MCID: PHM001
MIFTS: 36

Phimosis malady

Summaries for Phimosis

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63Wikipedia, 32MalaCards
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Wikipedia:63 Phimosis (/fɪˈmoʊsɨs/ or /faɪˈmoʊsɨs/), from the Greek phimos (φῑμός [\"muzzle\"]), is a... more...

MalaCards: Phimosis, also known as acquired phimosis, is related to balanitis and diabetes mellitus. An important gene associated with Phimosis is FOXL2 (forkhead box L2), and among its related pathways are Elastic fibre formation and Cell adhesion Endothelial cell contacts by non-junctional mechanisms. The compounds tc-i 15 and obtustatin have been mentioned in the context of this disorder. Affiliated tissues include skin, bone and pituitary.

Aliases & Classifications for Phimosis

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8Disease Ontology, 10DISEASES, 60UMLS, 34MeSH, 56SNOMED-CT, 39NCIt
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Aliases & Descriptions:

phimosis 8 10
acquired phimosis 60
tight frenulum 8
tight foreskin 8


External Ids:

Disease Ontology8 DOID:2712
MeSH34 D010688
NCIt39 C26852

Related Diseases for Phimosis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Phimosis:



Diseases related to phimosis

Clinical Features for Phimosis

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Drugs & Therapeutics for Phimosis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Phimosis

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Anatomical Context for Phimosis

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32MalaCards
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MalaCards organs/tissues related to Phimosis:

32
Skin, Bone, Pituitary, Kidney, Eye, Bone marrow

Animal Models for Phimosis or affiliated genes

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Publications for Phimosis

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50PubMed
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Articles related to Phimosis:

(show top 50)    (show all 202)
idTitleAuthorsYear
1
Is half strength of 0.05A % betamethasone valerate cream still effective in the treatment of phimosis in young children? (23292538)
2013
2
Phimosis in childhood. (23788454)
2013
3
Structural analysis of the phimotic prepuce in patients with failed topical treatment compared with untreated phimosis. (23302400)
2012
4
A novel approach to the surgical management of clitoral phimosis. (22555140)
2012
5
Topical mometasone furoate for phimosis. (20371899)
2010
6
Is suppression of hypothalamic-pituitary-adrenal axis significant during clinical treatment of phimosis? (20400146)
2010
7
Topical steroid is effective for the treatment of phimosis in young children. (20196415)
2010
8
Phimosis and scrotal lesions in leprosy: two case reports. (19842435)
2009
9
Anterior capsule phimosis and capsular block syndrome in a patient with Steinert myotonic dystrophy: a case report. (20062622)
2009
10
Phimosis as a presenting feature of diabetes. (18005214)
2008
11
Lichen sclerosus et atrophicus in pediatric and adult male patients with congenital and acquired phimosis. (18660641)
2008
12
Y-V preputioplasty for adult phimosis: a review of 89 cases. (18701144)
2008
13
Capsulorhexis phimosis after bimanual microphacoemulsification and in-the-bag implantation of the Akreos MI60 intraocular lens. (18721727)
2008
14
Y-V plasty of the foreskin as an alternative to circumcision for surgical treatment of phimosis during childhood. (18947698)
2007
15
To circ or not to circ: indications, risks, and alternatives to circumcision in the pediatric population with phimosis. (16800325)
2006
16
Topical hydrocortisone and physiotherapy for nonretractile physiologic phimosis in infants. (16791612)
2006
17
Preputial bacterial flora and its relation with phimosis. (16493227)
2006
18
Treatment of phimosis with topical steroids and foreskin anatomy. (16137407)
2005
19
Triple incision to treat phimosis in children: an alternative to circumcision. (15008749)
2004
20
A new technique for correction of disproportionate preputial growth with phimosis. (15205897)
2004
21
Triple incision to treat phimosis in children: an alternative to circumcision? (12930440)
2003
22
Treating phimosis. (12580737)
2003
23
Lichen sclerosus et atrophicus in children with phimosis and hypospadias. (12021978)
2002
24
Cicatricial pemphigoid-induced phimosis. (12004290)
2002
25
Phimosis revealed by contamination with radioactive urine on bone scintigraphy. (11595870)
2001
26
La Vega slit procedure for the treatment of phimosis. (10699624)
2000
27
Inflammatory phimosis. (20877019)
2000
28
The incidence of phimosis in boys. (10444134)
1999
29
Medical management of phimosis in children: our experience with topical steroids. (10458456)
1999
30
Cost-effective treatment of phimosis. (9755280)
1998
31
Phimosis as a manifestation of chronic graft-versus-host disease after allogeneic bone marrow transplantation. (9578313)
1998
32
A nonsurgical approach to the treatment of phimosis: local nonsteroidal anti-inflammatory ointment application. (9186358)
1997
33
Epispadias with phimosis: an unusual variant of the concealed penis. (7817473)
1995
34
A new method for the relief of adult phimosis. (7714983)
1995
35
Treatment of childhood phimosis with topical steroid. (7980263)
1994
36
Lichen sclerosus et atrophicus causing phimosis in boys: a prospective study with 5-year followup after complete circumcision. (8051779)
1994
37
Accelerated hypertension caused by severe phimosis. (1597850)
1992
38
Radiological case of the month. Pathologic phimosis. (1595636)
1992
39
The histologic spectrum of prepuces from patients with phimosis. (3239715)
1988
40
Epispadias with complete prepuce and phimosis in a neonate. (3791838)
1987
41
Phimosis of the prepuce of the clitoris: indication for female circumcision. (3973892)
1985
42
Carcinoma of penis--role of phimosis. (6740858)
1984
43
Phimosis and diabetes mellitus. (7087016)
1982
44
Phimosis hook. (375539)
1979
45
Candiduria in children. Report of two cases in boys with phimosis. (1218950)
1975
46
Obstructive uropathy secondary to phimosis and balanoposthitis. (5422861)
1970
47
Phimosis with balanoposthitis in previously undiagnosed diabetes mellitus. (5683645)
1968
48
New microcirculatory constrictive therapy for phimosis and associated disorders. (14406590)
1959
49
Phimosis from the flesh fly, Wohlfahrtia vigil. (21007210)
1946
50
Treatment of Gonorrhoea, Balanitis, and Acquired Phimosis. (20784251)
1942

Genetic Variations for Phimosis

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Expression for genes affiliated with Phimosis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Phimosis

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Pathways for genes affiliated with Phimosis

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53Reactome, 12EMD Millipore
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Pathways related to Phimosis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
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9.8ELN, ITGB3
2
Cell adhesion Endothelial cell contacts by non-junctional mechanisms
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9.3ITGB3, ITGA1

Compounds for genes affiliated with Phimosis

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59Tocris Bioscience
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Compounds related to Phimosis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1tc-i 15599.4ITGB3, ITGA1
2obtustatin599.3ITGB3, ITGA1
3leukadherin 1599.3ITGA1, ITGB3
4a 286982599.2ITGA1, ITGB3
5bio 1211599.0ITGA1, ITGB3

GO Terms for genes affiliated with Phimosis

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16Gene Ontology
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Cellular components related to Phimosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1integrin complexGO:0083059.3ITGB3, ITGA1

Products for genes affiliated with Phimosis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Phimosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet