MCID: PLM021
MIFTS: 34

Pilomyxoid Astrocytoma malady

Neuronal diseases, Cancer diseases, Rare diseases categories

Summaries for Pilomyxoid Astrocytoma

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34MalaCards
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MalaCards: Pilomyxoid Astrocytoma is related to astrocytoma and pilocytic astrocytoma. An important gene associated with Pilomyxoid Astrocytoma is SYP (synaptophysin), and among its related pathways are Neuroscience and Regulation of RAC1 activity. The compounds n-acetylaspartate and s 100 have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, cerebellum and hypothalamus.

Aliases & Classifications for Pilomyxoid Astrocytoma

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Sources:
9Disease Ontology, 11DISEASES, 50Orphanet, 63UMLS, 41NCIt, 59SNOMED-CT, 60SNOMED-CT via Orphanet, 64UMLS via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases
Anatomical: Neuronal diseases


Characteristics (Orphanet epidemiological data):

50
pilomyxoid astrocytoma:
Inheritance: Sporadic; Age of onset: Variable


Aliases & Descriptions:

pilomyxoid astrocytoma 9 11 50 63


External Ids:

Disease Ontology9 DOID:4845
NCIt41 C40315
SNOMED-CT59 388600004
SNOMED-CT via Orphanet60 388600004
UMLS via Orphanet64 C1519086

Related Diseases for Pilomyxoid Astrocytoma

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Sources:
18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Pilomyxoid Astrocytoma:



Diseases related to pilomyxoid astrocytoma

Symptoms for Pilomyxoid Astrocytoma

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Drugs & Therapeutics for Pilomyxoid Astrocytoma

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Pilomyxoid Astrocytoma

Search CenterWatch for Pilomyxoid Astrocytoma

Genetic Tests for Pilomyxoid Astrocytoma

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Anatomical Context for Pilomyxoid Astrocytoma

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34MalaCards
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MalaCards organs/tissues related to Pilomyxoid Astrocytoma:

34
Spinal cord, Cerebellum, Hypothalamus

Animal Models for Pilomyxoid Astrocytoma or affiliated genes

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Publications for Pilomyxoid Astrocytoma

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53PubMed
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Articles related to Pilomyxoid Astrocytoma:

(show all 47)
idTitleAuthorsYear
1
Insulin-like growth factor 2 mRNA binding protein 3 expression is an independent prognostic factor in pediatric pilocytic and pilomyxoid astrocytoma. (23584203)
2013
2
Significance of radical resection for pilomyxoid astrocytoma of the cerebellum: a case report and review of the literature. (23503634)
2013
3
Pediatric spinal pilomyxoid astrocytoma. (24053650)
2013
4
Pilomyxoid astrocytoma of the cerebellum with Williams syndrome: a case report. (23604363)
2013
5
Sustained response to weekly vinblastine in 2 children with pilomyxoid astrocytoma associated with diencephalic syndrome. (23042016)
2013
6
Response. Pilomyxoid astrocytoma. (23767070)
2013
7
Pilomyxoid astrocytoma of the brainstem. (23888217)
2013
8
Response. Pilomyxoid astrocytoma. (23767069)
2013
9
Pilomyxoid astrocytoma. (23495811)
2013
10
Occurrence and distribution of pilomyxoid astrocytoma. (23281683)
2013
11
Successful treatment of leptomeningeal gliomatosis of pilomyxoid astrocytoma after failed frontline chemotherapy. (22217612)
2012
12
Temporal and optic pathway pilomyxoid astrocytoma mimicking dural-based lesion: case report and review of the literature. (23548417)
2012
13
Intramedullary pilomyxoid astrocytoma with intracerebral metastasis exhibiting oligoden-droglioma-like features. (22826787)
2012
14
T2 and DWI in pilocytic and pilomyxoid astrocytoma with pathologic correlation. (22728857)
2012
15
Intermediate pilomyxoid astrocytoma and diencephalic syndrome: imaging findings. (23052462)
2012
16
Pilomyxoid astrocytoma of the cerebellum. (21529196)
2011
17
Pilomyxoid astrocytoma in cerebellum. (23467810)
2011
18
Diencephalic juvenile pilomyxoid astrocytoma with leptomeningeal dissemination. (21534206)
2011
19
Pilomyxoid astrocytoma of the cervical spinal cord in a child with rapid progression into glioblastoma: case report and literature review. (20461521)
2011
20
Pilomyxoid astrocytoma. (20551536)
2010
21
Pilomyxoid astrocytoma in unusual location in a child with neurofibromatosis type 1: case report and review of the literature. (20496528)
2010
22
Pilomyxoid astrocytoma of the cervical spinal cord successfully treated with chemotherapy: case report. (21030812)
2010
23
Juvenile pilomyxoid astrocytoma in the opticohypothalamus. (21286484)
2010
24
A case of pilomyxoid astrocytoma presenting with CSF rhinorrhoea in a 15-year-old. (19718549)
2009
25
Pilomyxoid astrocytoma with involvement of the sella turcica in an adolescent. (19766001)
2009
26
Hemorrhagic onset of pilocytic astrocytoma and pilomyxoid astrocytoma. (19408090)
2009
27
Pilomyxoid astrocytoma of the spinal cord with cerebrospinal fluid and peritoneal metastasis. (19165714)
2008
28
Magnetic resonance imaging characteristics of pilomyxoid astrocytoma. (18662499)
2008
29
Pilomyxoid astrocytoma of the fourth ventricle in an adult. (18958385)
2008
30
Pilomyxoid astrocytoma of the spinal cord in an adult. (18536992)
2008
31
Pilomyxoid astrocytoma: expanding the imaging spectrum. (18701580)
2008
32
Clinicopathological features and global genomic copy number alterations of pilomyxoid astrocytoma in the hypothalamus/optic pathway: comparative analysis with pilocytic astrocytoma using array-based comparative genomic hybridization. (18622384)
2008
33
Pilomyxoid astrocytoma in a patient presenting with fatal hemorrhage. Case report. (18352771)
2008
34
Occipital pilomyxoid astrocytoma in a 14-year-old girl--case report. (19130733)
2008
35
Pilomyxoid astrocytoma: neuroimaging with clinicopathologic correlates in 4 cases followed over time. (17609624)
2007
36
The pilomyxoid astrocytoma and its relationship to pilocytic astrocytoma: report of a case and a critical review of the entity. (16850101)
2007
37
Spinal cord pilomyxoid astrocytoma: an unusual tumor. (17894633)
2007
38
Newly codified glial neoplasms of the 2007 WHO Classification of Tumours of the Central Nervous System: angiocentric glioma, pilomyxoid astrocytoma and pituicytoma. (17598825)
2007
39
BCR gene disruption in a pilomyxoid astrocytoma. (17080723)
2006
40
Pilomyxoid astrocytoma in a patient with neurofibromatosis. (15800886)
2006
41
Glioneuronal phenotype in a diencephalic pilomyxoid astrocytoma. (17163791)
2006
42
Radiotherapy plus concomitant and adjuvant temozolomide for leptomeningeal pilomyxoid astrocytoma: a case study. (16645715)
2006
43
Pilomyxoid astrocytoma: diagnosis, prognosis, and management. (16048293)
2005
44
Pilomyxoid astrocytoma of the spinal cord: report of three cases. (15617606)
2005
45
Clinico-pathological features of pilomyxoid astrocytoma of the optic pathway. (15168135)
2004
46
Pilomyxoid astrocytoma: a review. (15775869)
2004
47
Spontaneous hemorrhage associated with a pilomyxoid astrocytoma. Case report. (12924720)
2003

Variations for Pilomyxoid Astrocytoma

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Expression for genes affiliated with Pilomyxoid Astrocytoma

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Pilomyxoid Astrocytoma

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Pathways for genes affiliated with Pilomyxoid Astrocytoma

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51PathCards, 5Cell Signaling Technology, 39NCBI BioSystems Database, 61Thomson Reuters
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Pathways related to Pilomyxoid Astrocytoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4SYP, GFAP
29.1BCR, DOCK6
39.1BCR, DOCK6

Compounds for genes affiliated with Pilomyxoid Astrocytoma

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Sources:
46Novoseek, 30IUPHAR, 25HMDB, 12DrugBank, 52PharmGKB, 62Tocris Bioscience, 3BitterDB
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Compounds related to Pilomyxoid Astrocytoma according to GeneCards/GeneDecks:

(show all 23)
idCompoundScoreTop Affiliating Genes
1n-acetylaspartate469.7SYP, GFAP
2s 100469.7GFAP, SYP
3reticulin469.7SYP, GFAP
4dutp469.7GFAP, SYP
5streptozotocin469.7SYP, GFAP
6hematoxylin469.7SYP, GFAP
7dbc-amp469.7SYP, GFAP
8silver469.6SYP, GFAP
9kainate46 3010.6SYP, GFAP
105-hydroxytryptamine469.6SYP, GFAP
11choline46 25 1211.5SYP, GFAP
12formaldehyde46 2510.4SYP, GFAP
13gaba469.4SYP, GFAP
14acth469.3GFAP, SYP
15cytarabine46 52 1211.2GFAP, BCR
16inositol469.2BCR, GFAP
17ganglioside468.9BCR, SYP, GFAP
18genistein46 30 62 3 25 1213.9BCR, SYP, GFAP
19leucine468.9GFAP, SYP, BCR
20cholesterol46 30 25 1211.8GFAP, SYP, BCR
21cysteine468.7GFAP, SYP, BCR
22tyrosine468.4BCR, SYP, GFAP, IGF2BP3
23lipid468.3BCR, SYP, GFAP

GO Terms for genes affiliated with Pilomyxoid Astrocytoma

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17Gene Ontology
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Cellular components related to Pilomyxoid Astrocytoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein complexGO:0432349.2BCR, SYP
2cytosolGO:0058297.7BCR, DOCK6, GFAP, IGF2BP3

Products for genes affiliated with Pilomyxoid Astrocytoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Pilomyxoid Astrocytoma

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet