Pituitary Hormone Deficiency, Combined 1 malady

MalaCards: Pituitary Hormone Deficiency, Combined 1, also known as pituitary hormone deficiency, combined, 1, is related to hypopituitarism and combined pituitary hormone deficiency. An important gene associated with Pituitary Hormone Deficiency, Combined 1 is POU1F1 (POU class 1 homeobox 1). Affiliated tissues include pituitary.

OMIM: 613038

pituitary hormone deficiency, combined 1 30 pituitary hormone deficiency, combined, 1 33

hypopituitarism 43 cphd1 30

Disease types for combined pituitary hormone deficiency family:

pituitary hormone deficiency, combined 1	pituitary hormone deficiency, combined 2
pituitary hormone deficiency, combined 3	pituitary hormone deficiency, combined 4

Diseases related to pituitary hormone deficiency, combined 1 by text searches and GeneDecks gene sharing:

(show all 48)

id	Related Disease	Score	Top Affiliating Genes
1	hypopituitarism	10.9
2	combined pituitary hormone deficiency	9.7
3	pituitary hormone deficiency	9.3
4	pituitary hormone deficiency, combined 4	9.0
5	hesx1-related combined pituitary hormone deficiency	8.6
6	lhx4-related combined pituitary hormone deficiency	7.2
7	otx2-related combined pituitary hormone deficiency	7.2
8	pou1f1-related combined pituitary hormone deficiency	7.2
9	prop1-related combined pituitary hormone deficiency	6.5
10	infundibular hypoplasia and hypopituitarism	6.4
11	obesity	6.4
12	sheehan syndrome	6.4
13	septooptic dysplasia	6.4
14	corpus callosum dysgenesis hypopituitarism	6.4
15	familial hypopituitarism	6.4
16	hypopituitarism micropenis cleft lip palate	6.4
17	hypopituitarism postaxial polydactyly	6.4
18	arthrogryposis, distal, with hypopituitarism, mental retardation, and facial anomalies	5.9
19	choroideremia hypopituitarism	5.9
20	growth hormone deficiency	5.9
21	hypothyroidism	5.9
22	kaplowitz bodurtha syndrome	5.9
23	pituitary hypoplasia	5.9
24	anorexia nervosa	4.9
25	pallister-hall syndrome	4.9
26	anterior pituitary insufficiency, familial	4.9
27	panhypopituitarism	4.9
28	aspergillosis	4.9
29	pituitary apoplexy	4.9
30	colon carcinoma	4.9
31	rhyns syndrome	4.9
32	carcinoma	4.9
33	sensorineural hearing loss	4.9
34	dincsoy-salih-patel syndrome	4.9
35	tuberculous meningitis	4.9
36	empty sella syndrome	4.9
37	headache	4.9
38	hemorrhagic fever with renal syndrome	4.9
39	hemorrhagic fever	4.9
40	hearing loss	4.9
41	hyperprolactinemia	4.9
42	21-hydroxylase deficiency	4.9
43	klinefelter's syndrome	4.9
44	acid-labile subunit	4.9
45	lymphocytic hypophysitis	4.9
46	acromegaly	4.9
47	adrenocorticotropic hormone deficiency	4.9
48	myotonic dystrophy	4.9

Clinical features from OMIM: 613038

Approved drugs:

Drug clinical trials:

MalaCards organs/tissues related to pituitary hormone deficiency, combined 1:

²²

Genes related to pituitary hormone deficiency, combined 1 according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	POU1F1	POU class 1 homeobox 1	11.1	Disorders