MCID: PHY007
MIFTS: 26

Phyllode Tumor malady

Categories: Reproductive diseases, Cancer diseases, Rare diseases

Aliases & Classifications for Phyllode Tumor

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Sources:
51Orphanet, 65UMLS, 37MESH via Orphanet, 28ICD10 via Orphanet, 66UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Phyllode Tumor:

Name: Phyllode Tumor 51
Cystosarcoma Phylloide 51
Cystosarcoma Phyllode 51
 
Phyllodes Tumor 65
Phylloide Tumor 51

Characteristics:

Orphanet epidemiological data:

51
cystosarcoma phylloide:
Age of onset: Adult

Classifications:



External Ids:

Orphanet51 180261
MESH via Orphanet37 D003557
ICD10 via Orphanet28 D48.6
UMLS via Orphanet66 C0010701

Summaries for Phyllode Tumor

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MalaCards based summary: Phyllode Tumor, also known as cystosarcoma phylloide, is related to benign breast phyllodes tumor and breast malignant phyllodes tumor. Affiliated tissues include breast, prostate and brain.

Related Diseases for Phyllode Tumor

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Graphical network of the top 20 diseases related to Phyllode Tumor:



Diseases related to phyllode tumor

Symptoms for Phyllode Tumor

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Drugs & Therapeutics for Phyllode Tumor

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Drugs for Phyllode Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 8)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
FluorouracilapprovedPhase 1168451-21-83385
Synonyms:
1-fluoro-1h-pyrimidine-2,4-dione
1004-03-1
1upf
2,4-Dihydroxy-5-fluoropyrimidine
2,4-Dioxo-5-fluoropryimidine
2,4-Dioxo-5-fluoropyrimidine
47576_FLUKA
4921-97-5
5 FU Lederle
5 FU medac
5 Fluorouracil
5 Fluorouracil biosyn
5 HU Hexal
5-FU
5-FU (TN)
5-FU Lederle
5-FU medac
5-Faracil
5-Fluor-2,4(1H,3H)-pyrimidindion
5-Fluor-2,4(1H,3H)-pyrimidindion [Czech]
5-Fluor-2,4-dihydroxypyrimidin
5-Fluor-2,4-dihydroxypyrimidin [Czech]
5-Fluor-2,4-pyrimidindiol
5-Fluor-2,4-pyrimidindiol [Czech]
5-Fluoracil
5-Fluoracil [German]
5-Fluoracyl
5-Fluoro-2,4(1H,3H)-pyrimidinedione
5-Fluoro-2,4-pyrimidinedione
5-Fluoropyrimidin-2,4-diol
5-Fluoropyrimidine-2,4-dione
5-Fluorouracil
5-Fluorouracil-biosyn
5-Fluoruracil
5-Fluoruracil [German]
5-Fluracil
5-Ftouracyl
5-HU Hexal
5-fluoro uracil
5-fluoro-1H-pyrimidine-2,4-dione
5-fluoropyrimidine-2,4(1H,3H)-dione
5-fluorouracil
51-21-8
5FU
79108-01-3
AC-11201
AC1L1FTE
AC1Q4N2X
AI3-25297
AKOS000119162
AKOS003237897
AccuSite
Actino-Hermal
Adrucil
Adrucil (TN)
Allergan Brand of Fluorouracil
Arumel
BB_NC-0576
BSPBio_002048
C07649
C4H3FN2O2
CCRIS 2582
CHEBI:46345
CHEMBL185
CID3385
CPD0-1327
CPD000038082
CSP Brand of Fluorouracil
Carac
Carac (TN)
Carzonal
Cinco FU
Cytosafe
D005472
D00584
DB00544
Dakota Brand of Fluorouracil
Dakota, Fluorouracile
Dermatech Brand of Fluorouracil
Dermik Brand of Fluorouracil
DivK1c_000054
EINECS 200-085-6
EU-0100536
Effluderm
Effluderm (free base)
Efudex
Efudix
Efurix
F 6627
F0151
F6627_SIGMA
F8423_SIGMA
FT-0082524
FU
Ferrer Brand of Fluorouracil
Fiverocil
Fluoro Uracil
Fluoro Uracile ICN
Fluoro-Uracile ICN
Fluoro-uracile
Fluoro-uracilo
Fluoroblastin
Fluoroplex
Fluoroplex (TN)
Fluorouracil
Fluorouracil (JP15/USP/INN)
Fluorouracil GRY
Fluorouracil Mononitrate
Fluorouracil Monopotassium Salt
Fluorouracil Monosodium Salt
Fluorouracil Potassium Salt
Fluorouracil Teva Brand
Fluorouracil [USAN:INN:BAN:JAN]
 
Fluorouracil-GRY
Fluorouracile
Fluorouracile Dakota
Fluorouracile [DCIT]
Fluorouracilo
Fluorouracilo Ferrer Far
Fluorouracilo [INN-Spanish]
Fluorouracilum
Fluorouracilum [INN-Latin]
Fluoruracil
Fluouracil
Flurablastin
Fluracedyl
Fluracil
Fluracilum
Fluri
Fluril
Fluro Uracil
Fluroblastin
Flurodex
Flurouracil
Flurox
Ftoruracil
Gry Brand of Fluorouracil
HMS1920O18
HMS2090I04
HMS2091F19
HMS500C16
HSDB 3228
Haemato Brand of Fluorouracil
Haemato fu
Haemato-fu
Hexal Brand of Fluorouracil
I07-0022
ICN Brand of Fluorouracil
IDI1_000054
IN1335
KBio1_000054
KBio2_001321
KBio2_003889
KBio2_006457
KBio3_001268
KBioGR_001253
KBioSS_001321
Kecimeton
LS-153
Lopac-F-6627
Lopac0_000536
MLS000069498
MLS002415705
MolPort-000-156-102
MolPort-003-990-447
MolPort-004-758-143
MolPort-004-758-144
MolPort-005-861-486
NCGC00015442-01
NCGC00015442-03
NCGC00015442-10
NCGC00091349-01
NCGC00091349-02
NCGC00091349-03
NCGC00091349-04
NCGC00091349-05
NCGC00091349-07
NCGC00091349-08
NCI60_001652
NINDS_000054
NSC 19893
NSC-19893
NSC19893
Neocorp Brand of Fluorouracil
Neofluor
Onkofluor
Onkoworks Brand of Fluorouracil
Phthoruracil
Phtoruracil
Queroplex
Ribofluor
Riemser Brand of Fluorouracil
Ro 2-9757
Ro-2-9757
Roche Brand of Fluorouracil
S1209_Selleck
SAM002264615
SMR000038082
SPBio_000291
SPECTRUM1500305
STK297802
Spectrum2_000076
Spectrum3_000434
Spectrum4_000557
Spectrum5_000718
Spectrum_000841
T5233394
TL8006093
Teva Brand of Fluorouracil
Timazin
U 8953
U-8953
UNII-U3P01618RT
UPCMLD-DP130
UPCMLD-DP130:001
URF
Ulup
WLN: T6MVMVJ EF
ZINC00897110
biosyn Brand of Fluorouracil
fluorouracil
inhibits thymilidate synthetase
medac Brand of Fluorouracil
nchembio.90-comp3
nchembio809-comp6
ribosepharm Brand of Fluorouracil
tetratogen
2
Belinostatapproved, investigationalPhase 141
Synonyms:
Beleodaq
 
Belinostat
PXD 101
3Immunologic FactorsPhase 118483
4Immunosuppressive AgentsPhase 110422
5Histone Deacetylase InhibitorsPhase 1532
6AntimetabolitesPhase 19454
7AndrogensPhase 11162
8Antimetabolites, AntineoplasticPhase 15770

Interventional clinical trials:

idNameStatusNCT IDPhase
1Radiation Therapy After Surgery in Treating Women With Phyllodes Tumor of the BreastActive, not recruitingNCT00003404Phase 2
2Study of PXD101 Alone and in Combination With 5-Fluorouracil (5-FU) in Patients With Advanced Solid TumorsCompletedNCT00413322Phase 1
3Phyllodes Tumor Partial Breast Radiation StudyRecruitingNCT01089374

Search NIH Clinical Center for Phyllode Tumor

Genetic Tests for Phyllode Tumor

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Anatomical Context for Phyllode Tumor

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MalaCards organs/tissues related to Phyllode Tumor:

33
Breast, Prostate, Brain, Endothelial, Lung, Colon, Pineal

Animal Models for Phyllode Tumor or affiliated genes

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Publications for Phyllode Tumor

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Articles related to Phyllode Tumor:

(show top 50)    (show all 77)
idTitleAuthorsYear
1
C-kit overexpression correlates with KIT gene copy numbers increases in phyllodes tumors of the breast. (25534827)
2015
2
Mutational analysis of MED12 in fibroadenomas and phyllodes tumors of the breast by means of targeted next-generation sequencing. (26093648)
2015
3
Recurrent angio-fibroma of breast masquerading as phyllodes tumor. (26458623)
2015
4
CD117 expression in breast phyllodes tumors correlates with adverse pathologic parameters and reduced survival. (25216225)
2015
5
Distribution of MED12 mutations in fibroadenomas and phyllodes tumors of the breast--implications for tumor biology and pathological diagnosis. (25931199)
2015
6
Next-Gen Sequencing Exposes Frequent MED12 Mutations and Actionable Therapeutic Targets in Phyllodes Tumors. (25593300)
2015
7
Malignant phyllodes tumors display mesenchymal stem cell features and aldehyde dehydrogenase/disialoganglioside identify their tumor stem cells. (24670249)
2014
8
Nuclear survivin expression in stromal cells of phyllodes tumors and fibroadenomas of the breast. (24596368)
2014
9
Collision tumor with inflammatory breast carcinoma and malignant phyllodes tumor: a case report and literature review. (24400686)
2014
10
Phyllodes tumor of the breast: role of Axl and ST6GalNAcII in the development of mammary phyllodes tumors. (24961352)
2014
11
The expression of glutamine-metabolism-related proteins in breast phyllodes tumors. (23636801)
2013
12
Ubiquitin carboxy-terminal hydrolase L1 may be involved in the development of mammary phyllodes tumors. (23291960)
2013
13
Severe hypoglycemia with "Big"-IGF-2 oversecretion by a giant phyllode tumor of the breast: a rare case of non-islet cell tumor-induced hypoglycemia (NICTH). (22867750)
2012
14
ER, p53 and MIB-1 are significantly associated with malignant phyllodes tumor. (23442362)
2012
15
Phyllodes tumor of the breast: role of CD10 in predicting metastasis. (22006372)
2012
16
Invasive cribriform carcinoma arising in malignant phyllodes tumor of breast: a case report. (23110003)
2012
17
Hormone receptors expression in phyllodes tumors of the breast. (22590818)
2012
18
Jejunal intussusception due to malignant phyllodes tumor of the breast. (22381472)
2012
19
E-cadherin expression in the epithelial components of mammary phyllodes tumors. (22820000)
2012
20
Keratin 15, transcobalamin I and homeobox gene Hox-B13 expression in breast phyllodes tumors: novel markers in biological classification. (21574054)
2012
21
Ductal carcinoma in situ arising within a benign phyllodes tumor: A case report with a review of the literature. (22866068)
2011
22
A case of a giant phyllodes tumor of the breast with hypoglycemia caused by high-molecular-weight insulin-like growth factor II. (19259766)
2010
23
c-Kit expression and mutations in phyllodes tumors of the breast. (21115932)
2010
24
Fibroadenoma and phyllodes tumors of anogenital mammary-like glands: a series of 13 neoplasms in 12 cases, including mammary-type juvenile fibroadenoma, fibroadenoma with lactation changes, and neurofibromatosis-associated pseudoangiomatous stromal hyperplasia with multinucleated giant cells. (20035149)
2010
25
Expression of anaphase-promoting complex7 in fibroadenomas and phyllodes tumors of breast. (18789487)
2009
26
Molecular pathogenesis of progression and recurrence in breast phyllodes tumors. (19966935)
2009
27
An approach to malignant mammary phyllodes tumors detection. (19441158)
2009
28
Beta-human chorionic gonadotropin production associated with phyllodes tumor of the breast: an unusual paraneoplastic phenomenon. (19624411)
2009
29
Benign phyllodes tumor of the breast with intracytoplasmic inclusion bodies identical to infantile digital fibromatosis. (18266786)
2008
30
Association of the BRCA1 missense variant R1699W with a malignant phyllodes tumor of the breast. (17574969)
2007
31
Hypoglycemic coma secondary to big insulin-like growth factor II secretion by a giant phyllodes tumor of the breast. (17319862)
2007
32
Malignant phyllode tumor metastatic to the duodenum. (16570365)
2006
33
Phyllodes tumor: a clinicopathologic and immunohistochemical study of 30 cases. (17090194)
2006
34
CD10, actin, and vimentin expression in breast phyllodes tumors correlates with tumor grades of the WHO grading system. (16703173)
2006
35
Estrogen receptor-beta is expressed in stromal cells of fibroadenoma and phyllodes tumors of the breast. (16554735)
2006
36
p53 and c-kit (CD117) protein expression as prognostic indicators in breast phyllodes tumors: a tissue microarray study. (16258510)
2005
37
Progressive deregulation of the cell cycle with higher tumor grade in the stroma of breast phyllodes tumors. (15981808)
2005
38
Increased c-kit (CD117) expression in malignant mammary phyllodes tumors. (15044924)
2004
39
Phyllodes tumor of the prostate: long-term followup study of 23 cases. (15310992)
2004
40
An immunohistochemical study of metaplastic spindle cell carcinoma, phyllodes tumor and fibromatosis of the breast. (14608534)
2003
41
Phyllodes tumor metastatic to thyroid HA1rthle cell adenoma. (12296767)
2002
42
Proliferating activity in differential diagnosis of benign phyllodes tumor and cellular fibroadenomas: is it helpful? (11692149)
2001
43
Prognostic evaluation of proliferative activity and DNA content in the phyllodes tumor of the breast: immunohistochemical and flow cytometric study of 118 cases. (11245343)
2001
44
Platelet-derived growth factor expression in phyllodes tumors and fibroadenomas of the breast. (11070114)
2000
45
Malignant phyllodes tumor of the breast with hypoglycemia: report of a case. (9657015)
1998
46
Progression of fibroadenoma to phyllodes tumor demonstrated by clonal analysis. (8625047)
1995
47
Phyllodes tumor of the breast containing the intracytoplasmic inclusion bodies identical with infantile digital fibromatosis. (8172324)
1994
48
Phyllode tumor of the breast: mammographic experience in 99 cases. (1327792)
1992
49
50

Variations for Phyllode Tumor

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Expression for genes affiliated with Phyllode Tumor

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Search GEO for disease gene expression data for Phyllode Tumor.

Pathways for genes affiliated with Phyllode Tumor

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GO Terms for genes affiliated with Phyllode Tumor

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Sources for Phyllode Tumor

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet