MCID: PHC003
MIFTS: 81

Pheochromocytoma malady

Endocrine diseases, Cancer diseases categories

Summaries for Pheochromocytoma

About this section
Sources:
42NIH Rare Diseases, 33MedlinePlus, 63Wikipedia, 46OMIM, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
MedlinePlus:33 Pheochromocytoma is a rare tumor that usually starts in the cells of one of your adrenal glands. although they are usually benign, pheochromocytomas often cause the adrenal gland to make too many hormones. this can lead to high blood pressure and cause symptoms such as headaches sweating pounding of the heart being shaky being extremely pale sometimes pheochromocytoma is part of another condition called multiple endocrine neoplasia syndrome (men). people with men often have other cancers and other problems involving hormones. doctors use lab tests and imaging tests to diagnose it. surgery is the most common treatment. other options include radiation therapy, chemotherapy, and targeted therapy. targeted therapy uses substances that attack cancer cells without harming normal cells. nih: national cancer institute

MalaCards: Pheochromocytoma, also known as bilateral pheochromocytoma and islet cell adenoma of the pancreas, is related to paraganglioma and von hippel-lindau disease. An important gene associated with Pheochromocytoma is SDHB (succinate dehydrogenase complex, subunit B, iron sulfur (Ip)), and among its related pathways are Metabolism and Pyruvate metabolism. The drugs propranolol and propranolol hydrochloride and the compounds vegf and tyrosine have been mentioned in the context of this disorder. Affiliated tissues include adrenal gland, testes and thyroid, and related mouse phenotypes are mortality/aging and cardiovascular system.

NIH Rare Diseases:42 Pheochromocytomas are rare tumors of the adrenal glands, which are located right above the kidneys. although they are usually not cancerous (benign), pheochromocytomas often cause the adrenal glands to make too many stress hormones called epinephrines and norepinephrines. this can lead to high blood pressure and cause symptoms such as severe headaches, irritability, sweating, rapid heart rate, nausea, vomiting, weight loss, weakness, chest pain, and a feeling of anxiety. rarely, this kind of tumor occurs outside the adrenal gland, usually somewhere in the abdomen, and are called extra-adrenal pheochromocytomas or paragangliomas. pheochromocytomas can occur in certain familial genetic syndromes. last updated: 4/27/2011

Wikipedia:63 A pheochromocytoma (from Greek phaios \"dark\", chroma \"color\", kytos \"cell\", -oma \"tumor\") or... more...

Description from OMIM:46 171300

Aliases & Classifications for Pheochromocytoma

About this section
Sources:
63Wikipedia, 42NIH Rare Diseases, 22GTR, 46OMIM, 44Novoseek, 33MedlinePlus, 60UMLS
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Endocrine diseases


Aliases & Descriptions:

pheochromocytoma 63 42 22 46 44 33 60
bilateral pheochromocytoma and islet cell adenoma of the pancreas 60
chromaffin paraganglioma 42
medullary paraganglioma 42
chromaffin cell tumor 42
chromaffin tumor 42
chromaffinoma 42


Related Diseases for Pheochromocytoma

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases in the Pheochromocytoma family:

Tmem127-Related Susceptibility to Pheochromocytoma Ret-Related Pheochromocytoma
Kif1b-Related Pheochromocytoma Vhl-Related Pheochromocytoma
Max-Related Susceptibility to Pheochromocytoma

Diseases related to Pheochromocytoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 247)
idRelated DiseaseScoreTop Affiliating Genes
1paraganglioma31.3SDHA, SDHC, SDHB, SDHD, PNMT, TH
2von hippel-lindau disease30.9SDHC, VHL, RET, SDHB, SDHD, TMEM127
3hypertension30.8TH, PNMT, ADM
4hereditary paraganglioma-pheochromocytoma syndromes30.8SDHC, SDHB, SDHD
5ganglioneuroma30.8NGF, RET, CHGA, TH
6neurofibromatosis30.7SDHC, SDHD, VHL, RET, SDHB
7thyroid medullary carcinoma30.7CHGA, RET, GDNF, VHL, SST, CHGB
8adenoma30.7CHGA, CHGB, SST, GDNF, RET, VHL
9neuroblastoma30.6NGF, TH
10adrenal adenoma30.5SDHC, ADM, CHGA, VHL, SDHB, SDHD
11cushing's syndrome30.5CHGA, RET, SST
12hyperparathyroidism30.4RET, CHGA, SDHD, SDHB, SDHC
13ganglioneuroblastoma30.3TH
14pancreatitis30.3SST
15thyroid cancer30.2RET, SST, CHGA
16familial medullary thyroid carcinoma30.2GDNF, RET
17adenocarcinoma30.2SST, CHGB, CHGA, VHL, ADM
18neuroendocrine tumor30.2CHGA, SST
19pituitary adenoma30.1CHGA, CHGB, SST, GDNF, RET, ADM
20gastrointestinal stromal tumor30.1SDHA, SDHC, SDHB
21diarrhea30.1SST, CHGA
22multiple endocrine neoplasia type 2a30.0SDHC, SDHB, RET, SDHD, VHL, GDNF
23neuroma30.0RET, GDNF
24parathyroid adenoma30.0CHGB, RET, CHGA
25phaeochromocytoma29.9SDHC, CHGA, NGF, RET, ADM, SDHD
26hemangioma29.9SDHC, SDHB, VHL, RET, SDHD
27neuropathy29.9NGF
28breast cancer29.7VHL, TH, ADM, SDHB, SDHC
29hyperthyroidism29.7SST, SDHB, SDHA, ADM
30ischemia29.7SDHB, GDNF, TH, ADM
31carney triad29.7SDHB, SDHC, SDHD
32paraganglioma and gastric stromal sarcoma29.7SDHD, SDHB, SDHC
33lung small cell carcinoma29.7SST, GDNF, CHGA, VHL
34parkinson's disease29.7PNMT, TH, GDNF, NGF
35leukemia29.7GDNF, NGF
36somatostatinoma29.7SST, CHGA
37addison's disease29.7TH
38merkel cell carcinoma29.7CHGA
39zollinger-ellison syndrome29.7SST, CHGA
40diabetic neuropathy29.6NGF, GDNF
41thyroiditis10.6
42neuronitis10.4
43adrenal carcinoma10.3
44hemangioblastoma10.2
45primary hyperparathyroidism10.2
46malignant hypertension10.2
47neurofibromatosis-pheochromocytoma-duodenal carcinoid syndrome10.2
48hyperaldosteronism10.2
49papillary carcinoma10.1
50papillary thyroid carcinoma10.1

Graphical network of the top 20 diseases related to Pheochromocytoma:



Diseases related to pheochromocytoma

Clinical Features for Pheochromocytoma

About this section
Sources:
46OMIM
See all sources

Clinical features from OMIM:

171300

Clinical synopsis from OMIM:

171300

Drugs & Therapeutics for Pheochromocytoma

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Pheochromocytoma

Drug clinical trials:

Search ClinicalTrials for Pheochromocytoma

Search NIH Clinical Center for Pheochromocytoma

Search CenterWatch for Pheochromocytoma

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Pheochromocytoma

About this section
Sources:
22GTR
See all sources

Genetic tests related to Pheochromocytoma:

id Genetic test Affiliating Genes
1 Pheochromocytoma22

Anatomical Context for Pheochromocytoma

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Pheochromocytoma:

32
Adrenal gland, Testes, Thyroid, Heart, Pancreas, Kidney, Pituitary, Endothelial, Bone, Brain, Liver, Pancreatic islet, Lung, Prostate, Cortex, Colon, Retina, B cells, Breast, Adipocyte, Eye, Skin, Adrenal cortex

Animal Models for Pheochromocytoma or affiliated genes

About this section
Sources:
36MGI
See all sources

MGI Mouse Phenotypes related to Pheochromocytoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:001076811.8GDNF, NGF, MAX, CHGA, VHL, RET
2MP:000538511.8SDHD, VHL, CHGA, NGF, GDNF, RET
3MP:000537611.6VHL, CHGA, CHGB, SST, NGF, RET
4MP:000536911.5VHL, IFRD1, NGF, GDNF, RET, KIF1B
5MP:000537811.5SST, CHGA, IFRD1, VHL, MAX, NGF
6MP:000287311.2SST, NGF, RET, TH, PNMT, SDHD
7MP:000363111.1CHGB, SST, NGF, GDNF, RET, KIF1B
8MP:000537910.7CHGB, GDNF, RET

Publications for Pheochromocytoma

About this section
Sources:
50PubMed
See all sources

Articles related to Pheochromocytoma:

(show top 50)    (show all 1225)
idTitleAuthorsYear
1
Pheochromocytoma causing cardiomyopathy, ischemic stroke and acute arterial thrombosis: a case report and review of the literature. (23513638)
2013
2
Splenectomy for splenic metastases from malignant adrenal pheochromocytoma: a case report. (23882428)
2013
3
Pheochromocytoma revealed by acute heart failure. When should we operate? Presented at the ESES Congress, Gothenburg May 25-26, 2012. (23250652)
2013
4
Child with bilateral pheochromocytoma and a surgically solitary kidney: Anesthetic challenges. (23956724)
2013
5
Successful treatment of pheochromocytoma in a patient with hemodialysis: a case report and review of the literature. (23991676)
2013
6
Multiple gastrointestinal stromal tumors and pheochromocytoma in a patient with von Recklinghausen's disease. (23287063)
2013
7
Prevalence and spectrum of SDHx mutations in pheochromocytoma and paraganglioma in patients from Belgium: an update. (22566194)
2012
8
Management of pheochromocytoma during pregnancy: laparoscopic adrenalectomy. (22524746)
2012
9
Diagnostic tests and biomarkers for pheochromocytoma and extra-adrenal paraganglioma: from routine laboratory methods to disease stratification. (22180288)
2012
10
Perioperative management of pheochromocytoma/paraganglioma: is there a state of the art? (22517559)
2012
11
Surgical management of organ-contained unilateral pheochromocytoma: comparative outcomes of laparoscopic and conventional open surgical procedures in a large single-institution series. (22120010)
2012
12
Transthoracic echocardiographic features of cardiac pheochromocytoma: a single-institution experience. (22066682)
2012
13
Prevalence of germline mutations in patients with pheochromocytoma or abdominal paraganglioma and sporadic presentation: a population-based study in Western Sweden. (22270996)
2012
14
Thrombosis of the superior mesenteric vein revealing an ectopic pheochromocytoma of the organ of Zuckerkandl. (22682785)
2012
15
Partial adrenalectomy minimizes the need for long-term hormone replacement in pediatric patients with pheochromocytoma and von Hippel-Lindau syndrome. (23164001)
2012
16
Sunitinib inhibits catecholamine synthesis and secretion in pheochromocytoma tumor cells by blocking VEGF receptor 2 via PLC-I^-related pathways. (22912364)
2012
17
Coexistence of pheochromocytoma with uncommon vascular lesions. (23226643)
2012
18
A 45-year-old female with hypokalemic rhabdomyolysis due to VIP-producing composite pheochromocytoma. (22660994)
2012
19
Parallel development and course of pheochromocytoma and giant squamous cell carcinoma of the leg: a new paraneoplastic syndrome? (22367380)
2011
20
Anesthesia for pheochromocytoma resection in a child with Fontan circulation. (21509635)
2011
21
A pheochromocytoma with high adrenocorticotropic hormone and a silent lung nodule. (21804367)
2011
22
Transarterial embolization and doxorubicin eluting beads-transarterial chemoembolization (DEB-TACE) of malignant extra-adrenal pheochromocytoma. (21437761)
2011
23
Cardiogenic shock due to pheochromocytoma rescued by extracorporeal membrane oxygenation. (21422159)
2011
24
SDHB loss predicts malignancy in pheochromocytomas/sympathethic paragangliomas, but not through hypoxia signalling. (20702724)
2010
25
Role of positron emission tomography and bone scintigraphy in the evaluation of bone involvement in metastatic pheochromocytoma and paraganglioma: specific implications for succinate dehydrogenase enzyme subunit B gene mutations. (18310297)
2008
26
Malignant pheochromocytoma in a young adult forming the structure simulating Homer Wright rosette: differentiation from neuroblastoma on repeating fluorescence in situ hybridization. (18705773)
2008
27
A "classical" homodimeric erythropoietin receptor is essential for the antiapoptotic effects of erythropoietin on differentiated neuroblastoma SH-SY5Y and pheochromocytoma PC-12 cells. (17045782)
2007
28
Mutation screening of RET proto-oncogene in Chinese sporadic patients with pheochromocytoma]. (16767674)
2006
29
Expression of connexins in chromaffin cells of normal human adrenals and in benign and malignant pheochromocytomas. (17102126)
2006
30
Differential expression of human telomerase catalytic subunit mRNA by in situ hybridization in pheochromocytomas. (17525487)
2006
31
Molecular implications of RET mutations for pheochromocytoma risk in multiple endocrine neoplasia 2. (17102091)
2006
32
Cutaneous metastasis of pheochromocytoma in multiple endocrine neoplasia IIB. (16844526)
2006
33
The effects of urotensin-II on proliferation of pheochromocytoma cells and mRNA expression of urotensin-II and its receptor in pheochromocytoma tissues. (17102097)
2006
34
Unsuspected pheochromocytoma: von Hippel-Lindau disease. (14676566)
2004
35
Expression of mRNA for PACAP and its receptors in intra- and extra-adrenal human pheochromocytomas and their relationship to catecholamine synthesis. (12573802)
2003
36
Cellular localization of orexin receptors in human adrenal gland, adrenocortical adenomas and pheochromocytomas. (11830291)
2002
37
Metastatic brainstem pheochromocytoma in a patient with von Hippel-Lindau disease. Case illustration. (11147885)
2001
38
Bilateral pheochromocytoma associated with duodeno-jejunal GIST in patient with von Recklinghausen disease: report of a clinical case]. (11396074)
2001
39
VIP-Related protection against lodoacetate toxicity in pheochromocytoma (PC12) cells: a model for ischemic/hypoxic injury. (11303779)
2000
40
Differences in allelic distribution of two polymorphisms in the VHL-associated gene CUL2 in pheochromocytoma patients without somatic CUL2 mutations. (10487688)
1999
41
Activation of sphingosine kinase in pheochromocytoma PC12 neuronal cells in response to trophic factors. (9395290)
1997
42
Remarkably suppressed manganese superoxide dismutase activity in malignant pheochromocytoma. (7752317)
1995
43
Rudolf-Virchow-Preis 1995. The role of RET proto-oncogene mutation analysis in the diagnosis of multiple endocrine neoplasia type 2 (MEN 2) gene carriers and in the discrimination of sporadic and familial medullary thyroid carcinomas and pheochromocytomas. (8600671)
1995
44
Pheochromocytoma associated with polycythemia: case report. (7502017)
1995
45
Dopamine D2 receptor gene expression and binding sites in adrenal medulla and pheochromocytoma. (8027253)
1994
46
Detection of RET proto-oncogene point mutations in paraffin-embedded pheochromocytoma specimens by nonradioactive single-strand conformation polymorphism analysis and direct sequencing. (7943181)
1994
47
Okadaic acid stimulates the activity of microtubule associated protein kinase in PC-12 pheochromocytoma cells. (2161219)
1990
48
Bilateral adrenal pheochromocytoma. Diagnosis and follow-up using the clonidine test and measurement of plasma neuropeptide Y concentration]. (2233767)
1990
49
Pheochromocytoma-ganglioneuroma of the adrenal. (3838664)
1985
50
Pheochromocytoma, medullary thyroid carcinoma, multiple mucosal neuroma. A variant of the syndrome. (4623875)
1972

Genetic Variations for Pheochromocytoma

About this section
Sources:
62UniProtKB/Swiss-Prot
See all sources

Genetic disease variations for Pheochromocytoma:

62 (show all 45)
id Symbol AA change Variation ID SNP ID
1RETp.Cys634GlyVAR_006323
2RETp.Cys634PheVAR_006324
3RETp.Cys634TyrVAR_006325
4RETp.Cys634ArgVAR_006326
5RETp.Cys634SerVAR_006327
6RETp.Cys634TrpVAR_006328
7RETp.Tyr791PheVAR_009483rs77724903
8SDHBp.Arg242HisVAR_017869
9SDHBp.Leu87SerVAR_018517
10SDHBp.Arg46GlyVAR_035064
11SDHBp.Cys101TyrVAR_035065
12SDHBp.Cys192ArgVAR_035066
13SDHBp.Cys196TyrVAR_035067
14SDHBp.Ser100PheVAR_037620
15SDHBp.Ala43ProVAR_054376
16SDHBp.Arg46GlnVAR_054377
17SDHBp.Gly53ArgVAR_054378
18SDHBp.Leu65HisVAR_054379
19SDHBp.Leu65ProVAR_054380
20SDHBp.Ile127AsnVAR_054381
21SDHBp.Arg230CysVAR_054383rs138996609
22SDHDp.Pro81LeuVAR_010038
23SDHDp.Asp92TyrVAR_010039
24VHLp.Ser68TrpVAR_005675
25VHLp.Ser80AsnVAR_005688rs5030805
26VHLp.Gly93CysVAR_005703rs5030808
27VHLp.Gly93SerVAR_005705rs5030808
28VHLp.Tyr98HisVAR_005707rs5030809
29VHLp.Phe119LeuVAR_005728
30VHLp.Phe136CysVAR_005737rs5030833
31VHLp.Tyr156CysVAR_005743
32VHLp.Arg161GlnVAR_005751
33VHLp.Arg161ProVAR_005752
34VHLp.Arg167GlnVAR_005761rs5030821
35VHLp.Arg167TrpVAR_005762rs5030820
36VHLp.Leu188ValVAR_005777rs5030824
37VHLp.Pro25LeuVAR_034562rs35460768
38VHLp.Leu63ProVAR_034987
39VHLp.Arg64ProVAR_034988
40VHLp.Ser65AlaVAR_034989
41VHLp.Arg107GlyVAR_034991
42VHLp.Ala122IleVAR_034993
43VHLp.Ile147ThrVAR_034996
44VHLp.Tyr156AsnVAR_034997
45VHLp.Leu198GlnVAR_035001

Expression for genes affiliated with Pheochromocytoma

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Pheochromocytoma

Search GEO for disease gene expression data for Pheochromocytoma.

Pathways for genes affiliated with Pheochromocytoma

About this section
Sources:
53Reactome, 29KEGG, 12EMD Millipore, 37NCBI BioSystems Database, 4Cell Signaling Technology
See all sources

Compounds for genes affiliated with Pheochromocytoma

About this section
Sources:
44Novoseek, 11DrugBank, 24HMDB, 49PharmGKB, 28IUPHAR, 59Tocris Bioscience
See all sources

Compounds related to Pheochromocytoma according to GeneCards/GeneDecks:

(show top 50)    (show all 73)
idCompoundScoreTop Affiliating Genes
1vegf4411.9VHL, CHGA, SST, NGF, GDNF, RET
2tyrosine4411.9VHL, CHGA, CHGB, NGF, GDNF, RET
3catecholamine4411.8SDHB, CHGA, CHGB, GDNF, RET, TH
4norepinephrine44 11 2413.8CHGA, CHGB, SST, NGF, GDNF, TH
5oxygen44 2412.8VHL, CHGA, GDNF, TH, ADM, SDHD
6retinoic acid44 2412.6CHGA, SST, NGF, GDNF, RET, TH
7epinephrine44 11 2413.6CHGA, SST, NGF, TH, PNMT, ADM
8acetylcholine44 49 28 11 2415.6CHGA, SST, NGF, GDNF, TH, PNMT
9iron44 2412.6VHL, GDNF, TH, SDHD, SDHB, SDHC
10adenylate4411.6CHGA, SST, NGF, GDNF, RAMP2, TH
11testosterone44 59 11 2414.5CHGA, SST, SDHB, ADM, TH, RET
12mibg4411.5CHGA, SST, TH, ADM, SDHD, SDHB
13succinate4411.5VHL, RET, SDHD, SDHB, SDHC, SDHA
14dopamine44 28 11 2414.5CHGA, CHGB, GDNF, TH, PNMT, SDHB
15levodopa44 1112.5CHGA, SST, NGF, GDNF, TH, PNMT
16histamine44 28 2413.5CHGA, SST, NGF, TH, PNMT, ADM
17cysteine4411.5CHGA, NGF, GDNF, RET, TH, ADM
18glucose4411.4VHL, CHGA, SST, GDNF, UTS2R, ADM
19dexamethasone44 49 28 1114.4CHGB, GDNF, RAMP2, TH, PNMT
20cyclic amp44 2412.4CHGA, NGF, GDNF, RET, TH, ADM
21carbachol44 28 1113.4CHGA, SST, NGF, TH, ADM
22choline44 11 2413.4SST, NGF, GDNF, RET, TH
23nicotine44 49 28 1114.3VHL, CHGA, NGF, TH, PNMT
24UBIQUINONE-11111.3SDHD, SDHB, SDHC, SDHA
252-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol1111.3SDHD, SDHB, SDHC, SDHA
26fumarate44 1112.3VHL, SDHD, SDHB, SDHC
27oligonucleotide4411.3VHL, CHGA, CHGB, GDNF, RET, ADM
28succinic acid28 11 2413.3SDHA, SDHC, SDHB, SDHD
29l-amino acid4411.3CHGA, GDNF, TH, PNMT
30iron-sulfur4411.3SDHD, SDHB, SDHC, SDHA
31ubiquinone4411.3SDHD, SDHB, SDHC, SDHA
32ly2940024411.3TH, RET, GDNF, NGF, VHL
33mptp4411.2SST, NGF, GDNF, TH
34forskolin44 49 1113.2ADM, TH, GDNF, MAX
35actinomycin d4411.2VHL, NGF, GDNF, TH, ADM
36propranolol44 28 49 11 2415.2CHGA, SST, NGF, ADM
37arginine4411.1CHGA, SST, NGF, RET, ADM, SDHB
385-hydroxytryptamine4411.1CHGA, SST, TH, PNMT
39peptidylglycine4411.1CHGA, CHGB, ADM
405-hydroxytryptophan4411.1TH, SST, CHGA
41selegiline44 1112.1TH, GDNF, NGF
42acth4411.0CHGA, CHGB, SST, ADM
43cipa4411.0NGF, RET
44streptozotocin4411.0ADM, SST, CHGA
45amphetamine44 1112.0SST, GDNF, TH
466-hydroxydopamine4410.9NGF, GDNF, TH
47lactate4410.9CHGA, SST, TH, ADM, SDHB
48normetanephrine44 2411.7PNMT, CHGA
49gnrh4410.7TH, CHGA
50clonidine44 28 1112.5PNMT, SST, CHGA

GO Terms for genes affiliated with Pheochromocytoma

About this section
Sources:
16Gene Ontology
See all sources

Cellular components related to Pheochromocytoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1mitochondrionGO:00573910.9VHL, KIF1B, TH, SDHD, SDHB, SDHC
2mitochondrial inner membraneGO:00574310.9SDHA, SDHC, SDHB, SDHD
3mitochondrial respiratory chain complex IIGO:00574910.8SDHA, SDHC, SDHB, SDHD

Biological processes related to Pheochromocytoma according to GeneCards/GeneDecks:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1tricarboxylic acid cycleGO:00609911.2SDHA, SDHC, SDHB, SDHD
2respiratory electron transport chainGO:02290411.1SDHA, SDHC, SDHB, SDHD
3cellular metabolic processGO:04423711.1SDHA, SDHC, SDHB, SDHD
4epinephrine biosynthetic processGO:04241810.9TH, PNMT
5vascular smooth muscle cell developmentGO:09708410.9ADM, RAMP2
6catecholamine biosynthetic processGO:04242310.9TH, PNMT
7succinate metabolic processGO:00610510.8SDHA, SDHB
8positive regulation of vasculogenesisGO:200121410.8ADM, RAMP2
9response to lipopolysaccharideGO:03249610.8ADM, TH, NGF
10negative regulation of vascular permeabilityGO:04311610.7RAMP2, ADM
11cAMP biosynthetic processGO:00617110.7RAMP2, ADM
12positive regulation of angiogenesisGO:04576610.7RAMP2, UTS2R, ADM
13response to electrical stimulusGO:05160210.4TH, NGF

Molecular functions related to Pheochromocytoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:00517910.8ADM, SST, CHGB
2succinate dehydrogenase (ubiquinone) activityGO:00817710.6SDHA, SDHB
3ubiquinone bindingGO:04803910.4SDHB, SDHD

Products for genes affiliated with Pheochromocytoma

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Pheochromocytoma

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet