKAA2, PTEN, STK11, TP53, TSC2
318.3BRCA2, CTNNB1, PTEN, SMAD4, TP53
328.2MARK4, SMAD4, STK11, TP53, TSC2
337.6BRCA2, CTNNB1, PRKAA2, PTEN, SMAD4, STK11
347.4BRCA2, CTNNB1, CYP19A1, PTEN, SMAD4, STK11
35
Show member pathways
7.4CTNNB1, PRKAA2, PRKAR1A, PTEN, SMAD4, STK11
36
Show member pathways
7.0BRCA2, CTNNB1, PRKAA2, PRKAR1A, PTEN, SMAD4

GO Terms for genes affiliated with Peutz-Jeghers Syndrome

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Biological processes related to Peutz-Jeghers Syndrome according to GeneCards Suite gene sharing:

(show all 21)
idNameGO IDScoreTop Affiliating Genes
1intrinsic apoptotic signaling pathway by p53 class mediatorGO:007233210.3STK11, TP53
2gastrulation with mouth forming secondGO:000170210.3CTNNB1, SMAD4
3positive regulation of autophagyGO:001050810.2PRKAA2, STK11
4negative regulation of TOR signalingGO:003200710.1PRKAA2, TSC2
5positive regulation of neuron apoptotic processGO:004352510.1CTNNB1, TP53
6SMAD protein signal transductionGO:006039510.0INHA, SMAD4
7cellular protein localizationGO:003461310.0CTNNB1, TP53
8canonical Wnt signaling pathwayGO:00600709.9CTNNB1, PTEN, STK11
9negative regulation of phosphatidylinositol 3-kinase signalingGO:00140679.8PTEN, TSC2
10positive regulation of histone H3-K4 methylationGO:00515719.7CTNNB1, SMAD4
11protein localizationGO:00081049.7TP53, TSC2
12DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediatorGO:00069789.7BRCA2, TP53
13cell agingGO:00075699.7BRCA2, TP53
14response to gamma radiationGO:00103329.6BRCA2, TP53
15intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorGO:00427719.6BRCA2, TP53
16energy reserve metabolic processGO:00061129.5PRKAA2, PRKAR1A, STK11
17negative regulation of cell growthGO:00303089.4SMAD4, STK11, TP53
18cell cycle arrestGO:00070509.3INHA, PRKAA2, TP53, TSC2
19regulation of cell cycleGO:00517269.2INHA, PTEN, TSC2
20cellular response to DNA damage stimulusGO:00069749.1BRCA2, STK11, TP53
21positive regulation of transcription, DNA-templatedGO:00458938.9BRCA2, CTNNB1, SMAD4, TP53

Molecular functions related to Peutz-Jeghers Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1gamma-tubulin bindingGO:00430159.0BRCA2, MARK4

Sources for Peutz-Jeghers Syndrome

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet