MCID: PTY004
MIFTS: 24

Pityriasis Lichenoides malady

Category: Rare diseases

Aliases & Classifications for Pityriasis Lichenoides

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Aliases & Descriptions for Pityriasis Lichenoides:

Name: Pityriasis Lichenoides 48 68

Classifications:



Summaries for Pityriasis Lichenoides

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NIH Rare Diseases:48 Pityriasis lichenoides (PL) is a skin condition characterized by small, raised pink spots that tend to come together in groups. It is not contagious. There are two main types of PL: an acute form called pityriasis lichenoides et varioliformis acuta (PLEVA), and a milder, longer-lasting form called pityriasis lichenoides chronica (PLC). There is also a rare, severe variant of PLEVA called febrile ulceronecrotic PLEVA, associated with high fever and complications that may affect other body systems. In both types of PL, spots usually occur on the trunk, buttox, arms and legs. PLEVA begins abruptly and may cause itching or burning. PLC may develop over days, is less irritating, and lasts longer than PLEVA. Spots associated with PLC typically fade within 3 to 4 weeks, but new spots may then appear. There is no clear consensus regarding how long either form of PL lasts, but most cases resolve on their own within one to several months. Some cases may wax and wane, or relapse over a period of years. The cause of PL is not known. Theories on the cause have included the possibility of a low-grade or self-limited lymphoproliferative disorder; a reaction to a bacterial or viral infection; and an inappropriate, inflammatory immune response to an unknown foreign agent. Treatment options may include antibiotics, phototherapy, PUVA, or medications that suppress the immune system response (immunosuppressants) in severe cases. Last updated: 1/9/2017

MalaCards based summary: Pityriasis Lichenoides is related to hodgkin lymphoma and pityriasis lichenoides et varioliformis acuta. An important gene associated with Pityriasis Lichenoides is MS4A1 (Membrane Spanning 4-Domains A1), and among its related pathways are B Cell Development Pathways and Hematopoietic cell lineage. Affiliated tissues include t cells, skin and tongue, and related mouse phenotypes are hematopoietic system and immune system.

Wikipedia:71 Pityriasis lichenoides is a form of pityriasis. more...

Related Diseases for Pityriasis Lichenoides

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Graphical network of the top 20 diseases related to Pityriasis Lichenoides:



Diseases related to pityriasis lichenoides

Symptoms & Phenotypes for Pityriasis Lichenoides

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MGI Mouse Phenotypes related to Pityriasis Lichenoides according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053978.8CD7, MS4A1, NOS2, TNFRSF8
2MP:00053878.1CD7, MS4A1, NOS2, TNFRSF8

Drugs & Therapeutics for Pityriasis Lichenoides

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Pityriasis Lichenoides

Genetic Tests for Pityriasis Lichenoides

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Anatomical Context for Pityriasis Lichenoides

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MalaCards organs/tissues related to Pityriasis Lichenoides:

36
T cells, Skin, Tongue

Publications for Pityriasis Lichenoides

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Articles related to Pityriasis Lichenoides:

(show top 50)    (show all 243)
idTitleAuthorsYear
1
Pityriasis lichenoides chronica-like drug eruption developing during pembrolizumab treatment for metastatic melanoma. (27570820)
2016
2
Pityriasis lichenoides chronica presenting with bilateral palmoplantar involvement. (27274548)
2016
3
Pityriasis Lichenoides-like Mycosis Fungoides: Clinical and Histologic Features and Response to Phototherapy. (27746631)
2016
4
Systematic Review of Cases of Cutaneous T-Cell Lymphoma Transformation in Pityriasis Lichenoides and Small Plaque Parapsoriasis. (27031678)
2016
5
Pityriasis lichenoides chronica responds to minocycline in three patients. (27261329)
2016
6
Pityriasis Lichenoides et Varioliformis Acuta: Remission with Hypopigmentation. (27301571)
2016
7
Successful treatment of pityriasis lichenoides chronica with narrow-band ultraviolet B therapy in a patient with Keratitis-Ichthyosis-Deafness syndrome: a case report. (27617521)
2016
8
Phototherapy for Pityriasis Lichenoides in the Pediatric Population: A Review of the Published Literature. (27502793)
2016
9
Differentiation of pityriasis lichenoides chronica from guttate psoriasis by dermoscopy. (25682853)
2015
10
Lichen striatus and pityriasis lichenoides chronica in an 11-year-old girl: An etiologic relationship? (26338752)
2015
11
Adalimumab-Induced Pityriasis Lichenoides Chronica That Responded Well to Methotrexate in a Patient With Psoriasis. (26522235)
2015
12
Pityriasis lichenoides et varioliformis acuta after influenza vaccine. (26312710)
2015
13
Etanercept-induced pityriasis lichenoides chronica in a patient with rheumatoid arthritis. (25789178)
2015
14
Commentary about papular mycosis fungoides, lymphomatoid papulosis, and lymphomatoid pityriasis lichenoides: More similarities than differences. (26566599)
2015
15
Successful therapy of cyclosporin A in pityriasis lichenoides et varioliformis acuta preceded by hand, foot and mouth disease. (26669500)
2015
16
Pityriasis Lichenoides in Childhood: Review of Clinical Presentation and Treatment Options. (25816855)
2015
17
Lymphomatoid papulosis misdiagnosed as pityriasis lichenoides et varioliformis acuta: Two case reports and a literature review. (25371758)
2014
18
Adult pityriasis lichenoides-like mycosis fungoides: a clinical variant of mycosis fungoides. (24961281)
2014
19
I^I' T cell-rich variants of pityriasis lichenoides and lymphomatoid papulosis: benign cutaneous disorders to be distinguished from aggressive cutaneous I^I' T cell lymphomas. (25143223)
2014
20
Pityriasis lichenoides in an Asian population. (23488769)
2013
21
Narrow-band UVB phototherapy for pediatric generalized pityriasis lichenoides. (24112386)
2013
22
Is narrowband ultraviolet B monotherapy effective in the treatment of pityriasis lichenoides? (23786570)
2013
23
Phototherapy for pityriasis lichenoides: our experience. (22974328)
2013
24
Febrile ulceronecrotic Mucha-Habermann disease (pityriasis lichenoides et varioliformis acuta fulminans) associated with parvovirus infection. (23612031)
2013
25
Pityriasis lichenoides-like secondary syphilis and neurosyphilis in a HIV-infected patient. (24278062)
2013
26
Pityriasis lichenoides in a 9-month-old boy. (23177392)
2013
27
The relevance of recognizing clinical and morphologic features of pityriasis lichenoides: clinicopathological study of 29 cases. (24282656)
2013
28
Assessment of the 'no eosinophils' rule: are eosinophils truly absent in pityriasis lichenoides, connective tissue disease, and graft-vs.-host disease? (22443393)
2012
29
Pityriasis lichenoides chronica associated with use of HMG-CoA reductase inhibitors. (23620974)
2012
30
Pityriasis lichenoides et varioliformis acuta associated with subcutaneous immunoglobulin administration. (22980275)
2012
31
Pityriasis lichenoides et varioliformis acuta: case report and review of the literature. (22548038)
2012
32
Demonstration of Treponema pallidum by immunohistochemistry in a patient with secondary syphilis mimicking pityriasis lichenoides chronica. (22142451)
2012
33
Mycosis fungoides following pityriasis lichenoides: an exceptional event or a potential evolution? (22162399)
2012
34
Pityriasis lichenoides. (23255714)
2012
35
Mycosis fungoides following pityriasis lichenoides: an exceptional event or a potential evolution. (21898782)
2012
36
Pemetrexed-induced pityriasis lichenoides-like dermatitis. (22168779)
2012
37
Pityriasis lichenoides et varioliformis acuta: a rare association with the measles, mumps and rubella vaccine. (23157791)
2012
38
Febrile ulceronecrotic Mucha-Habermann disease (pityriasis lichenoides et varioliformis acuta fulminans) presenting as Stevens-Johnson syndrome. (22084981)
2012
39
Pityriasis lichenoides chronica associated with herpes simplex virus type 2. (23243523)
2012
40
CD8-positive pityriasis lichenoides-like mycosis fungoides. (22614934)
2012
41
Childhood pityriasis lichenoides and oral erythromycin. (22639857)
2012
42
Pityriasis lichenoides et varioliformis acuta with numerous CD30(+) cells: a variant mimicking lymphomatoid papulosis and other cutaneous lymphomas. A clinicopathologic, immunohistochemical, and molecular biological study of 13 cases. (22472952)
2012
43
Pityriasis lichenoides chronic after measles-mumps-rubella vaccination. (21967266)
2012
44
Pityriasis lichenoides and varioliformis acuta in pregnancy. (21470218)
2012
45
Varicella-Zoster Virus As a Possible Cause of Pityriasis Lichenoides et Varioliformis Acuta. (22938395)
2012
46
Pityriasis lichenoides et varioliformis acuta exacerbated after tonsillectomy. (21719399)
2011
47
Localized acral pityriasis lichenoides chronica: report of a case. (21352323)
2011
48
Pityriasis lichenoides et varioliformis acuta and pityriasis lichenoides chronica: comparison of lesional T-cell subsets and investigation of viral associations. (21518386)
2011
49
A child with PFAPA syndrome complicated by pityriasis lichenoides et varioliformis acuta. (21504456)
2011
50
Lymphomatoid papulosis followed by pityriasis lichenoides: a common pathogenesis? (22042257)
2011

Variations for Pityriasis Lichenoides

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Expression for genes affiliated with Pityriasis Lichenoides

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Search GEO for disease gene expression data for Pityriasis Lichenoides.

Pathways for genes affiliated with Pityriasis Lichenoides

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Pathways related to Pityriasis Lichenoides according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.5MS4A1, TNFRSF8
29.2CD7, MS4A1

GO Terms for genes affiliated with Pityriasis Lichenoides

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Biological processes related to Pityriasis Lichenoides according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1response to lipopolysaccharideGO:00324969.3NOS2, TNFRSF8

Sources for Pityriasis Lichenoides

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet