MCID: PTY004
MIFTS: 34

Pityriasis Lichenoides malady

Summaries for Pityriasis Lichenoides

Sources:
43NIH Rare Diseases, 64Wikipedia, 33MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
NIH Rare Diseases:43 Pityriasis lichenoides is a skin disorder of unknown cause.  there are two types of pityriasis lichenoides; a more severe form with a sudden onset that tends to be short-lived (acute) which is usually found in children, known as pityriasis lichenoides et varioliformis acuta and a more mild but long-lasting (chronic) form known as pityriasis lichenoides chronica. pityriasis lichenoides chronica may clear up in a few weeks or persist for years. last updated: 9/20/2011

MalaCards: Pityriasis Lichenoides is related to lymphomatoid papulosis and mycosis fungoides. An important gene associated with Pityriasis Lichenoides is NOS2 (nitric oxide synthase 2, inducible), and among its related pathways are Immune response MIF-mediated glucocorticoid regulation and Immune response Bacterial infections in normal airways. The compounds taurine chloramine and vesnarinone have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and b cells, and related mouse phenotypes are immune system and hematopoietic system.

Wikipedia:64 Pityriasis lichenoides is a form of pityriasis. more...

Aliases & Classifications for Pityriasis Lichenoides

Sources:
43NIH Rare Diseases, 61UMLS
See all sources

Aliases & Descriptions:

pityriasis lichenoides 43 61


Related Diseases for Pityriasis Lichenoides

Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Pityriasis Lichenoides:



Diseases related to pityriasis lichenoides

Clinical Features for Pityriasis Lichenoides

Drugs & Therapeutics for Pityriasis Lichenoides

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Pityriasis Lichenoides

Drug clinical trials:

Search ClinicalTrials for Pityriasis Lichenoides

Search NIH Clinical Center for Pityriasis Lichenoides

Search CenterWatch for Pityriasis Lichenoides

Genetic Tests for Pityriasis Lichenoides

Anatomical Context for Pityriasis Lichenoides

Sources:
33MalaCards
See all sources

MalaCards organs/tissues related to Pityriasis Lichenoides:

33
Skin, T cells, B cells, Tongue

Animal Models for Pityriasis Lichenoides or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

MGI Mouse Phenotypes related to Pityriasis Lichenoides:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053877.5CCR4, TNFRSF8, TNF, CD7, NOS2
2MP:00053977.2CCR4, TNFRSF8, TNF, CD7, NOS2

Publications for Pityriasis Lichenoides

Sources:
51PubMed
See all sources

Articles related to Pityriasis Lichenoides:

(show top 50)    (show all 224)
idTitleAuthorsYear
1
Pityriasis lichenoides-like secondary syphilis and neurosyphilis in a HIV-infected patient. (24278062)
2013
2
The relevance of recognizing clinical and morphologic features of pityriasis lichenoides: clinicopathological study of 29 cases. (24282656)
2013
3
Pityriasis lichenoides et varioliformis acuta: a rare association with the measles, mumps and rubella vaccine. (23157791)
2012
4
Pityriasis lichenoides chronica associated with use of HMG-CoA reductase inhibitors. (23620974)
2012
5
Pityriasis lichenoides chronica associated with herpes simplex virus type 2. (23243523)
2012
6
Pityriasis lichenoides. (23255714)
2012
7
Pityriasis lichenoides and varioliformis acuta in pregnancy. (21470218)
2012
8
Resistant pityriasis lichenoides et varioliformis acuta in a 3-year-old boy: successful treatment with methotrexate. (20465649)
2010
9
Pityriasis lichenoides chronica induced by adalimumab therapy for Crohn's disease: report of 2 cases successfully treated with methotrexate. (19821511)
2010
10
Pityriasis lichenoides chronica in black patients. (20408509)
2010
11
Conjunctival Inflammatory Nodule in a Patient with Pityriasis Lichenoides et Varioliformis Acuta. (20740044)
2010
12
The use of synchrotron infrared microspectroscopy in the assessment of cutaneous T-cell lymphoma vs. pityriasis lichenoides chronica. (20415741)
2010
13
Successful association in the treatment of pityriasis lichenoides et varioliformis acuta. (19175486)
2009
14
Presence of chimeric maternally derived keratinocytes in cutaneous inflammatory diseases of children: the example of pityriasis lichenoides. (16374466)
2006
15
The role of cytotoxic skin-homing CD8+ lymphocytes in cutaneous cytotoxic T-cell lymphoma and pityriasis lichenoides. (16112347)
2005
16
Pityriasis lichenoides: a cytotoxic T-cell-mediated skin disorder. Evidence of human parvovirus B19 DNA in nine cases. (15268707)
2004
17
Pityriasis lichenoides chronica. (15748578)
2004
18
Infectious causes of pityriasis lichenoides: a case of fulminant infectious mononucleosis. (12894107)
2003
19
The clonal nature of pityriasis lichenoides. (12164744)
2002
20
T-cell clonality in pityriasis lichenoides: evidence for a premalignant or reactive immune disorder? (12164749)
2002
21
Pityriasis lichenoides et varioliformis acuta during pregnancy. (11763391)
2001
22
Cutaneous T-cell lymphoma presenting with 'segmental pityriasis lichenoides chronica'. (10233610)
1998
23
The transformation of pityriasis lichenoides chronica into parakeratosis variegata in an 11-year-old girl. (9470920)
1997
24
Lymphomatoid papulosis, pityriasis lichenoides et varioliformis acuta, and anaplastic large-cell (Ki-1+) lymphoma. (9270525)
1997
25
Febrile ulceronecrotic pityriasis lichenoides et varioliformis acuta. (7841557)
1994
26
Febrile ulceronecrotic pityriasis lichenoides et varioliformis acuta. (8288786)
1994
27
HIV seropositivity in association with pityriasis lichenoides et varioliformis acuta. (1424257)
1992
28
Atypical manifestations of pityriasis lichenoides chronica: development into paraneoplasia and non-Hodgkin lymphomas of the skin. (1558999)
1992
29
Cutaneous T-cell lymphoma (parapsoriasis en plaque). An association with pityriasis lichenoides et varioliformis acuta in young children. (2241197)
1990
30
Immunohistochemical distinction of lymphomatoid papulosis and pityriasis lichenoides et varioliformis acuta. (1691596)
1990
31
Lichenoid dermatoses and related disorders. II. Lichen nitidus, lichen sclerosus et atrophicus, benign lichenoid keratoses, lichen aureus, pityriasis lichenoides, and keratosis lichenoides chronica. (2180997)
1990
32
Comparative studies of treatments for pityriasis lichenoides. (3312347)
1987
33
Immunohistology of pityriasis lichenoides et varioliformis acuta and pityriasis lichenoides chronica. Evidence for their interrelationship with lymphomatoid papulosis. (2434538)
1987
34
Clinical and histologic features of pityriasis lichenoides et varioliformis acuta in children. (3662566)
1987
35
Ultraviolet light treatment of a patient with pityriasis lichenoides et varioliformis acuta (Mucha-Habermann disease). A case report. (3763706)
1986
36
UV-B phototherapy for pityriasis lichenoides. (4062750)
1985
37
Psoralens and ultraviolet A therapy of pityriasis lichenoides. (6693602)
1984
38
Phototherapy of pityriasis lichenoides. (6847216)
1983
39
Histopathologic diagnosis of pityriasis lichenoides et varioliformis acuta and its clinical correlation. (7092272)
1982
40
Immunofluorescence findings in pityriasis lichenoides. (7000144)
1980
41
Immunofluorescence study of pityriasis lichenoides. (385034)
1979
42
An immunofluorescence study of pityriasis lichenoides. (361062)
1978
43
Hypochromic variant of pityriasis lichenoides chronica. (648022)
1978
44
Pityriasis lichenoides et varioliformis acuta immunohistopathologic study. (15461346)
1977
45
Pityriasis lichenoides. (5070156)
1972
46
Pityriasis lichenoides chronica, Juliusberg? urticaria pigmentosa? (18145554)
1949
47
Pityriasis Lichenoides et Varioliformis Acuta. (19991628)
1938
48
Pityriasis Lichenoides et Varioliformis Acuta (?). Case for Diagnosis. (19986845)
1929
49
Pityriasis Lichenoides et Varioliformis Acuta. (19986777)
1928
50
Pityriasis Lichenoides. (19981655)
1921

Genetic Variations for Pityriasis Lichenoides

Expression for genes affiliated with Pityriasis Lichenoides

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Pityriasis Lichenoides

Search GEO for disease gene expression data for Pityriasis Lichenoides.

Pathways for genes affiliated with Pityriasis Lichenoides

Sources:
12EMD Millipore, 30KEGG, 52QIAGEN
See all sources

Pathways related to Pityriasis Lichenoides according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5TNF, NOS2
2
Immune response Bacterial infections in normal airways
9.5NOS2, TNF
39.5TNF, NOS2
49.3CD7, TNF
5
Apoptosis and survival Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway
Hide members
9.1TNFRSF8, TNF
6
Hide members
8.6CCR4, TNFRSF8, TNF
7
Hide members
8.6CCR4, TNFRSF8, TNF

Compounds for genes affiliated with Pityriasis Lichenoides

Sources:
45Novoseek, 60Tocris Bioscience, 2BitterDB, 29IUPHAR
See all sources

Compounds related to Pityriasis Lichenoides according to GeneCards/GeneDecks:

(show all 17)
idCompoundScoreTop Affiliating Genes
1taurine chloramine459.8TNF, NOS2
2vesnarinone459.8NOS2, TNF
3apocynin45 6010.8NOS2, TNF
4triptolide459.8TNF, NOS2
5parthenolide45 210.8NOS2, TNF
6ciglitazone45 2910.7NOS2, TNF
7ns 39845 6010.7TNF, NOS2
8polyinosinic-polycytidylic acid459.7TNF, NOS2
9alpha lipoic acid459.7TNF, NOS2
10l-nmma459.6TNF, NOS2
11diphenyleneiodonium459.6TNF, NOS2
12pdtc459.5TNF, NOS2
13tarc459.5TNF, CCR4
14ccl345 2910.4TNF, CCR4
15[alcl]459.4TNFRSF8, CCR4
16c2ceramide459.4TNF, NOS2
1715-deoxy-delta-12,14-prostaglandin j2459.2NOS2, TNF

GO Terms for genes affiliated with Pityriasis Lichenoides

Sources:
16Gene Ontology
See all sources

Biological processes related to Pityriasis Lichenoides according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1regulation of insulin secretionGO:0507969.5NOS2, TNF
2negative regulation of gene expressionGO:0106299.2NOS2, TNF
3tumor necrosis factor-mediated signaling pathwayGO:0332099.1TNF, TNFRSF8
4inflammatory responseGO:0069548.9NOS2, TNF, CCR4

Products for genes affiliated with Pityriasis Lichenoides

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Pityriasis Lichenoides

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet