MCID: PTY004
MIFTS: 25

Pityriasis Lichenoides malady

Summaries for Pityriasis Lichenoides

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42NIH Rare Diseases, 63Wikipedia, 32MalaCards
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NIH Rare Diseases:42 Pityriasis lichenoides is a skin disorder of unknown cause.  there are two types of pityriasis lichenoides; a more severe form with a sudden onset that tends to be short-lived (acute) which is usually found in children, known as pityriasis lichenoides et varioliformis acuta and a more mild but long-lasting (chronic) form known as pityriasis lichenoides chronica. pityriasis lichenoides chronica may clear up in a few weeks or persist for years. last updated: 9/20/2011

MalaCards: Pityriasis Lichenoides is related to cutaneous t cell lymphoma and mycosis fungoides. An important gene associated with Pityriasis Lichenoides is NOS2 (nitric oxide synthase 2, inducible), and among its related pathways are Immune response MIF-mediated glucocorticoid regulation and Immune response Bacterial infections in normal airways. The compounds taurine chloramine and vesnarinone have been mentioned in the context of this disorder. Affiliated tissues include skin, and related mouse phenotypes are immune system and hematopoietic system.

Wikipedia:63 Pityriasis lichenoides is a form of pityriasis. more...

Aliases & Classifications for Pityriasis Lichenoides

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42NIH Rare Diseases, 60UMLS
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Aliases & Descriptions:

pityriasis lichenoides 42 60


Related Diseases for Pityriasis Lichenoides

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Pityriasis Lichenoides:



Diseases related to pityriasis lichenoides

Clinical Features for Pityriasis Lichenoides

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Drugs & Therapeutics for Pityriasis Lichenoides

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Pityriasis Lichenoides

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Anatomical Context for Pityriasis Lichenoides

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32MalaCards
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MalaCards organs/tissues related to Pityriasis Lichenoides:

32
Skin

Animal Models for Pityriasis Lichenoides or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Pityriasis Lichenoides:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053877.5CCR4, TNFRSF8, TNF, CD7, NOS2
2MP:00053977.2CCR4, TNFRSF8, TNF, CD7, NOS2

Publications for Pityriasis Lichenoides

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Genetic Variations for Pityriasis Lichenoides

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Expression for genes affiliated with Pityriasis Lichenoides

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Pityriasis Lichenoides

Search GEO for disease gene expression data for Pityriasis Lichenoides.

Pathways for genes affiliated with Pityriasis Lichenoides

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12EMD Millipore, 29KEGG, 51QIAGEN
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Pathways related to Pityriasis Lichenoides according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5TNF, NOS2
2
Immune response Bacterial infections in normal airways
9.5NOS2, TNF
39.5TNF, NOS2
49.3CD7, TNF
5
Apoptosis and survival Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway
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9.1TNFRSF8, TNF
6
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8.6CCR4, TNFRSF8, TNF
7
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8.6CCR4, TNFRSF8, TNF

Compounds for genes affiliated with Pityriasis Lichenoides

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44Novoseek, 59Tocris Bioscience, 2BitterDB, 28IUPHAR
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Compounds related to Pityriasis Lichenoides according to GeneCards/GeneDecks:

(show all 17)
idCompoundScoreTop Affiliating Genes
1taurine chloramine449.8TNF, NOS2
2vesnarinone449.8NOS2, TNF
3apocynin44 5910.8NOS2, TNF
4triptolide449.8TNF, NOS2
5parthenolide44 210.8NOS2, TNF
6ciglitazone44 2810.7NOS2, TNF
7ns 39844 5910.7TNF, NOS2
8polyinosinic-polycytidylic acid449.7TNF, NOS2
9alpha lipoic acid449.7TNF, NOS2
10l-nmma449.6TNF, NOS2
11diphenyleneiodonium449.6TNF, NOS2
12pdtc449.5TNF, NOS2
13tarc449.5TNF, CCR4
14ccl344 2810.4TNF, CCR4
15[alcl]449.4TNFRSF8, CCR4
16c2ceramide449.4TNF, NOS2
1715-deoxy-delta-12,14-prostaglandin j2449.2NOS2, TNF

GO Terms for genes affiliated with Pityriasis Lichenoides

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16Gene Ontology
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Biological processes related to Pityriasis Lichenoides according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1regulation of insulin secretionGO:0507969.5NOS2, TNF
2negative regulation of gene expressionGO:0106299.2NOS2, TNF
3tumor necrosis factor-mediated signaling pathwayGO:0332099.1TNF, TNFRSF8
4inflammatory responseGO:0069548.9NOS2, TNF, CCR4

Products for genes affiliated with Pityriasis Lichenoides

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Pityriasis Lichenoides

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet