MCID: PHM001
MIFTS: 36

Phimosis malady

Summaries for Phimosis

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63Wikipedia, 32MalaCards
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Wikipedia:63 Phimosis (/fɪˈmoʊsɨs/ or /faɪˈmoʊsɨs/), from the Greek phimos (φῑμός [\"muzzle\"]), is a... more...

MalaCards: Phimosis, also known as acquired phimosis, is related to balanitis and diabetes mellitus. An important gene associated with Phimosis is FOXL2 (forkhead box L2), and among its related pathways are Elastic fibre formation and Cell adhesion Endothelial cell contacts by non-junctional mechanisms. The compounds tc-i 15 and obtustatin have been mentioned in the context of this disorder. Affiliated tissues include bone, skin and pituitary.

Aliases & Classifications for Phimosis

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8Disease Ontology, 10DISEASES, 60UMLS, 34MeSH, 56SNOMED-CT, 39NCIt
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Aliases & Descriptions:

phimosis 8 10
acquired phimosis 60
tight frenulum 8
tight foreskin 8


External Ids:

Disease Ontology8 DOID:2712
MeSH34 D010688
NCIt39 C26852

Related Diseases for Phimosis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Phimosis:



Diseases related to phimosis

Clinical Features for Phimosis

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Drugs & Therapeutics for Phimosis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Phimosis

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Anatomical Context for Phimosis

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32MalaCards
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MalaCards organs/tissues related to Phimosis:

32
Bone, Skin, Pituitary, Bone marrow, Eye, Kidney

Animal Models for Phimosis or affiliated genes

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Publications for Phimosis

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50PubMed
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Articles related to Phimosis:

(show top 50)    (show all 202)
idTitleAuthorsYear
1
Congenital phimosis in patients with and without lichen sclerosus: distinct expression patterns of tissue remodeling associated genes. (23174236)
2013
2
Re: Predictive power of objectivation of phimosis grade on outcomes of topical 0.1% betamethasone treatment of phimosis. (24029358)
2013
3
Enlargement lateral posthetectomy for phimosis in the infant: a new approach. (22503478)
2012
4
Phimosis in children. (23002427)
2012
5
Severe phimosis leading to obstructive uropathy in a boy with lichen sclerosus. (22594961)
2012
6
Predictive power of objectivation of phimosis grade on outcomes of topical 0.1% betamethasone treatment of phimosis. (22749426)
2012
7
Local steroid therapy as the first-line treatment for boys with symptomatic phimosis - a long-term prospective study. (22103624)
2012
8
Prepuce: phimosis, paraphimosis, and circumcision. (21298220)
2011
9
Laser treatment alternative to IOL exchange for capsulorhexis phimosis with anterior flexing of single-piece hydrophilic acrylic IOL haptics. (21111343)
2010
10
Rapid capsular phimosis in retinitis pigmentosa. (20726501)
2010
11
Clinicopathologic correlation of capsulorhexis phimosis with anterior flexing of single-piece hydrophilic acrylic intraocular lens haptics. (20692577)
2010
12
Phimosis in cats: 10 cases (2000-2008). (19887385)
2009
13
Unilateral capsular phimosis with an acrylic IOL and two capsular tension rings in pseudoexfoliation. (19702720)
2009
14
Long-term efficiency of skin stretching and a topical corticoid cream application for unretractable foreskin and phimosis in prepubertal boys. (19172103)
2009
15
Capsular phimosis with complete occlusion of the anterior capsular opening after intact continuous curvilinear capsulorrhexis. (23960856)
2009
16
Outcome and recurrence in treatment of phimosis using topical betamethasone in children in Hong Kong. (17207060)
2007
17
Frenular grafting: an alternative to circumcision in men with a combination of tight frenulum and phimosis. (17451486)
2007
18
Histoplasma phimosis: an uncommon presentation of a not uncommon pathogen. (17519632)
2007
19
Radiotherapy for rectal carcinoma: an unusual cause of foreskin phimosis. (17115249)
2006
20
Expression of alpha 1 and beta 3 integrins subunits in the endometrium of patients with tubal phimosis or hydrosalpinx. (16412752)
2006
21
Phimosis as a presenting manifestation of genital involvement in leprosy. (15217313)
2004
22
Outpatient management of phimosis following newborn circumcision. (12771793)
2003
23
Circumcision for phimosis and other medical indications in Western Australian boys. (12580740)
2003
24
Circumcision for phimosis and other medical indications in Western Australian boys. (12830811)
2003
25
Circumcision for phimosis and other medical indications in Western Australian boys. (12830813)
2003
26
Surgical correction of phimosis in the etruscan period. (15043075)
2003
27
Lateral preputioplasty for phimosis. 1999; 45(5): 210-12. (10822927)
2000
28
Phimosis after penile Mondor's phlebitis. (10210588)
1999
29
Phimosis of infants and young children in Japan. (9316279)
1997
30
Phimosis. (9926584)
1997
31
Phimosis: is circumcision necessary? (8844530)
1996
32
Phimosis or congenital megaprepuce? (8032850)
1994
33
Adhesion of the labia minora (female phimosis or urocolpos) in the elderly. (8009185)
1994
34
The treatment of childhood phimosis with topical steroid. (8179528)
1994
35
Lichen planus: an unusual cause of phimosis. (1350142)
1992
36
Phimosis associated with mycosis fungoides. (2265345)
1990
37
Jogger's phimosis. (2731015)
1989
38
Circumcision for phimosis--indications and results. (3962664)
1986
39
Foreskin fallacies and phimosis. (4083801)
1985
40
Lichen sclerosus et atrophicus. A common and distinctive cause of phimosis in boys. (6465907)
1984
41
A new operation for phimosis: prepuce-saving technique with multiple Y-V-plasties. (6544618)
1984
42
Silica granuloma at the site of circumcision for phimosis: a case report. (6307765)
1983
43
Phimosis in boys. (7191744)
1980
44
Dorsal incision of the prepuce and skin closure with Dexon in patients with phimosis. (4586345)
1973
45
Diabetes presenting with phimosis. (4107619)
1971
46
Further fate of the foreskin. Incidence of preputial adhesions, phimosis, and smegma among Danish schoolboys. (5689532)
1968
47
Acquired phimosis in the elderly caused by lichen sclerosus et atrophicus. (13651651)
1959
48
"Phimosis Corticis Atrophica" and "Myocallositis Chronica": Two Infrequently Recognized Causes of Cerebral Insufficiency. (20893743)
1955
49
Phimosis as a CaA1se of Hernia in Infants. (20749822)
1881
50
The Treatment of Phimosis by Dilatation. (20748354)
1876

Genetic Variations for Phimosis

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Expression for genes affiliated with Phimosis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Phimosis

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Pathways for genes affiliated with Phimosis

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53Reactome, 12EMD Millipore
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Pathways related to Phimosis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
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9.8ELN, ITGB3
2
Cell adhesion Endothelial cell contacts by non-junctional mechanisms
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9.3ITGB3, ITGA1

Compounds for genes affiliated with Phimosis

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59Tocris Bioscience
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Compounds related to Phimosis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1tc-i 15599.4ITGB3, ITGA1
2obtustatin599.3ITGB3, ITGA1
3leukadherin 1599.3ITGA1, ITGB3
4a 286982599.2ITGA1, ITGB3
5bio 1211599.0ITGA1, ITGB3

GO Terms for genes affiliated with Phimosis

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16Gene Ontology
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Cellular components related to Phimosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1integrin complexGO:0083059.3ITGB3, ITGA1

Products for genes affiliated with Phimosis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Phimosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet