MCID: PYR026
MIFTS: 19

Peyronies Disease malady

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Summaries for Peyronies Disease

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33MalaCards
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MalaCards: Peyronies Disease is related to peyronie's disease and plantar fascial fibromatosis. An important gene associated with Peyronies Disease is IFNA2 (interferon, alpha 2), and among its related pathways are Toll-like receptor signaling pathway and Allograft rejection. The compounds toremifene and diethyl dithiocarbamate have been mentioned in the context of this disorder.

Aliases & Classifications for Peyronies Disease

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10DISEASES
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Aliases & Descriptions:

peyronies disease 10


Related Diseases for Peyronies Disease

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17GeneCards, 18GeneDecks
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Graphical network of diseases related to Peyronies Disease:



Diseases related to peyronies disease

Symptoms for Peyronies Disease

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Drugs & Therapeutics for Peyronies Disease

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

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Search NIH Clinical Center for Peyronies Disease

Genetic Tests for Peyronies Disease

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Anatomical Context for Peyronies Disease

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Animal Models for Peyronies Disease or affiliated genes

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Publications for Peyronies Disease

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52PubMed
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Articles related to Peyronies Disease:

idTitleAuthorsYear
1
Evidence that osteogenic progenitor cells in the human tunica albuginea may originate from stem cells: implications for peyronie disease. (16093362)
2005

Variations for Peyronies Disease

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Expression for genes affiliated with Peyronies Disease

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Peyronies Disease

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Pathways for genes affiliated with Peyronies Disease

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50PathCards, 30KEGG, 38NCBI BioSystems Database, 53QIAGEN, 55Reactome
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Pathways related to Peyronies Disease according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Toll-like receptor signaling pathway38
Regulation of toll-like receptor signaling pathway38
9.5IFNA2, TGFB1
2
Show member pathways
9.5IFNA2, TGFB1
39.5IFNA2, TGFB1
4
Show member pathways
9.0PDE5A, IFNA2, TGFB1

Compounds for genes affiliated with Peyronies Disease

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45Novoseek, 11DrugBank, 3BitterDB, 51PharmGKB, 29IUPHAR, 24HMDB, 61Tocris Bioscience
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Compounds related to Peyronies Disease according to GeneCards/GeneDecks:

(show all 27)
idCompoundScoreTop Affiliating Genes
1toremifene45 1110.9IFNA2, TGFB1
2diethyl dithiocarbamate459.9IFNA2, TGFB1
33-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide459.8IFNA2, TGFB1
4streptozotocin459.8IFNA2, TGFB1
5erythromycin45 3 51 1112.8IFNA2, TGFB1
6betacarotene459.8IFNA2, TGFB1
7rituximab45 51 1111.8TGFB1, IFNA2
8bleomycin45 1110.8IFNA2, TGFB1
9sildenafil29 45 51 24 1113.8PDE5A, TGFB1
10zidovudine45 51 1111.8TGFB1, IFNA2
11dipyridamole45 61 29 1112.8TGFB1, PDE5A
12polyethylene glycol459.8IFNA2, TGFB1
13vitamin-e459.8PDE5A, IFNA2
14theophylline45 29 24 1112.7PDE5A, TGFB1
15purine45 2410.7PDE5A, IFNA2
16gold459.7PDE5A, IFNA2
17sodium nitroprusside459.6PDE5A, TGFB1
18agarose459.6IFNA2, TGFB1
19thyroxine45 2410.6IFNA2, TGFB1
20etoposide45 51 61 1112.5TGFB1, IFNA2
21tamoxifen45 51 29 1112.5IFNA2, TGFB1
22ribonucleic acid459.4IFNA2, TGFB1
23indomethacin45 29 61 1112.4PDE5A, IFNA2, TGFB1
24histamine45 29 2411.3TGFB1, IFNA2, PDE5A
25vegf459.2TGFB1, IFNA2, PDE5A
2612-o-tetradecanoylphorbol 13-acetate459.2IFNA2, TGFB1
27estrogen459.1TGFB1, IFNA2, PDE5A

GO Terms for genes affiliated with Peyronies Disease

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16Gene Ontology
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Biological processes related to Peyronies Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1inflammatory responseGO:0069549.5IFNA2, TGFB1
2negative regulation of T cell proliferationGO:0421309.4PDE5A, TGFB1
3positive regulation of MAP kinase activityGO:0434069.3PDE5A, TGFB1
4blood coagulationGO:0075968.7PDE5A, IFNA2, TGFB1

Products for genes affiliated with Peyronies Disease

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Peyronies Disease

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet