MCID: PTY004
MIFTS: 39

Pityriasis Lichenoides malady

Rare diseases category
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Summaries for Pityriasis Lichenoides

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43NIH Rare Diseases, 65Wikipedia, 33MalaCards
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NIH Rare Diseases:43 Pityriasis lichenoides is a skin disorder of unknown cause.  there are two types of pityriasis lichenoides; a more severe form with a sudden onset that tends to be short-lived (acute) which is usually found in children, known as pityriasis lichenoides et varioliformis acuta and a more mild but long-lasting (chronic) form known as pityriasis lichenoides chronica. pityriasis lichenoides chronica may clear up in a few weeks or persist for years. last updated: 9/20/2011

MalaCards: Pityriasis Lichenoides is related to lymphomatoid papulosis and mycosis fungoides. An important gene associated with Pityriasis Lichenoides is NOS2 (nitric oxide synthase 2, inducible), and among its related pathways are TRAF Pathway and Spinal Cord Injury. The compounds taurine chloramine and vesnarinone have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and tongue, and related mouse phenotypes are respiratory system and hematopoietic system.

Wikipedia:65 Pityriasis lichenoides is a form of pityriasis. more...

Aliases & Classifications for Pityriasis Lichenoides

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43NIH Rare Diseases, 62UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


Aliases & Descriptions:

pityriasis lichenoides 43 62


Related Diseases for Pityriasis Lichenoides

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Pityriasis Lichenoides:



Diseases related to pityriasis lichenoides

Symptoms for Pityriasis Lichenoides

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Drugs & Therapeutics for Pityriasis Lichenoides

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Pityriasis Lichenoides

Search NIH Clinical Center for Pityriasis Lichenoides

Genetic Tests for Pityriasis Lichenoides

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Anatomical Context for Pityriasis Lichenoides

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33MalaCards
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MalaCards organs/tissues related to Pityriasis Lichenoides:

33
Skin, T cells, Tongue

Animal Models for Pityriasis Lichenoides or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Pityriasis Lichenoides:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053889.0NOS2, CCR4, TNF
2MP:00053977.4CD7, NOS2, CCR4, TNF, TNFRSF8
3MP:00053877.2TNFRSF8, TNF, CCR4, NOS2, CD7

Publications for Pityriasis Lichenoides

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52PubMed
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Articles related to Pityriasis Lichenoides:

(show top 50)    (show all 223)
idTitleAuthorsYear
1
Pityriasis lichenoides in an Asian population. (23488769)
2013
2
Narrow-band UVB phototherapy for pediatric generalized pityriasis lichenoides. (24112386)
2013
3
Assessment of the 'no eosinophils' rule: are eosinophils truly absent in pityriasis lichenoides, connective tissue disease, and graft-vs.-host disease? (22443393)
2012
4
Pityriasis lichenoides et varioliformis acuta: a rare association with the measles, mumps and rubella vaccine. (23157791)
2012
5
Pityriasis lichenoides chronica associated with use of HMG-CoA reductase inhibitors. (23620974)
2012
6
Pityriasis lichenoides et varioliformis acuta exacerbated after tonsillectomy. (21719399)
2011
7
Pityriasis lichenoides et varioliformis acuta: a disease spectrum. (20465660)
2010
8
Resistant pityriasis lichenoides et varioliformis acuta in a 3-year-old boy: successful treatment with methotrexate. (20465649)
2010
9
Pityriasis lichenoides et varioliformis acuta in a 2-year-old boy. (19236427)
2009
10
Infliximab-induced pityriasis lichenoides chronica in a patient with psoriasis. (18680531)
2009
11
Role of bromelain in the treatment of patients with pityriasis lichenoides chronica. (17671882)
2007
12
Pityriasis lichenoides: pathophysiology, classification, and treatment. (17298104)
2007
13
Pityriasis lichenoides and its subtypes. (17010734)
2006
14
UVB therapy of pityriasis lichenoides--our experience with 29 patients. (16684281)
2006
15
The role of cytotoxic skin-homing CD8+ lymphocytes in cutaneous cytotoxic T-cell lymphoma and pityriasis lichenoides. (16112347)
2005
16
Picture of the month. Pityriasis lichenoides et varioliformis acuta. (16203944)
2005
17
Septic, CD-30 positive febrile ulceronecrotic pityriasis lichenoides et varioliformis acuta. (16060878)
2005
18
Pityriasis lichenoides et varioliformis acuta. (12657766)
2003
19
Pityriasis lichenoides: a clonal T-cell lymphoproliferative disorder. (12203210)
2002
20
Pityriasis lichenoides et varioliformis acuta in pregnancy. Does it affect pregnancy outcome? (12235483)
2002
21
Medium-dose ultraviolet A1 therapy for pityriasis lichenoides et varioliformis acuta and pityriasis lichenoides chronica. (12196751)
2002
22
Pityriasis lichenoides et varioliformis acuta in pregnancy. (11802190)
2001
23
Pityriasis lichenoides et varioliformis acuta during pregnancy. (11763391)
2001
24
Successful long-term use of cyclosporin A in HIV-induced pityriasis lichenoides chronica. (9704950)
1998
25
The transformation of pityriasis lichenoides chronica into parakeratosis variegata in an 11-year-old girl. (9470920)
1997
26
Febrile ulceronecrotic pityriasis lichenoides et varioliformis acuta. (7841557)
1994
27
Lymphomatoid papulosis: clinicopathological comparative study with pityriasis lichenoides et varioliformis acuta. (1665158)
1991
28
Cutaneous T-cell lymphoma (parapsoriasis en plaque). An association with pityriasis lichenoides et varioliformis acuta in young children. (2241197)
1990
29
Pityriasis lichenoides et varioliformis acuta and acquired toxoplasmosis. (3609416)
1987
30
Clonal T-cell populations in pityriasis lichenoides et varioliformis acuta (Mucha-Habermann disease). (3030116)
1987
31
Psoralens and ultraviolet A therapy of pityriasis lichenoides. (6693602)
1984
32
Long-term follow-up of photochemotherapy in pityriasis lichenoides. (6183900)
1982
33
Immunofluorescence study of pityriasis lichenoides. (385034)
1979
34
Heliotherapy of pityriasis lichenoides chronica. (15461333)
1977
35
Pityriasis lichenoides--an immune complex disease. (146510)
1977
36
Pityriasis lichenoides et varioliformis acuta and suspected cardiomyopathy. (1195179)
1975
37
Pityriasis lichenoides. (5070156)
1972
38
Poikiloderma with pityriasis lichenoides. (5570252)
1971
39
Pityriasis lichenoides et varioliformis "(chronica)". (5440829)
1970
40
On pityriasis lichenoides chronica and prurigo chronica nodularis]. (13083062)
1953
41
Treatment of lichen ruber planus and pityriasis lichenoides chronica with 2-methyl-1; 4-naphthoquinone (vitamin K-like substance). (14818652)
1951
42
Pityriasis lichenoides et varioliformis acuta. (20992539)
1946
43
Pityriasis Lichenoides Chronica (Parapsoriasis Guttata). (19993000)
1945
44
Pityriasis Lichenoides et Varioliformis. (19992114)
1939
45
Pityriasis Lichenoides et Varioliformis Acuta. (19991628)
1938
46
Pityriasis Lichenoides: Case for Diagnosis. (19990188)
1935
47
Pityriasis Lichenoides et Varioliformis Acuta. (19987314)
1930
48
Pityriasis Lichenoides et Varioliformis Acuta. (19985540)
1927
49
Case of Pityriasis Lichenoides Chronica. (19984295)
1925
50
Pityriasis Lichenoides Chronica. (19980918)
1920

Variations for Pityriasis Lichenoides

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Expression for genes affiliated with Pityriasis Lichenoides

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Pityriasis Lichenoides

Search GEO for disease gene expression data for Pityriasis Lichenoides.

Pathways for genes affiliated with Pityriasis Lichenoides

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50PathCards, 53QIAGEN, 38NCBI BioSystems Database, 60Thomson Reuters, 30KEGG, 54R&D Systems, 57SinoBiological
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Pathways related to Pityriasis Lichenoides according to GeneCards/GeneDecks:

(show all 19)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
10.0TNF
29.5NOS2, TNF
39.5NOS2, TNF
4
Show member pathways
IL23-mediated signaling events38
Immune response IL 10 signaling pathway60
Angiopoietin receptor Tie2-mediated signaling38
Development PDGF signaling via STATs and NF kB60
Development Angiopoietin Tie2 signaling60
9.5NOS2, TNF
5
Show member pathways
9.5NOS2, TNF
6
Show member pathways
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways60
Immune response IL 1 signaling pathway60
9.5NOS2, TNF
79.5NOS2, TNF
8
Show member pathways
Immune response MIF in innate immunity response60
9.5TNF, NOS2
99.5NOS2, TNF
109.5TNF, NOS2
11
Show member pathways
Transcription NF kB signaling pathway60
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response60
9.5NOS2, TNF
129.3CD7, TNF
13
Show member pathways
Alternative NF-kappaB pathway38
9.1TNF, TNFRSF8
14
Show member pathways
Apoptosis and survival Anti apoptotic TNFs NF kB IAP pathway60
9.1TNF, TNFRSF8
15
Show member pathways
9.1TNF, TNFRSF8
16
Show member pathways
8.6CCR4, TNF, TNFRSF8
17
Show member pathways
8.6TNFRSF8, TNF, CCR4
18
Show member pathways
8.6TNFRSF8, TNF, CCR4
19
Show member pathways
8.6TNFRSF8, TNF, CCR4

Compounds for genes affiliated with Pityriasis Lichenoides

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45Novoseek, 61Tocris Bioscience, 3BitterDB, 29IUPHAR, 11DrugBank, 51PharmGKB, 24HMDB
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Compounds related to Pityriasis Lichenoides according to GeneCards/GeneDecks:

(show all 26)
idCompoundScoreTop Affiliating Genes
1taurine chloramine459.9NOS2, TNF
2vesnarinone459.9NOS2, TNF
3apocynin45 6110.9TNF, NOS2
4triptolide459.8NOS2, TNF
5parthenolide45 310.8TNF, NOS2
6ciglitazone45 2910.8TNF, NOS2
7ns 39845 6110.8NOS2, TNF
8polyinosinic-polycytidylic acid459.8NOS2, TNF
9alpha lipoic acid459.8TNF, NOS2
10l-nmma459.8NOS2, TNF
11diphenyleneiodonium459.8NOS2, TNF
12c2ceramide459.8NOS2, TNF
1315-deoxy-delta-12,14-prostaglandin j2459.7NOS2, TNF
14pdtc459.7NOS2, TNF
15tarc459.7CCR4, TNF
16ccl345 2910.7TNF, CCR4
17egcg459.7NOS2, TNF
18mg 13245 6110.6NOS2, TNF
19prednisolone45 29 1111.6TNF, CCR4
20herbimycin a45 6110.6TNF, NOS2
21simvastatin45 51 61 29 24 1114.5TNF, CCR4
22endotoxin459.5NOS2, TNF
23[alcl]459.5CCR4, TNFRSF8
24curcumin459.4TNF, NOS2
25prostacyclin459.2NOS2, TNF
26lipid458.6CCR4, TNF, TNFRSF8

GO Terms for genes affiliated with Pityriasis Lichenoides

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16Gene Ontology
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Cellular components related to Pityriasis Lichenoides according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:0098979.1CCR4, TNF
2plasma membraneGO:0058868.0CD7, CCR4, TNF, TNFRSF8

Biological processes related to Pityriasis Lichenoides according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to bacteriumGO:0096179.6NOS2, CCR4
2response to hypoxiaGO:0016669.5NOS2, TNF
3negative regulation of gene expressionGO:0106299.4NOS2, TNF
4regulation of insulin secretionGO:0507969.2NOS2, TNF
5tumor necrosis factor-mediated signaling pathwayGO:0332099.1TNFRSF8, TNF
6inflammatory responseGO:0069549.0NOS2, CCR4, TNF

Products for genes affiliated with Pityriasis Lichenoides

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Sources for Pityriasis Lichenoides

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet