MCID: PHM001
MIFTS: 40

Phimosis malady

Reproductive diseases category

Summaries for Phimosis

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Sources:
66Wikipedia, 34MalaCards
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Wikipedia:66 Phimosis (/f??mo?s?s/ or /fa??mo?s?s/), from the Greek phimos (????? [\"muzzle\"]), is a condition in... more...

MalaCards: Phimosis, also known as acquired phimosis, is related to lichen sclerosus and balanitis. An important gene associated with Phimosis is FLAD1 (flavin adenine dinucleotide synthetase 1), and among its related pathways are Elastic fibre formation and Cell adhesion ECM remodeling. The compounds tc-i 15 and obtustatin have been mentioned in the context of this disorder. Affiliated tissues include bone, skin and pituitary.

Aliases & Classifications for Phimosis

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Sources:
9Disease Ontology, 11DISEASES, 63UMLS, 59SNOMED-CT, 41NCIt, 36MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Reproductive diseases


Aliases & Descriptions:

phimosis 9 11
acquired phimosis 63
tight frenulum 9
tight foreskin 9


External Ids:

Disease Ontology9 DOID:2712
NCIt41 C26852
MeSH36 D010688

Related Diseases for Phimosis

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Sources:
18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Phimosis:



Diseases related to phimosis

Symptoms for Phimosis

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Drugs & Therapeutics for Phimosis

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Phimosis

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Anatomical Context for Phimosis

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Sources:
34MalaCards
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MalaCards organs/tissues related to Phimosis:

34
Bone, Skin, Pituitary, Bone marrow, Eye, Kidney

Animal Models for Phimosis or affiliated genes

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Publications for Phimosis

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53PubMed
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Articles related to Phimosis:

(show top 50)    (show all 202)
idTitleAuthorsYear
1
Prepuce-sparing plasty and simple running suture for phimosis. (23463932)
2013
2
Acute presentation of clitoral phimosis in a 16-year-old girl. (24127974)
2013
3
Anterior capsular phimosis occluding the capsulorhexis opening after cataract surgery in a diabetic patient with high hemoglobin A1C. (23448558)
2013
4
Role of human papillomaviruses in persistent and glucocorticoid-resistant juvenile phimosis. (22471970)
2013
5
Incidence of balanitis xerotica obliterans in boys younger than 10 years presenting with phimosis. (23296396)
2013
6
An unusual case of foreskin phimosis after radiotherapy for rectal carcinoma. (22721756)
2012
7
Topical mometasone furoate for phimosis. (20371899)
2010
8
Phimosis in cats: 10 cases (2000-2008). (19887385)
2009
9
Conservative treatment of phimosis with fluticasone proprionate 0.05%: a clinical study in 1185 boys. (19097823)
2009
10
Topical triamcinolone for persistent phimosis. (19692044)
2009
11
A new approach in the surgical management of anterior capsular phimosis syndrome. (19672131)
2009
12
Unilateral capsular phimosis with an acrylic IOL and two capsular tension rings in pseudoexfoliation. (19702720)
2009
13
Topical steroid application versus circumcision in pediatric patients with phimosis: a prospective randomized placebo controlled clinical trial. (18157674)
2008
14
Phimosis as a presenting feature of diabetes. (18005214)
2008
15
Pathologic and physiologic phimosis: approach to the phimotic foreskin. (17872680)
2007
16
Outcome and recurrence in treatment of phimosis using topical betamethasone in children in Hong Kong. (17207060)
2007
17
Phimosis: stretching methods with or without application of topical steroids? (16291369)
2005
18
Phimosis as a presenting manifestation of genital involvement in leprosy. (15217313)
2004
19
Triple incision to treat phimosis in children: an alternative to circumcision. (15008749)
2004
20
Outpatient management of phimosis following newborn circumcision. (12771793)
2003
21
Circumcision for phimosis and other medical indications in Western Australian boys. (12580740)
2003
22
Circumcision for phimosis and other medical indications in Western Australian boys. (12765511)
2003
23
Circumcision for phimosis and other medical indications in Western Australian boys. (12830812)
2003
24
A conservative treatment of phimosis in boys. (11528198)
2001
25
Cost-effectiveness analysis of treatments for phimosis: a comparison of surgical and medicinal approaches and their economic effect. (11167650)
2001
26
Conservative treatment of childhood phimosis with topical conjugated equine estrogen ointment. (10701883)
2000
27
La Vega slit procedure for the treatment of phimosis. (10699624)
2000
28
Cost-effective treatment of phimosis. (9755280)
1998
29
Local anaesthesia with eutectic cream of lidocaine and prilocaine for treatment of cicatrizial phimosis in outpatients. (10710821)
1998
30
Phimosis of infants and young children in Japan. (9316279)
1997
31
Phimosis. (9926584)
1997
32
Phimosis: is circumcision necessary? (8844530)
1996
33
Epispadias with phimosis: an unusual variant of the concealed penis. (7817473)
1995
34
Treatment of childhood phimosis with topical steroid. (7818425)
1995
35
Treatment of childhood phimosis with topical steroid. (7980263)
1994
36
Phimosis or congenital megaprepuce? (8032850)
1994
37
Is phimosis overdiagnosed in boys and are too many circumcisions performed in consequence? (2802472)
1989
38
Jogger's phimosis. (2731015)
1989
39
Carcinoma of penis--role of phimosis. (6740858)
1984
40
Silica granuloma at the site of circumcision for phimosis: a case report. (6307765)
1983
41
Phimosis: a cause of renal failure. (6580459)
1983
42
Phimosis in boys. (7191744)
1980
43
Phimosis hook. (375539)
1979
44
Candiduria in children. Report of two cases in boys with phimosis. (1218950)
1975
45
Radiological case of the month. Unusual presentation of phimosis. (4440653)
1974
46
New microcirculatory constrictive therapy for phimosis and associated disorders. (14406590)
1959
47
Surgical treatment of congenital palpebral phimosis; the Y-V operation. (13257989)
1955
48
"Phimosis Corticis Atrophica" and "Myocallositis Chronica": Two Infrequently Recognized Causes of Cerebral Insufficiency. (20893743)
1955
49
Phimosis from the Flesh Fly. (20323665)
1946
50
Phimosis from the flesh fly, Wohlfahrtia vigil. (21007210)
1946

Variations for Phimosis

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Expression for genes affiliated with Phimosis

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Phimosis

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Pathways for genes affiliated with Phimosis

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Sources:
51PathCards, 56Reactome, 61Thomson Reuters, 13EMD Millipore, 31KEGG, 54QIAGEN, 39NCBI BioSystems Database
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Compounds for genes affiliated with Phimosis

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Sources:
62Tocris Bioscience, 46Novoseek, 25HMDB, 12DrugBank
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Compounds related to Phimosis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1tc-i 15629.6ITGA1, ITGB3
2obtustatin629.5ITGB3, ITGA1
3a 286982629.5ITGB3, ITGA1
4bio 1211629.4ITGB3, ITGA1
5leukadherin 1629.3ITGB3, ITGA1
6magnesium46 25 1211.1ITGA1, ELN, FLAD1
7lysine468.7ELN, ITGB3, ITGA1

GO Terms for genes affiliated with Phimosis

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17Gene Ontology
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Cellular components related to Phimosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1integrin complexGO:0083059.4ITGA1, ITGB3

Biological processes related to Phimosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1integrin-mediated signaling pathwayGO:0072299.4ITGA1, ITGB3
2extracellular matrix organizationGO:0301988.7ITGA1, ITGB3, ELN

Products for genes affiliated with Phimosis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Phimosis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet