MCID: PHC003
MIFTS: 81

Pheochromocytoma malady

Endocrine diseases, Cancer diseases categories

Summaries for Pheochromocytoma

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42NIH Rare Diseases, 33MedlinePlus, 63Wikipedia, 46OMIM, 32MalaCards
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MedlinePlus:33 Pheochromocytoma is a rare tumor that usually starts in the cells of one of your adrenal glands. although they are usually benign, pheochromocytomas often cause the adrenal gland to make too many hormones. this can lead to high blood pressure and cause symptoms such as headaches sweating pounding of the heart being shaky being extremely pale sometimes pheochromocytoma is part of another condition called multiple endocrine neoplasia syndrome (men). people with men often have other cancers and other problems involving hormones. doctors use lab tests and imaging tests to diagnose it. surgery is the most common treatment. other options include radiation therapy, chemotherapy, and targeted therapy. targeted therapy uses substances that attack cancer cells without harming normal cells. nih: national cancer institute

MalaCards: Pheochromocytoma, also known as bilateral pheochromocytoma and islet cell adenoma of the pancreas, is related to paraganglioma and von hippel-lindau disease. An important gene associated with Pheochromocytoma is SDHB (succinate dehydrogenase complex, subunit B, iron sulfur (Ip)), and among its related pathways are Metabolism and Pyruvate metabolism. The drugs propranolol and propranolol hydrochloride and the compounds vegf and tyrosine have been mentioned in the context of this disorder. Affiliated tissues include adrenal gland, testes and thyroid, and related mouse phenotypes are mortality/aging and cardiovascular system.

NIH Rare Diseases:42 Pheochromocytomas are rare tumors of the adrenal glands, which are located right above the kidneys. although they are usually not cancerous (benign), pheochromocytomas often cause the adrenal glands to make too many stress hormones called epinephrines and norepinephrines. this can lead to high blood pressure and cause symptoms such as severe headaches, irritability, sweating, rapid heart rate, nausea, vomiting, weight loss, weakness, chest pain, and a feeling of anxiety. rarely, this kind of tumor occurs outside the adrenal gland, usually somewhere in the abdomen, and are called extra-adrenal pheochromocytomas or paragangliomas. pheochromocytomas can occur in certain familial genetic syndromes. last updated: 4/27/2011

Wikipedia:63 A pheochromocytoma (from Greek phaios \"dark\", chroma \"color\", kytos \"cell\", -oma \"tumor\") or... more...

Description from OMIM:46 171300

Aliases & Classifications for Pheochromocytoma

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63Wikipedia, 42NIH Rare Diseases, 22GTR, 46OMIM, 44Novoseek, 33MedlinePlus, 60UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Endocrine diseases


Aliases & Descriptions:

pheochromocytoma 63 42 22 46 44 33 60
bilateral pheochromocytoma and islet cell adenoma of the pancreas 60
chromaffin paraganglioma 42
medullary paraganglioma 42
chromaffin cell tumor 42
chromaffin tumor 42
chromaffinoma 42


Related Diseases for Pheochromocytoma

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17GeneCards, 18GeneDecks
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Diseases in the Pheochromocytoma family:

Tmem127-Related Susceptibility to Pheochromocytoma Ret-Related Pheochromocytoma
Kif1b-Related Pheochromocytoma Vhl-Related Pheochromocytoma
Max-Related Susceptibility to Pheochromocytoma

Diseases related to Pheochromocytoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 247)
idRelated DiseaseScoreTop Affiliating Genes
1paraganglioma31.3SDHA, SDHC, SDHB, SDHD, PNMT, TH
2von hippel-lindau disease30.9SDHC, VHL, RET, SDHB, SDHD, TMEM127
3hypertension30.8TH, PNMT, ADM
4hereditary paraganglioma-pheochromocytoma syndromes30.8SDHC, SDHB, SDHD
5ganglioneuroma30.8NGF, RET, CHGA, TH
6neurofibromatosis30.7SDHC, SDHD, VHL, RET, SDHB
7thyroid medullary carcinoma30.7CHGA, RET, GDNF, VHL, SST, CHGB
8adenoma30.7CHGA, CHGB, SST, GDNF, RET, VHL
9neuroblastoma30.6NGF, TH
10adrenal adenoma30.5SDHC, ADM, CHGA, VHL, SDHB, SDHD
11cushing's syndrome30.5CHGA, RET, SST
12hyperparathyroidism30.4RET, CHGA, SDHD, SDHB, SDHC
13ganglioneuroblastoma30.3TH
14pancreatitis30.3SST
15thyroid cancer30.2RET, SST, CHGA
16familial medullary thyroid carcinoma30.2GDNF, RET
17adenocarcinoma30.2SST, CHGB, CHGA, VHL, ADM
18neuroendocrine tumor30.2CHGA, SST
19pituitary adenoma30.1CHGA, CHGB, SST, GDNF, RET, ADM
20gastrointestinal stromal tumor30.1SDHA, SDHC, SDHB
21diarrhea30.1SST, CHGA
22multiple endocrine neoplasia type 2a30.0SDHC, SDHB, RET, SDHD, VHL, GDNF
23neuroma30.0RET, GDNF
24parathyroid adenoma30.0CHGB, RET, CHGA
25phaeochromocytoma29.9SDHC, CHGA, NGF, RET, ADM, SDHD
26hemangioma29.9SDHC, SDHB, VHL, RET, SDHD
27neuropathy29.9NGF
28breast cancer29.7VHL, TH, ADM, SDHB, SDHC
29hyperthyroidism29.7SST, SDHB, SDHA, ADM
30ischemia29.7SDHB, GDNF, TH, ADM
31carney triad29.7SDHB, SDHC, SDHD
32paraganglioma and gastric stromal sarcoma29.7SDHD, SDHB, SDHC
33lung small cell carcinoma29.7SST, GDNF, CHGA, VHL
34parkinson's disease29.7PNMT, TH, GDNF, NGF
35leukemia29.7GDNF, NGF
36somatostatinoma29.7SST, CHGA
37addison's disease29.7TH
38merkel cell carcinoma29.7CHGA
39zollinger-ellison syndrome29.7SST, CHGA
40diabetic neuropathy29.6NGF, GDNF
41thyroiditis10.6
42neuronitis10.4
43adrenal carcinoma10.3
44hemangioblastoma10.2
45primary hyperparathyroidism10.2
46malignant hypertension10.2
47neurofibromatosis-pheochromocytoma-duodenal carcinoid syndrome10.2
48hyperaldosteronism10.2
49papillary carcinoma10.1
50papillary thyroid carcinoma10.1

Graphical network of the top 20 diseases related to Pheochromocytoma:



Diseases related to pheochromocytoma

Clinical Features for Pheochromocytoma

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46OMIM
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Clinical features from OMIM:

171300

Clinical synopsis from OMIM:

171300

Drugs & Therapeutics for Pheochromocytoma

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Pheochromocytoma

Drug clinical trials:

Search ClinicalTrials for Pheochromocytoma

Search NIH Clinical Center for Pheochromocytoma

Search CenterWatch for Pheochromocytoma

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Pheochromocytoma

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22GTR
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Genetic tests related to Pheochromocytoma:

id Genetic test Affiliating Genes
1 Pheochromocytoma22

Anatomical Context for Pheochromocytoma

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32MalaCards
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MalaCards organs/tissues related to Pheochromocytoma:

32
Adrenal gland, Testes, Thyroid, Heart, Pancreas, Kidney, Pituitary, Endothelial, Bone, Liver, Brain, Pancreatic islet, Lung, Adipocyte, Adrenal cortex, B cells, Prostate, Skin, Breast, Cortex, Retina, Colon, Eye

Animal Models for Pheochromocytoma or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Pheochromocytoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:001076811.8GDNF, NGF, MAX, CHGA, VHL, RET
2MP:000538511.8SDHD, VHL, CHGA, NGF, GDNF, RET
3MP:000537611.6VHL, CHGA, CHGB, SST, NGF, RET
4MP:000536911.5VHL, IFRD1, NGF, GDNF, RET, KIF1B
5MP:000537811.5SST, CHGA, IFRD1, VHL, MAX, NGF
6MP:000287311.2SST, NGF, RET, TH, PNMT, SDHD
7MP:000363111.1CHGB, SST, NGF, GDNF, RET, KIF1B
8MP:000537910.7CHGB, GDNF, RET

Publications for Pheochromocytoma

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50PubMed
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Articles related to Pheochromocytoma:

(show top 50)    (show all 1225)
idTitleAuthorsYear
1
Childhood pheochromocytoma in a survivor of central primitive neuroectodermal tumor. (23910809)
2013
2
Can hybrid SPECT-CT overcome the limitations associated with poor imaging properties of 131I-MIBG?: Comparison with planar scintigraphy and SPECT in pheochromocytoma. (23510889)
2013
3
Fibroblast growth factor-21 is expressed in neonatal and pheochromocytoma-induced adult human brown adipose tissue. (24369918)
2013
4
Bedside to bench: role of muscarinic receptor activation in ultrarapid growth of colorectal cancer in a patient with pheochromocytoma. (24100192)
2013
5
Is the excess cardiovascular morbidity in pheochromocytoma related to blood pressure or to catecholamines? (23408574)
2013
6
White-to-brown transdifferentiation of omental adipocytes in patients affected by pheochromocytoma. (23454374)
2013
7
Acute myocardial infarction secondary to catecholamine release owing to cocaine abuse and pheochromocytoma crisis. (23853620)
2013
8
Tianeptine interferes with microtubule organization and hormone secretion of pheochromocytoma cells. (23933152)
2013
9
Multimodality molecular imaging in the evaluation of pheochromocytoma. A case report. (22762989)
2013
10
Recurrent left ventricular apical ballooning syndrome in a patient with pheochromocytoma. (23449065)
2012
11
NF-I_B inhibition significantly upregulates the norepinephrine transporter system, causes apoptosis in pheochromocytoma cell lines and prevents metastasis in an animal model. (22407736)
2012
12
Mutation screening of RET proto-oncogene in a family with medullary thyroid carcinoma, marfanoid habitus and pheochromocytoma; from clinically MEN2B to genetically MEN2A syndrome. (22290487)
2012
13
Hypertensive retinopathy in a child caused by pheochromocytoma: identification after a failed school vision screening. (22245022)
2012
14
Pheochromocytoma: a rare cause of childhood hypertensive encephalopathy. (22868025)
2012
15
Somatic mutation analysis of the SDHB, SDHC, SDHD, and RET genes in the clinical assessment of sporadic and hereditary pheochromocytoma. (22573489)
2012
16
Pheochromocytoma of the adrenal gland selectively secreting dopamine -- a case report. (23115074)
2012
17
Contrast- and non-contrast-enhanced ultrasonography (US) findings of hepatic metastasis from malignant pheochromocytoma/paraganglioma. (22271156)
2012
18
Tako-tsubo cardiomyopathy precipitated by pheochromocytoma crisis. (21947995)
2011
19
Minimally invasive treatment of metastatic pheochromocytoma and paraganglioma: efficacy and safety of radiofrequency ablation and cryoablation therapy. (21856504)
2011
20
Use of the tyrosine kinase inhibitor sunitinib in a patient with von Hippel-Lindau disease: targeting angiogenic factors in pheochromocytoma and other von Hippel-Lindau disease-related tumors. (19017755)
2009
21
False-positive 123I-metaiodobenzylguanidine (MIBG) scan in a patient with angiomyolipoma; positive MIBG scan does not necessarily indicate the presence of pheochromocytoma. (17938527)
2007
22
Use of 2-tracer PET to diagnose gastrointestinal stromal tumour and pheochromocytoma in patients with Carney triad and neurofibromatosis type 1. (16638708)
2006
23
Topographic molecular profile of pheochromocytomas: role of somatic down-regulation of mismatch repair. (16394087)
2006
24
GDNF-induced leukemia inhibitory factor can mediate differentiation via the MEK/ERK pathway in pheochromocytoma cells derived from nf1-heterozygous knockout mice. (15572029)
2005
25
Adrenomedullin: a smart road from pheochromocytoma to treatment of pulmonary hypertension. (15459126)
2004
26
Expression of vascular endothelial growth factor (VEGF) and its cognate receptors in human pheochromocytomas. (14659975)
2004
27
Potential mechanisms responsible for chlorotriazine-induced alterations in catecholamines in pheochromocytoma (PC12) cells. (14550852)
2003
28
Dynamic change of neural cell adhesion molecule polysialylation on human neuroblastoma (IMR-32) and rat pheochromocytoma (PC-12) cells during growth and differentiation. (12023285)
2002
29
Pheochromocytoma and multifocal functioning paraganglioma in a 9-year-old boy with von Hippel-Lindau disease. (12053037)
2002
30
Congenital hemihypertrophy and pheochromocytoma, not a coincidental combination? (11998914)
2002
31
Toluene inhibits voltage-sensitive calcium channels expressed in pheochromocytoma cells. (12213226)
2002
32
Human pheochromocytomas express orexin receptor type 2 gene and display an in vitro secretory response to orexins A and B. (11600547)
2001
33
Enhanced expression of mRNA coding for the adrenaline-synthesizing enzyme phenylethanolamine-N-methyl transferase in adrenaline-secreting pheochromocytomas. (10604389)
2000
34
Results of surgery for a compound adrenal tumor consisting of pheochromocytoma and ganglioneuroblastoma in an adult: 5-year follow-up. (10674851)
2000
35
Maxillary giant cell granuloma, pheochromocytoma, and hyperparathyroidism without medullary thyroid carcinoma. (10969467)
2000
36
Malignant pheochromocytoma with progressive paraparesis in von Hippel-Lindau disease. (10971605)
2000
37
Dynamic left ventricular outflow tract obstruction in a patient with pheochromocytoma. (10737567)
1999
38
Rat alpha(2)-macroglobulin inhibits NGF-promoted neurite outgrowth, TrK phosphorylation, and gene expression of pheochromocytoma PC12 cells. (10467259)
1999
39
Noncardiogenic pulmonary edema as the chief manifestation of a pheochromocytoma: a case report of MEN 2A with pedigree analysis of the RET proto-oncogene. (10526879)
1999
40
Nerve growth factor stimulates diacylglycerol de novo synthesis and phosphatidylinositol hydrolysis in pheochromocytoma cells. (9729268)
1998
41
Signal transduction pathways activated by RET oncoproteins in PC12 pheochromocytoma cells. (9478934)
1998
42
Growth factors differentially stimulate the phosphorylation of Shc proteins and their association with Grb2 in PC-12 pheochromocytoma cells. (8288573)
1994
43
Angiotensin-II mediates norepinephrine and neuropeptide-Y secretion in a human pheochromocytoma. (7989494)
1994
44
Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells. (2156866)
1990
45
Neuropeptide Y and neuron-specific enolase levels in benign and malignant pheochromocytomas. (2208039)
1990
46
Adrenal pheochromocytoma PC12h cells respond to pituitary adenylate cyclase activating polypeptide. (2175177)
1990
47
Concomitant occurrence of an adrenal ganglioneuroma and a contralateral pheochromocytoma in a patient with von Recklinghausen's neurofibromatosis. An immunocytochemical study. (2491953)
1989
48
Malignant pheochromocytoma with ganglioneuroblastoma elements in a patient with von Recklinghausen's disease. (3922614)
1985
49
Clinical significance of the association of the Von Hippel-Lindau disease with pheochromocytoma and pancreatic apudoma. (6517090)
1984
50
Coexistence of pheochromocytoma, adrenal adenoma and hypokalemia. (844017)
1977

Genetic Variations for Pheochromocytoma

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62UniProtKB/Swiss-Prot
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Genetic disease variations for Pheochromocytoma:

62 (show all 45)
id Symbol AA change Variation ID SNP ID
1RETp.Cys634GlyVAR_006323
2RETp.Cys634PheVAR_006324
3RETp.Cys634TyrVAR_006325
4RETp.Cys634ArgVAR_006326
5RETp.Cys634SerVAR_006327
6RETp.Cys634TrpVAR_006328
7RETp.Tyr791PheVAR_009483rs77724903
8SDHBp.Arg242HisVAR_017869
9SDHBp.Leu87SerVAR_018517
10SDHBp.Arg46GlyVAR_035064
11SDHBp.Cys101TyrVAR_035065
12SDHBp.Cys192ArgVAR_035066
13SDHBp.Cys196TyrVAR_035067
14SDHBp.Ser100PheVAR_037620
15SDHBp.Ala43ProVAR_054376
16SDHBp.Arg46GlnVAR_054377
17SDHBp.Gly53ArgVAR_054378
18SDHBp.Leu65HisVAR_054379
19SDHBp.Leu65ProVAR_054380
20SDHBp.Ile127AsnVAR_054381
21SDHBp.Arg230CysVAR_054383rs138996609
22SDHDp.Pro81LeuVAR_010038
23SDHDp.Asp92TyrVAR_010039
24VHLp.Ser68TrpVAR_005675
25VHLp.Ser80AsnVAR_005688rs5030805
26VHLp.Gly93CysVAR_005703rs5030808
27VHLp.Gly93SerVAR_005705rs5030808
28VHLp.Tyr98HisVAR_005707rs5030809
29VHLp.Phe119LeuVAR_005728
30VHLp.Phe136CysVAR_005737rs5030833
31VHLp.Tyr156CysVAR_005743
32VHLp.Arg161GlnVAR_005751
33VHLp.Arg161ProVAR_005752
34VHLp.Arg167GlnVAR_005761rs5030821
35VHLp.Arg167TrpVAR_005762rs5030820
36VHLp.Leu188ValVAR_005777rs5030824
37VHLp.Pro25LeuVAR_034562rs35460768
38VHLp.Leu63ProVAR_034987
39VHLp.Arg64ProVAR_034988
40VHLp.Ser65AlaVAR_034989
41VHLp.Arg107GlyVAR_034991
42VHLp.Ala122IleVAR_034993
43VHLp.Ile147ThrVAR_034996
44VHLp.Tyr156AsnVAR_034997
45VHLp.Leu198GlnVAR_035001

Expression for genes affiliated with Pheochromocytoma

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Pheochromocytoma

Search GEO for disease gene expression data for Pheochromocytoma.

Pathways for genes affiliated with Pheochromocytoma

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53Reactome, 29KEGG, 12EMD Millipore, 37NCBI BioSystems Database, 4Cell Signaling Technology
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Compounds for genes affiliated with Pheochromocytoma

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44Novoseek, 11DrugBank, 24HMDB, 49PharmGKB, 28IUPHAR, 59Tocris Bioscience
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Compounds related to Pheochromocytoma according to GeneCards/GeneDecks:

(show top 50)    (show all 73)
idCompoundScoreTop Affiliating Genes
1vegf4411.9CHGA, NGF, GDNF, RET, SST, TH
2tyrosine4411.9VHL, CHGA, TH, RET, GDNF, PNMT
3catecholamine4411.8PNMT, CHGA, SDHB, SDHD, CHGB, GDNF
4norepinephrine44 11 2413.8ADM, GDNF, SDHB, PNMT, NGF, SST
5oxygen44 2412.8VHL, SDHA, SDHC, SDHB, SDHD, ADM
6retinoic acid44 2412.6NGF, GDNF, RET, CHGA, TH, ADM
7epinephrine44 11 2413.6CHGA, NGF, PNMT, ADM, SDHB, SST
8acetylcholine44 49 28 11 2415.6CHGA, SST, TH, NGF, ADM, PNMT
9iron44 2412.6SDHA, TH, VHL, SDHD, SDHC, SDHB
10adenylate4411.6TH, RAMP2, GDNF, NGF, CHGA, SST
11testosterone44 59 11 2414.5RET, SDHB, ADM, TH, NGF, SST
12mibg4411.5TH, SDHB, SDHD, ADM, CHGA, SST
13succinate4411.5SDHC, SDHA, VHL, RET, SDHD, SDHB
14dopamine44 28 11 2414.5PNMT, GDNF, CHGB, TH, CHGA, SDHB
15levodopa44 1112.5PNMT, GDNF, SST, CHGA, NGF, TH
16histamine44 28 2413.5NGF, CHGA, TH, ADM, SST, PNMT
17cysteine4411.5GDNF, NGF, TH, SDHB, ADM, RET
18glucose4411.4VHL, SDHB, ADM, UTS2R, CHGA, GDNF
19dexamethasone44 49 28 1114.4RAMP2, PNMT, TH, CHGB, GDNF
20cyclic amp44 2412.4RET, ADM, NGF, GDNF, CHGA, TH
21carbachol44 28 1113.4NGF, ADM, TH, SST, CHGA
22choline44 11 2413.4SST, GDNF, RET, TH, NGF
23nicotine44 49 28 1114.3VHL, CHGA, NGF, TH, PNMT
24UBIQUINONE-11111.3SDHA, SDHD, SDHC, SDHB
252-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol1111.3SDHD, SDHA, SDHC, SDHB
26fumarate44 1112.3SDHC, SDHB, SDHD, VHL
27oligonucleotide4411.3VHL, CHGB, CHGA, ADM, RET, GDNF
28iron-sulfur4411.3SDHC, SDHB, SDHA, SDHD
29succinic acid28 11 2413.3SDHA, SDHC, SDHB, SDHD
30l-amino acid4411.3PNMT, TH, GDNF, CHGA
31ubiquinone4411.3SDHA, SDHD, SDHB, SDHC
32ly2940024411.3GDNF, NGF, VHL, RET, TH
33mptp4411.2NGF, GDNF, TH, SST
34forskolin44 49 1113.2GDNF, ADM, TH, MAX
35actinomycin d4411.2GDNF, NGF, VHL, TH, ADM
36propranolol44 28 49 11 2415.2NGF, ADM, SST, CHGA
37arginine4411.1SST, NGF, RET, ADM, SDHB, CHGA
385-hydroxytryptamine4411.1TH, PNMT, CHGA, SST
39peptidylglycine4411.1CHGB, ADM, CHGA
405-hydroxytryptophan4411.1TH, SST, CHGA
41selegiline44 1112.1NGF, GDNF, TH
42acth4411.0ADM, CHGB, CHGA, SST
43cipa4411.0NGF, RET
44streptozotocin4411.0SST, ADM, CHGA
456-hydroxydopamine4411.0TH, GDNF, NGF
46amphetamine44 1111.9TH, GDNF, SST
47lactate4410.9CHGA, SST, SDHB, TH, ADM
48normetanephrine44 2411.7PNMT, CHGA
49gnrh4410.7TH, CHGA
50clonidine44 28 1112.5CHGA, PNMT, SST

GO Terms for genes affiliated with Pheochromocytoma

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16Gene Ontology
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Cellular components related to Pheochromocytoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1mitochondrionGO:00573910.9VHL, KIF1B, TH, SDHD, SDHB, SDHC
2mitochondrial inner membraneGO:00574310.9SDHA, SDHC, SDHB, SDHD
3mitochondrial respiratory chain complex IIGO:00574910.8SDHA, SDHC, SDHB, SDHD

Biological processes related to Pheochromocytoma according to GeneCards/GeneDecks:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1tricarboxylic acid cycleGO:00609911.2SDHA, SDHC, SDHB, SDHD
2respiratory electron transport chainGO:02290411.1SDHA, SDHC, SDHB, SDHD
3cellular metabolic processGO:04423711.1SDHA, SDHC, SDHB, SDHD
4epinephrine biosynthetic processGO:04241810.9TH, PNMT
5vascular smooth muscle cell developmentGO:09708410.9ADM, RAMP2
6catecholamine biosynthetic processGO:04242310.9TH, PNMT
7succinate metabolic processGO:00610510.8SDHA, SDHB
8positive regulation of vasculogenesisGO:200121410.8ADM, RAMP2
9response to lipopolysaccharideGO:03249610.8ADM, TH, NGF
10negative regulation of vascular permeabilityGO:04311610.7RAMP2, ADM
11cAMP biosynthetic processGO:00617110.7RAMP2, ADM
12positive regulation of angiogenesisGO:04576610.7RAMP2, UTS2R, ADM
13response to electrical stimulusGO:05160210.4TH, NGF

Molecular functions related to Pheochromocytoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:00517910.8ADM, SST, CHGB
2succinate dehydrogenase (ubiquinone) activityGO:00817710.6SDHA, SDHB
3ubiquinone bindingGO:04803910.4SDHB, SDHD

Products for genes affiliated with Pheochromocytoma

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  • Antibodies
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Sources for Pheochromocytoma

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet