MCID: PTT004
MIFTS: 38

Pituitary Apoplexy malady

Categories: Endocrine diseases, Rare diseases

Aliases & Classifications for Pituitary Apoplexy

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Sources:
11Disease Ontology, 13DISEASES, 52Orphanet, 48Novoseek, 37MeSH, 66UMLS, 43NCIt, 67UMLS via Orphanet, 29ICD10 via Orphanet, 38MESH via Orphanet, 60SNOMED-CT
See all MalaCards sources

Aliases & Descriptions for Pituitary Apoplexy:

Name: Pituitary Apoplexy 11 13 52 48 37 66

Characteristics:

Orphanet epidemiological data:

52
pituitary apoplexy:
Inheritance: Not applicable; Age of onset: All ages

Classifications:



External Ids:

Disease Ontology11 DOID:1129
MeSH37 D010899
NCIt43 C26853
Orphanet52 ORPHA95613
SNOMED-CT60 237701005
UMLS via Orphanet67 C0032001
ICD10 via Orphanet29 E23.6
MESH via Orphanet38 D010899

Summaries for Pituitary Apoplexy

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Wikipedia:69 Pituitary apoplexy or pituitary tumor apoplexy is bleeding into or impaired blood supply of the... more...

MalaCards based summary: Pituitary Apoplexy is related to diabetes insipidus and acromegaly. An important gene associated with Pituitary Apoplexy is POMC (Proopiomelanocortin), and among its related pathways are Glucocorticoid receptor regulatory network and Signaling events mediated by PTP1B. Affiliated tissues include pituitary, brain and testes, and related mouse phenotypes are neoplasm and liver/biliary system.

Related Diseases for Pituitary Apoplexy

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Diseases related to Pituitary Apoplexy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 162)
idRelated DiseaseScoreTop Affiliating Genes
1diabetes insipidus28.8GNRH1, INS, POMC, PRL
2acromegaly10.5
3adenoma10.5
4pituitary adenoma10.4
5cerebritis10.4
6meningitis10.3
7aneurysm10.3
8hemiplegia alterans10.3INS, PRL
9ehlers-danlos syndrome, type viii10.3AIP, PRL
10paranasal sinus cancer, adult10.3INS, PRL
11prostatitis10.3
12hypopituitarism10.3
13scleredema adultorum10.2INS, PRL
14pituitary adenoma, prolactin-secreting10.2AIP, PRL
15cranial nerve palsy10.2
16prolactinoma10.2
17headache10.2
18benign prostate phyllodes tumor10.2GNRH1, PRL
19dysthymic disorder10.2INS, PRL
20prostate cancer10.2
21lymphoma10.1
22aromatase excess syndrome10.1GNRH1, INS
23gender identity disorder10.1GNRH1, PRL
24thrombocytopenia10.1
25ptosis10.1
26dengue hemorrhagic fever10.0
27adenocarcinoma10.0
28empty sella syndrome10.0
29functioning pituitary adenoma10.0
30thyroiditis10.0
31carotid artery occlusion10.0
32bacterial meningitis10.0
33lymphocytic hypophysitis10.0
34hemorrhagic fever10.0
35non-functioning pituitary adenoma10.0
36aneurysm or dilatation of ascending aorta10.0POMC, PRL
37lactic acidosis10.0POMC, PRL
38colloid carcinoma of the pancreas10.0POMC, PRL
39acute myeloid leukemia, kit-related10.0POMC, PRL
40hypothryoidism, congenital, nongoitrous 410.0POMC, PRL
41immune system organ benign neoplasm10.0POMC, PRL
42congenital epulis10.0POMC, PRL
43diencephalic neoplasm10.0GNRH1, INS
44acute myocarditis10.0POMC, PRL
45loeffler endocarditis9.9POMC, PRL
46nasopharyngeal disease9.9POMC, PRL
47benign eccrine breast spiradenoma9.9INS, POMC
48leukemia9.9
49meningoencephalitis9.9
50optic neuritis9.9

Graphical network of the top 20 diseases related to Pituitary Apoplexy:



Diseases related to pituitary apoplexy

Symptoms for Pituitary Apoplexy

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Drugs & Therapeutics for Pituitary Apoplexy

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Drugs for Pituitary Apoplexy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
OxytocinPhase 239050-56-6439302, 53477758
Synonyms:
(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
(Arg8)-Vasopressin
(Arg8)-Vasotocin
1-({(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-(4-hydroxybenzyl)-13-[(1S)-1-methylpropyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}carbonyl)-L-prolyl-L-leucylglycinamide
50-56-6
AC1L9735
Argipressin
Argpressin Acetate
BCBcMAP01_000094
Biotinyl-(Arg8)-Vasopressin
C00746
CHEBI:492195
CHEBI:7872
CHEMBL395429
CID439302
Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-NH2
Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2
Cys-Tyr-Ile-Thr-Asn-Cys-Gly-Leu-Gly-NH2
Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2
Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2
D00089
Disulfide bridge Cys1-Cys6
Gly-Leu-Pro-c
HS-2021
 
L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic(1-6)-disulfide
MolPort-003-938-941
NCGC00167132-01
O3251_SIGMA
O4375_SIGMA
OXT
OXYTOCIN
Ocytocin
Oxitocina
Oxytocic hormone
Oxytocin (JP15/USP/INN)
Oxytocin (TN)
Oxytocin 10 Usp Units In Dextrose 5%
Oxytocin 20 Usp Units In Dextrose 5%
Oxytocin 5 Usp Units In Dextrose 5%
Oxytocin Acetate
Oxytocin injection
Oxytocine
Oxytocinum
Pitocin
Pitocin (TN)
Syntocinon
Syntocinon (TN)
TI-001
alpha-Hypophamine
nchembio.184-comp2
2insulin4401
3
Zinc21547440-66-632051, 23994
Synonyms:
30Zn
Cinc
Zinc
Zinc ion
 
Zincum
Zink
Zn
Zn(ii)
Zn2+
4glucagon441
5
butyric acid350107-92-6264
Synonyms:
1-Butanoate
1-Butanoic acid
1-Butyrate
1-Butyric acid
1-Propanecarboxylate
1-Propanecarboxylic acid
Butanate
Butanic acid
Butanoate
Butanoic acid
Buttersaeure
Butyrate
 
Butyric acid
Ethylacetate
Ethylacetic acid
Honey robber
Kyselina maselna
N-Butanoate
N-Butanoic acid
N-Butyrate
N-Butyric acid
Propanecarboxylate
Propanecarboxylic acid
Propylformate
Propylformic acid
6
Hydrocortisone60250-23-75754, 657311
Synonyms:
(11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione
(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione
11-Hydrocortisone
11-beta-Hydrocortisone
11-beta-Hydroxycortisone
11a-Hydroxycorticosterone
11alpha-Hydroxycorticosterone
11b,17,21-Trihydroxyprogesterone
11b-Hydrocortisone
11b-Hydroxycortisone
11beta,17,21-Trihydroxyprogesterone
11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione
11beta-Hydrocortisone
11beta-Hydroxycortisone
11beta-hydrocortisone
11β-hydrocortisone
17-Hydroxycorticosterone
17a-Hydroxycorticosterone
17alpha-Hydroxycorticosterone
2v95
4-Pregnen-11beta,17alpha,21-triol-3,20-dione
4-Pregnene-11alpha,21-triol 3,20-dione
4-Pregnene-11b,17a,21-triol-3,20-dione
50-23-7
8056-08-4
80562-38-5
8063-42-1
AC-12902
AC1L1L2B
ACETASOL HC
ACETIC ACID W/ HYDROCORTISONE
AI3-25006
AKOS001582651
Acticort
Acticort (TN)
Aeroseb HC
Aeroseb-HC
Ala-Cort
Ala-Scalp
Alacort
Algicirtis
Alphaderm
Amberin
Anflam
Anti-inflammatory hormone
Anucort
Anucort-HC
Anusol HC
Anusol HC (TN)
Aquacort
Aquanil HC
B48448A1-24BA-47CA-8D9E-43E5BC949386
BPBio1_000544
BRD-K93568044-001-03-1
BSPBio_000494
Balneol-hc
Barseb HC
Basan-Corti
Beta-hc
Bio-0648
C00735
C21H30O5
CCRIS 5854
CHEBI:17650
CHEMBL389621
CID5754
COR-OTICIN
CPD000653523
CaldeCORT Spray
Cetacort
Chronocort
Clear aid
Cleiton
Cobadex
Colocort
Colocort (TN)
Compound F
Compound F (kendall)
Cor-Tar-Quin
Corhydron
Cort-Dome
Cort-Quin
Cortanal
Cortef
Cortef (TN)
Cortenema
Cortesal
Corticreme
Cortifair
Cortifan
Cortifoam
Cortiment
Cortisol
Cortisol alcohol
Cortisol, Hydrocortisone
Cortisolonum
Cortisporin
Cortisporin Otico
Cortispray
Cortizol
Cortolotion
Cortonema
Cortoxide
Cortril
Cremesone
Cremicort-H
Cutisol
Cyclodextrin-encapsulated hydrocortisone
D00088
DB00741
DB07886
Delacort
Derm-Aid
Dermacort
Dermaspray
Dermil
Dermocortal
Dermolate
Dihydrocostisone
Dioderm
Dome-cort
Domolene-HC
Drotic
DuoCort
EINECS 200-020-1
EU-0100594
Ef corlin
Efcorbin
Efcortelan
Efcortelin
Eldecort
Eldercort
Epicort
Epicortisol
Epiderm H
Esiderm H
Evacort
Ficortril
Fiocortril
Flexicort
Foille Insetti
Genacort
Genacort (lotion)
Glycort
Gyno-Cortisone
H 4001
H-Cort
H0135_SIGMA
H0396_SIGMA
H0888_SIGMA
H3160_SIGMA
H4001_SIGMA
H6909_SIGMA
HC
HC #1
 
HC #4
HC (HYDROCORTISONE)
HMS1569I16
HMS2090M04
HSDB 3339
HYDROCORTISONE AND ACETIC ACID
HYDROCORTISONE IN ABSORBASE
Heb Cort
Heb-Cort
Hi-cor
Hidalone
Hidro-Colisona
Hidrocortisona
Hidrocortisona [INN-Spanish]
Hycort
Hycortol
Hycortole
Hydracort
Hydrasson
Hydro-Adreson
Hydro-Colisona
Hydro-RX
Hydro-colisona
Hydrocort
Hydrocortal
Hydrocorticosterone
Hydrocortisone
Hydrocortisone (JP15/USP/INN)
Hydrocortisone Acetate
Hydrocortisone Base
Hydrocortisone Butyrate
Hydrocortisone Sodium Phosphate
Hydrocortisone Valerate
Hydrocortisone [INN:BAN:JAN]
Hydrocortisone alcohol
Hydrocortisone base
Hydrocortisone free alcohol
Hydrocortisone solution
Hydrocortisone-Water Soluble
Hydrocortisonum
Hydrocortisonum [INN-Latin]
Hydrocortistab
Hydrocortisyl
Hydrocortone
Hydroskin
Hydroxycortisone
Hysone
Hytisone
Hytone
Hytone (TN)
Hytone lotion
Idrocortisone
Idrocortisone [DCIT]
Incortin-H
Incortin-hydrogen
Kendall'S compound F
Kendall's compound F
Komed HC
Kyypakkaus
LMST02030001
LS-7439
Lacticare HC
Lacticare-HC
Lactisona
Lopac0_000594
Lubricort
MLS000069609
MLS001148103
MLS002207135
MLS002222189
Maintasone
Medicort
Meusicort
Mildison
Milliderm
MolPort-001-794-637
NCGC00022848-06
NCGC00022848-07
NCGC00022848-09
NCGC00022848-12
NCI60_000118
NSC 10483
NSC-10483
NSC10483
Neo-Cort-Dome
Neo-Cortef
Neosporin-H Ear
Nogenic HC
Nutracort
Nystaform-HC
ORLEX HC
Optef
Otalgine
Otic-Neo-Cort-Dome
Otobiotic
Otocort
Otosone-F
Pediotic Suspension
Penecort
Permicort
Polcort H
Preparation H Hydrocortisone Cream
Prepcort
Prestwick0_000447
Prestwick1_000447
Prestwick2_000447
Prestwick3_000447
Prestwick_265
Prevex HC
Proctocort
Proctofoam
Proctozone HC
Protocort
Racet
Rectasol-HC
Rectoid
Reichstein'S substance M
Reichstein's substance M
Remederm HC
S1696_Selleck
SAM002264617
SMP1_000156
SMR000059022
SMR000653523
SPBio_002433
Sanatison
Scalp-Cort
Scalpicin Capilar
Schericur
Scheroson F
Sigmacort
Signef
Stie-cort
Stiefcorcil
Synacort
Systral Hydrocort
Tarcortin
Texacort
Texacort lotion 25
Timocort
Topicort
Transderma H
Traumaide
UNII-WI4X0X7BPJ
UPCMLD-DP133
UPCMLD-DP133:001
Uniderm
Vioform-Hydrocortisone
VoSol HC
Vytone
Zenoxone
[3H]cortisol
component of Lubricort
component of Neo-Cort-Dome
component of Otalgine
hydrocortisone
7arginineNutraceutical393

Interventional clinical trials:

(show all 14)
idNameStatusNCT IDPhase
1Changes of Left Ventricular Mass and Cardiac Function in Patients With Active Acromegaly During Treatment With the Growth Hormone Receptor Antagonist PegvisomantRecruitingNCT00552851Phase 4
2The Penumbra Liberty Trial: Safety and Effectiveness in the Treatment of Wide-Neck Intracranial AneurysmsActive, not recruitingNCT01636453Phase 3
3An Efficacy Study of Vagitocin in Postmenopausal Women With Symptoms of Vaginal AtrophyCompletedNCT02497547Phase 2
4Evaluation of Factors in Human Brain TumorsCompletedNCT00001171
5Cardiac and Skeletal Muscle Energy Metabolism in Abnormal Growth Hormone StatesCompletedNCT00461240
6Pelvic Pain in Women With EndometriosisCompletedNCT00073801
7Effects of Hormone Stimulation on Brain Scans for Cushing s DiseaseRecruitingNCT01459237Phase 0
8Evaluation and Treatment of Neurosurgical DisordersRecruitingNCT00060541
9Prospective Study of Clinically Nonfunctioning Pituitary AdenomasRecruitingNCT01556230
10Late Effects of Radiosurgery on Acromegaly StudyRecruitingNCT02296216
11Testing the Developmental Origins HypothesisRecruitingNCT01545492
12Pegvisomant With Glucagon Test to Assess for Adult Growth Hormone DeficiencyRecruitingNCT01804413
13Cushing´s Disease Epidemiology in SwedenActive, not recruitingNCT02350153
14Adult Growth Hormone Deficiency and Cardiovascular RiskTerminatedNCT00720902

Search NIH Clinical Center for Pituitary Apoplexy


Cochrane evidence based reviews: pituitary apoplexy

Genetic Tests for Pituitary Apoplexy

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Anatomical Context for Pituitary Apoplexy

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MalaCards organs/tissues related to Pituitary Apoplexy:

34
Pituitary, Brain, Testes, Prostate, Skeletal muscle, Thyroid, Liver

Animal Models for Pituitary Apoplexy or affiliated genes

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MGI Mouse Phenotypes related to Pituitary Apoplexy:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.1AIP, GNRH1, POMC, PRL
2MP:00053707.9AIP, GNRH1, INS, POMC, PRL
3MP:00107717.9AIP, GNRH1, INS, POMC, PRL
4MP:00053767.5AIP, GNRH1, INS, POMC, PRL
5MP:00053797.2AIP, GNRH1, INS, POMC, PRL

Publications for Pituitary Apoplexy

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Articles related to Pituitary Apoplexy:

(show top 50)    (show all 531)
idTitleAuthorsYear
1
Pituitary apoplexy: pathophysiology, diagnosis and management. (26154095)
2015
2
Pituitary apoplexy presenting with bilateral oculomotor nerve palsy. (26475871)
2015
3
Epistaxis and pituitary apoplexy due to ruptured internal carotid artery aneurysm embedded within pituitary adenoma. (26823732)
2015
4
Pituitary apoplexy. (25732655)
2015
5
Bilateral cerebral infarction in the setting of pituitary apoplexy: a case presentation and literature review. (24965694)
2014
6
Pituitary apoplexy caused by hemorrhage from pituitary metastatic melanoma: case report. (24077271)
2013
7
Pituitary apoplexy: a rare cause of middle cerebral artery infarction. (23749020)
2013
8
Sellar and parasellar intravascular lymphoma mimicking pituitary apoplexy. (22173269)
2012
9
An unusual case of sudden onset headache due to pituitary apoplexy: a case report and review of the new UK guidelines. (22693695)
2012
10
Pituitary metastasis presenting as ischemic pituitary apoplexy following heparin-induced thrombocytopenia. (23129546)
2012
11
Pituitary apoplexy can mimic acute meningoencephalitis or subarachnoid haemorrhage. (21975129)
2011
12
Manifestation of a sellar hemangioblastoma due to pituitary apoplexy: a case report. (21970745)
2011
13
Pituitary apoplexy. (22029023)
2011
14
An objective scoring tool in the management of patients with pituitary apoplexy. (21535071)
2011
15
Sudden onset isolated complete third nerve palsy due to pituitary apoplexy. (21713240)
2011
16
Isolated unilateral abducens cranial nerve palsy: a rare presentation of pituitary apoplexy. (19882540)
2010
17
Hyponatraemia after orthopaedic surgery - a case of pituitary apoplexy. (19335965)
2009
18
Extensive spherical amyloid deposition of pituitary adenoma presenting as pituitary apoplexy. (18280642)
2008
19
Blindness following pituitary apoplexy: timing of surgery and neuro-ophthalmic outcome. (18502643)
2008
20
Intrasellar epidermoid cyst presenting as pituitary apoplexy. (18701295)
2008
21
Perirolandic sparing and pituitary apoplexy in adult brain with global hypoxia. A case report. (24299937)
2007
22
Pituitary apoplexy after thyrotropin-releasing hormone stimulation test in a patient with pituitary macroadenoma. (17908654)
2007
23
Carotid cavernous aneurysm presenting as pituitary apoplexy. (16678729)
2006
24
Pituitary apoplexy in a child presenting with massive subarachnoid and intraventricular hemorrhage. (15639425)
2005
25
Cerebral infarction following pituitary apoplexy--case report. (15600283)
2004
26
Pituitary apoplexy during therapy with cabergoline in an adolescent male with prolactin-secreting macroadenoma. (15761656)
2004
27
Pituitary apoplexy following laparascopic cholocystectomy. (15503190)
2004
28
Pituitary apoplexy occurring during large volume liposuction surgery. (15206436)
2004
29
Suspected pituitary apoplexy in a German shorthaired pointer. (14635962)
2003
30
Pituitary apoplexy presenting as postoperative stupor. (11839866)
2002
31
Pituitary apoplexy presenting as Addisonian crisis after coronary artery bypass grafting. (12224722)
2002
32
Pituitary apoplexy caused by ruptured internal carotid artery aneurysm. (11157198)
2001
33
Massive cerebral infarction as a feature of pituitary apoplexy. (11447445)
2001
34
Perioperative management of a patient requiring surgery for pituitary apoplexy and severe angina pectoris. (11094603)
2000
35
Emergency department presentation of pituitary apoplexy. (10830692)
2000
36
Acute painful oculomotor nerve paresis caused by pituitary apoplexy--a case report. (10465926)
1999
37
Classical pituitary apoplexy: clinical features, management and outcome. (10468988)
1999
38
Pituitary apoplexy following metastasis of bronchogenic adenocarcinoma to a prolactinoma. (10469019)
1999
39
Pituitary apoplexy following mitral valve repair. (9856739)
1998
40
Pituitary apoplexy following the administration of gonadotrophin releasing hormone. (7828363)
1994
41
A retrospective analysis of pituitary apoplexy. (8232799)
1993
42
Pituitary apoplexy and the conflicting perioperative goals of anticoagulation and hemostasis. (8452252)
1993
43
Typical blood-fluid level formation on computerized tomogram in pituitary apoplexy: case report. (2334887)
1990
44
MRI in the diagnosis of so-called pituitary apoplexy: seven cases. (2699619)
1989
45
Silent pituitary apoplexy: subclinical infarction of an adrenocorticotropin-producing pituitary adenoma. (6256408)
1981
46
Acute pituitary vascular accident (pituitary apoplexy). (7206894)
1981
47
Pituitary apoplexy. The importance of skull roentgenograms and computerized tomography in diagnosis. (7382057)
1980
48
Pituitary apoplexy following chlorpromazine stimulation. (718334)
1978
49
Occurrence of growth-hormone deficiency in acromegaly as a result of pituitary apoplexy. (5662169)
1968
50
Hemorrhagic necrosis in pituitary tumors. (Pituitary apoplexy). (5232978)
1967

Variations for Pituitary Apoplexy

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Expression for genes affiliated with Pituitary Apoplexy

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Search GEO for disease gene expression data for Pituitary Apoplexy.

Pathways for genes affiliated with Pituitary Apoplexy

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Pathways related to Pituitary Apoplexy according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.5POMC, PRL
29.4INS, PRL

GO Terms for genes affiliated with Pituitary Apoplexy

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Cellular components related to Pituitary Apoplexy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1secretory granule lumenGO:00347749.9INS, POMC
2extracellular regionGO:00055768.4GNRH1, INS, POMC, PRL

Biological processes related to Pituitary Apoplexy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1glucose homeostasisGO:00425939.6INS, POMC
2cellular protein metabolic processGO:00442679.4INS, PRL
3female pregnancyGO:00075659.3GNRH1, PRL
4cell-cell signalingGO:00072678.6GNRH1, INS, POMC

Molecular functions related to Pituitary Apoplexy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:00051798.4GNRH1, INS, POMC, PRL

Sources for Pituitary Apoplexy

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet