MCID: PYR026
MIFTS: 19

Peyronies Disease malady

Summaries for Peyronies Disease

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34MalaCards
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MalaCards: Peyronies Disease is related to peyronie's disease and plantar fascial fibromatosis. An important gene associated with Peyronies Disease is IFNA2 (interferon, alpha 2), and among its related pathways are Toll-like receptor signaling pathway and Allograft rejection. The compounds toremifene and diethyl dithiocarbamate have been mentioned in the context of this disorder.

Aliases & Classifications for Peyronies Disease

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11DISEASES
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Aliases & Descriptions:

peyronies disease 11


Related Diseases for Peyronies Disease

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18GeneCards, 19GeneDecks
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Graphical network of diseases related to Peyronies Disease:



Diseases related to peyronies disease

Symptoms for Peyronies Disease

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Drugs & Therapeutics for Peyronies Disease

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search CenterWatch for Peyronies Disease

Genetic Tests for Peyronies Disease

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Anatomical Context for Peyronies Disease

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Animal Models for Peyronies Disease or affiliated genes

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Publications for Peyronies Disease

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53PubMed
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Articles related to Peyronies Disease:

idTitleAuthorsYear
1
Evidence that osteogenic progenitor cells in the human tunica albuginea may originate from stem cells: implications for peyronie disease. (16093362)
2005

Variations for Peyronies Disease

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Expression for genes affiliated with Peyronies Disease

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Peyronies Disease

Search GEO for disease gene expression data for Peyronies Disease.

Pathways for genes affiliated with Peyronies Disease

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51PathCards, 31KEGG, 39NCBI BioSystems Database, 54QIAGEN, 56Reactome
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Pathways related to Peyronies Disease according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Toll-like receptor signaling pathway39
Regulation of toll-like receptor signaling pathway39
9.5IFNA2, TGFB1
2
Show member pathways
9.5IFNA2, TGFB1
39.5IFNA2, TGFB1
4
Show member pathways
9.0PDE5A, IFNA2, TGFB1

Compounds for genes affiliated with Peyronies Disease

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46Novoseek, 12DrugBank, 3BitterDB, 52PharmGKB, 30IUPHAR, 25HMDB, 62Tocris Bioscience
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Compounds related to Peyronies Disease according to GeneCards/GeneDecks:

(show all 27)
idCompoundScoreTop Affiliating Genes
1toremifene46 1210.9IFNA2, TGFB1
2diethyl dithiocarbamate469.9IFNA2, TGFB1
33-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide469.8IFNA2, TGFB1
4streptozotocin469.8IFNA2, TGFB1
5erythromycin46 3 52 1212.8IFNA2, TGFB1
6betacarotene469.8IFNA2, TGFB1
7rituximab46 52 1211.8TGFB1, IFNA2
8bleomycin46 1210.8IFNA2, TGFB1
9sildenafil30 46 52 25 1213.8PDE5A, TGFB1
10zidovudine46 52 1211.8TGFB1, IFNA2
11dipyridamole46 62 30 1212.8TGFB1, PDE5A
12polyethylene glycol469.8IFNA2, TGFB1
13vitamin-e469.8PDE5A, IFNA2
14theophylline46 30 25 1212.7PDE5A, TGFB1
15purine46 2510.7PDE5A, IFNA2
16gold469.7PDE5A, IFNA2
17sodium nitroprusside469.6PDE5A, TGFB1
18agarose469.6IFNA2, TGFB1
19thyroxine46 2510.6IFNA2, TGFB1
20etoposide46 52 62 1212.5TGFB1, IFNA2
21tamoxifen46 52 30 1212.5IFNA2, TGFB1
22ribonucleic acid469.4IFNA2, TGFB1
23indomethacin46 30 62 1212.4PDE5A, IFNA2, TGFB1
24histamine46 30 2511.3TGFB1, IFNA2, PDE5A
25vegf469.2TGFB1, IFNA2, PDE5A
2612-o-tetradecanoylphorbol 13-acetate469.2IFNA2, TGFB1
27estrogen469.1TGFB1, IFNA2, PDE5A

GO Terms for genes affiliated with Peyronies Disease

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17Gene Ontology
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Biological processes related to Peyronies Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1inflammatory responseGO:0069549.5IFNA2, TGFB1
2negative regulation of T cell proliferationGO:0421309.4PDE5A, TGFB1
3positive regulation of MAP kinase activityGO:0434069.3PDE5A, TGFB1
4blood coagulationGO:0075968.7PDE5A, IFNA2, TGFB1

Products for genes affiliated with Peyronies Disease

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Peyronies Disease

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet