MCID: PHB001
MIFTS: 30

Phobic Disorder malady

Neuronal diseases category

Summaries for Phobic Disorder

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Sources:
8Disease Ontology, 63Wikipedia, 32MalaCards
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Wikipedia:63 A phobia (from the Greek: φόβος, Phóbos, meaning \"fear\" or \"morbid fear\") is, when used in the... more...

MalaCards: Phobic Disorder, also known as phobic anxiety disorder, is related to panic disorder and anxiety disorder. An important gene associated with Phobic Disorder is TMPO (thymopoietin). The drugs gabapentin and paroxetine and the compounds inositol 1,4,5 trisphosphate and methionine have been mentioned in the context of this disorder.

Disease Ontology:8 An anxiety disorder where fear and anxiety are triggered by a specific stimulus or situation.

Aliases & Classifications for Phobic Disorder

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Sources:
8Disease Ontology, 60UMLS, 56SNOMED-CT, 34MeSH, 27ICD9CM, 39NCIt, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


Aliases & Descriptions:

phobic disorder 8
phobic anxiety disorder 60


Related Diseases for Phobic Disorder

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Phobic Disorder via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 11)
idRelated DiseaseScoreTop Affiliating Genes
1panic disorder10.2
2anxiety disorder10.2
3social phobia10.0
4agoraphobia10.0
5anorexia nervosa10.0
6alcohol dependence10.0
7personality disorder10.0
8specific phobia10.0
9substance dependence10.0
10atopic dermatitis10.0TMPO, BDNF
11congenital fibrosarcoma10.0GOLGA6A, GOLGA6B

Graphical network of diseases related to Phobic Disorder:



Diseases related to phobic disorder

Clinical Features for Phobic Disorder

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Drugs & Therapeutics for Phobic Disorder

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Phobic Disorder

Drug clinical trials:

Search ClinicalTrials for Phobic Disorder

Search NIH Clinical Center for Phobic Disorder

Search CenterWatch for Phobic Disorder

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Phobic Disorder

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Anatomical Context for Phobic Disorder

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Animal Models for Phobic Disorder or affiliated genes

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Publications for Phobic Disorder

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Sources:
50PubMed
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Articles related to Phobic Disorder:

(show all 14)
idTitleAuthorsYear
1
Validation of the diagnoses of panic disorder and phobic disorders in the US National Comorbidity Survey Replication Adolescent (NCS-A) supplement. (21495110)
2011
2
Genetic association between BDNF gene polymorphisms and phobic disorders: a case-control study among mainland Han Chinese. (21295349)
2011
3
The effectiveness of anxiety treatment on alcohol-dependent patients with a comorbid phobic disorder: a randomized controlled trial. (15897725)
2005
4
Association studies of MAO-A, COMT, and 5-HTT genes polymorphisms in patients with anxiety disorders of the phobic spectrum. (15450911)
2004
5
Blood-injury related phobic avoidance as predictor of nonresponse to pharmacotherapy in panic disorder with agoraphobia. (15013247)
2004
6
Temporal relationship between the age of onset of phobic disorders and development of substance dependence in adolescent psychiatric patients. (15283954)
2004
7
A polymorphic genomic duplication on human chromosome 15 is a susceptibility factor for panic and phobic disorders. (11509185)
2001
8
Social and personal resources and the prevalence of phobic disorder in a community population. (10883724)
2000
9
The longitudinal study of phobic disorder in a community sample from early to late adolescence. (11018436)
2000
10
Phobic disorder, psychotherapy, and risk-taking: an economic perspective. (10180917)
1998
11
Frequency of phobic disorder in a community sample of young adolescents. (7559315)
1995
12
Role of thymic hormones in neuroimmunomodulation. Their use in patients with phobic disorders. (1776534)
1991
13
Administration of thymopentin to patients with phobic disorders improves depressed phagocytic functions. (2092042)
1990
14
Is anorexia nervosa a phobic disorder? A psychophysiological enquiry. (7417632)
1980

Genetic Variations for Phobic Disorder

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Expression for genes affiliated with Phobic Disorder

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Phobic Disorder

Search GEO for disease gene expression data for Phobic Disorder.

Pathways for genes affiliated with Phobic Disorder

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Compounds for genes affiliated with Phobic Disorder

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Sources:
44Novoseek, 59Tocris Bioscience, 28IUPHAR, 11DrugBank
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Compounds related to Phobic Disorder according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1inositol 1,4,5 trisphosphate449.3TMPO, BDNF
2methionine449.3TMPO, BDNF
3acth449.2TMPO, BDNF
4indomethacin44 59 28 1112.0TMPO, BDNF

GO Terms for genes affiliated with Phobic Disorder

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Products for genes affiliated with Phobic Disorder

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Phobic Disorder

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet