MCID: PLC011
MIFTS: 58

Pilocytic Astrocytoma malady

Categories: Rare diseases, Neuronal diseases, Cancer diseases

Aliases & Classifications for Pilocytic Astrocytoma

About this section
Sources:
11Disease Ontology, 13DISEASES, 27GTR, 31ICD10 via Orphanet, 39MeSH, 45NCIt, 48NIH Rare Diseases, 50Novoseek, 54Orphanet, 62SNOMED-CT, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Pilocytic Astrocytoma:

Name: Pilocytic Astrocytoma 11 48 54 27 50 13 68
Juvenile Pilocytic Astrocytoma 48 68
 
Grade I Astrocytic Tumor 11
Piloid Astrocytoma 11

Characteristics:

Orphanet epidemiological data:

54
pilocytic astrocytoma:
Inheritance: Not applicable; Age of onset: All ages

Classifications:



External Ids:

Disease Ontology11 DOID:4851
MeSH39 D001254
NCIt45 C4047
Orphanet54 ORPHA251612
UMLS via Orphanet69 C0334583
ICD10 via Orphanet31 C79.1

Summaries for Pilocytic Astrocytoma

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NIH Rare Diseases:48 Pilocytic astrocytoma is an often benign, slow-growing tumor of the brain or spinal cord. The tumor may be in the form of a cyst and usually does not spread to nearby tissues. Symptoms vary depending upon the size and location of the tumor. Most symptoms result from increased pressure on the brain and include headaches, nausea, vomiting, balance problems, and vision abnormalities. The underlying cause of a pilocytic astrocytoma is unknown. It most commonly occurs in children and young adults, and in people with neurofibromatosis type 1 (NF1), Li-Fraumeni syndrome, and tuberous sclerosis. This type of tumor can often be cured with surgery. Last updated: 8/9/2013

MalaCards based summary: Pilocytic Astrocytoma, also known as juvenile pilocytic astrocytoma, is related to ganglioglioma and pleomorphic xanthoastrocytoma, and has symptoms including headache, headache and headache. An important gene associated with Pilocytic Astrocytoma is KIAA1549 (KIAA1549), and among its related pathways are pilocytic astrocytoma and p38MAPK events. Affiliated tissues include the brain, brain and spinal cord, and related mouse phenotypes are Increased senescence-associated beta-galactosidase protein expression after pRB stimulation and Decreased human cytomegalovirus (HCMV) strain AD169 replication.

Disease Ontology:11 An astrocytoma that is characterized by cells that look like fibers when viewed under a microscope and is located in the brain.

Wikipedia:71 Pilocytic astrocytoma or juvenile pilocytic astrocytoma or cystic cerebellar astrocytoma (and its... more...

Related Diseases for Pilocytic Astrocytoma

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Diseases in the Pilocytic Astrocytoma family:

Juvenile Pilocytic Astrocytoma

Diseases related to Pilocytic Astrocytoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 167)
idRelated DiseaseScoreTop Affiliating Genes
1ganglioglioma31.2GFAP, IDH1, KIAA1549
2pleomorphic xanthoastrocytoma30.7BRAF, IDH1, KIAA1549, NF1
3pilocytic astrocytoma of cerebellum30.6BRAF, CDKN2A, ERBB3, FGFR1, GFAP, HRAS
4juvenile pilocytic astrocytoma12.3
5childhood pilocytic astrocytoma12.2
6astrocytoma11.1
7karak syndrome10.8BRAF, CDKN2A
8glomeruloid hemangioma10.8GFAP, NF1
9otof-related deafness10.8BRAF, PTPN11, RAF1
10vagina sarcoma10.8HRAS, KRAS
11pulmonary venoocclusive disease10.8BRAF, GFAP, KRAS
12leukoencephalopathy palmoplantar keratoderma10.8BRAF, CDKN2A, KRAS
13split hand split foot malformation autosomal recessive10.8BRAF, CDKN2A, HRAS
14neonatal stroke10.7HRAS, NF1, PTPN11
15intrahepatic bile duct cystadenoma10.7GFAP, IDH1, KIAA1549
16hypoglossal nerve neoplasm10.7CDKN2A, NF1, SOX10
17compartment syndrome10.7CDKN2A, GFAP, NF1
18gliofibroma10.7BRAF, IDH1, KIAA1549, NF1
19early myoclonic encephalopathy10.7CDKN2A, GFAP, IDH1
20glomerulosclerosis10.7HRAS, KRAS
21ureter adenocarcinoma10.7CDKN2A, HRAS, KRAS
22spindle epithelial tumor with thymus-like differentiation tumor10.7CDKN2A, HRAS, KRAS
23schwannoma of twelfth cranial nerve10.7GFAP, NF1, SOX10
24adenofibroma10.7CDKN2A, HRAS, KRAS
25angiokeratoma circumscriptum10.7CDKN2A, NF1, SOX10
26tuberculous empyema10.7BRAF, NF1, PTPN11, RAF1
27growth restriction, severe, with distinctive facies10.7HRAS, KRAS, PTPN11
28pterygium colli mental retardation digital anomalies10.7BRAF, KRAS, PTPN11, RAF1
29rad51c-related fanconi anemia10.7BRAF, KRAS, PTPN11, RAF1
30mantle cell lymphoma10.7CDKN2A, GFAP, IDH1
31pancreatoblastoma10.7NF1, PBX3
32gastrointestinal neuroendocrine tumor10.7CDKN2A, HRAS, KRAS
33hemangioma of lung10.7HRAS, IDH1, KRAS
34arteritic anterior ischemic optic neuropathy10.7BRAF, HRAS, KRAS
35gonococcal spondylitis10.7HRAS, KRAS
36pancreatic somatostatinoma10.6CDKN2A, HRAS, KRAS
37trachea adenoid cystic carcinoma10.6HRAS, KRAS, NFIB
38dubin-johnson syndrome10.6BRAF, CDKN2A, HRAS
39nasopharyngeal carcinoma10.6CDKN2A, IDH1, NF1
40trachea sarcoma10.6CDKN2A, HRAS, KRAS
41growth hormone insensitivity with immunodeficiency10.6NF1, PTPN11
42multiple mucosal neuroma10.6CDKN2A, GFAP, NF1, SOX10
43leukemia, acute myelomonocytic, somatic, somatic10.6HRAS, KRAS, NF1, PTPN11
44atrial standstill10.6BRAF, HRAS, KRAS
452q33.1 microdeletion syndrome10.6BRAF, SYP
46epidermal nevus, somatic10.6HRAS, KRAS
47hartnup disorder10.6CDKN2A, HRAS, KRAS
48paroxysmal nocturnal hemoglobinuria10.6CDKN2A, HRAS, KRAS
49schimmelpenning-feuerstein-mims syndrome, somatic mosaic10.6HRAS, KRAS
50gallbladder papillomatosis10.6CDKN2A, HRAS, KRAS

Graphical network of the top 20 diseases related to Pilocytic Astrocytoma:



Diseases related to pilocytic astrocytoma

Symptoms & Phenotypes for Pilocytic Astrocytoma

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UMLS symptoms related to Pilocytic Astrocytoma:


headache

GenomeRNAi Phenotypes related to Pilocytic Astrocytoma according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00230-A-210.8ERBB3, NTRK2, RAF1
2GR00248-A10.5BRAF, ERBB3, FGFR1, NTRK2, RAF1
3GR00055-A-110.4BRAF, HRAS, KRAS, NF1, SRGAP3
4GR00055-A-310.4BRAF, HRAS, KRAS, NF1, SRGAP3
5GR00366-A-359.8BRAF, FGFR1, IDH1, PTPN11, SRGAP3
6GR00235-A9.2APOD, BRAF, CDKN2A, GFAP, HRAS, IDH1
7GR00381-A-17.7CDKN2A, FGFR1, HRAS, KRAS, NF1, NTRK2

MGI Mouse Phenotypes related to Pilocytic Astrocytoma according to GeneCards Suite gene sharing:

41 (show all 22)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000537010.0BRAF, CDKN2A, KRAS, NF1, NTRK2, PTPN11
2MP:000537710.0APOD, BRAF, FGFR1, KRAS, NF1, NTRK2
3MP:00011869.9BRAF, CDKN2A, ERBB3, KRAS, NF1, PTPN11
4MP:00053759.8BRAF, KIAA1549, NTRK2, OLIG2, PBX3, PTPN11
5MP:00053809.7BRAF, CDKN2A, ERBB3, FGFR1, KRAS, NF1
6MP:00053829.5BRAF, FGFR1, HRAS, KRAS, NF1, NFIB
7MP:00053699.5BRAF, CDKN2A, ERBB3, FGFR1, GFAP, KRAS
8MP:00020069.4BRAF, CDKN2A, ERBB3, HRAS, KRAS, NF1
9MP:00053919.3BRAF, CDKN2A, FGFR1, GFAP, KRAS, NF1
10MP:00107719.2BRAF, CDKN2A, ERBB3, FGFR1, HRAS, KRAS
11MP:00053909.1BRAF, CDKN2A, FGFR1, HRAS, IDH1, KRAS
12MP:00053799.1BRAF, CDKN2A, ERBB3, FGFR1, HRAS, KRAS
13MP:00028739.0BRAF, ERBB3, FGFR1, GFAP, HRAS, KRAS
14MP:00053819.0BRAF, CDKN2A, ERBB3, FGFR1, GFAP, KRAS
15MP:00053849.0BRAF, CDKN2A, ERBB3, FGFR1, GFAP, KRAS
16MP:00053858.9APOD, BRAF, CDKN2A, ERBB3, FGFR1, GFAP
17MP:00053888.7BRAF, CDKN2A, ERBB3, HRAS, IDH1, KRAS
18MP:00053788.3BRAF, CDKN2A, ERBB3, FGFR1, GFAP, HRAS
19MP:00053868.1APOD, BRAF, CDKN2A, ERBB3, FGFR1, GFAP
20MP:00053768.1APOD, BRAF, CDKN2A, ERBB3, FGFR1, GFAP
21MP:00107688.0APOD, BRAF, CDKN2A, ERBB3, FGFR1, GFAP
22MP:00036317.9APOD, BRAF, CDKN2A, ERBB3, FGFR1, GFAP

Drugs & Therapeutics for Pilocytic Astrocytoma

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Drugs for Pilocytic Astrocytoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 162)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
DonepezilapprovedPhase 3, Phase 2280120014-06-43152
Synonyms:
( inverted exclamation markA)-E 2020
1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine
120014-06-4
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one
AB1004836
AC-6969
AC1L1FAE
AKOS000277311
Aricept
Aricept ODT
C24H29NO3
CHEBI:53289
CHEMBL502
CID3152
D07869
DB00843
Domepezil
Donaz
Donaz (TN)
 
Donepezil
Donepezil (INN)
Donepezil [INN:BAN]
Donepezil hydrochloride
Donepezilo
Donepezilum
Eranz
I06-0343
KBio2_002144
KBio2_004712
KBio2_007280
KBioSS_002144
LS-81819
MolPort-000-881-588
MolPort-003-847-014
NCGC00167537-01
Oprea1_188452
Spectrum5_001662
Spectrum_001664
TL8000531
UNII-8SSC91326P
2
Fentanylapproved, illicit, investigational, vet_approvedPhase 3773437-38-73345
Synonyms:
1-Phenethyl-4-(N-phenylpropionamido)piperidine
1-Phenethyl-4-N-propionylanilinopiperidine
1-phenethyl-4-N-propionylanilinopiperidine
437-38-7
5-22-08-00049 (Beilstein Handbook Reference)
80832-90-2
990-73-8 (citrate)
AC1L1FQ2
Actiq
BIDD:GT0555
BRN 0494484
CHEBI:119915
CHEMBL596
CID3345
D00320
DB00813
Duragesic
Duragesic (TN)
Duragesic-100
Duragesic-12
Duragesic-25
Duragesic-50
Duragesic-75
Durogesic
EINECS 207-113-6
Fentanest
Fentanil
Fentanil [DCIT]
Fentanila
Fentanila [INN-Spanish]
Fentanilo
Fentanyl
Fentanyl (JAN/USAN/INN)
Fentanyl CII
Fentanyl [INN:BAN]
Fentanyl citrate
Fentanyl-100
Fentanyl-12
Fentanyl-25
 
Fentanyl-50
Fentanyl-75
Fentanylum
Fentanylum [INN-Latin]
HSDB 3329
IONSYS
JNS020QD
L001275
LS-124439
Matrifen
MolPort-003-847-369
N-(1-Phenethyl-4-piperidinyl)-N-phenylpropionamide
N-(1-Phenethyl-4-piperidyl)propionanilide
N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide
N-(1-Phenethylpiperidin-4-yl)-N-phenylpropionamide
N-(1-phenethyl-4-piperidinyl)-N-phenylpropionamide
N-(1-phenethyl-4-piperidyl)propionanilide
N-(1-phenethylpiperidin-4-yl)-N-phenylpropanamide
N-(1-phenethylpiperidin-4-yl)-N-phenylpropionamide
N-Phenethyl-4-(N-propionylanilino)piperidine
N-Phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide
N-phenethyl-4-(N-propionylanilino)piperidine
N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide
N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide
NCGC00168252-01
Nasalfent
Oprea1_152073
Oprea1_207148
PDSP1_000860
PDSP2_000846
Pentanyl
Phentanyl
Propanamide, N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)- (9CI)
R 4263
Rapinyl
Sentonil
Sublimase
Sublimaze
UNII-UF599785JZ
fentanyl
3
Vincristineapproved, investigationalPhase 2, Phase 3, Phase 19042068-78-2, 57-22-75978
Synonyms:
22-Oxovincaleukoblastin
22-Oxovincaleukoblastine
28379-27-3
57-22-7
AC1L1LJC
C07204
C46H56N4O10
CCRIS 5763
CHEBI:28445
CID5978
D08679
DB00541
EINECS 200-318-1
HMS2090E19
HSDB 3199
Indole alkaloid
LCR
LS-228
Leurocristine
Lilly 37231 (1:1 sulfate salt)
Liposomal Vincristine
Marqibo
NCGC00163700-01
NCI-C04864
NCI60_026703
NSC-67574
Onco TCS
 
Oncovin
Oncovin (1:1 sulfate salt)
Oncovine
Tecnocris
Tecnocris (TN)
UNII-5J49Q6B70F
VCR
VIN
Vincaleukoblastine, 22-oxo- 22-Oxovincaleukoblastine
Vincasar
Vincasar (1:1 sulfate salt)
Vincasar PFS
Vincrex
Vincrex (1:1 sulfate salt)
Vincristin
Vincristina
Vincristina [DCIT]
Vincristine (INN)
Vincristine Sulfate
Vincristine Sulfate PFS
Vincristine [INN:BAN]
Vincristinum
Vincristinum [INN-Latin]
Vincrstine
Vincrystine
Vinkristin
Z-D-Val-Lys(Z)-OH
vincristine
4
DopamineapprovedPhase 3375951-61-6, 62-31-7681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
KBio1_000780
 
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
5
ProcarbazineapprovedPhase 2, Phase 369671-16-94915
Synonyms:
1-Methyl-2-(p-(isopropylcarbamoyl)benzyl)hydrazine
2-(p-Isopropylcarbamoylbenzyl)-1-methylhydrazine
366-70-1 (mono-hydrochloride)
4-((2-Methylhydrazino)methyl)-N-isopropylbenzamide
4-[(2-methylhydrazinyl)methyl]-N-propan-2-ylbenzamide
671-16-9
AC-4547
AC1L1J8E
Ambap671-16-9
BIDD:GT0183
BPBio1_001369
BRN 0958270
BSPBio_001244
Benzamide, N-(1-methylethyl)-4-((2-methylhydrazino)methyl)- (9CI)
C07402
C12H19N3O
CAS-366-70-1
CB 400-497
CCRIS 2389
CHEMBL1321
CID4915
D08423
DB01168
EINECS 211-582-2
HMS2090J09
HSDB 3250
I01-8931
IBZ
Ibenzmethyzin
Ibenzmethyzine
LS-7671
MBH
MIH
MolPort-005-940-370
N-(1-Methylethyl)-4-((2-methylhydrazino)methyl)benzamide
 
N-(1-Methylethyl)-4-[(2-methylhydrazino)methyl]benzamide
N-4-Isopropylcarbamoylbenzyl-N'-methylhydrazine
N-Isopropyl-4-[(2-methylhydrazino)methyl]benzamide
N-Isopropyl-alpha-(2-methylhydrazino)-p-toluamide
N-Isopropyl-p-(2-methylhydrazinomethyl)-benzamide
N-Isopropyl-α-(2-methylhydrazino)-p-toluamide
N-isopropyl-4-[(2-methylhydrazino)methyl]benzamide
NCGC00016438-01
NCGC00016438-02
NCI60_041703
NCIOpen2_004074
NSC-77213
Natulan
Natulanar
PCX
Prestwick0_001112
Prestwick1_001112
Prestwick2_001112
Prestwick3_001112
Procarbazin
Procarbazin [German]
Procarbazina
Procarbazina [INN-Spanish]
Procarbazine (INN)
Procarbazine Monohydrochloride
Procarbazine [INN:BAN]
Procarbazinum
Procarbazinum [INN-Latin]
Ro 4-6467
Ro 4-6467/1
SPBio_003112
SRI-10847
UNII-35S93Y190K
p-(2-Methylhydrazinomethyl)-N-isopropylbenzamide
p-(N'-Methylhydrazinomethyl)-N-isopropylbenzamide
procarbazine
6
LomustineapprovedPhase 2, Phase 38213010-47-43950
Synonyms:
(Chloro-2-ethyl)-1-cyclohexyl-3-nitrosourea
(Cloro-2-etil)-1-cicloesil-3-nitrosourea
(Cloro-2-etil)-1-cicloesil-3-nitrosourea [Italian]
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea [Chloroethyl nitrosoureas]
1-(2-Chloroethyl)-3-cyclohexylnitrosourea
13010-47-4
AC-10564
AC1L1H2T
AI3-52779
BRN 2125058
Belustine
Bristol Myers Squibb Brand of Lomustine
Bristol-Myers Squibb Brand of Lomustine
C9H16ClN3O2
CCNU
CCNU [Chloroethyl nitrosoureas]
CCRIS 860
CHEMBL514
CID3950
CINU
Cecenu
CeeNU
CeeNU (TN)
CeeNU, CCNU, Lomustine
Chloroethylcyclohexylnitrosourea
Cyclohexyl chloroethyl nitrosourea
D00363
D008130
DB01206
EINECS 235-859-2
FT-0083566
 
HMS2090A17
HSDB 6519
I06-0087
ICIG 1109
LS-728
Lomustina
Lomustina [INN-Spanish]
Lomustine (USAN/INN)
Lomustine [USAN:BAN:INN]
Lomustine medac Brand
Lomustinum
Lomustinum [INN-Latin]
MolPort-001-768-818
N-(2-Chloroethyl)-N'-cyclohexyl-N-nitrosourea
N-(2-Chloroethyl)-n'-cyclohexyl-N-nitrosourea
NCGC00167466-01
NCI-C04740
NCI60_041743
NCIMech_000220
NPFAPI-06
NSC 79037
NSC-79037
NSC79037
OR5087
RB 1509
Rhone Poulenc Rorer Brand of Lomustine
Rhone-Poulenc Rorer Brand of Lomustine
S1840_Selleck
SRI 2200
UNII-7BRF0Z81KG
WLN: L6TJ AMVNNO&2G
ZINC03831006
lomustine
medac Brand of Lomustine
7
HistamineapprovedPhase 3103475614-87-8, 51-45-6774
Synonyms:
.beta.-Imidazolyl-4-ethylamine
1H-Imidazole-4-ethanamine
1H-Imidazole-5-ethanamine
1avn
1qft
2-(1H-Imidazol-4-yl)ethanamine
2-(1H-Imidazol-4-yl)ethylamine
2-(1H-Imidazol-5-yl)ethanamine
2-(1H-Imidazol-5-yl)ethylamine
2-(1H-imidazol-4-yl)ethan-1-amine
2-(1H-imidazol-5-yl)ethanamine
2-(3H-Imidazol-4-yl)-ethylamine
2-(4-Imidazolyl)ethanamine
2-(4-Imidazolyl)ethylamine
2-Imidazol-4-yl-Ethylamine
2-Imidazol-4-ylethylamine
2-[4-Imidazolyl]ethylamine
4-(2-Aminoethyl)-1H-imidazole
4-(2-Aminoethyl)imidazole
4-Imidazoleethylamine
5-Imidazoleethylamine
51-45-6
53290_FLUKA
64422-25-9
924364-91-0
AC-13185
AC1L19ZT
AC1Q54BV
AC1Q54BW
AKOS000274386
ALBB-005968
BCBcMAP01_000250
BSPBio_001117
BSPBio_002124
Bio1_000487
Bio1_000976
Bio1_001465
Bio2_000389
Bio2_000869
C00388
CCRIS 6535
CHEBI:18295
CHEMBL90
CID774
D08040
DivK1c_000308
EINECS 200-100-6
Eramin
Ergamine
Ergotidine
F411C768-A159-4FC0-A195-291A08BB03AA
Free histamine
H7125_SIGMA
HMS1362G19
HMS1792G19
HMS1990G19
HSDB 3338
HSM
Histamine
Histamine (DCF)
Histamine Base
Histamine [USAN]
Histamine, Free Base
Histaminum
 
Histaminum (TN)
IDI1_000308
IDI1_002144
Imidazole-4-ethylamine
Istamina
Istamina [Italian]
KBio1_000308
KBio2_000457
KBio2_001325
KBio2_003025
KBio2_003893
KBio2_005593
KBio2_006461
KBio3_000853
KBio3_000854
KBio3_001344
KBioGR_000457
KBioGR_001580
KBioSS_000457
KBioSS_001325
L-Histamin base
L-Histamine
L-histamine
L000292
LS-75835
Lopac-H-7250
Lopac0_000595
MLS000069447
MolPort-001-785-597
MolPort-002-042-264
NCGC00015513-01
NCGC00015513-08
NCGC00093371-02
NCGC00093371-03
NCGC00093371-04
NCGC00093371-05
NINDS_000308
NSC 33792
NSC33792
SDCCGMLS-0066601.P001
SMP1_000151
SMR000059091
SPBio_000729
ST073926
STK346752
STOCK5S-55669
Spectrum2_000665
Spectrum3_000452
Spectrum4_000960
Spectrum5_000796
Spectrum_000845
Theramine
UNII-820484N8I3
WLN: T5M CNJ D2Z
ZERO/004089
[3H]histamine
b-Imidazolyl-4-ethylamine
beta-Aminoethylglyoxaline
beta-Aminoethylimidazole
beta-Aminothethylglyoxaline
beta-Imidazolyl-4-ethylamine
beta-aminothethylglyoxaline
bmse000744
histamine
nchembio.87-comp54
nchembio714-comp1
8
Methylphenidateapproved, investigationalPhase 3373113-45-14158
Synonyms:
.alpha.-Phenyl-2-piperidineacetic acid methyl ester
113-45-1
2-Piperidineacetic acid, .alpha.-phenyl-, methyl ester
2-Piperidineacetic acid, alpha-phenyl-, methyl ester
298-59-9 (hydrochloride)
4311/B Ciba
AC1L1HJM
C 4311
C07196
CHEBI:6887
CHEMBL796
CID4158
Calocain
Centedein
Centedrin
Centedrine
Centredin
Concerta
D-Methylphenidate HCl
D04999
DB00422
DB06701
DEA No. 1724
Daytrana
Daytrana (TN)
EINECS 204-028-6
Focalin
Focalin XR
HSDB 3126
L001307
LS-565
METHYLPHENIDATE (SEE ALSO: METHYLPHENIDATE HYDROCHLORIDE, CAS 298-59-9, NTPNO 10266-R)
MPH
Meridil
Metadate
Metadate CD
Metadate ER
MethyPatch
Methyl (2-phenyl-2-(2-piperidyl)acetate)
Methyl alpha-phenyl-alpha-(2-piperidyl)acetate
Methyl alpha-phenyl-alpha-2-piperidinylacetate
Methyl phenidate
 
Methyl phenidyl acetate
Methyl phenidylacetate
Methylfenidan
Methylin
Methylin ER
Methylofenidan
Methylphen
Methylphenidan
Methylphenidate
Methylphenidate (USAN/INN)
Methylphenidate HCl
Methylphenidate [INN:BAN]
Methylphenidate hydrochloride
Methylphenidatum
Methylphenidatum [INN-Latin]
Methylphenidylacetate hydrochloride
Methypatch
Metilfenidat hydrochloride
Metilfenidato
Metilfenidato [INN-Spanish]
Metilfenidato [Italian]
MolPort-001-779-620
NCI-C56280
PMS-Methylphenidate
Phenidylate
Plimasine
Riphenidate
Ritalin
Ritalin LA
Ritalin SR
Ritalin hydrochloride
Ritalin-SR
Ritaline
Ritcher Works
Ritcher works
Tsentedrin
UNII-207ZZ9QZ49
alpha-Phenyl-2-piperidineacetic acid methyl ester
alpha-Phenyl-alpha-(2-piperidyl)acetic acid methyl ester
d-methylphenidate HCl
methyl 2-phenyl-2-piperidin-2-ylacetate
methyl phenyl(piperidin-2-yl)acetate
methylphenidate
nchembio.2007.55-comp28
9
Histamine PhosphateapprovedPhase 3103351-74-165513
Synonyms:
1H-Imidazole-4-ethanamine, phosphate (1:2)
2-Imidazol-4-ylethylamine orthophosphoric acid (1:2)
4-(2-Aminoethyl)imidazole bis(dihydrogen phosphate)
4-(2-Aminoethyl)imidazole di-acid phosphate
4-2(2-Aminoethyl)Imidazole-Di-Acid Phosphate
51-74-1
53623-99-7
74-56-6
AC1L23E4
CID65513
D04445
DB00667
 
EINECS 200-118-4
H0147
Histamine acid phosphate
Histamine biphosphate
Histamine dihydrogen phosphate
Histamine diphosphate
Histamine phosphate (1:2)
Histamine phosphate (TN)
Histamine phosphate (USP)
Histamine phosphate [USP]
Histamine positive
Histaminum
LS-78569
UNII-QWB37T4WZZ
10
CyproheptadineapprovedPhase 320129-03-32913
Synonyms:
1-Methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine
1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)piperidine
1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine
129-03-3
4-(5-Dibenzo(a,D)cyclohepten-5-ylidine)-1-methylpiperidine
4-(5-Dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine
4-(5H-Dibenzo(a,D)cyclohepten-5-ylidene)-1-methylpiperidine
4-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidene
4-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine
4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine
4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine
4-Dibenzo[a,D]cyclohepten-5-ylidene-1-methyl-piperidine
41354-29-4
5-(1-Methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene
5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene
5-20-08-00500 (Beilstein Handbook Reference)
AC1L1ER8
AKOS004119847
Axoprol
BIDD:GT0324
BPBio1_000096
BPBio1_000155
BRD-K28143534-001-01-4
BRD-K28143534-003-03-6
BRN 1685976
BSPBio_000086
Biomol-NT_000131
C06935
CAS-969-33-5
CCRIS 5232
CHEBI:4046
CHEMBL516
CID2913
CYPROHEPTADINE
Ciproheptadina
Ciproheptadina [INN-Spanish]
Ciprovit
Ciprovit (TN)
Cypoheptadine
Cyproheptadiene
Cyproheptadin
Cyproheptadine
 
Cyproheptadine (INN)
Cyproheptadine Hcl
Cyproheptadine [INN:BAN]
Cyproheptadinum
Cyproheptadinum [INN-Latin]
D07765
DB00434
Dibenzosuberonone/Cyproheptadine
Dihexazin
Dronactin
EINECS 204-928-9
Eiproheptadine
Glutodina
HMS2090P20
HSDB 3048
L001016
LS-114933
Lopac-C-6022
Lopac0_000246
MK 141
MolPort-002-507-777
NCGC00015252-01
NCGC00015252-02
NCGC00015252-03
NCGC00015252-09
NCGC00024293-02
NCGC00024293-04
NCGC00024293-05
Oprea1_498140
PDSP1_001229
PDSP2_001213
Periactin
Periactine
Periactinol
Prestwick0_000103
Prestwick1_000103
Prestwick2_000103
Prestwick3_000103
SPBio_002025
STK802098
Tocris-0996
UNII-2YHB6175DO
Viternum
nchembio.559-comp10
11Dermatologic AgentsPhase 3, Phase 2, Phase 15674
12AnalgesicsPhase 311287
13Anesthetics, IntravenousPhase 32406
14Central Nervous System DepressantsPhase 312806
15Central Nervous System StimulantsPhase 3, Phase 22132
16Gastrointestinal AgentsPhase 3, Phase 18109
17Analgesics, OpioidPhase 33091
18AnestheticsPhase 39001
19NarcoticsPhase 33486
20Anesthetics, GeneralPhase 32787
21Antineoplastic Agents, PhytogenicPhase 2, Phase 3, Phase 1, Early Phase 15420
22Adjuvants, AnesthesiaPhase 31588
23Cholinesterase InhibitorsPhase 3, Phase 2570
24Liver ExtractsPhase 3, Phase 2, Phase 13868
25Cholinergic AgentsPhase 3, Phase 23846
26Peripheral Nervous System AgentsPhase 322776
27pancreatic polypeptidePhase 3, Phase 120
28Antineoplastic Agents, AlkylatingPhase 2, Phase 3, Phase 14474
29Neurotransmitter AgentsPhase 3, Phase 217734
30Antimitotic AgentsPhase 2, Phase 3, Phase 15498
31Nootropic AgentsPhase 3, Phase 2701
32Alkylating AgentsPhase 2, Phase 3, Phase 14694
33Dopamine AgentsPhase 33759
34Dexmethylphenidate HydrochloridePhase 316
35Neurotransmitter Uptake InhibitorsPhase 33464
36Dopamine Uptake InhibitorsPhase 31305
37Histamine H1 AntagonistsPhase 3782
38AntipruriticsPhase 3864
39Serotonin AntagonistsPhase 31381
40Histamine AntagonistsPhase 3946
41Anti-Allergic AgentsPhase 31490
42
SerotoninPhase 3356650-67-95202
Synonyms:
3-(2-Aminoethyl)-1H-indol-5-ol
3-(2-Aminoethyl)indol-5-ol
3-(b-Aminoethyl)-5-hydroxyindole
5-HT
5-HTA
5-Hydroxy-3-(b-aminoethyl)indole
 
5-Hydroxy-tryptamine
5-Hydroxyltryptamine
5-Hydroxytriptamine
5-Hydroxytryptamine
Antemovis
DS substance
Enteramin
Enteramine
43Serotonin AgentsPhase 33102
44ColaNutraceuticalPhase 3, Phase 11881
45
TrioxsalenapprovedPhase 2, Phase 1413902-71-45585
Synonyms:
2',4,8-Trimethylpsoralen
4,5',8-Trimethylpsoralen
4,8,5'-Trimethylpsoralen
6-Hydroxy-beta,2,7-trimethyl-5-benzofuranacrylic acid, delta-lactone
Trimethylpsoralen
Trioxisaleno
 
Trioxsalen
Trioxysalen
Trioxysalene
Trioxysalenum
Trisoralen
trimethylpsoralen
trioxysalen
trisoralen
46
TamoxifenapprovedPhase 238010540-29-12733526
Synonyms:
(Z)-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene
(Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine
(Z)-2-(4-(1,2-diphenylbut-1-enyl)phenoxy)-N,N-dimethylethanamine
(Z)-2-(Para-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine
(Z)-2-(para-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine (IUPAC)
(Z)-2-[4-(1,2)-DIPHENYL-1-BUTENYL)-PHENOXY]-N,N-DIMETHYLETHANAMINE
(Z)-2-[p-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine
,citrate
1-P-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene
1-Para-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene
1-p-.beta.-Dimethylamino-ethoxyphenyl-trans-1,2-diphenylbut-1-ene
1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene
1-para-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene
10540-29-1
1ya4
2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine
2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine
54965-24-1 (citrate)
AC1MBZ3R
Apo-Tamox
Apo-tamox
BIDD:ER0008
BIDD:GT0009
BIDD:PXR0003
BPBio1_000278
BRD-K93754473-001-02-9
BRD-K93754473-048-05-3
BSPBio_000252
BSPBio_001150
BSPBio_001982
C07108
C26H29NO
CCRIS 3275
CHEBI:41774
CHEMBL83
CID2733526
Citofen
Crisafeno
D08559
DB00675
Diemon
EINECS 234-118-0
Gen-Tamoxifen
Gen-tamoxifen
HMS1362J11
HMS1792J11
HMS1990J11
HMS2090N08
HSDB 6782
ICI 47699
ICI-46,474
ICI-47699
IDI1_000258
IDI1_002170
Istubol
Kessar
L024126
LS-393
Lopac0_001203
MLS001332535
MLS001332536
MolPort-003-850-384
 
NCGC00024928-01
NCGC00024928-03
NCGC00024928-04
NCGC00024928-05
NCGC00024928-07
NCGC00024928-08
NCGC00024928-09
NCGC00024928-12
NSC727681
Noltam
Nolvadex
Nolvadex-D
Nourytam
Novaldex
Novo-Tamoxifen
Oncomox
PMS-Tamoxifen
Pms-Tamoxifen
Prestwick2_000146
Prestwick3_000146
QTL1_000079
Retaxim
SMR000059172
ST50511785
Spectrum5_001417
Spectrum5_002043
T5648_SIGMA
TAMOXIFEN (TAMOXIFEN CITRATE (54965-24-1))
TRANS FORM OF TAMOXIFEN
Tamizam
Tamofen
Tamone
Tamoplex (TN)
Tamoxasta
Tamoxen
Tamoxifen
Tamoxifen (INN)
Tamoxifen (TN)
Tamoxifen (Z)
Tamoxifen Citrate
Tamoxifen [INN:BAN]
Tamoxifen and its salts
Tamoxifene
Tamoxifene [INN-French]
Tamoxifeno
Tamoxifeno [INN-Spanish]
Tamoxifenum
Tamoxifenum [INN-Latin]
Tamoxifène
Tocris-0999
Tomaxithen
Trans-Tamoxifen
UNII-094ZI81Y45
UPCMLD-DP027
Valodex
Zemide
cMAP_000044
nchembio.140-comp7
nchembio.76-comp1
nchembio732-comp3
tamoxifen
trans-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine
trans-Tamoxifen
47
CarboplatinapprovedPhase 2, Phase 1198041575-94-410339178, 498142, 38904
Synonyms:
(SP-4-2)-diammine[cyclobutane-1,1-dicarboxylato(2-)-kappa(2)O,O']platinum
/h1-3H2,(H,7,8)(H,9,10)
/q
1,1-Cyclobutanedicarboxylate diammine platinum (II)
1,1-Cyclobutanedicarboxylate diammine platinum(II)
2*-1
2*1H2
41575-94-4
70903-55-8
AC-1457
AC1L8I6U
Ambap41575-94-4
BSPBio_003145
C 2538
C2043
C2538_SIGMA
C6H10N2O4Pt
CBDCA
CCRIS 3404
CHEBI:31355
CHEMBL1351
CHEMBL288376
CID10339178
CID2567
CID38904
CID426756
CID498142
CID5352133
CID6398587
CID6603770
Carbopaltin
Carboplatin
Carboplatin (JAN/USP/INN)
Carboplatin (USAN)
Carboplatin [USAN:INN:BAN:JAN]
Carboplatine
Carboplatine [French]
Carboplatino
Carboplatino [Spanish]
Carboplatinum
Carboplatinum [Latin]
Cbdca
Cyclobutane-1,1-dicarboxylate
D01363
DB00958
Diammine(1,1-cyclobutanedicarboxylato)platinum (II)
Diammine(cyclobutane-1,1-dicarboxylato(2-)-O,O')platinum
Diammine-1,1-cyclobutane dicarboxylate platinum II
DivK1c_000892
EINECS 255-446-0
EU-0100230
Ercar
HMS1921J16
HMS2090M05
HMS2092B22
HMS502M14
HSDB 6957
I14-2390
IDI1_000892
IUPAC: Azane
InChI=1/C6H8O4.2H2N.Pt/c7-4(8)6(5(9)10)2-1-3-6
 
JM 8
JM-8
KBio1_000892
KBio2_002009
KBio2_004577
KBio2_007145
KBio3_002645
KBioGR_000713
KBioSS_002009
LS-117689
Lopac-C-2538
Lopac0_000230
MolPort-003-665-501
MolPort-003-845-609
NCGC00015223-01
NCGC00093695-01
NCGC00094961-01
NCGC00094961-02
NCGC00094961-03
NCGC00162099-01
NCGC00162099-02
NCGC00167800-01
NCGC00178242-01
NINDS_000892
NSC 201345
NSC 241240
NSC-241240
NSC201345
NSC241240
Paraplatin
Paraplatin (TN)
Paraplatin, Carboplatin
Paraplatin-AQ
Platinum(+2) Cation
Platinum(II), (1, 1-cyclobutanedicar
Platinum, diammine(1,1-cyclobutanedicarboxylato(2-)-O,O')-, (SP-4-2)
Platinum, {diammine[1,1-cyclobut
S1215_Selleck
SPBio_000716
SPECTRUM1502106
Spectrum2_000898
Spectrum3_001503
Spectrum4_000337
Spectrum5_001094
Spectrum_001529
UNII-BG3F62OND5
azanide
carboplatin
cis -Diammine[1,1-cyclobutane-dicarboxylato] platinum
cis-(1,1-Cyclobutanedicarboxylato)diammineplatinum(II)
cis-(1,1-Cyclobutanedicarboxylato)diammineplatinum(ii)
cis-Diamine(1,1-cyclobutanedicarboxylato)platinum(II)
cis-Diamine[1,1-cyclobutanedicarboxylato]platinum(II)
cis-Diammine(1,1-cyclobutanedicarboxylato) platinum
cis-Diammine(1,1-cyclobutanedicarboxylato)platinum
cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II)
cis-Diammine(cyclobutanedicarboxylato)platinum II
cyclobutane-1,1-dicarboxylic acid
diammine[cyclobutane-1,1-dicarboxylato(2-)-k2O1,O1]platinum
nchembio.573-comp10
nchembio773-comp2
nchembio873-comp3
platinum(2+)
48
Topotecanapproved, investigationalPhase 2339119413-54-6, 123948-87-860700
Synonyms:
(4S)-10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
(S)-10-((Dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione
(S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE
(S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]-quinoline-3,14(4H,12H)-dione
(S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
123948-87-8
9-Dimethylaminomethyl-10-hydroxycamptothecin
9-[(dimethylamino)Methyl]-10-hydroxy-(4S)-camptothecin
AC-11592
AC1L1TQZ
AC1Q6APZ
BSPBio_002348
C11158
C23H23N3O5
CCRIS 8163
CHEBI:107501
CHEBI:46035
CHEMBL84
CID60700
D08618
DB01030
HMS2090B20
HSCI1_000228
Hycamptamine
Hycamptin
Hycamtamine
Hycamtin
Hycamtin (TN)
LS-127395
 
MLS000759456
NCGC00178695-01
NCI60_004771
NCIStruc1_001659
NCIStruc2_001796
NChemBio.2007.10-comp24
NSC609699
SK&F-104864-A
SKF 104864
SKF-104864-A
SKF-S 104864
SMP2_000312
SMP2_000327
SMR000466344
TOPO
TOPOTECAN, HYCAMTIN
TPT
TTC
Topotecan (BAN)
Topotecan Hcl
Topotecan Hydrochloride
Topotecan Lactone
Topotecan Monohydrochloride, (S)-Isomer
Topotecan [INN:BAN]
Topotecan lactone
Topotecane
Topotecane [INN-French]
Topotecanum
Topotecanum [INN-Latin]
UNII-7M7YKX2N15
topotecan
49
CarmustineapprovedPhase 2, Phase 1212154-93-82578
Synonyms:
1,3-BIS(CHLOROETHYL)-1-NITROSOUREA
1,3-Bis(.beta.-chloroethyl)-1-nitrosourea
1,3-Bis(2-chloroethyl)-1-nitrosourea
1,3-Bis(2-chloroethyl)nitrosourea
1,3-Bis(beta-chloroethyl)-1-nitrosourea
154-93-8
AC-10563
AC1L1DZQ
AI3-52216
BCNU
BCNU [Chloroethyl nitrosoureas]
BRN 2049744
Becenum
Becenun
Bi CNU
BiCNU
BiCNU (TN)
Bicnu (tn)
Bio-0118
Bis(2-chloroethyl)1-nitrosourea
Bis(2-chloroethyl)nitrosourea
Bis(chloroethyl)nitrosourea
Bis-N,N'-(chloroethyl)nitrosourea
Bischlorethylnitrosourea
Bischlorethylnitrosurea
Bischloroethyl nitrosourea
Bischloroethyl nitrosourea [Chloroethyl nitrosoureas]
Bischloroethylnitrosourea
C 0400
C0400_SIGMA
C5H11Cl2N3O2
CCRIS 810
CHEBI:3423
CHEMBL513
CID2578
Carmubris
Carmustin
Carmustina
Carmustina [INN-Spanish]
Carmustine
Carmustine (USAN/INN)
Carmustine [USAN:INN:BAN]
Carmustinum
Carmustinum [INN-Latin]
D002330
D00254
DB00262
DTI 015
DivK1c_000835
EINECS 205-838-2
EU-0100188
 
FDA 0345
FIVB
FT-0083563
Gliadel
Gliadel Wafer
Gliadel, BCNU, NSC-409962, Becenun, Carmustine
HMS2092J22
HMS502J17
I14-11976
IDI1_000835
KBio1_000835
KBio2_000745
KBio2_003313
KBio2_005881
KBioGR_001296
KBioSS_000745
LS-890
Lopac-C-0400
Lopac0_000188
MLS001333962
MolPort-003-665-505
N,N'-BIS(2-CHLOROETHYL)-N-NITROSOUREA
N,N'-Bis(2-chloroethyl)-N-nitrosourea
NCGC00015204-01
NCGC00015204-02
NCGC00015204-06
NCGC00093665-01
NCGC00093665-02
NCGC00093665-03
NCGC00093665-04
NCI-C04773
NCI60_003931
NINDS_000835
NSC 409962
NSC-409962
NSC409962
Nitrumon
Prestwick_997
S1521_Selleck
SK 27702
SMR000058426
SRI 1720
STK624770
Spectrum4_000888
Spectrum5_000920
Spectrum_000265
UNII-U68WG3173Y
WLN: ONN2GVM2G
ZINC03830387
bis-chloroethylnitrosourea
carmustine
carmustine in ethanol
50
Gefitinibapproved, investigationalPhase 2351184475-35-2123631
Synonyms:
184475-35-2
4-(3'-Chloro-4'-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline
4-(3'-chloro-4'-Fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline
6-(3-morpholinopropoxy)-N-(3-chloro-4-fluorophenyl)-7-methoxyquinazolin-4-amine
AC-1556
AC1L3X0A
AKOS000280752
BCB03_000781
Bio-0046
C419708
CCRIS 9011
CHEBI:49668
CHEMBL939
CID123631
CU-00000000396-1
D01977
DB00317
DB07998
EC-000.2409
EN002708
FT-0081035
Gefitini
Gefitinib
Gefitinib (JAN/USAN/INN)
Gefitinib [USAN]
Gefitinib, Iressa, ZD1839
Gelfitinib
HMS2089B19
I01-1227
 
IRE
Iressa
Iressa (TN)
Iressa(TM)
Irressat
K00240
KBioSS_002241
Kinome_3321
Kinome_3322
LS-139916
MolPort-000-883-335
N-(3-Chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
N-(3-chloro-4-Fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamide
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine
NCGC00159455-02
NCGC00159455-03
NSC715055
S1025_Selleck
STK621310
UNII-S65743JHBS
ZD 1839
ZD-1839
ZD-1839, Iressa, Gefitinib
ZD1839
ZINC19632614
gefitinib
nchembio.117-comp18
nchembio866-comp14

Interventional clinical trials:

(show top 50)    (show all 68)
idNameStatusNCT IDPhase
1Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer PainCompletedNCT00538850Phase 3
2Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain TumorsCompletedNCT00369785Phase 3
3Observation or Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Low-Grade GliomaActive, not recruitingNCT00003375Phase 2, Phase 3
4Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for CancerTerminatedNCT01132547Phase 3
5Methylphenidate to Improve Quality of Life in Patients Undergoing Radiation Therapy for Brain TumorsTerminatedNCT00031798Phase 3
6Antineoplaston Therapy in Treating Patients With Low-Grade AstrocytomaUnknown statusNCT00003471Phase 2
7Temozolomide in Treating Patients With Low-Grade GliomaCompletedNCT00313729Phase 2
8Erlotinib and Temsirolimus in Treating Patients With Recurrent Malignant GliomaCompletedNCT00112736Phase 1, Phase 2
9Carmustine in Treating Adults With Recurrent Supratentorial Low-Grade GliomaCompletedNCT00003467Phase 2
10Gefitinib in Treating Patients With Recurrent or Progressive CNS TumorsCompletedNCT00025675Phase 2
11Temozolomide in Treating Patients With Progressive Low-Grade GliomaCompletedNCT00003466Phase 2
12Magnetic Resonance Imaging and Magnetic Resonance Spectroscopic Imaging in Evaluating Patients Who Are Undergoing Treatment for GliomasCompletedNCT00274755Phase 2
13Imatinib Mesylate in Treating Patients With GliomasCompletedNCT00039364Phase 2
14Temozolomide in Treating Patients With Recurrent Glioblastoma Multiforme or Other Malignant GliomaCompletedNCT00498927Phase 2
15Tamoxifen, Carboplatin, and Topotecan in Treating Patients With CNS Metastases or Recurrent Brain or Spinal Cord TumorsCompletedNCT00541138Phase 2
16Combination Chemotherapy and Tamoxifen in Treating Patients With Solid TumorsCompletedNCT00002608Phase 2
17Armodafinil in Treating Fatigue Caused By Radiation Therapy in Patients With Primary Brain TumorsCompletedNCT01032200Phase 2
18Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain CancersCompletedNCT00002752Phase 1, Phase 2
19Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain TumorsCompletedNCT00003461Phase 1, Phase 2
20Imatinib Mesylate in Treating Patients With Recurrent Malignant Glioma or MeningiomaCompletedNCT00010049Phase 1, Phase 2
21Phase II Studies Of Donepezil And Ginkgo Biloba In Irradiated Brain TumorCompletedNCT00070161Phase 2
22Antineoplaston Therapy in Treating Children With Brain TumorsCompletedNCT00003458Phase 2
23Antineoplaston Therapy in Treating Patients With Brain TumorsCompletedNCT00003457Phase 2
24Phase II Pegylated InterferonRecruitingNCT02343224Phase 2
25A Phase I Study of Mebendazole for the Treatment of Pediatric GliomasRecruitingNCT01837862Phase 1, Phase 2
26Photodynamic Therapy (PDT) For Recurrent High Grade GliomasRecruitingNCT01966809Phase 2
27Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal CancerRecruitingNCT00445965Phase 2
28Low-Dose or High-Dose Lenalidomide in Treating Younger Patients With Recurrent, Refractory, or Progressive Pilocytic Astrocytoma or Optic Pathway GliomaActive, not recruitingNCT01553149Phase 2
29Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade GliomaActive, not recruitingNCT01089101Phase 1, Phase 2
30Bevacizumab in Recurrent Grade II and III GliomaActive, not recruitingNCT01164189Phase 2
31Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed GlioblastomaActive, not recruitingNCT00553150Phase 1, Phase 2
32Crizotinib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell LymphomaActive, not recruitingNCT00939770Phase 1, Phase 2
33Functional Magnetic Resonance Imaging and 1H-Nuclear Magnetic Resonance Spectroscopic Imaging in Treating Patients With Newly Diagnosed Brain TumorsWithdrawnNCT00005083Phase 2
34Photodynamic Therapy With Porfimer Sodium in Treating Patients With Refractory Brain TumorsUnknown statusNCT00002647Phase 1
35RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant GliomaCompletedNCT01119599Phase 1
36Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney DysfunctionCompletedNCT00030498Phase 1
37Sodium Stibogluconate and IFNa-2b Followed By CDDP, VLB and DTIC Treating Pts.With Advanced Melanoma or Other CancersCompletedNCT00498979Phase 1
38Bortezomib and Temozolomide in Treating Patients With Brain Tumors or Other Solid Tumors That Have Not Responded to TreatmentCompletedNCT00544284Phase 1
39Erlotinib and Sirolimus in Treating Patients With Recurrent Malignant GliomaCompletedNCT00509431Phase 1
40MS-275 in Treating Patients With Advanced Solid Tumors or LymphomaCompletedNCT00020579Phase 1
41BCX-1777 in Treating Patients With Refractory CancerCompletedNCT00073944Phase 1
42Monoclonal Antibody Therapy in Treating Patients With Leptomeningeal CancerCompletedNCT00003022Phase 1
43Thalidomide and Docetaxel in Treating Patients With Advanced CancerCompletedNCT00049296Phase 1
44Carboxyamidotriazole and Paclitaxel in Treating Patients With Advanced Solid Tumors or Refractory LymphomasCompletedNCT00019019Phase 1
45Calcitriol Plus Carboplatin in Treating Patients With Advanced Solid TumorsCompletedNCT00008086Phase 1
46Yttrium Y 90 SMT 487 in Treating Patients With Refractory or Recurrent CancerCompletedNCT00006368Phase 1
47Radiolabeled Monoclonal Antibody Therapy After Radiation Therapy in Treating Patients With Primary Brain TumorsCompletedNCT00003484Phase 1
48Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or LymphomaCompletedNCT01273090Phase 1
49Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade GliomasRecruitingNCT02186509Phase 1
50Photodynamic Therapy (PDT) for Recurrent Pediatric Brain TumorsRecruitingNCT01682746Phase 1

Search NIH Clinical Center for Pilocytic Astrocytoma

Genetic Tests for Pilocytic Astrocytoma

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Genetic tests related to Pilocytic Astrocytoma:

id Genetic test Affiliating Genes
1 Pilocytic Astrocytoma27

Anatomical Context for Pilocytic Astrocytoma

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MalaCards organs/tissues related to Pilocytic Astrocytoma:

36
Brain, Spinal cord, Cerebellum, Liver, Bone, Pineal, Kidney

FMA organs/tissues related to Pilocytic Astrocytoma:

17
The brain

Publications for Pilocytic Astrocytoma

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Articles related to Pilocytic Astrocytoma:

(show top 50)    (show all 384)
idTitleAuthorsYear
1
Longitudinal mutational analysis of a cerebellar pilocytic astrocytoma recurring as a ganglioglioma. (27718322)
2017
2
Coexistent dysembryoplastic neuroepithelial tumour and pilocytic astrocytoma. (27695565)
2016
3
Whole Chromosome 7 Gain Predicts Higher Risk of Recurrence in Pediatric Pilocytic Astrocytomas Independently From KIAA1549-BRAF Fusion Status. (26945035)
2016
4
A rare case of infantile cerebellar pilocytic astrocytoma and thrombocytopenia presenting with intratumoral hemorrhage. (27857799)
2016
5
Low rates of recurrence and slow progression of pediatric pilocytic astrocytoma after gross-total resection: justification for reducing surveillance imaging. (26722760)
2016
6
Retraction: Screening genes crucial for pediatric pilocytic astrocytoma using weighted gene coexpression network analysis combined with methylation data analysis. (26685762)
2016
7
TP53 codon 72 polymorphism may predict early tumour progression in paediatric pilocytic astrocytoma. (27374106)
2016
8
Tanycytic ependymoma vs pilocytic astrocytoma? Pitfalls in diagnosis. (27773093)
2016
9
Primary Orbital Cystic Pilocytic Astrocytoma. (27843910)
2016
10
Pilocytic astrocytoma and glioneuronal tumor with histone H3 K27M mutation. (27519587)
2016
11
Spontaneous complete regression of hypothalamic pilocytic astrocytoma after partial resection in a child, complicated with Stevens-Johnson syndrome: a case report and literature review. (26662551)
2016
12
Malignant progression of a histone H3.3 K27M-mutated spinal pilocytic astrocytoma in an adult. (27900936)
2016
13
Leptomeningeal dissemination and vertebral bone involvement in a child with pilocytic astrocytoma. (27859985)
2016
14
Genetic alterations related to BRAF-FGFR genes and dysregulated MAPK/ERK/mTOR signaling in adult pilocytic astrocytoma. (27608415)
2016
15
Report of effective trametinib therapy in 2 children with progressive hypothalamic optic pathway pilocytic astrocytoma: documentation of volumetric response. (28009226)
2016
16
Hypothalamic-Optochiasmatic Pilocytic Astrocytoma Associated with Occipital and Sacral Spinal Cavernomas: A Mere Coincidence or a True Association? (27004758)
2016
17
MRS of pilocytic astrocytoma: The peak at 2a88ppm may not be NAA. (27529659)
2016
18
Massive Calcified Cerebellar Pilocytic Astrocytoma with Rapid Recurrence : A Rare Case. (27651876)
2016
19
Pilocytic Astrocytoma of fornix mimicking a colloid cyst: report of two cases and review of the literature. (28024978)
2016
20
Suprasellar pilocytic astrocytoma in an adult with hemorrhage and leptomeningeal dissemination: case report and review of literature. (27920871)
2016
21
Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing. (28002790)
2016
22
Postoperative surveillance of pediatric cerebellar pilocytic astrocytoma. (27502785)
2016
23
A new NFIA:RAF1 fusion activating the MAPK pathway in pilocytic astrocytoma. (27810072)
2016
24
A case of pilocytic astrocytoma requiring tumor resection during pregnancy. (27073664)
2016
25
Using urinary bFGF and TIMP3 levels to predict the presence of juvenile pilocytic astrocytoma and establish a distinct biomarker signature. (27314542)
2016
26
Cranial pilocytic astrocytoma with spinal drop metastasis in an adult: case report and literature review. (27535634)
2016
27
Spontaneous aneurysmal subarachnoid haemorrhage in a child with multiply recurrent posterior fossa juvenile pilocytic astrocytoma. (27927709)
2016
28
Diffuse Spinal Leptomeningeal Spread of a Pilocytic Astrocytoma in a 3-year-old Child. (27162602)
2016
29
Heterogeneity of histopathological presentation of pilocytic astrocytoma - diagnostic pitfalls. A review. (27764513)
2016
30
Pineal region pilocytic astrocytoma; an unusual site with variable radiological, clinical, and histological features: A report of two cases. (27365971)
2016
31
MR imaging of brain pilocytic astrocytoma: beyond the stereotype of benign astrocytoma. (27757570)
2016
32
Adult anaplastic pilocytic astrocytoma - a diagnostic challenge? A case series and literature review. (27341279)
2016
33
Infratentorial ganglioglioma mimicking pilocytic astrocytoma. (27936528)
2016
34
Cervical spinal pilocytic astrocytoma. (26916806)
2016
35
Pilocytic astrocytoma. (27033282)
2016
36
Long survival in a child with a mutated K27M-H3.3 pilocytic astrocytoma. (25909089)
2015
37
Transcriptional profiles of pilocytic astrocytoma are related to their three different locations, but not to radiological tumor features. (26497896)
2015
38
Spinal hemangioblastoma combined with pilocytic astrocytoma. (26166599)
2015
39
Non-random aneuploidy specifies subgroups of pilocytic astrocytoma and correlates with older age. (26378811)
2015
40
Hodgkin's lymphoma in an adolescent previously treated with surgical resection of third ventricular juvenile pilocytic astrocytoma. (26113587)
2015
41
Grade II pilocytic astrocytoma in a 3-month-old patient with encephalocraniocutaneous lipomatosis (ECCL): Case report and literature review of low grade gliomas in ECCL. (25705862)
2015
42
Nocardia farcinica Meningitis Masquerading as Central Nervous System Metastasis in a Child With Cerebellar Pilocytic Astrocytoma. (26181420)
2015
43
Adult recurrent pilocytic astrocytoma: Clinical, histopathological and molecular study. (26597605)
2015
44
Expression of Methylthioadenosine Phosphorylase (MTAP) in Pilocytic Astrocytomas. (26088413)
2015
45
Unusual presentation of unilateral intra-orbital optic nerve pilocytic astrocytoma of the juvenile type in a geriatric patient. (26549677)
2015
46
Nasal heterotopia versus pilocytic astrocytoma: A narrow border. (26072230)
2015
47
Pilocytic astrocytoma: pathology, molecular mechanisms and markers. (25792358)
2015
48
High accuracy of arterial spin labeling perfusion imaging in differentiation of pilomyxoid from pilocytic astrocytoma. (25666232)
2015
49
Biphasic response of a tecto-mesencephalic pilocytic astrocytoma after Gamma Knife surgery--A case report. (26072229)
2015
50
Adult cervicomedullary pilocytic astrocytoma: A case report. (26668620)
2015

Variations for Pilocytic Astrocytoma

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Copy number variations for Pilocytic Astrocytoma from CNVD:

6 (show all 22)
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1381611013000000GainDIP2CPilocytic astrocytoma
24059910130600000135534747LossDRD1IPPilocytic astrocytoma
36453712129300000133851895LossBCL7APilocytic astrocytoma
484233142460000033300000LossFOXG1BPilocytic astrocytoma
5970791598500000102531392LossLASS3Pilocytic astrocytoma
6112680174081126540819024LossTUBG2Pilocytic astrocytoma
7112684174083463140852011LossCNTNAP1Pilocytic astrocytoma
82203997138200000143100000AmplificationPilocytic astrocytoma
922790177220000077500000LossBCL7BPilocytic astrocytoma
10230764812200000LossPilocytic astrocytoma
112345638136400000146364022GainCOL22A1Pilocytic astrocytoma
122348738139900000146364022GainCYHR1Pilocytic astrocytoma
132348788139900000146364022GainFOXH1Pilocytic astrocytoma
142348818139900000146364022GainGPTPilocytic astrocytoma
152348848139900000146364022GainKIFC2Pilocytic astrocytoma
162348868139900000146364022GainLRRC14Pilocytic astrocytoma
172348888139900000146364022GainLRRC24Pilocytic astrocytoma
182348908139900000146364022GainMFSD3Pilocytic astrocytoma
192348938139900000146364022GainPPP1R16APilocytic astrocytoma
202348978139900000146364022GainRECQL4Pilocytic astrocytoma
21244900912200000LossANKRD15Pilocytic astrocytoma
222561919900000028000000LossSH3GL2Pilocytic astrocytoma

Expression for genes affiliated with Pilocytic Astrocytoma

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Search GEO for disease gene expression data for Pilocytic Astrocytoma.

Pathways for genes affiliated with Pilocytic Astrocytoma

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Pathways related to Pilocytic Astrocytoma according to GeneCards Suite gene sharing:

(show top 50)    (show all 67)
idSuper pathwaysScoreTop Affiliating Genes
110.2NF1, PTPN11
210.2HRAS, KRAS
310.1BRAF, KRAS, RAF1
410.1BRAF, KRAS, RAF1
5
Show member pathways
10.1BRAF, NF1, RAF1
610.1BRAF, NF1, RAF1
710.0BRAF, HRAS, KRAS
810.0BRAF, HRAS, RAF1
910.0HRAS, KRAS, RAF1
10
Show member pathways
10.0FGFR1, HRAS, KRAS
1110.0ERBB3, FGFR1, NTRK2
1210.0HRAS, PTPN11, RAF1
1310.0HRAS, PTPN11, RAF1
14
Show member pathways
10.0HRAS, PTPN11, RAF1
1510.0HRAS, PTPN11, RAF1
1610.0HRAS, PTPN11, RAF1
1710.0ERBB3, HRAS, KRAS
18
Show member pathways
9.9BRAF, HRAS, KRAS, RAF1
199.9BRAF, HRAS, KRAS, RAF1
20
Show member pathways
9.9BRAF, HRAS, KRAS, RAF1
21
Show member pathways
9.9BRAF, HRAS, KRAS, RAF1
22
Show member pathways
9.9BRAF, HRAS, KRAS, RAF1
239.9BRAF, HRAS, KRAS, RAF1
24
Show member pathways
9.9BRAF, HRAS, KRAS, RAF1
25
Show member pathways
9.9BRAF, HRAS, KRAS, RAF1
269.9BRAF, HRAS, KRAS, RAF1
27
Show member pathways
9.9BRAF, HRAS, KRAS, RAF1
289.9FGFR1, HRAS, KRAS, RAF1
29
Show member pathways
9.9HRAS, KRAS, NTRK2, RAF1
30
Show member pathways
9.9HRAS, KRAS, PTPN11, RAF1
319.9HRAS, KRAS, PTPN11, RAF1
329.9BRAF, CDKN2A, HRAS, RAF1
339.9HRAS, NTRK2, PTPN11, RAF1
349.9FGFR1, GFAP, OLIG2, SOX10
35
Show member pathways
9.8ERBB3, HRAS, KRAS, NF1
36
Show member pathways
9.8BRAF, FGFR1, HRAS, KRAS, RAF1
37
Show member pathways
9.8BRAF, FGFR1, HRAS, KRAS, RAF1
389.8BRAF, FGFR1, HRAS, KRAS, RAF1
39
Show member pathways
9.8BRAF, HRAS, KRAS, NTRK2, RAF1
409.8BRAF, HRAS, KRAS, PTPN11, RAF1
41
Show member pathways
9.8BRAF, HRAS, KRAS, PTPN11, RAF1
42
Show member pathways
9.8BRAF, HRAS, KRAS, PTPN11, RAF1
439.8FGFR1, HRAS, IDH1, KRAS, RAF1
44
Show member pathways
9.8FGFR1, HRAS, KRAS, PTPN11, RAF1
459.7HRAS, KRAS, PTPN11, RAF1, SRGAP3
469.7BRAF, CDKN2A, HRAS, KRAS, RAF1
47
Show member pathways
9.7BRAF, ERBB3, HRAS, KRAS, RAF1
48
Show member pathways
9.7ERBB3, FGFR1, HRAS, KRAS, NTRK2
499.7CDKN2A, ERBB3, HRAS, KRAS, RAF1
50
Show member pathways
9.7BRAF, ERBB3, FGFR1, KRAS, NTRK2, RAF1

GO Terms for genes affiliated with Pilocytic Astrocytoma

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Cellular components related to Pilocytic Astrocytoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytosolGO:00058298.8BRAF, CDKN2A, FGFR1, GFAP, HRAS, IDH1

Biological processes related to Pilocytic Astrocytoma according to GeneCards Suite gene sharing:

(show all 26)
idNameGO IDScoreTop Affiliating Genes
1forebrain astrocyte developmentGO:002189711.0KRAS, NF1
2Bergmann glial cell differentiationGO:006002010.9GFAP, PTPN11
3positive regulation of cellular senescenceGO:200077410.9CDKN2A, KRAS
4long-term synaptic potentiationGO:006029110.8BRAF, GFAP, NTRK2
5positive regulation of peptidyl-serine phosphorylationGO:003313810.8BRAF, NTRK2, RAF1
6epidermal growth factor receptor signaling pathwayGO:000717310.8HRAS, KRAS, PTPN11
7oligodendrocyte differentiationGO:004870910.7NTRK2, OLIG2, SOX10
8ERBB2 signaling pathwayGO:003812810.7ERBB3, HRAS, KRAS
9positive regulation of MAP kinase activityGO:004340610.7FGFR1, HRAS, KRAS
10peripheral nervous system developmentGO:000742210.7ERBB3, NF1, SOX10
11positive regulation of phosphatidylinositol 3-kinase signalingGO:001406810.7ERBB3, FGFR1, NTRK2
12positive regulation of MAPK cascadeGO:004341010.7FGFR1, HRAS, NTRK2
13regulation of synaptic transmission, GABAergicGO:003222810.7KRAS, NF1
14regulation of protein complex assemblyGO:004325410.6GFAP, PTPN11
15heart developmentGO:000750710.6ERBB3, NF1, PTPN11, RAF1
16brain developmentGO:000742010.6APOD, FGFR1, NF1, PTPN11
17positive regulation of protein phosphorylationGO:000193410.5HRAS, KRAS, NTRK2, RAF1
18regulation of phosphatidylinositol 3-kinase signalingGO:001406610.5ERBB3, FGFR1, PTPN11
19Ras protein signal transductionGO:000726510.5CDKN2A, HRAS, KRAS, NF1
20regulation of cell proliferationGO:004212710.5BRAF, ERBB3, FGFR1, NF1
21negative regulation of neuron apoptotic processGO:004352410.4BRAF, ERBB3, HRAS, KRAS, NTRK2
22positive regulation of gene expressionGO:001062810.4BRAF, ERBB3, HRAS, KRAS, NTRK2
23regulation of long-term neuronal synaptic plasticityGO:004816910.4HRAS, KRAS, NF1, SYP
24negative regulation of cell proliferationGO:000828510.4CDKN2A, HRAS, NF1, NFIB, RAF1
25MAPK cascadeGO:000016510.2BRAF, ERBB3, FGFR1, HRAS, KRAS, NF1
26visual learningGO:000854210.1BRAF, KRAS, NF1

Molecular functions related to Pilocytic Astrocytoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1identical protein bindingGO:004280210.0BRAF, ERBB3, FGFR1, RAF1, SOX10, SYP
2phosphatidylinositol-4,5-bisphosphate 3-kinase activityGO:004693410.0ERBB3, FGFR1, PTPN11

Sources for Pilocytic Astrocytoma

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet